LOCUS       NZ_KI912490.1          20261 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KI912490.1 Ruminococcus flavefaciens ATCC 19208
            L870DRAFT_scaffold00002.2, whole genome shotgun sequence.
ACCESSION   NZ_KI912490
VERSION     NZ_KI912490.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:56:51
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 440232
            Orig. end    :: 460493
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20261
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[450232:450493](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10261
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..20261
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20261
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="2"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             762..7472
                     /locus_tag="ctg2_347"
                     /transl_table=11
                     /translation="MRNSKKKNNTFKRVAAGALSMALVAGALPANVGGFLTGGKGIVAH
                     AETAYTAAETHVGLKLNVGDSFVIPESTHVKGYENMILWDGSTYDIGTQARTITVVRGE
                     NGALKLDGVEQNFTYPELESSTDQLCIIEYDNNSGWHLCGLVRCNAFTGVTSFDEINLY
                     GDTIDGCDVTKVENHMSRNCNVTISNIESGKKVRLTYSDNTTNDIEPTEGTVTFTSALT
                     THYADESNKKVNSVEIVPIPTDLTLTAPNLTYTSSAQNLIADAPQGTKFSLTAPVYSFN
                     HDAAWAEQLMLEEYYNSMEEAADSATDTSTQTNLINAARTLDRYRQAINHLYAGNPEDA
                     NSSIAAANASISEVNTDFSTENNDINAILDYINTYIRGKNLDDLKERFNTAADTSSWST
                     DVPQKTDAGTYTVYYQGDGVNYNKEIKKVDVIIAKANLSVGTDYTAPTGSDDLKYTAAD
                     IPLLEDGNTGSVTTVDSNTGEPVGTMEYGIAGTKEANIIKNTESEELTVGTVSVGDIYS
                     PVGNKGINIPKSAYSKYILDDKEYTSLASWTYLKYNGSRYYMTAQYEDPGLKDGCDAVR
                     VKEIRSDAIVFESYNSALETIDWKTTVPTAKDVGEYKVYYRVKGDANHNDTAPAFVTSA
                     IEYATASLTLSPSLTGAVIVENGATEALEATDGVYTLAGTKKYNIYTNKSIADSTAATA
                     LDLTSKSSNKTFGGNTYSYRYEIEVPTTPAEGGYILSHTNNYVGKVSTEVGKANVMNIQ
                     EDGVTTENVAVLNADGVIYYGDQLEKDELVTIADGYGSIVNVDEIYLENNTASGGKVTG
                     DALVIGTTYLLTAKVSVDADGDPDNGISGNTIYLKQQVTYAARPMTMNEYALKTEDGLV
                     PLEVSDGTVNVPAEYWVCTLKDDSSKTYIRVEEPDEALSALFTWEKKSTFVYNSAAQKP
                     VIVVKNGGDNTIVLADTAVAANETATPPVAAVAKDYNNAVAEKTDAGSYNYNLTAEANG
                     NYAGSVTVSWSIAQADVSDYITVAPKNNVDTDGNKETLEAVVYDGAVLDGTDFEVKTNE
                     AYAALAADSPVKKLVDEFIDQLKAKEAVAADPANNIEAQPAVPVKTFVNVSSGRYGVTT
                     DITYDSEISSSGVSINANSVGSYSNVILKGNLTFECSGGDFTEVKITCGEYVKSGSNSI
                     QLTLDGNDIKCGDDTILTKNDNEWFKIVSITHGYGNETNEYTINLTKVPKTETRYETYD
                     IKNAGAHKANVTVSNSNFKTVEFKQKIDNSGKPVEDEDNSVAVTIAKRDVTLTPDEDLS
                     MTYRDTEMPDLTYTIEDAKADGLTGVVAADKALFQKTTGEGSDAVTTNTGAIYVDKLVQ
                     EDAQAVPVQFVYATDENNDIDYTTAGLNNAGSYTYAVSEDDKFANYNIVLPIDIAADEA
                     QGIEEYTAPTFTVDPLNLKNIENLNIVLNGKTNGWTTDGNSGSYIYDGSTKQVEVSEVF
                     KPNEDVTETIDTIVNNDQKTAKQFTTEDESQISFDITYPIDENSHYIFVGKYDETYKGY
                     SLKITPPTGKAVKTIKFYTPNNEQPGTIYVNGEANAMVDFKTVYEAAGGNLETTGLKIS
                     KLEITYSSTDYTLNADTDYTVGGATKRASAGTHNVQIMGKGNYTGVTTAPWDITEAEAG
                     ESTLLIDNTPSNEYNGKSYDGKAVTANVSFGDGASAYYVADAETDIKYYENNNVLESAP
                     VDAGTYKVVATITCDGYATKTIEKTFNISPAVITVDSNAKTKAITYGDKLPAVTQADID
                     AIVGLTDDDKAYFQKLFTDGKLGLGYVKKYNANAQLVDDTSKLTFTLNGTLTQEEVGII
                     QQFSNNYNTSNFYWNVITNAKSIKDSSIKVEFTEGDTAIINPDGTFASDSAIKVYDTAI
                     LDQDGKATELVELGENNAATADYELTVESTATEGVYTLEIVGKNNYRGVRKIEFKAITA
                     AKAATTFDIDFVETYVSNNKNRIRFNAAASVKSGXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXX"
     CDS             7711..7806
                     /locus_tag="ctg2_348"
                     /transl_table=11
                     /translation="MSKYVEAELEIIAFDAEDVITTSCTGDSEPE"
     CDS             7907..9271
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_349"
                     /sec_met_domain="PF04055 (E-value: 9.3e-14, bitscore: 47.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5.4e-10, bitscore: 34.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIILKKGDERVAKIINKKNINTNAAYRISLFTYPYSENGRYLIKN
                     TLTHEVAELTEAEWTAFQQLKNAPADYDYIADNGLQQLVLSRYIVEMEHDDIKQYKNVV
                     YILKTMAKTNHGYSSYIIWPTTSCNARCIYCFEEGFKSRTMTTQTADRVIEFIKETKQG
                     GKIKIKWFGGEPLLGHKMISYMCRKLKESDIEFESTMITNCSLVTEKLAKEISELWNMK
                     RIQVSLDGDKADYEKRKCYCDTKKYNYDTAISGIRFLASEGIKVNLRCNVDNNNIDGLA
                     KFADQMKADLGDIQNIDMYLSPLYGVDECRPSEELFKKMAVLTDYFASIGVIKGGFFNK
                     DSKFKVNYCMADSMDKTIGIGPDGELNNCDSLLEQNVWGNIFDGVTNQTKFNELYSSAE
                     IDERCKKCCFLPQCTPFYRQRCPLYISECYEYKCMRTEYSLHTLLKGEPETEDDN"
     PFAM_domain     8276..8710
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_349_0021"
                     /evalue="3.00E-12"
                     /label="ctg2_349"
                     /locus_tag="ctg2_349"
                     /protein_end="268"
                     /protein_start="123"
                     /score="47.3"
                     /tool="antismash"
                     /translation="PTTSCNARCIYCFEEGFKSRTMTTQTADRVIEFIKETKQGGKIKI
                     KWFGGEPLLGHKMISYMCRKLKESDIEFESTMITNCSLVTEKLAKEISELWNMKRIQVS
                     LDGDKADYEKRKCYCDTKKYNYDTAISGIRFLASEGIKVNL"
     CDS             9261..9995
                     /locus_tag="ctg2_350"
                     /transl_table=11
                     /translation="MTTKKYRMANTVIEVTSIYDKVHEYCKEYETDEQADFFVSITSDD
                     IVFEREKTAREYAYEGKSAPDHSEGVLEETAVYRKIAEQMPKYDTFVFHGSVIAVDGHG
                     FLFTAKSGTGKSTHTALWREYLGDKAIMVNDDKPMLKVTDSGVIAYGTPYNGKHRLGCK
