GCF_902859965.1_LMG_26854_genomic - 12 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

c00001_NZ_CADI.. (original name was: NZ_CADIKO010000001.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	resorcinol	1,767,968	1,809,890	4-formylaminooxyvinylglycine	Other	14%

c00002_NZ_CADI.. (original name was: NZ_CADIKO010000002.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 2.1	NRPS	1	27,549	crochelin A	NRP + Polyketide	26%
Region 2.2	betalactone	354,247	381,817	lysobactin	NRP	4%
Region 2.3	siderophore	514,113	525,969	desferrioxamine E	Other	50%
Region 2.4	terpene	1,598,767	1,620,462

c00003_NZ_CADI.. (original name was: NZ_CADIKO010000003.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	betalactone	397,576	420,604
Region 3.2	NAPAA	1,028,996	1,062,979

c00004_NZ_CADI.. (original name was: NZ_CADIKO010000004.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	phosphonate	598,720	638,860	salecan	Saccharide	10%

c00005_NZ_CADI.. (original name was: NZ_CADIKO010000005.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	arylpolyene	34,469	78,071	APE Vf	Other	35%

c00007_NZ_CADI.. (original name was: NZ_CADIKO010000007.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 7.1	ectoine	92,169	102,573	ectoine	Other	66%

c00009_NZ_CADI.. (original name was: NZ_CADIKO010000009.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 9.1	NRPS	56,568	88,886	crochelin A	NRP + Polyketide	30%

c00011_NZ_CADI.. (original name was: NZ_CADIKO010000011.1)

Region	Type	From	To	Most similar known cluster		Similarity
Region 11.1	NRPS	1	3,024	delftibactin A / delftibactin B	NRP + Polyketide	42%

No secondary metabolite regions were found in these records:: c00006_NZ_CADI.. (original name was: NZ_CADIKO010000006.1); c00008_NZ_CADI.. (original name was: NZ_CADIKO010000008.1); c00010_NZ_CADI.. (original name was: NZ_CADIKO010000010.1); c00012_NZ_CADI.. (original name was: NZ_CADIKO010000012.1); c00013_NZ_CADI.. (original name was: NZ_CADIKO010000013.1)

Compact view

c00001_NZ_CADI.. - Region 1 - resorcinol

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Location: 1,767,968 - 1,809,890 nt. (total: 41,923 nt) Show pHMM detection rules used

resorcinol: DarB

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KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000858.1	0.23	Other	ectoine	Methylobacter marinus
BGC0000853.1	0.23	Other	ectoine	Streptomyces anulatus
BGC0000857.1	0.23	Other	ectoine	Methylophaga alcalica
BGC0000860.1	0.23	Other	ectoine	Methylarcula marina
BGC0000854.1	0.23	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000855.1	0.23	Other	ectoine	Methylomicrobium kenyense
BGC0000859.1	0.23	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000852.1	0.23	Other	ectoine	Sporosarcina pasteurii
BGC0000856.1	0.23	Other	ectoine	Methylophaga thalassica
BGC0000841.1	0.21	Other (Non-NRP beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate, clavulanic acid	Streptomyces clavuligerus ATCC 27064

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000858.1	0.57	Other	ectoine	Methylobacter marinus
BGC0000853.1	0.56	Other	ectoine	Streptomyces anulatus
BGC0000857.1	0.56	Other	ectoine	Methylophaga alcalica
BGC0000860.1	0.56	Other	ectoine	Methylarcula marina
BGC0000854.1	0.56	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000855.1	0.56	Other	ectoine	Methylomicrobium kenyense
BGC0000859.1	0.56	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000852.1	0.56	Other	ectoine	Sporosarcina pasteurii
BGC0000856.1	0.56	Other	ectoine	Methylophaga thalassica
BGC0000841.1	0.54	Other (Non-NRP beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate, clavulanic acid	Streptomyces clavuligerus ATCC 27064

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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c00002_NZ_CADI.. - Region 1 - NRPS

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Location: 1 - 27,549 nt. (total: 27,549 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.33	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001132.1	0.30	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.30	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000417.1	0.29	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0001128.1	0.29	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001149.1	0.28	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001758.1	0.27	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001131.1	0.26	NRP	ambactin	Xenorhabdus miraniensis
BGC0001825.1	0.26	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001135.1	0.26	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001615.1	0.67	NRP	hexose-palythine-serine, hexose-shinorine	Heteroscytonema crispum UCFS10
BGC0001132.1	0.63	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.1	0.63	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000417.1	0.63	NRP	rhodochelin	Rhodococcus jostii RHA1
BGC0001128.1	0.62	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001149.1	0.61	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0001758.1	0.61	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001131.1	0.60	NRP	ambactin	Xenorhabdus miraniensis
BGC0001825.1	0.60	NRP	xenematide	Xenorhabdus nematophila AN6/1
BGC0001135.1	0.60	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 27549:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg2_1

