LOCUS       c00001_NZ_MJII..       10813 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_MJII01000001.1 Intestinimonas butyriciproducens strain 27-5-10
            unitig_0, whole genome shotgun sequence.
ACCESSION   NZ_MJII01000001
VERSION     NZ_MJII01000001
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:02:29
            Original ID  :: NZ_MJII01000001.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1871130
            Orig. end    :: 1881943
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10813
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1876130:1876943](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5813
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10813
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10813
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(856..1659)
                     /locus_tag="ctg1_1784"
                     /transl_table=11
                     /translation="MNMLVCVKQVPDTTEIKIDPVTNTLIRAGVPSILNPFDGYALEAA
                     ARIKDADPSAKIVVLSMGPEQAKAVLKESLAIAADKAYLVSDRAFGGSDTLATSYIISE
                     TIKKVEELEGKFDIIFCGKQAIDGDTAQVGPEIAEHLGLPQVTYGLEAEVDGDTVKVKK
                     EVEEGVEVIGVKMPCLLTFTKPAWDPRYPTIKRKMAANRAEIPTLTAADLPTIDLTQAG
                     LKGSPTKVKKTFVPQKKSGGVKIKEETAEDSAKKLFQLLSDASII"
     PFAM_domain     complement(1021..1593)
                     /aSDomain="ETF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01012.23"
                     /description="Electron transfer flavoprotein domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1784_0001"
                     /evalue="9.20E-48"
                     /label="ctg1_1784"
                     /locus_tag="ctg1_1784"
                     /protein_end="213"
                     /protein_start="22"
                     /score="162.6"
                     /tool="antismash"
                     /translation="NTLIRAGVPSILNPFDGYALEAAARIKDADPSAKIVVLSMGPEQA
                     KAVLKESLAIAADKAYLVSDRAFGGSDTLATSYIISETIKKVEELEGKFDIIFCGKQAI
                     DGDTAQVGPEIAEHLGLPQVTYGLEAEVDGDTVKVKKEVEEGVEVIGVKMPCLLTFTKP
                     AWDPRYPTIKRKMAANRAEIPTLTAADL"
     CDS             2024..2905
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091:glutamine-binding lipoprotein glnH (Score: 132;
                     E-value: 3.2e-40)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1785"
                     /transl_table=11
                     /translation="MLKKNRLAALLLAPCLCLSLAACSGGNSAATPAPADTEPVETIGG
                     ADGPTDILLTEEESDVAYIQDKGTLVVGITNFEPMDYRDASGEWIGFDADMAKAFAESL
                     GVEAEFVEINWDNKVLELDGKNIDCVWNGMTLTDEVKSAMSTGNAYCLNAQVVVVPAGK
                     AADYQTEESLKDLSFAVESGSAGEDEVERLGCSFTPVQTQANALLEVKAGTSDAAIIDL
                     LMAGAMIGEGTSYPDLTYTVKLNSEEYGVGFRKGSDLAEAFNTFWEAAYADGTVMTAAE
                     TYGVQESLIEPD"
     PFAM_domain     2231..2875
                     /aSDomain="SBP_bac_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00497.22"
                     /description="Bacterial extracellular solute-binding
                     proteins, family 3"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1785_0002"
                     /evalue="2.40E-39"
                     /label="ctg1_1785"
                     /locus_tag="ctg1_1785"
                     /protein_end="284"
                     /protein_start="69"
                     /score="135.2"
                     /tool="antismash"
                     /translation="LVVGITNFEPMDYRDASGEWIGFDADMAKAFAESLGVEAEFVEIN
                     WDNKVLELDGKNIDCVWNGMTLTDEVKSAMSTGNAYCLNAQVVVVPAGKAADYQTEESL
                     KDLSFAVESGSAGEDEVERLGCSFTPVQTQANALLEVKAGTSDAAIIDLLMAGAMIGEG
                     TSYPDLTYTVKLNSEEYGVGFRKGSDLAEAFNTFWEAAYADGTVMTAAETYG"
