LOCUS       NZ_KI912489.1          22943 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_KI912489.1 Ruminococcus flavefaciens ATCC 19208
            L870DRAFT_scaffold00001.1, whole genome shotgun sequence.
ACCESSION   NZ_KI912489
VERSION     NZ_KI912489.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:56:51
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 174961
            Orig. end    :: 197904
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22943
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[184961:187904]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12943
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..22943
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22943
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="2"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             664..2763
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     124.9; E-value: 4.8e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_155"
                     /transl_table=11
                     /translation="MLKLGEWIAKHRALILVVSVVMLIPAAIGYVKTRVNYDILSYLPK
                     NINTMVGQDILKEQFGQGGFSLVMVEGMSDKDVAATADKIAAVDHVSNVVCYQSMTGCT
                     IPKEILPADIYDFFNKGDTTMMAVFFDDTTSADATLNAVETMRSITSKQCFISGMSAMT
                     LDMKNITQNETLIYALIAVILTSIVLMITMDSFLIPVFFMLSIGFAVVWNLGSNIFLGE
                     ISFITQALAMVLQLGVTMDYSIFLWHSYKEQQKFYPDSRQEAMAHAISATITSVVGSSF
                     TTVAGFLAMCFMTFTLGLDLGIVMAKGVVCGVIACVTVLPSMILIFDKAIAKTSHKDFL
                     PGFKRTSSFIVKHSWVFLTGAIVLLIPAVFGNSNYGVYYKLDSTLPKTLDSVIANTKLA
                     EEYNMNSTHILMVRSDMSAKDANKMMNKIESVDGVQFTLGFNSLVGSAIPEEAVPKELR
                     SVLKSDEWQLILIGSEYEVASDDVNEQVGTINKIVQKYDPNGMLIGEAPATKDLITITD
                     RDFKIVNFLSIAAIFLIIAFTFRSISLPVILVSVIELAIMINLGLAYYTGSKLSFIAPI
                     VIGTIQLGATVDYAILMTTRYRTERSSGKDKKESIGIALSTSIKSVITSALGFFSATVG
                     VALYSDIGLISELCMLLARGALISMVIVITVLPSMFMVFDKVICKTSAGLLPKKNKFEY
                     RYKNA"
     PFAM_domain     1063..1665
                     /aSDomain="MMPL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03176.17"
                     /description="MMPL family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_155_0045"
                     /evalue="2.30E-23"
                     /label="ctg1_155"
                     /locus_tag="ctg1_155"
                     /protein_end="334"
                     /protein_start="133"
                     /score="82.7"
                     /tool="antismash"
                     /translation="TSADATLNAVETMRSITSKQCFISGMSAMTLDMKNITQNETLIYA
                     LIAVILTSIVLMITMDSFLIPVFFMLSIGFAVVWNLGSNIFLGEISFITQALAMVLQLG
                     VTMDYSIFLWHSYKEQQKFYPDSRQEAMAHAISATITSVVGSSFTTVAGFLAMCFMTFT
                     LGLDLGIVMAKGVVCGVIACVTVLPSMILIFDKAIAKT"
     PFAM_domain     2068..2682
                     /aSDomain="MMPL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03176.17"
                     /description="MMPL family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_155_0046"
                     /evalue="1.60E-28"
                     /label="ctg1_155"
                     /locus_tag="ctg1_155"
                     /protein_end="673"
                     /protein_start="468"
                     /score="99.7"
                     /tool="antismash"
                     /translation="ILIGSEYEVASDDVNEQVGTINKIVQKYDPNGMLIGEAPATKDLI
                     TITDRDFKIVNFLSIAAIFLIIAFTFRSISLPVILVSVIELAIMINLGLAYYTGSKLSF
                     IAPIVIGTIQLGATVDYAILMTTRYRTERSSGKDKKESIGIALSTSIKSVITSALGFFS
                     ATVGVALYSDIGLISELCMLLARGALISMVIVITVLPSMFMV"
     CDS             2799..5516
                     /locus_tag="ctg1_156"
                     /transl_table=11
                     /translation="MKKVSKVMAALIATAVSAGATGSIAYAKSSGKVQETAEKTKETDS
                     AEASSRKDNGENAYKDETVYVLCNSDSSIKNVVVSDWLKNAPALGSISDISELSDIVNV
                     KGDEEFSLNGENISWQADGSDIYYKGNTDKDLPVDVDIEYTLDGKKVTPESIKGKSGHL
                     VIRWTYKNNQKVTKTVNGKTKELYVPFMAASAAVLSTDNYLNVEVKNGKVISDGDRLIV
                     VGMAFPGLGESLDLSKIEGMNIEIPDSFEISADVTNFEMNTSVTVVSNEIFSQLDIDNA
                     ADLGDLKDKLKELSDGAEKLTDGTAALYDGIKKLNGGAGELSSGIDKLLSGSLELKNGA
                     SELDSGAKKLADGAKTLSDSTGTFEAGLGSAKDGSSKLVAGIEQLSGGASQLSDGAGSA
                     KAGSAALVDGFGKVSAGADALSSGLKDAKDGSDALTAGFTKVNEGAAALKDGAGTLTSG
                     VGAIKDGSTQVKDGSAQLAAGASALNDGAAKLSESAGQMSAGITSAKSGADSLAEGIAS
                     AKTGADQLSGGASALSEGAAKLSDGIAAAGSSLDTTIAANEQALAALQALYQQSPSQEL
                     AVAIGTLQQTIEGQKQISASMAESGALGAGAASVKNGAAQLNGGIGQLSTGLEAAKSGS
                     ETLKGGLAALDDGGKALAAGASTLSGSTAQLSKGASDLSTGAAALDSGIGTLAGGSSQL
                     IGGLDSLIDGIGQLSSGNASLNAGLGKLSTGAVDLSGGIGQLSDGASALDSGLAQLSQG
                     TLTLNGGFGQLSTGAVTLDDGLAQLFGGSKQLSGGAKTLYDSIKLLSTGAAKLSSGSGE
                     LYSGVDKLKIGSKTLSDGVSQLESGAKELNDGMIKFNNEGISVLTGAVNENLPDIIENF
                     KALRDASREYNSFSGISDKMDGSVKFIYLVDGTK"
     aSDomain        3654..3731
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_156_0005"
                     /evalue="3.40E-04"
                     /identifier="TIGR03057"
                     /label="ctg1_156"
                     /locus_tag="ctg1_156"
                     /protein_end="311"
                     /protein_start="285"
                     /score="18.7"
                     /tool="antismash"
                     /translation="DLKDKLKELSDGAEKLTDGTAALYDG"
     aSDomain        3720..3794
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_156_0006"
                     /evalue="2.40E-04"
                     /identifier="TIGR03057"
                     /label="ctg1_156"
                     /locus_tag="ctg1_156"
                     /protein_end="332"
                     /protein_start="307"
                     /score="19.2"
                     /tool="antismash"
                     /translation="LYDGIKKLNGGAGELSSGIDKLLSG"
     aSDomain        3801..3875
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_156_0007"
                     /evalue="5.60E-06"
                     /identifier="TIGR03057"
                     /label="ctg1_156"
                     /locus_tag="ctg1_156"
                     /protein_end="359"
                     /protein_start="334"
                     /score="24.4"
                     /tool="antismash"
                     /translation="ELKNGASELDSGAKKLADGAKTLSD"
     aSDomain        3921..4004
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_156_0008"
                     /evalue="4.60E-05"
                     /identifier="TIGR03057"
                     /label="ctg1_156"
                     /locus_tag="ctg1_156"
                     /protein_end="402"
                     /protein_start="374"
                     /score="21.5"
                     /tool="antismash"
                     /translation="SSKLVAGIEQLSGGASQLSDGAGSAKAG"
     aSDomain        4194..4274
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_156_0009"
                     /evalue="5.60E-05"
                     /identifier="TIGR03057"
                     /label="ctg1_156"
                     /locus_tag="ctg1_156"
                     /protein_end="492"
                     /protein_start="465"
                     /score="21.2"
                     /tool="antismash"
                     /translation="STQVKDGSAQLAAGASALNDGAAKLSE"
     aSDomain        4983..5057
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_156_0010"
                     /evalue="2.80E-04"
                     /identifier="TIGR03057"
                     /label="ctg1_156"
                     /locus_tag="ctg1_156"
                     /protein_end="753"
                     /protein_start="728"
                     /score="19.0"
                     /tool="antismash"
                     /translation="LSGGIGQLSDGASALDSGLAQLSQG"
     aSDomain        5106..5180
