LOCUS       c00002_NZ_CADI..       11857 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CADIKO010000002.1 Achromobacter aegrifaciens strain LMG 26854
            isolate LMG 26854, whole genome shotgun sequence.
ACCESSION   c00002_NZ_CADI..
VERSION     c00002_NZ_CADI..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:10:20
            Original ID  :: NZ_CADIKO010000002.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 514112
            Orig. end    :: 525969
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11857
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[519112:520969](-)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..6857)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="5000"
                     /product="siderophore"
                     /protocluster_number="1"
     cand_cluster    1..11857
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11857
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="siderophore"
                     /region_number="3"
                     /rules="IucA_IucC"
                     /tool="antismash"
     CDS             complement(611..1801)
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 100.9; E-value:
                     9.3e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_472"
                     /transl_table=11
                     /translation="MMVLMLGLLACVAPATIDAYLPAFAALEREFGVPQETVQLTLGVY
                     MFCYAAMLLLHGTLSDSLGRRRVILATLVCYIGGSALAAAAPSFGWLLAARALQGLSAG
                     AGIVVGQAIVRDCYEGPAAQRVMSYLILVFNLSPALAPIIGGQLAAQLGWRAVFVMLVA
                     LAATAWALCAWRLPETLPASRRRPLSGRALAGGYGALLADRRYVALAGAFSLIFAAQGL
                     LIGAAPDFIANVLGLPVTDFAYLFVPLVIGAMAGALFAARKAGRWTDQRITWLAYLLMG
                     GSCLASVMYAAGAGRPALPWAVILPAIYTCGLAMCVPAMTLHILARAPGLSGTAASVLG
                     FAQMLAFSVASGWGVPMVYGKPLGLALAMLACVAASAAGWAWLQRQSAPLANARSG"
     PFAM_domain     complement(752..1783)
                     /aSDomain="MFS_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07690.18"
                     /description="Major Facilitator Superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_472_0052"
                     /evalue="1.80E-41"
                     /label="ctg2_472"
                     /locus_tag="ctg2_472"
                     /protein_end="350"
                     /protein_start="6"
                     /score="142.3"
                     /tool="antismash"
                     /translation="GLLACVAPATIDAYLPAFAALEREFGVPQETVQLTLGVYMFCYAA
                     MLLLHGTLSDSLGRRRVILATLVCYIGGSALAAAAPSFGWLLAARALQGLSAGAGIVVG
                     QAIVRDCYEGPAAQRVMSYLILVFNLSPALAPIIGGQLAAQLGWRAVFVMLVALAATAW
                     ALCAWRLPETLPASRRRPLSGRALAGGYGALLADRRYVALAGAFSLIFAAQGLLIGAAP
                     DFIANVLGLPVTDFAYLFVPLVIGAMAGALFAARKAGRWTDQRITWLAYLLMGGSCLAS
                     VMYAAGAGRPALPWAVILPAIYTCGLAMCVPAMTLHILARAPGLSGTAASVLGFAQMLA
                     FSVA"
     CDS             complement(1979..2941)
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 82.9; E-value: 3.6e-25)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg2_473"
                     /transl_table=11
                     /translation="LNPSFPAVRFTVADFNRLGGHNGFRYQLPGFQAASADPDTVCIAE
                     GRVEEHAIRPGLTLVMSDVLVHHHYESTSVMTPRFSAIVMLQGQAQARVGNHDDLPLVA
                     QSGISAAYGDTVAMTGIHRAGQRLRSVNLSLSEPDAADDDPISDRIRKVLRTPAFRLRR
                     WQVQAHLMQSIEHLLECRWDDPLCAMLREGVGAQLLAHALAALDQQEPEPGTLSQRDRQ
                     LLERVRERLHSAPGEEHTLDDLAKLACMSPSTLRAKFRAAYQCSVFSWLRERRLEVARE
                     QLARGCSVQQAAHCVGYRHATNFATAFRERYGVAPSELN"
     PFAM_domain     complement(1985..2212)
                     /aSDomain="HTH_18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12833.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_473_0053"
                     /evalue="8.80E-20"
                     /label="ctg2_473"
                     /locus_tag="ctg2_473"
                     /protein_end="319"
                     /protein_start="243"
                     /score="70.8"
                     /tool="antismash"
                     /translation="LAKLACMSPSTLRAKFRAAYQCSVFSWLRERRLEVAREQLARGCS
