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Overview
1.1
2.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_HE978593.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | ranthipeptide | 324,927 | 345,290 |

NZ_HE978594.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 2.1 | RRE-containing | 213,534 | 234,895 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | ranthipeptide | 324,927 | 345,290 |
Region 2.1 | RRE-containing | 213,534 | 234,895 |

No secondary metabolite regions were found in these records:
  NZ_HE978595.1
  NZ_HE978596.1
  NZ_HE978597.1
  NZ_HE978598.1
  NZ_HE978599.1

Compact view
NZ_HE978593.1 - Region 1 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 324,927 - 345,290 nt. (total: 20,364 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001887.1 |  | 0.16 | RiPP | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0000599.1 |  | 0.15 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0001607.1 |  | 0.14 | Other | gilvusmycin | Streptomyces sp. NRRL B-1347
BGC0000608.1 |  | 0.12 | RiPP | nocathiacin | Actinokineospora fastidiosa
BGC0000684.1 |  | 0.11 | Terpene | asperthecin | Aspergillus nidulans FGSC A4
BGC0000695.1 |  | 0.10 | Saccharide | fortimicin | Micromonospora olivasterospora
BGC0001707.1 |  | 0.09 | RiPP | nosiheptide | Streptomyces sp.
BGC0001591.1 |  | 0.09 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.09 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000807.1 |  | 0.09 | Saccharide | phosphonoglycans | Stackebrandtia nassauensis DSM 44728

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001887.1 |  | 0.47 | RiPP | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0000599.1 |  | 0.46 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0001607.1 |  | 0.43 | Other | gilvusmycin | Streptomyces sp. NRRL B-1347
BGC0000608.1 |  | 0.39 | RiPP | nocathiacin | Actinokineospora fastidiosa
BGC0000684.1 |  | 0.37 | Terpene | asperthecin | Aspergillus nidulans FGSC A4
BGC0000695.1 |  | 0.34 | Saccharide | fortimicin | Micromonospora olivasterospora
BGC0001707.1 |  | 0.34 | RiPP | nosiheptide | Streptomyces sp.
BGC0001591.1 |  | 0.34 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.34 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000807.1 |  | 0.32 | Saccharide | phosphonoglycans | Stackebrandtia nassauensis DSM 44728

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_HE978594.1 - Region 1 - RRE-containing
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 213,534 - 234,895 nt. (total: 21,362 nt) Show pHMM detection rules used
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RRE-containing | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000489.1 |  | 0.16 | RiPP | enterocin AS-48 | Enterococcus faecalis
BGC0000616.1 |  | 0.16 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000620.1 |  | 0.16 | RiPP | lacticin Q | Lactococcus lactis
BGC0000522.1 |  | 0.15 | RiPP | lacticin Z | Lactococcus lactis
BGC0000563.1 |  | 0.15 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000548.1 |  | 0.15 | RiPP | salivaricin A | Streptococcus salivarius
BGC0000775.1 |  | 0.14 | Saccharide | lipopolysaccharide | Legionella pneumophila
BGC0001887.1 |  | 0.14 | RiPP | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0000783.1 |  | 0.14 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0000774.1 |  | 0.13 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000489.1 |  | 0.46 | RiPP | enterocin AS-48 | Enterococcus faecalis
BGC0000616.1 |  | 0.46 | RiPP | amylocyclicin | Bacillus velezensis FZB42
BGC0000620.1 |  | 0.46 | RiPP | lacticin Q | Lactococcus lactis
BGC0000522.1 |  | 0.46 | RiPP | lacticin Z | Lactococcus lactis
BGC0000563.1 |  | 0.46 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0000548.1 |  | 0.45 | RiPP | salivaricin A | Streptococcus salivarius
BGC0000775.1 |  | 0.43 | Saccharide | lipopolysaccharide | Legionella pneumophila
BGC0001887.1 |  | 0.43 | RiPP | huazacin | Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0000783.1 |  | 0.43 | Saccharide | O-antigen | Xanthomonas oryzae pv. oryzae
BGC0000774.1 |  | 0.42 | Saccharide | lipopolysaccharide | Xanthomonas campestris pv. campestris

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names