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Overview
1.1
8.1

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_DF158896.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | ranthipeptide | 81,699 | 103,351 |

NZ_DF158903.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 8.1 | lassopeptide | 1 | 5,955 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | ranthipeptide | 81,699 | 103,351 |
Region 8.1 | lassopeptide | 1 | 5,955 |

No secondary metabolite regions were found in these records:
  NZ_DF158897.1
  NZ_DF158898.1
  NZ_DF158899.1
  NZ_DF158900.1
  NZ_DF158901.1
  NZ_DF158902.1
  NZ_DF158904.1
  NZ_DF158905.1
  NZ_BAGW01000044 (original name was: NZ_BAGW01000044.1)
  NZ_BAGW01000043 (original name was: NZ_BAGW01000043.1)
  NZ_BAGW01000042 (original name was: NZ_BAGW01000042.1)
  NZ_BAGW01000041 (original name was: NZ_BAGW01000041.1)
  NZ_BAGW01000040 (original name was: NZ_BAGW01000040.1)

Compact view
NZ_DF158896.1 - Region 1 - ranthipeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 81,699 - 103,351 nt. (total: 21,653 nt) Show pHMM detection rules used
ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or YcaO or TIGR03882)))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ranthipeptide | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000599.1 |  | 0.15 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0000841.1 |  | 0.13 | Other (Non-NRP beta-lactam) | alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate, clavulanic acid | Streptomyces clavuligerus ATCC 27064
BGC0000695.1 |  | 0.12 | Saccharide | fortimicin | Micromonospora olivasterospora
BGC0000807.1 |  | 0.12 | Saccharide | phosphonoglycans | Stackebrandtia nassauensis DSM 44728
BGC0000885.1 |  | 0.11 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0000662.1 |  | 0.11 | Terpene | grixazone | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001151.1 |  | 0.11 | Other (Non-NRP beta-lactam) | valclavam, (-)-2-(2-hydroxyethyl)clavam | Streptomyces antibioticus
BGC0000723.1 |  | 0.10 | Saccharide | β-D-galactosylvalidoxylamine-A | Streptomyces hygroscopicus subsp. limoneus
BGC0000937.1 |  | 0.09 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0000679.1 |  | 0.08 | Terpene | diazepinomicin | Micromonospora sp. M42

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000599.1 |  | 0.45 | RiPP | thuricin CD α, thuricin CD β | Bacillus thuringiensis
BGC0000841.1 |  | 0.42 | Other (Non-NRP beta-lactam) | alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate, clavulanic acid | Streptomyces clavuligerus ATCC 27064
BGC0000695.1 |  | 0.40 | Saccharide | fortimicin | Micromonospora olivasterospora
BGC0000807.1 |  | 0.40 | Saccharide | phosphonoglycans | Stackebrandtia nassauensis DSM 44728
BGC0000885.1 |  | 0.37 | Other | 4-hydroxy-3-nitrosobenzamide | Streptomyces murayamaensis
BGC0000662.1 |  | 0.37 | Terpene | grixazone | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001151.1 |  | 0.37 | Other (Non-NRP beta-lactam) | valclavam, (-)-2-(2-hydroxyethyl)clavam | Streptomyces antibioticus
BGC0000723.1 |  | 0.35 | Saccharide | β-D-galactosylvalidoxylamine-A | Streptomyces hygroscopicus subsp. limoneus
BGC0000937.1 |  | 0.33 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0000679.1 |  | 0.30 | Terpene | diazepinomicin | Micromonospora sp. M42

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_DF158903.1 - Region 1 - lassopeptide
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 5,955 nt. (total: 5,955 nt) Show pHMM detection rules used
Region on contig edge.
lassopeptide: (PF13471 and Asn_synthase or micJ25 or mcjC)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Lasso peptides
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

No matches found.

No matches found.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lasso peptide predictions
Lists the possible core peptides for each biosynthetic enzyme, including the predicted class. Each core peptide shows the leader and core peptide sequences, separated by a dash.
Lassopeptides - No core peptides found.
Lasso peptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of disulfide bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.
No core peptides found.