LOCUS       NZ_LR793266.1          22790 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LR793266.1 Streptococcus salivarius isolate clinical strain from
            anonymous patient of Limoges Hospital, whole genome shotgun
            sequence.
ACCESSION   NZ_LR793266
VERSION     NZ_LR793266.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:57:27
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1820436
            Orig. end    :: 1843226
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22790
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1825436:1838226]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..17790
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..22790
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22790
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="3"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     PFAM_domain     497..922
                     /aSDomain="PepX_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09168.12"
                     /description="X-Prolyl dipeptidyl aminopeptidase PepX,
                     N-terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1568_0074"
                     /evalue="1.30E-39"
                     /label="ctg1_1568"
                     /locus_tag="ctg1_1568"
                     /protein_end="142"
                     /protein_start="0"
                     /score="136.2"
                     /tool="antismash"
                     /translation="MKFNQFSYIPVNPEIACQELRSLGFEVSLNASAKANFEAFVRKHF
                     LFFEDTDLALKNWIADTETDLLTFFQSDRPLTADVFGLVALQMLGFVPNVDFTDSAAFL
                     EEMAFPITFDGSLNNLHQLLATRTQSGNTLIDQLVAQD"
     CDS             497..2764
                     /locus_tag="ctg1_1568"
                     /transl_table=11
                     /translation="MKFNQFSYIPVNPEIACQELRSLGFEVSLNASAKANFEAFVRKHF
                     LFFEDTDLALKNWIADTETDLLTFFQSDRPLTADVFGLVALQMLGFVPNVDFTDSAAFL
                     EEMAFPITFDGSLNNLHQLLATRTQSGNTLIDQLVAQDLIPVSNNYIFFNGKSLATFDT
                     NQLHREVVYVETPVDTDKDGQLDLVKVTILRPDVDFPVPAMMTASPYQQGTNEPASDKL
                     THKMEGDLLVKPAGEISLSQPEIKAPEVDLTPINPVTKAQERFAHTDTYTLNDYMLARG
                     VASIYVSGVGTFNSEGFMTSGDYQQVLAYKAVIDWLNGRARAFTSRSRQHTITADWASG
                     KVTTTGLSYLGTMSNALATTGVDGLEMVIAEAGISSWYDYYRENGLLVSPGGYPGEDLD
                     TLTEFTYSRALLAGEYLRHQKDYQAYLKELSTAIDRKHGDYSQFWHDRNYVQFADRVKA
                     TVVFTHGSQDWNVKPINVYQMFNALPDTLEKHLFFHNGAHVYMNAWQSIDFRESMNALI
                     CQKLLGLENGYTLPTLIWQNNQSEQTWEVLDNFGHNNGKIIQLGEAEASIANHYEEETF
                     TKYGKAYQSFKDDLFADKANAITLDFELDQDIQINGRVHLELKVKSSTNRGLISAQVLE
                     MGDKKYLAPIPALKRMNLDNGRLFKEEALRELPFKQEKYRVITKGHLNLQNRKDLLSVE
                     NVSPNEWMTIGLDLQPTIYKLNKGDKLRLVLYTTDFEHTIRDNSNYELTVDLSQSQMTL
                     PY"
     PFAM_domain     1040..1996
                     /aSDomain="Peptidase_S15"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02129.20"
                     /description="X-Pro dipeptidyl-peptidase (S15 family)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1568_0075"
                     /evalue="2.10E-75"
                     /label="ctg1_1568"
                     /locus_tag="ctg1_1568"
                     /protein_end="500"
                     /protein_start="181"
                     /score="253.9"
                     /tool="antismash"
                     /translation="DGQLDLVKVTILRPDVDFPVPAMMTASPYQQGTNEPASDKLTHKM
                     EGDLLVKPAGEISLSQPEIKAPEVDLTPINPVTKAQERFAHTDTYTLNDYMLARGVASI
                     YVSGVGTFNSEGFMTSGDYQQVLAYKAVIDWLNGRARAFTSRSRQHTITADWASGKVTT
                     TGLSYLGTMSNALATTGVDGLEMVIAEAGISSWYDYYRENGLLVSPGGYPGEDLDTLTE
                     FTYSRALLAGEYLRHQKDYQAYLKELSTAIDRKHGDYSQFWHDRNYVQFADRVKATVVF
                     THGSQDWNVKPINVYQMFNALPDTLEKHLFFHNGAHVY"
     PFAM_domain     2081..2743
                     /aSDomain="PepX_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08530.12"
                     /description="X-Pro dipeptidyl-peptidase C-terminal
                     non-catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1568_0076"
                     /evalue="3.30E-30"
                     /label="ctg1_1568"
                     /locus_tag="ctg1_1568"
                     /protein_end="749"
                     /protein_start="528"
                     /score="105.7"
                     /tool="antismash"
                     /translation="TLPTLIWQNNQSEQTWEVLDNFGHNNGKIIQLGEAEASIANHYEE
                     ETFTKYGKAYQSFKDDLFADKANAITLDFELDQDIQINGRVHLELKVKSSTNRGLISAQ
                     VLEMGDKKYLAPIPALKRMNLDNGRLFKEEALRELPFKQEKYRVITKGHLNLQNRKDLL
                     SVENVSPNEWMTIGLDLQPTIYKLNKGDKLRLVLYTTDFEHTIRDNSNYELTVDLSQS"
     CDS             complement(2845..3225)
                     /locus_tag="ctg1_1569"
                     /transl_table=11
                     /translation="MSKNLRALTAIVLSQLLIEWMGFFLGIPLSKILVLTVLSSLVEIL
                     MHLFLSKKSKVTLGDKEIWHQYFLFVKKTLWFSILLVAIFLFYSIIKSDSFMLYFYWHI
                     FVLFHCLGYIICLNNIKINRKN"
     CDS             complement(3350..3766)
                     /locus_tag="ctg1_1570"
                     /transl_table=11
                     /translation="MPYLNRLRSGTLLYLRLMVVAFGLIGGNIGLELLYNGSSFLFWLP
                     LALLSIFLLVFPLLIKRELNNRPLEERQFTPKQIYSGMGLAHLAIILAGIYRLLTVRDA
                     EWRLIIIVMIVLDICLLAFLTPRVLKIIKQSERG"
     CDS             complement(3933..4229)
                     /locus_tag="ctg1_1571"
                     /transl_table=11
                     /translation="MTGLKWFAGGKERREQAVAIIDEVIETIGDKPDYADLKQVLYSYR
                     TELADSRSATPYILSRMSLEISEVVRKDQLTLSPCIEERMAELRKLLAIRYGY"
     PFAM_domain     complement(3966..4187)
                     /aSDomain="EntA_Immun"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08951.12"
                     /description="Enterocin A Immunity"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1571_0077"
                     /evalue="5.00E-11"
                     /label="ctg1_1571"
                     /locus_tag="ctg1_1571"
                     /protein_end="88"
                     /protein_start="14"
                     /score="42.8"
                     /tool="antismash"
                     /translation="EQAVAIIDEVIETIGDKPDYADLKQVLYSYRTELADSRSATPYIL
                     SRMSLEISEVVRKDQLTLSPCIEERMAEL"
     CDS             complement(4597..4989)
                     /locus_tag="ctg1_1572"
                     /transl_table=11
                     /translation="MTHRVSKRDIVLFVIAQVVSISLLVLFFSQLLHNLSSVFQLVYIV
                     AALLVVVVDILLIRKIMTRREEPTVLNQLKASLACFLLLTLSCLRFLTTDFYYQKVIAI
                     FVGFFSLLGFVLFLWGIKYINHNIEK"
     CDS             complement(5001..5159)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1573"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.2e-10,
                     bitscore: 38.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTQTIENFNTLDLETLASVEGGRVNWERWGMCGASVAVGATIGG
                     GVALLGC"
     aSDomain        complement(5016..5135)
                     /aSDomain="TIGR03949"
                     /aSTool="tigrfam"
                     /description="bact_IIb_cerein: class IIb bacteriocin,
                     lactobin A/cerein 7B family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1573_0027"
                     /evalue="3.10E-06"
                     /identifier="TIGR03949"
                     /label="ctg1_1573"
                     /locus_tag="ctg1_1573"
                     /protein_end="48"
