LOCUS       NC_013720.1            10978 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_013720.1 Pirellula staleyi DSM 6068, complete sequence.
ACCESSION   NC_013720
VERSION     NC_013720.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:21:40
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1173917
            Orig. end    :: 1184895
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10978
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1178917:1179895](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5978
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10978
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10978
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="3"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             complement(106..1020)
                     /locus_tag="ctg1_939"
                     /transl_table=11
                     /translation="MRFVVFFALLLATSLASAAPPSLICCGMDEVFIIPATPGKLGESD
                     KLWSWTAASSPEIPQSQHAQFRTTDECKPYDKWILITSSSGGVALVERDTKRAIYVASA
                     RNAHSACLLPEKRIAVASSFGGDELLIFSYSDPASTTPIARTKLVGAHGTWWDVDGGKL
                     YALGSEELLLVSLKTSAATDKTALPTLEIVVEKTWQLPEGDGHDVSPTAGGKSLLITSA
                     SKIHTLDLKSQTFAPFELFPEAKKVKSIDQHRESKRFVLQQADLTSNNWWSNSLQLLDP
                     LEKIELPDERLYKARWDQPLAVP"
     PFAM_domain     complement(130..888)
                     /aSDomain="DUF6528"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF20138.1"
                     /description="Family of unknown function (DUF6528)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_939_0025"
                     /evalue="8.80E-14"
                     /label="ctg1_939"
                     /locus_tag="ctg1_939"
                     /protein_end="297"
                     /protein_start="44"
                     /score="51.2"
                     /tool="antismash"
                     /translation="DKLWSWTAASSPEIPQSQHAQFRTTDECKPYDKWILITSSSGGVA
                     LVERDTKRAIYVASARNAHSACLLPEKRIAVASSFGGDELLIFSYSDPASTTPIARTKL
                     VGAHGTWWDVDGGKLYALGSEELLLVSLKTSAATDKTALPTLEIVVEKTWQLPEGDGHD
                     VSPTAGGKSLLITSASKIHTLDLKSQTFAPFELFPEAKKVKSIDQHRESKRFVLQQADL
                     TSNNWWSNSLQLLDPLEKIELPDERLYKARW"
     CDS             complement(1274..2386)
                     /locus_tag="ctg1_940"
                     /transl_table=11
                     /translation="MKSICRTLASFVALASIACASLATAADDAAVYQQTVSKAVTYLTT
                     KAQAADGSYNSAAGPAVTALVTASLLKHGRTVDDPAVAKALKYLQQFVQEDGGIYAPES
                     NHKNYETCLGVVCFAAANKDGRFDTIVKKADAFVKGLQWDDKEGKTAADPEFGGAGYGK
                     NKRPDLSNTSFLLDALKATGTDPNSEEMKRALIFVSRCQNLESEHNTTPYAAKNPDGGF
                     YYSPAAGGVSQAGTTETGALRSYASMTYAGLKSMIYAGVGPDDVRVKAAIGWLKKNYDL
                     DSNPGMGTSGLFYYYQTFAKALEATGNDTFVDEKGVEHNWRSELIAELASRQAEDGSFV
                     NADPRWMEGDASLVTGYALLALAHSKPATK"
     PFAM_domain     complement(1739..2206)
                     /aSDomain="SQHop_cyclase_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13243.8"
                     /description="Squalene-hopene cyclase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_940_0026"
                     /evalue="3.10E-06"
                     /label="ctg1_940"
                     /locus_tag="ctg1_940"
