LOCUS       NZ_KI912489.1          24243 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KI912489.1 Ruminococcus flavefaciens ATCC 19208
            L870DRAFT_scaffold00001.1, whole genome shotgun sequence.
ACCESSION   NZ_KI912489
VERSION     NZ_KI912489.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:56:51
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 499254
            Orig. end    :: 523497
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24243
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[509254:513497]"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14243
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     cand_cluster    1..24243
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..24243
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="3"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     CDS             2246..4555
                     /locus_tag="ctg1_434"
                     /transl_table=11
                     /translation="MFCKSEEWQVNTMKLKRSAAAFIAAATAVIPFSSGNVSLSAPLSA
                     AAEEQTVKAALPQWIPSDFGTALEFRNTYGATHIQDGFVCIVFSEKAGKVSEDDIPRYD
                     IRTTEGIMKELKRTVYSSSDSDTWYEVAVYSEPQKQGKFEAALVDTWLKSSELDLGYNH
                     AVAYYSFDIDEGKNITETDIYSWLPDCITEYKDYKNKNGSVSAKDEFVVFCLDYSAGTP
                     YKWLEAGDNSSNLRHYRTEDCSRKTAVTLDGGSINELQVYKAEKDGSAKIVYNYAPSYD
                     YGEVEVEKTLIADCTVTDGAKKVTLNDSYVNEADFSVSQYSIYSGDLTVSSYSIYNKFA
                     ESKSAVITSKDELKAFLKTYLNEKPLDKFVSQYSDSFFENNVLMLNTYLDPYQGRIFKH
                     GLKGVQYKDGKLVIDFTSVINAQRMRTSCFDILKLTVPKEEYKEADAVWQNEEILNYDL
                     KRISVIDEDTGEPIEIPYGTVLELFGNTMKYIEGSNPYYWDVITSEWEKLDINEEYLPY
                     GYELSKTDPKEVKNYGNNTADIIFKVKKKEPVKVKYTVDKISTITQGLFVEEAFGGFKP
                     VAVSSKNELTEYLSHYITEEYQKKLFSEYDDDFFKENVLLFNFMIDSTASRKIELNDTV
                     FSKDNISVYYTAPSTDFGICNTDYLWALQVTVPKSGYSGQKIEWKCMGDANGDGSFGIA
                     DIVTLQKWLAASSDTELSDLKAVDICEDDVIDVFDLVSMRKKLIEVHQLDKPVTYGIEA
                     QYVRTNGYVDGAERIY"
     CDS             4578..4850
                     /locus_tag="ctg1_435"
                     /transl_table=11
                     /translation="MKSAEFNDAVEKYNDNWFNSHKLMIVLLEESSGSVSHGVTSVTNR
                     SVTINRTVPEVGTCDMAEWHIFIEYPETANISDNFSVEFTNTYLR"
     CDS             5061..6440
                     /locus_tag="ctg1_436"
                     /transl_table=11
                     /translation="MKMKKAIPFIMSLAIVGSCCMFNNTVNDRCSAITAVTIVEQGTYE
                     VDENTSFEYKVTENDDTYIGRYTGTATEVVIPSEINGKKVTGISGNSFYNRADVTSITI
                     PDGITKISMSAFEKCTGLTSITIPEGVEEISHSLFMDCSSLKSVTLPDSIKYIDYEAFK
                     NCTALESINIPDGLEYVMPDAFTNTKWYDDQPDGMILLGKTVYKYKGTMPDNTSIVIPD
                     GIKCIGGDAFLGCTGMTSVTIPDSVGLIENRAFSGCTGLTSVTIPDSVLEMGHDIFEDC
                     TGLTSVKLPEGIKYFAYGTLKGCTGLTSVTLPSSLLAVGLETFEGCTGLTSITIPDNVT
                     DILDNAFKDCTDMTKIVIPKNVSYIHESVFSGCTNLTIYGYKGSEAEKHAKDNNIKFVA
                     LDAETTQQATKTTAKAATTTKAATAKSNSPQTGDKGSAGIITAGFAASALSIISFKKRK
                     K"
     PFAM_domain     5322..5627
                     /aSDomain="LRR_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13306.8"
                     /description="BspA type Leucine rich repeat region (6
                     copies)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_436_0066"
                     /evalue="9.60E-30"
                     /label="ctg1_436"
                     /locus_tag="ctg1_436"
                     /protein_end="189"
                     /protein_start="87"
                     /score="103.3"
                     /tool="antismash"
                     /translation="ISGNSFYNRADVTSITIPDGITKISMSAFEKCTGLTSITIPEGVE
                     EISHSLFMDCSSLKSVTLPDSIKYIDYEAFKNCTALESINIPDGLEYVMPDAFTNTK"
     PFAM_domain     5703..6008
                     /aSDomain="LRR_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13306.8"
                     /description="BspA type Leucine rich repeat region (6
                     copies)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_436_0067"
                     /evalue="4.40E-23"
                     /label="ctg1_436"
                     /locus_tag="ctg1_436"
                     /protein_end="316"
                     /protein_start="214"
                     /score="81.7"
                     /tool="antismash"
                     /translation="NTSIVIPDGIKCIGGDAFLGCTGMTSVTIPDSVGLIENRAFSGCT
                     GLTSVTIPDSVLEMGHDIFEDCTGLTSVKLPEGIKYFAYGTLKGCTGLTSVTLPSSL"
     aSDomain        6345..6437
                     /aSDomain="TIGR01167"
                     /aSTool="tigrfam"
                     /description="LPXTG_anchor: LPXTG cell wall anchor domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_436_0018"
                     /evalue="1.70E-05"
                     /identifier="TIGR01167"
                     /label="ctg1_436"
                     /locus_tag="ctg1_436"
                     /protein_end="459"
                     /protein_start="428"
                     /score="23.3"
                     /tool="antismash"
                     /translation="PQTGDKGSAGIITAGFAASALSIISFKKRKK"
     CDS             complement(6491..7207)
                     /locus_tag="ctg1_437"
                     /transl_table=11
                     /translation="MLLQYYKCEQKKFLYQKWNVIVMLGLLVFVPVMAITLDSYTGGTG
                     VTLTKSKLIEGFYLGQAGYAVLTALYFGYEYQKSALRTSLLSTPKRGMFLTAKLLCILT
                     WSVILLLANTIFSLAAIAMSSSENLGIGEALSLLLPDYLSTLEIVIITSALVILTRSMI
                     VSMAIMVSLVLGLGNLLLQYSSEMKYLPVLSTMNSFFVVRVPQYLAINEGTAVQALWGA
                     ALLMIAFLVFNRRYVR"
     PFAM_domain     complement(6692..7189)
                     /aSDomain="ABC2_membrane_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12730.9"
                     /description="ABC-2 family transporter protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_437_0068"
                     /evalue="7.10E-07"
                     /label="ctg1_437"
                     /locus_tag="ctg1_437"
                     /protein_end="172"
                     /protein_start="6"
                     /score="29.4"
                     /tool="antismash"
                     /translation="KCEQKKFLYQKWNVIVMLGLLVFVPVMAITLDSYTGGTGVTLTKS
                     KLIEGFYLGQAGYAVLTALYFGYEYQKSALRTSLLSTPKRGMFLTAKLLCILTWSVILL
                     LANTIFSLAAIAMSSSENLGIGEALSLLLPDYLSTLEIVIITSALVILTRSMIVSMAIM
                     VSL"
     CDS             complement(7208..7996)
                     /locus_tag="ctg1_438"
                     /transl_table=11
                     /translation="MKNFVNNLYSELLKLCYTKVCKIVTLLVIAAQSMLAYISAKQTLS
                     VGLDAVPTETNQLAEPMPPLEYMGFDVVMFATIPMIVLGALFGASEFKLHSLRTSLLSF
                     GSKRNLFVSKSLAVTIISFFISLISTTLTITITHFTFGDQGLKPLVFNATVWKFILFST
                     VSLTLLTVLSYAIAFLCRTAVVPLLFLIIQAYNVGNMLAEKFEVCKYLPVSLSNGLIPT
                     SESVLSGMPMKNIICLLCWTLFFVSAGYILFRKIDLQGEY"
     CDS             complement(7996..8709)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 164.3; E-value:
                     6e-50)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_439"
                     /transl_table=11
                     /translation="MEQSIKISNVNKKYGNKEILKDVSFEAQKGRITAFLGPNGAGKST
                     TLRILLGLDSADSGTAFIGGQNYAKWNEPLKKIGASFDGVGSPNDRTVYQHLRIISVSN
                     GIPKKRIDEVMEITGISHKASSQVGSLSLGEGQRLGIAAALIGDPQFLIFDEPTNGLDP
                     NGIRWFREFVKKQAKDGKTVLLSSHMLSEVEAVTNDVVIINHGKIVTKGTLDTVMKDIS
                     SLEDLFFNLTDEGNC"
     PFAM_domain     complement(8233..8652)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_439_0069"
                     /evalue="1.20E-25"
