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Overview
1.1
1.2
1.3
1.4

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP022046.2

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | cyclic-lactone-autoinducer | 655,974 | 676,686 |
Region 1.2 | RiPP-like | 1,829,799 | 1,840,092 |
Region 1.3 | terpene | 2,631,745 | 2,652,620 |
Region 1.4 | siderophore,T3PKS | 2,722,673 | 2,764,040 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | cyclic-lactone-autoinducer | 655,974 | 676,686 |
Region 1.2 | RiPP-like | 1,829,799 | 1,840,092 |
Region 1.3 | terpene | 2,631,745 | 2,652,620 |
Region 1.4 | siderophore,T3PKS | 2,722,673 | 2,764,040 |

No secondary metabolite regions were found in these records:
  NZ_CP022047.2

Compact view
NZ_CP022046.2 - Region 1 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 655,974 - 676,686 nt. (total: 20,713 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000488.1 |  | 0.18 | RiPP | circularin A | Clostridium beijerinckii
BGC0000554.1 |  | 0.16 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000500.1 |  | 0.16 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0001862.1 |  | 0.16 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.16 | RiPP | pallidocin | Aeribacillus pallidus
BGC0000504.1 |  | 0.16 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000560.1 |  | 0.16 | RiPP | subtilomycin | Bacillus subtilis
BGC0000543.1 |  | 0.16 | RiPP | pep5 | Staphylococcus epidermidis
BGC0000522.1 |  | 0.16 | RiPP | lacticin Z | Lactococcus lactis
BGC0000509.1 |  | 0.16 | RiPP | epilancin 15x | Staphylococcus epidermidis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000488.1 |  | 0.50 | RiPP | circularin A | Clostridium beijerinckii
BGC0000554.1 |  | 0.47 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000500.1 |  | 0.47 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0001862.1 |  | 0.47 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.47 | RiPP | pallidocin | Aeribacillus pallidus
BGC0000504.1 |  | 0.47 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000560.1 |  | 0.47 | RiPP | subtilomycin | Bacillus subtilis
BGC0000543.1 |  | 0.47 | RiPP | pep5 | Staphylococcus epidermidis
BGC0000522.1 |  | 0.47 | RiPP | lacticin Z | Lactococcus lactis
BGC0000509.1 |  | 0.47 | RiPP | epilancin 15x | Staphylococcus epidermidis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP022046.2 - Region 2 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,829,799 - 1,840,092 nt. (total: 10,294 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000504.1 |  | 0.16 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000548.1 |  | 0.16 | RiPP | salivaricin A | Streptococcus salivarius
BGC0000500.1 |  | 0.16 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000554.1 |  | 0.16 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001639.1 |  | 0.15 | RiPP | klebsidin | Klebsiella pneumoniae
BGC0001120.1 |  | 0.15 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000590.1 |  | 0.15 | RiPP | microcin N | Escherichia coli
BGC0000294.1 |  | 0.14 | NRP | acinetobactin | Acinetobacter baumannii
BGC0000623.1 |  | 0.14 | RiPP | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0000588.1 |  | 0.14 | RiPP | microcin L | Escherichia coli

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000504.1 |  | 0.47 | RiPP | cytolysin ClyLl, cytolysin ClyLs | Plasmid pAD1
BGC0000548.1 |  | 0.47 | RiPP | salivaricin A | Streptococcus salivarius
BGC0000500.1 |  | 0.47 | RiPP | carnolysin A1, carnolysin A2 | Carnobacterium maltaromaticum
BGC0000554.1 |  | 0.46 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001639.1 |  | 0.45 | RiPP | klebsidin | Klebsiella pneumoniae
BGC0001120.1 |  | 0.45 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000590.1 |  | 0.44 | RiPP | microcin N | Escherichia coli
BGC0000294.1 |  | 0.44 | NRP | acinetobactin | Acinetobacter baumannii
BGC0000623.1 |  | 0.44 | RiPP | plantaricin W α, plantaricin W β | Lactobacillus plantarum
BGC0000588.1 |  | 0.44 | RiPP | microcin L | Escherichia coli