                     /protein_end="216"
                     /protein_start="60"
                     /score="26.6"
                     /tool="antismash"
                     /translation="AVTALVTASLLKHGRTVDDPAVAKALKYLQQFVQEDGGIYAPESN
                     HKNYETCLGVVCFAAANKDGRFDTIVKKADAFVKGLQWDDKEGKTAADPEFGGAGYGKN
                     KRPDLSNTSFLLDALKATGTDPNSEEMKRALIFVSRCQNLESEHNTTPYAAK"
     CDS             complement(2760..3047)
                     /locus_tag="ctg1_941"
                     /transl_table=11
                     /translation="MRVVPIGDKVVVKRMTREEKTSGGIVLPGAAQEKSQEGRVLSVGD
                     GRLLADGTRAAVQVSEGDRVVLSPWAGTEIKVADEELLIVSEEDILAVLD"
     PFAM_domain     complement(2769..3041)
                     /aSDomain="Cpn10"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00166.23"
                     /description="Chaperonin 10 Kd subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_941_0027"
                     /evalue="3.50E-29"
                     /label="ctg1_941"
                     /locus_tag="ctg1_941"
                     /protein_end="93"
                     /protein_start="2"
                     /score="100.8"
                     /tool="antismash"
                     /translation="VVPIGDKVVVKRMTREEKTSGGIVLPGAAQEKSQEGRVLSVGDGR
                     LLADGTRAAVQVSEGDRVVLSPWAGTEIKVADEELLIVSEEDILAV"
     CDS             3520..4887
                     /locus_tag="ctg1_942"
                     /transl_table=11
                     /translation="VTNDNLENDSFDDGADENQPILRIDGSHRRGKRGAPKSVEVPPAD
                     AVLIVSPEELPTEEVSQEVLSYIAGRDPAAVQSQLDEQAIQLASHMAARLKELDRREAT
                     LNARIAQLETEVRLSRLADRERVMATAEREKEIEQREQILHDLEHDFARRDSALREQEG
                     THQASGIDASALAQREDQLRARRQDLDRAASNFHHAQLLWDREKATQEQAAADKLAAER
                     AALELEYAARHKRLDEVELQLLAQTQQVASELRSLSDERATWNVERERQLRAIEKRSAV
                     AEEQLARKTKAIATRETMLDEQQRSLLTLQDQLHTMHRETLEMRLIAEQLWAQTSGRLS
                     TPEVMQSIAALRLKLAEHYQIDLAQVAKEREELSRLATRLAEQARALDSRHQELKTWRS
                     REQQAVEHDARQLLAQQIELEEQSSRLAAERATWQEERRRLLAEIRELRKAELTSV"
     CDS             5001..5978
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_943"
                     /sec_met_domain="DUF692 (E-value: 2.4e-87, bitscore: 290.6,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSSSDNSLPRLPRLGLPNLGLGVGLRSSHFGYLLREQPAVDWLE
                     VLSENYLDSQGRPRAVVRTLAEHYPLVLHGVSLSIGSTDPLNFGYLEKLRALAAETEAR
                     WVSDHLCWTGVMGRNSHDLLPLPLTETCLAHVAARVHAVQEFLGRPIVLENPSSYITFA
                     QSTLGEAEFLATLSQQTGCGLLLDLNNVLVSCINHGWDPIEYLDTIPADRVVQMHLAGH
                     TKLATHLLDTHDGPVIDPVWQLFAYATQKTGAVSTLLEWDAKIPEFPVVHAEVLRAKSM
                     IEQYLNQSADSIRASCREYASREASEPQSLAIPHPSTLATAEVE"
     PFAM_domain     5061..5843
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_943_0028"
                     /evalue="3.10E-103"
                     /label="ctg1_943"
                     /locus_tag="ctg1_943"
                     /protein_end="281"
                     /protein_start="20"
                     /score="344.7"
                     /tool="antismash"
                     /translation="GLGVGLRSSHFGYLLREQPAVDWLEVLSENYLDSQGRPRAVVRTL
                     AEHYPLVLHGVSLSIGSTDPLNFGYLEKLRALAAETEARWVSDHLCWTGVMGRNSHDLL