                     /label="ctg1_439"
                     /locus_tag="ctg1_439"
                     /protein_end="159"
                     /protein_start="19"
                     /score="90.7"
                     /tool="antismash"
                     /translation="LKDVSFEAQKGRITAFLGPNGAGKSTTLRILLGLDSADSGTAFIG
                     GQNYAKWNEPLKKIGASFDGVGSPNDRTVYQHLRIISVSNGIPKKRIDEVMEITGISHK
                     ASSQVGSLSLGEGQRLGIAAALIGDPQFLIFDEPTN"
     CDS             8886..9332
                     /locus_tag="ctg1_440"
                     /transl_table=11
                     /translation="LKIKLIVNPEHYEAISDELNRLGIEISDNADLILTERNASISYLI
                     GKRNEEIYRLKTSDISHIESFAHEVIAYTDEGEFRINERLKTLSGLLDPEIFIRISNSV
                     IISTEHIKSIKPGFTQKFIVTMQNGAVVDVTRTYYYFFKEFLGI"
     PFAM_domain     9036..9323
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_440_0070"
                     /evalue="8.20E-18"
                     /label="ctg1_440"
                     /locus_tag="ctg1_440"
                     /protein_end="146"
                     /protein_start="50"
                     /score="64.5"
                     /tool="antismash"
                     /translation="EIYRLKTSDISHIESFAHEVIAYTDEGEFRINERLKTLSGLLDPE
                     IFIRISNSVIISTEHIKSIKPGFTQKFIVTMQNGAVVDVTRTYYYFFKEFL"
     CDS             9343..9948
                     /locus_tag="ctg1_441"
                     /transl_table=11
                     /translation="MKLFYSLILLLIISVIFAVVLTFVYIILYNNYLSKRVKNGIKTKD
                     GGRRHVEPFNFFLICFFVILILSCLVLSVNNDKKLNAPESPGFEICADNSYADSFSCSS
                     ELPGYTRYEKVVDDISCVYYINNNKNSAFPAMYLYIGYKGKYSFTYYSDETKKASSSDI
                     SISGENAGWYALNDMPDSDKLFLDIKTGSASNTIEIKL"
     CDS             complement(10001..12241)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 315; E-value: 1.6e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_442"
                     /sec_met_domain="PF13471 (E-value: 2.2e-21, bitscore: 71.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLQLTKEKYIHVGFKLKFLAAFALLISAPLILFSPKRIEKILTA
                     ITKKKPLATLTQAETARGAICYVSKKCRNQDRCLKRSIAATVLLALQGKRVSWCTGYCM
                     DPFRAHAWIEVYGRPAGEPKEVDSFVKVIKTPDETEVPKGMEMEENEKKPEEIENNKEI
                     HVKIRDLFALVSDKKKYFLIVMILGVIASIFTLIQPDLVSDIINNVNTDTNISSKIGIL
                     IGVILGSTIITTLQYYLLQIISEEAVFRSRKDLISHILQLPIANYSKWSSGDLISRLTG
                     DTSKLRAGIIQSTVALSSGLLLAIGASIGLLLKDFTLFLVTIISIFVSFVLIALMSVII
                     QKASYEAQKGMGKLSGKLGQSLRGIRTIRSTNETKNELKKTVDEAENVKSLSLKLAKYQ
                     AFMTPVSNLGLQLCGMAVIGIGGWRVSKGEMSVGDLTSFVLLLYIAISPFQQIFSTIST
                     LADSVGSLKRIKEISSMPLEDQFDIIIDNKKETDDHAITFNNVTFSYVQHVLGQETEEF
                     DENVILRDVSFSINNGECVAIVGPSGAGKSTVLQLIERFYELNNGTICVYGKDYHTMSR
                     EELRSKITYIEQNAPLLSGTIYDNLKVGNNNVTEEKCMEALEKVNLSYLVTNRSKGLYS
                     VIDENGTGLSGGEKQRLAMARALLSDTDIIILDELTSNLDSINERIIKDVVEELRGTKT
                     IIMVAHRLSTTMNADNIYVLEHGRIVGKGNHDELIKTVPLYYELAKEQMLVS"
     PFAM_domain     complement(10229..10675)
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_442_0073"
                     /evalue="2.40E-31"
                     /label="ctg1_442"
                     /locus_tag="ctg1_442"
                     /protein_end="671"
                     /protein_start="522"
                     /score="109.2"
                     /tool="antismash"
                     /translation="LRDVSFSINNGECVAIVGPSGAGKSTVLQLIERFYELNNGTICVY
                     GKDYHTMSREELRSKITYIEQNAPLLSGTIYDNLKVGNNNVTEEKCMEALEKVNLSYLV
                     TNRSKGLYSVIDENGTGLSGGEKQRLAMARALLSDTDIIILDELT"
     PFAM_domain     complement(10904..11701)
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_442_0072"
                     /evalue="1.60E-35"
                     /label="ctg1_442"
                     /locus_tag="ctg1_442"
                     /protein_end="446"
                     /protein_start="180"
                     /score="123.2"
                     /tool="antismash"
                     /translation="FLIVMILGVIASIFTLIQPDLVSDIINNVNTDTNISSKIGILIGV
                     ILGSTIITTLQYYLLQIISEEAVFRSRKDLISHILQLPIANYSKWSSGDLISRLTGDTS
                     KLRAGIIQSTVALSSGLLLAIGASIGLLLKDFTLFLVTIISIFVSFVLIALMSVIIQKA
                     SYEAQKGMGKLSGKLGQSLRGIRTIRSTNETKNELKKTVDEAENVKSLSLKLAKYQAFM
                     TPVSNLGLQLCGMAVIGIGGWRVSKGEMSVGDLTSFVLLLYIAI"
     PFAM_domain     complement(11846..12154)
                     /aSDomain="Transglut_core3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13471.8"
                     /description="Transglutaminase-like superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_442_0071"
                     /evalue="4.20E-19"
                     /label="ctg1_442"
                     /locus_tag="ctg1_442"
                     /protein_end="132"
                     /protein_start="29"
                     /score="68.7"
                     /tool="antismash"
                     /translation="PLILFSPKRIEKILTAITKKKPLATLTQAETARGAICYVSKKCRN
                     QDRCLKRSIAATVLLALQGKRVSWCTGYCMDPFRAHAWIEVYGRPAGEPKEVDSFVKV"
     CDS             complement(12241..12495)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Thurincin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_443"
                     /sec_met_domain="PF05402 (E-value: 2.3e-16, bitscore: 55.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.3e-22,
                     bitscore: 75.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PqqD_RRE (E-value: 2.4e-07, bitscore:
                     25.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="Thurincin_rSAM_RRE (E-value: 7.6e-08,
                     bitscore: 27.7, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLFKRKIELKITEQENGAIVFDKTHGVYFQTNNVGTFILQQLSG
                     GKNSAEITDAVAENFNIDRTQAETDVNEFLDSLKKAGIA"
     PFAM_domain     complement(12247..12438)
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_443_0074"
                     /evalue="2.70E-14"
                     /label="ctg1_443"
                     /locus_tag="ctg1_443"
                     /protein_end="83"
                     /protein_start="19"
                     /score="53.3"
                     /tool="antismash"
                     /translation="IVFDKTHGVYFQTNNVGTFILQQLSGGKNSAEITDAVAENFNIDR
                     TQAETDVNEFLDSLKKAGI"
     CDS             complement(12498..14243)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 55.8; E-value: 5.2e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_444"
                     /sec_met_domain="Asn_synthase (E-value: 1.2e-18, bitscore:
                     63.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LESKNIKEFTLGTSGNKKLMILNKDSYTFRDLGNKKLYYPEKYDK
                     EIENNIEKMIKLEKESLITDLQDRFLTGVFALEVDSDWIIFGPFLDTSLSYCKTESEIL
                     ISDSAFDIAYKKQFKVSKSSISAYLVTGLPFEPFSNMSFWDEISKINPFRILKISSGNI
                     TECEMTNAFKVDHDIDKVTKDLRDTIISNIYNQNSQFDSVSCDVSGGVDSASIAYVVNK
                     ISGQPMIFHAESDESANSDTKWAQYIADDLRIELNKLPSIDKNSSRFSVDKEYIGSNVP
                     DSPLLWGDTEGYVKEMLCKLPEKDKHLHMIGIGGDELFTYIPSVPWSIIREEGVVRSIP
                     LIFKYCILSRRSFLKCIKDLTNKTSLKDEVKQSIDNGFGSKKKNKRQLSWSEDVIFPSW
                     LTDSAKESAHSKINSLFSNQFYELSDDRSHYQRIQSILFQKEIFSQIVHVAGDEIGWYA
                     PFLDAKVIKTALTLPSRYCTDPQKTKPMLYEALKGIVPLEVFTRGVKGDYSSAFYNDYR
                     AAAAKWMGKTKEFFLSKLDVINHESLDRELSMPSSNFERVDFFMRVCNIERWLRQVNKY
                     IEIGV"
     PFAM_domain     complement(12588..13649)
                     /aSDomain="Asn_synthase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00733.23"
                     /description="Asparagine synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_444_0075"