                     /protein_start="8"
                     /score="24.9"
                     /tool="antismash"
                     /translation="FNTLDLETLASVEGGRVNWERWGMCGASVAVGATIGGGVA"
     PFAM_domain     complement(5022..5141)
                     /aSDomain="Bacteriocin_IIc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10439.11"
                     /description="Bacteriocin class II with double-glycine
                     leader peptide"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1573_0078"
                     /evalue="7.60E-08"
                     /label="ctg1_1573"
                     /locus_tag="ctg1_1573"
                     /protein_end="46"
                     /protein_start="6"
                     /score="32.4"
                     /tool="antismash"
                     /translation="ENFNTLDLETLASVEGGRVNWERWGMCGASVAVGATIGGG"
     CDS             5413..6153
                     /locus_tag="ctg1_1574"
                     /transl_table=11
                     /translation="LDIYILEDNLIQQGRLEMVLSQELKKYNKDLSIVHTFDKPQQFIE
                     AIDSTTSNQLFFLDIEIKGEKLKGLDIAKIIREKNPYATIIFVTTHSEFMPLVFDYQVS
                     ALDYIDKSLSEIEFRKKITRALAITMKPLGIENDEIFDFQTQHTAIRIPLNQVIYIETS
                     PQKHYVILHGTNNQMTFRANLKDLEKASPSLVSCHRSYLINPNNIIRINKLKREVEMTD
                     GSICPFSRTKAKMLMDTFKRRNLQ"
     PFAM_domain     5464..5778
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1574_0079"
                     /evalue="1.90E-11"
                     /label="ctg1_1574"
                     /locus_tag="ctg1_1574"
                     /protein_end="122"
                     /protein_start="17"
                     /score="44.2"
                     /tool="antismash"
                     /translation="MVLSQELKKYNKDLSIVHTFDKPQQFIEAIDSTTSNQLFFLDIEI
                     KGEKLKGLDIAKIIREKNPYATIIFVTTHSEFMPLVFDYQVSALDYIDKSLSEIEFRKK
                     I"
     PFAM_domain     5860..6129
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1574_0080"
                     /evalue="2.40E-19"
                     /label="ctg1_1574"
                     /locus_tag="ctg1_1574"
                     /protein_end="239"
                     /protein_start="149"
                     /score="69.5"
                     /tool="antismash"
                     /translation="IRIPLNQVIYIETSPQKHYVILHGTNNQMTFRANLKDLEKASPSL
                     VSCHRSYLINPNNIIRINKLKREVEMTDGSICPFSRTKAKMLMDT"
     CDS             6150..7484
                     /locus_tag="ctg1_1575"
                     /transl_table=11
                     /translation="MIIFLFLLTVVSECFNICLFLYLINKRVSIRHFLIILFCRIAYTK
                     ICNSLSWKFLFYFNEEIFYLLLSFFISRKPYLQSKLKIFNALFPTTLNNISFRVIIFFI
                     FPLFGISVETIKVNYLIAVSSSFLTILLSFLLIKLFKESFGVIQKRRLAPLISKSIIIA
                     DIIMIAYTFTQQYLVYLENTTHTSTLIIRKLIVVIYLVLFFIMLIFLDRNIRATIQSQL
                     DFQKDIQLSHLKNYNKQIENLYQSVRSFRHDYANILTTLKLGIEQNDMAIVKEVYDSVL
                     KDSDKHLKSKTFDLTRLINIGDNTIKSLLASKFLEAEENNIDVSLDIPETIKLEGMEMV
                     DFITVISIFLDNAMEASIQSDIPKMHIGYFNHGNKQLFIVQNSTREEFISITSLFERGV
                     SSKEGNRGIGLANVRNILDNYQNISLKTESMTFAFTQELNISKKA"
     PFAM_domain     7158..7469
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1575_0081"
                     /evalue="5.20E-14"
                     /label="ctg1_1575"
                     /locus_tag="ctg1_1575"
                     /protein_end="440"
                     /protein_start="336"
                     /score="52.1"
                     /tool="antismash"
                     /translation="MEMVDFITVISIFLDNAMEASIQSDIPKMHIGYFNHGNKQLFIVQ
                     NSTREEFISITSLFERGVSSKEGNRGIGLANVRNILDNYQNISLKTESMTFAFTQELNI
                     "
     CDS             complement(7571..7972)
                     /locus_tag="ctg1_1576"
                     /transl_table=11
                     /translation="MKLKNISSRVLRFFRVVTAVLAVFLISTSISLYKSKTSPEIWLAV
                     GALALVVILVNGLLCRMLKKRPDSVNPLTIRQSFIVFLVISFLVLCVEFYTLLTFSDIT
                     DRIVLAVLMLLLILCDFLSYLQVKNYFKQ"
     CDS             complement(8098..8268)
                     /locus_tag="ctg1_1577"
                     /transl_table=11
                     /translation="MLIFDVPEVKLFLLMIAEIVLYLIAYLCNRKNKDMYIRLFKISVL
                     MTLLYYISSRI"
     CDS             complement(8302..8469)
                     /locus_tag="ctg1_1578"
                     /transl_table=11
                     /translation="MFKNSKPYLLATILIGMGLANLFRSLDAVHHTINLFGLTLLLYSL
                     LFKKWAQFKK"
     CDS             complement(8815..8940)
                     /locus_tag="ctg1_1579"
                     /transl_table=11
                     /translation="MFDLKSYILGMVFMALMTFLDKPIMSFLEKRKATNSAKKKS"
     CDS             complement(8947..9177)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1580"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.2e-16,
                     bitscore: 57.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQTMNTFETLDLETLANVEGGGCSWGGFAKQGVATGVGNGLRL
                     GIKTRTWQGAVAGAAGGAIVGGVGYGATCWW"
     PFAM_domain     complement(8983..9162)
                     /aSDomain="Bacteriocin_IIc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10439.11"
                     /description="Bacteriocin class II with double-glycine
                     leader peptide"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1580_0082"
                     /evalue="8.50E-13"
                     /label="ctg1_1580"
                     /locus_tag="ctg1_1580"
                     /protein_end="65"
                     /protein_start="5"
                     /score="48.2"
                     /tool="antismash"
                     /translation="MNTFETLDLETLANVEGGGCSWGGFAKQGVATGVGNGLRLGIKTR
                     TWQGAVAGAAGGAIV"
     CDS             complement(9338..11083)
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     286.2; E-value: 3.1e-87)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 311.7; E-value:
                     1.6e-94)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1581"
                     /transl_table=11
                     /translation="MPNQNQWSVFKRLLTYLKPYKFLTFLALAFLLSTTVIKSIIPLVA
                     SYFIDHYLHDMNQAASLILIGYYGLYLLQTLVQYLGNLFFARVSYSIVRDIRRDAFANM
                     EKLGMSYFDKTPAGSIVSRLTNDTETISEMFSGILSSFISAIFIFVTTLYTMMMLDIRL
                     TGLIVLFLPLIVLLVNLYRKKSVVIIEKTRALLSDINAKLSESIEGIRIIQAFNQEKRL
                     KKEFDAINEEHLIYASRSMSLDSLFLRPAMSLLKLLGYAVLMAYFGYRGIYLGITAGTM
                     YAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPEQRDTDAKVTEGNI
                     RFENVSFSYDGKHQILDNISFSVNKGETIAFVGSTGSGKSSIINVFMRFYEFQSGRVLL
                     DGVDIRDYSQAELRKNIGLVLQEPFLYHGTIKSNIAMYQELTDEEIKAAAEFVDANHFI
                     DKLPEGYDAPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANIDSETEAIVQNS
                     LAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIEHGSHEELLALGGTYHKMYSLQAG
                     AMEGE"
     PFAM_domain     complement(9572..10018)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1581_0084"
                     /evalue="7.40E-32"
                     /label="ctg1_1581"
                     /locus_tag="ctg1_1581"
                     /protein_end="504"
                     /protein_start="355"
                     /score="110.8"
                     /tool="antismash"
                     /translation="LDNISFSVNKGETIAFVGSTGSGKSSIINVFMRFYEFQSGRVLLD
                     GVDIRDYSQAELRKNIGLVLQEPFLYHGTIKSNIAMYQELTDEEIKAAAEFVDANHFID