Search NORINE for peptide: strict or relaxed

AMP-binding (580..986): X

NRPSPredictor2: glu, gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DgeDhGtVtK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 50% (weak)

AMP-binding (1666..2063): X

NRPSPredictor2: glu, gln

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DvWNIGliHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 70% (weak)

c00002_NZ_CADI.. - Region 2 - betalactone

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Location: 354,247 - 381,817 nt. (total: 27,571 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000908.1	0.17	Other	melanin	Streptomyces avermitilis
BGC0001521.1	0.17	NRP	auriculamide	Herpetosiphon aurantiacus DSM 785
BGC0000829.1	0.16	Alkaloid	violacein	Chromobacterium violaceum
BGC0001733.1	0.16	RiPP	PcpA	Pleurocapsa sp. PCC 7327
BGC0000466.1	0.15	NRP	yatakemycin	Streptomyces sp. TP-A2060
BGC0001225.1	0.14	NRP	celesticetin	Streptomyces caelestis
BGC0000294.1	0.14	NRP	acinetobactin	Acinetobacter baumannii
BGC0000442.1	0.14	NRP	terrequinone A	Aspergillus nidulans FGSC A4
BGC0002009.1	0.14	Polyketide	kanglemycin A, kanglemycin V1, kanglemycin V2	Amycolatopsis vancoresmycina
BGC0001641.1	0.14	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000908.1	0.48	Other	melanin	Streptomyces avermitilis
BGC0001521.1	0.48	NRP	auriculamide	Herpetosiphon aurantiacus DSM 785
BGC0000829.1	0.47	Alkaloid	violacein	Chromobacterium violaceum
BGC0001733.1	0.46	RiPP	PcpA	Pleurocapsa sp. PCC 7327
BGC0000466.1	0.45	NRP	yatakemycin	Streptomyces sp. TP-A2060
BGC0001225.1	0.44	NRP	celesticetin	Streptomyces caelestis
BGC0000294.1	0.44	NRP	acinetobactin	Acinetobacter baumannii
BGC0000442.1	0.43	NRP	terrequinone A	Aspergillus nidulans FGSC A4
BGC0002009.1	0.43	Polyketide	kanglemycin A, kanglemycin V1, kanglemycin V2	Amycolatopsis vancoresmycina
BGC0001641.1	0.43	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1

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c00002_NZ_CADI.. - Region 3 - siderophore

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Location: 514,113 - 525,969 nt. (total: 11,857 nt) Show pHMM detection rules used

siderophore: IucA_IucC

Legend:

core biosynthetic genes

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001478.1	0.36	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.1	0.32	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001572.1	0.30	Other	desferrioxamine E	Pantoea agglomerans
BGC0001453.1	0.23	Other	desferrioxamine	Streptomyces argillaceus
BGC0000940.1	0.23	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001713.1	0.21	Other	ochrobactin	Ochrobactrum anthropi
BGC0000295.1	0.20	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001499.1	0.20	Other	aerobactin	Pantoea ananatis
BGC0001498.1	0.19	Other	aerobactin	Xenorhabdus szentirmaii DSM 16338
BGC0000939.1	0.18	Other	aerobactin	Grimontia hollisae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001478.1	0.69	Other	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.1	0.65	Other	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001572.1	0.63	Other	desferrioxamine E	Pantoea agglomerans
BGC0001453.1	0.56	Other	desferrioxamine	Streptomyces argillaceus
BGC0000940.1	0.56	Other	desferrioxamin B, desferrioxamine E	Streptomyces coelicolor A3(2)
BGC0001713.1	0.54	Other	ochrobactin	Ochrobactrum anthropi
BGC0000295.1	0.53	NRP	acinetoferrin	Acinetobacter haemolyticus
BGC0001499.1	0.53	Other	aerobactin	Pantoea ananatis
BGC0001498.1	0.51	Other	aerobactin	Xenorhabdus szentirmaii DSM 16338
BGC0000939.1	0.49	Other	aerobactin	Grimontia hollisae

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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c00002_NZ_CADI.. - Region 4 - terpene