                     MSVPLKAICILTRGEKNSIVRIKKSEAYAMLLQQVYRPQDPLQMAKTLKLVDKLAASVE
                     LYKLACNMDIEAAEVAYNAMKG"
     CDS             10001..10261
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_351"
                     /sec_met_domain="PF05402 (E-value: 2.5e-13, bitscore: 45.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 8.5e-10,
                     bitscore: 33.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLSKAFLTHDDGDQKLLVSTGASKFSGLVRSNETAGFIISCLEK
                     DTTEAEIVAKMQNKYDGPKEAMERDVKKIIAQLRKIGAIDG"
     PFAM_domain     10052..10252
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_351_0022"
                     /evalue="1.40E-11"
                     /label="ctg2_351"
                     /locus_tag="ctg2_351"
                     /protein_end="84"
                     /protein_start="17"
                     /score="44.6"
                     /tool="antismash"
                     /translation="LVSTGASKFSGLVRSNETAGFIISCLEKDTTEAEIVAKMQNKYDG
                     PKEAMERDVKKIIAQLRKIGAI"
     CDS             10254..10688
                     /locus_tag="ctg2_352"
                     /transl_table=11
                     /translation="MANSTFEEQLAKNGKLIYTNKGDSMMPLIKQDRDLLIIKPVQGRL
                     KKYDVPLYKRDSGQYVLHRILKVRKNDYVICGDNRWVKEYGIRDRHIIGVLVAVIRNGK
                     EVSVNNWKYKVYVHLWCDLFPLRALMVHVISKISRYRKGK"
     CDS             10702..11361
                     /locus_tag="ctg2_353"
                     /transl_table=11
                     /translation="MKSLIRKIKGKYISTSKRVTYFFDGRKDKKICGCSLVKYVPSLYR
                     ESMGATGSQSTCYWALDKIFEGEVFSEDDAFIDVGCGKGRILAYMVSKSYPCSLTGIEL
                     NEEVAAYAKKWAEKYPQINIINGNAFDIDYNNYTVLFLGRPFETEMFHSFIDQLEEKLT
                     HKIKLFYWCDTQSGAYLENRKGWVRKRREMICKSHGLYMYFIPQGFSLWEYAVNEE"
     PFAM_domain     10930..11106
                     /aSDomain="Methyltransf_11"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08241.14"
                     /description="Methyltransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_353_0023"
                     /evalue="1.10E-05"
                     /label="ctg2_353"
                     /locus_tag="ctg2_353"
                     /protein_end="135"
                     /protein_start="76"
                     /score="26.0"
                     /tool="antismash"
                     /translation="IDVGCGKGRILAYMVSKSYPCSLTGIELNEEVAAYAKKWAEKYPQ
                     INIINGNAFDIDYN"
     CDS             11351..13072
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 257.5; E-value:
                     4.3e-78)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_354"
                     /transl_table=11
                     /translation="MKNSAVKWLYLVTEKKKWNIFLLMIVQALHGGSGVLYALLLRNIV
                     DNAVDGDRSGFRLNVLYIILLVLAQIAMRAVIRWLEEFSRSSLENLFKQRLFNNILTKD
                     FGTVSSVHSGEWLNRLTNDTVVIAQNSVEILPGLAGMIVKMVSAIVMMIVLDCRFALVL
                     LPLGIVIIFATYGFRNVLKKLHNNIQERDGKLRVYLQERLGSMMMIRSFAAEEQTEAEA
                     FDRMSDHKSSRMKRVRFSNLCNIGFNTGMQGMYVGGIIYCGYGILTGAISYGTLTAITQ
                     LISQIQSPFANITGYLPKFYAMTASAERLMEIEDFENDSDVKPMDIDETLDYYRSRFKA
                     MGLDNAEFAYYPSGDSVRQLSKDTMPVVLKDISVEIGKGQYVAFTGHSGCGKSTVLKLL
                     MCIYKLDGGRRYIIDKSGNTEKLSAKFHRLFAYVPQGNQLMSGTIRDVVCFADKSGLHD
                     DKRINEALKIACAYEFVNELDDGVDTLLGERGTGLSEGQMQRIAIARAIYSKCPILLLD
                     EATSALDEATERKVLENLKNMTDKTVVIVTHRPAALDICDRILQFTDNGVIENGKA"
     PFAM_domain     11408..12220
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_354_0024"
                     /evalue="1.10E-28"
                     /label="ctg2_354"
                     /locus_tag="ctg2_354"
                     /protein_end="290"
                     /protein_start="19"
                     /score="100.8"
                     /tool="antismash"
                     /translation="IFLLMIVQALHGGSGVLYALLLRNIVDNAVDGDRSGFRLNVLYII
                     LLVLAQIAMRAVIRWLEEFSRSSLENLFKQRLFNNILTKDFGTVSSVHSGEWLNRLTND
                     TVVIAQNSVEILPGLAGMIVKMVSAIVMMIVLDCRFALVLLPLGIVIIFATYGFRNVLK
                     KLHNNIQERDGKLRVYLQERLGSMMMIRSFAAEEQTEAEAFDRMSDHKSSRMKRVRFSN
                     LCNIGFNTGMQGMYVGGIIYCGYGILTGAISYGTLTAITQLISQIQSPF"
     PFAM_domain     12455..12913
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_354_0025"
                     /evalue="2.20E-23"
                     /label="ctg2_354"
                     /locus_tag="ctg2_354"
                     /protein_end="521"
                     /protein_start="368"
                     /score="83.4"
                     /tool="antismash"
                     /translation="LKDISVEIGKGQYVAFTGHSGCGKSTVLKLLMCIYKLDGGRRYII
                     DKSGNTEKLSAKFHRLFAYVPQGNQLMSGTIRDVVCFADKSGLHDDKRINEALKIACAY
                     EFVNELDDGVDTLLGERGTGLSEGQMQRIAIARAIYSKCPILLLDEATS"
     CDS             13059..14168
                     /locus_tag="ctg2_355"
                     /transl_table=11
                     /translation="MEKREFRKNAADMIYLTACAINNKKPRQERIDNLDLPKLFEVCQN
                     HILTACVAYALESVGIKDNEFTQAKEKAIRKNILLDVERGNILRRLEAEKIWYMPLKGA
                     ILKDWYPKLGMRQMSDNDILFDINHRNDVRNIMKEFGFELKAEREVVDEYLKKPIYNIE
                     MHGELFMEYQVGSMADYYRGIKERILKDDNNEFGYHFSNEEFYLFMLAHEYKHFTLDGT
                     GVRSLVDTYIFLRKFKCSLDWNYINTELDKLGIAEYEKQNRELAIKVCTLKQLTLEDKK
                     LLDYYVMSGTYGNKENTLKNSIKYRGKGSKLGYMLYRLFPPMSFLEVSVPWVKKSKLLI
                     PPAYIYRFYRCVTSSKKSVEREVKQLGKT"
     PFAM_domain     13158..13829
                     /aSDomain="NTP_transf_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14907.8"