                     VQQAAHCVGYRHATNFATAFRERYGVAPSEL"
     CDS             complement(3054..4220)
                     /locus_tag="ctg2_474"
                     /transl_table=11
                     /translation="MTDIGRLAHVEQALSPLHVRAYFDEDLYAREQEVIFKRSPLYVGH
                     EKAVPESGDWRRLPHEEGGRVLVRGAGGVELISNVCRHRQSLILGGETGAVAGPGKPAG
                     NLSATGGNIVCPLHRWTYDNRGQILGAPQFPSTPCLNLPRFPLKRCHGLLFEGPGDPLA
                     DLGDLFARPEFDFSDYVLDHVEVHQCNYNWKTFIEVYLEDYHVGPFHPGLGRFVTCEDL
                     SWEFGKRRSLQRVGVHDALEKPGSDVYRDWHGTLMRYRDGAPPDFGAIWVTYFPTHMIE
                     LYPHVLVLSTLYPKSPQETVNIAEFYYPEEIALFEREFVEAQRAAYMETAVEDDEIGER
                     MDAGRRALLRRGVSESGPYQSPMEDGMLHFHEWYRNIMGEHLGDCAAP"
     PFAM_domain     complement(3084..3692)
                     /aSDomain="Ring_hydroxyl_A"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00848.21"
                     /description="Ring hydroxylating alpha subunit (catalytic
                     domain)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_474_0055"
                     /evalue="3.60E-34"
                     /label="ctg2_474"
                     /locus_tag="ctg2_474"
                     /protein_end="379"
                     /protein_start="176"
                     /score="118.7"
                     /tool="antismash"
                     /translation="SDYVLDHVEVHQCNYNWKTFIEVYLEDYHVGPFHPGLGRFVTCED
                     LSWEFGKRRSLQRVGVHDALEKPGSDVYRDWHGTLMRYRDGAPPDFGAIWVTYFPTHMI
                     ELYPHVLVLSTLYPKSPQETVNIAEFYYPEEIALFEREFVEAQRAAYMETAVEDDEIGE
                     RMDAGRRALLRRGVSESGPYQSPMEDGMLHFHEWYRNIMG"
     PFAM_domain     complement(3813..4100)
                     /aSDomain="Rieske"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00355.28"
                     /description="Rieske [2Fe-2S] domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_474_0054"
                     /evalue="4.00E-09"
                     /label="ctg2_474"
                     /locus_tag="ctg2_474"
                     /protein_end="136"
                     /protein_start="40"
                     /score="36.4"
                     /tool="antismash"
                     /translation="LYVGHEKAVPESGDWRRLPHEEGGRVLVRGAGGVELISNVCRHRQ
                     SLILGGETGAVAGPGKPAGNLSATGGNIVCPLHRWTYDNRGQILGAPQFPS"
     CDS             complement(4258..5004)
                     /locus_tag="ctg2_475"
                     /transl_table=11
                     /translation="VTRELDDLLALAGRLAPGLDGRVGPPAAPGIRPGASNADAIARLR
                     DWWRERHPEAGQHYLALRCWGLLIWQPVYLCVIAAHRSAIVPDLTRLSQPVANGFIAGY
                     TMERHEPLRGGLEARLDAAATQLREIGALFQRELGAALRLNSRATACMQADCVLSALLA
                     ARTGVSAADNAWATAAAADWLARLGIAGSSGYLNYQRRSLPAITVDRQVCCHHFRRSDG
                     DYCSTCPKLDIAERIARIDAESVEPA"
     PFAM_domain     complement(4315..4377)
                     /aSDomain="FhuF_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF11575.10"
                     /description="FhuF 2Fe-2S C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_475_0056"
                     /evalue="1.70E-04"
                     /label="ctg2_475"
                     /locus_tag="ctg2_475"
                     /protein_end="230"
                     /protein_start="209"
                     /score="21.5"
                     /tool="antismash"
                     /translation="RQVCCHHFRRSDGDYCSTCPK"
     aSDomain        complement(4315..4983)
                     /aSDomain="TIGR03950"
                     /aSTool="tigrfam"
                     /description="sidero_Fe_reduc: siderophore ferric iron
                     reductase, AHA_1954 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_475_0008"
                     /evalue="8.10E-62"
                     /identifier="TIGR03950"
                     /label="ctg2_475"
                     /locus_tag="ctg2_475"
                     /protein_end="230"
                     /protein_start="7"
                     /score="206.9"
                     /tool="antismash"
                     /translation="LLALAGRLAPGLDGRVGPPAAPGIRPGASNADAIARLRDWWRERH
                     PEAGQHYLALRCWGLLIWQPVYLCVIAAHRSAIVPDLTRLSQPVANGFIAGYTMERHEP