     CDS             2952..3638
                     /gene_functions="transport (smcogs) SMCOG1096:polar amino
                     acid ABC transporter, inner membrane (Score: 167.6;
                     E-value: 5.3e-51)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1786"
                     /transl_table=11
                     /translation="MFFDDPALRIVVQALNSGFLKTLQLFATTLVGAIPLGLIIAFGSM
                     SRFPPLRCLTKTMVWVIRGTPLMLQLMIIYYVPGLKGFPIWGGGEHGRFLASSVAFIFN
                     YACYFSEIYRGGIAGVPQGQYEAGQVLGMTRGQIFFRVTLLQMIKRIVPPMSNEVITLV
                     KDTSLSRIIALQEIIWMGESFLKGNQGYSGLVWPLFFTGFYYLIFNGVVTVLLGRLEKK
                     LDYFRA"
     aSDomain        2988..3296
                     /aSDomain="TIGR01726"
                     /aSTool="tigrfam"
                     /description="HEQRo_perm_3TM: amino ABC transporter,
                     permease protein, 3-TM region, His/Glu/Gln/Arg/opine
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1786_0001"
                     /evalue="5.70E-20"
                     /identifier="TIGR01726"
                     /label="ctg1_1786"
                     /locus_tag="ctg1_1786"
                     /protein_end="115"
                     /protein_start="12"
                     /score="69.7"
                     /tool="antismash"
                     /translation="QALNSGFLKTLQLFATTLVGAIPLGLIIAFGSMSRFPPLRCLTKT
                     MVWVIRGTPLMLQLMIIYYVPGLKGFPIWGGGEHGRFLASSVAFIFNYACYFSEIYRG"
     PFAM_domain     3048..3623
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1786_0003"
                     /evalue="1.30E-18"
                     /label="ctg1_1786"
                     /locus_tag="ctg1_1786"
                     /protein_end="224"
                     /protein_start="32"
                     /score="67.5"
                     /tool="antismash"
                     /translation="AIPLGLIIAFGSMSRFPPLRCLTKTMVWVIRGTPLMLQLMIIYYV
                     PGLKGFPIWGGGEHGRFLASSVAFIFNYACYFSEIYRGGIAGVPQGQYEAGQVLGMTRG
                     QIFFRVTLLQMIKRIVPPMSNEVITLVKDTSLSRIIALQEIIWMGESFLKGNQGYSGLV
                     WPLFFTGFYYLIFNGVVTVLLGRLEKKLD"
     CDS             3651..4436
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 220.2; E-value:
                     5e-67)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_1787"
                     /transl_table=11
                     /translation="MAILDVSHISKAFGNTEVLRDISFSLDPGQALAIIGSSGSGKTTL
                     LRCLNFLETPDQGRIAVRDEVLFDAGDPATRRESEIRKKRLHFGLVFQSFHLFPQYTAL
                     QNVMLASQLLAQERPDFRARKKDILADIEAAARELLHQMGLSDRADHYPHQLSGGQQQR
                     VAIARALALAPDILCFDEPTSALDPELTGEVLRVIRGLAEKHTTMVIVTHEMAFARDVA
                     DQVIFMDGGVIVEQGPPEAVIGHPREERTRQFLSRYAQN"
     PFAM_domain     3705..4202
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1787_0004"
                     /evalue="1.50E-32"
                     /label="ctg1_1787"
                     /locus_tag="ctg1_1787"
                     /protein_end="184"
                     /protein_start="18"
                     /score="113.1"
                     /tool="antismash"
                     /translation="LRDISFSLDPGQALAIIGSSGSGKTTLLRCLNFLETPDQGRIAVR
                     DEVLFDAGDPATRRESEIRKKRLHFGLVFQSFHLFPQYTALQNVMLASQLLAQERPDFR
                     ARKKDILADIEAAARELLHQMGLSDRADHYPHQLSGGQQQRVAIARALALAPDILCFDE
                     PTS"
     CDS             4619..4981
                     /locus_tag="ctg1_1788"
                     /transl_table=11
                     /translation="MPSFANPFQGNVDRKLTNAELMQALRLDIAGELEAIFLYDAHYLA
                     TDDPVAKAVLADIRDEEKVHMGELITLMRHLDPREAELFLDGESEVREQLEELGITGES
                     IPASAAGPTVGSLVEE"