                     /description="Uncharacterised nucleotidyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_355_0026"
                     /evalue="3.80E-33"
                     /label="ctg2_355"
                     /locus_tag="ctg2_355"
                     /protein_end="257"
                     /protein_start="33"
                     /score="115.2"
                     /tool="antismash"
                     /translation="LDLPKLFEVCQNHILTACVAYALESVGIKDNEFTQAKEKAIRKNI
                     LLDVERGNILRRLEAEKIWYMPLKGAILKDWYPKLGMRQMSDNDILFDINHRNDVRNIM
                     KEFGFELKAEREVVDEYLKKPIYNIEMHGELFMEYQVGSMADYYRGIKERILKDDNNEF
                     GYHFSNEEFYLFMLAHEYKHFTLDGTGVRSLVDTYIFLRKFKCSLDWNYINTELDKLGI
                     AE"
     CDS             complement(15036..15242)
                     /locus_tag="ctg2_356"
                     /transl_table=11
                     /translation="LLLQTEDFLESSEYFSWEHYYTKLLVSEAEDTYLQYSKLKLNDVY
                     LNPNEKTAIFKATDIISKIIENN"
     CDS             complement(15528..15998)
                     /locus_tag="ctg2_357"
                     /transl_table=11
                     /translation="MLKIVFGDTDNSIYHPPTYFDNTYEDEWITYPRSVKMIKDIDKSD
                     VAGARVIDSPVLGSISVKELSGGVKTLILMLFDESGKTTLVSLIDTYDRLGADSGIEIS
                     CAKRCLTINNSNWESVLNSVSDSIIFIDEENTIVKSDDFAKKYRRPIIIMLS"
     PFAM_domain     complement(15753..15962)
                     /aSDomain="DUF4869"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16163.7"
                     /description="Domain of unknown function (DUF4869)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_357_0027"
                     /evalue="2.60E-28"
                     /label="ctg2_357"
                     /locus_tag="ctg2_357"
                     /protein_end="82"
                     /protein_start="12"
                     /score="98.5"
                     /tool="antismash"
                     /translation="IYHPPTYFDNTYEDEWITYPRSVKMIKDIDKSDVAGARVIDSPVL
                     GSISVKELSGGVKTLILMLFDESGK"
     CDS             complement(16058..16255)
                     /locus_tag="ctg2_358"
                     /transl_table=11
                     /translation="MKATGIVRRIDDLGRVVIPKEIRRTMRIREGDPLLKSLTPDMEFC
                     KAMDEICKRVHTAKKNYSAS"
     aSDomain        complement(16151..16234)
                     /aSDomain="TIGR01439"
                     /aSTool="tigrfam"
                     /description="lp_hng_hel_AbrB: transcriptional regulator,
                     AbrB family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_358_0002"
                     /evalue="2.70E-10"
                     /identifier="TIGR01439"
                     /label="ctg2_358"
                     /locus_tag="ctg2_358"
                     /protein_end="35"
                     /protein_start="7"
                     /score="37.8"
                     /tool="antismash"
                     /translation="RRIDDLGRVVIPKEIRRTMRIREGDPLL"
     PFAM_domain     complement(16154..16231)
                     /aSDomain="MazE_antitoxin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04014.20"
                     /description="Antidote-toxin recognition MazE, bacterial
                     antitoxin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_358_0028"
                     /evalue="2.70E-06"
                     /label="ctg2_358"
                     /locus_tag="ctg2_358"
                     /protein_end="34"
                     /protein_start="8"
                     /score="27.2"
                     /tool="antismash"
                     /translation="RIDDLGRVVIPKEIRRTMRIREGDPL"
     CDS             17000..18286
                     /NRPS_PKS="Domain: Beta_elim_lyase (43-288). E-value:
                     5.4e-08. Score: 24.2. Matches aSDomain:
                     nrpspksdomains_ctg2_359_Beta_elim_lyase.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     238.9; E-value: 1.6e-72)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_359"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.2e-74,
                     bitscore: 245.8, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFVKKNIIKPFENKIWLSSPTMHGDEQKWVNDAFEKNWITTAGEN
                     VNEVERLVAEYTGVKYAVALSCGTASLHLATKLAGEKLYGQPKPNCGTLQGHKVFCSDM
                     TFDATVNPVAYEDGEAVFIDTEPQTWNMCPKALEKAFEIYPDVKLVVVAHLYGIPGKID
                     EIRKICDKHGALIVEDAAESFGAKYKGRETGSFGDYCAISFNGNKIITGSSGGMFLTNS
                     KDDADKIRKWSTQSREDAPWYQHEEIGYNYRMSNIIAGVVRGQIKYIDEHIAQKKAIYE
                     RYREGFKGLPVTMNPFDEKNSEPNYWLSCLLINKEAMCRQVRSENEPMYIPEHGKSCPT
                     EILDTLLKYNAEGRPIWKPMHMQPIYRMNGFVTANGNGRGQSNAYIDRGEAVDIGADIF
                     ERGLCLPSDNKMTAEQQDIIIELIRSCFE"
     PFAM_domain     17066..18268
                     /aSDomain="DegT_DnrJ_EryC1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01041.19"
                     /description="DegT/DnrJ/EryC1/StrS aminotransferase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_359_0029"
                     /evalue="6.60E-72"
                     /label="ctg2_359"
                     /locus_tag="ctg2_359"
                     /protein_end="423"
                     /protein_start="22"
                     /score="242.8"
                     /tool="antismash"
                     /translation="HGDEQKWVNDAFEKNWITTAGENVNEVERLVAEYTGVKYAVALSC
                     GTASLHLATKLAGEKLYGQPKPNCGTLQGHKVFCSDMTFDATVNPVAYEDGEAVFIDTE
                     PQTWNMCPKALEKAFEIYPDVKLVVVAHLYGIPGKIDEIRKICDKHGALIVEDAAESFG
                     AKYKGRETGSFGDYCAISFNGNKIITGSSGGMFLTNSKDDADKIRKWSTQSREDAPWYQ
                     HEEIGYNYRMSNIIAGVVRGQIKYIDEHIAQKKAIYERYREGFKGLPVTMNPFDEKNSE