                     LRGGLEARLDAAATQLREIGALFQRELGAALRLNSRATACMQADCVLSALLAARTGVSA
                     ADNAWATAAAADWLARLGIAGSSGYLNYQRRSLPAITVDRQVCCHHFRRSDGDYCSTCP
                     K"
     CDS             complement(5001..6857)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_476"
                     /sec_met_domain="IucA_IucC (E-value: 1.9e-75, bitscore:
                     250.1, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPHATTHPAQVASHLEPEVWAKVNRLLVRKAISEYTHEGLLQPE
                     RLGPADTPGFDRYRLALADGRVEYRYDAQLMAMRHWRIRAESIARTTAGAPAPLDALQF
                     VIEIRDKLRIPEDRLPIYLDEIASTLHGAAYKHTRACLPAPELALADYQTIETSMIEGH
                     PSFVANNGRLGFDAEDYHAYAPEAAAPIRVMWLAVHKDNAHFACLSTMDYASLLRGELG
                     EDAVARHAATLQGQGLAPADYYLMPAHPWQWFNKLSLAFAPYVAERKIVCLGYGEDDYL
                     AQQSIRTFFNISQPGKHYVKTSLSILNMGFMRGLSPYYMSGTPAINEYIHGLIASDPWL
                     RANGFTILREAASLGFRNYYYEAAISVDTPYKKMFSALWRENPQALIGPGERLMTMAAL
                     LHVDPQGLALLPALIRASGLSAAAWLERYVDAYLTPLVHCFYTHDLVFMPHGENVILVI
                     RDHVPVRAFMKDIAEESSILDPQADLPENARRLAADVPEEYKLLTIFVDVFEGYFRHLS
                     QILADTGLMQEDDFWELVAGRIAAYQQAHPQRLEKYRRYDLYAPDMIHSCLNRLQLANN
                     LQMVNLADPIGSFQMAPRLPNPVAPYRPQWLDRTADAAQALA"
     PFAM_domain     complement(5124..5591)
                     /aSDomain="FhuF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06276.14"
                     /description="Ferric iron reductase FhuF-like transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_476_0058"
                     /evalue="1.20E-38"
                     /label="ctg2_476"
                     /locus_tag="ctg2_476"
                     /protein_end="578"
                     /protein_start="422"
                     /score="133.2"
                     /tool="antismash"
                     /translation="AWLERYVDAYLTPLVHCFYTHDLVFMPHGENVILVIRDHVPVRAF
                     MKDIAEESSILDPQADLPENARRLAADVPEEYKLLTIFVDVFEGYFRHLSQILADTGLM
                     QEDDFWELVAGRIAAYQQAHPQRLEKYRRYDLYAPDMIHSCLNRLQLANNLQ"
     PFAM_domain     complement(5655..6407)
                     /aSDomain="IucA_IucC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04183.14"
                     /description="IucA / IucC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_476_0057"
                     /evalue="2.30E-74"
                     /label="ctg2_476"
                     /locus_tag="ctg2_476"
                     /protein_end="401"
                     /protein_start="150"
                     /score="250.1"
                     /tool="antismash"
                     /translation="DYQTIETSMIEGHPSFVANNGRLGFDAEDYHAYAPEAAAPIRVMW
                     LAVHKDNAHFACLSTMDYASLLRGELGEDAVARHAATLQGQGLAPADYYLMPAHPWQWF
                     NKLSLAFAPYVAERKIVCLGYGEDDYLAQQSIRTFFNISQPGKHYVKTSLSILNMGFMR
                     GLSPYYMSGTPAINEYIHGLIASDPWLRANGFTILREAASLGFRNYYYEAAISVDTPYK
                     KMFSALWRENPQALIGPGERLMTMAALLH"
     CDS             complement(6854..7459)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203:putative siderophore biosynthesis protein (Score:
                     134.2; E-value: 1.3e-40)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_477"
                     /transl_table=11
                     /translation="MLTMTATFLGEVVRQSRDHYDEGRGLALRPLVPDADAALLRQWFS
                     MDYARFWSMQRHSEDQVRDFYDALCGSGHASAWLGSHEGQPAFLVECYDPARDEVGEHY
                     AVRPGDLGMHLFIGPPRLRIPGFSRQVFAFVMRFMFDRLDAARIVVEPDANNAKIHALN
                     LAMGFTYAGQARFRDKTASLAFCTRTQFEQVQYQESTP"
     PFAM_domain     complement(6935..7363)
                     /aSDomain="Acetyltransf_8"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13523.8"
                     /description="Acetyltransferase (GNAT) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_477_0059"
                     /evalue="9.70E-46"
                     /label="ctg2_477"
                     /locus_tag="ctg2_477"
                     /protein_end="175"
                     /protein_start="32"
                     /score="155.1"
                     /tool="antismash"