                     PLPLTETCLAHVAARVHAVQEFLGRPIVLENPSSYITFAQSTLGEAEFLATLSQQTGCG
                     LLLDLNNVLVSCINHGWDPIEYLDTIPADRVVQMHLAGHTKLATHLLDTHDGPVIDPVW
                     QLFAYATQKTGAVSTLLEWDAKIPEFPVVHAEVLRAKSM"
     CDS             5982..6878
                     /locus_tag="ctg1_944"
                     /transl_table=11
                     /translation="VNRRELPLETLQQWMLTAIAHPGGIRAGLDAAQRATGIHAEHLSS
                     LISPSQWQSSAERLAVYNDAYFARLLACMVELFPATAELLGLEAFQALAARYLVTHPPT
                     SYSLHHLPDTFEAHLQSRLPDDDPLAICVLDMLRLERAIDRVFDGPGLEEQTLVPLHEK
                     LASVQLDELLASRLVLHPSLQILELRSAVSHFYTQFRKQQRRELPAIFNAPESLALIRR
                     HYIVQRVPLSPAEHLLIRAAQQHPLVSELLEHLGELAESQQRDHKLAETALAELRPIMA
                     RLAETGVFCDLHFQQRD"
     PFAM_domain     6012..6338
                     /aSDomain="DUF2063"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09836.11"
                     /description="Putative DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_944_0029"
                     /evalue="4.90E-19"
                     /label="ctg1_944"
                     /locus_tag="ctg1_944"
                     /protein_end="119"
                     /protein_start="10"
                     /score="68.5"
                     /tool="antismash"
                     /translation="LQQWMLTAIAHPGGIRAGLDAAQRATGIHAEHLSSLISPSQWQSS
                     AERLAVYNDAYFARLLACMVELFPATAELLGLEAFQALAARYLVTHPPTSYSLHHLPDT
                     FEAHL"
     CDS             7038..7769
                     /locus_tag="ctg1_945"
                     /transl_table=11
                     /translation="MTKKSSAPKSPTKNPPQKQVLLLSCMDLRLADDTARFMDAYNLQN
                     RYDHLTFAGAAMGALHLGTPIEQSNRSMVTLPWKKVFFHHFQVAIEVLRREIKDVFLVE
                     HFDCGAYKNLHPSADVRREYERLSRMDMKLLEPIHAEEAAAFADEIKEFCDERQAFHGT
                     VLVAIQTLITVGSNAPSEVKKLFRQVFEPESTCPIEKWKVPAAELLYRKLIETELKVAA
                     WKDIGVRAYVLDLKGNPIDLF"
     CDS             7986..8198
                     /locus_tag="ctg1_946"
                     /transl_table=11
                     /translation="VIAFDVSVNGRVIQTVGAGEKGMIRTELMWACFTRHIGRRLELIA
                     TLFSWDEWGRVGALVMGHVALQTWR"
     CDS             8582..9352
                     /locus_tag="ctg1_947"
                     /transl_table=11
                     /translation="VSADTLVAELVEAGVHFGHRASRWNPKMAPYIYARKNGIHIVDIR
                     ETVRGLLRAKKYLAQVAAQGSLILFVGTKKQAGPAIEREALRCHMPFVAERWLGGTLTN
                     FRTIRSRLGRLEEVEKVRGGEELATYSKKAQSALAREYRKMYRNLNGIRTLNRLPECLV
                     IFDPNKEKNAIKEARSLGIKTVALIDTDCDPDTVDLPIPGNDDGIRSVELIARHLAEAI
                     LVGAQSAASRKGDKGDRPAPAAPAPDKDADGASA"
     aSDomain        8600..9259
                     /aSDomain="TIGR01011"
                     /aSTool="tigrfam"
                     /description="rpsB_bact: ribosomal protein uS2"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_947_0004"
                     /evalue="3.50E-83"
                     /identifier="TIGR01011"
                     /label="ctg1_947"
                     /locus_tag="ctg1_947"
                     /protein_end="226"
                     /protein_start="6"
                     /score="276.2"
                     /tool="antismash"
                     /translation="VAELVEAGVHFGHRASRWNPKMAPYIYARKNGIHIVDIRETVRGL