                     PNYWLSCLLINKEAMCRQVRSENEPMYIPEHGKSCPTEILDTLLKYNAEGRPIWKPMHM
                     QPIYRMNGFVTANGNGRGQSNAYIDRGEAVDIGADIFERGLCLPSDNKMTAEQQDIIIE
                     LI"
     aSDomain        17129..17863
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg2_359_Beta_elim_lyase.1"
                     /evalue="5.40E-08"
                     /label="ctg2_359_Beta_elim_lyase.1"
                     /locus_tag="ctg2_359"
                     /protein_end="288"
                     /protein_start="43"
                     /score="24.2"
                     /tool="antismash"
                     /translation="ENVNEVERLVAEYTGVKYAVALSCGTASLHLATKLAGEKLYGQPK
                     PNCGTLQGHKVFCSDMTFDATVNPVAYEDGEAVFIDTEPQTWNMCPKALEKAFEIYPDV
                     KLVVVAHLYGIPGKIDEIRKICDKHGALIVEDAAESFGAKYKGRETGSFGDYCAISFNG
                     NKIITGSSGGMFLTNSKDDADKIRKWSTQSREDAPWYQHEEIGYNYRMSNIIAGVVRGQ
                     IKYIDEHIAQKKAIYERYREGFK"
     CDS             18286..18921
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 230.3; E-value:
                     7.8e-70)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_360"
                     /sec_met_domain="Bac_transf (E-value: 9.6e-60, bitscore:
                     196.1, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYAKYFKRMFDFILSLGAIIVLFPVLFLLTVVGAVAMGGNPFFTQ
                     ERPGKNEKIFKLVKFRTMNNKRDKHGKLLPDEKRLTSYGKWLRSTSLDEIPELFNILNG
                     DMSIIGPRPLLVKYLPYYSKAQHHRHDVRPGLTGYAQAHGRNASTWDERFEYDLKYVKH
                     ITFIGDVKIIIDTVKAVLKKEGISAEGQATMGDFIDYVNEKRATVSEV"
     PFAM_domain     18304..18828
                     /aSDomain="Bac_transf"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02397.18"
                     /description="Bacterial sugar transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_360_0030"
                     /evalue="1.20E-59"
                     /label="ctg2_360"
                     /locus_tag="ctg2_360"
                     /protein_end="181"
                     /protein_start="6"
                     /score="201.1"
                     /tool="antismash"
                     /translation="KRMFDFILSLGAIIVLFPVLFLLTVVGAVAMGGNPFFTQERPGKN
                     EKIFKLVKFRTMNNKRDKHGKLLPDEKRLTSYGKWLRSTSLDEIPELFNILNGDMSIIG
                     PRPLLVKYLPYYSKAQHHRHDVRPGLTGYAQAHGRNASTWDERFEYDLKYVKHITFIGD
                     VKIIIDTVKAVL"
     CDS             18925..20142
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_361"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.3e-35,
                     bitscore: 115.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LQTENSLISVIVPIYKIDKYIGICIESLINQTYDNLEIILVDDGS
                     PDRCPEICDLYAKKDKRIKVIHKENGGLVSARKAGLLVSNGEYIGYVDGDDWVGAGFYE
                     ALYTAIVTSNADIVCAGQSRDLFDRSVHFTNSLPSGIYEGTKLEDLYRNMISNGEFYRP
                     GVTTYVWNKLFKREVLMEAQLNVDDRISIGEDGAVTYPALLASRKVCITDNCAYHYRQR
                     EDSMLKKSESFANEAKKLRYLYDYLMDFAKKHDNKYDLIKQITDYVLSICIIRSGGILD
                     ATVTETEFTPYGSKIDGKKIVIYSAGTFGQQLMNRFLENSRCDVVGWVDDDYWEYRRCC
                     MDVDPVESITKLDYDYVLVATVDRILAKNISNRLLDYGMSKDKILIVSCEESIREELLE
                     RYLNCK"
     PFAM_domain     18949..19296
                     /aSDomain="Glycos_transf_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00535.28"
                     /description="Glycosyl transferase family 2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_361_0031"
                     /evalue="2.90E-31"
                     /label="ctg2_361"
                     /locus_tag="ctg2_361"
                     /protein_end="124"
                     /protein_start="8"
                     /score="108.7"
                     /tool="antismash"
                     /translation="SVIVPIYKIDKYIGICIESLINQTYDNLEIILVDDGSPDRCPEIC
                     DLYAKKDKRIKVIHKENGGLVSARKAGLLVSNGEYIGYVDGDDWVGAGFYEALYTAIVT
                     SNADIVCAGQSR"
ORIGIN
        1 tccaacgcac ctgcctcctt ttcattagta ttattcccca ataatatagg tttagtcacc
       61 gtgaattatt actcgccgtt atagatgctc gcatacggca ggcgatacgt tacacctgtt
      121 atagctgttt tcagaagctt attcctgcta tggtgcttgc ttgataacgc tcccatacag
      181 gcgaattctc cctgttcaag ctgatttgat ctgtcaaagc taatgtgtgt ctcagacgat
      241 atggcaacag cataaacttc aattgttcca caaacgtccc tgcacagtaa aaacgcaatt
      301 tttccatact ttttgtatag tttgaagctc gatcatctac tcggaaaaag taaaattata
      361 ctaaacgaac agccttggtt tgtgagtatt gccaatttat attaactaat tatgaatttc
      421 aaagaatcgg acgtgacatt tatttttcag tgtggtataa tacgactatg ttcagaaaga
      481 aaaaatatga acataaagag acaagataca gaacgaagaa atcatgtttt aggggctgaa
      541 gttaaaatgc aaaaggtatg taactttaag aagtttatgt ctttatatat ttacaaatgc
      601 tataactctg cccgttcaca atttaatgat ctaaaagcgt gctgacaggc taattatgcc
      661 tataggtgcg ctttttatat tttgcagcgg caaagtctta ggggttgagc gacttgctgc
      721 tgcgggaaat ttacattctt aataaggagg aaatgagctt tatgagaaac tcaaagaaga
      781 aaaacaacac atttaaaaga gtggcagcag gtgcgctgtc tatggctctt gtagcgggtg
      841 cgttacctgc aaacgtagga ggctttttga caggaggcaa gggtattgtt gctcatgcgg
      901 aaacagcata tacagctgca gaaactcatg ttggattaaa gctcaatgtt ggcgacagct
      961 ttgtgattcc tgaatccact catgtaaaag gttacgaaaa tatgattctt tgggatggat
     1021 ctacttatga cattggtaca caggctcgca ccataactgt tgtccgtggt gagaacggtg
     1081 ctctcaagct tgatggggtt gagcagaatt ttacttatcc tgaactcgaa agtagcacag
     1141 atcagctttg cataattgaa tatgataaca actctggctg gcatttatgt ggacttgttc
     1201 gctgtaacgc ttttaccgga gtgacatcgt ttgatgaaat taatttatac ggcgatacta
     1261 tcgatggctg tgatgttaca aaggtagaaa atcatatgtc tcgtaattgt aatgttacca
     1321 tttcaaatat cgaatccgga aagaaagtgc gcctgactta ttcggataat acaactaatg
     1381 atattgaacc tactgaaggt acggtcacat ttacaagtgc attgactaca cattacgctg