     PFAM_domain     4682..4855
                     /aSDomain="COQ7"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03232.15"
                     /description="Ubiquinone biosynthesis protein COQ7"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1788_0005"
                     /evalue="3.60E-06"
                     /label="ctg1_1788"
                     /locus_tag="ctg1_1788"
                     /protein_end="79"
                     /protein_start="21"
                     /score="26.9"
                     /tool="antismash"
                     /translation="MQALRLDIAGELEAIFLYDAHYLATDDPVAKAVLADIRDEEKVHM
                     GELITLMRHLDPR"
     PFAM_domain     5001..5768
                     /aSDomain="Linocin_M18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04454.14"
                     /description="Encapsulating protein for peroxidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1789_0006"
                     /evalue="6.90E-74"
                     /label="ctg1_1789"
                     /locus_tag="ctg1_1789"
                     /protein_end="256"
                     /protein_start="0"
                     /score="248.4"
                     /tool="antismash"
                     /translation="MDYLARESAPFSPETWEKIDSTVIDNAKKHMVCRRFLNIYGPLGP
                     GASTVPVDGPNKAESLQNGLGRITGRKLVELPQLYEDFTLLWRDIEESEKLDRPLDLSA
                     AASAAQRSAKREDELILFGNKALGAEGLMTAAGSYKIKRGTWNEGEDAYKDVAHAISYL
                     SSNSKLGRYALVLSPELYLDLQRLQPNVGLLELDRISKLVGGRVYPAGPFGAGKAALVC
                     AEPQYMDLAVGVDLSVGYLELKDFNHSFRILETA"
     CDS             5001..5813
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1789"
                     /sec_met_domain="Linocin_M18 (E-value: 1.5e-79, bitscore:
                     264.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLARESAPFSPETWEKIDSTVIDNAKKHMVCRRFLNIYGPLGP
                     GASTVPVDGPNKAESLQNGLGRITGRKLVELPQLYEDFTLLWRDIEESEKLDRPLDLSA
                     AASAAQRSAKREDELILFGNKALGAEGLMTAAGSYKIKRGTWNEGEDAYKDVAHAISYL
                     SSNSKLGRYALVLSPELYLDLQRLQPNVGLLELDRISKLVGGRVYPAGPFGAGKAALVC
                     AEPQYMDLAVGVDLSVGYLELKDFNHSFRILETAALRIKDPSAIVAFE"
     CDS             complement(5999..7657)
                     /locus_tag="ctg1_1790"
                     /transl_table=11
                     /translation="MAEKLKIISLGGLNEIGKNLTVYEYGGDIIVVDVGMGFPDDDMYG
                     IDVVIPDFTYLIKNQDKIRGIFLTHGHEDHIGSIPYLLRSVNAPIYATRMTAGLVKLKL
                     EEHRLLDKTKLITCEAGEVVKAGKFSVEFIHVNHSIADAVAFAIKTPVGTCIHTGDFKI
                     DSTPIQGGMIDLARLGELGKKGVLALLCDSTNVERPGYTKSERCVGASFDALFRNCESR
                     IIVTTFASNVDRIQQVISVAAKYGRKVAVTGRSMENALRVSTELGYMNVPEGTLVDLNH
                     IKGLPKNKICIITTGSQGETMSALTRIAFSTHRQVDIQAGDRVIISASAIPGNENSIGN
                     VVNELYRKGAEVVNERVGELHVSGHACQDELRIIHALIKPKFFIPLHGEQRHLKVHAKL
                     AQEMGMDPRHIVISDIGKVIELTSNSIKLNGTVPAGKVFVDGYGVGDVGSVVLRDRKHL
                     AEDGMIVVVTSMSGENGAVVSGPDIITRGFVYVKESEGLMEELRRVAMEALERCEKTHT
                     TDWAAIKGEIKNDLSGFLYKKTKRNPMILPVIMEV"
     PFAM_domain     complement(6002..6307)
                     /aSDomain="RNase_J_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17770.3"
                     /description="Ribonuclease J C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1790_0009"
                     /evalue="5.80E-35"
                     /label="ctg1_1790"
                     /locus_tag="ctg1_1790"
                     /protein_end="552"
                     /protein_start="450"
                     /score="120.5"
                     /tool="antismash"
                     /translation="VLRDRKHLAEDGMIVVVTSMSGENGAVVSGPDIITRGFVYVKESE
