LOCUS       NZ_HE978594.1          21362 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_HE978594.1 Peptoniphilus timonensis JC401, whole genome shotgun
            sequence.
ACCESSION   NZ_HE978594
VERSION     NZ_HE978594.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:50:22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 213533
            Orig. end    :: 234895
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21362
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[223533:224895](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11362)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..21362
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21362
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(558..1337)
                     /locus_tag="ctg2_232"
                     /transl_table=11
                     /translation="MGKTPQDDSHNKSRNLGYVVDSLSILLLIISLVQVRFSILNIKIL
                     LIISAVILLIQTVAIYYRNYYFDLGNKDRFNMFLDNSFGRKIIPCYNSDEYFDNKDIEA
                     GFIKALANTHQNSFFTSNLAKLNKKSYYVFSFIVLFLFVYAVFINGLNDTTSLLLNFIV
                     SGEIINKAIKYNSLYDKTNNIYESCNRICSSYQTNNQEKFFADIFEIIISYENIIYESK
                     IELSQKIFLKNNLRLTLEWEKIKDDYKIYSKSREIKE"
     CDS             complement(1616..1978)
                     /locus_tag="ctg2_233"
                     /transl_table=11
                     /translation="VNNIREQINDLLKQQTELQVNYKESNICIYGKYHYSLKHNDVILD
                     GVKDIKIEMDYEYPISIPKVYIFNLKEELEHVYKDNSICLATVGEILQYLIDKPSISEF
                     LNRFFRSVYIFGRLAS"
     CDS             complement(1971..2660)
                     /locus_tag="ctg2_234"
                     /transl_table=11
                     /translation="MTEIVNSGVDLNYVFKTVSITEKEDSNYSWLTSNPLGFGDWFKDI
                     SERFISTEMKMEQFHNFPVELREIYNKVENIPNYYYRSNLQRAVQVVKRHRDIFYDRSR
                     NVKSKPSSILITALIADSVKDEFNLSIIDIIKVFIHKFKNKQISIMVDNKILNPVDLRE
                     DFISSISESEKNIMNSWIADLSNFISIDSEVEFKKSIHNDFNSKMYSDAFYNVNIVNPT
                     KPWRYSE"
     CDS             complement(2795..3082)
                     /locus_tag="ctg2_235"
                     /transl_table=11
                     /translation="MEKRDKLLIESLNDIDITPTMEKNAREKYKAISEYLNGHDLESDF
                     YPQGSFLLGTVIRPYRDGKDKNYDLDILALLKKKNQIQIHKVQKMMLVIV"
     CDS             complement(3097..4017)
                     /locus_tag="ctg2_236"
                     /transl_table=11
                     /translation="MSKLEEAKELLKEMQVPERQQSDLCGYVILALANIKDKDLWCNAT
                     NNWIRIHDIILFISENYGLAYAENSRETFRKQAIHHFRNAAFIEDNGKATNSPNYRYRL
                     TDEMLGLVKTYKTDDWEKCKLDFLSNHDTLMDLYKSKKSMKKMPVNINGNEFKFSPGKH
                     NQLQKLIIEEFAPRFAENSECLYVGDTIQKDLVKNEEKLKELGFEITLHDKMPDVVLYS
                     EDKDWIYFIESVTSVGHMTPKRMLEIEEMTKDVKSGKIYVTAFLDFKTFKRFSDSLAWE
                     TEVWIADLPDHMIHLNGDKFLGPRK"
     PFAM_domain     complement(3121..3576)
                     /aSDomain="BsuBI_PstI_RE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06616.13"
                     /description="BsuBI/PstI restriction endonuclease domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_236_0002"
                     /evalue="1.60E-59"
                     /label="ctg2_236"
                     /locus_tag="ctg2_236"
                     /protein_end="299"
                     /protein_start="147"
                     /score="199.8"
                     /tool="antismash"
                     /translation="PVNINGNEFKFSPGKHNQLQKLIIEEFAPRFAENSECLYVGDTIQ
                     KDLVKNEEKLKELGFEITLHDKMPDVVLYSEDKDWIYFIESVTSVGHMTPKRMLEIEEM
                     TKDVKSGKIYVTAFLDFKTFKRFSDSLAWETEVWIADLPDHMIHLNGD"
     PFAM_domain     complement(3613..4017)
                     /aSDomain="BsuBI_PstI_RE_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17728.3"
                     /description="BsuBI/PstI restriction endonuclease HTH
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_236_0001"
                     /evalue="1.00E-39"
                     /label="ctg2_236"
                     /locus_tag="ctg2_236"
                     /protein_end="135"
                     /protein_start="0"
                     /score="135.7"
                     /tool="antismash"
                     /translation="MSKLEEAKELLKEMQVPERQQSDLCGYVILALANIKDKDLWCNAT
                     NNWIRIHDIILFISENYGLAYAENSRETFRKQAIHHFRNAAFIEDNGKATNSPNYRYRL
                     TDEMLGLVKTYKTDDWEKCKLDFLSNHDTLM"
     CDS             complement(4030..5502)
                     /locus_tag="ctg2_237"
                     /transl_table=11
                     /translation="MKIIDYVLNKTNEYIKIASKETRKRIGQFFTSKEAAIFMASLFDL
                     NIKRDEISILDPGAGSGVLSAALIQRIIDSKMIKKINLTCYETDEDIVNLLEANLYWVK
                     ENSNIDIEYRIIDKNYIISQDYEYNNFLGMYNNVKKYDLVICNPPYKKIGKKDREAIIM
                     SDVCYGSPNLYFLFMQMSNFNLKENGELVFIVPRSWTSGAYFKKFREEFLEEMSLEHIH
                     LFTSRDKVFDKESVLQETMIIKAKKTRIPPEFITITSNNGNFDFKNTTIFEADYDLVVS
                     KKNKYIYLITNEEEANTIKQVKEWKDTLPSLGLKMKTGLTVDFRNSEVLRDRSEEEAVP
                     LFYSQHIKDGKVVFPMGKDNEYILNSKKGLLQENKNYLFVKRFTSKEEKRRLQCGVYLA
                     KKYPEYEKISTQNKLNFITGFENLSECLVYGLYVVLNSTLYDQYYRILNGSTQVNSTEI
                     NSMPVPPLEYIENMGKDLIKVKICQKKHVMKY"
     PFAM_domain     complement(4789..5085)
                     /aSDomain="Eco57I"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07669.13"
                     /description="Eco57I restriction-modification methylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_237_0003"
                     /evalue="1.40E-12"
                     /label="ctg2_237"
                     /locus_tag="ctg2_237"
                     /protein_end="238"
                     /protein_start="139"