     1441 atgaaagtaa taaaaaggtt aattcggtag agatagtgcc tattcctact gacctcaccc
     1501 tcactgcacc aaatcttaca tacaccagca gtgcgcagaa tcttattgca gacgctccac
     1561 agggcacaaa gttcagcctg acagcgccgg tatattcttt taaccatgac gctgcttggg
     1621 ctgaacagct catgcttgaa gaatattaca attccatgga agaagcagcg gattcagcta
     1681 ctgatacatc aacccaaacg aatcttatta atgctgcacg taccttagat cgttatcgtc
     1741 aggctattaa tcatttatat gcaggtaacc cagaagatgc taatagtagt atagcggcag
     1801 ctaatgcttc tataagcgaa gtgaatactg attttagcac agaaaataat gatatcaacg
     1861 caattctcga ttatattaac acatacatca ggggcaaaaa cttagatgac ctgaaagaac
     1921 gctttaatac tgctgctgac acttcctctt ggagcaccga cgttccccaa aaaaccgacg
     1981 caggcactta caccgtttac tatcagggtg acggcgtgaa ttacaacaaa gaaatcaaga
     2041 aagttgatgt tattatcgcc aaggctaatc tcagtgtagg cacagactac accgccccca
     2101 ccggcagcga cgacctgaaa tatacagctg ctgacattcc gcttcttgaa gacggcaata
     2161 ccggctcagt tactactgtt gacagcaata ccggtgagcc tgttggcaca atggagtatg
     2221 gtatagcagg cactaaagaa gcaaatatta ttaagaatac tgagtcagaa gagctaacag
     2281 tgggcacggt ttcggtaggt gatatttatt ctcctgttgg taataagggc ataaatatcc
     2341 ctaaatctgc ttactctaag tatatacttg acgataaaga gtatacgagt ttagcatctt
     2401 ggacatattt aaaatataat ggtagtagat actacatgac agctcaatat gaagaccccg
     2461 gtttgaaaga cggctgtgac gctgttcgtg tgaaagaaat ccgtagtgat gcaattgttt
     2521 ttgaatcgta caattcggca ttggaaacca tcgactggaa aaccactgtt cccacagcca
     2581 aagacgtagg cgaatacaaa gtttactaca gagtaaaggg cgacgctaac cacaacgaca
     2641 ctgctcctgc atttgtaact tctgctatcg aatacgctac agcctctctt acactcagtc
     2701 cgtctctgac aggcgcagtt atcgttgaaa acggcgctac tgaggctctt gaggcaacag
     2761 acggcgtata tacgctcgca ggtactaaga agtacaacat ctatacaaat aagtctatcg
     2821 ctgacagtac agcagctaca gctcttgacc tgacttccaa gagctccaat aagactttcg
     2881 gcggtaatac atatagctac cgttatgaga tagaggttcc cacaactcct gccgagggcg
     2941 gctatatcct ctctcacaca aataactacg tcggcaaggt aagcaccgaa gtgggcaagg
     3001 cgaatgtcat gaacattcag gaggacggcg ttactacaga gaacgttgct gttctcaatg
     3061 cagacggtgt tatctattac ggcgaccagc ttgaaaaaga tgagcttgtt actatcgcag
     3121 acggctacgg cagcattgtt aatgttgacg agatctatct tgaaaacaat accgcaagcg
     3181 gcggcaaggt aacaggtgac gctcttgtta tcggtacgac ctaccttctt acagcgaagg
     3241 tatctgttga cgcagacgga gatcctgata acggcataag cggcaacacc atatacctca
     3301 agcagcaggt cacttatgcg gctcgtccta tgactatgaa cgagtacgcc ctcaagaccg
     3361 aggacggctt agttccgctg gaagtatcag acggcacagt taatgttcct gcggaatact
     3421 gggtatgcac gctaaaagat gacagttcta aaacatatat cagggtggaa gaacctgatg
     3481 aagcattaag tgctttattc acttgggaaa agaagtccac attcgtttac aacagcgcag
     3541 ctcagaagcc cgttatcgtt gtaaagaacg gcggcgataa tactatcgtg cttgctgata
     3601 cagcagttgc agctaatgag acagcaactc ctcctgtagc agcagttgct aaggactata
     3661 acaacgctgt tgcagaaaag actgacgcag gcagctacaa ctataacctc acagcagagg
     3721 caaacggaaa ctacgcaggc agcgtgacag tttcatggtc tatcgcacag gctgacgtaa
     3781 gcgattacat tacagttgct cctaagaaca acgttgatac agacggcaat aaggaaactc
     3841 tcgaagctgt tgtttatgac ggtgcagttc ttgacggcac tgacttcgag gttaagacta
     3901 acgaagcata tgcagctctt gcagcagatt cacctgtaaa gaagctcgtt gacgagttca
     3961 tcgaccagtt aaaggctaag gaagctgtag cagctgaccc tgctaataac atcgaggcac
     4021 agcctgctgt tcctgttaag acttttgtca atgttagcag cggacggtat ggggttacta
     4081 cagatataac ttatgatagt gaaatatctt caagtggtgt aagtattaac gctaactctg
     4141 tgggatcata tagtaatgtt attttgaagg gaaatcttac tttcgaatgc agtggcggtg
     4201 attttactga ggtaaagatc acttgtggtg aatacgtaaa gtcaggaagt aatagtattc
     4261 agttaacttt ggatggtaac gacataaagt gcggcgatga cactatcctt acaaagaatg
     4321 ataacgagtg gttcaagata gtaagcataa cacatggata tggcaatgag acaaatgaat
     4381 acactattaa tttgacgaaa gtcccgaaaa cagaaaccag atacgaaaca tacgatatca
     4441 agaacgcagg tgcacacaag gctaacgtaa cagtatccaa cagcaacttc aagactgttg
     4501 aattcaagca gaagattgat aatagcggca agcctgttga ggacgaggat aattctgtag
     4561 ccgtaactat cgcaaagcgt gatgttactc tgacaccaga cgaagatctg tcaatgacat
     4621 accgcgacac agagatgccc gacctcacat acactatcga ggacgcaaag gctgacggtc
     4681 tcacaggtgt tgtggctgct gataaggctc tgttccagaa gacaacaggc gagggctcag
     4741 atgctgtcac aactaataca ggtgctatct atgtagataa gctcgttcag gaagatgcac
     4801 aggcagttcc tgttcagttc gtttacgcaa cagatgagaa taatgatatc gactacacaa
     4861 cagcaggtct caacaatgca ggcagctaca catacgcagt aagcgaggac gataagtttg
     4921 caaactacaa catcgttctt cctattgata ttgcggctga cgaggcacag ggaatcgagg
     4981 aatacacagc tcctacattc actgttgatc cactcaatct caagaatatc gaaaacctga
     5041 acatcgtgct caacggcaag accaatggct ggacaactga cggcaacagc ggttcttaca
     5101 tctatgacgg ctctactaag caggtagaag tttctgaggt attcaagcca aacgaagatg
     5161 tgactgaaac tattgataca atagtaaata atgatcagaa aacggctaag cagttcacaa
     5221 ccgaagacga atcacagata tccttcgata taacttatcc tatagatgaa aattctcatt
     5281 atatctttgt cggaaagtat gatgaaacat acaaaggata ttccttgaag ataacacctc
     5341 ccactggaaa agctgtaaag actattaagt tctatacacc taataatgaa cagcctggaa
     5401 cgatttacgt gaacggagag gcaaatgcta tggtcgactt caagacggtt tatgaagctg
     5461 ccggcggcaa tttggaaact acaggactga aaatttccaa gcttgaaatc acctattctt
     5521 ctactgacta cacccttaac gcagacactg actacaccgt aggcggcgca acaaagagag
     5581 cttccgcagg tacacacaat gtacagatca tgggtaaggg caactataca ggcgttacta
     5641 cagctccatg ggatatcact gaggctgagg ctggcgagtc aacactgctt attgataata
     5701 caccttccaa tgaatataat ggcaagtctt acgacggcaa ggctgtaact gctaatgttt
     5761 cattcggaga tggagcttct gcttattatg tagcagacgc agagacagat atcaagtatt
     5821 atgaaaataa taatgtcctt gagagcgcac ctgtggatgc aggcacctat aaggtagttg
     5881 ctactatcac ttgtgacggc tatgcaacca agactatcga aaagacattc aatatcagtc