                     KLPEGYDAPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATA"
     PFAM_domain     complement(10202..11011)
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1581_0083"
                     /evalue="1.10E-38"
                     /label="ctg1_1581"
                     /locus_tag="ctg1_1581"
                     /protein_end="294"
                     /protein_start="24"
                     /score="133.6"
                     /tool="antismash"
                     /translation="FLALAFLLSTTVIKSIIPLVASYFIDHYLHDMNQAASLILIGYYG
                     LYLLQTLVQYLGNLFFARVSYSIVRDIRRDAFANMEKLGMSYFDKTPAGSIVSRLTNDT
                     ETISEMFSGILSSFISAIFIFVTTLYTMMMLDIRLTGLIVLFLPLIVLLVNLYRKKSVV
                     IIEKTRALLSDINAKLSESIEGIRIIQAFNQEKRLKKEFDAINEEHLIYASRSMSLDSL
                     FLRPAMSLLKLLGYAVLMAYFGYRGIYLGITAGTMYAFIQYINRLFDP"
     CDS             complement(11076..12833)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 390.4; E-value:
                     2.3e-118)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1582"
                     /transl_table=11
                     /translation="LSFKESIIAKLWWFFKLEKRRYIVGILALSLVSVLNLIPPMVMGR
                     VIDAITSGKLTNQILLLNLVYLLLAALGMYYLRYVWRMYILATSYRLGQIMRSRLFEHF
                     TKMSPSFYQKYRTGDLMAHATNDINSLTRLAGGGVMSAVDASITALVTLITMFFSISWQ
                     MTLVAVLPLPFMAFATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQEA
                     ELQSFQETNKMTFKKNMHTMKYDSLFDPLVLLFVGSSYVLTLLVGAFMIQAGQITVGNL
                     VTFITYLDMLVWPLMAIGFLFNITQRGNVSYQRIETLLEQESDVQDPAHPLPSIENGRL
                     EYAIDRFAFEDEDTLRDVHFTLDKGQTLGLVGQTGSGKTALVKLLLREHDVNQGAIYLN
                     GHNIRDYRLSDLRSLMGYVPQDQFLFASSILDNVRFGNPDLSFDKVEEATKLAQVYDDI
                     KDMPEGFETIIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEYAIIDN
                     LKHTRKDKTTIITAHRLSAVVHADLILVMQDGRIIERGRHEDLLAQGGWYAKTYESQQL
                     EMEGGEADA"
     PFAM_domain     complement(11328..11771)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1582_0086"
                     /evalue="5.60E-28"
                     /label="ctg1_1582"
                     /locus_tag="ctg1_1582"
                     /protein_end="502"
                     /protein_start="354"
                     /score="98.3"
                     /tool="antismash"
                     /translation="LRDVHFTLDKGQTLGLVGQTGSGKTALVKLLLREHDVNQGAIYLN
                     GHNIRDYRLSDLRSLMGYVPQDQFLFASSILDNVRFGNPDLSFDKVEEATKLAQVYDDI
                     KDMPEGFETIIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDS"
     PFAM_domain     complement(11949..12767)
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1582_0085"
                     /evalue="5.60E-41"
                     /label="ctg1_1582"
                     /locus_tag="ctg1_1582"
                     /protein_end="295"
                     /protein_start="22"
                     /score="141.1"
                     /tool="antismash"
                     /translation="IVGILALSLVSVLNLIPPMVMGRVIDAITSGKLTNQILLLNLVYL
                     LLAALGMYYLRYVWRMYILATSYRLGQIMRSRLFEHFTKMSPSFYQKYRTGDLMAHATN
                     DINSLTRLAGGGVMSAVDASITALVTLITMFFSISWQMTLVAVLPLPFMAFATSRLGRK
                     THKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQEAELQSFQETNKMTFKKNMHTMKY
                     DSLFDPLVLLFVGSSYVLTLLVGAFMIQAGQITVGNLVTFITYLDMLVWPL"
     CDS             complement(12897..13292)
                     /locus_tag="ctg1_1583"
                     /transl_table=11
                     /translation="MTMVKADTYQSGRDADIMRERGQVWNYSEAKREPQLANYNTDGRY
                     LSEATNFELYNFVREYKTSDEIRRIWNPKKDESVIHDKDSYSMDDGHKVYNFDSFAYQL
                     PESTDFGKLSYIGHFQLEDGTIYRYWK"
     CDS             complement(13279..13368)
                     /locus_tag="ctg1_1584"
                     /transl_table=11
                     /translation="MNKHVWRNNETFNDDSSHRINVRSNNDDG"
     CDS             complement(13446..13973)
                     /locus_tag="ctg1_1585"
                     /transl_table=11
                     /translation="MFRLKTWVDKDGELTPKGRKLSRVLVYTYLLCLVLLCWTPQYGLV
                     EGVDTPGIQHFGRVVVLLTPFNSLTNFYQLDSLKEIVFVLGQNVTNIFLLSPLILGLLA
                     LYPRFRSWKKVLLATFVMSLTIEVGQVILDLLIDANRVFELDDLWTNTLGGLLALAAYR
                     LLVKLIQTHFKE"
     PFAM_domain     complement(13479..13892)
                     /aSDomain="VanZ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04892.14"
                     /description="VanZ like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1585_0087"
                     /evalue="4.90E-18"
                     /label="ctg1_1585"
                     /locus_tag="ctg1_1585"
                     /protein_end="165"
                     /protein_start="27"
                     /score="66.1"
                     /tool="antismash"
                     /translation="TYLLCLVLLCWTPQYGLVEGVDTPGIQHFGRVVVLLTPFNSLTNF
                     YQLDSLKEIVFVLGQNVTNIFLLSPLILGLLALYPRFRSWKKVLLATFVMSLTIEVGQV
                     ILDLLIDANRVFELDDLWTNTLGGLLALAAYRLL"
     CDS             complement(13975..15144)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1586"
                     /sec_met_domain="PF04055 (E-value: 3.3e-19, bitscore: 66.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEVTTQAKPERRKRQKLEDMEGYKPSIYGLTRDELIDWAMEHGE
                     KKFRATQIWDWLYKKRVQSFEEMTNISKDFIAKLNENFCVNPLKQRIVQESKDGTVKYL
                     FELPDGMLIETVLMRQHYGLSVCVTTQVGCNIGCTFCASGLIKKQRDLTAGEIVAQIML
                     VQKYFDDRGDGERVSHVVVMGIGEPFDNYDNVLRFLRTINNDNGLAIGARHITVSTSGL
                     APKIKEFANEGVQVNLAVSLHAPNNDLRSSIMRINRSFPLEKLFEAIEYYIQTTNRRVT
                     FEYIMLNEVNDHPENAQELADLTKKIRKLSYINLIPYNPVSEHDQYSRSTKERVAAFYD
                     VLKKNGVNCVVRQEHGTDIDAACGQLRSNTMKRDRQKAVAEASGKSEGK"
     aSDomain        complement(14026..15075)
                     /aSDomain="TIGR00048"
                     /aSTool="tigrfam"
                     /description="rRNA_mod_RlmN: 23S rRNA
                     (adenine(2503)-C(2))-methyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1586_0028"
                     /evalue="4.20E-133"
                     /identifier="TIGR00048"
                     /label="ctg1_1586"
                     /locus_tag="ctg1_1586"
                     /protein_end="373"
                     /protein_start="23"
                     /score="441.6"
                     /tool="antismash"
                     /translation="YKPSIYGLTRDELIDWAMEHGEKKFRATQIWDWLYKKRVQSFEEM
                     TNISKDFIAKLNENFCVNPLKQRIVQESKDGTVKYLFELPDGMLIETVLMRQHYGLSVC
                     VTTQVGCNIGCTFCASGLIKKQRDLTAGEIVAQIMLVQKYFDDRGDGERVSHVVVMGIG
                     EPFDNYDNVLRFLRTINNDNGLAIGARHITVSTSGLAPKIKEFANEGVQVNLAVSLHAP
                     NNDLRSSIMRINRSFPLEKLFEAIEYYIQTTNRRVTFEYIMLNEVNDHPENAQELADLT
                     KKIRKLSYINLIPYNPVSEHDQYSRSTKERVAAFYDVLKKNGVNCVVRQEHGTDIDAAC
                     GQLRSNTMKR"
     PFAM_domain     complement(14263..14763)
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1586_0088"
                     /evalue="1.40E-17"
                     /label="ctg1_1586"
                     /locus_tag="ctg1_1586"
                     /protein_end="294"
                     /protein_start="127"
                     /score="64.6"
                     /tool="antismash"
                     /translation="VTTQVGCNIGCTFCASGLIKKQRDLTAGEIVAQIMLVQKYFDDRG
                     DGERVSHVVVMGIGEPFDNYDNVLRFLRTINNDNGLAIGARHITVSTSGLAPKIKEFAN
                     EGVQVNLAVSLHAPNNDLRSSIMRINRSFPLEKLFEAIEYYIQTTNRRVTFEYIMLNEV