                     /score="48.1"
                     /tool="antismash"
                     /translation="KYDLVICNPPYKKIGKKDREAIIMSDVCYGSPNLYFLFMQMSNFN
                     LKENGELVFIVPRSWTSGAYFKKFREEFLEEMSLEHIHLFTSRDKVFDKESVLQ"
     CDS             complement(5489..5704)
                     /locus_tag="ctg2_238"
                     /transl_table=11
                     /translation="MLKISYKKLFKKMIDLDLNNTELMEKTNISRSTFYKMKNGENITT
                     DVLLRICEGLNCNLYEIMELVKDENN"
     PFAM_domain     complement(5501..5683)
                     /aSDomain="HTH_26"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13443.8"
                     /description="Cro/C1-type HTH DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_238_0004"
                     /evalue="3.50E-14"
                     /label="ctg2_238"
                     /locus_tag="ctg2_238"
                     /protein_end="68"
                     /protein_start="7"
                     /score="53.1"
                     /tool="antismash"
                     /translation="KLFKKMIDLDLNNTELMEKTNISRSTFYKMKNGENITTDVLLRIC
                     EGLNCNLYEIMELVKD"
     CDS             complement(5973..6131)
                     /locus_tag="ctg2_239"
                     /transl_table=11
                     /translation="MLKQVLDIIILYLLIYLFGAYIIFLVKSVIYGKEKVYGCSKPTLM
                     EKIFIGC"
     CDS             complement(6263..6856)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 61.4; E-value: 1.6e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg2_240"
                     /transl_table=11
                     /translation="MKIILLDDHKLFGGSLKMLLEEQEEISCAYVSKAQEFLKMIEKEI
                     YDIFLIDINLKDDKTGLDLIKYLIDENPRQKIIVLTSYDLDNYKDMAFKLGVKDFINKS
                     VEIEELLARINNVYKGNYKKIDKYIVDPLTKREIEVLEELIKGSSKKDIAKKLFISERT
                     LYNHIANIYDKLQSKNIVEAYNKAMELGYIYPVM"
     PFAM_domain     complement(6299..6466)
                     /aSDomain="GerE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00196.21"
                     /description="Bacterial regulatory proteins, luxR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_240_0006"
                     /evalue="5.20E-18"
                     /label="ctg2_240"
                     /locus_tag="ctg2_240"
                     /protein_end="186"
                     /protein_start="130"
                     /score="64.5"
                     /tool="antismash"
                     /translation="DPLTKREIEVLEELIKGSSKKDIAKKLFISERTLYNHIANIYDKL
                     QSKNIVEAYNK"
     PFAM_domain     complement(6512..6850)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_240_0005"
                     /evalue="2.60E-19"
                     /label="ctg2_240"
                     /locus_tag="ctg2_240"
                     /protein_end="115"
                     /protein_start="2"
                     /score="69.6"
                     /tool="antismash"
                     /translation="IILLDDHKLFGGSLKMLLEEQEEISCAYVSKAQEFLKMIEKEIYD
                     IFLIDINLKDDKTGLDLIKYLIDENPRQKIIVLTSYDLDNYKDMAFKLGVKDFINKSVE
                     IEELLARIN"
     CDS             complement(6837..7994)
                     /locus_tag="ctg2_241"
                     /transl_table=11
                     /translation="MYKKLEKIVISHLMIILFWGLLFKNNLLVKEGPILNAVSLILFFT
                     LYGLIYTEISNKKIPEFVSILVVFTSLLPLSLILINNLHYKVSFAIISIASTCLFIKKY
                     MDIESFKYINILPISRKSTQTFTIKLVFFIFVVIYLFDIDTAMINIFTQIVFLITEFFF
                     ILFLKEKELAFEKTFKLYYLSDYMASERDEFARIIHDDILQDIYASKNYLSSKNPDIEY
                     SKNILRELEEKARNIMKFYQSSLFEKANLETSLLAIFDNVASLYPDKNIEITKYIDSDM
                     TEDKRLIRLISIISKELINNVYKHSDAKYLSYKLYKKGNFVYIEMESDGARSDDFNKIK
                     ESKRGVLLLKLLIDSNSGNISYGLNKGILTTRVSLEVEKDENYFA"
     CDS             complement(7997..8635)
                     /locus_tag="ctg2_242"
                     /transl_table=11
                     /translation="MKLVINDLKKLLDKNALLMSLMALICSFMALFFADGGSQEINKVI
                     DTIKIDGILILFVMFGVELAKNTLVSDKISKKLEFLLANGLSIKKILAKYLFSIYLGAL
                     IIVLPSLVLNLVKLDLSLTIGINLILSSFLYTLIIVFVILNTRNMNKINSLQIRLIGLS
                     LAIMITSAIVYNFTNSFTFYFLTKFIILASIIIFLGININKERIVISYY"
     CDS             complement(8632..9345)
                     /locus_tag="ctg2_243"
                     /transl_table=11
                     /translation="MKNKMNINRACRYYLSKDKDFILNLLLSTLISLGFIFLLYKGMFD
                     SRGNDYIILMLYVLMLGISLIMSNSMVVNLTVKDKLNKRIEFILASGINIKDVIKAYAI
                     EMWRLSSIVPFLLFFLTYVLVDFKIEFKWIVGIFVTMIGMTYFEILFFNLISLSQKNFK
                     FFKNIVFFGTTILIYMIGTFSEKILSLIERYNLNLIYIILGINIGLGLIFAVFSMKDLS
                     KINNESIINKEGSWS"
     CDS             complement(9342..10004)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 137.7; E-value:
                     8.4e-42)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_244"
                     /transl_table=11
                     /translation="MNVIEVKNMSQNFKNKKLFNSFSLEIEENTVHAIVGPNGSGKTSL
                     LRILTNLYYEDNGKVIVKGNHAMLLENDYLYEDKTGIENIKLYGLYFGYEPINYKKYSE
                     LLQITNDLDRKVSTYSKGMKRKLSLLIIVMMNREIIFLDEVTSGVDPISRVEIRKLIKL
                     LKDEGKTIVITSHDLSEIEKIADKVSMIKSGELLFTKNIGEIKGESLEDLFIEEGTK"
     PFAM_domain     complement(9564..9947)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_244_0007"
                     /evalue="1.00E-18"
                     /label="ctg2_244"
                     /locus_tag="ctg2_244"
                     /protein_end="147"
                     /protein_start="19"
                     /score="68.3"
                     /tool="antismash"
                     /translation="NSFSLEIEENTVHAIVGPNGSGKTSLLRILTNLYYEDNGKVIVKG