                     /translation="PDADAALLRQWFSMDYARFWSMQRHSEDQVRDFYDALCGSGHASA
                     WLGSHEGQPAFLVECYDPARDEVGEHYAVRPGDLGMHLFIGPPRLRIPGFSRQVFAFVM
                     RFMFDRLDAARIVVEPDANNAKIHALNLAMGFTYAGQAR"
     CDS             complement(7477..8844)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1080:lysine/ornithine N-monooxygenase (Score: 389.9;
                     E-value: 2.2e-118)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_478"
                     /transl_table=11
                     /translation="MNREIHDFAAIGLGPFNLSLACLAAPLSGVRAVFLDKKPGFDWHP
                     GMLIEDSTLQNPFLADLVSLADPRSEYSYLNYCKQTGRIYSYYMRENHYLNRAEYNRYC
                     KWVAARLPNLRFNHDVQSVLHDPDSRAYLVTGQHAVSGERFMVRCRKLVLGLGTHPQLP
                     ECCDPRTAPYIHSADYLRHKPQLQRRQGITIVGSGQSAAEVFHDLLRDSAKHAYSLTWI
                     TRSPRFFQMENTKLTLELISPDYTDYFHDLPEARRREMLRQQSSLYKGINASLINQIYD
                     LLDEKIRAGDRRYTLLTSAELRASRHERATGRYHLDFMHVDTGQPFKHVTDGLVLATGY
                     APRIPACVNPISDRIAWDENGGYRIAHNYAVDRAGTEIFVQNTGLLSHGVTNPDLGFCC
                     YRNSQILRDLTGVEHYAIEPRTALQDFRPPANGVLAHRLGMPEPMPMMDGHRAATI"
     PFAM_domain     complement(7822..8835)
                     /aSDomain="K_oxygenase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13434.8"
                     /description="L-lysine 6-monooxygenase (NADPH-requiring)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_478_0060"
                     /evalue="1.60E-118"
                     /label="ctg2_478"
                     /locus_tag="ctg2_478"
                     /protein_end="341"
                     /protein_start="3"
                     /score="395.9"
                     /tool="antismash"
                     /translation="EIHDFAAIGLGPFNLSLACLAAPLSGVRAVFLDKKPGFDWHPGML
                     IEDSTLQNPFLADLVSLADPRSEYSYLNYCKQTGRIYSYYMRENHYLNRAEYNRYCKWV
                     AARLPNLRFNHDVQSVLHDPDSRAYLVTGQHAVSGERFMVRCRKLVLGLGTHPQLPECC
                     DPRTAPYIHSADYLRHKPQLQRRQGITIVGSGQSAAEVFHDLLRDSAKHAYSLTWITRS
                     PRFFQMENTKLTLELISPDYTDYFHDLPEARRREMLRQQSSLYKGINASLINQIYDLLD
                     EKIRAGDRRYTLLTSAELRASRHERATGRYHLDFMHVDTGQPFKHVTDGLVLATGYA"
     CDS             9239..9466
                     /locus_tag="ctg2_479"
                     /transl_table=11
                     /translation="VRPEDCLKYPLLQDSDRVDWPLWLQAHGVDARKEAQRGPSYEDDL
                     LLLLLLLLLLLLLLLLLLLLLLPPRGRASR"
     CDS             9561..10187
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 135.4; E-value:
                     4.3e-41)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_480"
                     /transl_table=11
                     /translation="MPTITSEPGPLFTLRGIYSERLSPVSLDLAAGECAAIMGPSGSGK
                     SLLLRQAADLDPGHGEALLDGRPRSGMRGYEWRRQVMYCQAEAGWWDDLVARHFTDRAR
                     ALAIMQRLGLSADKLDALVHELSTGERQRLGLVRALALAPRVLLLDEPTAALDQAATDQ
                     VEAELRRYLEGGAGILMVTHSPAQAERLARRSWRMEQGRLEPLWT"
     PFAM_domain     9624..10022
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_480_0061"
                     /evalue="4.60E-24"
                     /label="ctg2_480"
                     /locus_tag="ctg2_480"
                     /protein_end="154"
                     /protein_start="21"
                     /score="85.6"
                     /tool="antismash"
                     /translation="LSPVSLDLAAGECAAIMGPSGSGKSLLLRQAADLDPGHGEALLDG
                     RPRSGMRGYEWRRQVMYCQAEAGWWDDLVARHFTDRARALAIMQRLGLSADKLDALVHE
                     LSTGERQRLGLVRALALAPRVLLLDEPTA"
     CDS             10178..10975
                     /locus_tag="ctg2_481"
                     /transl_table=11
                     /translation="MDVIKLQASDLAIASLLVLLSAGISFALRLNLQRQVLWAALRTVV
                     QLLLVGHILRIVFAHAAPWLTALVVAVMMALAAREVAARPKARLTQRGNGWVGAMAVAG
                     TTVITVLFILNTALRPDPWYDPRYTIALIGIVLGSVLNAASLALDGVLSGARREKLAIE
                     ARLALGATVHEAFSSLLRESVRRGIVPSINQMSAAGIITLPGIMTGQIIAGMDPIEAAK
                     YQILLMFLLCGASGMAAIAAAYGAMRRLTDERGRLRLDRLHPS"
     aSDomain        10199..10936
                     /aSDomain="TIGR00245"
                     /aSTool="tigrfam"