                     GLMEELRRVAMEALERCEKTHTTDWAAIKGEIKNDLSGFLYKKTKRNPMILPVIMEV"
     aSDomain        complement(6008..7645)
                     /aSDomain="TIGR00649"
                     /aSTool="tigrfam"
                     /description="MG423: beta-CASP ribonuclease, RNase J
                     family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1790_0002"
                     /evalue="4.80E-190"
                     /identifier="TIGR00649"
                     /label="ctg1_1790"
                     /locus_tag="ctg1_1790"
                     /protein_end="550"
                     /protein_start="4"
                     /score="630.5"
                     /tool="antismash"
                     /translation="LKIISLGGLNEIGKNLTVYEYGGDIIVVDVGMGFPDDDMYGIDVV
                     IPDFTYLIKNQDKIRGIFLTHGHEDHIGSIPYLLRSVNAPIYATRMTAGLVKLKLEEHR
                     LLDKTKLITCEAGEVVKAGKFSVEFIHVNHSIADAVAFAIKTPVGTCIHTGDFKIDSTP
                     IQGGMIDLARLGELGKKGVLALLCDSTNVERPGYTKSERCVGASFDALFRNCESRIIVT
                     TFASNVDRIQQVISVAAKYGRKVAVTGRSMENALRVSTELGYMNVPEGTLVDLNHIKGL
                     PKNKICIITTGSQGETMSALTRIAFSTHRQVDIQAGDRVIISASAIPGNENSIGNVVNE
                     LYRKGAEVVNERVGELHVSGHACQDELRIIHALIKPKFFIPLHGEQRHLKVHAKLAQEM
                     GMDPRHIVISDIGKVIELTSNSIKLNGTVPAGKVFVDGYGVGDVGSVVLRDRKHLAEDG
                     MIVVVTSMSGENGAVVSGPDIITRGFVYVKESEGLMEELRRVAMEALERCEKTHTTDWA
                     AIKGEIKNDLSGFLYKKTKRNPMILPVIM"
     PFAM_domain     complement(6440..6601)
                     /aSDomain="RMMBL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07521.14"
                     /description="Zn-dependent metallo-hydrolase RNA
                     specificity domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1790_0008"
                     /evalue="2.50E-08"
                     /label="ctg1_1790"
                     /locus_tag="ctg1_1790"
                     /protein_end="406"
                     /protein_start="352"
                     /score="33.8"
                     /tool="antismash"
                     /translation="VNERVGELHVSGHACQDELRIIHALIKPKFFIPLHGEQRHLKVHA
                     KLAQEMGMD"
     PFAM_domain     complement(7376..7606)
                     /aSDomain="Lactamase_B"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00753.29"
                     /description="Metallo-beta-lactamase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1790_0007"
                     /evalue="7.40E-11"
                     /label="ctg1_1790"
                     /locus_tag="ctg1_1790"
                     /protein_end="94"
                     /protein_start="17"
                     /score="42.5"
                     /tool="antismash"
                     /translation="KNLTVYEYGGDIIVVDVGMGFPDDDMYGIDVVIPDFTYLIKNQDK
                     IRGIFLTHGHEDHIGSIPYLLRSVNAPIYATR"
     CDS             complement(7952..10261)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 211.7; E-value:
                     2.2e-64)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1791"
                     /transl_table=11
                     /translation="MAGGEGTRLRPITLGLPKPMVPLLGRPVMEHIIGLLKRHGITDIC
                     VTLQYMPEVVQSWFGDGAELGVRLTYFVEREPLGTAGSVKNCMSHLGEDDFLVISGDAV
                     CDLDLSAAMGFHRASRADATLVLYRHPEPLEYGLVLTDDTGRVERFIEKPGWGQVFTNT
                     VNTGIYLLTRRAMDRVPEGRACDFGKDLFPALLEEGAPLYGHIADGYWCDMGDCGAYLA
                     CTADALGGKVTMDMGLPQRGPGIWAAEELPGGITVVPPCWIGPGASIEEGSLLGPHAVV
                     GPGAFVGRRSLVQRSVLMENAKVAERCTLYGTILCRGAAAQAGAVLNEGAVLGAEGMAG
                     ENSVLMERVKVWPGRKVPKGARLTASLVSGGGTGRACFGDGGVIRGTLEEELSPELLMT
                     LGGALGAEGRLGLGYGGGECARMLARCAGCGAAAAGAAVLLHDGGCPSVGAWVAERYAL