                     NHAMLLENDYLYEDKTGIENIKLYGLYFGYEPINYKKYSELLQITNDLDRKVSTYSKGM
                     KRKLSLLIIVMMNREIIFLDEVTS"
     CDS             complement(10001..11362)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_245"
                     /sec_met_domain="PF04055 (E-value: 2.8e-15, bitscore: 51.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5.4e-07, bitscore: 24.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5.6e-22,
                     bitscore: 72.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 1.1e-07,
                     bitscore: 26.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VYLKAKNIKAIEKQKNANILVVENRYEKMGESLYRINNDATNIIL
                     WLDGNHTFDEIAKKMCDNNTSLIEEAKINLNEFLNSLILNYGIVIDRLENPRYDEIRVL
                     GNGKTQYPSAISIEITHTCNVKCLHCYGEYSCYNKFKDNTESIFKVLEDARRSGTRVVE
                     FTGGEVTCHPRFLDILDKAYSLNYHLVSILSNGTNWNEDLFNEIYKNRDKTVVQIDLHG
                     DNDDYINWFMGSRIKNISNIIKSNIVRIHKMGIYMRIVTMITPNNIDQLENIADWIHEN
                     GIETYGLSSIIPMGRAALKDNNNLLLKTKEDSEKLNEVISKINNKYGYGFLYQVKDGDP
                     NVKNCGAFTRNPSITPEGDIKFCAMDDQTLIKSFGNVFNTDIGKLYTENYKILDLIRNI
                     EAPSYVNSECENCEKKFFCSECIIRGLIGAKEIGVENCAWFYNKLNDEFRRLLI"
     PFAM_domain     complement(10529..11014)
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_245_0008"
                     /evalue="9.70E-14"
                     /label="ctg2_245"
                     /locus_tag="ctg2_245"
                     /protein_end="278"
                     /protein_start="116"
                     /score="52.2"
                     /tool="antismash"
                     /translation="IEITHTCNVKCLHCYGEYSCYNKFKDNTESIFKVLEDARRSGTRV
                     VEFTGGEVTCHPRFLDILDKAYSLNYHLVSILSNGTNWNEDLFNEIYKNRDKTVVQIDL
                     HGDNDDYINWFMGSRIKNISNIIKSNIVRIHKMGIYMRIVTMITPNNIDQLENIADWI"
     CDS             complement(11574..11699)
                     /locus_tag="ctg2_246"
                     /transl_table=11
                     /translation="MKPEIVAMGNGCKLCAGCTGCMFCGPSPAAGVGVAGFVGFF"
     CDS             complement(12575..13252)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 147.8; E-value:
                     6.9e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_247"
                     /transl_table=11
                     /translation="MGIIKIKNINKKFKQNVLYENASLEIEAGKTIGIVGGNGTGKSVL
                     FKMITGLEFVDDGEIYVRDKKVGKDLDFPRNVGLFVNQPGYIDFYDGFTNLKLLADIQG
                     KIDDSTIKEYMKRVGLDPDNRSRVKTYSSGMKQKLGIAQAIMENQDIILLDEPFNALDF
                     QTNVDVLKILSALKNEGKTILLTSHQHEYLEKICDEIYMILDKKFVLFTDELKKSYFSV
                     FEK"
     PFAM_domain     complement(12776..13195)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_247_0009"
                     /evalue="2.30E-25"
                     /label="ctg2_247"
                     /locus_tag="ctg2_247"
                     /protein_end="159"
                     /protein_start="19"
                     /score="89.8"
                     /tool="antismash"
                     /translation="ENASLEIEAGKTIGIVGGNGTGKSVLFKMITGLEFVDDGEIYVRD
                     KKVGKDLDFPRNVGLFVNQPGYIDFYDGFTNLKLLADIQGKIDDSTIKEYMKRVGLDPD
                     NRSRVKTYSSGMKQKLGIAQAIMENQDIILLDEPFN"
     CDS             complement(13233..14747)
                     /locus_tag="ctg2_248"
                     /transl_table=11
                     /translation="MGRKCKRIFVENRTLLLINFGVLCFLCGSIIRKYRKVDMGIWGYM
                     LSILTNHYYILYCVFPILLIIIARHIRNVNDIEMIRYRNAFQQIKMSTKSFIQWLMAYM
                     VLHLVITFVIGIRTFDLSIHTQNIKVETYDELINILNTYIEYFSNSLFAVISNVVYFLF
                     GFTVLISLLSYINYRYKYRNVILSSVLIYILTFIGFKTELKAIIPIVCFDNFILLHHGL
                     FVNGSAKFLLTILFGVLVIQFCFGRMFKVNKYGFKEFIISKKEKYISALVVLVLFLLEL
                     LRKIGNVDFNFKDVIIMTLFGTNEKYVSFIPWLRITILYLIPLFFIGIADSRIKKYGQA
                     PILIRTKSKLSFEHKLIGVYMNYIFLYTLFVYALGSVFYFMGGAGTLSNEYFISEFNIK
                     FTYGILSMYFVIFLVNLTFDFVIFKILCKFANGIVSFLAILFFKFFFFMLPTFNLFDLN
                     FGLSNLFDGINNKNELVIKVATICVLNVIFFAIINMRRIRHGNYQD"
     CDS             complement(14731..15486)
                     /locus_tag="ctg2_249"
                     /transl_table=11
                     /translation="MRLYLSSMRKQAIPAFAVGIIYAVVLMTLIVIYNSNSMIYYQISP
                     YSYASEPIDFFFGLIVSIPFSIYTFFMKKDNFLEYVHVRISRKKYILIHILSTMAVCFL
                     MVFIVNIIGVVFSCNIADLVETGNKPTLANYIFGELQMYNPIAFGILWSLQKALIGTII
                     CLFGQITALYIENLFLALIAPFAYIIVENFITSILGLSRFSITTTFVLNRLKPRSMTIT
                     NITIGSICFILIIAIIGTVLRSRFNGEKV"
     CDS             complement(15656..15970)
                     /locus_tag="ctg2_250"
                     /transl_table=11
                     /translation="LKKIKTLLAVFAIFIFGSMMVYAGTTYEGYNTTVGRLNGNGYTAY
                     QTKYIGGANGDLSSDYVGSDYVVDARMQEDDGTAGSWTRDVDDNSYYDLDGHIDHKYGD
                     "
     CDS             complement(16213..16329)
                     /locus_tag="ctg2_251"
                     /transl_table=11
                     /translation="MNKIETEKTPHTLNTANDIADTLGICMYQVFDLDGKGL"
     CDS             complement(17019..17258)
                     /locus_tag="ctg2_252"
                     /transl_table=11
                     /translation="VYGGRLPVHVRCLLDEFANIGLIPKFEKLIATIRSREISASIILQ
                     AQSKLKAIYKDHADTIVGNCDLTLKEITTVKEFI"
     PFAM_domain     complement(17055..17234)
                     /aSDomain="TraG-D_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12696.9"
                     /description="TraM recognition site of TraD and TraG"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_252_0010"
                     /evalue="2.00E-19"
                     /label="ctg2_252"
                     /locus_tag="ctg2_252"
                     /protein_end="68"