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_156_0011"
                     /evalue="3.50E-04"
                     /identifier="TIGR03057"
                     /label="ctg1_156"
                     /locus_tag="ctg1_156"
                     /protein_end="794"
                     /protein_start="769"
                     /score="18.7"
                     /tool="antismash"
                     /translation="TLDDGLAQLFGGSKQLSGGAKTLYD"
     aSDomain        5193..5261
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_156_0012"
                     /evalue="5.20E-05"
                     /identifier="TIGR03057"
                     /label="ctg1_156"
                     /locus_tag="ctg1_156"
                     /protein_end="821"
                     /protein_start="798"
                     /score="21.3"
                     /tool="antismash"
                     /translation="LSTGAAKLSSGSGELYSGVDKLK"
     aSDomain        5250..5330
                     /aSDomain="TIGR03057"
                     /aSTool="tigrfam"
                     /description="xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad
                     repeats"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_156_0013"
                     /evalue="4.70E-06"
                     /identifier="TIGR03057"
                     /label="ctg1_156"
                     /locus_tag="ctg1_156"
                     /protein_end="844"
                     /protein_start="817"
                     /score="24.6"
                     /tool="antismash"
                     /translation="DKLKIGSKTLSDGVSQLESGAKELNDG"
     CDS             complement(5824..6321)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 70.2;
                     E-value: 3.4e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_157"
                     /transl_table=11
                     /translation="MRLRPYIPSHDFDAIKDWITDERTHAMWSAKHAPYPLEKNAFDQF
                     LADMYTKHGDCPFVATTDDGKVVGFLCCGINTESNEAMLAFVIVDPAQRGKGYGREMIQ
                     LAAKYCTEILKADAVQLNVFTVNEKARKCYESAGFTERHTTPDAFAYGDEMWGRCNMVF
                     KK"
     PFAM_domain     complement(5905..6198)
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_157_0047"
                     /evalue="3.80E-16"
                     /label="ctg1_157"
                     /locus_tag="ctg1_157"
                     /protein_end="139"
                     /protein_start="41"
                     /score="59.5"
                     /tool="antismash"
                     /translation="FDQFLADMYTKHGDCPFVATTDDGKVVGFLCCGINTESNEAMLAF
                     VIVDPAQRGKGYGREMIQLAAKYCTEILKADAVQLNVFTVNEKARKCYESAGF"
     CDS             complement(6491..9130)
                     /gene_functions="other (smcogs) SMCOG1037:heavy metal
                     translocating P-type ATPase (Score: 595.1; E-value:
                     3.4e-180)"
                     /gene_kind="other"
                     /locus_tag="ctg1_158"
                     /transl_table=11
                     /translation="MKHYLESTDSVLKEVDSSVSGLTKEEAAKRLETNGKNKLDEPPKP
                     TMLARFIEQFKNPMIIVLIAAAVISAITGIISEGKLDADVFIILFVVIANAVLGVYQEN
                     KAESAIEALQAMSAAQSKVFRSGELVVIPSSELVPGDVIALEAGDNVPADCRILEAAAL
                     KAEESALTGESVPSDKDSEVLTGEEVPLGDRKNMLYMGSSIAYGRAEAVVVATGMKTEM
                     GKIAGAIANADDDETPLQKSLDQLSKILSIAVLVICIIILGLNIVRMLIADGSITLPKF
                     LESFMIAVSLAVAAIPEGLAAVVTVVLSIGVTNMSKRGAIIRRLTAVEALGCAQVICSD
                     KTGTLTQNKMTVVQENTDDKEFLAKAMALCCDAQLNSDDTVAGEPTEAALVAYAHRCGL
                     KKYELEAATPRVAEAPFDSMRKMMSTVHKTDKGYIQYTKGAPDEVLKNCTHMFKEGGVR
                     IMTESDRLEILRRNKEMADNALRVLLAAYREYDELPADTAPEALEHDLIYIGMTGMIDP
                     VRPEVKDAIGLCRTAGIRPVMITGDHRDTAVAIAKELGILEKGQQALTGAELSKIPDEE
                     FNEHVGDYSVYARVQPEHKVRIVNAWRKKGMTTAMTGDGVNDAPSIKSADIGVGMGITG
                     TDVTKNVADMVLTDDNFATIVGAVEEGRRIYDNIRKAIQFLLSSNLSEVLCILIATIGL
                     GSLTDGSFVLFNPVHLLWINLISDCFPAIALGMEPAENGIMSRKPRSSNSHIFSDGLGI
                     NLLWQGTVIAILTLISYVIGFNSEGHEAGMTMAFITLCVCEMLHAWNMRSLKDSIFTMK
                     KHNKVLIGAIALSAVLTIPILFIPSLRDMFSLSELFAENYLCAFIMGAFIVPVVEAVKY
                     FQRKADNK"
     PFAM_domain     complement(6515..7024)
                     /aSDomain="Cation_ATPase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00689.23"
                     /description="Cation transporting ATPase, C-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_158_0051"
                     /evalue="2.00E-47"
                     /label="ctg1_158"
                     /locus_tag="ctg1_158"
                     /protein_end="872"
                     /protein_start="702"
                     /score="161.4"
                     /tool="antismash"
                     /translation="VLFNPVHLLWINLISDCFPAIALGMEPAENGIMSRKPRSSNSHIF
                     SDGLGINLLWQGTVIAILTLISYVIGFNSEGHEAGMTMAFITLCVCEMLHAWNMRSLKD
                     SIFTMKKHNKVLIGAIALSAVLTIPILFIPSLRDMFSLSELFAENYLCAFIMGAFIVPV
                     VEAVKYF"
     aSDomain        complement(7055..7378)
                     /aSDomain="TIGR01494"
                     /aSTool="tigrfam"
                     /description="ATPase_P-type: HAD ATPase, P-type, family IC"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_158_0016"
                     /evalue="1.40E-31"
                     /identifier="TIGR01494"
                     /label="ctg1_158"
                     /locus_tag="ctg1_158"
                     /protein_end="692"
                     /protein_start="584"
                     /score="107.5"
                     /tool="antismash"
                     /translation="SVYARVQPEHKVRIVNAWRKKGMTTAMTGDGVNDAPSIKSADIGV
                     GMGITGTDVTKNVADMVLTDDNFATIVGAVEEGRRIYDNIRKAIQFLLSSNLSEVLCIL
                     IATI"
     PFAM_domain     complement(7778..8023)
                     /aSDomain="Cation_ATPase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13246.8"
                     /description="Cation transport ATPase (P-type)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_158_0050"
                     /evalue="3.30E-22"
                     /label="ctg1_158"
                     /locus_tag="ctg1_158"
                     /protein_end="451"
                     /protein_start="369"
                     /score="78.4"
                     /tool="antismash"
                     /translation="CCDAQLNSDDTVAGEPTEAALVAYAHRCGLKKYELEAATPRVAEA
                     PFDSMRKMMSTVHKTDKGYIQYTKGAPDEVLKNCTHM"
     aSDomain        complement(8048..8485)
                     /aSDomain="TIGR01494"
                     /aSTool="tigrfam"
                     /description="ATPase_P-type: HAD ATPase, P-type, family IC"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_158_0015"
                     /evalue="7.90E-25"
                     /identifier="TIGR01494"
                     /label="ctg1_158"
                     /locus_tag="ctg1_158"
                     /protein_end="361"
                     /protein_start="215"
                     /score="85.2"
                     /tool="antismash"
                     /translation="TGMKTEMGKIAGAIANADDDETPLQKSLDQLSKILSIAVLVICII
                     ILGLNIVRMLIADGSITLPKFLESFMIAVSLAVAAIPEGLAAVVTVVLSIGVTNMSKRG
                     AIIRRLTAVEALGCAQVICSDKTGTLTQNKMTVVQENTDDKE"
     PFAM_domain     complement(8177..8785)
                     /aSDomain="E1-E2_ATPase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00122.22"
                     /description="E1-E2 ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_158_0049"
                     /evalue="4.30E-53"
                     /label="ctg1_158"
                     /locus_tag="ctg1_158"
                     /protein_end="318"
                     /protein_start="115"
                     /score="179.6"
                     /tool="antismash"
                     /translation="MSAAQSKVFRSGELVVIPSSELVPGDVIALEAGDNVPADCRILEA