                     /description="TIGR00245: TIGR00245 family protein"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_481_0009"
                     /evalue="2.60E-53"
                     /identifier="TIGR00245"
                     /label="ctg2_481"
                     /locus_tag="ctg2_481"
                     /protein_end="253"
                     /protein_start="7"
                     /score="178.9"
                     /tool="antismash"
                     /translation="ASDLAIASLLVLLSAGISFALRLNLQRQVLWAALRTVVQLLLVGH
                     ILRIVFAHAAPWLTALVVAVMMALAAREVAARPKARLTQRGNGWVGAMAVAGTTVITVL
                     FILNTALRPDPWYDPRYTIALIGIVLGSVLNAASLALDGVLSGARREKLAIEARLALGA
                     TVHEAFSSLLRESVRRGIVPSINQMSAAGIITLPGIMTGQIIAGMDPIEAAKYQILLMF
                     LLCGASGMAAIAAAYGAMRRLTDE"
     PFAM_domain     10205..10927
                     /aSDomain="UPF0014"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03649.15"
                     /description="Uncharacterised protein family (UPF0014)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_481_0062"
                     /evalue="1.90E-75"
                     /label="ctg2_481"
                     /locus_tag="ctg2_481"
                     /protein_end="250"
                     /protein_start="9"
                     /score="253.4"
                     /tool="antismash"
                     /translation="DLAIASLLVLLSAGISFALRLNLQRQVLWAALRTVVQLLLVGHIL
                     RIVFAHAAPWLTALVVAVMMALAAREVAARPKARLTQRGNGWVGAMAVAGTTVITVLFI
                     LNTALRPDPWYDPRYTIALIGIVLGSVLNAASLALDGVLSGARREKLAIEARLALGATV
                     HEAFSSLLRESVRRGIVPSINQMSAAGIITLPGIMTGQIIAGMDPIEAAKYQILLMFLL
                     CGASGMAAIAAAYGAMRRL"
ORIGIN
        1 cggtcgtaga tggcggcgtc catgtcggtg gagccatagt tccattggct caggatcggg
       61 gcgttcaggc cgtcgaactg gaagttgtct atcgcgaagc cgcgtgccga gaacgacagg
      121 cggttgctgt cgctgcgcgt gaccgagatg ccgggcgcgc tggccaggat ggaaccggtg
      181 tcctgcagtc cctggtcctc gatctgctgg cgggtcacca cgctgaccga ttgcggggtc
      241 tcccgcggcg acagcgtcag gccggtcgcg gtgctcatgg cctcggtgtt gtaggcatgg
      301 gtgccttcgg tggtgccggg tatgccggcg ccccgaaccg tgacggccgg gagttcggcg
      361 ggctggtcgg cgccggatga gacgctggat tgcgcgttgg cggcgtggta gggcaaggct
      421 gagcacagca aggccgcgcg gacggccagg gcaagcagat tcgcccggcg cggaagcgcg
      481 cgcggcgggg acagtgcggg ggacatgaac acaagctccg gctgaaaaat ttggtaatga
      541 gaattattgt ttttgctgga gacttgaacg tatgccggaa gatgcgatgc gtatgccgaa
      601 cgccgccgca tcaacccgag cgggcgttcg ccaaaggcgc ggactgccgt tgcagccagg
      661 cccagcctgc cgcgcttgcg gcgacgcagg ccagcatcgc aagcgccagg ccgaggggct
      721 tgccatagac catgggcacg ccccagccgc tggcgaccga aaaggccagc atctgggcga
      781 agccgagcac cgaagcggcg gtgccggaca gccctggcgc acgggccagg atgtgcaggg
      841 tcatggccgg gacgcacatg gccaggccgc aggtatagat ggcgggcagg atgaccgccc
      901 agggcagggc gggtcgcccg gcgccagcgg catacatgac gcttgccagg caactgccgc
      961 ccatcagcag gtacgccagc caggtgatgc gttgatccgt ccagcgtccg gccttgcgcg
     1021 ccgcgaacag cgcgcccgcc atggcgccga tcacgagcgg cacgaacaga tatgcgaaat
     1081 ccgttacggg caggcccagg acgttggcaa tgaagtctgg tgcggcgccg atgagcaagc
     1141 cctgggccgc gaagatcagg ctgaaggcgc cggcgagcgc gacgtatcgc cggtccgcaa
     1201 gcagcgcgcc gtagccgcca gccagtgcac gcccggacag cggccggcgc cggctggcgg
     1261 gcagggtttc gggcagccgc caggcgcata gcgcccaggc cgtcgcggcc agggcgacaa
     1321 gcatcacaaa gacggcgcgc cagcccaact gcgccgccaa ctggccgccg atgatgggcg
     1381 ccaacgccgg cgacagattg aacaccagga tgagatagga catgacgcgt tgcgccgccg
     1441 gcccttcgta gcagtcgcgc acgatggcct ggcccaccac gatgccggcg cctgcggaca
     1501 ggccttgcaa cgcccgcgcg gccaacagcc agccgaagct cggcgcggcg gcggccagcg
     1561 cgctgccgcc gatgtagcaa accagcgtcg ccaggatgac gcggcgccgg cccagcgaat
     1621 ccgacagcgt tccatgcagc agcagcatcg ccgcgtagca gaacatgtag acgcccaggg
     1681 tcagctgcac ggtttcttgc ggcacgccga actcccgctc cagcgcggcg aaggcgggca
     1741 gataggcgtc gatggtggcg ggcgccacgc aggccagcag gcccagcatc agcaccatca
     1801 tgggaaagga agtcggtttg tcggggctgg gcacgggagc gtccggggca ggagcttccc
     1861 ggggcgggaa gcgtggcctc atggtcgccc gccagccgcg gtcggatgaa tgggcaatgc