                     /protein_start="8"
                     /score="69.9"
                     /tool="antismash"
                     /translation="HVRCLLDEFANIGLIPKFEKLIATIRSREISASIILQAQSKLKAI
                     YKDHADTIVGNCDLT"
     CDS             complement(17688..17954)
                     /locus_tag="ctg2_253"
                     /transl_table=11
                     /translation="MKKIIHLLFLCLISVFVFFCIEYVVYKFFILHNPLYIVTFILFLV
                     VFYLDIHLLNKMNFPYKIISPTIALITVFLGLALLKFLLPILK"
     CDS             complement(18339..19127)
                     /locus_tag="ctg2_254"
                     /transl_table=11
                     /translation="MTKCFKKCLSLLLAIVLCMGTTITAFAAEERDPYTIEGHYVEELV
                     QLNEEELANLPLEQAETLFEEAFAVPADNYTEDEIRLGLDGLSFGLKFQLIMDEIKKTA
                     DTEPSYPVKTRSTTGSVSYSGDIGVAWVRDTTSGHSPLTLGEILSGTYTLEVDFITWDT
                     AAAILASSASYDAFKDLVELVGTGAAGSALGAYICSXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLL"
     CDS             complement(19425..19826)
                     /locus_tag="ctg2_255"
                     /transl_table=11
                     /translation="MFWMSNTFLTDYNKSIVKRTAGLLLIIILMVNLSSCSSSNDIIID
                     KENNGESVKVYIYDEKQEGFKELDISSDQQRKVLEELNKLNKDCNLYDSNNQYLGLDIA
                     YSDGAYLIKIKNDEEYEIEIVEDNPISAE"
     CDS             complement(20150..20398)
                     /locus_tag="ctg2_256"
                     /transl_table=11
                     /translation="MDTWFGPVHDGFTVRLKDMSCSGGISYSVIIEEDGKIIYDERFAS
                     DSTLKVKAYRGSKYIVTIINQTNTTLSGKIKINSYVR"
     CDS             complement(20700..21356)
                     /locus_tag="ctg2_257"
                     /transl_table=11
                     /translation="MEYKDIRENLEEMMNDNYKDFIKALVSIEKGVNDEKALEEVYVLY
                     MNNDITGLLSDDFDYMIDDMKEQGKIVENVSDIEEKDDLINLVGNIAGKVENLERENSH
                     GEKFKVSNFSIVSKDDDGNKIYTNCSAYGDKTKDLENLKQGDFVKIFGQVKTSIDNNGK
                     EHKNVRILSSKLLKAKEQVKSQDKDKKSILGQIKSFKTDDKTKSNKKDHSKGAER"
ORIGIN
        1 aaaaacgtgt aggaaatgtt attgatatat ctactaatga aaaagctcaa tcctctaaag
       61 gttatgaagt ttgggcaaga aaacataata tcaaaacaat ggctgattca ataattaaac
      121 ttagagaaca aggaattaat tcaatcactc aactcgatga tctaattaaa aaatctgctg
      181 atgatagaca agacttatta gataaaataa agaagattga aactgaaatg aagagtttat
      241 ctcaagatat ggaaaatata aatactataa ataagtatcg tgaaatatat aaataccaca
      301 agaaaaatcc tgaagataag caatttgcag atgagtatta tagtgaactt tccgtctata
      361 aaatagccgc aaaagaaatt ttagaaaact ataaaaaact accaaacaca aaagaaatac
      421 tatcaaacct cgataaattg caagaaaaaa agaacaccct tatgcaagag tattctttga
      481 ataaagagca attttctgac cttgttcagt ataggaaaaa ctatgaaaat tattatggaa
      541 aggaggtgga gagataatta ctctttaatc tctctacttt ttgaataaat tttataatca
      601 tctttaatct tttcccattc caaagtgagt cttaagttgt tttttaaaaa tattttttga
      661 gaaagttcaa ttttactctc ataaattata ttctcataac taattattat ttcaaaaata
      721 tctgcgaaaa atttttcttg attatttgtt tggtaagatg agcatattct attacatgat
      781 tcgtaaatat tattagtttt atcataaaga gagttatatt ttatagcctt attaataatc
      841 tcacctgata ctataaaatt aagcaataaa gatgttgtat catttaatcc attgataaaa
      901 actgcatata caaataaaaa taaaacaata aaagaaaaaa cgtaatacga ctttttattc
      961 agtttagcta aatttgatgt aaaaaaagaa ttttgatgtg tatttgctaa agctttaatg
     1021 aaaccagctt ctatatcttt attgtcaaaa tattcatcgc tattataaca tggtattatc
     1081 tttctaccaa atgagttgtc tagaaacatg ttaaatctgt ctttatttcc caaatcaaaa
     1141 taataatttc tgtaatatat tgctactgtt tgaattaata aaattacagc agaaattatg
     1201 agcaatattt ttatatttaa aatcgaaaat ctaacttgta ctaaggaaat tattaataat
     1261 aatattgata atgaatcaac tacataacct aagtttctag acttattatg actatcatct
     1321 tgtggtgttt tacccatatt ctttaccatc cttatttaat atcattatag attctattaa
     1381 aaaggtattt cttaatcttt gatttttaac aattggaagt atatatctac catggcaatt
     1441 tctcaattta aaacccgaat tgcaaaaaca aggtaaatga cctttgtatt tattatggta
     1501 aattaaaaat accattttaa tgtactgttc ttttgttaat ccccactctt ccgtataata
     1561 acttaataaa ccctcatatc catgtttcct ttccccaaat ggaaatactc catatttaag
     1621 atgccaatct gccgaaaata taaacggatc taaaaaatct atttaaaaat tctgaaattg
     1681 agggtttatc aataagatat tgaagtatct ccccaacagt tgctaagcaa atactattat
     1741 ctttatatac atgttctagt tcctctttta agttgaagat atatactttt ggaatactaa
     1801 tgggatactc ataatccatt tctattttaa tatccttgac cccatctaaa atcacatcat
     1861 tatgttttaa ggaataatga tattttccgt atatacatat atttgattct ttgtaattta
     1921 cctgcaattc tgtttgttgt tttaataagt cattgatttg ctctcttata ttattcacta
     1981 tatctccatg gcttcgttgg gtttacaata tttacattat aaaacgcatc tgagtacatc
     2041 tttgaattaa agtcattatg aatagatttt ttaaattcta cctctgaatc tatacttata
     2101 aaatttgata agtcagctat ccaactattc ataatattct tttccgattc agatatacta
     2161 cttataaaat cttctctcaa atcaacagga tttaaaattt tattatctac cattatagat
     2221 atttgcttgt tcttgaattt atgaataaac acttttatta tatctataat agataaattg
     2281 aactcatctt taacagagtc tgctatcaaa gctgttatta aaatagaaga tggcttagat
     2341 ttaacattcc tacttctatc ataaaatata tccctatgtc tttttacaac ctgtactgct
     2401 ctttgtaaat ttgatctata atagtaattt ggtatattct ctactttatt atatatttct
     2461 cttagttcga caggaaaatt gtgaaactgt tccattttca tttctgttga aataaacctt
     2521 tcgctaatat ctttaaacca atcaccaaat cctaaaggat tgctagtcaa ccatgaataa
     2581 ttactatctt ctttctcagt tattgataca gtcttaaata cataatttaa atctacacct
     2641 gaattaacaa tttcagtcat aatattttct tcctcattaa cacaaggaac aatatctaga
     2701 ttaaatccta ctccccctga tacctctgca tactctaaag tccagcagtt tttatcttct
     2761 tttgataatt tagacttata taattcacta ctttttatac aatcaccaac atcatttttt
     2821 gtactttgtg gatctgtatt tgatttttct tttttaataa agctaaaata tctaaatcgt
     2881 aattcttatc ttttccatct ctatatggtc ttatgacagt tcctaacaaa aaagaacctt