                     NDHP"
     CDS             complement(15148..15876)
                     /locus_tag="ctg1_1587"
                     /transl_table=11
                     /translation="MRKEILPEMFNYNKYPGPDFVYVADLLKSDACQFTVLENHKDALD
                     ATRFGQRFSEIMLKYDYIVGDWSNDQLRLKGFYEDERPNTRKTDRISRLSEYLREYCAF
                     GCAYFILKNEEPQLIVFEEETEPRRKRRRSNNRRNSSQESRDRERNTSQKNKGQKASAK
                     QKPDKSKRRDRDQEGPSFEKIKRRPKFKSRSEDGGRERKPNFKKSQKQAPKSKGQNTPS
                     KKQSQTKSDGQHFTIRKKGN"
     PFAM_domain     complement(15541..15789)
                     /aSDomain="DUF1027"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06265.13"
                     /description="Protein of unknown function (DUF1027)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1587_0089"
                     /evalue="1.10E-35"
                     /label="ctg1_1587"
                     /locus_tag="ctg1_1587"
                     /protein_end="112"
                     /protein_start="29"
                     /score="121.7"
                     /tool="antismash"
                     /translation="DACQFTVLENHKDALDATRFGQRFSEIMLKYDYIVGDWSNDQLRL
                     KGFYEDERPNTRKTDRISRLSEYLREYCAFGCAYFILK"
     CDS             complement(15931..17331)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283:2`,3`-cyclic-nucleotide 2`-phosphodiesterase
                     (Score: 208; E-value: 4.6e-63)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1588"
                     /transl_table=11
                     /translation="MIVKFFYSKSATIGVMKDTIRILHINDLHSHFEQYPQLKRAVDDL
                     SQTDRELIKVDLGDNVDKSHPLSDATAGRFNVALMNELGIDYATIGNNEGIGLAKEELD
                     CLYEQAKFQPIIGNLKDEGRQPEWAKPYLIHKTKAGTNIAFLAYTFPYYITYAPNGWQV
                     LEPMARLEEDLARPEVKDADIVVVLSHLGVRYDEQIAETYPQVNLVIGSHTHHLFEEGK
                     LVNETYLAAADRYGYYLGCIDLTVENGRLIECQIEAIPTKSYILDLDKEDETFIKAMRE
                     EGHRRLAQKKVANLGRELDFDETCQLVLQAVCQETDSQLTLLNTGLIMKTLGPQVTMAD
                     LQEALPHQMRMARLVVTGQELKEICQEVFTKAELLKNQAIKGMGFRGKTFGEVITGNFA
                     YKNGNLLYNRRVVDSNEKFSLVLVDQYYFASYFPTIKEKEVTLLFPDLLRELVDKYLGK
                     NGANWDKI"
     PFAM_domain     complement(16684..17274)
                     /aSDomain="Metallophos"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00149.30"
                     /description="Calcineurin-like phosphoesterase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1588_0090"
                     /evalue="3.20E-12"
                     /label="ctg1_1588"
                     /locus_tag="ctg1_1588"
                     /protein_end="216"
                     /protein_start="19"
                     /score="47.5"
                     /tool="antismash"
                     /translation="IRILHINDLHSHFEQYPQLKRAVDDLSQTDRELIKVDLGDNVDKS
                     HPLSDATAGRFNVALMNELGIDYATIGNNEGIGLAKEELDCLYEQAKFQPIIGNLKDEG
                     RQPEWAKPYLIHKTKAGTNIAFLAYTFPYYITYAPNGWQVLEPMARLEEDLARPEVKDA
                     DIVVVLSHLGVRYDEQIAETYPQVNLVIGSHTHH"
     CDS             complement(17560..17790)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1589"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 2.5e-08,
                     bitscore: 31.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQIINNFNSLNSEDLSTVKGGACSFWGATAAVGVGAVGGAIKG
                     GIQTGTWQGAALKGIGYGIKDGITYGLICRY"
     CDS             complement(18269..19669)
                     /gene_functions="other (smcogs) SMCOG1122:ATP-dependent RNA
                     helicase (Score: 332.8; E-value: 6.3e-101)"
                     /gene_kind="other"
                     /locus_tag="ctg1_1590"
                     /transl_table=11
                     /translation="MLFFCYNDRDRLDRKEEVNMSFKDFNFKTFIQEALDEIKFKEPTP
                     VQQKLIPVVRSGRDLVGESKTGSGKTHTFLLPIFEKLNPKSGDVQVVITAPSRELATQI
                     YQATKQIAKHSETEIRVVNYVGGTDKQRQIEKLKVAQPHIVIGTPGRIYDLVKSGDLAI
                     HKAHTFVVDEADMTMDMGFLDTVDKIAASLPKEVQILVFSATIPQKLQPFLKKYLTNPV
                     MEQIKTSTVIADTIDNWLVSTKGRNKNEQILEMLKGMQPYLAMIFVNTKERADDLHSYL
                     VSNGLKVAKIHGGIPPRERKRIMNQVKKLDFEYIVATDLAARGIDIEGVSHVINDAIPQ
                     DLSFFVHRVGRTGRNGLSGTAITLYQPSDDSDIRELEKMGITFEPKVYKDGEFQDTYDR
                     DRRANREKAYQKLDTEMIGLVKKKKKKIKPGYKKKIQWKVDEKRKRERRAANRAKGRAE
                     RKAKKQSF"
     PFAM_domain     complement(18602..18928)
                     /aSDomain="Helicase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00271.33"
                     /description="Helicase conserved C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1590_0092"
                     /evalue="2.10E-25"
                     /label="ctg1_1590"
                     /locus_tag="ctg1_1590"
                     /protein_end="356"
                     /protein_start="247"
                     /score="89.3"
                     /tool="antismash"
                     /translation="KNEQILEMLKGMQPYLAMIFVNTKERADDLHSYLVSNGLKVAKIH
                     GGIPPRERKRIMNQVKKLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGR
                     TGRNG"
     PFAM_domain     complement(19040..19540)
                     /aSDomain="DEAD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00270.31"
                     /description="DEAD/DEAH box helicase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1590_0091"
                     /evalue="9.20E-43"
                     /label="ctg1_1590"
                     /locus_tag="ctg1_1590"
                     /protein_end="210"
                     /protein_start="43"
                     /score="146.1"
                     /tool="antismash"
                     /translation="TPVQQKLIPVVRSGRDLVGESKTGSGKTHTFLLPIFEKLNPKSGD
                     VQVVITAPSRELATQIYQATKQIAKHSETEIRVVNYVGGTDKQRQIEKLKVAQPHIVIG
                     TPGRIYDLVKSGDLAIHKAHTFVVDEADMTMDMGFLDTVDKIAASLPKEVQILVFSATI
                     PQKL"
     CDS             complement(19685..20707)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1591"
                     /sec_met_domain="Glycos_transf_4 (E-value: 1.9e-39,
                     bitscore: 132.1, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMSLIAGVAAFVLTVLAMPHFITYYKIKKIGGQQMHEDVKQHLA
                     KAGTPTMGGTVFLVVAILFSLIFNFHVFSEGHQAYGATVGILFVILIYGIIGFLDDFLK
                     IFRQINEGLKPWQKMALQIIAGLLFYFIHVLPSGTDSLAIGGLTIHLGVFYVLFVLFWI
                     VGFSNAVNLTDGIDGLASISVVISLIAYGIIAFVKGEFAILTIIITMIGALLGFFVFNH
                     KPAKVFMGDVGSLSLGAMLAVISIALRVEWTLLLIGVVYVFETASVMLQVSYFKYTKRK
                     YGEGRRIFRMTPFHHHLELGGLSGKGDKWSEWKVDAFLWTVGALASAITLWMVLGNVMK
                     "
     aSDomain        complement(19712..20665)
                     /aSDomain="TIGR00445"
                     /aSTool="tigrfam"
                     /description="mraY:
                     phospho-N-acetylmuramoyl-pentapeptide-transferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1591_0029"
                     /evalue="9.00E-73"
                     /identifier="TIGR00445"
                     /label="ctg1_1591"
                     /locus_tag="ctg1_1591"
                     /protein_end="332"
                     /protein_start="14"
                     /score="243.5"
                     /tool="antismash"
                     /translation="TVLAMPHFITYYKIKKIGGQQMHEDVKQHLAKAGTPTMGGTVFLV
                     VAILFSLIFNFHVFSEGHQAYGATVGILFVILIYGIIGFLDDFLKIFRQINEGLKPWQK
                     MALQIIAGLLFYFIHVLPSGTDSLAIGGLTIHLGVFYVLFVLFWIVGFSNAVNLTDGID
                     GLASISVVISLIAYGIIAFVKGEFAILTIIITMIGALLGFFVFNHKPAKVFMGDVGSLS