                     PASLFVEQEGERIFLHFFDRRGLPLSRARQRKLEGALLRGEVRRASADGVGAWEHVTGT
                     ASACAADAARRARYAGASMTPVAVSVPGETPADRLLRSALEELGCVVLPRKAVGVPGFA
                     AEYGGLRLAAWDEEGTVLPPERVLALVSLIELENGGGRVALPAGAPEAVRALAAVRGGE
                     VLALDRDGLEAEEVYAALPWLRDGIFAAVRLCARLGQTGERLSTLAGRVPKFVVLRREV
                     PLRRSRGEVMQDLAEAAGAQNGEGVRIQDRGGVVWLAPLSRRAALRVAVEAATLEDAEA
                     LCREYADRVRELDRQG"
     PFAM_domain     complement(9587..10261)
                     /aSDomain="NTP_transferase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00483.25"
                     /description="Nucleotidyl transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1791_0010"
                     /evalue="1.10E-46"
                     /label="ctg1_1791"
                     /locus_tag="ctg1_1791"
                     /protein_end="225"
                     /protein_start="0"
                     /score="159.5"
                     /tool="antismash"
                     /translation="MAGGEGTRLRPITLGLPKPMVPLLGRPVMEHIIGLLKRHGITDIC
                     VTLQYMPEVVQSWFGDGAELGVRLTYFVEREPLGTAGSVKNCMSHLGEDDFLVISGDAV
                     CDLDLSAAMGFHRASRADATLVLYRHPEPLEYGLVLTDDTGRVERFIEKPGWGQVFTNT
                     VNTGIYLLTRRAMDRVPEGRACDFGKDLFPALLEEGAPLYGHIADGYWCDMGDCGAYLA
                     CTA"
ORIGIN
        1 agatgccgca ggcgatgtac agcttggggc cgacggtctt gccggtctgg cccacctgat
       61 ggctgtgggg gatccagccc gcgtcaaccg ccgcgcggga agcgcccaca gtggcgccca
      121 gcacgccggc cagagccttg atgggctcga agccctcggg gccgcccacg ccgcggccgc
      181 cggacacgat gatctccgcg ccctccaggt ccacgctctc gctgtccata tccttgatca
      241 gctccagcac ctgggtgcgg atatctttgg catccacatg gatgtcttcc ttgatgatct
      301 cggccttcgc ctcgccggcc tcgcccttct tgaatacgcc gggacggacg gtgccgatct
      361 ggggacggtg atcggggcac aggatggtgg ccatcaggtt gccgccgaaa gcgggacggg
      421 tccaggccac gttgccgctc tcggggtcga tgtccagcgc ggtgcagtcg gcggtcaggc
      481 cggtcttcag acggcaggac acgcgggggc ccaggtcacg accgttgttg gtcgcaccga
      541 tgagcatgct ggtggggccg tacttctcca ccaggctcac cagagcaatg gcgtaggcgt
      601 cggtgctgaa gtgggcgtac tcggggccct ccaccacgat caccttgtcg gcgccctggg
      661 cgctggccgc gttcacagcg gcctccacat tgttgccgat gaccacggcc accagctcgc
      721 cgccctgctt gccggccatc atccggccgg gggtcagcag ctccaggccc acgttcttcg
      781 cggtgccgtc ctcattggtc tctacaaata cccaaagatc cttggtctta gcttccattg
      841 ttatctcccc ctccctcaga taatgctggc gtcgctcagc agctggaaca gcttcttcgc
      901 ggagtcttca gcggtctctt ccttgatctt cacgccgccg ctcttcttct gcggcacgaa
      961 ggtcttcttc accttggtgg gagagccctt cagaccggcc tgcgtcaggt cgatggtggg
     1021 caggtccgct gcggtgagag tggggatctc ggcgcggttg gcagccatct tgcgcttgat
     1081 ggtgggatag cggggatccc aggcgggctt ggtgaaggtc agcaggcagg gcatcttcac
     1141 gccgatgacc tcgacgccct cttccacttc cttcttcacc ttcacggtgt cgccgtccac
     1201 ctcggcctcc aggccgtagg tcacctgggg caggcccaga tgctccgcga tctcggggcc
     1261 gacctgggcg gtgtcgccgt cgatggcctg cttgccgcag aagataatgt caaacttgcc
     1321 ttccagctcc tccaccttct tgatggtctc gctgatgatg tagctggtgg ccagggtgtc
     1381 ggaaccacca aaggcccggt cgctgaccag atacgccttg tcggccgcga tagccaggga
     1441 ctccttcagc acggccttcg cctgctcggg acccatggag agcaccacga tcttggcgga
     1501 ggggtcggca tccttgatcc gggccgcggc ttccagggca tagccgtcaa acggattcag
     1561 gatggagggg acgcctgcgc ggatcagggt attggtgacc gggtcgatct tgatttccgt
     1621 cgtatccggc acctgcttga cgcatacaag catgttcatt ggttcttttc ctcctattac
     1681 gttttttggg actgcggcat acaccgggtc ccatggcgtt tttcaagttc ttcccaacaa
     1741 atgggcgcac ttgtccaaag ccatttttcc catggaacat catataccgg gacgggccca
     1801 ttgtcaattg gaaaaccatt ggtgctacca gatttttaga aattttcctg acctcaaatc
     1861 ccactctttg gcattttata caaacttttc gttccaaatc tgggcaattc aactgtgtct