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Location: 1,598,767 - 1,620,462 nt. (total: 21,696 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000647.1	0.33	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000640.1	0.24	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000630.1	0.23	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000656.1	0.23	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000646.1	0.21	Terpene	β-carotein	uncultured bacterium
BGC0000633.1	0.21	Terpene	carotenoid	Streptomyces avermitilis
BGC0000664.1	0.20	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000634.1	0.20	Terpene	carotenoid	Brevundimonas sp. SD212
BGC0000643.1	0.20	Terpene	carotenoid	Brevundimonas vesicularis
BGC0001456.1	0.19	Terpene	isorenieratene	Streptomyces argillaceus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000647.1	0.66	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000640.1	0.58	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000630.1	0.57	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000656.1	0.56	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000646.1	0.54	Terpene	β-carotein	uncultured bacterium
BGC0000633.1	0.53	Terpene	carotenoid	Streptomyces avermitilis
BGC0000664.1	0.53	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000634.1	0.52	Terpene	carotenoid	Brevundimonas sp. SD212
BGC0000643.1	0.52	Terpene	carotenoid	Brevundimonas vesicularis
BGC0001456.1	0.52	Terpene	isorenieratene	Streptomyces argillaceus

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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c00003_NZ_CADI.. - Region 1 - betalactone

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Location: 397,576 - 420,604 nt. (total: 23,029 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000260.1	0.18	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396
BGC0001203.1	0.17	NRP, Polyketide	clarexpoxcin	uncultured bacterium AR_456
BGC0001895.1	0.17	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0000906.1	0.16	Other	heme D1	Heliophilum fasciatum
BGC0001983.1	0.16	Other	triacsins	Kitasatospora aureofaciens
BGC0001343.1	0.16	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001687.1	0.15	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSL12
BGC0001458.1	0.15	Other (Aminocoumarin)	salinipostin G	Salinispora tropica CNB-440
BGC0000220.1	0.15	Polyketide	enterocin	Streptomyces maritimus
BGC0000805.1	0.14	Saccharide	moenomycin	Streptomyces viridosporus ATCC 14672

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000260.1	0.50	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396
BGC0001203.1	0.48	NRP, Polyketide	clarexpoxcin	uncultured bacterium AR_456
BGC0001895.1	0.48	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001
BGC0000906.1	0.47	Other	heme D1	Heliophilum fasciatum
BGC0001983.1	0.47	Other	triacsins	Kitasatospora aureofaciens
BGC0001343.1	0.46	Polyketide	aurachin A, aurachin D	Stigmatella aurantiaca Sg a15
BGC0001687.1	0.46	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSL12
BGC0001458.1	0.45	Other (Aminocoumarin)	salinipostin G	Salinispora tropica CNB-440
BGC0000220.1	0.45	Polyketide	enterocin	Streptomyces maritimus
BGC0000805.1	0.44	Saccharide	moenomycin	Streptomyces viridosporus ATCC 14672

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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c00003_NZ_CADI.. - Region 2 - NAPAA

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Location: 1,028,996 - 1,062,979 nt. (total: 33,984 nt) Show pHMM detection rules used

NAPAA: (AMP-binding and PP-binding and TIGR02353)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001184.1	0.28	Other	bacilysin	Bacillus velezensis FZB42
BGC0000888.1	0.28	Other	bacilysin	Bacillus sp. CS93
BGC0000375.1	0.22	NRP	indigoidine	Streptomyces chromofuscus
BGC0000427.1	0.21	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000231.1	0.21	Polyketide	griseusin	Streptomyces griseus
BGC0001399.1	0.21	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000679.1	0.20	Terpene	diazepinomicin	Micromonospora sp. M42
BGC0000244.1	0.19	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0001135.1	0.18	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001844.1	0.18	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001184.1	0.62	Other	bacilysin	Bacillus velezensis FZB42
BGC0000888.1	0.62	Other	bacilysin	Bacillus sp. CS93
BGC0000375.1	0.55	NRP	indigoidine	Streptomyces chromofuscus
BGC0000427.1	0.54	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0000231.1	0.54	Polyketide	griseusin	Streptomyces griseus
BGC0001399.1	0.54	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000679.1	0.52	Terpene	diazepinomicin	Micromonospora sp. M42
BGC0000244.1	0.50	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0001135.1	0.50	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001844.1	0.50	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters

No matches found.