     1921 cgcaagaaca atggatgctg ccgaaagccg cgggccgggg cgctcacggc agccccgttc
     1981 agttcagttc gctgggcgcg acgccatagc gctcgcggaa cgccgtggcg aaattggtgg
     2041 catgccgata gcccacgcag tgcgcggcct gctgcacgct gcagccgcga gccaattgct
     2101 cgcgggcgac ctccagccgg cgctcgcgca gccagctgaa cacggagcat tgataggcgg
     2161 cgcggaactt ggcgcgcagg gtgctggggc tcatgcaggc cagtttcgcc agatcatcca
     2221 gggtgtgctc ttcgccaggc gcgctgtgca gccgttcccg cacgcgctca agcaactggc
     2281 ggtcgcgctg cgacagcgtg ccgggttcgg gctcctgctg gtccagcgca gccaacgcat
     2341 gggccagaag ctgcgcgccg acgccttcgc gcagcatggc gcacagcggg tcgtcccaac
     2401 ggcattccag cagatgttcg atggactgca tcagatgcgc ctgcacctgc cagcggcgca
     2461 gccggaaggc gggcgtgcgc aggactttgc ggatccgatc gctgatcggg tcgtcgtccg
     2521 cggcgtccgg ctcggacagc gacaggttga cgctgcgcag ccgttggccg gcacggtgga
     2581 tgccggtcat agcgaccgta tcgccgtagg cggcgctgat accgctttgg gcgaccagcg
     2641 gcaggtcgtc gtggttgccg acgcgcgcct gagcctggcc ctggagcatg acgatggccg
     2701 aaaagcgcgg cgtcatgacc gaggtcgatt cgtagtggtg atgaaccagc acgtcggaca
     2761 tgaccagcgt caggccgggg cggatggcat gttcctcgac gcggccttcg gcgatgcaga
     2821 cggtgtccgg gtcggcgcta gcggcctgga atccgggcaa ctggtagcgg aaaccgttat
     2881 ggccgcccag gcggttgaag tcggcgacgg tgaatcggac tgcggggaag gagggattca
     2941 atggcgtcac tcgcacggcg ggttgagccc cccggacgtc ggccagggga agtggcgggg
     3001 tctaaatgag aatagcatat attcgcattt attcaacggt ctggcagcgg cgctcagggc
     3061 gcggcgcaat cgcccaaatg ctcgcccatg atgttgcgat accactcgtg gaagtgcagc
     3121 atgccgtcct ccatgggaga ctggtacggg ccgctctcgc tgacgccgcg ccgcagcagc
     3181 gcgcgtctgc cggcatccat gcgctcgccg atttcgtcgt cctcgaccgc cgtttccatg
     3241 taggccgcgc gttgcgcttc gacgaattcg cgttcgaaca gggcgatttc ctcgggatag
     3301 tagaactcgg cgatgttgac cgtctcctgc gggcttttgg ggtagagcgt ggacagcacc
     3361 agcacgtgcg ggtagagctc gatcatgtgg gtgggaaagt aggtcaccca gatcgcgccg
     3421 aaatccggag gcgcgccgtc gcggtagcgc atcagggtgc cgtgccagtc gcggtatacg
     3481 tcggaaccgg gcttctccag ggcgtcgtgc actcccacgc gctgcaggct gcggcgcttg
     3541 ccgaactccc agctcagatc ctcgcaggtg acgaagcgcc ccagcccggg gtggaacggc
     3601 ccgacgtggt agtcctccag atagacctcg atgaaggtct tccagttgta gttgcattgg
     3661 tgcacttcga cgtggtccag cacatagtcc gagaagtcga actcgggccg ggcgaacagg
     3721 tcgcccaggt ccgctagcgg gtcgcccggc ccctcgaata gcaggccgtg gcagcgcttc
     3781 aggggaaacc gcggcaggtt caggcagggc gtgctgggga attgcggcgc gcccaggatc
     3841 tggccgcgat tgtcataggt ccagcgatgc agcgggcaga cgatgttgcc gcccgtggcc
     3901 gacagattgc ccgccggctt gcccggcccg gcgacggcgc cggtctcgcc gcccaggatc
     3961 agcgactggc ggtggcggca tacgttggat atcagttcca cgccgccggc gccgcgcacg
     4021 aggacgcgcc cgccttcctc gtgcggcagc ctgcgccagt cgccggattc gggcacggct
     4081 ttttcgtgcc cgacatacag cggcgagcgc ttgaatatca cctcctgttc ccgggcgtac
     4141 aggtcttcgt cgaaatatgc ccgcacgtgc agcgggctga gcgcctgctc gacgtgtgca
     4201 aggcggccta tgtccgtcat gtccgactcc ttgtgccttg cgcaaggcgg ccgcccgtca
     4261 ggcgggctcg acgctctcgg cgtcgatccg ggcgatgcgt tcggcaatat ccagtttggg
     4321 gcaggtgctg cagtagtcgc cgtcgcttct gcggaagtgg tgacagcaga cctgccggtc
     4381 cacggtgatg gccggtagcg accgccgctg atagttcagg tagccgctgc tgcccgcgat
     4441 gcccaggcgc gcaagccaat cggccgcggc tgcggtggcc caggcattgt cggcggcgct
     4501 cacgcccgtt cgagccgcca acagggcgga caggacgcag tcggcctgca tgcaggcggt
     4561 ggcccgcgaa ttgaggcgca gcgccgcgcc cagctcgcgc tggaacaggg cgccgatctc
     4621 gcgcagctgc gtggcggccg cgtccagccg cgcctccagg ccgccgcgca ggggttcatg
     4681 gcgttccatg gtgtagccgg cgatgaagcc gttggcgacc ggctggctga gccgggtcag
     4741 gtccgggacg atggcgctgc gatgcgcggc gattacgcag aggtacacgg gctgccagat
     4801 caacaggccc cagcagcgca gcgccaggta gtgctggccg gcttctggat ggcgttcgcg
     4861 ccaccagtcg cgcaaccgcg cgatggcgtc ggcgttgctc gcgcccggac ggatgccggg
     4921 cgcggctggc gggcccacgc gcccgtcaag gccaggcgcg aggcggcccg ccagcgcgag
     4981 cagatcgtcc agttcgcggg tcacgcaagg gcctgcgcgg cgtcggcagt ccggtccagc
     5041 cattgcggcc ggtaaggcgc cacggggttg ggcagcctgg gcgccatctg gaagctgccg
     5101 atgggatcgg ccagattgac catctgcagg ttgttggcga gctgcaggcg gttcaggcac
     5161 gagtggatca tgtccggcgc gtacaggtcg tagcggcggt atttttcgag ccgctgcgga