                     AALKAEESALTGESVPSDKDSEVLTGEEVPLGDRKNMLYMGSSIAYGRAEAVVVATGMK
                     TEMGKIAGAIANADDDETPLQKSLDQLSKILSIAVLVICIIILGLNIVRMLIADGSITL
                     PKFLESFMIAVSLAVAAIPEGLAAVVTVVLSIGVTNMSKR"
     aSDomain        complement(8576..8872)
                     /aSDomain="TIGR01494"
                     /aSTool="tigrfam"
                     /description="ATPase_P-type: HAD ATPase, P-type, family IC"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_158_0014"
                     /evalue="3.00E-18"
                     /identifier="TIGR01494"
                     /label="ctg1_158"
                     /locus_tag="ctg1_158"
                     /protein_end="185"
                     /protein_start="86"
                     /score="63.5"
                     /tool="antismash"
                     /translation="IILFVVIANAVLGVYQENKAESAIEALQAMSAAQSKVFRSGELVV
                     IPSSELVPGDVIALEAGDNVPADCRILEAAALKAEESALTGESVPSDKDSEVLT"
     PFAM_domain     complement(8921..9115)
                     /aSDomain="Cation_ATPase_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00690.28"
                     /description="Cation transporter/ATPase, N-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_158_0048"
                     /evalue="8.60E-20"
                     /label="ctg1_158"
                     /locus_tag="ctg1_158"
                     /protein_end="70"
                     /protein_start="5"
                     /score="70.3"
                     /tool="antismash"
                     /translation="ESTDSVLKEVDSSVSGLTKEEAAKRLETNGKNKLDEPPKPTMLAR
                     FIEQFKNPMIIVLIAAAVIS"
     CDS             complement(10001..10156)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_159"
                     /sec_met_domain="TIGR04223 (E-value: 4.7e-08, bitscore:
                     28.3, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFSCDSVKAKIMKTIVTKSIKAAEQNVNSACIYLCNQPTPPKDL
                     KKFRKF"
     aSDomain        complement(10016..10099)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_159_0017"
                     /evalue="3.20E-07"
                     /identifier="TIGR04223"
                     /label="ctg1_159"
                     /locus_tag="ctg1_159"
                     /protein_end="47"
                     /protein_start="19"
                     /score="28.3"
                     /tool="antismash"
                     /translation="SIKAAEQNVNSACIYLCNQPTPPKDLKK"
     CDS             complement(10300..11628)
                     /locus_tag="ctg1_160"
                     /transl_table=11
                     /translation="MMFLIELATLIAFYVFTYVLYEKIYPLKKINIFFRILFIIAAALI
                     MAYIKTFKINILNFSFSFLSVILFNVIFFKPTSKSFLIYDAIIFVIMLIVEMITAFIIA
                     LIINVPVERITDKPYSFAATALMNWIIMLALAKVFVNINSEKGMNNVRTQEVIMFVGLI
                     IGEIILFNFLTDIISESKNRYEVVIILLIFLLLDLYLTYLINRMSKAYKTEKKLELLTQ
                     QSTLQLNAYNKLNEKYIASRKVIHDVRKHLASLEGLITANKADEAGKYRDMLNYELNKL
                     MPRFECDNSILTVVINNKLEAADNMKVDFRVNAEFTEINFISNLDITAIFSNLLDNAFE
                     ACAELPEEKRHVTLSIARRNYFVFIYVENTFAEVNQDVKKVFRSTKKGHQGIGLSNIKS
                     ACEKYNGNFNAHTENDMFITEILIPIPETSDSKDMLQKVHTNI"
     PFAM_domain     complement(10357..10662)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_160_0052"
                     /evalue="2.10E-25"
                     /label="ctg1_160"
                     /locus_tag="ctg1_160"
                     /protein_end="424"
                     /protein_start="322"
                     /score="88.7"
                     /tool="antismash"
                     /translation="SNLDITAIFSNLLDNAFEACAELPEEKRHVTLSIARRNYFVFIYV
                     ENTFAEVNQDVKKVFRSTKKGHQGIGLSNIKSACEKYNGNFNAHTENDMFITEILIP"
     CDS             complement(11637..12362)
                     /locus_tag="ctg1_161"
                     /transl_table=11
                     /translation="MINIAICDDDNDMIQALKSAISSYSKTHAIEFEVHSFQSGEKLLD
                     CKLDFDLIFLDIEMGGMDGLKTAQLYRQIDRRARIVYVTNHSELALQSYAVHPFDFVVK
                     PFESSRIFSVLGELTKYLSENSAKDTVIQLKGEDGPLLLNLKNIYVFEYTGNRRITVYT
                     ESEKYQIKGSLSDVFSIINSESFVSPHKSFIVNMEHIDKLNNFTLYTTNGIEVPVAQKK
                     LKEFHNEFSRFIKNYIRQG"
     PFAM_domain     complement(11679..11942)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_161_0054"
                     /evalue="2.60E-17"
                     /label="ctg1_161"
                     /locus_tag="ctg1_161"
                     /protein_end="228"
                     /protein_start="140"
                     /score="62.9"
                     /tool="antismash"
                     /translation="LLLNLKNIYVFEYTGNRRITVYTESEKYQIKGSLSDVFSIINSES
                     FVSPHKSFIVNMEHIDKLNNFTLYTTNGIEVPVAQKKLKEFHN"
     PFAM_domain     complement(12024..12353)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_161_0053"
                     /evalue="3.10E-16"
                     /label="ctg1_161"
                     /locus_tag="ctg1_161"
                     /protein_end="113"
                     /protein_start="3"
                     /score="59.6"
                     /tool="antismash"
                     /translation="IAICDDDNDMIQALKSAISSYSKTHAIEFEVHSFQSGEKLLDCKL
                     DFDLIFLDIEMGGMDGLKTAQLYRQIDRRARIVYVTNHSELALQSYAVHPFDFVVKPFE
                     SSRIFS"
     CDS             complement(12359..12943)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_162"
                     /sec_met_domain="AgrB (E-value: 3.6e-35, bitscore: 116.3,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRILDAIMEKLLSSGYAKEEDAEIVRYGLELTIMTTLTTAFMII
                     TAILMKSFIAVIVFLALYMPMRNCCGGYHSASRLGCFMISVVMLAAVIAASKLIHDPER
                     LYVSAAFLFSGIVVILFAAPTETPTKPFDDTERRVFRRRSLMITALGTALAVISAVFRL
                     YILTLSLSLAVFVTAFLLVAGRISNRKGVEK"
     PFAM_domain     complement(12401..12925)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_162_0055"
                     /evalue="6.40E-34"
                     /label="ctg1_162"
                     /locus_tag="ctg1_162"
                     /protein_end="181"
                     /protein_start="6"
                     /score="117.0"
                     /tool="antismash"
                     /translation="AIMEKLLSSGYAKEEDAEIVRYGLELTIMTTLTTAFMIITAILMK
                     SFIAVIVFLALYMPMRNCCGGYHSASRLGCFMISVVMLAAVIAASKLIHDPERLYVSAA
                     FLFSGIVVILFAAPTETPTKPFDDTERRVFRRRSLMITALGTALAVISAVFRLYILTLS
                     LSLAVFVTAFLL"
     CDS             13170..16073
                     /locus_tag="ctg1_163"
                     /transl_table=11
                     /translation="MKIKGFISLLAALTVITSSVAAVPFSASAEVVSETEIAAEYDFSG
                     VSSTVEKDGVSYSIFKGYAAVHYVNDENIEEFTVPETINDVPVVGIEWGAFRNCKNIKK
                     LTLTKNVSVINWGDIAEFSMEEIAVTEDNESFTVVDGVLYSKDMKTVVAFPPSNSAAEV
                     KIADEAENIAPYAFVSCQKLTKIEVSNNVGEIGEGAFVGCTSLTSINIPDGVKAINTYT
                     FAGTKALKGVRIPGSVDYMYNDAFKDSGAIENEGGIHYVDKWAVGADNDIERADIRMGT
                     VGTMEGLFVSKNKLRVVTVPDSVIHLGSYLVFGLYTPVELVEFHCPAIPARVLGCLSVK
                     EVWIYDRNCKIEDDASSLPTYWREPKEAPEEEETTEENDYIIRHTRVTASSSSGANSIA
                     KVINTSLTEIDEEDDDAGEITTITHSVNTSSTDSKFKEKVEAYMEKYREKLSQNTEDNS
                     GVAVAQPVEKVYKSPIKIGNPAKYDTIIRGFERSTAEEYALKYRRVFDTFEPASTVVGP
                     ESVTDHENSDIEYRVYGNSYAIASLRDGYHPDGSNRKKEITIAEEINGVPVTAYRLGGG
                     DADIIHLPKTVSTILYSVDVATSYNCSYDIDKDNPYLTSVDGIIYSKDMTKLIKVPSRY
                     EGKKIVVPDGVKSIEDFAMLNLRNVESIELPDSLEEIKYGAFLDATKLKSINLPENLDF
                     IGDRAFNYCISLEDIKIPESVKGIGLYAFYDVPAVNYEGGLGYLDNWLVEAEADDKPNM
                     IVPKEGITGMARVCAKDSLVIPKSVTKMGWEVLGLYNSITRADVYSHVIDYDAFKNARY
                     LKDIYIYDPECEICAGDQTIPAKYIDTDNRVIKKFDELVPDIKSLNARTYAYELKAGDG
                     EKLGDTVIHGYKGSTAEAYAQMYGIKFEALDNTAIYKDGDLNGDGQFNVGDLVLMNRYI
                     HGTYTFNEKQYKSADLNGDGNADVFDVIEFRKKILAD"