                     /evalue="3.50E-17"
                     /label="ctg1_444"
                     /locus_tag="ctg1_444"
                     /protein_end="552"
                     /protein_start="198"
                     /score="63.2"
                     /tool="antismash"
                     /translation="QFDSVSCDVSGGVDSASIAYVVNKISGQPMIFHAESDESANSDTK
                     WAQYIADDLRIELNKLPSIDKNSSRFSVDKEYIGSNVPDSPLLWGDTEGYVKEMLCKLP
                     EKDKHLHMIGIGGDELFTYIPSVPWSIIREEGVVRSIPLIFKYCILSRRSFLKCIKDLT
                     NKTSLKDEVKQSIDNGFGSKKKNKRQLSWSEDVIFPSWLTDSAKESAHSKINSLFSNQF
                     YELSDDRSHYQRIQSILFQKEIFSQIVHVAGDEIGWYAPFLDAKVIKTALTLPSRYCTD
                     PQKTKPMLYEALKGIVPLEVFTRGVKGDYSSAFYNDYRAAAAKWMGKTKEFFLSKLDVI
                     NHESLDRELSMPSS"
     CDS             complement(14363..14488)
                     /gene_functions="biosynthetic-additional (lassopeptides)
                     predicted lassopeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_445"
                     /transl_table=11
                     /translation="MTYNKPSVEKVASFKDNTMGLWYGKFRDIFGAKTYFNLAWN"
     CDS_motif       complement(14432..14488)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MTYNKPSVEKVASFKDNTM"
                     /locus_tag="ctg1_445_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(14363..14431)
                     /prepeptide="core"
                     /locus_tag="ctg1_445_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-8.30"
                     /molecular_weight="2650.0"
                     /monoisotopic_mass="2648.3"
                     /core_sequence="GLWYGKFRDIFGAKTYFNLAWN"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MTYNKPSVEKVASFKDNTM"
                     /leader_location="[14431:14488](-)"
     CDS             complement(14614..14736)
                     /gene_functions="biosynthetic-additional (lassopeptides)
                     predicted lassopeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_446"
                     /transl_table=11
                     /translation="MTYNKPSFEKVASFKDNTMGVWFGKWTDIFGGRAFIHVEW"
     CDS_motif       complement(14680..14736)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MTYNKPSFEKVASFKDNTM"
                     /locus_tag="ctg1_446_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(14614..14679)
                     /prepeptide="core"
                     /locus_tag="ctg1_446_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-10.00"
                     /molecular_weight="2490.8"
                     /monoisotopic_mass="2489.2"
                     /core_sequence="GVWFGKWTDIFGGRAFIHVEW"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MTYNKPSFEKVASFKDNTM"
                     /leader_location="[14679:14736](-)"
     CDS             complement(14833..14961)
                     /gene_functions="biosynthetic-additional (lassopeptides)
                     predicted lassopeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_447"
                     /transl_table=11
                     /translation="MTYNKPSFEKVASFKNSTMGLCFGKWNDIFGGRAIIKIEIGF"
     CDS_motif       complement(14905..14961)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MTYNKPSFEKVASFKNSTM"
                     /locus_tag="ctg1_447_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(14833..14904)
                     /prepeptide="core"
                     /locus_tag="ctg1_447_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-10.50"
                     /molecular_weight="2537.0"
                     /monoisotopic_mass="2535.3"
                     /core_sequence="GLCFGKWNDIFGGRAIIKIEIGF"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MTYNKPSFEKVASFKNSTM"
                     /leader_location="[14904:14961](-)"
     CDS             complement(15194..15322)
                     /gene_functions="biosynthetic-additional (lassopeptides)
                     predicted lassopeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_448"
                     /transl_table=11
                     /translation="MTYNKPSFEKVASFKNKTMGLWFGNFKDLFGGKIYIALSPAW"
     CDS_motif       complement(15266..15322)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MTYNKPSFEKVASFKNKTM"
                     /locus_tag="ctg1_448_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(15194..15265)
                     /prepeptide="core"
                     /locus_tag="ctg1_448_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-10.90"
                     /molecular_weight="2583.0"
                     /monoisotopic_mass="2581.3"
                     /core_sequence="GLWFGNFKDLFGGKIYIALSPAW"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MTYNKPSFEKVASFKNKTM"
                     /leader_location="[15265:15322](-)"
     CDS             complement(15420..15548)
                     /gene_functions="biosynthetic-additional (lassopeptides)
                     predicted lassopeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_449"
                     /transl_table=11
                     /translation="MTYNKPSFEKVASFKNSTMGLWTGKWTDIFGGRAIIKIEIGF"
     CDS_motif       complement(15492..15548)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MTYNKPSFEKVASFKNSTM"
                     /locus_tag="ctg1_449_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(15420..15491)
                     /prepeptide="core"
                     /locus_tag="ctg1_449_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-10.50"
                     /molecular_weight="2561.0"
                     /monoisotopic_mass="2559.4"
                     /core_sequence="GLWTGKWTDIFGGRAIIKIEIGF"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MTYNKPSFEKVASFKNSTM"
                     /leader_location="[15491:15548](-)"
     CDS             complement(15868..15990)
                     /locus_tag="ctg1_450"
                     /transl_table=11
                     /translation="MTYSKPKFEQIASFKKDTLGILFGKKLDVFGSKGIFIWDL"
     CDS             16491..17156
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 145.7; E-value: 2.5e-44)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_451"
                     /transl_table=11
                     /translation="MYKILIIDDDPAIIRLIKNSLSNESYELHTRNSVEDINLCDFMGF
                     DLILLDMVMPNSGIDICKMIRNEIKIPIIFISAKSCEDNIIDCITSGGDDFIAKPFSVK
                     ELKARVKMHLRREERYSKKKTSLRVNDRFIELSDLKVVINDSSFFLTKKEYNIIKLLSD
                     NSNRVFSSEEIYDCVYPLSTDTQIRSISEYIYQIRKKFKPFGLDPIFTVWGGGYCWKK"
     PFAM_domain     16500..16823
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_451_0076"
                     /evalue="1.60E-22"
                     /label="ctg1_451"
                     /locus_tag="ctg1_451"
                     /protein_end="111"
                     /protein_start="3"
                     /score="79.9"
                     /tool="antismash"
                     /translation="ILIIDDDPAIIRLIKNSLSNESYELHTRNSVEDINLCDFMGFDLI
                     LLDMVMPNSGIDICKMIRNEIKIPIIFISAKSCEDNIIDCITSGGDDFIAKPFSVKELK
                     ARVK"
     PFAM_domain     16935..17144
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_451_0077"
                     /evalue="7.60E-14"
                     /label="ctg1_451"
                     /locus_tag="ctg1_451"
                     /protein_end="218"
                     /protein_start="148"
                     /score="51.7"
                     /tool="antismash"
                     /translation="FLTKKEYNIIKLLSDNSNRVFSSEEIYDCVYPLSTDTQIRSISEY
                     IYQIRKKFKPFGLDPIFTVWGGGYC"
     CDS             17141..18217
                     /locus_tag="ctg1_452"
                     /transl_table=11
                     /translation="LLEKISLKCLIVKTFKRIIFQCITFFFALPVGIYILLAFFYMVHI