                     LGAMLAVISIALRVEWTLLLIGVVYVFETASVMLQVSYFKYTKRKYGEGRRIFRMTPFH
                     HHLELGGLSGKGDKWSEWKVDAFLWTVGALASAITLW"
     PFAM_domain     complement(19964..20458)
                     /aSDomain="Glycos_transf_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00953.23"
                     /description="Glycosyl transferase family 4"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1591_0094"
                     /evalue="6.00E-38"
                     /label="ctg1_1591"
                     /locus_tag="ctg1_1591"
                     /protein_end="248"
                     /protein_start="83"
                     /score="130.5"
                     /tool="antismash"
                     /translation="VGILFVILIYGIIGFLDDFLKIFRQINEGLKPWQKMALQIIAGLL
                     FYFIHVLPSGTDSLAIGGLTIHLGVFYVLFVLFWIVGFSNAVNLTDGIDGLASISVVIS
                     LIAYGIIAFVKGEFAILTIIITMIGALLGFFVFNHKPAKVFMGDVGSLSLGAMLAVISI
                     AL"
     PFAM_domain     complement(20534..20572)
                     /aSDomain="MraY_sig1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10555.11"
                     /description="Phospho-N-acetylmuramoyl-pentapeptide-transfe
                     rase signature 1"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1591_0093"
                     /evalue="5.50E-05"
                     /label="ctg1_1591"
                     /locus_tag="ctg1_1591"
                     /protein_end="58"
                     /protein_start="45"
                     /score="22.5"
                     /tool="antismash"
                     /translation="KAGTPTMGGTVFL"
ORIGIN
        1 cagtttgaag ataataaggt tggtgaaccc aaaccacgat agcttgtcct aagaaagcac
       61 cgagaagttg agcaatcaag taacctggaa cggctaccca tgagaacaag ccagatgcag
      121 caagtccaag tgtgaaggct gggttgatgt ggttaccaga aacatcacca aacataagtg
      181 ctggcatcat taccgcaaaa ccataaccaa aaccaataac aagccatcca gacttattac
      241 ccttagtccc tttaagctca acattggcaa ccgaaccatt accaagtgca accatcaaag
      301 ctgtcccaat aaactcagta atgtacttca taatccaatc atgactgagc gcttctttta
      361 gaaaatcatt catttgtctc tttatttcct ttcacatttt acaataattt agacatctat
      421 cattttatca agtataatgt ctgatgtaaa gatatttctg aaatgtttac gtattctttt
      481 tttgaggttt taaagtatga aatttaacca gtttagttac atccctgtta atcctgaaat
      541 tgcttgtcag gaacttcgtt ctttgggctt tgaagtctct ttaaacgcta gtgccaaagc
      601 taattttgag gcttttgttc gcaagcactt ccttttcttt gaagatactg atttagcttt
      661 gaaaaattgg attgctgata cagagactga tctcctaacc ttcttccaat cagaccgacc
      721 tttgactgct gacgtctttg gtttggtggc tcttcaaatg ctaggatttg tccctaatgt
      781 ggactttaca gacagtgctg ctttcctaga ggaaatggct ttcccaatta cttttgatgg
      841 tagccttaat aacctccatc aattgctagc aacacgcaca cagtctggca ataccttaat
      901 tgatcagtta gtagctcagg atttgattcc tgtaagtaat aactacatct tctttaatgg
      961 taagagcttg gcaacatttg acactaatca gcttcaccgt gaggtggttt atgttgaaac
     1021 acctgtagat accgataaag atggccagtt agacttggtc aaagtgacta tcttacgtcc
     1081 tgatgtggac ttcccagttc cagccatgat gaccgcaagc ccttatcaac aagggactaa
     1141 tgagcctgct tcagataagc ttacccacaa gatggaaggt gatttactcg tcaaaccagc
     1201 aggtgaaatc tcccttagcc aaccagaaat caaggcccca gaggtagacc ttacgcctat
     1261 caatcctgtc acgaaggctc aggagcgttt tgctcacaca gatacctaca cgcttaacga
     1321 ttacatgttg gctcgtggtg tggcttctat ctatgtatca ggtgtcggta ccttcaattc
     1381 tgaaggcttc atgacctctg gagactatca gcaagttctg gcctataaag ctgtcattga
     1441 ctggctcaat ggtcgtgcac gcgcctttac tagccgtagc agacagcata ccatcactgc
     1501 agattgggca tctggtaagg tgactactac cggactttca tacttaggta ccatgtccaa
     1561 cgcccttgct acaactggtg tcgacggttt ggagatggtc atcgctgaag caggtatttc
     1621 ttcttggtac gactactatc gtgaaaatgg actcctcgtc agtcctggag gataccctgg
     1681 tgaagatctc gacaccttga ctgaatttac ctattctcgt gccctattag ctggagaata
     1741 cttacgccac caaaaagact accaagccta cctcaaagag ctaagcacag ccattgatcg
     1801 taagcatggg gactatagcc aattctggca tgaccgtaac tatgtgcagt tcgcagatcg
     1861 tgttaaagct actgttgtct ttacacatgg tagccaagac tggaatgtca aaccgattaa
     1921 cgtctatcaa atgttcaatg ctcttcctga cactcttgaa aaacacctct tcttccacaa
     1981 tggtgcccac gtttacatga atgcttggca gtctattgac ttccgagaaa gcatgaacgc
     2041 cttgatttgt cagaaactcc ttggtttgga gaatggctac acactgccta ctcttatctg
     2101 gcaaaacaac cagtctgaac agacctggga agtcctcgat aactttggac acaacaatgg
     2161 taaaattatt caacttggtg aagctgaagc tagcatcgct aaccattatg aagaggaaac
     2221 cttcaccaaa tatggtaaag cttaccaaag cttcaaggat gacctctttg cagacaaagc
     2281 caatgccatt accttggact ttgaactgga ccaagacatc cagattaatg gtcgtgtcca
     2341 cctagagctc aaggttaagt ctagcacaaa ccgtggtctc atttcggccc aagttctaga
     2401 aatgggtgac aagaagtatc tcgcacctat tcccgcactc aaacgcatga atttagataa
     2461 cggccgtctc ttcaaggaag aagctttacg tgaattgcca ttcaagcagg aaaaataccg
     2521 tgtcattacc aaaggacacc ttaacctgca aaatcgcaaa gatctcctta gcgttgagaa
     2581 tgtcagtcca aatgaatgga tgactatcgg tttggacttg caaccaacca tctacaaact
     2641 caacaagggc gacaaactcc gacttgttct ctataccaca gactttgagc acactattcg
     2701 tgataatagc aactatgaat tgactgtgga cctaagccaa agtcagatga cattgcctta
     2761 ttagcttttt atcacaaaaa atcccatagg atgagaactc ccatgggatt tttttagtgt
     2821 gtagaaataa acaagattta gacttcaatt tttacgattg attttaatat tatttaaaca
     2881 aatgatgtag ccaagacaat ggaataatac aaagatatgc cagtaaaaat agagcataaa
     2941 gctatcagat ttgattatcg aataaaaaag aaaaattgca actaataaaa tagagaacca
     3001 cagcgtcttc ttaacgaata aaaagtattg atgccatatc tctttatcac ccaaagtaac
     3061 tttagatttt ttacttagga aaagatgcat caagatctct actagactgc taagtactgt
     3121 taaaaccaga atcttactta gaggaatacc taaaaagaat cccatccact caataagcaa
     3181 ttgggacaaa acaatggccg taagggcacg tagatttttt gacataaaac ttaaacctca
     3241 cacttctctc aaacagaaag tttttacaat acctagaaag ttaccaaagc atagataagc
     3301 acttacagcc tcgctatctt tataagcacg tctatcataa actgcgattc taacctcgtt
     3361 cactttgttt aatgatttta agcactctag gtgtcagaaa agctagtaaa caaatatcca
     3421 aaacaatcat aacaataatg attaggcgcc attcggcatc tctcaccgtc agcaaacgat
     3481 aaataccagc taaaataata gccaaatgtg ccaagcccat accagagtaa atttgtttag
     3541 gagtaaactg tcgttcctca agtggacgat tgttcagttc tcgcttaatc aacaggggga
     3601 acacaagtaa aaagattgat agcaatgcca aaggtagcca aaataagaaa gaagaaccat
     3661 tatataataa ttctaaacca atattgccac ctatcaaacc aaaggcaaca accatgagtc
     3721 gtaaataaag taacgttcct gaacgaagtc ggttaagata aggcatcgca atctcctttc
     3781 atcacaatca cttgtccgct tggcataatc ataactagga cttaaggttc tttctctgct
     3841 cctcaacagg ttggaaaaga acctttttgc cccatcttcc ttttctcaat ggacaactca
     3901 accttaaaac caagaaatcc tccctaatga catcaatagc cataacgaat cgctagcaat
     3961 tttcgcaact ctgccattcg ctcctcgata cagggagaca aggttagctg gtcttttctg
     4021 accacttcgg atatttccag tgacatcctg cttaagatat agggagtggc tgaacgagag
     4081 tctgcaagtt ccgttcggta ggagtacagg acctgcttca aatcagcata atctggctta
     4141 tctccaatag tttcaattac ctcatcgatg atagctactg cttgttctcg tctctctttg
     4201 cctcctgcaa accatttaag tcctgtcatt aagaaaacct ccttatttct ttcaactaat
     4261 ttttcaatca catctttagt atagcacact gatagtcatt taaaagccag cgtcccaaaa
     4321 agtggctata tgtcccgagt agtaaaaaaa agactgaata tcatttttga ttcagtccat
     4381 gtcttattga aaaagcttta actaattctt tctatactgc ctatagactc caaataaaaa
     4441 gaaaaagaat cctattgatg ctaacaaaag ttgatagata tttcctgatg acaatagtac
     4501 tttgctatat aaatatatca tcgcaatagt cgaaaaaatg attaggtatt tcttcatttg
     4561 tatcacctag cttatactcc ttattttgtc aattacttac ttctctatat tatggttgat
     4621 atacttgatg ccccataaaa atagtacgaa acccaataat gaaaaaaaac ctacaaatat
     4681 agcgataact ttttgataat agaaatctgt tgtcaaaaaa cgaaggcaac taagtgtcag