     5941 ctgctgtcat cactgtagat tcaaatgcaa aaacaaaggc aataacatac ggcgataagc
     6001 tcccggcagt aacacaggct gatattgacg ctatcgtagg tcttaccgat gatgacaagg
     6061 catacttcca gaagctcttc acagacggca agctggggct tggctatgta aagaaatata
     6121 atgcgaatgc acaattggtt gacgatactt caaaactcac tttcacactt aacggaacat
     6181 taacacagga agaagtaggt ataattcagc agttcagcaa taattacaat acctctaact
     6241 tctactggaa tgtcataacc aatgctaagt ctatcaagga cagcagcata aaggtcgagt
     6301 tcacagaggg cgatacagct atcatcaatc cagacggcac tttcgcttct gacagtgcta
     6361 tcaaggttta cgataccgct atcctcgatc aggacggcaa ggctactgag cttgttgaac
     6421 tcggtgagaa caacgcagca acagctgatt atgagcttac agttgaaagc actgctacag
     6481 aaggtgttta tacacttgag atcgtcggca agaacaacta ccgcggtgtt cgcaagatcg
     6541 agtttaaagc tattacggca gctaaggcag caacaacatt tgacattgat ttcgttgaaa
     6601 cttatgtttc aaataacaag aacaggatca gatttaacgc agcagcttcc gtaaagagcg
     6661 gctannnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7441 nnnnnnnnnn nnnnnnnnnn nnnnnnnctt agtgattcct atctggtagg tctgcttgac
     7501 aacggcaacg gcgtatatgc aagattctat tctatcgtaa atgacggtac aaatgactat
     7561 gttgtatatg caactgatga ggctgtaatt tataattatg ccgaattgtc tgcatcattg
     7621 agctaacaat ttatttggta ataatcgagt gcaatttcac acgattcatt acatagatcg
     7681 atctattata tgaatggagg tgttttccta atgtcaaagt atgtagaggc tgagcttgag
     7741 atcatcgcat ttgatgctga ggacgttatt actacttctt gtactggcga ttctgaacca
     7801 gagtaatctt gattattcag gttttggttc attgaactaa tggtggaggc tgtgcggcta
     7861 taaacgctgt acagcctttt gccagtataa ctctaaaggt gatggaatga taatattaaa
     7921 aaaaggcgat gaaagagttg caaagatcat aaataaaaaa aacatcaaca ctaacgcagc
     7981 gtatcgtatc tcactgttta catatccata ttccgaaaac ggcagatatc ttataaagaa
     8041 tacgctgaca catgaagttg ccgagctgac cgaagctgaa tggacagctt ttcagcagtt
     8101 aaaaaatgca ccggcagact atgactatat tgccgataac ggactgcagc agcttgtatt
     8161 atcaagatat atcgttgaaa tggaacatga tgatatcaag cagtacaaga atgttgttta
     8221 tattcttaaa accatggcaa agacaaatca tggctacagt tcatatatca tctggccgac
     8281 aacgagctgc aatgcaaggt gcatttactg ttttgaggag ggctttaaaa gcagaactat
     8341 gaccactcaa acagctgaca gagtgataga attcataaaa gagactaagc agggcggcaa
     8401 aataaagata aaatggtttg gcggtgagcc gctgttaggt cacaaaatga tctcatatat
     8461 gtgtaggaaa ctaaaagaga gtgatattga atttgaatca acgatgataa caaattgtag
     8521 ccttgtcaca gagaaacttg caaaagagat aagcgaactc tggaatatga agaggataca
     8581 agtctcatta gacggcgaca aagctgatta tgaaaaaaga aaatgctatt gcgacactaa
     8641 aaagtataac tatgacacag cgataagcgg catacgtttc cttgcgtcag agggaataaa
     8701 ggtaaatctg aggtgtaatg tagacaacaa taatattgac ggacttgcaa agtttgcaga
     8761 tcaaatgaaa gccgatctgg gagatataca gaatattgat atgtatcttt cgccattgta
     8821 tggcgttgac gagtgcagac cttctgagga gctattcaaa aaaatggcag tccttactga
     8881 ctattttgct tcaatagggg tgataaaggg cggttttttc aataaagaca gcaaattcaa
     8941 ggtcaattac tgtatggctg attctatgga taagaccata ggaataggtc ccgacggaga
     9001 gcttaataac tgtgattcct tattagagca gaatgtctgg gggaatattt ttgacggcgt
     9061 aaccaatcag acgaagttta atgagcttta cagttcagcc gaaatagatg aaagatgcaa
     9121 aaaatgctgt tttcttcctc aatgtacgcc gttctatagg cagagatgtc cgctgtatat
     9181 aagcgaatgc tatgagtata aatgtatgcg tacagagtac tcgctgcaca cattgctgaa
     9241 aggagaacct gaaacagaag atgacaacta agaaatatag aatggcaaat acagtcattg
     9301 aggttacttc tatatatgat aaagtccatg aatactgtaa ggaatatgaa acagatgagc
     9361 aggctgactt ttttgtttct atcacttcag atgatatcgt ctttgagcgc gaaaagactg
     9421 ctcgtgaata tgcttatgag ggaaagtctg cacctgatca ttccgagggc gtactggagg
     9481 aaacggcagt ataccgcaag atcgcagaac aaatgccaaa atatgatact tttgtttttc
     9541 acggttcagt catagccgta gacggacatg gctttttatt tacagctaaa tcaggcacag
     9601 gtaaatcaac gcatactgct ctgtggcgag agtatctcgg cgacaaggcg ataatggtga
     9661 atgatgacaa gcctatgctg aaagtgacag acagcggagt tatagcctat ggtacgccgt
     9721 ataacggcaa gcacaggctt ggctgtaaga tgtcagtacc gttaaaagca atatgtatac
     9781 ttactcgcgg cgagaaaaac agtatcgttc gcataaaaaa atcagaagcc tatgcaatgc
     9841 ttttgcagca ggtataccgt ccgcaggatc ctctgcaaat ggctaaaact ctcaagcttg
     9901 tggacaagct ggcagcgagc gtcgagctct acaagctcgc ctgcaacatg gatattgaag
     9961 cggcagaagt cgcatataat gcaatgaaag gataattatt atgaaactca gtaaagcatt
    10021 tttaacacac gatgacggtg atcagaagct ccttgtttcc acaggagcaa gcaagttttc
    10081 gggacttgtc cgcagcaatg aaacagcagg atttattata tcctgtcttg aaaaggatac
    10141 tacagaagct gagatagttg caaaaatgca gaataagtac gatggtccaa aagaggctat
    10201 ggaacgcgat gtaaagaaaa taatcgctca gctcagaaaa atcggagcta tagatggcta
    10261 attcaacttt cgaggaacag cttgccaaaa acggcaagct catatacacg aataagggcg
    10321 acagtatgat gccgcttatc aagcaggaca gggatctgct tattatcaag cctgttcaag
    10381 gaagactaaa aaaatatgat gttccgcttt ataagcgcga cagcggacag tatgtgcttc
    10441 accgtatcct aaaagttcgc aaaaacgatt acgttatatg cggcgataac cgctgggtta
    10501 aggaatacgg tatccgtgac cggcatataa tcggcgtttt ggtagcggtt atccgaaatg
    10561 gtaaggaagt ttccgtcaat aactggaagt acaaggtgta tgttcactta tggtgcgact
    10621 tgtttcccct aagagcgctg atggttcatg taataagtaa aataagcaga tatagaaaag
    10681 gaaaatgaca tggagaaaaa aatgaaatca ctgatcagaa aaattaaggg taagtatata
    10741 agtacgtcca aaagagtaac atatttcttt gacggaagaa aggacaaaaa aatctgtggg
    10801 tgttcacttg tgaaatatgt tccttcttta tatcgtgagt caatgggagc aaccggcagt
    10861 caatcaacct gttattgggc tttggataag atctttgagg gcgaagtatt ctctgaagat
    10921 gacgctttta ttgatgttgg ctgcggaaaa ggtcgtatac ttgcatacat ggttagcaaa
    10981 tcatatccat gttctttgac aggtatagaa ttaaatgaag aagttgctgc ttacgcaaaa
    11041 aaatgggcgg aaaagtatcc gcaaattaat attataaacg gcaatgcttt tgacattgac
    11101 tataataact atactgtttt atttttaggc agaccatttg aaaccgaaat gtttcatagt
    11161 tttattgatc agcttgaaga gaaactgaca cacaagataa agttattcta ttggtgtgac