     2941 gtggataaaa atcagattca agatcatgcc catttaaata ctcagaaata gccttgtatt
     3001 tctctctagc atttttctcc atagttggag taatatcaat atcattaaga ctttcaatca
     3061 acaatttatc tcttttttcc attctattat taccccctat tttctcggtc ctaaaaactt
     3121 atctccattc aaatgaatca tatgatcagg taaatcagca atccacactt ctgtttccca
     3181 tgccaatgaa tcagaaaacc tcttaaaagt tttaaagtct aaaaatgcag ttacatatat
     3241 tttccctgat ttaacatcct tagtcatttc ttcaatttct aacatccttt taggtgtcat
     3301 gtgtccaaca gatgttactg actcaataaa gtaaatccaa tccttgtctt cagaatacaa
     3361 aactacatca ggcattttat catggagtgt tatctcaaaa ccgagttctt ttagtttctc
     3421 ctcatttttt accaaatcct tttgaattgt gtcaccaaca tataaacatt cagaattctc
     3481 agcgaatcgt ggagcaaatt cttcaataat tagcttttga agttgattgt gcttgcctgg
     3541 tgaaaattta aattcgtttc catttatatt tactggcatt ttcttcatgg attttttaga
     3601 tttatacaaa tccattaaag tatcatgatt acttaaaaag tctagtttgc atttttccca
     3661 atcatcagtc ttatatgtct ttaccaatcc taacatttca tctgttaacc tatatctata
     3721 attcggacta tttgtcgctt ttccattatc ttctataaaa gcagcatttc taaagtggtg
     3781 tattgcctgt tttcgaaatg tctctctact attttcagca tatgcaagac cataattctc
     3841 cgatataaat aatataatat catgtatcct tatccaatta ttagttgcat tgcaccataa
     3901 atctttatcc ttaatattag ctagagccaa tataacatat ccacataaat ccgactgttg
     3961 tctttctggt acttgcattt cctttaaaag ctcttttgct tcttctaatt tagacataaa
     4021 tatacctccc taatatttca tcacatgttt tttctgacat atctttacct ttatcaaatc
     4081 ttttcccata ttctcaatgt attctagtgg aggaactggc atagaattaa tttctgttga
     4141 attaacttga gttgaaccat ttaaaattct ataatactga tcatataaag tggaatttag
     4201 aaccacatat aatccatata ctaaacactc agataaattt tcaaatccag ttataaaatt
     4261 taatttattt tgagtgctta tcttttcata ctctggatat ttttttgcta aatagactcc
     4321 acattgtagt cgtctctttt cttctttaga tgtaaatctc tttacaaata aataattttt
     4381 attctcttgt aataacccct tttttgaatt taaaatatat tcattatcct tacccattgg
     4441 aaaaacaact tttccatcct ttatatgctg agaatagaat aagggtactg cttcttcttc
     4501 agatctatct ctcaatactt cactatttct aaaatccaca gttaatcctg ttttcatttt
     4561 taatcccaag cttggcaaag tatctttcca ctcttttact tgttttattg tatttgcttc
     4621 ttcttcattt gtaattaaat atatatattt atttttttta gaaacaacta aatcataatc
     4681 tgcttcaaaa attgttgtat ttttaaaatc aaaatttcca ttattagatg tgattgttat
     4741 aaattcaggg ggtattcttg tctttttagc ctttattatc atagtttctt gtaagacaga
     4801 ttctttatca aaaaccttat ctctactcgt aaataaatgt atatgctcca atgacatttc
     4861 ttctaaaaat tcttctctaa attttttaaa gtatgctcca gatgtccaag atcttggaac
     4921 aataaatacc agttccccat tttcttttag attgaaattt gacatttgca taaaaagaaa
     4981 atataaatta ggagaaccat aacaaacatc tgacattata attgcttctc tgtctttttt
     5041 accaattttc ttatatggtg gattacatat aactaaatca tattttttaa cattgttata
     5101 cattcctaag aaattattgt attcataatc ctgacttata atataattct tatctataat
     5161 tctatattct atatctatat ttgaattttc ctttacccaa tataaattag cttccaacaa
     5221 atttacaatg tcttcatctg tttcataaca tgttaaattt atctttttta tcattttgct
     5281 atcaataatt ctctgaatta gtgccgcaga aagaactcca gagccagctc ctgggtcaag
     5341 aatagatatc tcatctcttt taatatttaa gtcaaataaa gatgccatga atattgctgc
     5401 ttctttacta gtaaaaaatt gtcctattct ttttcgagtt tctttagatg caatcttaat
     5461 atattcattt gtcttattta aaacataatc aattattttc atctttaact aactccataa
     5521 tttcgtaaag attacaattt aatccttcac atattcttaa caatacgtca gttgtaatat
     5581 tctccccatt tttcatttta taaaatgtac ttctactaat atttgttttt tccattaatt
     5641 ctgtattatt taaatctagg tcaatcattt ttttaaatag ctttttatag ctgattttta
     5701 acatgactat ctctccattc atgaattctg tatcagttat attatatcat aaaccttcac
     5761 ttttttcata atattattca cttttctaaa acataaatac aaaaaaaata aaggcagtcc
     5821 gaagaccacc aatatttgtg ttttccacca aatttctatc tttttgctgc ttctatactg
     5881 ttaatttaat ataagctact gcaaaatttt aataagagta caatcctatc aaatttaaaa
     5941 tcaatattaa tttttaaagt atgaaacact tgttagcatc ctataaaaat tttttccatt
     6001 agtgtaggct ttgaacaacc ataaactttt tcttttccat atatcacaga cttcactaga
     6061 aaaataatat atgctccaaa caaatatatt agtaaatata aaattattat atctagaact
     6121 tgttttaaca taaacatccc tcactttttt tatttctacg attataataa gttggcaaga
     6181 tgtttaatct cagtttttat atctatgaga gttttcataa atcataaaat ataatctcca
     6241 aataagtttt aatcatataa tcttacataa ccggatatat atagccaagc tccatagcct
     6301 tattataggc ttcaacaata tttttagatt gtaatttatc atatatattt gctatatgat
     6361 tataaagggt cctctcactg ataaaaagct tcttggcaat atcttttttg cttgacccct
     6421 ttattaattc ttccagtact tctatctctc gtttagtcag tggatcaaca atgtatttat
     6481 ctattttctt atagtttcct ttatatacat tatttattct tgctaagagt tcttctattt
     6541 caacagactt atttataaaa tcctttactc ctaacttaaa agccatatcc ttgtaattat
     6601 ctaagtcata agatgttaaa actattatct tttgtctggg attttcatct atcaaatatt
     6661 taattaaatc aagaccagtc ttatcatctt ttaaatttat gtcaattaag aaaatatcgt
     6721 agatttcttt ttctatcatt tttaaaaact cttgggcttt tgatacatag gcacatgaaa
     6781 tttcttcttg ctcttctaaa agcatcttaa gagatccacc aaataattta tggtcatcaa
     6841 gcaaaataat tttcatcttt ttccacctcc aagctaactc ttgttgtaag tattcccttg
     6901 tttaatccat aggaaatatt tcctgaattt gaatctatca aaagtttaag cagcaaaacc
     6961 cctcttttag attccttaat cttattaaaa tcatctgatc ttgcgccatc actttccatt
     7021 tctatatata caaaatttcc ttttttataa agtttataag ataaatattt agcatcggaa
     7081 tgcttatata cattatttat aagttctttt gatattattg aaatcaacct aattaatctt
     7141 ttatcctctg tcatatcact atcgatatat ttagtaattt caatattttt atctggatat
     7201 agtgaagcta cattatcaaa tatagctaat agagatgttt ccaaatttgc tttttcaaat
     7261 aaagaagatt ggtagaattt cattatattt cgtgcttttt cctcaagttc tcttaggata
     7321 tttttagaat attctatatc aggatttttt gaagataagt aatttttact tgcatatata
     7381 tcttgcaaaa tatcgtcatg aataattctt gcaaattcat ctctttcgct cgccatatag
     7441 tctgataggt aataaagttt gaaggttttc tcaaaagcta actctttctc ctttaaaaat