     4741 taacaagaaa caagctaggg aagcttttaa ttgatttaac acagttggtt cttctcttct
     4801 tgtcattatt tttcgaatga gcaatatatc aaccacaacc actaagaggg ctgctacgat
     4861 gtagaccaat tggaatacgg atgataagtt atgaagtaat tgactaaaaa aaagtaccag
     4921 taaggatatg ctaactactt gggcaatgac aaatagcact atatcccttt ttgaaactct
     4981 atgtgtcatt gttgttctcc ttaacagcca agtaaggcta ctccacctcc aatagttgca
     5041 cctacggcga cagaggcccc acacattccc catcgttccc aattgactcg tcctccttca
     5101 acactagcaa gtgtttcaag gtcgagggtg ttaaagtttt caattgtttg agttcccatg
     5161 gcaactacct cctaaaattt ttatcgtgtg atctctcaat cacatcttca gtatagcatt
     5221 caagtgtctc tatcagagct agcgtcccaa aaagtggcta tatgtcccga atggtaaatt
     5281 catactataa atatcacatg atattttaat cttcttttca tctaattgta taactaagtc
     5341 atattatgat ataatattac atatttatga gtataaaaac aacagcatac aaaaatttgg
     5401 agggaactac aattggatat atatatctta gaggacaatc tcattcaaca aggacgactg
     5461 gagatggtat tgtctcaaga gttaaaaaaa tacaataaag acttatctat tgtacacacc
     5521 tttgataagc ctcagcaatt tatagaagcg attgattcaa caacttctaa ccagctcttt
     5581 tttcttgata tcgaaattaa gggagaaaaa ttaaaagggc tcgatattgc taaaatcatt
     5641 agggaaaaaa atccctacgc tactattatc tttgtcacta cccactcaga gtttatgcca
     5701 ctagtttttg attaccaagt atctgcccta gactatattg ataaaagtct ctctgaaata
     5761 gaatttagga aaaagataac cagagcttta gctataacta tgaaaccact tggaatagag
     5821 aatgacgaga tttttgattt tcaaacacaa catacagcta ttcgcatacc tttaaaccaa
     5881 gttatctata ttgaaacttc tccgcaaaag cattatgtga tactccatgg tacaaacaat
     5941 caaatgacct ttcgtgcaaa tctaaaggac cttgaaaaag ctagtccttc actcgtatct
     6001 tgccatcgtt cgtatctcat taaccctaac aacattataa gaatcaacaa attaaaacgt
     6061 gaagtcgaaa tgactgatgg tagtatctgt cctttttcac gtaccaaagc taaaatgctg
     6121 atggatactt ttaaaagaag gaaccttcaa tgattatttt tttatttttg cttactgttg
     6181 tctctgaatg tttcaatatt tgcctgtttc tttacttaat aaacaaaaga gtttcaatta
     6241 ggcattttct tattatctta ttttgtcgca tagcatatac caaaatatgt aacagtctat
     6301 cctggaaatt cttattctac tttaacgaag aaatattcta tcttttatta tcttttttta
     6361 tatcacgaaa gccctactta caatcaaagc ttaaaatatt caatgctctt ttccccacaa
     6421 ctcttaataa tatcagtttt agagtaatca ttttctttat atttcctttg tttggaatca
     6481 gtgttgaaac aataaaagtt aattatctta tagctgtctc atcttctttc ctaactattt
     6541 tactatcctt tcttttaata aaattattca aggaaagctt tggagttata cagaaaagac
     6601 gattagcccc tctcatatca aagagtatca ttattgctga tatcattatg attgcttata
     6661 catttaccca gcaatatctc gtctacctcg aaaacactac tcatacatcc actctgataa
     6721 tcaggaagtt aattgtggtt atttatctag tcttgttctt tatcatgctt atcttcttag
     6781 atagaaatat ccgagcaaca atacaaagtc agttggactt tcaaaaagat attcaactat
     6841 cgcatcttaa gaattataac aaacagattg aaaacctcta tcagtcggtt cgaagttttc
     6901 gtcatgatta tgccaatatt ttaacaacac tcaaacttgg tatcgaacaa aatgatatgg
     6961 ctattgtgaa agaagtctac gactcagttc taaaagattc cgataagcat ttaaaatcga
     7021 aaacatttga tttaactcgc ttaataaaca taggagataa cactattaaa agcctacttg
     7081 catctaagtt cctagaggca gaagaaaata acattgatgt ctctctagat attcctgaaa
     7141 ctatcaaact tgagggtatg gagatggtcg attttattac tgtcatatct atctttctag
     7201 acaatgcgat ggaagcatcg attcagtctg acataccaaa aatgcatatt ggctacttca
     7261 accatggtaa taaacagctc tttattgtcc aaaactcgac ccgggaagaa ttcatttcga
     7321 ttacctcact ttttgagaga ggtgtctcaa gtaaagaagg taatcgaggt ataggtttgg
     7381 ccaacgttag gaatatccta gacaactatc aaaatatttc tttaaaaact gaaagtatga
     7441 cttttgcatt tacacaggaa cttaatatat cgaaaaaagc ttgactagtt tcaagctttt
     7501 tctgttgctc catcttacta tttatgaaag tatcttctag attacctaca gaataatcaa
     7561 gcaaaatcat ttattgttta aaatagtttt tgacttgcaa gtaagataga aaatcacaga
     7621 gaattaacaa aagcattaat acggctagta ctatacggtc tgtgatatca ctgaatgtaa
     7681 gtaatgtgta aaactctaca caaagcacta gaaatgagat gaccagaaag acaatgaagg
     7741 actgccgtat tgttaacgga ttcactgaat ctggacgctt cttaagcata cggcagagca
     7801 gaccatttac caaaatgact actaaagcta gcgctccgac tgctagccaa atctctggag
     7861 aggtcttgct tttgtagaga gaaatactgg tacttataag gaaaactgct agtacagcag
     7921 tgacgaccct aaaaaatcgc aatactctcg aactaatatt ctttaacttc atgataaaac
     7981 acttaagcta tgaataacct cagtcagcct tgtaaaccga ataagctatt acattaaact
     8041 ttattccttt ctgtattttt ttatactgct gtaagatctc aagtaatccc ttagcgatta
     8101 aattctactg gagatgtaat acaatagcgt cattagcact gatattttaa ataagcgaat
     8161 atacatatct ttgttctttc tattacaaag ataagcaatc aaatataata caatttccgc
     8221 tatcattagc aagaataatt ttacttcggg aacatcaaaa ataagcattt gcaagcacct
     8281 cacgttcaaa ggagcaaaag gttacttttt aaactgtgcc cattttttaa aaagcagact
     8341 ataaagaagc aaggttagcc caaacaagtt aatggtatgg tggactgcat ccaaacttct
     8401 aaatagatta gcgaggccca ttcctatgag aatggtggcc agtaaatacg gttttgagtt
     8461 tttgaacata cttttctcct taaagtgttt ttagctatct gttcacaagc tatgaatttt
     8521 attatagatt gaaagctgac aaaaaagtag tgacataaat gtcactactt gtctgatttt
     8581 atatccttga taatcgtaca cataagaaag agaaaaagac ataacccaat aagatttagg
     8641 cattgaagtc caaaactcag tttttctccc aagttatgta aggcaacaag gatgaagccc
     8701 atagacatca ttagagacac taggcgtttt ttagtcataa gtacaaatac ctcttctttt
     8761 atatcgaaat tttcaaccac tattcacaga ctagcaattg acaaggtatc tcaattagga
     8821 tttcttttta gcggaattgg tagctttgcg tttttcaaga aatgacataa taggcttatc
     8881 caaaaaagtc atcaaggcca tgaaaaccat ccctaaaata taacttttca aatcaaacat
     8941 aatccatcac caccagcatg ttgctccata accaacaccc cctacgatag cacctccagc
     9001 tgctcctgcg acagcacctt gccaagtacg tgttttgata cctaatcgta aaccattacc
     9061 aactcctgta gctactcctt gtttagcaaa acctccccag ctacatccgc caccttcaac
     9121 gtttgcaagt gtctcgagat cgagtgtttc aaaagtgttc attgtttgtg ttgtcattct
     9181 aacaacctcc taaaatatta ttttttagct tttttctctc aagctatggt tttattatag
     9241 ggtggaagac aacaaaaaag tagtgacata aatgtcacca ctcgattttg atttttaaga
     9301 aatcttttcg aatatagaat ctatgctcta aactagctta ctctccttcc attgcacctg
     9361 cttgtaggct gtacatcttg tggtaggtgc caccgagggc taggagctcc tcatggctac
     9421 cgtgttcgat gatgcggccc ttgtctaaga catagatgca gttggcatct tggattgtcg
     9481 ataggcggtg ggcaatggca atagttgtgc gcccttgacg catttttgct agagaatttt
     9541 ggacaatagc ctctgtctcc gaatcaatat tggctgtcgc ttcatccaga atcaaaatct
     9601 taggctggct agcaacggtc ctagcaaagg ctagaagttg gcgctgtcca gttgaaaaac
     9661 ttgaacctcg ttcagaaact ggagcatcat agccttctgg aagtttgtcg ataaagtgat
     9721 tggcatccac aaactcagcg gccgctttaa tctcttcatc agttaactcc tgatacatgg
     9781 caatattgga tttgattgta ccatgataga gaaagggctc ctgaaggaca agaccaatgt
     9841 tcttacgcaa ctctgcctga ctataatcgc gaatatccac accgtcaaga agaactcggc
     9901 ctgattggaa ctcatagaaa cgcataaaca cgttgataat agaggatttt ccggaacctg
     9961 tagaaccgac aaaagcgatg gtttctcctt tattgacaga gaaggaaata ttatccaaaa
    10021 tctggtgctt gccatcatag gagaaggaga cattttcaaa gcgaatattc ccctcagtaa
    10081 ccttggcatc tgtatctctc tgctcaggtt cataggtgcg ctcgtcaatc aaggcaaaga
    10141 cccgaccggc tgagaccata gaagtttgca aggttgagaa gttttgcgtc acttcaatca
    10201 agggatcaaa gaggcgatta atgtactgga taaaggcata cattgtccct gctgtgatac
    10261 ccagatagat gccacgatag ccaaaataag ccatgagaac ggcatagccc aggagcttca
    10321 gtaaactcat ggctgggcgt agaaagagag aatcaagtga catggaacgg ctagcataaa
    10381 tcaggtgttc ctcattaata gcatcaaact cttttttgag gcgtttctct tggttaaagg
    10441 cctgaatgat gcgaattcct tcgatactct ctgacagttt ggcatttata tctgaaagca
    10501 aggctctggt cttttcaatg ataaccactg attttttgcg gtaaaggtta accaaaagga
    10561 caatcagagg aagaaagagc acaataagcc cggttagacg aatgtccaac atcatcatag
    10621 tgtaaagggt agtaacaaag ataaagatag ccgaaataaa gctagacaga atccctgaga
    10681 acatctcact aatagtctct gtatcattgg tcaagcgaga aacgatagag cctgctggag