    11221 acacaaagcg gtgcatatct tgaaaataga aaaggctggg tgcgaaaacg ccgcgaaatg
    11281 atatgtaaga gtcacggatt gtatatgtat ttcattccgc agggattttc gttatgggaa
    11341 tacgctgtaa atgaagaata gtgcagtaaa gtggctatat ttggtcacag aaaagaaaaa
    11401 atggaatatc ttcctactga tgatagtgca ggcacttcac ggtggcagcg gagttcttta
    11461 tgcacttctg ctgagaaata tcgtcgataa tgctgttgac ggtgacagga gcggcttcag
    11521 gctgaacgtc ctatacatca ttctcctagt actggcgcaa attgcaatga gggctgtaat
    11581 tcgatggctt gaggagtttt cccgttcttc cctcgaaaac cttttcaagc agagactgtt
    11641 caacaatatt cttaccaaag atttcggaac tgtcagttca gtacattcag gcgagtggct
    11701 gaaccgcctt acgaatgaca cggtcgtgat cgcacagaac agtgttgaga tacttcccgg
    11761 acttgcggga atgatagtga aaatggtaag cgcaattgta atgatgatag ttcttgactg
    11821 ccgctttgca cttgttctgc tgccattggg aatagtcatc attttcgcca cgtatggctt
    11881 ccgaaatgtg ctgaaaaagc ttcataataa tatacaggag cgggacggaa agctccgtgt
    11941 atatttgcag gaacgcctcg gaagtatgat gatgatacgt tcatttgctg cggaagaaca
    12001 gaccgaagcc gaagcttttg atagaatgtc tgaccataag agttcgcgca tgaagcgcgt
    12061 acgcttctca aatctgtgta atatcggttt caatacagga atgcagggaa tgtatgtcgg
    12121 cggcattata tactgcggct acggcatttt aacgggagct atcagctatg gaactctcac
    12181 agctataact cagctcatat cgcagataca gtcgcccttt gccaatatta caggctatct
    12241 gccgaagttt tacgctatga ccgccagtgc tgaacgcctt atggagatag aggatttcga
    12301 gaacgacagt gatgttaagc caatggatat tgatgaaact cttgattatt atcgcagcag
    12361 attcaaggct atgggactgg ataacgcaga gtttgcctac tatccgtcag gtgacagtgt
    12421 tcgtcaactc agcaaagata cgatgcctgt tgtgctgaaa gacatcagcg ttgaaatagg
    12481 caagggacag tatgtggctt ttacaggtca cagcggctgc ggaaaatcaa cagtattgaa
    12541 gctgttgatg tgcatttaca agctcgacgg cggcagacgc tacataatcg ataaaagcgg
    12601 caataccgag aagctttcag caaagtttca ccgtctgttt gcatacgttc cgcagggaaa
    12661 tcagcttatg agcggtacta tccgcgatgt ggtctgcttt gccgataaga gcggacttca
    12721 cgacgataag cgtataaacg aagcattgaa aatagcctgt gcttatgaat tcgtcaatga
    12781 acttgatgac ggcgttgata ctcttctcgg tgagcgcgga acaggtctct cagagggcca
    12841 gatgcagcgt atagctattg caagagctat atactcgaag tgccctatac ttctccttga
    12901 cgaagcaact tccgctcttg atgaagctac tgagagaaaa gtccttgaaa acctgaaaaa
    12961 tatgacagat aagactgtag taatagttac acatcgtcct gctgcacttg atatatgcga
    13021 caggatactg caatttaccg ataacggagt gatagaaaat ggaaaagcgt gaatttcgca
    13081 agaatgcagc ggatatgata tatcttaccg cctgtgctat aaataacaaa aagccaagac
    13141 aggagcgcat tgacaacctt gatctgccga agctgtttga ggtatgccag aaccatatcc
    13201 ttacagcttg tgttgcttat gcgcttgaat cagttggcat taaggataac gagttcacac
    13261 aggcaaagga aaaggctatc cgtaagaata tccttcttga cgttgagcgt gggaatatac
    13321 tccgcagact tgaagccgaa aagatttggt atatgccgct gaaaggcgct attctcaaag
    13381 actggtatcc taagctcggt atgcgacaga tgtcagataa tgacattttg tttgatatta
    13441 accatcgaaa cgatgtcagg aatatcatga aagaatttgg atttgaacta aaggctgaac
    13501 gagaagtagt tgatgaatac cttaaaaaac ccatatataa cattgaaatg catggagaac
    13561 tattcatgga gtatcaggtc ggttctatgg ctgactacta tcgtggaatc aaggaaagaa
    13621 ttctgaaaga cgataataat gaatttggtt atcacttcag taatgaagag ttctatttgt
    13681 ttatgcttgc gcatgagtac aaacacttta cactcgatgg aacaggtgta agatctcttg
    13741 tggatacata catattcctg cgtaagttca aatgctctct ggactggaac tacataaata
    13801 cagagcttga taaactcggt attgcagagt atgagaagca aaaccgtgag cttgcaataa
    13861 aagtatgcac attgaagcag cttacgcttg aagataaaaa gcttcttgac tactatgtta
    13921 tgtcaggaac ctatggcaat aaagagaata ctttgaaaaa tagtattaaa tatcgaggca
    13981 aaggttctaa acttggatat atgctgtatc gcctttttcc gcctatgagc tttttggaag
    14041 tatctgtacc gtgggtaaag aagagcaagc ttcttatacc accagcgtat atctacagat
    14101 tttatcgttg tgtgacaagc agcaaaaaat ctgtagaacg tgaggtaaag cagctcggaa
    14161 agacataatt taaatctgat atttttaacc atataaacct aaaggcgcca aaacagttgc
    14221 atgttaacag cttcaattgc tgtctccccg tcatggggag gctcttctta tatataagcc
    14281 ggactcaaga agatcaaaca ttggaatcta tctcatttga aaaataaaaa tcgtcgtcga
    14341 attcttcaaa gctaaattcc gcgtcgctga agagtgacaa gtcttcagtg ctataaaaac
    14401 caaagtcatc ttcatctccg gtttctcttg gtatacatag ttgatacaat gtttgaagta
    14461 tactgctcca tcaccgttat tagtgaccct ttttgtgtta aaatgtccat attttattag
    14521 cctctctttc aaggtaagtt gcgtccttct ccgaaaaatg cttcattcta cgaacagcct
    14581 cattcgcgta gttctgaaac tccgctatca gataactggc ttgaggtact tgaggaagtt
    14641 agctgtggaa agaaaagacc tgtggaggcg atgcgggaac tgggtatctc tcggtcacat
    14701 tattatcggt tataccaaag gagctgataa tgtggaaata tattcagatc aggataaaag
    14761 gtttatatca gtatggctaa ctaatgaaga acaaaaacac tgcgaccgaa aggctcacac
    14821 tgcgcagctt ttaaaatatg cagataatcc taaatgcaag gtcgtatatt tcctttctgg
    14881 aaaagatgat ctttatcaat gtactgaagg ttcgctgctc agaaatcttc atctgagata
    14941 agagcctgag aattactgaa atagccaact gtgatttgat ttcacagttg gctgtcattt
    15001 tactttatct tctattcaag tgtagaggtt ggaattcaat tgttttctat gatcttactg
    15061 ataatatcag tcgctttaaa gatagctgtt ttttcattag gattcaggta aacatcattc
    15121 agcttcagct tggaatactg caaatacgtg tcttctgcct cagagaccag aagcttagta
    15181 taatagtgtt cccaactgaa atattccgag ctttcaagaa agtcctccgt ctgcaataac
    15241 aagcagcttt tttccttcat tatcagtaac ggtgcgttta atttttgtta taccgcctgc
    15301 actaacgcag tcgatagtat caggcacaac tgctttgaag aaatcgtatc ctgagtttga
    15361 atcttaaacg ataaccagtt cagcaggggc atctgttttg tgaccttcag cagtataaag
    15421 ctgatagaag gtgttgtacg ttttacgcat atcagcgtat cttcaagaag tatgaatacc
    15481 gtatatctcc tcagcagagt aggggagatt agtaagtttt tcccttgtta tgataacata
    15541 ataattattg gtcgtctgta tttttttgca aagtcatcgg atttgacgat agtattttct
    15601 tcatcgatga atatgatgct atcgctgacg ctgttcagaa ccgattccca gttggaattg
    15661 ttaatggtca gacatctttt agcacaggat atctcgatac ctgagtccgc accaagtctg