     5221 tgtgcctgct ggtaggcggc gatacggccc gcgaccagct cccagaaatc gtcctcctgc
     5281 atgaggccgg tgtcggccag gatctgggac agatggcgga agtagccctc gaacacgtcg
     5341 acgaagatcg tcaggagctt gtattcctcg ggcacgtccg ccgccagccg ccgcgcgttc
     5401 tcgggcaggt cggcctgcgg gtcgaggatg gaggattcct cggcgatgtc cttcatgaag
     5461 gcgcgcaccg gcacatggtc ccggatcacc aggatcacgt tctcgccatg cggcatgaac
     5521 accaggtcat gggtgtagaa gcaatgcacc agcggcgtca ggtaggcatc cacatagcgt
     5581 tccagccacg cggcggcgct caaccccgag gcccggatca gcgcgggcag cagggctagg
     5641 ccctgcggat ccacgtgcag aagcgcggcc atggtcatca gccgttcgcc gggaccgatc
     5701 agcgcctgcg gattctcgcg ccatagcgcc gagaacatct tcttgtaggg cgtgtcgacg
     5761 gaaatcgcag cttcatagta gtagttgcgg aatcccaggc tggcggcctc gcgcaggatg
     5821 gtgaagccat tggcgcgcag ccaggggtcg gacgcgatca ggccgtggat gtattcgttg
     5881 atggcgggcg tgcccgacat gtaatagggc gacaacccgc gcatgaaacc catgttcagg
     5941 atcgacagcg aggtcttcac ataatgcttg cccggctggc tgatgttgaa gaaggtgcgt
     6001 atcgactgct gtgccaggta gtcgtcttcg ccgtaaccca ggcatacgat cttgcgttcg
     6061 gccacatagg gtgcgaacgc cagcgacagc ttgttgaacc actgccaggg gtgcgccggc
     6121 atcaagtagt agtcggcggg ggccagtccc tggccttgca gcgtggcggc gtggcgcgcc
     6181 acggcgtcct cgccgagttc gccgcgcaac aggctggcgt agtccatggt ggacaggcag
     6241 gcgaaatgcg cgttgtcctt gtgcaccgcc agccacatca cgcggatcgg ggcagcggcc
     6301 tccggcgcat aggcgtggta gtcctcggcg tcgaaaccca ggcggccgtt gttggcgacg
     6361 aagctggggt gtccttcgat catcgaggtt tcgatggtct gatagtcggc cagcgcgagt
     6421 tcgggggcgg gcaggcaagc gcgcgtgtgc ttgtaggcgg cgccgtgcag cgtgctggcg
     6481 atttcgtcca gatagatcgg cagccggtct tccggaatgc gcagcttgtc gcggatctcg
     6541 atcacgaact gcagggcgtc caggggcgcg ggcgcgccgg ccgtggtcct ggcgatcgat
     6601 tccgcgcgga tgcgccagtg gcgcatggcc atcagttgcg cgtcgtagcg gtactcgacg
     6661 cggccgtccg cgagcgccag gcgatagcgg tcgaaccccg gcgtgtccgc cgggcccagg
     6721 cgttcgggtt gcagcaggcc ttcatgggtg tactcggaga tggccttgcg cacgagcagg
     6781 cggttgacct tggcccagac ttccggctcc agatggctgg cgacctgcgc gggatgagtg
     6841 gtggcatgcg gattcatggg gtcgactcct ggtattggac ctgttcgaac tgtgtacgtg
     6901 tgcagaacgc cagactggcg gtcttgtcgc ggaatcgggc ctggcctgca taggtgaatc
     6961 ccatggccag attgagcgcg tggatcttgg cgttgttcgc gtcgggctcg accacgatgc
     7021 gcgcggcatc cagccggtcg aacatgaagc gcatcacgaa ggcgaacacc tgccggctga
     7081 agccgggaat ccgcaagcgc ggcgggccga tgaaaagatg catgccgagg tcgcctggcc
     7141 gcaccgcgta gtgttcgccg acttcgtcgc gggcggggtc gtagcactcc accagaaagg
     7201 ctggctgtcc ctcatggctg ccgagccagg cgctggcgtg tccgctgccg catagggcgt
     7261 catagaagtc gcgcacctgg tcctcgctgt gccgctgcat ggaccagaag cgcgcgtagt
     7321 ccatggaaaa ccattgccgc agcagcgcgg cgtccgcatc cggaaccagg gggcgcaagg
     7381 cgagtccccg gccctcgtcg taatggtcgc gcgactggcg cacgacctcg cccagaaagg
     7441 tggctgtcat cgtgagcatg ctggctcccc gcaagatcag atggtggcgg cccgatggcc
     7501 gtccatcatg ggcatcggct ccggcatgcc gaggcggtgc gccagtacgc cgttcgccgg
     7561 cgggcggaag tcctgcagtg cggtgcgagg ctcgatggcg tagtgctcca cgccggtcag
     7621 gtcgcgcagt atctgcgaat tgcggtagca gcagaatccc aggtcgggat tcgtgacgcc
     7681 atggctgagc agcccggtgt tctgcacgaa gatctccgtg ccggcgcggt ccacggcgta
     7741 gttgtgggcg atgcggtagc cgccgttttc atcccaggcg atccggtcgc tgatggggtt
     7801 gacgcaggcg gggatgcgcg gggcgtagcc ggtggccagc accaggccgt ccgtcacgtg
     7861 cttgaacggt tggccggtgt caacgtgcat gaagtccaga tggtagcggc ccgtggcgcg
     7921 ctcatgccgg ctggcgcgca gttccgcgct ggtgagcagc gtgtagcggc ggtcgcctgc
     7981 gcggatcttc tcgtccagga ggtcgtatat ctgattgatc agcgaggcgt tgatgccctt
     8041 gtacaggctg ctttgctggc gcagcatctc gcgccgccgg gcttcgggca ggtcgtggaa
     8101 atagtcggtg tagtcgggag agatcagctc cagcgtgagc ttggtgttct ccatctggaa
     8161 gaagcggggc gagcgggtga tccaggtcag gctgtaggcg tgcttggcgc tgtcgcgcag
     8221 caggtcgtgg aacacttcgg ccgcgctctg tccgctgccg acgatggtga tgccctgcct
     8281 gcgctgcagc tggggcttgt ggcgcaagta gtccgcgctg tggatgtagg gcgcggtgcg
     8341 cggatcgcag cattcaggca gctgggggtg cgtgcccagt cccaacacca gcttgcggca
     8401 gcggaccatg aagcgttcgc cactgacggc atgctggccg gtcaccaggt aggcgcggct
     8461 gtctggatcg tgcagcacgc tctgcacgtc gtgattgaag cgcaggttcg gcaggcgggc
     8521 cgcgacccat ttgcagtagc ggttgtactc ggcccggttc aggtagtggt tttcgcgcat