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP022046.2 - Region 3 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,631,745 - 2,652,620 nt. (total: 20,876 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.32 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000648.1 |  | 0.23 | Terpene | carotenoid | Myxococcus xanthus
BGC0000646.1 |  | 0.21 | Terpene | β-carotein | uncultured bacterium
BGC0000645.1 |  | 0.21 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0001227.1 |  | 0.20 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000664.1 |  | 0.20 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.1 |  | 0.20 | Terpene | carotenoid | Streptomyces avermitilis
BGC0001456.1 |  | 0.19 | Terpene | isorenieratene | Streptomyces argillaceus
BGC0000656.1 |  | 0.18 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000663.1 |  | 0.13 | Terpene | hopene | Streptomyces coelicolor A3(2)

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000647.1 |  | 0.66 | Terpene | carotenoid | Rhodobacter sphaeroides
BGC0000648.1 |  | 0.56 | Terpene | carotenoid | Myxococcus xanthus
BGC0000646.1 |  | 0.54 | Terpene | β-carotein | uncultured bacterium
BGC0000645.1 |  | 0.54 | Terpene | carotenoid | Halobacillus halophilus DSM 2266
BGC0001227.1 |  | 0.53 | Terpene | isorenieratene | Streptomyces collinus Tu 365
BGC0000664.1 |  | 0.52 | Terpene | isorenieratene | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.1 |  | 0.52 | Terpene | carotenoid | Streptomyces avermitilis
BGC0001456.1 |  | 0.51 | Terpene | isorenieratene | Streptomyces argillaceus
BGC0000656.1 |  | 0.50 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000663.1 |  | 0.41 | Terpene | hopene | Streptomyces coelicolor A3(2)

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP022046.2 - Region 4 - T3PKS,siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,722,673 - 2,764,040 nt. (total: 41,368 nt) Show pHMM detection rules used
Region on contig edge.
siderophore: IucA_IucC
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0000944.1 |  |  | 0.43 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000946.1 |  |  | 0.35 | Other | vibrioferrin | Vibrio parahaemolyticus
BGC0000947.1 |  |  | 0.30 | Other | vibrioferrin | Vibrio alginolyticus
BGC0001870.1 |  |  | 0.29 | Other | putrebactin, avaroferrin | Xenorhabdus budapestensis
BGC0000286.1 |  |  | 0.22 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0000205.1 |  |  | 0.21 | Polyketide | bryostatin | Candidatus Endobugula sertula
BGC0000219.1 |  |  | 0.20 | Polyketide, Saccharide | elloramycin | Streptomyces olivaceus
BGC0000255.1 |  |  | 0.19 | Polyketide | pederin | Uncultured bacterium
BGC0000934.1 |  |  | 0.19 | Other (Phenazine) | 5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G | Kitasatospora sp. HKI 714
BGC0001197.1 |  |  | 0.19 | Polyketide | frankiamicin | Frankia sp. EAN1pec

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000946.1 |  | 0.68 | Other | vibrioferrin | Vibrio parahaemolyticus
BGC0000947.1 |  | 0.67 | Other | vibrioferrin | Vibrio alginolyticus
BGC0001870.1 |  | 0.66 | Other | putrebactin, avaroferrin | Xenorhabdus budapestensis
BGC0000286.1 |  | 0.55 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0000944.1 |  | 0.54 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000205.1 |  | 0.54 | Polyketide | bryostatin | Candidatus Endobugula sertula
BGC0000255.1 |  | 0.52 | Polyketide | pederin | Uncultured bacterium
BGC0000934.1 |  | 0.51 | Other (Phenazine) | 5-acetyl-5,10-dihydrophenazine-1-carboxylic acid, 5-(2-hydroxyacetyl)-5,10-dihydrophenazine-1-carboxylic acid, endophenazine A1, endophenazine F, endophenazine G | Kitasatospora sp. HKI 714
BGC0001197.1 |  | 0.51 | Polyketide | frankiamicin | Frankia sp. EAN1pec
BGC0000836.1 |  | 0.50 | Other | APE Ec | Escherichia coli CFT073

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names