                     SFPLLSFCNSNFWIIVLSGWIIIISLNSFLLIERIYSDINGLLKKSYNRLNVNPDDRCA
                     FLISEIDEINNCFFKYKEKLYNKFSDELNQKNEFLFLTSISSHDLNSLNTITQGNIELL
                     AGSDLDAQQTEFLEDIKAASDDSQQFIENLIQYLNTFCLERYNMSLCSVYELLSYIKQD
                     NDIITDDPADINKNALAVYDKELRIYAAETLRAFQVAIGCLERYTNNSESCLKVDMCTE
                     RDMCIFSINNMGKPFTQKVLAQYDITSSRRCICDNANESRFIIQLMYVKKILEMEKGSM
                     RLVNIHDHPMIELCLPIM"
     CDS             18420..19928
                     /locus_tag="ctg1_453"
                     /transl_table=11
                     /translation="MLRIANTENGQVRGLPAADPRITSFKGIPFAAPPVGENRWRAPQP
                     AENWEGVRDCFEFAPISVQDTPGLGDDIYCREWHVDPDIPMGEDCLYLNVWTNAKSANE
                     RKPVLVWFFGGAFQWGYTAEMEFDGERLARRDIVVVTVNYRLGALGFLCHPQLTKEQPD
                     APCNFGCLDQQAGLRWVRRNIANFGGDPDNITIAGQSAGGGSVMAQMACMDNEGDFKKV
                     VVMSGMFGSPYTVNDFFLPQSVEQAEKKGERLFEYLGVKTLEEARKLDADYIRSKYSEL
                     RNNGEMFFTIVQDGHFCTQDPMAAFRNGTRIRVPVMAGNTGDEFIEYIHAADEDELSEK
                     AEEYFGGRAEEFFSFPEARVRNDSGYSPISSPELGVKKAFLGDNGQNAPENCYYYRFIS
                     DIPGEDAPGTFHSVDLWFFFETLAKCSRPYEGRHYDLARQMCDYWANFIKTGDPNGFDI
                     NGNKLHEWKPYTDNERNEMLFTSDGAKASTEQSGFVRFLLDTMK"
     PFAM_domain     18429..19439
                     /aSDomain="COesterase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00135.30"
                     /description="Carboxylesterase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_453_0078"
                     /evalue="7.90E-85"
                     /label="ctg1_453"
                     /locus_tag="ctg1_453"
                     /protein_end="340"
                     /protein_start="3"
                     /score="285.8"
                     /tool="antismash"
                     /translation="IANTENGQVRGLPAADPRITSFKGIPFAAPPVGENRWRAPQPAEN
                     WEGVRDCFEFAPISVQDTPGLGDDIYCREWHVDPDIPMGEDCLYLNVWTNAKSANERKP
                     VLVWFFGGAFQWGYTAEMEFDGERLARRDIVVVTVNYRLGALGFLCHPQLTKEQPDAPC
                     NFGCLDQQAGLRWVRRNIANFGGDPDNITIAGQSAGGGSVMAQMACMDNEGDFKKVVVM
                     SGMFGSPYTVNDFFLPQSVEQAEKKGERLFEYLGVKTLEEARKLDADYIRSKYSELRNN
                     GEMFFTIVQDGHFCTQDPMAAFRNGTRIRVPVMAGNTGDEFIEYIHAADEDELSEK"
     PFAM_domain     19578..19871
                     /aSDomain="COesterase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00135.30"
                     /description="Carboxylesterase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_453_0079"
                     /evalue="1.80E-11"
                     /label="ctg1_453"
                     /locus_tag="ctg1_453"
                     /protein_end="484"
                     /protein_start="386"
                     /score="43.8"
                     /tool="antismash"
                     /translation="NAPENCYYYRFISDIPGEDAPGTFHSVDLWFFFETLAKCSRPYEG
                     RHYDLARQMCDYWANFIKTGDPNGFDINGNKLHEWKPYTDNERNEMLFTSDGA"
     CDS             19941..21341
                     /locus_tag="ctg1_454"
                     /transl_table=11
                     /translation="MSKKQAFNPYLPSWEYIPDGEPYVFGDRVYVYGSHDFWNGYVFCM
                     GDYVCWSAPIDDLGNWRYEGVIYPRNADPMNKDGHMCLYAPDVTVGPDGRYYLYYVLDK
                     VGVMSVAVCDEPAGKYEFYGYIHYPDGTRLGEREGDEPQFDPGVITEGDKTYMYSGFCP
                     EGDKSRTGARVVTLDKDMLTVITEPQTIVPGICYSEGTQYEGHAFFEASSIRKVNGKYY
                     FIYSSEVMHELCYAVSDEPLGGFRYGGVLVSNTDLHIDTYKPADMPASRGANNHGSIIE
                     INGEWYIFYHRHTNGTWFSRQGCAEKLTLNADGSFDQAEITSCGLNGGPLEGRGEYPAY
                     IACNIFGRNPELYIGDLNAPRIVQDGKDGDEEIGYISNIKEGTNIGFKYFDCKGITKVS
                     ITTRGYCGGTFAVKTAWDGEELGEIEVENSNVWKKSTADIRIPDGVNAIWFTFKGTGNP
                     SFGSFTMV"
     PFAM_domain     20019..20885
                     /aSDomain="Glyco_hydro_43"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04616.16"
                     /description="Glycosyl hydrolases family 43"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_454_0080"
                     /evalue="9.20E-24"
                     /label="ctg1_454"
                     /locus_tag="ctg1_454"
                     /protein_end="315"
                     /protein_start="26"
                     /score="84.3"
                     /tool="antismash"
                     /translation="DRVYVYGSHDFWNGYVFCMGDYVCWSAPIDDLGNWRYEGVIYPRN
                     ADPMNKDGHMCLYAPDVTVGPDGRYYLYYVLDKVGVMSVAVCDEPAGKYEFYGYIHYPD
                     GTRLGEREGDEPQFDPGVITEGDKTYMYSGFCPEGDKSRTGARVVTLDKDMLTVITEPQ
                     TIVPGICYSEGTQYEGHAFFEASSIRKVNGKYYFIYSSEVMHELCYAVSDEPLGGFRYG
                     GVLVSNTDLHIDTYKPADMPASRGANNHGSIIEINGEWYIFYHRHTNGTWFSRQGCAEK
                     LTLNADGS"
     CDS             21655..22971
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143:sugar-binding lipoprotein (Score: 224.8; E-value:
                     3.9e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_455"
                     /transl_table=11
                     /translation="MKKRRILATIMTAAMFATTLVGCGSDNNSSSGGSSSSGNGGGDSG
                     KVQEITWMFWDDLNATEDLISLGYKETIERFNNDFKGKYHVTPITTNLEEYYNKLNALV
                     AAGDTPDVFIVSPGPQLTDYVEPGVAAPLDDYLNKDGWKDTFTSDAVFTQQTYDGKIYA
                     VPLNTAAACCFYNTEMFEKAGAKVPTNWDEMMEACEKLKAANYTPVTISAGTAWCLSMV
                     AGYLCEAEGVDLSKLADGSASWEDGKLESACNKLLDLSKYFQRTAAGDTNDVATANFYN
                     EEAAILIQGSWAIAQINGSNPDFESKCGVFQFPGVDRIIAKSDSLCMSSTTKNPEGAAA
                     LIKYFTDDTAQKYTAEKGGKIPVTKVQYDVSAAPKQLGYVMDVFGSAKGTFGFYNESMP
                     TTETGAHFDDTMVSVFLGDMKPAEAAKDMEEFYKANCRK"
     PFAM_domain     21874..22710
                     /aSDomain="SBP_bac_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01547.27"
                     /description="Bacterial extracellular solute-binding
                     protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_455_0081"
                     /evalue="7.50E-33"
                     /label="ctg1_455"
                     /locus_tag="ctg1_455"
                     /protein_end="352"
                     /protein_start="73"
                     /score="114.9"
                     /tool="antismash"
                     /translation="ERFNNDFKGKYHVTPITTNLEEYYNKLNALVAAGDTPDVFIVSPG
                     PQLTDYVEPGVAAPLDDYLNKDGWKDTFTSDAVFTQQTYDGKIYAVPLNTAAACCFYNT
                     EMFEKAGAKVPTNWDEMMEACEKLKAANYTPVTISAGTAWCLSMVAGYLCEAEGVDLSK
                     LADGSASWEDGKLESACNKLLDLSKYFQRTAAGDTNDVATANFYNEEAAILIQGSWAIA
                     QINGSNPDFESKCGVFQFPGVDRIIAKSDSLCMSSTTKNPEGAAALIKYFTDDTAQK"
     CDS             23071..23958
                     /gene_functions="transport (smcogs) SMCOG1067:putative ABC
                     transporter permease protein (Score: 248.6; E-value:
                     1.2e-75)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_456"
                     /transl_table=11
                     /translation="MDKLLRNKKALAVFMLPAFILFTLVLFIPIVQSVYYSFCDYKGFT
                     APVFIGIDNYKALLSDKTFGIALKNSIFFLIFSCVSQLIVGLFFAALLTNIKVGRNAFK
                     NIIYLPCVLSSAALGLMWMFIFSPKLGINQLLEKWGVEEPPLWLMDTKGHIILPMWIIA
                     FVALWQYVGQSMMLYMAQISGISKSLMEASYIDGCTKAKTFRYITLPLIKPMIATAMSL
                     NAIGSLKFFDLIYNMTKGGPNHSTEVLATHLYEQGFKYFKYGYASAIGVVLLVLCLIVT
                     LFINKVVKTEQYEM"
     PFAM_domain     23317..23922
                     /aSDomain="BPD_transp_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00528.24"
                     /description="Binding-protein-dependent transport system
                     inner membrane component"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_456_0082"
                     /evalue="1.30E-20"
                     /label="ctg1_456"