                     LRAKKYLAQVAAQGSLILFVGTKKQAGPAIEREALRCHMPFVAERWLGGTLTNFRTIRS
                     RLGRLEEVEKVRGGEELATYSKKAQSALAREYRKMYRNLNGIRTLNRLPECLVIFDPNK
                     EKNAIKEARSLGIKTVALIDTDCDPDTVDLPIPGNDDGIRSVELIARHLAEAILVGA"
     PFAM_domain     8609..9253
                     /aSDomain="Ribosomal_S2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00318.22"
                     /description="Ribosomal protein S2"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_947_0030"
                     /evalue="1.60E-83"
                     /label="ctg1_947"
                     /locus_tag="ctg1_947"
                     /protein_end="224"
                     /protein_start="9"
                     /score="279.3"
                     /tool="antismash"
                     /translation="LVEAGVHFGHRASRWNPKMAPYIYARKNGIHIVDIRETVRGLLRA
                     KKYLAQVAAQGSLILFVGTKKQAGPAIEREALRCHMPFVAERWLGGTLTNFRTIRSRLG
                     RLEEVEKVRGGEELATYSKKAQSALAREYRKMYRNLNGIRTLNRLPECLVIFDPNKEKN
                     AIKEARSLGIKTVALIDTDCDPDTVDLPIPGNDDGIRSVELIARHLAEAILV"
     aSDomain        9802..10626
                     /aSDomain="TIGR00116"
                     /aSTool="tigrfam"
                     /description="tsf: translation elongation factor Ts"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_948_0005"
                     /evalue="1.10E-57"
                     /identifier="TIGR00116"
                     /label="ctg1_948"
                     /locus_tag="ctg1_948"
                     /protein_end="275"
                     /protein_start="0"
                     /score="193.4"
                     /tool="antismash"
                     /translation="MAEITAALVRALRDETGLPMMDCKKALSESGGDVAAAKEWLRKNG
                     VAILIKRSDRETGFGRFGIYCGVANTTGAIVELKCESAPVAGSEEFITLANDLAKQLAT
                     GPGAKTADELLDQPSPSQPGKTLREVKDEMFNRIREVFNVGRMARFDGPCGGYSHNSGT
                     VSGVLLEVEGGNDVAAKDVCMHTAAMRPISLVKEEIDPAIVEKEREILKAAALNEGKPA
                     NIVDKMVEGRLKNFYAEKCLAEQPFVKENSISVAKYAEQNNMKLKRFVLWELG"
     CDS             9802..10635
                     /locus_tag="ctg1_948"
                     /transl_table=11
                     /translation="MAEITAALVRALRDETGLPMMDCKKALSESGGDVAAAKEWLRKNG
                     VAILIKRSDRETGFGRFGIYCGVANTTGAIVELKCESAPVAGSEEFITLANDLAKQLAT
                     GPGAKTADELLDQPSPSQPGKTLREVKDEMFNRIREVFNVGRMARFDGPCGGYSHNSGT
                     VSGVLLEVEGGNDVAAKDVCMHTAAMRPISLVKEEIDPAIVEKEREILKAAALNEGKPA
                     NIVDKMVEGRLKNFYAEKCLAEQPFVKENSISVAKYAEQNNMKLKRFVLWELGKE"
     PFAM_domain     10018..10629
                     /aSDomain="EF_TS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00889.21"
                     /description="Elongation factor TS"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_948_0031"
                     /evalue="4.30E-45"
                     /label="ctg1_948"
                     /locus_tag="ctg1_948"
                     /protein_end="276"
                     /protein_start="72"
                     /score="154.0"
                     /tool="antismash"
                     /translation="GAIVELKCESAPVAGSEEFITLANDLAKQLATGPGAKTADELLDQ
                     PSPSQPGKTLREVKDEMFNRIREVFNVGRMARFDGPCGGYSHNSGTVSGVLLEVEGGND