     1921 ctcccattct actttttctc tttacattgg tagtttatcg tggtactatg ttaaagtcct
     1981 cgggcgcgtc ccgacacaac ctgacaaaat ggaggatact tgtatgctga agaaaaatcg
     2041 tctcgctgcg ctgctcctgg cgccgtgtct gtgcctgtcc ctggccgcct gctccggcgg
     2101 caattcggcg gccacccccg cgcccgccga caccgagccg gtggagacca tcggcggcgc
     2161 tgacggcccc acggacatcc tgctcaccga ggaagaaagc gatgtggcct acatccagga
     2221 caagggcacg ctggtggtgg gcatcaccaa ctttgagccc atggattacc gcgatgcgtc
     2281 cggcgaatgg atcggcttcg acgccgatat ggccaaggcc tttgccgagt ccctgggcgt
     2341 ggaggcggag ttcgttgaga tcaattggga caataaggtc ctggagctcg acggcaaaaa
     2401 catcgactgc gtgtggaacg gcatgaccct caccgacgag gtgaagagcg ccatgtccac
     2461 cggcaacgca tactgcctca acgcgcaggt ggtggtggtc cccgccggca aggccgctga
     2521 ttaccagacg gaggagagcc tcaaggacct ctcctttgcc gtggagtccg ggtccgccgg
     2581 cgaggacgag gtggagcggc tgggctgcag cttcacgccc gtccagaccc aggccaacgc
     2641 gctcctggag gtcaaggccg gcacctccga cgccgccatc atcgacctgc tgatggcggg
     2701 cgccatgatc ggcgagggca ccagctaccc cgacctcacc tacaccgtca agctcaacag
     2761 tgaggaatac ggcgtgggct tccgcaaggg ttccgatctg gctgaggcct tcaacacgtt
     2821 ctgggaggcc gcctatgccg acggcaccgt gatgaccgcc gccgagacct acggcgtgca
     2881 ggagtccctg atcgaacccg actgagctcc gcccggcatc tcccccaact tcataaggtg
     2941 aggtcgattc catgtttttc gacgaccctg cgctgcgcat cgtcgtacag gcgctgaaca
     3001 gcggctttct caaaacattg cagctttttg ccaccactct ggtcggcgcc atcccgctgg
     3061 ggctcatcat cgccttcggc tccatgagcc gtttcccgcc tctgcgctgc ctgaccaaga
     3121 cgatggtgtg ggtcattcgt ggcacacccc tgatgcttca gctcatgatc atctactatg
     3181 tcccgggcct gaaggggttc cctatctggg gcggcggaga gcacggccgc ttcctggcgt
     3241 ccagcgtggc ctttatcttc aattacgcct gctacttctc cgagatctac cggggcggca
     3301 tcgcgggcgt gccccagggg cagtatgagg ccgggcaggt gctgggcatg acccgggggc
     3361 agatcttttt ccgggtcacg ctgctgcaga tgatcaagcg cattgtcccc cccatgtcca
     3421 atgaagtcat caccctggtc aaggacacct ccctctcccg catcatcgcc ctgcaggaga
     3481 tcatctggat gggcgagtcc ttcctcaagg gaaatcaggg ctactccggc ctggtgtggc
     3541 ccctgttctt cactggattc tactacctga tcttcaacgg cgtggtgacc gtgctgctgg
     3601 gccggctgga aaagaagctg gactacttcc gggcataagg aggggacgat atggcgattt
     3661 tagacgtttc acatatcagc aaggcctttg ggaataccga agtgctccgg gacatcagct
     3721 tctctctgga tcccggccag gccctggcca tcatcggctc ctccggctcc ggcaagacca
     3781 cgcttctgcg atgccttaat ttcctggaga cgccggacca ggggcgcatc gccgtccggg
     3841 acgaggtcct cttcgacgcc ggagatccgg ccacccggcg ggagagcgag atccggaaga
     3901 aacggctcca tttcggtctg gtctttcagt ccttccacct ctttccccag tacacggccc
     3961 tccagaatgt gatgctggcc agccagcttc tggcccagga gcgtccggat ttcagggccc
     4021 gcaaaaaaga catcctcgcg gacatcgagg ccgctgccag ggagctgctg catcagatgg
     4081 gcctcagcga cagggccgac cactacccgc atcagctctc aggaggccag cagcagcggg
     4141 tggccatcgc ccgggcgctg gccttggcgc cggatatcct ctgctttgac gagcccacct
     4201 cggccctgga cccagagctc accggagaag tgctcagggt catccgcggg ctggcggaaa
     4261 agcacaccac catggtcatc gtcacccacg agatggcctt cgcccgcgat gtcgccgacc
     4321 aggtcatctt tatggacggc ggcgtcattg tggagcaggg tcccccggag gcggtcatcg
     4381 ggcatccccg tgaggagcgc acccggcagt ttttgtccag gtacgcacag aattgaatca
     4441 aatggctggc cccggcatac aatgccgggg ccctttttat tctttcggct cactggtgta
     4501 tagaatcctg atggatctgg aaaaatttat tttgaaattc ccttgacaag cgcgcgcaca
     4561 tccgatatag tattcacata aataagaata attactatta ttagaaggag agacgaccat
     4621 gcctagtttt gccaatccct ttcagggtaa tgtagaccgc aagctgacca acgccgagct
     4681 catgcaggcc ctccgcttgg atattgcggg ggagctggag gccattttcc tgtacgacgc
     4741 ccactatctc gccaccgacg atccggtggc caaagccgtc ctagcggata tccgggacga
     4801 agaaaaggtc catatggggg agctcatcac tctgatgcgc cacctggacc ccagagaggc