     7501 aagataaaga aaaattctgt aataagaaaa actatttgag taaatatatt tatcattgcc
     7561 gtatctatat caaataagta aattaccaca aaaataaaaa atactagttt gatagtaaat
     7621 gtttgtgtag attttcttga tattggtaag atgtttatat atttaaaact ctctatatcc
     7681 atgtattttt taataaacag gcatgttgaa gcaatactaa taatggcaaa ggagacttta
     7741 tagtgtagat tatttattaa aataaggctc aacggcaaaa gagaagtaaa aacaaccaaa
     7801 atggaaacaa attccggtat ttttttattc gaaatttctg tgtatataag tccatacaag
     7861 gtgaaaaata atataagtga aactgcattt aaaattgggc cctcttttac taacaaattg
     7921 tttttaaaaa gaagacccca aaataaaatt atcattaaat ggcttattac aattttttct
     7981 aatttcttat acatatctaa tagtaactaa ttacaatcct ttctttatta atattaatac
     8041 ccaaaaatat aataattgaa gctaagataa taaacttagt aagaaaataa aatgtaaagg
     8101 agtttgtaaa attatataca atggcagatg ttatcataat agctaaagat agtcctatca
     8161 accgaatttg gagagaattt attttattca tgtttctagt attaagaatt acaaaaacta
     8221 ttattagagt gtaaagaaaa cttgataaaa ttaagtttat accaatggtt aagcttagat
     8281 caagtttaac taggtttaat acaaggcttg gaaggactat tatcaaagcc cctaaataaa
     8341 tactaaacaa atatttggct agaatttttt ttatagaaag tccatttgca agtaaaaatt
     8401 caagtttttt gctaatctta tctgatacca aggtattttt agcgagttct actccaaaca
     8461 ttacaaaaag tattaaaatt ccatcaattt taattgtatc gatgacctta tttatctctt
     8521 ggcttcctcc atcagcaaaa aatagagcca taaaggagca gattagtgcc ataagagaca
     8581 ttaataaggc atttttatct aaaagctttt ttaaatcgtt aatgactaac ttcatgacca
     8641 tgacccttct ttattaatta tagattcatt gtttatctta gacaaatctt tcatagaaaa
     8701 aactgcaaag attaatccta agccaatatt tatacctagt atgatataaa taagatttag
     8761 attatatctt tctattaatg atagaatctt ctctgaaaaa gtgcctatca tgtaaattaa
     8821 aattgttgtt ccaaagaaaa ctatattttt gaaaaactta aagttttttt gggataaact
     8881 tataaggtta aaaaatagta tttcaaaata tgtcattcct atcattgtaa caaatatgcc
     8941 tacaatccac ttaaattcga ttttaaagtc tactaggaca taagttagga aaaataataa
     9001 aaatggaaca atagaagata gtctccacat ttctattgca taggctttaa tcacatcttt
     9061 tatattaatt cctgatgcta gaataaattc aatacgttta tttagtttat ccttgactgt
     9121 aagatttaca accatagaat tagacataat taatgaaatt ccaagcatta gtacatatag
     9181 cattaatata atataatcat ttcctctaga atcaaacatc cctttatata gtaaaaaaat
     9241 aaagccaaga gaaatcaaag tagataataa taaatttaaa ataaaatcct tgtctttact
     9301 taaatagtac ctacaggctc tattaatatt catcttattt ttcattttgt accttcctct
     9361 ataaataaat cttctaagct ctctccctta atttctccaa tattctttgt aaaaagtaac
     9421 tctcctgatt taatcataga tactttatca gctatctttt caatttctga gaggtcatga
     9481 ctagtaatta ctatggtctt accttcatcc tttagtaatt ttatgagttt tctaatctca
     9541 actcttgata ttggatctac cccactagtt acctcatcta aaaatattat ctccctattc
     9601 atcattacaa taattaataa agataatttc cttttcattc ccttagaata tgttgatact
     9661 ttcctatcta aatcatttgt tatttgaaga agctcagaat attttttgta atttataggc
     9721 tcatatccaa aatataaacc atataatttt atattttcta ttccagtctt atcttcatac
     9781 aaataatcat tctctaaaag cattgcatga tttcccttaa cgataacttt tccattatct
     9841 tcataatata aattcgttaa tattctcaga agcgaagttt ttccagaacc attaggacct
     9901 actattgcat gcactgtatt ttcttcaatt tctaaagaaa aactgttgaa tagcttttta
     9961 tttttaaagt tttggctcat gttttttact tcgattacat tcatattaaa agcctcctaa
    10021 actcatcatt taacttatta taaaaccaag cacaattttc tactcctatt tcttttgctc
    10081 caatgagtcc ccttataatg cattcactac aaaaaaattt cttctcacaa ttttcacact
    10141 cggaatttac atagctaggt gcttctatat ttcttatcaa atctaatatt ttataatttt
    10201 ctgtgtatag cttaccgata tcagtattaa atacattgcc aaagcttttt ataagtgttt
    10261 gatcatccat agcacaaaat ttaatatctc cctctggagt aatagatgga tttcttgtaa
    10321 atgctccaca atttttaacg tttggatctc cgtcctttac ttgatataga aaaccatatc
    10381 catacttatt atttattttt gaaataactt cattcagttt ttcagaatct tctttagttt
    10441 ttaataataa attattattg tcttttaaag cagctcttcc cattggtata attgaagata
    10501 aaccataagt ctctatgcca ttttcatgaa tccaatcagc aatattttct aattgatcta
    10561 tattattcgg tgttatcata gttacaattc tcatatatat tcccattttg tgaatcctaa
    10621 ctatattgct ttttatgata ttcgaaatgt tttttattct agaacccata aaccaattaa
    10681 tataatcgtc attgtctcca tgtagatcta tttgtactac cgtcttgtcc ctatttttat
    10741 atatttcatt aaacaagtct tcattccagt ttgttccatt tgataaaata cttactaaat
    10801 gataatttaa agaatatgcc ttgtctaaaa tatcaagaaa tcttggatga caggtaactt
    10861 ctccacccgt aaattctact actctagtac cagatcttct tgcatcttct agtactttaa
    10921 atatcgattc agtattgtct ttaaatttat tatagcatga atattcacca taacaatgta
    10981 agcactttac attacaagta tgtgttattt caatagatat tgctgatggg tactgtgttt
    11041 taccatttcc taaaaccctt atttcatcat atctcggatt ttctaatcta tcaataacaa
    11101 tgccataatt gagaattaaa gaatttaaaa attcatttaa attaatttta gcttcttcaa
    11161 ttaagctcgt attattatca cacatctttt tagcaatttc atcaaatgta tgatttccat
    11221 ctaaccaaag tattatgttt gttgcatcat tatttattct ataaagagat tcacccattt
    11281 tctcatatct attttcaaca accaaaatat tggcattttt ttgtttttca attgctttta
    11341 tatttttagc ctttaaatac accttttcat atcccccgac ttaatactac atcctacaga
    11401 caaaactttt ttagctgtaa acttatcaaa agttattact agtctcaaaa caaatcgact
    11461 aaaaaactat aaaaaattaa ttatagtttt tttatttgtc atatttatat atgagactag
    11521 taaacataac tttttactct cattcttgtt atccaagaat ttcccccttc ttcttagaag
    11581 aatcctacaa aaccagctac acctacacca gctgctggac taggaccaca gaacatacat
    11641 cctgtacatc ccgcacatag tttgcaacca ttacccattg ctacgatttc aggtttcata
    11701 ttctcacctc cttacaacca tattttattt cattcttaat ttaattacat gagtaaatac
    11761 tgcaaattta caaaaaaata aaggcagtcc gaagactgcc aatatttatc tctctgcacc
    11821 tttgctatgg tctttcttgt tttatttagt tttatcttct gtcttaaagc tttttatttg
    11881 ccctaatatg aactttttat ctttatcttg aatctttact tgttcttttg attttaagag
    11941 cttagaagac aaaatacgaa catttttatg ttcctttccg ttgttatcaa tgcttgtttt
    12001 tacttgacca aatattttaa caaaatctcc tttttttaga ttctctaaat cttttgtctt
    12061 atctccataa gctgaacaat tagtataaac tttatttcca tcgtcatctt ttgaaacgat