                     /locus_tag="ctg1_456"
                     /protein_end="284"
                     /protein_start="82"
                     /score="74.0"
                     /tool="antismash"
                     /translation="LIVGLFFAALLTNIKVGRNAFKNIIYLPCVLSSAALGLMWMFIFS
                     PKLGINQLLEKWGVEEPPLWLMDTKGHIILPMWIIAFVALWQYVGQSMMLYMAQISGIS
                     KSLMEASYIDGCTKAKTFRYITLPLIKPMIATAMSLNAIGSLKFFDLIYNMTKGGPNHS
                     TEVLATHLYEQGFKYFKYGYASAIGVVLLVLCLIVTLFI"
ORIGIN
        1 gattattata gcagttatta cgataacaag aagctttacg ctgtttaagg tgttcgttac
       61 atctttgcct atacaagcac ttacaaatcc gtcagaatca tcaacgtatt tggtgttgaa
      121 tatatccttc attttttcga tgcgtttttc tgtctctgca ttatctgggt ggtcgtcaaa
      181 gtctatctgg aagcccatta cgtttttgac agcactttcg ggaatatatg cgttttcgca
      241 gaatcttcct gtttcgccga gctgtaccat gctctggaaa aatgccgaga caatatattc
      301 ttttgtttca ccatcaagag tgatatttac cttgtcgccg atgccgacgt ctactttgtc
      361 ggcaagctgt tttgtgagag ctatctcgtt ctcgtatttc ggagcatatc cctcggagta
      421 tgtgtaatcc gatgcctttg tgtccttgca gtacatgaat gcagctgttg cttttttgcc
      481 gttagcttcc atcagcggga agagaagcgt ttctgaatga acttttcccg gcatattgtt
      541 ttctgcaagc ttatcttcta tttcgttttc gagctcgctg tatgtactct cacctgtcat
      601 gagccttgat atcatttccg tatcggttat atatgcatca cttggagtag cgcacagtgt
      661 aggcataagc ttttcacttc caagtgtatt tgctgtgttt gcaaggctca ttataagcag
      721 cagacataca gtaaatatag atgtcattat gcagaactgc ttaggactgc tgaatacatc
      781 gtttactgca aggaagcctg tagtgcccag ctttgacttt tcaagacgga ataccccctt
      841 tttcctgaat ctttctcctg tctgaccgct tcttactgcg tctataggtg agagcttctt
      901 tatctttttt gtacagctcc agcagaagag aaggattatt gcgataactg caaggctgca
      961 tatgatacct acaagaatgg gattaccgtt tgcaagcacc atattgtcgc tgaccttttt
     1021 aaggagcata tttccgaaag gcaggctgag cgcaaaaccg ataactgcgc cgatgactgc
     1081 gatgccgaaa tattttacaa ggtacagacc gcggacggaa ttgtttctca gtccgagcgc
     1141 cttcattacg cctatttcgc ggaaatcctc gtttatggtg aagcttatgg taaatctcag
     1201 agttacgaat gagactatca gcaggcagat gcttactatg agaagcagtc ctgctacgat
     1261 actgttcatg atgtatgaag ttctgacgag agtctgatct ttattgaact gtacgtttgg
     1321 caggtctgaa aggtcagagg caagtgcctt cttatcatag ccgttgatgt aaaatatctg
     1381 cgcctgattg ttttcggaag ccttttcgtc tgcggctatt tttgcgtaat cgctgctgtt
     1441 cataagtata cgggaattgc ccatcatttc cgaaccgagg aaagcgtcct ttgcaatgcc
     1501 tgcatatgaa aatgtcagct gggtattgcc tatttttaca tcgaatttgt caccgatctc
     1561 aagatttgaa ctgcttgcaa gagtgcttgt aaagtaagcc gttccttctt ttacttctgt
     1621 aatgatctca ttatcactgt tgaagtaatt gatctgcgca ttatcaattg aaagagcaag
     1681 gaaagtgctt gactgttcta taagcttttt tccgtttcgg gtaacgccct tgtcatcaaa
     1741 gaaaaactga tcctctctgc ggaaatcctt taccgaggat ttctgtgcta tcatatcagc
     1801 tatctcgtca ccgttgtcgc tgacgttgat gatgaagtgg tcgctcaggt ttgctttttc
     1861 aaaataattg tcaagaccgt ttattaccga cattatgttg ttgacactgc ttgcggcaaa
     1921 catggtcgca agtatgacaa acatcagaag tatgacattc atggtctttt ttcttttaag
     1981 atctctcttt agtattctca gatacatatt aacccctcgc tttctgtgat tatatcttag
     2041 catgggaatt attaaataat ccttaaatgg atatttcatc ggaaataacg tgtttttatt
     2101 cgtttgccta taatgattgt accattaatg cttaataaat tcaagtggga ctcatgccgc
     2161 agctgcgttg ttttacaaat atgtgaacaa tggctgaaat gcttgatttc acggaggaac
     2221 cgtgttataa tgtggacagg cagagatgtt ctgcaaatct gaagaatggc aggtgaacac
     2281 aatgaagtta aaaagatcag cggcggcttt tatcgcagct gcaacagcgg ttatcccgtt
     2341 ttcatcaggc aatgtatcat tatccgcacc tttaagtgca gctgctgagg aacagactgt
     2401 aaaagctgca cttccccaat ggataccgag cgattttggt acggcactgg aatttcgcaa
     2461 tacctacggc gctactcata ttcaggacgg ttttgtctgc atcgtattca gcgaaaaggc
     2521 tggcaaggta tccgaagatg atatcccacg ttatgatatc aggactacag aaggcattat
     2581 gaaggaactg aagcgtacag tatactcttc ttccgacagc gatacatggt atgaagtcgc
     2641 tgtatattcc gagccgcaga aacagggaaa atttgaagct gcgctcgttg atacatggct
     2701 gaaatcatcg gagcttgatc tcggctacaa tcacgctgtg gcttattatt cctttgatat
     2761 tgatgaaggt aaaaacatca cggagactga tatttacagc tggcttcctg actgtataac
     2821 ggaatacaag gactataaga acaaaaacgg ttctgtatcc gcaaaggacg aattcgttgt
     2881 gttctgcctt gattattcag caggaacgcc ctacaaatgg ctggaagccg gtgataattc
     2941 gtcaaacttg cggcattacc gcacggagga ttgcagcagg aaaacagccg tgacgcttga
     3001 cggcggaagt ataaacgaat tacaggtata caaggctgaa aaggacggca gtgcaaagat
     3061 agtctataac tatgctccgt cctatgatta cggagaggtc gaagttgaaa aaactcttat
     3121 tgccgattgt actgtaactg acggtgcaaa gaaagtgacc ctcaatgatt catatgtaaa
     3181 cgaggctgac ttttcagtct ctcagtacag tatttattca ggcgacctta ccgtttcatc
     3241 atacagtatc tataataaat ttgcggagtc aaagtcggct gtcattacat ctaaagatga
     3301 gctcaaagcc ttccttaaaa cttatcttaa tgagaagccg cttgataagt tcgtttctca
     3361 gtacagcgac agctttttcg agaataatgt gctgatgctg aatacctacc tcgacccgta
     3421 tcagggacgt atcttcaagc acggactgaa aggcgtacag tataaggacg gcaagctcgt
     3481 tatagatttt acttccgtta tcaatgcaca gcgtatgaga acatcatgtt tcgatatatt
     3541 gaagcttaca gttccgaaag aggaatacaa ggaagcagat gctgtatggc agaatgaaga
     3601 gatactgaat tacgatctca aacgcatcag cgttatcgac gaggatacgg gcgagcctat
     3661 agaaataccc tacggaacgg tattggagct tttcggcaac accatgaagt atattgaagg
     3721 cagcaatcca tattactggg acgttataac ctcagagtgg gagaagcttg atataaatga
     3781 ggagtatctg ccttacggtt atgagctttc aaagacagat ccgaaagagg taaagaatta
     3841 cggaaacaat accgcggata tcatattcaa agtaaagaaa aaagaacccg ttaaggtgaa
     3901 gtatacagta gataagatat caactatcac gcaaggactt tttgtggaag aggcgttcgg
     3961 tggctttaag cctgtggctg tatcttcaaa gaatgagctt acggaatatc tgtcgcatta
     4021 tattaccgaa gaatatcaga aaaagctgtt ttcagagtat gacgatgatt tctttaagga
     4081 gaatgttctg ctgtttaact ttatgataga ctctactgca tcccgcaaaa ttgaactgaa
     4141 tgataccgta ttctcaaagg ataatatttc cgtttattat accgctcctt caacggattt
     4201 cggtatctgc aacaccgatt acctctgggc attgcaggtg actgtaccga agagcggcta
     4261 cagcggtcag aagatcgagt ggaaatgtat gggcgatgca aacggcgacg gcagctttgg
     4321 catagccgat attgtaacat tgcagaaatg gctcgctgct tcgtcagata ccgagctttc
     4381 ggacttgaag gcagttgata tatgcgagga cgatgtcatt gatgtatttg accttgtatc
     4441 tatgagaaag aagcttattg aagtgcatca gctcgataag cctgtaacat acggtatcga
     4501 agcacagtat gtacgtacca acggttatgt tgacggagct gaaagaatat attgagtctc
     4561 acaaggacaa atattatatg aagtcagccg aattcaatga tgctgttgag aaatacaacg
     4621 ataactggtt caattcccac aagcttatga tagttctgct tgaggaatcc agcggctctg
     4681 taagccacgg tgttacttcg gtaacaaaca gatccgtaac aatcaaccgt actgtaccgg
     4741 aagtcggtac gtgtgatatg gctgaatggc atatctttat tgaatatcca gaaactgcaa
     4801 atataagtga taacttcagc gttgaattta caaacactta tctcagataa tataaaaata
     4861 cagcaggtgc tcctgggtta cagggagtac ctgctgttta tacacttacc gttcagtaat
     4921 aaagctgttt acagtaagca agaaaagact tgattatgta tgaaaaaaat tgtagtatga
     4981 gtatatcagt atatttccca tgagatctga aaatatacaa aatctgatat gctaataaat
     5041 aataagggtg gagtagtttt atgaaaatga agaaagcaat tccttttata atgtctctgg
     5101 ctattgtcgg ttcatgctgt atgttcaata ataccgttaa tgacagatgc tcagcaatta
     5161 cagcagttac gatcgttgaa cagggaacat atgaggttga cgaaaacaca tcatttgagt
     5221 ataaagtaac agaaaatgat gatacatata tcggcaggta tacaggaact gccacagaag
     5281 ttgtgatacc ttccgagatc aacggcaaaa aagttacagg aatatcaggc aattcattct
     5341 ataatcgcgc tgatgtaact tcgatcacta tacctgacgg tatcacaaaa atctcaatgt
     5401 cggcttttga gaaatgtaca ggcttaacgt ccataacaat tcccgagggc gttgaagaga
     5461 tatcacacag ccttttcatg gattgcagca gcttaaaatc agttacactg cctgacagca
     5521 tcaagtacat tgattatgaa gcttttaaaa actgtactgc attggaatcc atcaatattc
     5581 ctgacggtct ggagtatgtt atgcccgatg cgtttacaaa taccaagtgg tacgacgatc
     5641 agcctgacgg aatgatatta ctcggaaaga cagtatataa atataaagga acaatgcctg
     5701 acaacacatc aatagttatt cctgacggta tcaagtgtat cggcggcgat gcttttttag