Module view

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Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 1028995 - 1062979:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg3_942

Search NORINE for peptide: strict or relaxed

AMP-binding (21..406): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DmEHNgTVSK
Nearest Stachelhaus code:: dab
Stachelhaus code match:: 80% (moderate)

c00004_NZ_CADI.. - Region 1 - phosphonate

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Location: 598,720 - 638,860 nt. (total: 40,141 nt) Show pHMM detection rules used

Region on contig edge.

phosphonate: phosphonates

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000904.1	0.24	Other	FR-900098	Streptomyces rubellomurinus
BGC0000937.1	0.23	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0001739.1	0.21	Other	phosphonoacetic Acid	Streptomyces sp. NRRL F-525
BGC0002036.1	0.20	Other	dehydrofosmidomycin	Streptomyces lavendulae
BGC0001483.1	0.17	Other	5-isoprenylindole-3-carboxylate β-D-glycosyl ester	Streptomyces sp. RM-5-8
BGC0001538.1	0.17	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001591.1	0.16	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.16	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000563.1	0.16	RiPP	venezuelin	Streptomyces venezuelae ATCC 10712
BGC0000926.1	0.16	Other	rhizocticin A	Bacillus subtilis subsp. spizizenii ATCC 6633

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000904.1	0.57	Other	FR-900098	Streptomyces rubellomurinus
BGC0000937.1	0.56	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0001739.1	0.53	Other	phosphonoacetic Acid	Streptomyces sp. NRRL F-525
BGC0002036.1	0.53	Other	dehydrofosmidomycin	Streptomyces lavendulae
BGC0001483.1	0.48	Other	5-isoprenylindole-3-carboxylate β-D-glycosyl ester	Streptomyces sp. RM-5-8
BGC0001538.1	0.47	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001591.1	0.47	Other	fatty acid enol ester	uncultured bacterium CSLC2
BGC0001688.1	0.47	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSLC2
BGC0000563.1	0.47	RiPP	venezuelin	Streptomyces venezuelae ATCC 10712
BGC0000926.1	0.47	Other	rhizocticin A	Bacillus subtilis subsp. spizizenii ATCC 6633

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c00005_NZ_CADI.. - Region 1 - arylpolyene

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Location: 34,469 - 78,071 nt. (total: 43,603 nt) Show pHMM detection rules used

arylpolyene: (APE_KS1 or APE_KS2)

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Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000836.1	0.30	Other	APE Ec	Escherichia coli CFT073
BGC0002008.1	0.26	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0001723.1	0.25	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000194.1	0.25	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)
BGC0000221.1	0.24	Polyketide	erdacin	uncultured soil bacterium V167
BGC0000228.1	0.22	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000220.1	0.22	Polyketide	enterocin	Streptomyces maritimus
BGC0001897.1	0.22	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0000253.1	0.22	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0001441.1	0.22	Other	belactosin A, belactosin C	Streptomyces sp.

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000836.1	0.64	Other	APE Ec	Escherichia coli CFT073
BGC0002008.1	0.59	Other	aryl polyenes	Xenorhabdus doucetiae
BGC0001723.1	0.58	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0000194.1	0.58	Polyketide	actinorhodin	Streptomyces coelicolor A3(2)
BGC0000221.1	0.57	Polyketide	erdacin	uncultured soil bacterium V167
BGC0000228.1	0.55	Polyketide	granaticin	Streptomyces violaceoruber
BGC0000220.1	0.55	Polyketide	enterocin	Streptomyces maritimus
BGC0001897.1	0.55	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10
BGC0000253.1	0.55	Polyketide	oviedomycin	Streptomyces antibioticus
BGC0001441.1	0.55	Other	belactosin A, belactosin C	Streptomyces sp.

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c00007_NZ_CADI.. - Region 1 - ectoine

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Location: 92,169 - 102,573 nt. (total: 10,405 nt) Show pHMM detection rules used