     8581 gtaataggaa tagatgcgcc cggtctgttt gcagtaattc agatagctgt attcgctacg
     8641 cgggtccgcc aggctcacga ggtccgccag aaaggggttc tgcaaggtgg agtcctcgat
     8701 cagcattccg gggtgccaat cgaagcctgg cttcttgtcc aggaaaaccg cgcgcacgcc
     8761 ggacaagggc gcggccaggc aggcgagact gaggttgaac gggccaagac cgatggcggc
     8821 gaagtcatgg atttcacggt tcatatggga tctgcctttt gccggagccg gcattgcgtg
     8881 aacatgattc tcttctgggg atgattatca ttttcaatat gatcactcta gcaaatgccg
     8941 atttattgcg gtgtcttgcc tgtgtgttgc aggcggcacc catatgcagc gtggcgtatc
     9001 gcatagggag cctcatcgga tttggatttt tcagataagc gcagctattt gcatccggac
     9061 agcgaggttc gcgtggctgc atcgtcaaaa ttggtcaatt tcaagcgcga ccgcatcgac
     9121 gtggcgttgc ggcatggcct ggggctttac ccgggctgtc ggccttccgg ctgatgccgc
     9181 cggtgctgct gctactgccc gtggccagcc ccgccatgct ggcgcaaggc cccccatcgt
     9241 gcggcccgaa gactgcctga agtacccgct gctgcaggat tccgaccgcg tggactggcc
     9301 cttgtggctg caggcgcacg gcgtggacgc caggaaggaa gcgcagcgcg gcccgagcta
     9361 cgaggacgat ctgctgctgc tgctgctgct gctgctgctg ctgctgctgc tgctgctgct
     9421 gctgctgctg ctgctgctgc cgccgcgggg cagggcatcg cgctgatgca agacacacat
     9481 gcgcgcgagg acatcgaatc gggccggctg gccattgcct tggaccagcc tcgcgcattt
     9541 acggtctaag atcgataccc atgccgacca ttacgtctga accagggccg ctgttcacgc
     9601 tgcgcggcat ctacagcgaa cgcctctctc ccgtcagcct ggatctcgcc gcgggcgagt
     9661 gcgcagccat catgggtcct tcgggctcag gcaaatccct gttgctgcgc caggccgccg
     9721 acctggaccc cgggcatggc gaggccttgc tggatggccg gccgcgctcg ggcatgcggg
     9781 gctacgaatg gcgccggcag gtcatgtact gccaggccga ggccggctgg tgggacgacc
     9841 tggtcgcgcg gcatttcacg gaccgcgccc gggccttggc catcatgcaa cgcctggggc
     9901 tgtccgcgga caagctggac gccttggtgc atgaactgtc cacgggcgaa cgccagcgcc
     9961 tgggcctggt gcgcgcattg gcgctggcgc cgcgcgtgct gctgctggac gagccgaccg
    10021 cggcgctgga ccaggcggcc acggatcagg tcgaagcgga gctgcggcgc tacctggagg
    10081 gcggggcggg gatcctgatg gtgacccata gtccagccca ggccgaacgg cttgcgcggc
    10141 gttcctggcg catggaacaa ggcaggttgg agccgctatg gacgtgatca agctgcaggc
    10201 ctcggacctg gccattgcct cgctgctggt gctgctcagc gccggcattt ccttcgcctt
    10261 gcgcttgaac ctgcagcgac aggtactgtg ggccgcgctg cgcaccgtgg tgcagctgct
    10321 gctggtcggc cacattctgc gcatcgtgtt cgcgcacgcc gccccgtggc tgacggcgct
    10381 ggtggtggcg gtgatgatgg cgctggcggc cagggaggtc gccgcgcgcc cgaaggccag
    10441 gctgacgcaa cgcggaaacg gctgggtcgg cgcgatggcg gtggcgggga ccacggtcat
    10501 cacggtgctg ttcatcctga acacggcgct gcgtccggac ccctggtacg acccgcgcta
    10561 caccatcgcg ctgatcggca tcgtgttggg cagcgtgctc aacgccgcca gcctggcgct
    10621 ggacggggtg ctgtccggcg ctcgccggga aaagctggcg atcgaggcga ggctggcgct
    10681 gggcgcgacc gtgcacgagg cattttcgtc cttgctgcgc gaatccgtgc ggcgcggcat
    10741 cgtgcccagc atcaaccaga tgtcggccgc cggcatcatc acgctgccgg gcatcatgac
    10801 cgggcagatc atcgccggca tggatccgat cgaggccgcc aagtaccaga tcctgctgat
    10861 gttcctgctg tgcggcgcca gcggcatggc ggcgatcgcc gcagcctacg gcgccatgcg
    10921 ccgcctgacc gacgagcgcg ggcggctcag gctggaccgg ctgcatccgt cctaggaagc
    10981 ggcggctttt ccggaaattt catgaaagct tgacgcgcgc ttggcgatac tgcgcgaaat
    11041 cttgcatttt cctgaacctt tcccggatcc ccatgccttt tgcttcccat tccgcggtgc
    11101 ccccgcagca gcttgcttcc gctcagcgcc gcctctctga gcgcgccttg ccggagcgcc
    11161 gggcatgagc gtttccatga ccgcatcgat ggcgcctgcg gcgcgccgcg ctgcctttcc
    11221 aggctggctg gtgctggcgt gcctggctct ctggctgggc gcgctggcct gggcccgctg
    11281 gctgaccttg cccgacgaag gccgttacgc cggagtggcc tgggagatgc tgcgcagcgg
    11341 ctcgcccatg gtgccgctgc ttgacggcat gccgtacttc cacaagccgc cgctgtatta
    11401 ctggctggcc cagatcagct atgtgctgtt cggcgtgcac gaattcagtg cgcggctgcc
    11461 gtcgctgctg ggcgcctgga gcgcgggcgc cgggctctat gccttcgtgg cgcgctaccg
    11521 caatgccgcg caagcgcgct gggccgtggt gatcctgggc atgatgccgc tgttcttcgg
    11581 cgccgcccag ttcgccaata tggacatgct ggtggccagc atgatcacgc tgtgcgtgct
    11641 ggcagccgcc gacaccgtct tgcgccgcgc cgcagggcgg ccgttccgcg cgatgtcggt
    11701 ggccacgggc gtgctggctg cgctggcggt gctggccaag gggctgatcg gagtggcgct
    11761 gcccggcgcc atcgtgctgg cctggctgct gctgcgccgc gactggcccg gcgtgcgcgc
    11821 cttgctgtgg gtgccagcct tgctggcgtt cgcggca
//