     PFAM_domain     13386..13556
                     /aSDomain="LRR_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13306.8"
                     /description="BspA type Leucine rich repeat region (6
                     copies)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_163_0056"
                     /evalue="8.30E-03"
                     /label="ctg1_163"
                     /locus_tag="ctg1_163"
                     /protein_end="129"
                     /protein_start="72"
                     /score="16.2"
                     /tool="antismash"
                     /translation="NIEEFTVPETINDVPVVGIEWGAFRNCKNIKKLTLTKNVSVINWG
                     DIAEFSMEEIAV"
     PFAM_domain     13644..13916
                     /aSDomain="LRR_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13306.8"
                     /description="BspA type Leucine rich repeat region (6
                     copies)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_163_0057"
                     /evalue="2.90E-20"
                     /label="ctg1_163"
                     /locus_tag="ctg1_163"
                     /protein_end="249"
                     /protein_start="158"
                     /score="72.6"
                     /tool="antismash"
                     /translation="SAAEVKIADEAENIAPYAFVSCQKLTKIEVSNNVGEIGEGAFVGC
                     TSLTSINIPDGVKAINTYTFAGTKALKGVRIPGSVDYMYNDAFKDS"
     PFAM_domain     15081..15344
                     /aSDomain="LRR_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13306.8"
                     /description="BspA type Leucine rich repeat region (6
                     copies)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_163_0058"
                     /evalue="6.50E-20"
                     /label="ctg1_163"
                     /locus_tag="ctg1_163"
                     /protein_end="725"
                     /protein_start="637"
                     /score="71.5"
                     /tool="antismash"
                     /translation="KKIVVPDGVKSIEDFAMLNLRNVESIELPDSLEEIKYGAFLDATK
                     LKSINLPENLDFIGDRAFNYCISLEDIKIPESVKGIGLYAFYD"
     PFAM_domain     15897..16049
                     /aSDomain="Dockerin_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00404.20"
                     /description="Dockerin type I domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_163_0059"
                     /evalue="2.40E-07"
                     /label="ctg1_163"
                     /locus_tag="ctg1_163"
                     /protein_end="960"
                     /protein_start="909"
                     /score="30.9"
                     /tool="antismash"
                     /translation="GDLNGDGQFNVGDLVLMNRYIHGTYTFNEKQYKSADLNGDGNADV
                     FDVIEF"
     CDS             complement(16260..19697)
                     /locus_tag="ctg1_164"
                     /transl_table=11
                     /translation="MKPKKNKRLVSVLVSACMALPFLTDSLPVLSPNIAAVKAEAAYGH
                     DDDLVLRYNSMAGYVNTDNAFNNDESFYKALPLGNGRIGAMAYGNYPDELFDLNECTVW
                     SSGPGNNNKEGAASHLSEVQNLIKSGKYNDANSIVARQMIGGGEAKYQKVGALKLSFGH
                     DKVSEYSRELDMNDAVARCSYTFNGKRYTRETFVSYPDQVMVTRITCDSKGSVSFSAGY
                     DGLLNGTVATEGNDTIVANGHADEDLWIRGAVYYSTRSKVIPEGGSISAGNGKVSVSGA
                     DSVVIITSVRTNYVDYKTCNGDEKGDAKADIAKAESKAYDTLYQNHVQDYQELFKRVDI
                     ELGGDTENAKKMTTPQRISDFGRSNDPKMVETLFQYGRYMMISASRDAQPMNLQGIWNK
                     YSAPAWGCKYTTNINYEMNYWPAFTTNLAECFEPFAEKAKGLAAAGNETARVNYGITEG
                     WVLHHNTDLWNRTGPIDGAWGQWPTGGAWVSNMLYDAYRFTQDKDYLSDIYPVIKGSAQ
                     FLNKLMIPATINGQEYMVISPSTSPEINLPAYPDDSVDQSLTMDNGIARELFKDVAEAS
                     EILGCDSELREQLNSKLTLIRPETIGKWGQIQEWAQDWDNQNEKHRHISHMYALYPGFE
                     ITPEDNPTTAKGASTSLNARGDDGTGWSEAWKLNCWARLEDGAHAYNLIKLLITPVNNY
                     GRLYDNLWDAHPPFQIDGNFGFTSGVAEMLLQSQNDVITLLPALPKQWSTGHANGLCAR
                     GNFEVTEMNWKNGRLENATILSKSGGVCTVRYSGAMISFETEAGKEYSLNGELQFDGEE
                     LQNLALGKKVTASGSDNGETPEMAVDGDASTKWYHADGIGGEWIQVDLEEECNIQRWSA
                     KFAGLNEKSTFDPRDFVLKASSDGESWTDITEVFGNTKSSCGRNLSGINARYVRLEMRT
                     STQDNSGGARVYELEIWGNNGKPPVPKTAYKNYGCSSYNFMRGEIRKDDSGNTAIGYIT
                     DGSYIVFRKLDFESGAEGFKVRAASATDGGTIEIRLGSADGDIIGKCDVPTTDGWDEYI
                     DLECATSQCTGEHDVYLVFRGGDGYLFNVNNFSFYGLSGDVNGDREVDIFDVLRFRKAL
                     IKQTELSGLGLSNSDLNSDSESNVADLLLLQKFMLGKG"
     PFAM_domain     complement(16275..16439)
                     /aSDomain="Dockerin_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00404.20"
                     /description="Dockerin type I domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_164_0063"
                     /evalue="6.20E-07"
                     /label="ctg1_164"
                     /locus_tag="ctg1_164"
                     /protein_end="1141"
                     /protein_start="1086"
                     /score="29.6"
                     /tool="antismash"
                     /translation="GDVNGDREVDIFDVLRFRKALIKQTELSGLGLSNSDLNSDSESNV
                     ADLLLLQKFM"
     PFAM_domain     complement(16452..16766)
                     /aSDomain="CBM_6"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03422.17"
                     /description="Carbohydrate binding module (family 6)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_164_0062"
                     /evalue="3.30E-29"
                     /label="ctg1_164"
                     /locus_tag="ctg1_164"
                     /protein_end="1082"
                     /protein_start="977"
                     /score="101.8"
                     /tool="antismash"
                     /translation="DDSGNTAIGYITDGSYIVFRKLDFESGAEGFKVRAASATDGGTIE
                     IRLGSADGDIIGKCDVPTTDGWDEYIDLECATSQCTGEHDVYLVFRGGDGYLFNVNNFS
                     F"
     PFAM_domain     complement(16884..17234)
                     /aSDomain="F5_F8_type_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00754.27"
                     /description="F5/8 type C domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_164_0061"
                     /evalue="3.30E-16"
                     /label="ctg1_164"
                     /locus_tag="ctg1_164"
                     /protein_end="938"
                     /protein_start="821"
                     /score="59.7"
                     /tool="antismash"
                     /translation="VTASGSDNGETPEMAVDGDASTKWYHADGIGGEWIQVDLEEECNI
                     QRWSAKFAGLNEKSTFDPRDFVLKASSDGESWTDITEVFGNTKSSCGRNLSGINARYVR
                     LEMRTSTQDNSGG"
     PFAM_domain     complement(18813..19544)
                     /aSDomain="Glyco_hyd_65N_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14498.8"
                     /description="Glycosyl hydrolase family 65, N-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_164_0060"
                     /evalue="6.70E-64"
                     /label="ctg1_164"
                     /locus_tag="ctg1_164"
                     /protein_end="295"
                     /protein_start="51"
                     /score="216.2"
                     /tool="antismash"
                     /translation="RYNSMAGYVNTDNAFNNDESFYKALPLGNGRIGAMAYGNYPDELF
                     DLNECTVWSSGPGNNNKEGAASHLSEVQNLIKSGKYNDANSIVARQMIGGGEAKYQKVG
                     ALKLSFGHDKVSEYSRELDMNDAVARCSYTFNGKRYTRETFVSYPDQVMVTRITCDSKG
                     SVSFSAGYDGLLNGTVATEGNDTIVANGHADEDLWIRGAVYYSTRSKVIPEGGSISAGN
                     GKVSVSGADSVVIITSVRTNYV"
     CDS             complement(20001..20654)
                     /locus_tag="ctg1_165"
                     /transl_table=11
                     /translation="MLNQLLGKLERKFGKFAIQNLMLYIIIGMGVFYIADMILSTNPDN
                     NIFLLDMIYFDRAKILAGEVWRVLSFLLMPPDYRLILMVFILYFYWLMGTQLEAKWGSF
                     KFNVYYFTGVIGCIIAGFITGFSTNAYLNLSVFLAFAVLFPEEEIYAFFVLPVKVKWLG