     5761 gctgtactgg tatgacctct gtaactatcc ctgatagtgt tggtttaatt gaaaacagag
     5821 ctttttcagg ctgcaccggt ctcacctctg tgactatccc tgactctgtt ttggaaatgg
     5881 gacatgatat ttttgaggac tgcacagggc tgacttctgt aaaacttcct gaaggtatca
     5941 aatattttgc ttacggaact ttaaaaggct gtacaggctt gacttctgta actcttccga
     6001 gcagtctgct tgcagttggt ctggaaactt ttgaaggctg tacaggtctg acatcaataa
     6061 caatccctga taatgttact gatattttgg ataatgcctt taaggactgt actgatatga
     6121 ctaaaatagt cattcccaaa aacgtatcat atatccatga aagtgtattt tcgggctgta
     6181 ctaacctgac tatctatgga tataagggtt cagaagctga aaaacatgct aaagataata
     6241 acatcaaatt cgttgcgctt gatgcggaaa caacacagca ggcaactaaa accacagcaa
     6301 aagctgcgac cacaacaaag gctgcaaccg ccaaaagcaa ctctcctcag acaggagaca
     6361 agggcagtgc gggaattatt acagcaggct ttgctgcatc agcattatca atcatttcat
     6421 tcaaaaagag aaagaagtaa aaatacagaa agtccctgca tttgcaggga cttattgttt
     6481 ttatatctgt ttatctgaca tatcttctgt taaatacaag aaatgctatc atcaataatg
     6541 ctgcgcccca tagagcctga acagctgtac cttcatttat tgcaagatac tgggggactc
     6601 ttactacaaa gaacgaattc attgtagata aaacaggaag atatttcatt tcggaactgt
     6661 actggagcag taaatttccc agtccaagga caagtgatac cattattgcc attgaaacga
     6721 tcatagaacg tgtaagtatt acaagtgcac tcgttataat aactatttca agtgttgata
     6781 aatagtccgg cagaaggagg ctcagagcct caccgatacc taagttttcg cttgatgaca
     6841 ttgctatggc tgctaatgaa aaaatggtgt tagccaataa caggatcact gaccatgtta
     6901 atatgcataa taattttgct gtaaggaaca tacccctttt tggagtactc agtaaactgg
     6961 ttcttaatgc tgatttttga tattcatatc caaagtacag tgcagttaat acagcatagc
     7021 ctgcctgacc aagataaaag ccttctatca gtttgctctt ggtcagcgta acgcctgttc
     7081 cgcccgtata tgaatcaagg gttattgcca ttacgggaac aaacacaagc aaaccaagca
     7141 ttactattac attccatttc tgatataaaa acttcttttg ttcacattta taatactgaa
     7201 gcagcattta atattctcct tgcaggtcga ttttgcggaa taaaatatag cctgcggaaa
     7261 cgaagaacag cgtccagcaa agcaggcata ttatattttt catcggcatt cccgaaagta
     7321 cactttcaga ggttgggata agtccgtttg aaagtgatac aggcaggtat ttgcacactt
     7381 caaatttctc tgcaagcata tttccaacat tatatgcctg tatgataagg aaaagaagcg
     7441 gcactaccgc tgttcggcac aggaatgcga tagcgtatga taatacagtc agaagcgtca
     7501 gtgataccgt tgagaacagt atgaatttcc ataccgtagc gttaaacaca agcggcttca
     7561 gtccctgatc accgaaagta aagtgtgtga ttgtaattgt aagtgtagtt gatataagag
     7621 aaatgaaaaa tgatatgatt gttactgcca gtgattttga tacaaaaaga tttcttttgc
     7681 ttccgaagga aagaagggag gttctcaggc tgtgcagctt gaattctgat gcaccgaata
     7741 aagcaccgag aactatcatc gggatagttg caaacattac tacatcaaag cccatgtatt
     7801 ctaaaggagg cataggctct gcaagctgat tggtttcggt tggtactgca tcgagtccga
     7861 cggaaagtgt ctgttttgca gatatatatg ccagcatact ttgtgctgct attacgagca
     7921 gtgtgactat tttgcatacc tttgtatagc agagcttcag cagctcgctg tacagattat
     7981 tcacaaagtt tttcatcagc agttcccctc atctgtaaga ttgaagaaca ggtcttcaag
     8041 tgaagagata tccttcatta cggtatcgag tgttcctttg gttacgatct ttccatgatt
     8101 gattataact acatcattgg taacagcttc gacctctgaa agcatatgag atgaaagcag
     8161 tacggtcttt ccgtcctttg cctgcttctt tacaaattct ctgaaccatc ttataccatt
     8221 cgggtcaagt ccgttggtag gttcatcaaa tataagaaac tgcggatcac ctataagtgc
     8281 agcggctatg ccaagtcgct gtccttcacc gagagaaagg cttcccacct gagaagatgc
     8341 cttatgggat attcctgtta tttccattac ctcatcaatt ctctttttag ggataccatt
     8401 gcttacggat atgatgcgaa gatgctgata tacagttctg tcgttaggcg agccgacgcc
     8461 atcgaatgat gcacctattt ttttcagcgg ttcattccat tttgcatagt tctgcccgcc
     8521 tataaatgct gttccgctgt ctgcgctgtc gagtccgaga agaattctga gagttgtgct
     8581 cttacccgca ccgtttggtc cgagaaaagc tgttatcctg cctttctgtg cttcaaaaga
     8641 aacatccttc aggatttcct tgtttccgta tttcttgttc acattgctga tcttgattga
     8701 ttgttccata taactcagct cctttctttt ttatattata ataattatag gcatgaaata
     8761 caacacgttt ttcataactt acaggtatac gaacatacct tgcatgatat tgattataaa
     8821 ttacattgac tttcattttt tcatatgcta taattgatgg tgcagttact ttaggaagtg
     8881 atgatttgaa aataaaactt attgtaaatc ctgaacacta tgaagctata tctgatgaac
     8941 taaacagact tggaatagaa ataagcgata atgcagatct tattctgacc gaacgaaatg
     9001 caagcatttc ctatctgata ggtaaaagaa atgaagagat atatcgtttg aaaacatctg
     9061 atatatctca tatagagagt ttcgctcacg aagttatagc atataccgat gaaggcgaat
     9121 tcagaataaa tgaacgattg aaaacacttt ccggacttct tgatcctgag atatttattc
     9181 gtataagtaa ttccgtaata atatcaaccg agcatataaa aagtataaag cccggcttta
     9241 ctcaaaagtt tatcgttacc atgcaaaacg gggcggttgt tgatgttaca aggacatact
     9301 actatttttt caaagaattt ttaggaatat gaggtcgtat atatgaaatt gttttattca
     9361 ttgatattac tgcttataat atcagttata tttgctgttg ttttaacatt tgtttatatt
     9421 atattatata ataattattt atctaaacgc gtaaaaaacg gtatcaagac aaaagacggc
     9481 ggcagacgtc atgttgagcc tttcaatttt tttctcatat gcttttttgt gattttgata
     9541 ttatcatgtc tggtgttatc ggtcaataac gataaaaaac taaatgcacc tgaatcgccg
     9601 ggatttgaaa tatgtgccga taacagctat gcggacagtt tttcatgcag cagtgagctg
     9661 cccggatata cacgttacga aaaggtcgtt gatgatataa gctgcgtgta ttatatcaac
     9721 aataataaaa acagtgcttt tccggcaatg tatctttata tcggatacaa aggaaaatac
     9781 agctttacat attattctga tgaaacaaaa aaagcgtctt cttccgatat ttccatatcg
     9841 ggtgaaaacg cagggtggta tgcactgaat gatatgcctg acagtgataa gctgtttctc
     9901 gatatcaaaa caggttccgc aagtaataca attgagataa agctataaac aaacagacac
     9961 atgaccgcga aggatcatgt gtctgttttg ttttatatgg ttaagaaaca agcatttgtt
    10021 ctttggcaag ttcataatac agaggaacag ttttgataag ttcatcgtga tttccttttc
    10081 cgactattct tccgtgttcc aatacgtaga tattatctgc attcattgtt gttgataatc
    10141 tgtgggctac cataatgatg gtttttgttc cgcgcagctc ttctacaaca tctttgatta
    10201 tgcgttcatt gatactgtcg agatttgatg taagctcatc gagtatgata atatcagtat
    10261 ccgacagtaa tgctcttgcc atagcgagtc tctgcttttc accgcctgaa agacctgtac
    10321 cgttttcatc aataacagaa tacaaacctt tcgagcgatt agttacgaga tatgaaagat
    10381 taactttttc aagagcttcc atgcactttt cttctgttac gttattattg ccgactttaa
    10441 ggttgtcgta tatagtaccg ctgagtaaag gtgcattctg ctcaatatac gtgatcttgc
    10501 ttctgagctc ttctcttgac atggtgtggt agtctttgcc gtatacacag atagttccgt
    10561 tgttaagctc ataaaatcgc tctataagct gaaggactgt actttttcct gcgcccgaag
    10621 gtccgacgat agccacacat tcaccattat ttatcgagaa cgatacatct ctcagaatta
    10681 cattttcgtc aaattcctct gtttcctgtc cgagaacgtg ctgaacataa gagaatgtta
    10741 cattgttgaa agtgatcgca tgatcgtctg tttctttttt attatcaatt atgatatcaa
    10801 actggtcttc aagaggcata ctgctgatct ccttgatgcg cttcaatgaa ccgacagaat
    10861 cagcgagtgt ggagatcgtt gagaagatct gctggaaagg ggatatagct atgtaaagca
    10921 gcaggacaaa tgatgtaaga tcacctacag acatctctcc ttttgataca cgccatccgc
    10981 cgatgccgat aactgccatt ccgcataact ggaggccgag gtttgagaca ggtgtcataa
    11041 atgcctgata ctttgcaagc ttcaggctga gagacttgac attttcagcc tcatcaactg
    11101 tttttttcaa ttcattcttg gtctcgtttg ttgaacgtat agttcttata ccacgcagtg
    11161 actgacctaa tttgccgctg agcttaccca tacctttctg agcttcataa cttgctttct
    11221 gaatgatgac ggacattaat gctatcagca caaaagaaac aaaaatagat attatagtta
    11281 caaggaacaa agtaaagtct tttaaaagca atcctattga tgctcctata gcaagaagca
    11341 atccgcttga caaagcaacg gttgactgaa tgatacctgc tcttaattta gaggtatcac
    11401 ctgtcagtct gcttatcaga tcacctgatg accatttgga ataattagct atcggtaatt
    11461 gaagaatatg gctgataagg tctttacgtg aacggaaaac agcctcttca cttattatct
    11521 gaaggagata atactgcagg gttgttataa ttgttgaacc taatataact ccgatgagta
    11581 taccgatctt tgaagaaata tttgtatctg tatttacatt gtttatgatg tcggatacaa
    11641 gatcaggctg tatcaacgta aagattgatg caataacacc gaggatcata acgatcagga
    11701 aatacttctt tttgtctgat accagtgcaa acagatcgcg tatctttaca tggatctctt
    11761 tgttattttc aatttcttca ggtttctttt cgttttcttc catttccatt cctttcggta
    11821 cttccgtttc gtcaggggtc tttataacct taacgaaaga gtctacttcc ttaggttcac
    11881 cggcaggtct tccgtagact tcgatccatg cgtgagctct gaacgggtcc atgcagtagc