    10741 tcttgtcaaa gtaagacata cccagttttt ccatattggc aaaggcatct cggcgaatat
    10801 ccctgacaat actgtaggac acacgcgcaa aaaagagatt tcccaaatac tgaactagtg
    10861 tctgcaagag ataaagacca tagtaaccaa tcagaattaa gcttgctgcc tgattcatat
    10921 catgaagata gtggtcgata aaataagagg ccacaagggg aataatactc ttgataaccg
    10981 ttgtggacaa gaggaaggct aaagctagaa aggtcaagaa tttgtaaggc ttgagatagg
    11041 tcaagagacg cttaaacaca gaccattggt tttgattagg catcggcttc tcctccttcc
    11101 atttctaact gttgagactc ataggtcttg gcataccaac caccctgagc tagcaaatcc
    11161 tcatgtcggc cacgttcaat gatacgacca tcctgcatga ccaggatgag atcagcgtgc
    11221 accaccgcac tcaaacgatg ggcggtaatg atagtcgtct tgtccttacg ggtatgtttg
    11281 agattgtcaa taatagcata ttctgtcttg gcgtccactg ccgatagaga gtcgtccaaa
    11341 atcaaaatgt ctggatccaa aatcatggcc cgactcatgg ccagacgttg tttttgaccg
    11401 cctgataggc tgacaccctt ttcaccaatg attgtttcaa aaccttcagg catatccttg
    11461 atgtcatcat aaacttgagc caacttagtc gcttcttcta ccttgtcaaa ggagagatca
    11521 ggattaccaa agcggacatt gtctaaaatg gaactagcaa agagaaactg gtcttgagga
    11581 acatagccca tcaagctacg caagtctgat aggcgataat ctcggatgtt atgaccattc
    11641 aaatagatgg ctccttgatt aacatcgtgc tcccgcaaga gcaacttgac aagggcggtc
    11701 tttcctgaac cagtctgccc aaccaagcca agggtttgcc ccttgtccaa ggtgaaatga
    11761 acatctctca aagtatcctc atcctcaaag gcaaagcggt caatcgcata ttctaggcga
    11821 ccattttcaa tacttgggag agggtgcgca ggatcttgaa catctgattc ctgctccaga
    11881 agagtttcaa tacgttggta ggatacattt cccctctgtg tgatattaaa gaggaaacca
    11941 atggccatca gaggccaaac cagcatgtcc aaataggtaa tgaaggttac caaatttccg
    12001 accgttatct gaccagcctg aatcataaag gcaccgacaa gaagggtcaa aacataggat
    12061 gagccaacaa agagtaagac caaaggatca aaaaggctat catacttcat ggtatgcata
    12121 ttctttttaa aggtcatctt attggtctct tggaaggact gaagctcagc ctcctggtag
    12181 ccaaaagact tggttacctt gattcctgat accgactctt gaaccttatt attaagttct
    12241 gaaaaggctg cctgggactc tccaaaagct ttatgggtct tacggcccaa acgactggtc
    12301 gcaaaagcca tgaaggggag gggtaagaca gccaccagtg tcatctgcca ggaaatgctg
    12361 aaaaacatgg tgattagggt taccaaggct gtgatagagg catccacggc tgacatgacg
    12421 cccccgccag ccaagcgggt taaagagttg atatcattgg ttgcatgggc catgaggtcc
    12481 ccagttcggt acttttgata aaaagaaggc gacatcttag taaaatgctc aaaaaggcgt
    12541 gaacgcataa tctggcctaa gcgataagaa gtcgccaaga tatacatgcg ccaaacatag
    12601 cgcaaatagt acatccccag agctgccaaa agcaaatata cgagattcag aagcaagatc
    12661 tgattggtca attttcccga tgtgatagca tcaatgaccc gccccataac cataggagga
    12721 atcagattga gaaccgaaac cagactcagt gccaaaatcc cgacaatata ccggcgtttt
    12781 tctaacttga aaaaccacca aagttttgca atgattgatt ctttaaaaga caagttactc
    12841 ctcctatcct tacaaatggt taataataga cctcgtataa gtctcgtatg ataaggttac
    12901 ttccaatagc gatagattgt gccatcttct aactgaaagt gaccaatata agataacttc
    12961 ccaaaatcag tagactctgg caattgataa gcaaaggaat caaaattata gaccttgtgc
    13021 ccatcatcca tagagtagct atccttatca tggataacgg attcatcttt cttagggttc
    13081 caaatgcgtc tgatttcatc agatgtctta tactctctga caaaattgta caattcaaag
    13141 ttagttgcct cactgagata gcgaccatcg gtgttgtagt tagctaattg aggctctctc
    13201 ttagcctcag aataattcca aacctgtcct ctttctcgca tgatatcggc atcacggcca
    13261 ctttgatagg tatctgcctt aaccatcgtc attgttactc ctaacgttaa tacggtgact
    13321 actgtcatca ttaaatgttt cattatttct ccaaacgtgt ttattcattt ttccctcttt
    13381 tgaatgtgtt gtatttgtat gatagaaaat aagtgaaacc tgagacgcgt aagctcccag
    13441 gttttttact ctttaaaatg cgtttgaatc agtttcacaa ggaggcggta ggcagctaat
    13501 gccagcaaac ctcctaaagt attggtccat aaatcatcta actcaaagac acgattagca
    13561 tcaatgagaa ggtctagaat gacttgtcca acctcaatcg tcaaagacat gacaaaggtc
    13621 gctaaaagga cctttttcca agacctgaat ctggggtaca aggctaaaag ccctaaaatc
    13681 agcggactca gtaagaaaat gttggtcaca ttttgcccaa ggacaaagac aatctcctta
    13741 agactatcca gctgataaaa gttggtcaaa ctattgaatg gggttaatag gaccacaaca
    13801 cgaccaaaat gttgaatacc aggggtgtca acaccttcaa ctagcccgta ctggggtgtc
    13861 caacacagga gcactaaaca aaggagataa gtatagacca aaactcggct tagctttctt
    13921 ccttttggtg ttagttctcc atccttatct acccaagtct taagccgaaa catcttactt
    13981 accttctgat ttaccagaag cttctgccac tgctttttga cggtcgcgtt tcatagtgtt
    14041 tgaacgcaat tgtccacaag cagcatcgat atctgtaccg tgctcttgac gaaccacaca
    14101 gttaacccca tttttcttaa gcacatcgta gaaggccgcc acacgttctt tagttgaacg
    14161 gctatattga tcgtgctctg atactgggtt atatggaatc aagttgatgt atgacaactt
    14221 acggattttc ttagtcaaat cagccaactc ttgtgcattt tcaggatggt cattgacctc
    14281 attaagcatg atatactcaa aagttacacg acggttggtt gtttggatgt aatactcgat
    14341 agcttcaaag agtttttcaa gtgggaatga gcggttgata cgcatgatgc ttgaacgaag
    14401 gtcattgtta ggcgcgtgaa gtgatacggc aaggttaact tgaacacctt cgttagcaaa
    14461 ttccttgatt tttggtgcca aaccagatgt tgatacggta atgtgacgcg ctccaatggc
    14521 aagaccatta tcattgttaa tggtacgcaa gaaacgaagc acattgtcat agttatcaaa
    14581 tggctcaccg atacccataa caaccacgtg gcttacacgt tcaccgtcgc cacgatcgtc
    14641 aaagtatttt tgtaccaaca tgatttgcgc cacaatctca ccagcagtca agtcacgttg
    14701 tttcttaatc aaaccactgg cacagaaagt acaaccgatg ttacatccaa cctgggttgt
    14761 cacacagaca gacaaaccat agtgttgacg catcaaaacc gtctcaatca acataccatc
    14821 tggcaattca aaaagatatt taacggtacc atctttagat tcttgaacga tacgttgttt
    14881 caatgggttc acacagaaat tctcattcaa tttagcaatg aaatccttag aaatgttagt
    14941 catttcttcg aaagattgca cacgcttctt gtagagccaa tcccaaattt gagtagcacg
    15001 gaatttcttt tcaccgtgtt ccatagccca atcaatcaac tcgtcacgag taagaccata
    15061 aatagaaggt ttgtagcctt ccatatcctc taacttctga cgtttacgac gttctggttt
    15121 tgcttgtgtt gttacttctg acatagttta atttcctttt tttctgattg tgaaatgctg
    15181 accatctgac ttggtctggc tttgtttctt cgatggggtg ttttgacctt tagattttgg
    15241 agcttgcttc tgactcttct tgaagttagg cttacgctca cgaccaccat cctcggatct
    15301 agatttgaac ttaggacgac gcttgatttt ctcaaagctt gggccctctt gatctctatc
    15361 tcttcgtttg gacttgtctg gcttttgctt agcagaagct ttttgtcctt tattcttttg
    15421 agaagtattg cgctctctat ctctagattc ctgagaagaa ttacgacgat tattagaacg
    15481 acggcgcttg cgacgaggct ccgtctcctc ttcaaagacg attaattgcg gctcttcatt
    15541 tttcaaaata aagtaggcgc aaccaaaggc acagtattca cgcaaatact ctgacaatcg
    15601 gctaatgcgg tctgtcttac gcgtattagg gcgctcgtcc tcgtaaaatc ccttaagacg
    15661 aagctgatca ttagaccagt ccccaacgat ataatcatac ttgagcatga tttcagaaaa
    15721 acgttgccca aagcgggtag cgtctaaagc atccttgtga ttttcaagaa ctgtaaactg
    15781 acaggcatct gatttcagaa gatcagccac atacacaaag tctggccctg gatatttatt
    15841 ataattaaac atttctggca agatttcttt acgcatgtgc catcctttct gctctctctt
    15901 attttctatc ctgatgctgt aataatgtct ctatatctta tcccaattgg caccattttt
    15961 tcctaaatac ttgtccacaa gttcccttaa caaatctgga aaaagaagag taacttcctt
    16021 ttccttaatt gtagggaaat aagaagcaaa gtagtactgg tccacaagga ccaaactaaa
    16081 cttctcattg gaatctacaa cccttctatt atacaacaaa ttaccgtttt tgtaagcaaa
    16141 attccctgtg attacttcac caaatgtctt ccctctgaat cccatacctt taatagcttg
    16201 atttttaagg agttcagcct tagtaaaaac ttcctgacag atttctttga gttcttgtcc
    16261 tgtcacgact agacgtgcca tccgcatctg gtgaggaagg gcttcttgca ggtctgccat
    16321 ggtcacttga ggacctagtg ttttcatgat aagtccagta tttaaaagcg ttaattggct
    16381 atcggtctcc tgacaaacag cctgtaaaac caattgacag gtctcatcaa aatctagttc
    16441 tcgacctaga ttagctactt ttttctgagc taaacgacga tggccttcct cacgcatagc
    16501 cttgataaag gtttcgtcct ccttgtctaa atccaagatg taggacttgg tggggatagc
    16561 ctcaatctga cattctatca atcgcccatt ttccacagta aggtcaatac agccaagata
    16621 atagccatat ctgtcagcag ctgccaaata ggtttcattg actaatttcc cctcttcaaa
    16681 aaggtgatgc gtgtggctcc cgatgacaag gtttacctgt ggataagtct ctgcaatctg
