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Overview
1.1
1.2
1.3
1.4
1.5
1.6

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_LR822015.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | lanthipeptide-class-i | 95,792 | 119,857 | lactocin S | RiPP:Lanthipeptide | 10%
Region 1.2 | NRPS-like | 264,526 | 307,417 | asukamycin | Polyketide:Type II | 4%
Region 1.3 | RRE-containing | 505,665 | 524,783 |
Region 1.4 | RaS-RiPP | 833,309 | 854,807 |
Region 1.5 | RiPP-like | 1,475,268 | 1,491,550 |
Region 1.6 | lanthipeptide-class-iv,RaS-RiPP | 1,703,108 | 1,729,899 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | lanthipeptide-class-i | 95,792 | 119,857 | lactocin S | RiPP:Lanthipeptide | 10%
Region 1.2 | NRPS-like | 264,526 | 307,417 | asukamycin | Polyketide:Type II | 4%
Region 1.3 | RRE-containing | 505,665 | 524,783 |
Region 1.4 | RaS-RiPP | 833,309 | 854,807 |
Region 1.5 | RiPP-like | 1,475,268 | 1,491,550 |
Region 1.6 | lanthipeptide-class-iv,RaS-RiPP | 1,703,108 | 1,729,899 |

No secondary metabolite regions were found in these records:
  NZ_LR822016.1

Compact view
NZ_LR822015.1 - Region 1 - lanthipeptide-class-i
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 95,792 - 119,857 nt. (total: 24,066 nt) Show pHMM detection rules used
lanthipeptide-class-i: ((LANC_like and (Lant_dehydr_N or Lant_dehydr_C)) and not (YcaO or TIGR03882))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Lanthipeptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-i | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000560.1 |  | 0.19 | RiPP | subtilomycin | Bacillus subtilis
BGC0000506.1 |  | 0.16 | RiPP | entianin | Bacillus subtilis subsp. spizizenii
BGC0000515.1 |  | 0.16 | RiPP | geobacillin I | Geobacillus thermodenitrificans NG80-2
BGC0000559.1 |  | 0.16 | RiPP | subtilin | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001618.1 |  | 0.16 | RiPP | hyicin 3682 | Staphylococcus hyicus
BGC0000508.1 |  | 0.15 | RiPP | epidermin | Staphylococcus epidermidis
BGC0000533.1 |  | 0.12 | RiPP | mutacin III | Streptococcus mutans
BGC0000530.1 |  | 0.12 | RiPP | mutacin B-Ny266 | Streptococcus mutans N66
BGC0000531.1 |  | 0.12 | RiPP | mutacin I | Streptococcus mutans
BGC0000523.1 |  | 0.11 | RiPP | lactocin S | Lactobacillus sakei

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000560.1 |  | 0.51 | RiPP | subtilomycin | Bacillus subtilis
BGC0000506.1 |  | 0.47 | RiPP | entianin | Bacillus subtilis subsp. spizizenii
BGC0000515.1 |  | 0.47 | RiPP | geobacillin I | Geobacillus thermodenitrificans NG80-2
BGC0000559.1 |  | 0.46 | RiPP | subtilin | Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001618.1 |  | 0.46 | RiPP | hyicin 3682 | Staphylococcus hyicus
BGC0000508.1 |  | 0.46 | RiPP | epidermin | Staphylococcus epidermidis
BGC0000533.1 |  | 0.40 | RiPP | mutacin III | Streptococcus mutans
BGC0000530.1 |  | 0.40 | RiPP | mutacin B-Ny266 | Streptococcus mutans N66
BGC0000531.1 |  | 0.39 | RiPP | mutacin I | Streptococcus mutans
BGC0000523.1 |  | 0.38 | RiPP | lactocin S | Lactobacillus sakei

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Lanthipeptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash.
Lanthipeptides - No core peptides found.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.
No core peptides found.
NZ_LR822015.1 - Region 2 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 264,526 - 307,417 nt. (total: 42,892 nt) Show pHMM detection rules used
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000558.1 |  | 0.24 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000554.1 |  | 0.23 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000539.1 |  | 0.23 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0000504.1 |  | 0.22 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0001407.1 |  | 0.21 | RiPP | bicereucin | Bacillus cereus SJ1
BGC0001862.1 |  | 0.21 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.21 | RiPP | pallidocin | Aeribacillus pallidus
BGC0000500.1 |  | 0.20 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0001861.1 |  | 0.20 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1
BGC0001591.1 |  | 0.20 | Other | fatty acid enol ester | uncultured bacterium CSLC2