    11941 ctgtacacca gcttactctt tttccctgca aagcaagaag tactgttgca gcaattgatc
    12001 ttttcagaca tctgtcctga ttacggcatt ttttgctgac atagcaaata gctcctcttg
    12061 cggtttcggc ttgcgttaaa gtggcaagag gctttttctt agtaatagct gtcagtattt
    12121 tttcaatcct tttaggtgaa aacagtatga gcggagcaga tatcagcaaa gcaaaagctg
    12181 ctaaaaattt gagtttgaat cctacatgga tatatttttc ctttgtaagc tgaagatcca
    12241 ttatgcaata cctgcctttt taagagaatc taaaaactca tttacgtcag tttcagcctg
    12301 agttctgtca atattgaaat tttctgcaac tgcatctgtt atttctgctg aatttttgcc
    12361 gccgctaagc tgctgtaata taaaagtgcc gacattattt gtctggaaat aaacaccgtg
    12421 tgtcttgtca aatacaatag caccgttttc ctgttctgtt atttttaatt caatttttct
    12481 tttgaataat cccataatta aacacctatt tctatatatt tatttacttg tctcagccat
    12541 ctttcaatat tgcatacacg cataaagaaa tcaacacgtt cgaaatttga tgatggcata
    12601 gaaagctctc ggtcaagaga ttcgtggttt attacgtcaa gttttgaaag aaagaattct
    12661 tttgttttgc ccatccattt ggctgcagca gcgcggtaat cattgtaaaa agcagatgaa
    12721 taatcacctt ttacgccgcg ggtgaatact tcaagcggaa ctataccttt aagcgcttca
    12781 tagagcatag gttttgtttt ctgaggatcg gtacagtatc ttgatggaag ggtcagtgcg
    12841 gtttttatga cttttgcatc aagaaacgga gcataccaac ctatttcatc acctgcaaca
    12901 tggactatct gtgaaaatat ttctttctgg aatagaatag actgtattct ctggtaatga
    12961 gacctgtcat cagataattc atagaactga ttggaaaata atgaattgat cttgctgtgg
    13021 gcagattctt ttgctgaatc cgtcagccat gaagggaata tcacatcttc agaccatgat
    13081 aattgacgtt tgtttttctt tttgctgcca aagccattgt ctattgattg ttttacttcg
    13141 tccttgagtg aggttttatt tgtaagatcc ttgatacatt tcaggaatga tcttcttgaa
    13201 agaatacaat acttaaaaat cagcggtata ctccttacaa cgccttcttc tcttatgatc
    13261 gaccacggta cagaagggat gtatgtaaag agttcatcgc ctccgattcc tatcatatgc
    13321 agatgtttgt ccttttcggg cagcttgcac agcatttctt ttacgtatcc ttcggtatcg
    13381 ccccatagaa gcggagaatc aggaacattg cttccaatgt attctttatc tactgaaaaa
    13441 cgtgaactgt tcttatcgat cgaaggcagt ttgttaagct caatgcgaag atcatcagcg
    13501 atatattgtg cccattttgt atcactgttt gctgattcat ctgattcagc atggaatatc
    13561 ataggctgtc ctgatatctt gtttacgaca taagcaatgc ttgccgaatc cacaccgcct
    13621 gatacgtcac aggacacaga gtcgaattga ctattctgat tgtatatgtt tgatattata
    13681 gtatcacgca gatcctttgt gaccttatca atgtcatgat caactttaaa agcattagtc
    13741 atttcgcact cagtaatatt gcctgagctt atctttaaaa tgcggaaagg atttattttt
    13801 gatatctcat cccagaaaga catattgctg aaaggctcaa atggcagtcc tgttacaaga
    13861 taagccgaaa tagaagattt agaaacctta aactgctttt tgtatgctat atcaaaagca
    13921 gagtcactta ttaatatctc actttcagtc ttgcagtatg atagagaagt atcaagaaaa
    13981 ggcccgaaaa tgatccaatc actgtctacc tcaagagcaa atacgcctgt aaggaatctg
    14041 tcctgaagat cggttattag tgattctttt tcgagcttta tcattttttc tatattattt
    14101 tcaatttctt tatcgtactt ttcgggataa tatagttttt tgtttccgag atcacggaaa
    14161 gtatagctgt ctttattaag gatcatcagc tttttattgc ccgaagtgcc gagagtgaat
    14221 tcttttatat tttttgattc caacggtcaa ccctctcctt ttgtatttta taattaaaca
    14281 aataaaatca tacattaata ctatatgatt ttatttgttt aatagtaaaa tgctgcaaat
    14341 ctcaacttga tttttaacag cattaattcc atgctaaatt aaagtatgtt ttagcaccga
    14401 aaatgtcacg aaatttaccg taccaaagac ccattgtgtt atccttgaat gaagcgacct
    14461 tttcaacgct tggcttattg tatgtcattt ttttacctct ttttttatat taagtgaaaa
    14521 cgcagcattt tctacaacac ttgtttctga aaatgctgca gatctcaact tatttttaaa
    14581 cagcattaac cgatcacggt gtagatgaat gccttaccat tcaacgtgaa tgaatgctct
    14641 accaccgaaa atgtcagtcc acttaccgaa ccaaacaccc attgtgttat ccttgaaaga
    14701 agcaaccttc tcaaagcttg gcttattgta tgtcattttt ttcacctctt tttttataaa
    14761 attgaaataa agcattttct gcatcacctg tttctgaaaa tgctgcagat tttaacttca
    14821 ttttaaacat cattagaaac cgatttcgat cttgatgatt gctctaccac cgaaaatgtc
    14881 attccattta ccgaaacaaa gacccattgt gctgttcttg aaagaagcaa ccttctcaaa
    14941 gcttggctta ttgtatgtca tgatatgtat cctcccttcc taaatgtgat ataaattacc
    15001 agaaaccttt atatcatcgt atttcttata catgaagtga aattcacgtt taagatgctt
    15061 ttattataaa tccgaatttt cagaaatttt tcagaaaata tcatttgtaa tgcgatatta
    15121 tttagctatt aaacaaataa aatcatacat taatgcaata tgattttatt tgtttaatag
    15181 taaaaatgct tgcttaccat gcaggactaa gagcaatgta tatctttccg ccgaagagat
    15241 ccttaaaatt gccgaaccaa aggcccattg ttttattctt gaaagaagca accttctcaa
    15301 agcttggctt attgtatgtc atttttttca cctctttttt tataaaattg aaatgaagca
    15361 ttttctgcaa cacttgtttc tgaaaatgct gcagatttta acttcatttt taaacatcat
    15421 tagaaaccga tttcgatctt gatgattgct ctaccaccga aaatgtcagt ccacttacct
    15481 gtccaaagac ccattgtgct gttcttgaaa gaagcaacct tctcaaagct tggcttattg
    15541 tatgtcatga tatgtatcct cccttcttaa atgtgatata aattaccaga aacctttata
    15601 tcatcgtatt tcttatacat gaggtgaacc tcacgtttaa gatgctttta ttataaatcc
    15661 gaattttcag aaatttttca gaaaatatca tttggggtaa agtttatata aaatgcacaa
    15721 acaatttatg aacaatttat taaacgtgct tgactgttga aagatcgaca aaagtaatgg
    15781 ttaaaataat aataataata atgtaatgaa gcattttctg cagcattgtt tccggaaatg
    15841 ctgcagaatc cgacttcatt ttaagtatta taaatcccaa ataaaaatac ccttagaacc
    15901 gaaaacgtct aatttcttac caaataaaat acccagtgta tctttcttga aagaagcaat
    15961 ttgttcaaat tttggcttgc tgtatgtcat agcatgtatc ctcctttctt taatgtgata
    16021 taaattaccg gaaacacttt atatcactga atttcttata catgaagcga acttcaggct
    16081 taagatgtct atattgtaaa taagaattat cagaaaaaaa tcaaaaaaat gaccttttag
    16141 agcaaatttg gctaaaatgc acaaacgttt ttcaggcatt ttgatggaaa tgagcgatta
    16201 atagaataat ttgtacaagt attgattaaa actaaaaata atgatataat aatacacata
    16261 gttaaaagct tttttattta taaataatga agctgtgcca cttgatattt ttcattgcaa
    16321 tagccttatg tatgaggtta ttgaatgtgc actaattaac tttttacata tttctaaaaa
    16381 tttatacaca catctactca cacatatact atttttatga tctgcttctg ataattcaac
    16441 aaaagttggg ggcttttttc agatcggatc attattgggg aaaaattgac atgtacaaaa
    16501 ttcttataat agatgacgat ccggctataa tacgtttaat aaaaaattct ttgtcaaatg
    16561 aatcatatga gttgcataca cgcaattctg tagaagatat caatttatgt gattttatgg
    16621 ggtttgatct catactgctt gatatggtaa tgccaaacag cggtattgat atctgcaaaa
    16681 tgatacgcaa tgaaataaag ataccgataa tttttatttc agctaaaagc tgtgaagata
    16741 atattatcga ctgtattact tctggcggcg atgattttat cgctaagccc ttcagtgtaa
    16801 aagaactgaa agcaagagta aaaatgcatc ttcgcaggga agaaagatat agcaagaaaa
    16861 agacgagcct tcgtgtcaat gacaggttta tagagctctc tgatcttaag gtcgtaataa
    16921 atgacagttc ttttttcctt actaaaaaag aatataatat aatcaagctt ctttccgata
    16981 actcaaaccg cgttttttcc tcggaagaaa tatatgactg cgtttaccct ttgagtaccg
    17041 atactcagat acgttcgatt tctgagtaca tctatcagat aagaaagaaa ttcaaaccgt
    17101 ttggtctgga tcctatcttt actgtatggg ggggcggtta ttgttggaaa aaataagctt
    17161 gaagtgtttg atcgtcaaaa cctttaaacg cattattttt caatgcatta catttttttt
    17221 cgcacttccc gttgggatat atattttatt ggcgttcttt tatatggtcc atatcagttt
    17281 tccgttatta agtttttgca atagcaattt ctggataatc gtgctcagcg gctggatcat
    17341 cataatttct ttaaattctt ttttgcttat tgagcgtatt tattcagata taaatggttt
    17401 gctgaaaaaa agctataacc gtttgaatgt aaatcctgac gatcgctgtg cttttcttat
    17461 atcggaaata gacgagataa ataactgttt ctttaagtat aaagagaagc tgtataataa
    17521 attcagtgac gaactgaatc agaaaaatga gtttctgttt ctgacttcta tttcttcaca
    17581 tgatcttaat tcgcttaata caataactca gggtaatatt gaattgcttg caggctcgga
    17641 tcttgatgcc caacagacag aatttctcga agatattaaa gcggcgtctg atgattcaca
    17701 gcaattcatt gagaacctta tacaatacct taacacattt tgtcttgaaa ggtataatat
    17761 gtctctgtgt tccgtatatg agctgttatc ttatatcaag caggataatg atataataac
    17821 agatgatcct gctgatataa ataaaaacgc tcttgcggta tatgataagg agctcaggat
    17881 atatgccgcc gaaactttaa gggcatttca ggtcgctata ggctgccttg agagatatac
    17941 caataattcg gaaagctgcc tgaaggtcga tatgtgtact gaaagagata tgtgcatttt
    18001 ctcaattaat aatatgggaa agccttttac tcaaaaagtt cttgctcagt atgatattac
    18061 ttcttccaga agatgtatat gtgataatgc aaacgaaagc agatttatca tacagctgat