                     VAAKDVCMHTAAMRPISLVKEEIDPAIVEKEREILKAAALNEGKPANIVDKMVEGRLKN
                     FYAEKCLAEQPFVKENSISVAKYAEQNNMKLKRFVLWELGK"
ORIGIN
        1 cttcggccct ctcgatcgcg tttcgggaag tggtgggaac gacaccgagc gactatcgat
       61 cgcaagccgg attggcgtag cacaagccag cctccaggcg caccactaag ggacagcaag
      121 tggctgatcc cagcgcgctt tatagaggcg ctcgtcgggg agttcgatct tttcaagcgg
      181 atcgagcagc tgcaagctat tgctccacca attgttgctg gtcagatcgg cttgctgcag
      241 gacaaaccgt ttggattcgc gatgttgatc gatcgatttc actttttttg cttcgggaaa
      301 aagctcgaag ggggcgaagg tttgcgattt caaatccagg gtgtgaatct ttgatgccga
      361 ggtgatcagc agcgatttgc ctccggcggt tggagataca tcgtgcccgt ctccttcggg
      421 aagctgccac gttttttcga ccacaatctc aagcgttggg agcgctgtct tgtcggtcgc
      481 agcggaggtt ttgagggaga cgagcaaaag ttcttcactt ccgagagcat agagcttacc
      541 cccgtcgaca tcccaccagg tgccatgggc gccgacgagt ttcgttcgcg cgatgggagt
      601 tgtgctcgca gggtcgctgt aggagaagat caacagttcg tcgccgccaa agctactggc
      661 gacggcgatt cgtttctcgg gcaacaggca agcgctgtgg gcattgcgtg cggaggcaac
      721 ataaatcgct cgtttggtgt cgcgctcgac caaggctacg ccaccggaag aggacgtgat
      781 gaggatccac ttgtcgtacg gtttgcattc gtcggtcgta cggaactgag catgctgcga
      841 ctggggaatc tctggcgaac tggcggcggt ccagctccaa agtttatcac tctcgccgag
      901 cttgccaggg gtagcgggga tgatgaaaac ctcatccatg ccgcagcaaa tcaggctggg
      961 tggagcggcg gaggccaagg aggtcgcgag cagcagcgcg aagaaaacaa cgaatcgcat
     1021 gacaggcccc aagagcgcga gtgaggtggg atggcctgta gttagaacgt agttctgcgg
     1081 ggaattcaac gctcgggaac gatgagcgtt ggctaaatcg agctgtgatt agcgacgcgc
     1141 agcaacaatc taatcctgaa gcaagcgatg aaaaaacctg gcgcttcatt agcgagagca
     1201 gctgatgcgc tgctctcgcg agggatctct cgaggaactc acgtgtagag ctcgaaaggg
     1261 gacgacctag cgactacttt gtcgctggct tggagtgggc gagtgccaaa agggcatagc
     1321 cggtgacgag cgaagcatcc ccttccatcc agcgcgggtc ggcgttgacg aacgagccat
     1381 cttcggcctg acgcgaggcg agttcagcga tcagctcgct gcgccagttg tgctcgacac
     1441 ccttctcgtc gacgaacgta tcgttgccgg ttgcttcgag cgctttggca aaggtttggt
     1501 agtagtagaa gagccccgac gttcccatgc ctgggttgct gtcgagatcg tagttctttt
     1561 tgagccagcc gatggcagct ttcacgcgca catcgtcggg accgacacca gcatagatca
     1621 tgctcttgag accagcgtag gtcatcgatg catagctgcg aagcgcgccg gtttcggtgg
     1681 taccagcttg gctcacacca ccagcggctg gcgagtagta gaaaccgccg tcgggattct
     1741 tggcagcgta gggagtggtg ttgtgctcgg actcgaggtt ttggcaacgc gaaacgaaga
     1801 ttagagcacg cttcatttct tcgctgttag ggtcggtgcc ggtcgccttc agagcgtcga
     1861 gcaaaaagct ggtattcgag agatcggggc gtttgttttt accgtaacca gcgccgccga
     1921 attcggggtc agcagcggtt tttccttcct tgtcgtccca ctgcagacct ttcacaaagg
     1981 cgtcggcctt cttcacgatg gtgtcgaagc gaccatcttt gttggctgca gcgaagcaaa
     2041 cgacaccgag gcacgtttcg tagttcttgt ggttcgattc cggggcgtag atgccgccat
     2101 cttcctgaac gaactgctgc aagtacttca gagccttggc aaccgcagga tcgtcgaccg
     2161 tgcggccatg cttcagcagc gaagcagtca ccagcgcggt gacggcgggg ccggcagccg
     2221 agttgtacga gccatcggcg gcttgggctt tggtagtgag gtaggtgacc gctttgctga
     2281 cggtttgctg ataaacagcg gcatcgtcgg ctgcggtggc cagcgaggca caggcgatcg
     2341 aggccaaggc aacgaacgag gccagggtgc gacaaatcga tttcatagac gaaaactcca
     2401 agcagcagcg gagatgggtg tgtccagcag gcacgtgcgt tggcataagg ctacgcaaga
     2461 ccgacgcaag gaacaccgat gccatccgcg aggcagatgc agatgagtct tcgattattc