    12121 tgaaaagtta cttacttcga atttttctca attagctttt tctctttcaa gattttcaag
    12181 ttttccagct ttactttctg gtgaaaaata atagatatca aatctataat tttgatcctc
    12241 tatttatctt gtaatcaacc ttaattttat taacagacac tctcttttca gaagttcttt
    12301 gtccttattt tccttttttt ctgcatttct tttcagctta ttttctttta attaagttgc
    12361 tttactctgt ttatgcattt tttcttttgt cttttttatc aaattgttcc atcaattttt
    12421 caaattttta aattgtcatt tcctcattct agctttttaa ataacaaaag caatcaagtt
    12481 ctcactcaat tgctttgcac ctaatcttta aactgtaatt actcaaattg cttattttag
    12541 catgtatatt accaccatca atccacaaaa tttctcactt ctcaaaaact gaaaaataag
    12601 actttttgag ttcatcggta aataacacaa attttttatc caaaatcata tatatttcat
    12661 cacatatttt ttccaaatat tcgtgttgat gtgaagttaa caatatagtc ttcccttcat
    12721 tttttaaagc cgataatatt tttagcacat caacatttgt ttgaaaatct agggcattga
    12781 atggctcatc taacaaaata atatcctgat tttccataat cgcttgagca attcctagtt
    12841 tttgtttcat tcctgaagaa taagttttta ctcgtgacct attatcagga tctagtccaa
    12901 cacgtttcat atattcttta attgtgctgt catcaatctt tccttgaata tctgctaata
    12961 actttagatt tgtaaatcca tcataaaagt caatgtatcc aggttgattt acaaatagcc
    13021 ccacatttcg ggggaaatcc aagtcttttc ctactttctt atctctaaca tagatctctc
    13081 catcatcaac aaactctaaa ccggtaatca ttttaaataa aacactttta cctgtcccgt
    13141 taccgcctac aattccaata gttttcccag cttcaatttc taaactggca ttttcataaa
    13201 gaacattttg tttgaatttt ttgtttatat ttttaatctt gataattccc atgtcttatc
    13261 ctcctcatat taataatagc aaagaaaata acattcaaaa cacatatggt agcaactttt
    13321 attacaagtt catttttatt gttaattcca tcaaataaat tagatagtcc aaaatttaaa
    13381 tcaaatagat taaaagttgg tagcatgaag aaaaaaaact taaaaaatag gattgctaaa
    13441 aaagatacta ttccattagc aaatttacat aaaattttaa aaatcacaaa atcaaaagtt
    13501 aaatttacaa ggaaaattac aaaatacata ctcaaaattc cgtatgtaaa ttttatattg
    13561 aattcactta taaaatattc attgctaaga gtacctgctc cacccataaa atagaacaca
    13621 ctacctaatg catacacaaa aagtgtatat agaaagatat aattcatata tactcctata
    13681 agtttgtgtt caaagctcaa cttgcttttt gttcgaatca atattggtgc ctgtccatat
    13741 ttttttattc tactatcagc tattcctata aaaaatagtg gtatcaaata caaaatagta
    13801 attcttaacc aaggaataaa tgacacgtat ttttcattag ttccaaacaa tgtcataata
    13861 ataacatcct tgaaattaaa atccacattt cctatttttc taagtagctc taacaaaaac
    13921 aatactaata ctactaaagc tgatatatat ttttcctttt ttgaaataat gaattcttta
    13981 aaaccatatt tgttaacttt gaacattctt ccaaaacaaa attggattac caatactcca
    14041 aatagaatag ttagtagaaa ctttgcggat ccatttacga ataatccatg gtgcagcaag
    14101 ataaaattgt caaagcaaac tatcggaata attgctttta attctgtctt aaaaccaata
    14161 aatgtcaata tataaataag taccgatgac aatattacat ttctatattt atatctataa
    14221 ttaatatacg aaagtaatga tatcaatact gtaaatccaa atagaaaata caccacattc
    14281 gaaattacag caaacaacga attactaaaa tattcaatat aagtatttaa aatgttaatt
    14341 aattcgtcat atgtttctac ctttatattt tgagtatgga ttgacaagtc aaacgttctt
    14401 attccaatca caaacgtaat aactaaatgt aataccatat atgccatcag ccattgaata
    14461 aaagactttg tagacatttt tatttgctgg aaagcatttc tatatcttat catctcaata
    14521 tcattaacgt ttctaatatg ccttgcaatt atgattagta aaattggaaa tacacagtat
    14581 aaaatataat aatgatttgt cagaatcgag agcatataac cccatattcc catatccact
    14641 tttctatatt ttcttattat gctgccgcat aagaagcata aaacaccaaa atttataagt
    14701 agtaacgtcc tgttttcaac aaaaatcctc ttacactttc tccccattaa atctactcct
    14761 taaaacagtt ccaataattg caattataag tataaaacat atacttccta tcgtaatatt
    14821 ggtaattgtc atagacctag gcttcaatct attcaaaaca aatgttgtag ttatactgaa
    14881 ccttgataag ccaagtatag atgtgatgaa attttctaca ataatatatg caaacggtgc
    14941 tatcaatgca agaaatagat tctcaatata cagcgccgtt atctgtccaa acaagcaaat
    15001 aattgttcca attaatgctt tttgtaatga ccacaaaatc ccaaaggcga ttgggttgta
    15061 catctgtaat tcaccaaaaa tatagtttgc taaggttggc ttgttgccag tttcaacaag
    15121 atctgcgata ttacatgaga aaaccactcc tattatattt actataaata ccattagaaa
    15181 acatactgcc atcgttgaca agatgtgaat aagtatatat tttttcctgg aaatacggac
    15241 gtgaacatat tctaaaaaat tatccttttt cataaaaaac gtataaatag aaaatggtat
    15301 acttacaatc aatccaaaaa agaaatcgat tggttctgat gcatatgaat atggactaat
    15361 ttgataatat atcatactat ttgagttata tattactata agtgtcatta aaacgactgc
    15421 ataaattata cctactgcga aagcaggaat agcttgtttt ctcatcgagc ttaaatataa
    15481 tctcataatt acttcctttc tttcacttaa aataggagac tattatgcaa tagtctccta
    15541 taacatgctg cttgtgttat aagaaatgtt aaattcgata ttaattactc ctccaagatc
    15601 caccaacttg aacatcaaca gttgtattcc agtcatttga gaactgaact cttacttaat
    15661 ccccatattt gtgatcaata tgtccgtcca agtcgtaata agaattatca tctacatctc
    15721 ttgtccaaga acctgcggtt ccatcatctt cttgcattct tgcatcaaca acataatccg
    15781 aaccaacata atcagaactc aagtcaccat ttgcaccacc aatatatttt gtttgatacg
    15841 cagtataacc atttccgtta agtctaccta ctgttgtgtt atagccttca taagttgttc
    15901 cagcataaac catcattgag ccaaatataa atatagcaaa cactgctaat aaagtcttaa
    15961 tctttttcaa ttgaagccct ccttgcttta ttatctctca cgaattttat ttttacatca
    16021 tataattagt tagttgattg gatatcgtaa aactaaaatt cctcacaacc aactcaaaga
    16081 taactcaatc accgttctta tacctttgag gattcatata attgctcata cttaaacctc
    16141 cctttatttt aatacacatc tttaattatc aatgattttt gctaataatt accacaatta
    16201 caatttaaac ttttatagtc ccttaccatc taaatcaaaa acctgataca tgcaaatgcc
    16261 taaagtatcg gctatatcat ttgctgtatt taatgtatgt ggagtctttt ccgtctctat
    16321 tttattcatt cttatccttg atattcctat ttttccaata tatgttggaa taatctcaat
    16381 ggctttttta tattctttaa gtttaattat tttaggttgt catatactat tttatcataa
    16441 tcatctttat ttgtcaacga ttattttttg ttttacataa ttcttctctt ttacttttat
    16501 ttacttcttc ttcgtgttct cccaaactaa tccatatttt tctcggttag ggttgtttca
    16561 atcttgccaa atgcaatcct actttcatca tctgtatgaa ttttttagat gatttaggta
    16621 ttcaagcatt tcatctcttc taatttatta taaatttctc aattttattc cacctcacat