    18121 gtatgtgaaa aaaattctgg aaatggaaaa agggtcaatg agacttgtta atatccacga
    18181 tcatccgatg atcgaacttt gccttccgat aatgtgatat tcaattaaag aaaaatggac
    18241 tgctgcggca gtcctttttg tttatgccaa agatgaggca aagtatattt gaaaagctgt
    18301 aaataaatat agcaaaaagc ggtcagataa ttacttgtta tgtcttgcaa tttatattgt
    18361 ttgatgttaa aatgttttca gaataatata aatcatttca tgataaagga gttgatatca
    18421 tgttaaggat agcaaatacc gaaaacggac aggtgcgagg tctgcccgca gccgacccaa
    18481 gaataacctc attcaagggc ataccctttg ccgctccgcc tgtgggggag aatcgctggc
    18541 gcgctccaca gcctgccgaa aactgggaag gcgtgcgcga ctgttttgag ttcgcaccca
    18601 tatccgttca ggacacaccg gggttaggcg acgatatata ctgtcgtgaa tggcacgttg
    18661 atcctgatat acctatgggc gaggactgtc tctatctcaa tgtatggact aatgcaaagt
    18721 ccgccaatga gcgcaagccc gtacttgtat ggttctttgg cggcgctttt cagtggggct
    18781 ataccgccga gatggaattt gacggtgaac gtctcgcaag gagagatata gtagtagtta
    18841 ctgtgaatta ccgactcggt gcacttggat ttctctgtca ccctcagcta actaaggaac
    18901 agcctgatgc accttgtaat ttcggctgtc tcgaccaaca ggcaggtcta aggtgggttc
    18961 ggcgcaatat agccaacttc ggcggtgatc ccgataatat aaccatagca ggacagtccg
    19021 cagggggcgg cagcgtaatg gcgcagatgg cttgtatgga caacgaaggc gatttcaaaa
    19081 aggttgttgt aatgagcgga atgttcggct caccatatac ggtaaatgat ttcttcctgc
    19141 cgcagagcgt tgaacaggca gagaaaaagg gggaaaggct ctttgagtat ctgggagtta
    19201 agacgcttga agaggcaaga aagcttgatg ccgactatat tcgcagcaag tattccgaac
    19261 ttcgcaataa tggtgagatg ttcttcacca tagtgcagga cggacatttc tgcacacagg
    19321 atccaatggc agctttcaga aacggtacac gtatccgcgt acctgttatg gccggaaata
    19381 caggcgatga gtttattgag tacattcatg cggcagatga agacgagttg tcagagaagg
    19441 ctgaggagta tttcggcggc agggctgagg agtttttttc atttcccgaa gcgagagtca
    19501 ggaatgattc aggttattcg ccgatctcat cgcctgagct tggggtaaag aaggctttcc
    19561 tcggtgataa tgggcagaat gcccctgaga actgctatta ctatcgtttt atttcagata
    19621 taccaggtga agatgctccc ggaacgttcc attcagttga tctatggttc tttttcgaga
    19681 ctctggcaaa atgcagcaga ccttatgagg gcagacatta tgatcttgcg agacagatgt
    19741 gtgattactg ggctaacttc ataaaaacag gcgatcctaa cggctttgat atcaacggca
    19801 ataagcttca cgaatggaag ccttatactg ataatgaacg caatgagatg ctttttacaa
    19861 gtgacggcgc aaaagcatcg accgagcaga gcggttttgt taggtttctg cttgacacaa
    19921 tgaaataagg aggtttattt atgagtaaga aacaggcatt caatccttat ctcccaagct
    19981 gggagtatat acccgacggt gagccctatg tgttcggcga ccgtgtatac gtttacggtt
    20041 ctcatgattt ctggaatggc tatgtgttct gcatggggga ttatgtgtgc tggtctgcac
    20101 cgatcgacga tcttggaaac tggcgttatg agggagttat ctatccaagg aacgccgacc
    20161 ccatgaacaa ggacggccat atgtgccttt atgctcctga tgttacagtt ggtcctgacg
    20221 gaagatacta cctctactat gtacttgaca aggtaggcgt tatgtccgtt gcagtttgtg
    20281 atgagccagc aggcaagtat gagttttacg gctatatcca ctatcctgac ggtacacgcc
    20341 tcggcgagag agaaggggac gagccgcagt tcgacccggg tgttatcacc gagggtgata
    20401 agacttatat gtacagcgga ttttgtcctg agggtgacaa gtccagaaca ggcgcaagag
    20461 tcgttacgct tgataaggat atgctgactg ttatcactga acctcagaca atagtgccgg
    20521 gtatatgtta cagcgaaggt actcagtatg aaggacacgc cttttttgag gcttcgtcca
    20581 tacgcaaggt gaacggtaaa tattacttca tatattcttc tgaggtcatg catgagctgt
    20641 gttatgctgt cagcgatgaa ccgctgggcg gcttcagata cggcggagtg ctggtcagca
    20701 acaccgacct gcatatagat acctacaagc ctgcggatat gcctgcaagc cgcggagcca
    20761 acaaccacgg cagtattatc gaaataaacg gcgagtggta tatcttctat cacagacata
    20821 ccaacggcac atggttctca aggcagggct gtgcagaaaa gctgactctc aatgcagacg
    20881 gcagcttcga tcaggctgag ataacttcct gcggtctcaa cggcggtcct ttggagggca
    20941 ggggcgaata tcctgcttat atcgcctgca atatcttcgg caggaacccc gagctctata
    21001 tcggagacct caatgcccca cgcatagtgc aggacggcaa agacggtgat gaggagatag
    21061 gatatatctc aaatatcaaa gaagggacta atataggctt caaatacttc gactgcaagg
    21121 gtatcactaa ggtgagcatt actaccagag gctattgcgg cggtactttt gctgttaaga
    21181 ctgcttggga cggtgaagaa cttggagaga tagaagtgga gaacagcaac gtatggaaga
    21241 aatccactgc tgatatcagg atacccgacg gcgtgaatgc tatatggttc accttcaagg
    21301 gcacaggtaa tcccagtttc ggttcgttca caatggtgtg atattgcata aatgaaggta
    21361 tgattatggt gaagatttat taaaaaatag ggtaaatttt attaaaaaag cgttacaaag
    21421 cggttaaatt ttgggctttt ctaaccattt tttgcgaaaa atatatgaat ttttttgcct
    21481 gtttatcttt ttttgccttt attacagata tttattgaca agttgtatat aatatggtaa
    21541 aattaacaaa gacaccgaag aggtgcaaca tcaaattcgg tacaaccgta aaacttgccg
    21601 aacgacaatt atgtaggtat gtttcgtgcg gcgattaacc aggaggtaat agtaatgaaa
    21661 aaaagaagaa tcttagcaac aattatgaca gcagcaatgt tcgctactac tcttgtaggc
    21721 tgcggcagtg acaacaacag cagttccggt ggttcaagca gttcaggcaa tggcggcggt
    21781 gactccggaa aggttcagga gatcacatgg atgttctggg acgaccttaa tgctaccgag
    21841 gatcttatct ctcttggcta taaggagact attgagagat tcaataatga tttcaagggc
    21901 aagtatcatg taactcctat tacaacaaac cttgaagaat attacaacaa gctcaatgct
    21961 cttgttgcag caggcgatac acctgacgta ttcatcgtaa gccctggtcc gcagctcaca
    22021 gactatgttg agccgggcgt tgcagctccg cttgatgatt atctcaacaa ggacggctgg
    22081 aaggatacat tcacaagtga tgctgtattc acacagcaga catacgatgg caagatatat
    22141 gctgttccgc ttaacacagc agctgcttgc tgcttctaca atacagagat gtttgagaag
    22201 gcaggcgcta aggtacctac caactgggac gaaatgatgg aagcatgcga gaagctcaag
    22261 gctgcaaatt atactcctgt aactatctcc gcaggtactg catggtgcct ctcaatggta
    22321 gcaggttatc tctgtgaggc agagggcgta gacctttcaa agcttgctga cggttctgct
    22381 tcatgggaag acggtaagct cgagagcgct tgcaataagc tccttgatct ttcaaaatac
    22441 ttccagagaa cagcagctgg tgatacaaac gatgttgcta cagctaactt ctacaacgaa
    22501 gaggctgcta tccttatcca gggttcatgg gctatcgcac agataaacgg ttctaaccct
    22561 gactttgagt caaagtgcgg cgtattccag ttcccgggcg ttgacagaat catcgctaag
    22621 tctgactcac tctgcatgag ctcaacaaca aagaatcctg agggcgcagc tgctcttatc
    22681 aagtacttca cagatgacac agctcagaag tacacagctg aaaaaggcgg taagatccct
    22741 gtaacaaagg ttcagtacga tgtatctgca gctcctaagc agctcggtta tgttatggac
    22801 gtattcggca gcgcaaaggg tacattcggc ttctacaacg agtcaatgcc tactactgag
    22861 acaggtgctc acttcgatga cacaatggtt tctgtattcc ttggtgacat gaagcctgct
    22921 gaggctgcaa aggacatgga ggaattctac aaggctaatt gcagaaagta atctcttact
    22981 tattttgaaa aactataggg gcgtacccta cgcccctata ttattttaac attttcacta
    23041 tattgatctt ctgaaaggag tggttacagg atggacaaat tgcttaggaa caagaaggca
    23101 ctcgctgttt tcatgcttcc tgctttcatt ttgttcacat tggtgctttt tataccgatc
    23161 gttcagtcgg tatattattc attctgtgat tataaaggct ttactgcccc tgttttcatc
    23221 ggaattgata attacaaggc gctgctttcc gataaaacat tcggcatagc tctcaaaaac
    23281 tcaatatttt tcctgatttt ctcatgtgtg tcacagctta tcgttggtct tttcttcgca
    23341 gcactgctga caaacatcaa ggtaggacga aatgcattca agaacataat atatctccca
    23401 tgcgtacttt catctgctgc cctcggtctt atgtggatgt tcatattcag ccctaagctc
    23461 ggtatcaacc agcttcttga aaaatggggc gttgaggaac cgcctctctg gcttatggat
    23521 acaaagggac atattatcct tcctatgtgg ataatcgctt ttgttgctct ctggcagtat
    23581 gtaggtcagt cgatgatgct ttatatggct cagatatcag gtataagcaa gtcacttatg
    23641 gaggcaagct atatcgacgg ctgtacaaaa gcaaagacat tcagatacat aacacttccg
    23701 ctgataaagc cgatgatagc tacagctatg tcactcaatg ccataggctc actgaagttc
    23761 ttcgacctta tctataatat gacaaagggc ggaccgaacc acagtacaga ggttcttgca
    23821 actcacctct atgagcaggg cttcaagtat ttcaaatacg gctatgcaag tgcaataggc
    23881 gtagtactgc ttgtactctg tctgatagta acactgttta tcaataaggt cgtaaagacc
    23941 gagcagtacg agatgtaagg aggtcgggtc aaatgagtac aaaatcttta gtagccgaac
    24001 tgactcctgc atctaagaat aagaaaaaga tcacgcctat acaggtattg atatatgtct
    24061 ttcttattct tatatctata acatacatct tccccctact ctgggtgttc aatgtatcct
    24121 tcaaaaccaa taaggagata tttaccgctc cttttgctct tccaaaggac gtaacatttg
    24181 ataactattc ctttgcgtgg acagcaggac gtcttggcgt agcaacactt aactcgttca
    24241 tcg
//