     4861 cgagcttttc ctggacggcg agtccgaggt cagggagcag ctggaggagc tggggatcac
     4921 cggagagagc attcccgcat ccgccgccgg gcccacggtc ggcagcctgg tggaagaata
     4981 attggaaagg agtatgaatc atggactatt tagccagaga gagcgcaccc ttctcccctg
     5041 agacgtggga gaaaatcgac agtaccgtga tcgacaatgc caagaagcat atggtctgcc
     5101 gccgctttct gaacatttac ggccccctgg ggcccggcgc ctccaccgtg cctgtggacg
     5161 gccccaacaa ggcggaatcc ctgcaaaacg gcctgggccg catcaccggc cggaagctgg
     5221 tggagctgcc gcagctctat gaggacttta ccctgctatg gcgggatatt gaggagtccg
     5281 aaaagctgga ccgcccgctg gacctctccg ccgccgcctc tgccgcccag cgcagcgcca
     5341 agcgcgagga tgagctgatc ctcttcggaa acaaggcgct gggggccgag ggtcttatga
     5401 ctgccgccgg ctcttacaag atcaagcgcg gcacctggaa tgagggcgag gacgcctaca
     5461 aggatgtggc tcatgccatc tcctatctct ccagcaacag caagctgggc cgctacgccc
     5521 tggtcctcag ccccgagctc tatttggacc tccagcgcct ccagcccaat gtggggcttt
     5581 tggagctgga ccgcatctct aagctggtgg gaggccgtgt gtatcccgcc ggcccctttg
     5641 gcgccgggaa ggccgcactc gtgtgcgccg agccccagta tatggacttg gccgtgggtg
     5701 tggatctctc cgtgggttat ctggagctca aggactttaa ccacagcttc cgtatcctgg
     5761 agaccgcggc gctgcgcatc aaggacccca gcgccatcgt ggcattcgaa tgatccttcc
     5821 gtaaaaacaa gagcgcccgc gtaccatgga actggtacgc gggcgctctg atttcgctcg
     5881 cttttcttcc aaacgacatg caggaacttc ggagcgtgtc cggcccctgt ttcttggcag
     5941 gggaaagcaa ttccctgcgg cgcgctccat ccggggatgg gcgcaaaagg caagcgcctc
     6001 agacctccat gatgacaggc aggatcatcg gattgcgctt ggtttttttg taaaggaacc
     6061 cggacaggtc gtttttgatc tcgcccttga tggcggccca gtcggtggta tgggttttct
     6121 cgcaccgctc cagcgcctcc atggccacac gcctgagctc ctccatcagc ccctcggact
     6181 ctttcacgta cacaaagcca cgggtgatga tgtccgggcc ggagaccacg gctccgtttt
     6241 cgccggacat agaggtgacc accacgatca tgccgtcctc ggccagatgc ttccgatccc
     6301 ggagcaccac actgcccaca tcgcccacgc cgtatccgtc cacaaagacc tttccggcgg
     6361 ggaccgtgcc gttgagcttg atggagttgg aggtcagctc aatgaccttt ccgatatcgc
     6421 tgatgacgat gtggcggggg tccatgccca tctcctgggc cagcttggcg tggactttca
     6481 ggtgccgctg ctcaccgtgg agtgggataa agaacttggg tttgatcagc gcatggatga
     6541 tcctcagctc atcctggcag gcgtggccgg agacatggag ctcccccacc cgctcgttga
     6601 ccacttcggc ccccttgcgg tagagctcgt tgaccacgtt gccgatggaa ttttcatttc
     6661 cagggatggc ggaggcggag atgatgaccc ggtctcccgc ctggatgtcc acctgcctgt
     6721 gggtggagaa ggcgatccgg gtgagggcag acatggtctc gccctggctg ccggtggtga
     6781 tgatgcagat tttgttcttt ggaagtcctt tgatatggtt aaggtccacc agcgtcccct
     6841 ccgggacgtt catatagccc aactcggtgg agacccgcag ggcattctcc atactgcggc
     6901 ctgtaacggc caccttgcgg ccgtacttcg ccgcgacgga tatgacctgc tgaatgcggt
     6961 ccacattgga ggcgaaggtg gtaacgatga tgcgggactc gcagttgcgg aacagcgcgt
     7021 cgaaagaggc gcctacgcac cgctcgcttt tggtatagcc gggccgctcc acgttggtgg
     7081 agtcgcacag gagggccagt acgcccttct tccccagctc gcccagacgg gccagatcga
     7141 tcatgccgcc ctggatgggg gtggaatcga tcttaaagtc gccggtatgg atacaggtgc
     7201 ccaccggtgt tttgatggcg aaggccaccg cgtcggcgat ggaatggttc acatggataa
     7261 actccacact gaactttcca gcctttacca cctcaccggc ctcacaggtg atgagcttgg
     7321 tcttgtccag caggcggtgc tcctccagct tcagcttcac cagccccgcc gtcatgcggg
     7381 tggcgtagat gggggcgttg acactccgca ggagataggg gatggagccg atgtggtcct
     7441 cgtgaccatg ggtgaggaag atgcctcgga tcttgtcctg gtttttgatg agataggtaa
     7501 agtcggggat gaccacgtcg atgccgtaca tgtcgtcgtc cgggaagccc atgcccacgt
     7561 ccaccacgat gatgtccccg ccgtactcgt acacggtgag gttcttgccg atctcgttga
     7621 gaccgccaag agaaatgatc ttcagttttt ctgccataaa agtaatctta cactccttat
     7681 tttactgtac caaaatggat ggtatgtaga catcggagcg cagcaaagca cagacgtttc
     7741 ccctccgcgc tttccggccc tgcctcgccg gaaagcggga tggcggtccg ccatgctccg
     7801 ctccatgtcc aattttgcct tatatatcag tgcctaagca cataaagcca tatgagatga