ectoine: ectoine_synt

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Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000853.1	0.51	Other	ectoine	Streptomyces anulatus
BGC0000855.1	0.42	Other	ectoine	Methylomicrobium kenyense
BGC0000859.1	0.41	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000856.1	0.41	Other	ectoine	Methylophaga thalassica
BGC0000852.1	0.39	Other	ectoine	Sporosarcina pasteurii
BGC0000857.1	0.35	Other	ectoine	Methylophaga alcalica
BGC0000860.1	0.35	Other	ectoine	Methylarcula marina
BGC0000858.1	0.33	Other	ectoine	Methylobacter marinus
BGC0000854.1	0.32	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0001917.1	0.14	Polyketide	5-alkyl-1,2,3,4-tetrahydroquinolines, streptoaminals	Streptomyces nigrescens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000853.1	0.79	Other	ectoine	Streptomyces anulatus
BGC0000855.1	0.73	Other	ectoine	Methylomicrobium kenyense
BGC0000859.1	0.73	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000856.1	0.73	Other	ectoine	Methylophaga thalassica
BGC0000852.1	0.71	Other	ectoine	Sporosarcina pasteurii
BGC0000857.1	0.68	Other	ectoine	Methylophaga alcalica
BGC0000860.1	0.68	Other	ectoine	Methylarcula marina
BGC0000858.1	0.66	Other	ectoine	Methylobacter marinus
BGC0000854.1	0.66	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0001917.1	0.43	Polyketide	5-alkyl-1,2,3,4-tetrahydroquinolines, streptoaminals	Streptomyces nigrescens

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c00009_NZ_CADI.. - Region 1 - NRPS

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Location: 56,568 - 88,886 nt. (total: 32,319 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000426.1	0.30	NRP	sevadicin	Paenibacillus larvae
BGC0000389.1	0.28	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000396.1	0.26	NRP	nodularin	Nostoc sp. 73.1
BGC0000465.1	0.26	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0001873.1	0.26	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0000342.1	0.26	NRP	enniatin	Fusarium equiseti
BGC0001149.1	0.26	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0000313.1	0.25	NRP	beauvericin	Beauveria bassiana
BGC0001399.1	0.25	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000351.1	0.25	NRP	exochelin	Mycolicibacterium smegmatis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000426.1	0.64	NRP	sevadicin	Paenibacillus larvae
BGC0000389.1	0.62	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000396.1	0.60	NRP	nodularin	Nostoc sp. 73.1
BGC0000465.1	0.60	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0001873.1	0.59	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0000342.1	0.59	NRP	enniatin	Fusarium equiseti
BGC0001149.1	0.59	NRP, Saccharide	brabantamide A	Pseudomonas sp. SHC52
BGC0000313.1	0.59	NRP	beauvericin	Beauveria bassiana
BGC0001399.1	0.59	NRP	fellutamide B	Aspergillus nidulans FGSC A4
BGC0000351.1	0.59	NRP	exochelin	Mycolicibacterium smegmatis

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 56567 - 88886:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X) + (D-asp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg9_62

Search NORINE for peptide: strict or relaxed

AMP-binding (16..408): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: val, leu, ile, abu, iva
Single AA prediction:: pip

Stachelhaus prediction details:

Stachelhaus sequence:: sympyGGPiK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 40% (weak)

ctg9_74

Search NORINE for peptide: strict or relaxed

CAL_domain (49..487): pk

minowa: NH2

Prediction, score:

NH2: 163.4
fatty_acid: 34.4
shikimic_acid: 15.3
AHBA: 12.5
Acetyl-CoA: 0.4

AMP-binding (1165..1562): X

NRPSPredictor2: glu, gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVWnMgLIhK
Nearest Stachelhaus code:: ser
Stachelhaus code match:: 70% (weak)

ctg9_76

Search NORINE for peptide: strict or relaxed

AMP-binding (5..270): asp

NRPSPredictor2: asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: asp, asn
Single AA prediction:: asp

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHVGK
Nearest Stachelhaus code:: asp
Stachelhaus code match:: 100% (strong)

AMP-binding (1382..1714): X

NRPSPredictor2: glu, gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: asp, asn, glu, gln, aad
Small clusters prediction:: glu, gln
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DgeDhGtVtK
Nearest Stachelhaus code:: gln
Stachelhaus code match:: 50% (weak)

c00011_NZ_CADI.. - Region 1 - NRPS

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Location: 1 - 3,024 nt. (total: 3,024 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

Legend:

core biosynthetic genes

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001758.1	0.27	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001833.1	0.25	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001135.1	0.25	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.1	0.25	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000427.1	0.25	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001641.1	0.24	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001844.1	0.24	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001479.1	0.23	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001128.1	0.23	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000307.1	0.23	NRP	AbT1	Aureobasidium pullulans

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001758.1	0.60	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001833.1	0.59	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0001135.1	0.58	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.1	0.58	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0000427.1	0.58	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001641.1	0.58	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001844.1	0.57	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001479.1	0.57	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001128.1	0.56	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000307.1	0.56	NRP	AbT1	Aureobasidium pullulans

Similar known gene clusters

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Detailed TIGRFAM domain annotation

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