                     LIDAALLVYKFINGGYYVRIFIVLSIANFFLFFGKDFVQLMYYTGRRYYHKLKK"
     CDS             complement(20736..22799)
                     /locus_tag="ctg1_166"
                     /transl_table=11
                     /translation="MYFKTIARSIISFITSAVCLSTGAMSAFAAWELSFSRDIDVIGIN
                     ESITAADEEKELKYEETPIHSLIVSDLSPQIESDIDHAEWSFSEWENCHYIFLPATADS
                     KKLHIDYVCDEGEVFLNGEKVMSGEDTDILSKSDEFKVTTAKSTDCGILKILQSDRGSI
                     FMQSEDTSFDDLYNNRWLTVSAQALMLDAEGNTVYDGNVEKVTSHGNSSWDYSKKKPYN
                     IKLPKKADLFGMGKAKKWVLLSNYLDHSMLRNKITEEMCRAAGMEYTMDSVFIDLYADG
                     AYCGTYQLCEKVQIQKNRVNITDLEEETEKLNENDLKNYIRKVAGADTALDYMENSYKY
                     FDIPNDPEDITGGYLLQLIQWNRYGVKADSGFVTSRGQAVSIEGPEYASKAQVEYIRGF
                     VQDIEDAIYSDTGYNSKGKHYTDYIDLDSLVRAYLVQEISVNIDATFNSFYFWKDSDLK
                     GDGKLHFSPAWDFDLSYNNFNTSRTNSDGNTGWSSSFSNLFAAYFPIHGSSLTTPDSGR
                     PAEGLSWIGRLFKNNDFHYRVADIYFKDFEPFLKKLTGGDSPYLTEMANELSKSAEMNN
                     MLWHTYGGAKYCVFGSSSGETYLESVDIVRKFIEKRTNWLSSLWKNDRSKMGDINYDSE
                     INVADLLMLQKWLHGSGKTVYLENADENGDGVIDVFDLCRLRTEILEIQKDK"
     PFAM_domain     complement(20760..20918)
                     /aSDomain="Dockerin_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00404.20"
                     /description="Dockerin type I domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_166_0065"
                     /evalue="3.80E-07"
                     /label="ctg1_166"
                     /locus_tag="ctg1_166"
                     /protein_end="680"
                     /protein_start="627"
                     /score="30.3"
                     /tool="antismash"
                     /translation="GDINYDSEINVADLLMLQKWLHGSGKTVYLENADENGDGVIDVFD
                     LCRLRTEI"
     PFAM_domain     complement(20952..22181)
                     /aSDomain="CotH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08757.13"
                     /description="CotH kinase protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_166_0064"
                     /evalue="2.50E-31"
                     /label="ctg1_166"
                     /locus_tag="ctg1_166"
                     /protein_end="616"
                     /protein_start="206"
                     /score="109.5"
                     /tool="antismash"
                     /translation="SHGNSSWDYSKKKPYNIKLPKKADLFGMGKAKKWVLLSNYLDHSM
                     LRNKITEEMCRAAGMEYTMDSVFIDLYADGAYCGTYQLCEKVQIQKNRVNITDLEEETE
                     KLNENDLKNYIRKVAGADTALDYMENSYKYFDIPNDPEDITGGYLLQLIQWNRYGVKAD
                     SGFVTSRGQAVSIEGPEYASKAQVEYIRGFVQDIEDAIYSDTGYNSKGKHYTDYIDLDS
                     LVRAYLVQEISVNIDATFNSFYFWKDSDLKGDGKLHFSPAWDFDLSYNNFNTSRTNSDG
                     NTGWSSSFSNLFAAYFPIHGSSLTTPDSGRPAEGLSWIGRLFKNNDFHYRVADIYFKDF
                     EPFLKKLTGGDSPYLTEMANELSKSAEMNNMLWHTYGGAKYCVFGSSSGETYLESVDIV
                     RKFIEKRTNWL"
ORIGIN
        1 gatgatattg tcaatgactc ttatgagctt gtcctcgaaa ggaagatcgt tcagctcgtc
       61 accaagctcg tccagagcgg tcaggaacag ctgacttgac ttgtgagata caagcttgtt
      121 cctgatatca tacttatcct tgaaatacag gtaaaaagta ccctttgcca cacctgcctt
      181 gcttacgata tcagttatag aggtcttgct gaagcccttt gtggtgaaaa attcaaaggc
      241 ggttttcagc agcgagtttt ctttcagttt tttattcgca tctaccttac ccattatgac
      301 ctctcctttc attttatcct ttgtattaaa tactgtcctc actattatct gttgtcataa
      361 ttattatatc cctaaaaaca gaccctgtca agggtataaa attgaccaac agtcagctta
      421 tatgaggagt aaaattgtgc acccatacaa aattaatgac cgagggtcat tttttattct
      481 gaaatggttg actaacggtc atttttgtaa tatactatga aataacaaag gcacaggcgc
      541 acactgaatg tccgtgaggt cggttcagct tttacaattt cccatattaa agcttttctc
      601 ctaagggtat atactcacgg acgttcaata tgcgcctgaa tataacagaa aggatatgat
      661 aagatgctaa aactcggtga atggatagca aaacacagag cactcatact tgtggtctcg
      721 gtggtaatgc ttatccctgc ggcaatagga tatgtcaaga cacgtgtaaa ctacgacata
      781 ctctcttatc tgccgaagaa tataaataca atggtaggac aggatatcct gaaggagcag
      841 ttcggacaag gcggcttctc ccttgtaatg gtggagggca tgagcgataa agacgtggcg
      901 gcgactgccg acaagatagc ggctgtcgat catgtttcaa atgtagtatg ctatcagtcc
      961 atgacaggct gtactatccc gaaggagata cttcctgcgg atatatacga cttcttcaac
     1021 aagggcgaca ctacgatgat ggctgtattc tttgatgata cgacctccgc agacgctact
     1081 ctcaatgctg tagagacaat gaggagcata acttcaaagc agtgcttcat cagcggtatg
     1141 tcagcaatga ctcttgatat gaagaatatc acccagaatg agacgcttat atatgcgctc
     1201 atcgcagtta tcctcacaag tatcgtactt atgataacaa tggattcctt ccttatccct
     1261 gtattcttta tgctgagcat aggatttgca gtagtctgga acttaggctc caatatcttc
     1321 ctcggggaga tatcattcat cacacaggca cttgcaatgg tattgcagct cggtgttaca
     1381 atggactact ccattttcct atggcacagc tacaaggaac agcagaaatt ctatcccgac
     1441 agcagacagg aagcaatggc acacgctatt tcagctacta taacctcagt tgtaggaagc
     1501 tccttcacaa cagttgcagg cttccttgca atgtgcttca tgacattcac acttggtctt
     1561 gatttaggta tcgtaatggc aaagggcgtt gtatgcggcg ttatcgcctg cgtaactgtc
     1621 cttccgtcaa tgatactcat attcgacaag gctattgcaa agacctcaca taaggacttc
     1681 ttaccgggct ttaagcgtac atcttcattt atcgtaaagc attcatgggt attccttaca
     1741 ggagcgatag ttctcctgat acctgccgta ttcggcaaca gcaactacgg tgtttactat
     1801 aagcttgaca gcactcttcc aaagactctt gacagtgtta tcgcaaacac aaagcttgct
     1861 gaggaataca acatgaacag cacacatatc ctcatggtaa gatcggatat gagtgctaag
     1921 gacgcaaaca agatgatgaa caagatagaa agcgttgacg gcgttcagtt cacactgggc
     1981 ttcaattcac ttgttggctc ggctattccc gaggaagcag ttccgaagga gctcagaagc
     2041 gtactcaaga gcgatgaatg gcagctcata ctcataggtt ctgaatacga agtagcttct
     2101 gacgatgtaa acgagcaggt gggaactata aacaagatag ttcagaaata cgatcccaac
     2161 ggaatgctca tcggcgaagc acctgcaaca aaggacctta taaccataac cgacagagac
     2221 ttcaagatag taaacttcct ttcaatagct gctatcttcc ttataatcgc atttacattc
     2281 cgttcaatat cacttcctgt gatacttgtt tcggtaatag agcttgcaat aatgataaac
     2341 ctcggtttag cttactacac aggctcaaag ctctcattca tagctcctat cgttatcggt
     2401 actatccagc tcggtgctac tgttgactac gcgatactca tgacaacaag ataccgcacc
     2461 gagcgcagca gcggcaagga caaaaaggag tctatcggca ttgcactcag cacttctata
     2521 aaatctgtca ttacatcggc tctcggattt ttctccgcaa cagtaggcgt tgcactttat
     2581 tccgatatcg gtcttatctc agagctgtgt atgctccttg caagaggtgc gcttatctca
     2641 atggtaatag taattaccgt tctcccgtca atgttcatgg tctttgacaa ggtaatatgc
     2701 aagaccagtg caggattact tccaaagaaa aacaagtttg aatacagata caaaaacgca
     2761 taaaatagcc gaaggtttca tataaaggag agatagatat gaaaaaggta agtaaagtta
     2821 tggcagccct gattgcaacc gcagtatccg caggcgcaac aggctctatc gcatacgcaa
     2881 agagcagcgg aaaggtacag gagaccgctg aaaagacaaa ggaaacagac agtgcggaag
     2941 cctcttcaag aaaagacaac ggcgaaaacg catacaagga cgagacggtt tacgtcctct
     3001 gcaacagcga ttcaagcata aagaacgtag tagtaagcga ctggctgaaa aatgctcccg
     3061 cactgggaag tatctccgat atctcggagc tgagcgatat cgtcaatgtc aagggcgatg
     3121 aggagttctc attaaacggc gagaatatca gctggcaggc tgacggcagc gatatctact
     3181 acaagggcaa tacagataaa gaccttcccg ttgatgtgga tattgagtat actctcgacg
     3241 gcaagaaggt aactcccgaa agcatcaagg gcaagagcgg acaccttgtt atccgctgga
     3301 catacaagaa caatcagaag gtcacaaaga ccgtaaacgg caagacaaag gagctttatg
     3361 tgcctttcat ggcagcaagt gccgctgtgc tcagcacaga caattacctt aacgttgagg
     3421 tcaaaaacgg caaggtcatc tcagacggcg acagacttat cgttgtgggt atggcatttc
     3481 cgggacttgg cgaaagcctc gacctcagta agatagaggg aatgaacata gaaattcccg
     3541 acagcttcga gatttccgct gacgttacca attttgagat gaatacctct gttacagtag
     3601 tttcaaatga gatattctca cagcttgata tagataatgc tgccgatctc ggcgacttga
     3661 aggataagct caaggagctc agcgacggcg cagaaaagct cacagacggt acggctgcac
     3721 tttatgacgg tataaagaag ctaaatggcg gtgcaggaga gctgtcaagc ggcatagata
     3781 agcttctcag cggctctttg gagctgaaaa acggtgcttc ggagcttgac agcggtgcta
     3841 agaagttagc agacggcgca aagactctct cagactctac aggtacattt gaggcaggtc
     3901 tgggaagtgc aaaggacggc tcttcaaagc tggtggcagg tatagaacag cttagcggcg
     3961 gagcatcaca gctcagtgac ggcgcaggca gtgcaaaggc aggctctgcg gcactggtcg