     7861 cactttagta taccacaatg agatataaaa gtatacaaga attttcctct ccggcccttt
     7921 gtgagggcgg agtgggggca ttccttcccg cctatccctg tcggtccagc tcgcgcaccc
     7981 ggtcggcata ctctctgcac agcgcctcgg catcctccag tgtggcggcc tccaccgcta
     8041 cccggagcgc agcccggcgg ctgaggggcg ccagccacac cacgcctccc cggtcctgga
     8101 tgcgcacccc ctccccgttc tgcgcccccg cagcctcagc caggtcctgc atgacctctc
     8161 cccggctccg ccggaggggc acctcccggc ggagaaccac aaatttgggg acccgccccg
     8221 ccagcgtgga gagccgttcc cccgtctggc ccagacgggc acacagccgg actgcggcga
     8281 agatcccgtc ccgcagccag ggaagggcgg catagacctc ctccgcttcc aaaccgtccc
     8341 ggtccagggc caggacctcc ccgccgcgta cggcggccag cgcccgcacc gcctccggcg
     8401 cccccgccgg gagcgccacg cggcctccgc cgttctccag ctcgatgagg ctgaccaggg
     8461 ccaggacccg ctccggcggg aggaccgttc cctcctcatc ccatgccgcc agccggaggc
     8521 cgccatactc cgcggcaaag ccgggcaccc ccacggcctt ccggggcagc accacgcagc
     8581 ccagctcctc cagcgccgag cggaggagcc ggtcggccgg cgtctcccca ggcacggaga
     8641 ccgccaccgg cgtcatggag gccccggcat accgggctct gcgagccgcg tcggcggcgc
     8701 aggcggaggc cgtccccgtc acatgttccc aggctcccac tccgtcggcg gacgcacggc
     8761 ggacctcgcc ccggagaagg gcgccctcca gcttgcgctg ccgggcccgg gagagaggca
     8821 gcccccgccg gtcgaaaaag tggagaaaga ttctctcccc ctcctgttcc acaaagaggg
     8881 aggcgggaag agcgtaccgc tccgccaccc aggcccccac cgagggacat ccgccgtcgt
     8941 ggaggagtac cgccgcgccc gccgccgccg cgccgcatcc ggcgcagcgg gccagcatcc
     9001 gggcacactc gccccctccg tatcccagtc ccagcctgcc ctcggctccc aaggccccgc
     9061 ccagggtcat cagcagctcc ggactcagtt cctcctccag cgtgccccgt atcacgccgc
     9121 cgtctccaaa acaggcgcgc cccgtcccgc cgccgctgac cagagaggcc gtgagccgtg
     9181 cccccttcgg gacctttctc cccggccaga ccttgacccg ttccatgagg acgctgttct
     9241 cccccgccat gccctcggct cccagcaccg cgccctcgtt gaggacggct ccggcctgtg
     9301 ccgcggcacc gcggcacagg atggtgccgt acagcgtgca gcgttccgcg actttggcat
     9361 tttccatcag gacactgcgc tggaccagac tcctccggcc gacgaaggct cccggcccta
     9421 ccacggcatg ggggcccagg aggctcccct cttcaataga ggcccccggc ccgatccagc
     9481 agggcggcac caccgtgatc ccaccgggca gctcctccgc cgcccagatg ccggggcccc
     9541 gctggggaag tcccatatcc atcgtcacct tgccccccag cgcgtcggcg gtacaggcca
     9601 gataggcgcc gcagtccccc atatcgcacc aatagccatc cgctatgtgc ccatataggg
     9661 gagcgccctc ctccagaagc gccggaaaaa gatccttgcc gaagtcgcag gcccgccctt
     9721 ccggcacacg gtccatggcc cgccgggtaa gcaggtatat ccccgtgttc actgtgttgg
     9781 taaagacttg gccccagccg ggcttttcaa tgaaccgctc cacccgtccg gtatcgtcag
     9841 taaggaccag gccgtattcc agcggctccg ggtggcggta gaggaccagt gtggcgtcgg
     9901 cacggctggc ccggtgaaag cccatggctg ccgacaggtc cagatcgcac acggcatccc
     9961 cgctgatcac caggaagtcg tcttccccca ggtgggacat gcagtttttt acactgcccg
    10021 ccgtgcccaa gggttcccgc tccacaaaat aggtcaggcg cacccccagc tccgcgccgt
    10081 ctccaaacca gctctgcacc acctcgggca tgtattggag ggtgacgcag atatccgtga
    10141 tcccatggcg cttgagcagg ccgatgatat gctccatgac cggcctgccc agaaggggca
    10201 ccatgggctt ggggagcccc agggtaatgg ggcgcagacg ggtgccctcg cctcccgcca
    10261 taatgactgc tttcacagga aaaccatcct ctctcttaaa aggcgatttt ccctagtatt
    10321 gccctccggg acaaaattaa cacacgaaag ccctctgtgc tgtgcttcct gacctgcgcc
    10381 cctttggagc agatcccacg gggccgcatt tctgcgtcat ggcggaaggc accgcaaatc
    10441 tttagtccta atacgacttt tttgaacagt cgtattagga gtattgtatg gtataaaggg
    10501 aggggatatc tcatgttcac acgtctgcga gatttgcggg aggaccatga tctcaagcag
    10561 gagaccctgg cggcggaact cgggatccgg caaacgacct attccaaata tgagctcggc
    10621 aagattgccg tccccgcttc cgcgctgatc cgaattgcgg acttttacca cgtcagcctg
    10681 gactatctgg tgggccgtga tgccgggcct gccaaggccg agcccgtcag gcccggcctg
    10741 taccgccatt tcaagggcaa ggaataccgg gtgctctaca acgccgccca ttccgagacg
    10801 ctggagccgc tgg
//