    15721 tcgtaagtat caatgagcga tacaagggtg gtcttgcctg attcatcgaa aagcatgagt
    15781 atcagcgttt ttactccgcc ggacagttcc ttgactgaaa ttgagccgag aacaggactg
    15841 tctattactc ttgcacctgc aacgtctgat ttgtcaatat cctttatcat ttttacactg
    15901 cgaggatagg tgatccactc gtcctcatag gtattatcaa aatacgtcgg agggtgatat
    15961 atcgaattat ctgtatctcc gaaaactatt ttcagcatga ctccacctct tccgagagtt
    16021 tattatgtta ctatcataaa cgattatggc aatattttca agaggctgag taatttttct
    16081 ttgctgtatg taccctttta caaatctcgt ccatagcttt gcagaattcc atatctggtg
    16141 tcaatgattt cagcaagggg tcgccctctc tgatacgcat ggttcgccgt atttccttag
    16201 ggataacgac tcttccgaga tcatctatac gtcttacgat acctgttgct ttcataataa
    16261 aacctccgaa aaaataaagt ttgtgggaat agtttgtgca tagtttgaaa gattattcat
    16321 ttatggaact aagctgaaaa ttaagtttag agtaaaaatc agataatgtt caaagcctcc
    16381 tgtgttgaag caatgctatc aggaggcttt ttttaataac ggtgtaaaaa aatgataatg
    16441 tgaacaatgc attttaggga tttaacaatt tttgagcaat tgcagaaatt aaattttaaa
    16501 gctccggaca tataccatta gtaaaatatt attctgaaat aatttggcaa agccgagaga
    16561 taggggagta tatgctcata tgtctttttt tatcggcaga tatacagaaa tcaaatacga
    16621 tcttgttttg tccgaattgt aattttttta gtgctatttt aacagtgata gctatggaat
    16681 ttttgtgaaa aatgccaaaa aaagcggctg taacctaata tgccattttt tgcacttgca
    16741 tttttttttg tctgacggta taattataaa gtgtactgct atgacattat aaatcaaaaa
    16801 tgttaataaa ttaattcttg acagtcggaa tgcttggata atagttgata ttgctgcatt
    16861 tcttcaggtg ataacaaggc ggcgatttta ataactttct gtcatttaag tctgtcggta
    16921 tatgttttat ttcgcggcag tatattgggt cggtatttgc tggataatta gcaaaaatat
    16981 aacgatttga ggaatacaga tgtttgtaaa aaagaatatc ataaaaccgt ttgaaaacaa
    17041 aatatggctt tcatcaccaa caatgcacgg tgatgaacag aaatgggtaa acgatgcatt
    17101 tgaaaagaac tggataacta cagccggtga aaatgtcaat gaggttgaga ggcttgttgc
    17161 tgagtataca ggtgtaaaat atgctgtggc actctcatgc ggaacagctt ctctccacct
    17221 tgctacaaag cttgcaggag aaaagctcta tggacagcct aagccaaact gcggaacact
    17281 tcagggacac aaggtgtttt gctctgatat gacttttgat gctaccgtaa atcctgttgc
    17341 atatgaagac ggagaggctg ttttcattga tacagagcct caaacatgga atatgtgtcc
    17401 gaaggcactt gaaaaagctt tcgagatata ccctgatgta aagcttgtgg tagttgctca
    17461 tctttacggt attcccggaa agatcgacga gataagaaag atctgcgata agcatggtgc
    17521 tcttatagtt gaagatgctg cggagtcatt cggtgctaaa tataaaggca gggaaacagg
    17581 cagctttggt gattactgtg ctatcagctt caacggaaat aagataatta caggctcatc
    17641 aggcggtatg ttccttacta acagcaagga cgatgctgac aagatacgta aatggtcgac
    17701 acagagccgt gaagatgctc cgtggtatca gcatgaggag atcggctata actaccgtat
    17761 gtccaacatc atagcaggtg ttgtgcgcgg tcagataaaa tatattgatg agcatattgc
    17821 tcagaagaaa gcaatatatg agcgttacag agaaggcttt aagggacttc ctgttactat
    17881 gaatcctttt gatgaaaaaa acagtgagcc taattactgg ctcagctgtc ttctcataaa
    17941 caaagaagca atgtgcaggc aggttcgcag tgagaacgag ccgatgtata ttcccgagca
    18001 tggaaagtct tgtcctacgg agatacttga tacactttta aagtacaacg cagaaggccg
    18061 tccgatatgg aagcctatgc atatgcagcc tatatatcgc atgaacggtt ttgttaccgc
    18121 aaatggcaat ggcagaggac agtctaatgc ttatattgac cgcggtgagg ctgttgatat
    18181 aggagcagat atctttgaga gaggcttatg tctcccgagt gataacaaga tgactgctga
    18241 acagcaggat ataataatcg aacttatcag gagttgtttt gaataatgta tgcaaagtat
    18301 tttaagcgta tgtttgactt tatactttcg cttggtgcga taatagttct ttttccggtc
    18361 ctttttctgc tcactgttgt gggagcagtt gcaatgggcg gtaatccttt ctttacacag
    18421 gaacgtcccg gtaagaacga gaagatcttc aagcttgtaa agttccgtac aatgaataac
    18481 aagagggata agcacggaaa gcttcttccc gatgaaaaga gacttacttc ttatggtaag
    18541 tggctcagaa gtacaagtct tgacgagata cctgaattat tcaatatcct taacggcgat
    18601 atgtcgatta tcggacctcg accattactt gtgaagtatc ttccttacta ttcaaaggca
    18661 cagcatcatc gccatgatgt tcgtcctggc ttaaccggct atgctcaggc acatggaaga
    18721 aatgcatcta cttgggatga acgctttgaa tatgatctta aatatgttaa gcacattact
    18781 tttataggtg atgtaaagat cataatagat actgttaagg cagttctcaa aaaagagggt
    18841 atttctgctg aagggcaggc aacaatgggc gacttcattg attatgtaaa tgagaaaaga
    18901 gcaactgtaa gcgaggtgta acttttgcag actgaaaatt cacttataag cgttatagtt
    18961 ccaatatata aaatagataa atacatagga atatgtattg aaagtcttat aaatcagaca
    19021 tacgataatc tggaaattat actggttgat gacggttctc ctgacagatg ccctgaaata
    19081 tgcgacttgt atgctaagaa ggataaacgt atcaaagtta tccacaaaga gaatggcgga
    19141 cttgtttcag cgcgtaaggc tggattactt gtttccaatg gtgaatatat cggctatgta
    19201 gacggtgacg actgggtagg agcaggcttt tatgaagcat tgtatactgc tattgttaca
    19261 agtaatgctg atattgtttg tgccggacag agccgtgatc tttttgacag aagtgtacat
    19321 tttacaaaca gcttgccttc agggatatat gaaggtacta agcttgaaga tctgtacagg
    19381 aatatgattt ctaacggtga gttttatcgt cccggagtaa ccacatatgt gtggaacaag
    19441 cttttcaaaa gagaagtttt aatggaagct cagctcaatg ttgatgacag aatctcaatc
    19501 ggagaggatg gagcggtgac ttatcctgca ttattagctt caagaaaagt gtgcattact
    19561 gataattgcg catatcatta tcgtcagcga gaggactcga tgcttaaaaa aagtgaatca
    19621 tttgcaaatg aggcaaaaaa gctgagatac ttgtatgatt atcttatgga ttttgcaaaa
    19681 aagcatgata ataagtatga tcttatcaag cagataacag attatgttct tagtatatgc
    19741 ataatccgtt caggcggaat tcttgatgca acagtaacag aaactgagtt taccccgtat
    19801 ggttctaaga tcgacggaaa gaagattgtg atatatagtg ctggaacttt tggccagcag
    19861 cttatgaatc gtttccttga gaactcaaga tgtgatgttg ttggttgggt tgatgacgac
    19921 tattgggagt acaggcgctg ctgtatggac gttgatccgg ttgaaagtat cacaaagctt
    19981 gattatgatt atgttcttgt cgcaacggtg gataggatac ttgccaagaa tattagtaac
    20041 agactgcttg actatggaat gagtaaagat aagatactta tagtaagctg tgaagaatct
    20101 atcagagaag aattgcttga acgctatttg aattgtaagt aaggtaagga tatgaatgat
    20161 acagcaataa gaattctttc cgccaaaaac ggagagacca gcttgttttt tatcggacaa
    20221 gctggattta taataaaaag taaaaacgga cagcttttag g
//