     4021 acggcttcgg caaggtaagc gcaggtgcag acgctctcag cagcggtctc aaggacgcaa
     4081 aggacggctc cgatgctctt acagcaggct ttacaaaggt aaacgagggt gcagctgctc
     4141 tcaaggacgg agcaggcact cttacaagcg gcgtaggtgc tataaaggac ggcagcacac
     4201 aggtaaagga cggttctgca cagttggcag caggtgcatc tgcactcaac gacggagctg
     4261 caaagctcag cgagtccgca ggacagatgt cagcaggcat cacaagcgca aaaagcggtg
     4321 cagattctct tgcagagggc atagcaagcg cgaaaacagg tgcagatcag ctttcgggcg
     4381 gcgcatcagc tctcagtgag ggcgcagcaa agctcagcga cggcatcgca gcagcaggtt
     4441 catcacttga taccactatc gctgcaaacg agcaggctct tgcagcttta caggcattat
     4501 atcagcagtc tccttcacag gagcttgctg tggcaatagg aactcttcag cagactattg
     4561 aaggacagaa gcagatatca gcatctatgg ctgagagcgg tgctctcgga gcaggtgcag
     4621 cttccgtgaa gaacggtgca gcacagctta acggcggtat cggtcagctc agtacaggtc
     4681 ttgaagctgc aaagagcggc tctgagacat taaagggcgg tcttgcagca ctggatgatg
     4741 gcggcaaggc tttagcagca ggagcttcta cactttcagg ctctacagca cagctctcaa
     4801 agggcgcatc agatctgagc acaggtgcag cagctcttga cagcggtata ggtactcttg
     4861 caggcggcag cagtcagctt atcggcggac ttgattcgct catcgacggt atcggtcagc
     4921 tcagcagcgg caatgcttca cttaatgcag gacttggcaa gctcagtaca ggcgcagttg
     4981 atctcagcgg cggtatcggt cagctttccg acggtgcatc ggctcttgac agcggtcttg
     5041 cacagctctc acagggtaca cttacactta acggcggttt tggtcagtta agcacaggtg
     5101 cggtaactct tgatgacgga cttgcacagc ttttcggcgg cagcaagcag ctcagcggcg
     5161 gtgcaaagac tctttacgac tcaataaagc ttctcagcac aggcgcagct aagctcagca
     5221 gcggctcggg agagctttac agcggcgtgg acaagctcaa gatcggcagc aagactctct
     5281 cagacggagt aagtcagctt gaaagcggag ctaaggagct caacgacggc atgataaagt
     5341 tcaacaatga gggcatatca gtgcttacag gtgctgtgaa tgaaaatctc cctgatatca
     5401 tcgagaattt caaggctctg agagatgcat cgcgtgaata taacagcttc tcgggcatat
     5461 ccgataaaat ggacggcagt gttaagttca tctacctcgt tgacggaact aaatgagtga
     5521 ttagtagggg cgagttccgc gcgcccgtgt aaccccgatg ctaactcccc gtgtcgagaa
     5581 gcagctgccc ttttgatgat atgcggacga gtaagggtgc gcaggctctg cgcgtagggg
     5641 cgtgttccgc gcgcccgtta atcccgatga tacttcccgt gtcgagaagc aacgcctctt
     5701 ttgatgatat gcggacgagc aagggggcgc aggctctgcg cccatgtaac cctattccta
     5761 tgtatttaac ataaaaacat aagccatagt atttctgtat actatggctt ttttgttgtt
     5821 attctatttc ttgaacacca tgttgcatct gccccacatt tcatcgccgt aggcgaacgc
     5881 atcaggagtt gtgtgccttt cggtaaagcc tgcgctttcg tagcacttcc gcgctttttc
     5941 gttgacagta aacacgttta gctgtacagc gtccgctttc agtatctctg tgcagtattt
     6001 tgcggcaagc tgtatcattt ctctgccata gcccttaccg cgctgtgcag ggtctacgat
     6061 aacgaaagcc agcatagctt cattgctttc ggtgtttatg ccgcagcata gaaatcccac
     6121 gacttttccg tcatctgtag ttgccacaaa ggggcagtct ccgtgcttcg tgtacatatc
     6181 tgcaagaaac tggtcaaagg cgttcttttc aagtggatag ggagcatgtt tcgcgctcca
     6241 cattgcgtga gtgcgttcgt cggttatcca gtcctttatt gcgtcaaaat catggcttgg
     6301 tatgtatggt ctcagtctca tggtaacacc cctatgttaa ttaggaattc ggaatgctga
     6361 attaggaatt atatgtgttc gctgataaaa atgcaggggc tgcctttggc agcccgtttt
     6421 agatattttt ttcctgatgg cgcacaatgt gcgcccatac acggaacgcc gagggcggcg
     6481 ttccctacag ttacttatta tctgcttttc tctggaaata ctttactgct tccacgacag
     6541 gtactataaa tgcacccatt atgaatgcgc agaggtagtt ttcagcaaaa agctctgaaa
     6601 gtgagaacat atctctgagt gaaggtataa agagtatcgg tattgtaagt acagctgaaa
     6661 gtgcgatagc tccgataagg accttattgt gcttcttcat ggtgaagatg gagtctttaa
     6721 ggcttctcat attccatgcg tggagcatct cacatacgca gagagtgatg aatgccattg
     6781 tcatgcctgc ttcgtgacct tcgctgttaa agccgataac gtaggaaata agtgtgagta
     6841 ttgcgataac agtaccctgc cagagaagat ttatacccag accgtccgag aagatgtgag
     6901 aattgctgct tcgaggttta cgtgacatga tgccgttttc ggcaggctcc atgcccagtg
     6961 caatagcagg gaaacagtcg gatataaggt ttatccagag caggtgtaca gggttgaaga
     7021 gtacgaatga accgtctgta aggcttccga gacctattgt agcgataagt atgcagagca
     7081 cctcactgag gttgcttgaa agcaggaact gtatagcctt gcggatattg tcgtagatac
     7141 gtctgccctc ttcaacagct cctacgatag ttgcgaagtt atcgtctgtg agtaccatat
     7201 cagcaacgtt ctttgtaacg tctgtacctg tgatacccat accaacgccg atgtctgcgc
     7261 tcttgataga aggtgcgtcg ttaacgccgt cacctgtcat agcagtggtc atgccctttt
     7321 tgcgccaagc atttactata cgtaccttat gctcgggctg tacacgtgca taaacgctgt
     7381 agtcgccaac gtgctcgttg aattcttcat cgggtatctt tgaaagctct gcacctgtga
     7441 gagcctgctg acccttttcg aggataccga gctccttagc gatagcaacg gcagtatctc
     7501 tgtggtcgcc tgttatcata acaggacgta tgcctgctgt gcggcagaga ccgatagcgt
     7561 ccttgacttc gggacgaaca ggatctatca tacctgtcat gcctatgtat ataaggtcgt
     7621 gctcaagagc ttcgggagct gtatcagcgg ggagctcatc gtattcgcgg taagcagcaa
     7681 gcagtactct gagagcattg tctgccattt ccttgtttct gcggagtatc tcaagtctgt
     7741 cggactcggt cattatacgg actccgccct ccttgaacat atgtgtacag tttttcagca
     7801 cttcatctgg tgcgcccttt gtgtactgga tatagccctt gtcagtcttg tggactgtgg
     7861 acatcatctt tctcattgaa tcgaaaggag cttccgcaac acggggtgtc gcagcttcaa
     7921 gctcgtattt tttaagcccg catctgtgtg cgtaagctac gagagcagcc tctgtaggct
     7981 cacctgctac ggtatcgtcg gagttgagct gagcgtcaca gcaaagagcc atagcctttg
     8041 cgaggaattc cttatcgtct gtattttcct gaactacagt catcttattc tgtgtaagag
     8101 tacctgtctt gtccgagcat attacctgtg cgcagccgag agcttcaacg gctgtaagtc
     8161 tgcgtatgat agctccgcgc tttgacatat tggtaacgcc gatagagagt actacagtaa
     8221 caacggctgc aagaccctca gggatagctg caacagcaag gctgacagcg atcataaagg
     8281 attcaaggaa cttaggaagt gtgatagagc catctgcaat gagcatacgg actatattga
     8341 gtccgaggat aataatgcat ataacaagta cagctataga gagtatcttg ctgagctgat
     8401 cgaggctctt ctggagagga gtctcatcat cgtcggcatt agcgatagca cctgctatct
     8461 tacccatttc tgtcttcatg cctgtagcta ctacaacagc ttctgcacgg ccataagcga
     8521 tgctgctgcc catgtagagc atattctttc tgtcgccgag aggtacttcc tcgcctgtga
     8581 ggacttcgct gtccttatct gaaggtacgc tctcacctgt gagggctgat tcctcagcct
     8641 tcagtgcagc ggcttcaagt atacggcagt cagcaggtac gttgtcgcct gcttcgaggg
     8701 cgatgacatc accgggtaca agctctgagc ttggtataac tacaagctcg cccgaacgga
     8761 acaccttgct ctgtgcggca ctcatagcct gtaatgcctc gatggcagat tctgccttat
     8821 tttcctgata tactccaagc accgcatttg cgataacaac gaagagtatt ataaatacgt
     8881 ccgcgtcaag cttgccctct gatatgatgc ctgttattgc agatataaca gcagctgcga
     8941 taaggacgat tatcatcgga tttttgaact gttcgataaa acgagcaagc atagtcggct
     9001 taggcggttc atcgagtttg ttctttccgt tggtttcaag gcgctttgct gcctcttctt
     9061 ttgtaagacc tgataccgag ctgtcgactt ccttgagtac ggagtcagtg gattcaagat
     9121 aatgtttcat ttttcctccc ctaataattg tttggtttgt gatataataa aaactgcggt
     9181 caaggcatat acagtttaga tatagccttg aatgcagtac taaacagata aaattttatc
     9241 atttactgat aaaaaagtca agatataaaa gtgtttgaat agtgaaagta cagtgataag
     9301 attgcgaaat cgtataaact gtatttagag atgctcttta tataacaaaa gagcccgttc
     9361 ctcagagcag aaacagactc ttttgtctgg aagctgaagc ggagcttcct gtatgaaaaa
     9421 tcactgtatg atttacttcg aaacaagcaa atgaatggaa attctgattt gctattgtac
     9481 tttcaacggt ttttttattt atagagatgg ttttttagag agatctgaaa gcgtaatggg
     9541 gggttcactg tttgttccga gtgagatgac atacgaatga tcatcaacct tgtgttaggc
     9601 ggaagagtgt atctgccgat tgctcggcag atctcaattc cgttagggga tatgatgtat
     9661 tataaaagct gttggcgtga tcaatagtac aggcatcata aaagatgcag ccacaaaaat
     9721 taatatgact taatgcccat tttttaggtt cgtcttcccg aagagtgact gcacgatcat
     9781 ctgaccctgt cgattgattt ttctgagatc gttgcggtaa tgatgttaaa acctttattg
     9841 ggacatttgg tgttggttac tataatatag ttgtggtaaa tcaattgctg ctcggcgcat
     9901 cagataatga aaaatacgct tcaaatactg taattgtatg tagatattgc agtgaataat
     9961 gtaatagaga atcgattagc tgttttgtgt tttttatcgg ttagaatttt ctgaactttt
    10021 tgagatcttt tgggggagta ggctgattac ataaataaat acatgctgaa tttacatttt
    10081 gttctgcagc cttgatagat tttgtaacga tagttttcat tatttttgct ttgacagagt
    10141 cacaagaaaa cttcatttca gaaatacctc ctgttcaatg attgtgcgga caccttcggg
    10201 gtgacgcctt aagtatatta tatttatatc ctcgaaaaag tcaagggctt tgcactaaac
    10261 gccgtttatt tgcattttta gtatcaaatc attaaaatat tatatgtttg tgtgcacttt