    16741 ctcatcataa cgtacaccta ggtggctaag aacgacgact atatctgcat cctttacctc
    16801 aggacgagcc aaatcctctt ccaacctagc cataggctct aacacctgcc aaccattggg
    16861 agcataggtg atgtaatatg ggaaggtata ggctaagaaa gcaatgtttg tacctgcttt
    16921 agttttgtgg ataagatagg gcttagccca ttcaggttgt ctcccctcat ccttgagatt
    16981 tcctatgatt ggctgaaact tagcctgctc ataaagacag tctagctcct ccttggccag
    17041 accaatcccc tcattatttc caatagtcgc atagtctatc cccaactcat tcatcagggc
    17101 tacattaaaa cgcccggctg tcgcatcaga taagggatgg gacttatcca cattgtcccc
    17161 aagatctacc ttgatcaact ctctatccgt ctgactcaaa tcatccacag ctcgcttgag
    17221 ttgtggatac tgttcaaaat gagagtgtaa atcattgata tgaagaattc gaatcgtgtc
    17281 tttcatgact cctattgtag cacttttgct ataaaaaaac ttgacaatca ttctgccaag
    17341 tttttacatg ctatttttca aacaggaacg tattcctagt taactttctt tttaacatat
    17401 tcttctgcga gatgatagac gtcatctgct agggatatac tgacatagat gcacacaatt
    17461 gagaaaattt ctcctctaaa gtgttgccaa gcaaagaata taagcccata aattagtagc
    17521 gcaagtacta tttggccaaa aaattgactc agtaatcgcc taataacgac aaataaggcc
    17581 ataagtaatc ccatctttaa taccataacc aatacccttt aaggctgcac cttgccaagt
    17641 acctgtttga ataccacctt taatggctcc tccaacagcc ccgacgccta cggcagctgt
    17701 agctccccaa aaactacatg ctccaccctt aacagtagaa agatcttcgg aattaagtga
    17761 gttaaaattg ttaatgattt gtgttgtcat taaaacaacc tcctttaaaa tattttttag
    17821 ccttttctca aaagctatga ttgtattata gatagaaagc caacaaaaaa gtagtgacat
    17881 aaatgtcact acctgatttt gagagttgac tcaactaata acctcagact tacacattat
    17941 tttactttaa acggaaagct tcttaaaaat ggctgtgata aaactattta aaatctgtca
    18001 tagtttcagt tcttaagaca gccaattatt ttgcgagtgt agtgagcata tactgagact
    18061 tgtcgctgtg ataatgacga ctaagacttt gtagtcataa gcgttgggaa gttttgagac
    18121 cttaggctca aaagaaaaat atatcttcaa actaaataag gtcttttgac tttccaaaaa
    18181 gtttgataat aatcaaaaaa gctgaaacac tttggtttca acctcttgaa ttttaaatta
    18241 aaatttgctt tcagctaaaa gccacggctt agaaactttg cttcttagct ttacgctcag
    18301 cacgtccctt agcacggtta gctgcacggc gttcacgttt gcgtttctcg tcaaccttcc
    18361 actgaatttt cttcttatag ccaggcttga tttttttctt tttcttctta accaaaccaa
    18421 tcatttccgt atcaagtttt tgataggctt tttcacggtt ggcacgacgg tcacggtcat
    18481 aggtatcttg aaactcgccg tccttataga ctttcggctc aaaggtaatc cccatctttt
    18541 caagctcacg aatatctgag tcgtcgcttg gttgatagag ggtgatggct gttcctgaca
    18601 agccattacg tccagtacgt cctacacggt ggacaaagaa ggacagatct tgaggaatag
    18661 cgtcattgat aacatggcta accccttcaa tatcaatccc acgcgctgca aggtcagtcg
    18721 ctacaatgta ctcaaaatca agcttcttga cttgattcat gatacgctta cgttcacgtg
    18781 gcggaatacc gccgtgaatt ttcgctactt taagaccatt tgacactagg taactgtgca
    18841 aatcatcagc acgttccttg gtattaacga aaatcattgc tagatacggc tgcatcccct
    18901 taagcatctc aagaatctgc tcattcttgt tgcgaccctt ggtagatacc aaccagttat
    18961 caatagtatc cgcaataact gttgaagttt tgatttgttc catgactgga ttggtcaaat
    19021 acttcttcaa gaatggttgc aatttttgag gaatggttgc tgagaagacc aaaatttgaa
    19081 cttccttagg cagacttgcc gcaatcttgt ctacagtatc taagaatccc atatccatgg
    19141 tcatatcagc ttcgtcaaca acaaaggtat gggccttgtg aatagccaag tctccagatt
    19201 taactaggtc atagatacgc cctggtgtcc cgataacaat atgaggttgg gctaccttga
    19261 gtttctcaat ctgacgttgc ttgtctgtac cacccacata attgaccaca cgaatttcag
    19321 tctcagagtg tttggcaatt tgttttgtcg cttggtaaat ttgtgtcgcc aattcacgtg
    19381 atggtgctgt aataacaacc tgaacatcgc cactctttgg attgagtttc tcaaaaattg
    19441 gcaagaggaa ggtatgtgtc ttccctgaac ccgtctttga ttcaccaacc aaatcacgac
    19501 ctgaacggac tacaggaatc aatttctgtt gaacaggtgt tggctcctta aacttaatct
    19561 cgtcaagagc ctcctgaata aatgttttaa aattaaaatc tttaaatgac atgtttactt
    19621 cttcttttct atctagtcta tccctatcat tataacagaa aaagagcatt tctgctcttt
    19681 tcatttattt cataacgttt ccaagaacca tccaaagggt aatggcactt gcaagtgctc
    19741 caactgtcca aaggaaagca tcaaccttcc actctgacca tttgtcaccc ttacctgaaa
    19801 gaccacccaa ctcgaggtga tggtggaatg gtgtcatacg gaaaatacga cgaccttcac
    19861 catacttacg cttagtatat ttgaaatagc tgacctgtag catgacagaa gctgtctcaa
    19921 agacataaac cacaccaatc aagagtaggg tccactctac acgtagggca atagagataa
    19981 ccgcaagcat agctccaagt gacaaggaac caacatctcc cataaagacc ttagctggct
    20041 tatggttaaa gacgaagaag ccaagaagag ccccaatcat agtgataatg atagtcaaga
    20101 tagcgaactc acccttgaca aaagcgataa tcccataggc aatcaagctg ataaccacag
    20161 agatagaagc taaaccatca ataccgtctg tcaagttcac agcattcgag aaaccgacaa
    20221 tccagaataa aacaaataga acataaaaga caccgagatg aatggttaat ccaccaatag
    20281 ctaggctatc tgtcccacta gggagtacgt ggataaagta gaaaagcaaa cccgcaataa
    20341 tctgcaaggc catcttttgc caaggtttaa gtccctcatt gatttgacgg aaaatcttaa
    20401 ggaaatcatc aaggaagccg ataattccat aaatcaaaat tacaaagaga atccctactg
    20461 tagcaccata ggcttggtgg ccctcgctaa agacgtggaa gttaaaaatc aagctaaaca
    20521 agatggcaac cactaggaag actgtccctc ccatagttgg tgttccagcc ttagccaaat
    20581 gctgcttcac atcttcatgc atttgttggc caccgatttt cttgattttg tagtaagtaa
    20641 taaagtgagg catggcgagc accgtcaaca caaaggcggc cacacctgct atcagactca
    20701 tagtcatctt agtctcctaa agtaatggta atcttcttgg ttttagacag ggcttttcct
    20761 gccgcaacac tttgtttggt aacagtccct gacttgccac ccttataagt aactttaatg
    20821 cctttccatt tggcaaaggt ttcaacgttc ttcttggtcc aaccatacat gtctggaagt
    20881 tctgtgaaat cattggtcat gataagaatc tgttcattag ccttgatatt ggctttggca
    20941 tctacagaaa ccttctcaat cttatcacca acacccagaa caatcggatg aatcaggttt
    21001 tgacgaaggg tgttagctgt atcacctgga cgcttaccga taatatcgcc agtttgatag
    21061 ctcgtttctt cagtcttttc actaccttca gaaacagaag tatctagggt gtctcccata
    21121 gacatggctt cttccaagac tgggttaacc acagtcgcaa agaaagtggt attccaagcc
    21181 tcgggctcct gaacagtcac atacatgata tattctggat catctgaagg caccatggca
    21241 acaactgagt tgagcgtttc attggaacca accttatacg ttccagtctt ctcatcggca
    21301 acttgggcag taccagactt aaccgctacg tcatagttac caaccttgat aataggtgaa
    21361 ccttcagatt tattgtaaag ggtaccgaac tctggatccg taccaacgga aatcatatag
    21421 ttacgagttt cagaggcagc ttgcttagaa actggcttac cgataacttc cttcttcgct
    21481 gtacgagctg tgccttggtt aacatcggca acttgtttga taaattgagg ttccagcatt
    21541 ataccgttat ttgaaattgc ggtaaaggct cgaagcattt ggacctgagt cactgaaatc
    21601 ccttgtccga atgatgattg agctatatta acagagtttc gagagacaac ccctgaggac
    21661 tcaccgacca tcccaaaacg ggtaggaaga ccaaatttgt aaagagataa gtagttagac
    21721 caaaccttgt ctcccatctc ttgttccagc atggtcatac caacgttact tgaataagag
    21781 aatccttgag caaatgacat ggtacgacct gttgagatac cctcattgat tgaccagtca
    21841 ttaatttcaa cgtcgtcaac cttaatacca ttagcattac tgtaggtcgc attcgggttg
    21901 aaacttccat tgttaatagc agctgacaag agcatgacct tcatggttga tccaggctca
    21961 tactgagctt cgtaaagacg gttaacccag tcatagtttt tcttagcctg tccctcaaga
    22021 gtatcagaat tataggtcgg acgttgtgtc gttgcaagaa tctcacctgt cttagcatta
    22081 acaactgtcg ctgaagcatt taccccttgc gtctgctcca taaaagtatc catctgcgtt
    22141 tctaagaagg tttggagagg cgctgacaag gttgtataga tgttcttacc atcgatagct
    22201 tccttggtaa tggtttccgt accaagaagc gtattaccgt ttttatcctt ctcatagatg
    22261 gcctcaccat ctgtcccagt caagaggcta ttaagcgaac gctccaaacc agtttgacca
    22321 attaaagaat atgagccgtc ttttttattt tctacagctt cggcacgacc aagaaactct
    22381 gacgcgaagg ttccattagg atacattcgt gacgttgttg cttcaaaggc catcccctta
    22441 attcccgcat ctttaaaggc tttttctagt tcttctttaa cagagtaggt aatccccttc
    22501 ccctttagtc caaaggaaac ctggtaagca cccttagtac gcaattgggc caaggaatca
    22561 ctcttttcaa ttcctagctt atcctttaaa atatcagcaa ccttgtcaaa ctgactatct
    22621 tggacataga gtttttcttg agtcgctgac acatagctgg tcgacacgat agcgtaaatg
    22681 gcataactgg ttgaatcctc agccaaaaca tttccatttc ggtcgtaaat cgtcccacgc
    22741 ttggcagcca ctgtggtctt agtgttataa gatttagcag cctgggtcga
//