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000558.1 |  | 0.57 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000554.1 |  | 0.56 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000539.1 |  | 0.56 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0000504.1 |  | 0.55 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0001407.1 |  | 0.54 | RiPP | bicereucin | Bacillus cereus SJ1
BGC0001862.1 |  | 0.53 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.53 | RiPP | pallidocin | Aeribacillus pallidus
BGC0000500.1 |  | 0.53 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0001861.1 |  | 0.53 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1
BGC0001591.1 |  | 0.52 | Other | fatty acid enol ester | uncultured bacterium CSLC2

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_LR822015.1 - Region 3 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 505,665 - 524,783 nt. (total: 19,119 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000585.1 |  | 0.26 | RiPP | microcin C7 | Escherichia coli
BGC0000551.1 |  | 0.18 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0000496.1 |  | 0.17 | RiPP | AmfS | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000519.1 |  | 0.17 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0000626.1 |  | 0.16 | RiPP | thuricin | Bacillus thuringiensis
BGC0001526.1 |  | 0.16 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0000521.1 |  | 0.16 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000616.1 |  | 0.16 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000486.1 |  | 0.16 | RiPP | butyrivibriocin AR10 | Butyrivibrio fibrisolvens
BGC0000501.1 |  | 0.16 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000585.1 |  | 0.59 | RiPP | microcin C7 | Escherichia coli
BGC0000551.1 |  | 0.50 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0000496.1 |  | 0.48 | RiPP | AmfS | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000519.1 |  | 0.48 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0000626.1 |  | 0.47 | RiPP | thuricin | Bacillus thuringiensis
BGC0001526.1 |  | 0.47 | Other | bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K | Synechocystis salina LEGE 06099
BGC0000521.1 |  | 0.46 | RiPP | lacticin 481 | Lactococcus lactis subsp. lactis
BGC0000616.1 |  | 0.46 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000486.1 |  | 0.46 | RiPP | butyrivibriocin AR10 | Butyrivibrio fibrisolvens
BGC0000501.1 |  | 0.46 | RiPP | catenulipeptin | Catenulispora acidiphila DSM 44928

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_LR822015.1 - Region 4 - RaS-RiPP
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 833,309 - 854,807 nt. (total: 21,499 nt) Show pHMM detection rules used
RaS-RiPP: (PF04055 and TIGR01716)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RaS-RiPP | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001209.1 |  | 0.43 | RiPP | streptide | Streptococcus thermophilus LMD-9
BGC0001929.1 |  | 0.22 | RiPP | WGK | Streptococcus ferus
BGC0001156.1 |  | 0.21 | Terpene | platencin | Streptomyces platensis
BGC0001140.1 |  | 0.21 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0000228.1 |  | 0.17 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0000010.1 |  | 0.16 | Polyketide | aflatoxin | Aspergillus flavus
BGC0000523.1 |  | 0.16 | RiPP | lactocin S | Lactobacillus sakei
BGC0000207.1 |  | 0.15 | Polyketide | chartreusin | Streptomyces chartreusis
BGC0001605.1 |  | 0.15 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001783.1 |  | 0.15 | Other | streptonigrin | Streptomyces flocculus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001209.1 |  | 0.74 | RiPP | streptide | Streptococcus thermophilus LMD-9
BGC0001929.1 |  | 0.55 | RiPP | WGK | Streptococcus ferus
BGC0001156.1 |  | 0.53 | Terpene | platencin | Streptomyces platensis
BGC0001140.1 |  | 0.53 | Terpene | platensimycin, platencin | Streptomyces platensis
BGC0000228.1 |  | 0.48 | Polyketide | granaticin | Streptomyces violaceoruber
BGC0000010.1 |  | 0.47 | Polyketide | aflatoxin | Aspergillus flavus
BGC0000523.1 |  | 0.47 | RiPP | lactocin S | Lactobacillus sakei
BGC0000207.1 |  | 0.46 | Polyketide | chartreusin | Streptomyces chartreusis
BGC0001605.1 |  | 0.46 | Terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001783.1 |  | 0.44 | Other | streptonigrin | Streptomyces flocculus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_LR822015.1 - Region 5 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,475,268 - 1,491,550 nt. (total: 16,283 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000624.1 |  | 0.41 | RiPP | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0001388.1 |  | 0.40 | RiPP | gassericin E | Lactobacillus gasseri
BGC0000619.1 |  | 0.40 | RiPP | gassericin T | Lactobacillus gasseri
BGC0001602.1 |  | 0.40 | RiPP | gassericin-T | Lactobacillus gasseri
BGC0000617.1 |  | 0.31 | RiPP | coagulin | Bacillus coagulans
BGC0000558.1 |  | 0.23 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000554.1 |  | 0.21 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000519.1 |  | 0.17 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0000513.1 |  | 0.16 | RiPP | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000551.1 |  | 0.16 | RiPP | SapB | Streptomyces coelicolor A3(2)