    10321 ttgtaacata tccttactgt ccgaagtttc ggggataggg ataagaattt cggttataaa
    10381 catatcgttt tctgtatgtg cattgaagtt gccgttgtat ttttcgcagg cacttttgat
    10441 atttgacaaa ccgatgccct gatgaccttt cttggtgctc ctgaaaactt ttttaacgtc
    10501 ctgattaact tctgcaaaag tattttccac atatatgaat acgaagtaat tacgtcttgc
    10561 gatggagagc gttacatgac gtttttcttc aggaagctcg gcacaggctt caaaagcatt
    10621 gtccagcaga tttgagaaaa tagctgtaat atcgaggttg gatatgaaat ttatctcggt
    10681 aaactcagca tttaccctga aatccacctt catattgtcc gcagcctcga gcttgttgtt
    10741 tataacaacg gtaagaatag agttgtcaca ctcaaagcgt ggcatgagct tgttgagctc
    10801 atagttcagc atatctctgt atttacctgc ttcgtctgct ttgtttgcgg ttataagacc
    10861 ttcaagtgag gcgagatgct ttcttacgtc gtgtattacc tttcttgaag ctatgtattt
    10921 ttcgttaagc ttattatatg cattcagctg caaggtggac tgctgggtaa ggagctccag
    10981 cttcttttcg gtcttgtaag cctttgacat acggtttata agataagtaa ggtaaagatc
    11041 caagagcagg aatataagca gtattattac tacctcatat ctgttctttg attcggaaat
    11101 aatatccgtc aggaaattaa aaagtattat ttcgcctata ataagaccga cgaacattat
    11161 gacttcctgt gtgcgtacat tattcatgcc tttttcggaa ttgatattta caaagacctt
    11221 tgcaagcgca agcatgatta tccagttcat gagtgcggtg gcagcaaaag aatagggctt
    11281 atccgttatt ctctcaacgg gaacattgat tatcagtgca atgataaagg ctgttatcat
    11341 ttcaacgatc agcattatga cgaagatgat cgcatcgtaa ataagaaagc tcttactggt
    11401 gggcttgaag aatattacat tgaacagtat caccgataag aacgagaatg agaaattcaa
    11461 tatatttatc ttgaatgttt taatgtatgc cattatcaat gcagctgcaa tgataaaaag
    11521 aatacggaaa aaaatattga tcttttttaa cggatatatt ttttcataaa gaacataggt
    11581 aaaaacgtaa aatgcgataa gtgttgccag ttcgatcaaa aacatcatga tctgtatcac
    11641 ccctgcctta tatagttttt aatgaaacgg ctgaattcat tgtgaaattc cttgagcttt
    11701 ttctgcgcca cgggaacttc gataccgttg gtagtatata atgtaaagtt gttgagcttg
    11761 tctatgtgtt ccatattaac tataaagctt ttatggggtg aaacgaagct ttcagagttg
    11821 ataatactga aaacatcgga aaggctgcct tttatctggt atttttcgga ttctgtgtat
    11881 acagttatcc tgcggttgcc tgtatattca aatacataga tatttttaag gttaagcaga
    11941 agaggaccgt cctcgccctt cagctgtatc acggtatcct ttgcggaatt ttccgacaga
    12001 tactttgtaa gctcaccaag aacgctgaaa atacggctgc tttcaaaggg ctttacaacg
    12061 aaatcgaatg ggtgtacggc atagctttgc agagctaatt ccgagtgatt tgtgacatag
    12121 actattcttg cgcgtctgtc tatctgtctg tagagctgag ctgttttcag accgtccatg
    12181 ccgcccattt caatatcgag gaatataaga tcaaaatcca gtttgcagtc gagcagcttt
    12241 tcaccgctct ggaagctgtg tacctcaaat tcgatggcat gagttttgct gtagctcgaa
    12301 atagcggatt tcaaagcctg tatcatgtca ttgtcatcgt cacagatagc aatattaatc
    12361 atttttccac tccttttctg ttacttatac gacctgcaac aagcaggaag gcggtaacga
    12421 atactgccaa tgataacgaa agcgtaagta tgtacagcct gaacacagct gagataacgg
    12481 caagtgctgt tcctaaagca gtgatcatca gtgaccgtct gcggaatacc ctgcgttcgg
    12541 tatcatcaaa gggcttggtc ggcgtttctg tcggtgcagc aaaaaggatc accactattc
    12601 cagaaaataa aaatgccgcc gaaacataca gcctttcagg gtcatgtatg agctttgacg
    12661 cagctataac tgcggcaagc attactacgg atatcataaa gcagcctaac cttgaggctg
    12721 agtgataccc cccgcagcaa ttcctcatcg gcatatacaa tgccagaaat actatcacgg
    12781 caataaagct tttcatcagg atcgccgtaa ttatcataaa agcggtagtg agtgtcgtca
    12841 ttatggtgag ttcaagtccg tatcgaacaa tttctgcatc ttcttctttt gcatatccgc
    12901 tgctaaggag cttttccatt atagcatcga gtatcctatc cattcttaat atccctatac
    12961 tccttttcaa agtgatgctt gcgaatcttg ttgcgataaa attactaaat tatgttcttt
    13021 ctgttatcag attaattata tatcaaatag cgataaaaag tcaagtcgtt tcagactgaa
    13081 aattgttgac atatggaaaa actgttgata taatattata tatatatcgt atgatattat
    13141 gatataatga tataggaggt aaaaataata tgaaaatcaa gggatttatt tcacttcttg
    13201 ccgcacttac tgttataaca agttctgtgg cagctgtacc gttcagcgca tctgctgagg
    13261 tagtttcaga aactgagatc gccgcagagt atgatttcag cggcgtttcg tcaactgtag
    13321 aaaaggacgg tgtaagctat agtatcttca aaggatatgc ggctgttcat tacgtcaatg
    13381 atgaaaacat cgaagaattc acagttcccg aaacaataaa tgacgttcct gttgtaggta
    13441 tagaatgggg tgctttcaga aactgcaaaa acatcaaaaa gctgactctt acaaaaaatg
    13501 tcagcgttat aaactggggt gatattgcag aattcagcat ggaagaaata gctgttaccg
    13561 aggataacga gtcgtttaca gttgttgacg gcgtacttta cagcaaggac atgaaaacag
    13621 tcgttgcttt tccgccttca aacagtgccg ctgaggtaaa gatagccgac gaagcagaga
    13681 atatagctcc atacgctttt gtaagctgcc agaagcttac aaagatagag gtaagcaata
    13741 acgtaggaga aataggtgaa ggagctttcg taggctgtac atctctcacc tccataaata
    13801 tacctgacgg tgtaaaagct ataaacacgt acactttcgc aggcacaaag gctctgaaag
    13861 gcgtaaggat acccggctct gttgattata tgtacaatga cgctttcaag gattcgggag
    13921 ctatcgaaaa cgagggcggc atacactacg ttgacaagtg ggctgtagga gctgataatg
    13981 atatagaacg tgctgatata cgtatgggca cagtaggtac tatggaagga ctcttcgtat
    14041 caaaaaataa gctgagagta gttacagtac ctgattctgt tatacatctg ggaagctacc
    14101 ttgttttcgg actgtataca cctgtcgaac tggtagagtt ccactgtcct gctatccctg
    14161 caagagtact tggctgcctt agtgtaaagg aagtatggat atatgaccgc aactgtaaga
    14221 tagaggacga tgcatcatcg cttcctacat actggagaga gccgaaggaa gctcctgagg
    14281 aagaagaaac caccgaagag aatgactata ttatcagaca tactcgggtt actgcttctt
    14341 caagcagcgg tgctaactca attgcaaaag ttataaatac ttcacttacc gaaattgatg
    14401 aagaagatga tgatgcaggt gaaataacta ccataactca ttctgtcaac acttcgagca
    14461 ctgattcaaa attcaaagaa aaagttgaag catacatgga gaaatatagg gaaaaacttt
    14521 ctcagaatac tgaggacaac tcaggtgttg cagttgcaca gcctgtagaa aaggtataca
    14581 aatcacctat aaagataggc aatcctgcaa agtatgatac cattatccgc ggatttgaac
    14641 gctctactgc agaggagtat gctctcaaat acagaagggt atttgatact tttgagcctg
    14701 caagcactgt tgtaggacct gagagtgtta ccgatcacga aaacagtgat attgaataca
    14761 gagtatacgg caacagctat gctattgcat cgctcaggga cggatatcac cccgacggtt
    14821 ctaatcgcaa aaaggaaata actatagctg aggagataaa tggtgttcct gtaacagcat
    14881 accgtctggg aggcggcgac gcagatataa ttcatctccc gaaaactgta agcaccattc
    14941 tttattctgt ggacgtggct accagctata actgctctta cgatatagac aaggataatc
    15001 cttatctcac atcagttgac ggaatcatct acagtaaaga catgacaaag ctcataaaag
    15061 tgccgtcaag atacgaagga aagaagatag tcgttcctga cggagtaaag agcattgagg
    15121 actttgctat gcttaacctt agaaacgttg agagcattga gctgcctgac agccttgagg
    15181 agataaaata cggtgctttt ttagatgcaa caaagctgaa gagcataaat ctccctgaga
    15241 atctggattt tatcggtgat cgtgcattca attactgcat ttctcttgaa gatataaaga
    15301 tacccgaaag tgtaaagggt atcggtctgt atgcttttta tgatgttcct gctgtcaatt
    15361 atgagggcgg tcttgggtat ctcgacaact ggttagtaga ggcagaagct gatgacaaac
    15421 cgaatatgat agtcccaaaa gagggcatca ccggaatggc gagagtatgc gctaaggatt
    15481 cgctggtcat tcccaagagc gttacaaaga tgggctggga agttcttggt ctttataaca
    15541 gtatcacaag agctgacgtt tattctcacg ttatcgacta tgatgcattc aagaacgcca
    15601 gatacctgaa ggatatatac atctacgacc ccgagtgcga gatttgcgca ggcgatcaga
    15661 ctatccctgc aaagtatatc gacacggata acagagtaat aaaaaagttt gatgaattgg
    15721 ttcccgacat aaagagcctg aatgcaagaa catacgcgta tgagcttaaa gcaggcgacg
    15781 gcgagaagct gggcgacacc gttatccacg gctacaaggg ctctactgct gaggcttatg
    15841 ctcagatgta cggcatcaag tttgaggcac tggacaatac ggcaatatac aaggacggcg
    15901 acctcaacgg cgacggacag ttcaacgtcg gcgatctcgt tcttatgaac agatatatcc
    15961 acggtaccta tacattcaat gaaaagcagt ataagtccgc tgaccttaac ggtgacggaa
    16021 atgctgatgt atttgatgtg atagaattcc gcaagaagat actggcagac tgataaataa
    16081 aataagagcc gcttccgata accatgtcag aagcggcttt tttaattcat aattgatgtc
    16141 gtttacgatg atactccccg tgtcgagaaa caactacctt tttgattaga tacgaacgag
    16201 caagggtgcg caggctctgc gctttagggg cgcacaattg tgcgcccctg atcatatatt
    16261 caaccctttc ccaacatgaa tttctgtaat agcagcaagt ctgctacatt tgattcgctg
    16321 tcgctgttca gatcagagtt ggacagtccg agaccgctga gctctgtctg tttgataagt
    16381 gcctttctga aacggaggac atcgaatatg tccacttccc tatcgccgtt tacatcccct
    16441 gaaagaccgt aaaaactgaa attattcaca ttgaaaagat atccgtcgcc gccgcggaat
    16501 acgagataaa cgtcatgctc gcccgtacac tgagatgttg cacattcaag gtcaatgtat
    16561 tcgtcccatc cgtctgtggt gggaacatcg cattttccta tgatatcgcc gtcggcagag