    16681 aactaaaatg gctataaata caacttttaa atttcttatc ttcataataa taatcatctc
    16741 ctcttttatt ttaaaaaatt aaatgggaaa attaaaaatt cagtatctat aaaatacgaa
    16801 ccatcatctt ccaatttgtg atattttgta tatgagtata aaatagcttt atatgaaatt
    16861 gatcctccgt ctttataatg atattttatt ggaaaacaca ttattgataa aacaataaat
    16921 aaaataaaaa gcttgattct aacttttctt cttttcacga ctcaccacat tttctttaaa
    16981 tatacacaat catctgtaat tttcataaaa tttgggtatt agataaattc ttttactgtt
    17041 gttatttctt tgagtgttaa gtcacagtta ccgactattg tatctgcatg gtctttatag
    17101 attgctttta atttagattg tgcttgcagt attatacttg ctgatatttc tcttgaacga
    17161 attgttgcaa tcaatttttc aaatttagga attaaaccta tattggcaaa ctcatcaagc
    17221 aaacatctaa catgaactgg aagtcttcca ccatacacat catcagcctt ataacataag
    17281 ggaaaagtat tccttactcc ctacaacacc tgaaaagtcg aaattgacgg agactttcaa
    17341 aactttcccc tttgttttct aataaagtca gaaaaagaaa atgccaaaaa atgggtgtaa
    17401 aaaagcagcc tgtcatagag attgaccata tcgccgcaga tagtaaacgg atattctcag
    17461 ctaaaatagt tatcttcggt actgaataga taaaactttt cttctgtgag gtattcaagg
    17521 gatatttctc tttggcattt cctgcaccat gtccacaaag cgttgtactc ggcgtttcgg
    17581 ataacggctt tacaaaaagc atggaatgtg tactcgatat gctccttgta ttcttatgtg
    17641 caagtcatag aaattcctcc tttcctcagc ctaattttaa ccgatattta tttcaaaata
    17701 ggtagcaaaa acttcaaaag tgccaaacct aaaaatactg ttattaacgc aatcgttggg
    17761 gaaattatct tatatggaaa attcatttta ttcaacaaat gaatatccaa ataaaacaca
    17821 accaaaaaca atataaatgt aactatatat aatggattgt ggagaataaa gaatttatat
    17881 acaacatatt caatacagaa aaaaacaaat actgaaatta agcataaaaa aagtaaatgt
    17941 ataatttttt tcatgtttcc tcctctatga ttttcaaaaa ttagggcaac aacatttttg
    18001 ctgttgccct aattttttac tttatgattt taaagtttag tagctataaa gataaccaaa
    18061 atcattttta taccaatcgc cataggttcc cgggaatggg ttggagatag atctgccctt
    18121 agaaacagta gtatagaatt tatttaccat atttccagac cacataaact gtactttcat
    18181 gtattggttt ttgctcatac ccttaaaaca atcatacata ttagaacggt ctatactttt
    18241 taaccaattc caccctaaac caacagcagc cccaactgca accgaagcaa ctgtcgcagg
    18301 cgcaccagta attcccaaaa cagaacaaat ataagcacct aaagcagaan nnnnnnnnnn
    18361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn ngaacaaata
    18541 taagcaccta aagcagaacc agcagctcca gtaccaacaa gttccactaa atctttaaac
    18601 gcatcataac ttgcgctaga agccaaaata gccgctgcgg tatcccatgt tataaaatcg
    18661 acttctagtg tatacgttcc tgaaagaatt tctcctaaag ttaatggaga atgtccgcta
    18721 gtagtatcac gcacccacgc aacacctatg tcgccagaat aacttacgct accagtggtt
    18781 gaacgtgttt tcacaggata tgaaggttca gtgtctgctg ttttcttaat ttcgtccatg
    18841 ataagctgaa atttcaatcc aaaagataat ccgtctaatc ctaaacgaat ttcatcttct
    18901 gtgtaattat cagcaggaac ggcaaacgct tcttcaaaaa gtgtttccgc ttgctctaaa
    18961 ggaagattag ctaattcttc ctcattaagc tgaacaagtt cttcgacata atgtccctca
    19021 atagtatagg ggtcacgttc ctcagcagca aaggctgtga ttgtagttcc catacacaaa
    19081 acaatcgcca acaataaaga taaacatttc ttaaaacatt tcgtcataaa tactcactcc
    19141 tttttgacat acaatactgc aacaacaatt tccacgcttt tgatacccat tggaatcagg
    19201 aattacttcc tttcttacac tatttatggt actaaagagc acttgaaatc ttccagatgc
    19261 tttataaatt agtagaatat gagactcaaa ttaaaatcaa agtgcgacaa tccaaagtaa
    19321 atcattgttc taatacaatc ctatttattt tttctttcaa attataagag gttttatata
    19381 tcccctctat atctttattt tttgatttta cattgtacca gtatctattc tgcactaatt
    19441 ggattatctt ctactatctc aatctcatat tcttcatcat tctttatttt aattagatat
    19501 gctccatcag aataagcgat atccaaccct aaatattgat tatttgaatc atataaatta
    19561 caatccttat ttagtttatt caattcttct aaaactttcc tttgttgatc tgaagatata
    19621 tctagttctt taaaaccctc ttgtttctca tcataaatat atactttcac agactctcca
    19681 ttattttctt tatcaataat tatatcattt gaactagaac atgagcttaa attaaccata
    19741 agaattatta ttaacaataa ccctgctgtt ctttttacaa tagacttatt ataatcagtt
    19801 agaaaggtat ttgacatcca aaacataatt aatcaaatcc atcataactt ctattgcctc
    19861 taaatcctat agggcaatac tcagttatct tattaattct agttttttta tttatcaagt
    19921 ttatgaataa agattggtca atctccgttc ttataccttt gaggattcgt ataaatcacg
    19981 ataattacct ccctcttata attttgctta acctcaatat atttgacatt aaaatcaaat
    20041 attatctatt ttccaactgt tgtttctagc tatattatat aatatagcat ctaaactaat
    20101 cgccattact atatctcata ggatttaagt ccattatttc acctcctatc tatcttacat
    20161 atgagtttat ctttatcttt cctgataatg ttgtatttgt ttgattaata attgtaacta
    20221 tatatttact acctctatag gcttttactt ttaatgttga gtctgaagca aatctttcat
    20281 catagatgat ttttccatct tcttcaataa ttaccgaata gctaattcct cctgagcatg
    20341 acatatcttt taatctaact gtaaaaccat catgaaccgg accaaaccaa gtgtccatgt
    20401 tgaatttata actagtatta tcgaatctac cgaggcttat ctcctcgtct atatttgctg
    20461 atctaagtcc tatacttgat acttctccta actctaactt ttgatactct tcgtcactta
    20521 ttatttgaac cctatctcca aattccgagt taatattagt gactatttca cctttataaa
    20581 cctcctgtca ataagactta ttttcttatg tatttatctt aaagcattta gaacttattt
    20641 acatgagtaa atactgcaaa tttacaaaaa aataaaggca gtccgaagac tgccggtatt
    20701 tacctctctg cacctttgct atggtctttc ttgtttgatt tagttttatc gtctgtctta
    20761 aagcttttta tttgccctaa tattgacttt ttatccttgt cttgactctt tacttgttct
    20821 tttgctttta agagcttaga agacaaaata cgaacattct tatgttcctt tccgttgttg
    20881 tcaatgcttg tttttacttg tccaaatatt ttaacaaaat ctccttgctt taagttctct
    20941 aaatcttttg tcttatctcc ataggctgaa caattggtat aaattttgtt tccatcgtca
    21001 tcttttgaaa caattgaaaa attacttact ttaaattttt ctccatgtga attttctctt
    21061 tcaagatttt ctactttgcc agctatatta ccaacaagat ttataagatc atctttttct
    21121 tcaatatcac tgacattttc aacaatctta ccttgttctt tcatatcatc aatcatatag
    21181 tcaaaatcat cacttagtag acctgttatg tcattgttca tatataaaac atagacttct
    21241 tcaagtgcct tttcatcatt aacacctttt tctatactca caagtgcttt tataaagtcc
    21301 ttgtaattat cattcatcat ttcttctaaa ttttctctaa tatctttgta ttccataatt
    21361 tc
//