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000624.1 |  | 0.72 | RiPP | salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide | Lactobacillus salivarius
BGC0001388.1 |  | 0.72 | RiPP | gassericin E | Lactobacillus gasseri
BGC0000619.1 |  | 0.72 | RiPP | gassericin T | Lactobacillus gasseri
BGC0001602.1 |  | 0.72 | RiPP | gassericin-T | Lactobacillus gasseri
BGC0000617.1 |  | 0.65 | RiPP | coagulin | Bacillus coagulans
BGC0000558.1 |  | 0.56 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000554.1 |  | 0.54 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000519.1 |  | 0.48 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0000513.1 |  | 0.47 | RiPP | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000551.1 |  | 0.47 | RiPP | SapB | Streptomyces coelicolor A3(2)

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_LR822015.1 - Region 6 - RaS-RiPP,lanthipeptide-class-iv
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,703,108 - 1,729,899 nt. (total: 26,792 nt) Show pHMM detection rules used
lanthipeptide-class-iv: (cds(LANC_like and Pkinase) and not micKC)
RaS-RiPP: (PF04055 and TIGR01716)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Lanthipeptides
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-iv | RaS-RiPP | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001209.1 |  |  | 0.72 | RiPP | streptide | Streptococcus thermophilus LMD-9
BGC0001929.1 |  |  | 0.59 | RiPP | WGK | Streptococcus ferus
BGC0000519.1 |  |  | 0.51 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0001733.1 |  |  | 0.41 | RiPP | PcpA | Pleurocapsa sp. PCC 7327
BGC0000551.1 |  |  | 0.41 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0000601.1 |  |  | 0.40 | RiPP | sporulation killing factor | Bacillus subtilis subsp. subtilis str. 168
BGC0000513.1 |  |  | 0.40 | RiPP | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000626.1 |  |  | 0.39 | RiPP | thuricin | Bacillus thuringiensis
BGC0000539.1 |  |  | 0.39 | RiPP | nukacin ISK-1 | Staphylococcus warneri
BGC0000500.1 |  |  | 0.38 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001209.1 |  | 0.69 | RiPP | streptide | Streptococcus thermophilus LMD-9
BGC0001929.1 |  | 0.63 | RiPP | WGK | Streptococcus ferus
BGC0000519.1 |  | 0.59 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0001733.1 |  | 0.53 | RiPP | PcpA | Pleurocapsa sp. PCC 7327
BGC0000551.1 |  | 0.53 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0000601.1 |  | 0.52 | RiPP | sporulation killing factor | Bacillus subtilis subsp. subtilis str. 168
BGC0000513.1 |  | 0.52 | RiPP | Ery-9, Ery-6, Ery-8, Ery-7, Ery-5, Ery-4, Ery-3 | Saccharopolyspora erythraea NRRL 2338
BGC0000626.1 |  | 0.52 | RiPP | thuricin | Bacillus thuringiensis
BGC0000497.1 |  | 0.52 | RiPP | BHT-Aα, BHT-Aβ | Streptococcus ratti
BGC0000539.1 |  | 0.51 | RiPP | nukacin ISK-1 | Staphylococcus warneri

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lanthipeptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash.
Lanthipeptides - No core peptides found.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.
No core peptides found.