    16621 cctaagcgta tctcgatagt gccgccgtct gttgcacttg ccgcacgtac cttgaagccc
    16681 tctgctccgc tttcaaaatc aagcttgcgg aagactatat aagagccgtc ggtgatatat
    16741 cctatagcgg tatttccgct gtcgtccttg cgtatctcgc cgcgcatgaa gttatagctg
    16801 ctgcagccgt agttcttata cgcagttttc gggacaggcg gtttgccgtt attgccccat
    16861 atctcaagct cataaactct tgcgccgccg ctgttgtcct gagttgaggt gcgcatttcc
    16921 agccgcacgt atcttgcatt gattccgctg agatttctgc cgcaggagct ctttgtattg
    16981 ccgaatacct cggtgatatc agtccagctc tcgccgtctg agcttgcttt cagtacgaaa
    17041 tctcgcgggt cgaaggtgct tttttcgttg agacctgcga atttcgcgct ccagcgctga
    17101 atattgcatt cctcttcaag gtctacctgt atccattcgc cgccgatgcc gtcagcgtga
    17161 taccactttg tggaagcatc accgtcaact gccatttcgg gagtctctcc gttatcgctg
    17221 cccgaagctg tcaccttttt gccgagagca aggttttgca gctcttcgcc gtcaaactgc
    17281 aattcaccgt taaggctgta ctccttgcct gcctctgttt caaagcttat catcgcgccg
    17341 ctgtatctta cggtacaaac gccgcctgat tttgagagta tagtcgcatt ttcaagtctg
    17401 ccgttcttcc agttcatctc tgttacttca aagtttccgc gcgcgcagag tccgtttgcg
    17461 tgacctgttg accactgctt gggaagagca gggagaagtg ttataacgtc attctgactt
    17521 tgcaggagca tctccgcaac gcccgatgta aagccgaaat tgccgtctat ctggaaaggc
    17581 gggtgtgcgt cccagaggtt atcgtaaagt ctgccgtagt tgtttacggg agtgataagg
    17641 agctttataa ggttgtatgc atgagcaccg tcctcaagtc ttgcccagca gttgagcttc
    17701 catgcttccg accagcctgt accgtcgtcg cctcgcgcat tgagtgatgt ggaagcaccc
    17761 tttgcagtag ttggattatc ctcgggagtt atctcaaatc cgggataaag tgcgtacata
    17821 tgggagatat gacggtgctt ttcgttctga ttatcccaat cctgtgccca ttcctgtatc
    17881 tgtccccatt tgccgatagt ttcgggtctg ataagggtga gctttgagtt gagctgttct
    17941 ctcagctctg aatcgcagcc aagtatctct gaggcttctg caacgtcctt gaaaagctca
    18001 cgggcgatgc cgttgtccat agtaaggctc tggtcaacgc tgtcatcggg atatgcaggg
    18061 agatttatct caggcgatgt actcgggctt attaccatat actcctgacc gttaatggtg
    18121 gcaggtatca taagcttgtt gaggaactgg gcactgccct tgataacagg gtagatgtcg
    18181 ctgaggtagt ccttgtcctg agtgaagcgg taagcgtcat agagcatatt tgatacccat
    18241 gcgccgcctg tgggccactg tccccacgca ccgtctatag gacctgtcct gttccagagg
    18301 tcggtgttat ggtggagcac ccagccctct gttatgccgt aattcaccct tgcagtctca
    18361 tttcccgcag cagccagtcc cttcgccttt tccgcaaatg gttcaaagca ttccgcaagg
    18421 ttggtggtga atgcaggcca gtaattcatt tcgtaattta tattcgttgt gtatttgcag
    18481 ccccatgcag gagcggagta tttattccat atgccctgta ggttcatagg ctgtgcgtca
    18541 cgtgacgcac ttatcatcat ataccttccg tactggaaga gagtctcgac cattttcggg
    18601 tcgttggagc gtccgaagtc ggagatgcgc tgaggagtgg tcatcttctt ggcgttttcg
    18661 gtatcgccgc ccagctctat atcaacgcgc ttgaaaagct cctgatagtc ctgtacgtgg
    18721 ttctgataga gggtatcata ggcctttgac tcagcttttg cgatatcggc ttttgcatcg
    18781 cctttttcat cgccgttgca ggtcttgtag tctacgtagt ttgtacgtac agacgtgatt
    18841 ataactacgg aatccgcgcc cgagacggac acttttccat tgcctgcgct gatacttccg
    18901 ccctcaggta tgaccttgct ccgcgtggag taataaactg cacctcttat ccagagatcc
    18961 tcgtcggcgt gaccgttagc aacgatagtg tcattgcctt cggtagctac agtgccgttg
    19021 agcagaccgt catagcctgc cgaaaacgat acagagccct tgctgtcgca ggttatgcga
    19081 gttaccatga cctgatcggg atagcttacg aaggtctcac gggtatacct cttgccattg
    19141 aaggtgtagg agcatcttgc aactgcgtca ttcatatcca actcacggga atattccgac
    19201 accttatcgt gtccgaagct gagcttcagt gcgcctacct tctggtattt agcctcacct
    19261 ccgcctatca tctgacgggc aactatggaa ttggcgtcgt tgtactttcc gcttttgata
    19321 aggttctgca cctctgaaag atgcgatgct gcgccttcct tgttgttatt gccggggccc
    19381 gagctccaga cagtgcattc attcaggtcg aacagctcgt cggggtaatt tccgtaagcc
    19441 attgcaccga tacggccgtt tccgagaggg agagccttgt agaatgattc gtcgttgttg
    19501 aatgcattgt cggtgttgac ataccctgcc atgctgttgt agcgaagcac aagatcatcg
    19561 tcgtgaccgt aggcggcttc tgctttgaca gcagcgatgt tcggcgatag tacgggcaga
    19621 ctgtcggtga ggaacggcag cgccatacag gctgaaacaa ggacggatac gagccttttg
    19681 tttttctttg gtttcattca atcccaactc cttttttgcg tatttttata caattccttc
    19741 tatattttgc acaataatat ttgtgcatct ttatcttttt attaaattct atcacggagc
    19801 actaaaagtg tcaatgaaaa tagctgaaat tctacgtaat atccacaatt agagtgctta
    19861 ttttgcaaaa agagaataaa aaaagtcata attttatttg tgcagcttaa ataaaagaaa
    19921 tggtggtatg ttaatttaac tttgtaaaaa atatgaagaa aagccccctt gatttttcaa
    19981 gagagctttg gtgctttatg ttattttttt aatttgtgat aatagcgtct gcctgtatag
    20041 tacatgagct gtacgaagtc cttgccgaag aacaggaaga aattcgctat tgaaagtacg
    20101 atgaatatgc ggacgtaata gccgccgttg ataaacttgt aaacaagcag ggcagcgtct
    20161 atgagaccca gccactttac ttttacggga agtacgaaga atgcgtatat ctcttcttcg
    20221 gggaagagca ccgcgaatgc gaggaatacg ctgagattga ggtaggcgtt tgttgagaag
    20281 cctgttatga agcctgctat tatacagcct atgactcccg tgaagtaata gacgttgaat
    20341 ttgaagcttc cccatttggc ttcaagctgg gtacccatga gccagtagaa atacagaatg
    20401 aataccatga gtatcagccg ataatcggga ggcatcagca ggaatgaaag gactcgccag
    20461 acctcgcctg caagtatctt tgcgcggtcg aagtatatca tatccagcag gaaaatattg
    20521 ttatcggggt tggttgagag tatcatatcg gctatgtaaa atacacccat tccgattatg
    20581 atatacagca tcaggttttg tatggcgaac tttccgaatt tccgttcgag cttgccgaga
    20641 agctggttga gcattgacat tcctcatttc ttagtagtaa atagcagtat aagtaagtat
    20701 atcacgctca cgggctttct gtcaagcaaa agctgttatt tatccttctg tatttccagt
    20761 atttccgttc ttaaacgaca caggtcgaac acatctatta cgccgtcgcc gttttcgtcg
    20821 gcattttcaa gatatactgt ttttccgctt ccgtgcagcc atttttgcag cataagaagg
    20881 tctgccacat ttatctccga gtcgtagttt atatctccca ttttcgacct gtcgttcttc
    20941 cagagagagc tgagccagtt tgtgcgcttt tctatgaatt tgcggactat atccacagac
    21001 tcgaggtaag tttcaccgct tgatgaaccg aatacgcagt atttcgcgcc accgtaggtg
    21061 tgccagagca tattattcat ttctgcggac ttgctgagct catttgccat ttccgtaagg
    21121 taaggtgagt cgccgcctgt aagctttttc aggaagggct cgaagtcctt gaaatagata
    21181 tctgcaactc tgtaatggaa atcattgttt ttgaagagcc tgcctatcca gctcaagccc
    21241 tcggcaggtc tgccgctgtc gggagttgtg agcgatgaac cgtgtatggg aaaatatgcg
    21301 gcaaagaggt tgctgaatga tgatgaccag cctgtatttc cgtcggaatt tgtccttgaa
    21361 gtattgaagt tgttatagct gaggtcgaaa tcccatgcag gtgaaaaatg aagcttgccg
    21421 tcgcctttaa ggtcggagtc cttccagaag tagaagctgt tgaaggtagc gtctatattc
    21481 acggatattt cctgcacaag ataagccctt acaagggaat caaggtcgat ataatcggtg
    21541 tagtgctttc ccttgctgtt atagcccgta tcggagtata ttgcgtcctc aatgtcctga
    21601 acgaagccgc ggatatactc cacctgcgcc tttgaggcgt actcaggtcc ttcaatggac
    21661 acagcctgtc cccgtgaggt aacaaagccg ctgtctgctt ttacgccgta tctgttccac
    21721 tgtataagct gcaaaagata gccgcctgtg atatcctcgg gatcgttggg aatatcgaag
    21781 tatttatagc tgttttccat atagtcaaga gccgtatctg cgcccgcgac cttacggata
    21841 tagtttttca ggtcgttttc gttaagtttt tcggtctctt cttcaagatc ggtgatattt
    21901 acgcggtttt tctgtatctg taccttttcg cagagctgat atgttccgca gtaagctccg
    21961 tctgcgtaaa ggtcaatgaa tacggaatcc atagtgtatt ccatgcctgc ggctctgcac
    22021 atctcctcag tgatcttatt gcggagcatg gagtggtcaa ggtagtttga taggagtacc
    22081 cattttttag ccttgcccat tccgaacagg tcggcttttt tcgggagctt tatattatat
    22141 ggttttttct tgctgtaatc ccatgaggaa ttgccgtgag aggtcacctt ttctacattg
    22201 ccgtcgtata ctgtatttcc ctcagcatcg agcataagtg cctgtgctga gacagtcagc
    22261 cagcggttgt tgtaaaggtc atcgaagctt gtatcttcac tttgcatgaa gatgcttccg
    22321 cggtcggact gcaatatttt cagtattccg cagtctgtac tctttgctgt tgtcaccttg
    22381 aattcgtcgc ttttggaaag tatatccgta tcctctccgg acattacctt ctcgccgttg
    22441 aggaatacct ctccctcatc gcaaacatag tctatatgca gctttttact gtcagcagtt
    22501 gcaggcagga agatataatg gcagttctcc cactcactga atgaccattc tgcatggtcg
    22561 atatccgact cgatttgagg tgacagatct gaaacaataa ggctgtgtat gggagtttct
    22621 tcgtatttca gttccttttc ctcatcggcg gcggttatgc tttcgtttat acctattacg
    22681 tcaatatcac gggaaaaaga cagctcccat gcggcaaaag cggacatagc tcccgtactg
    22741 agacaaactg cggatgtaat gaaagatatg atagatcttg ctatagtctt gaaatacata
    22801 aaaacttccc ccctaaaata aacgtttcta tatattagtc gtttgaaaac ggaaaaaatc
    22861 tcaccctttt tcaaaaataa cagaaaattt acgcagaagt attccgccca aaatgtaaaa
    22921 ctactgcatc acatcaaagc ctg
//