     2521 catgcccgca gcgcgagagg aagagattag gggcgaggag ccgagaagta atgcagcaga
     2581 agcttgggcc aggaagcagc gctgctaagt tcctagaacc gccccaggtc caagggggcg
     2641 cactggtgtg aacagcggcg gcccatgagg ggagtctata gttcagacga ttgagcgacg
     2701 caaagcgttg tcgctcctag atttccgcac gatggatcga gcagagcttc ggccgtgtcc
     2761 tagtcgagta cggcgaggat gtcttcttcg ctgacgatca ggagttcttc gtcagccacc
     2821 ttgatttccg taccggccca aggtgagagg acaacgcggt ccccttccga cacttgcaca
     2881 gctgcccggg tgccatcggc cagcaggcgg ccatcgccga cgctcagcac gcgcccttcc
     2941 tgcgattttt cttgggccgc tccaggcagc acgatgccgc cgctcgtctt ttcttcacga
     3001 gtcattcgtt tcacaaccac tttgtcgcca atcggaacca cgcgcatggc acgaacatcc
     3061 cctctagggt ggtagcagtg caagctttcg tctcgctgct gggtggaaca gactccgccc
     3121 gtgcgatccc caagccagcc gtcgattgtg actaccaccc cggccgactg caagcatcaa
     3181 gtttgctagc agagactgga gatcggtcgt cgctaaggtc gctgacaatt cccttcgcaa
     3241 caaacggcat cgaaactgaa cttggttctc tccattgccg ataaccgagg tgacaaactt
     3301 tgcggcctgg gacaactttg ccggcaactc tgtgggtcaa aacgatcggg tggagctagg
     3361 aaatgcgcct caagcggttt tcacaacccc cacacgagcg ttcttgatgc gtccacactg
     3421 cttctgctgg catgccatcc cgccgctcat cggttgctga tgacgagcgc gtggctggcg
     3481 atttgccggc cagcgacgcg ctcccaggag ggtgagaacg tgacgaacga caacttggag
     3541 aacgacagct tcgatgacgg agctgacgaa aaccagccga tcctgcggat cgatggctcg
     3601 caccgccgtg gcaaacgggg agccccgaag agcgtcgagg tgcctcctgc tgatgccgtg
     3661 ctgatcgttt cgcccgagga acttccgacc gaggaggtgt cgcaagaggt cctgtcgtac
     3721 attgccggac gcgacccagc cgctgtgcag tcgcagctcg acgagcaggc gattcaactg
     3781 gcctcgcata tggccgctcg gctgaaagag ctcgatcgac gcgaggcgac cctcaacgcg
     3841 cggattgcgc agctcgaaac cgaggtgcga ttgtcgcgac tcgccgatcg tgagcgggtg
     3901 atggcaactg ccgagcgcga aaaagagatc gagcagcgcg aacagattct gcatgatctg
     3961 gaacacgatt tcgcccgccg cgatagcgcc ctgcgcgagc aagaaggaac gcaccaagcg
     4021 agcggaatcg atgcttcggc cctggcccag cgcgaagatc agctccgtgc tcgtcgccaa
     4081 gacttagacc gcgccgcttc gaattttcac catgcccagc ttttgtggga tcgcgaaaaa
     4141 gcgacgcagg agcaagcagc cgccgacaaa ctggccgcag agcgggccgc tctcgaactc
     4201 gagtatgccg cgcgtcacaa gcgactcgac gaggtggaac tgcagcttct cgcccaaacc
     4261 cagcaagtgg ccagcgaact gcgctcgctc agcgacgaac gtgccacctg gaatgtcgag
     4321 cgcgagcggc aactgcgtgc catcgaaaag cgatcggcag tcgccgagga gcagctggcg
     4381 cgaaaaacca aggccatcgc cacgcgcgag acgatgctcg acgagcagca gcggagcctg
     4441 cttacgctgc aagatcaact ccacacgatg caccgcgaaa cgttggaaat gcggctgatt
     4501 gccgagcaac tctgggccca aacgagtggt cggctctcga cgccggaagt gatgcaatcg
     4561 atcgccgcac ttcggctcaa actggccgag cattatcaga tcgacctggc gcaagtggcc
     4621 aaagagcgcg aagagctttc gcgcctcgcc acgcgacttg ccgaacaagc gcgtgccctg
     4681 gattcgcgtc atcaggagct caaaacctgg cgcagccgcg agcagcaagc ggtggagcac
     4741 gacgcgcgac aactcctcgc gcagcaaatc gagctcgaag agcaatcgag tcgtctcgca
     4801 gccgagcgtg ctacgtggca agaggagcgc cggcgactac tcgccgagat ccgcgaactc
     4861 cgtaaagcgg aactgacgag cgtataagcg tggcctctcg aagcgaccgc tgcgccgcac
     4921 gaccggatgt cgatccgcta agatgcaaat aagccagcag catctttcgg tcgcatcgtt
     4981 cgcttactaa acgccgcgct atgtcctctt cgtccgacaa ttcgctcccc cgcttgccgc
     5041 gcctcggtct ccccaacttg gggctgggcg ttgggctgcg gagctcgcat tttggctacc
     5101 tactgcgcga gcaaccagca gtcgattggc tcgaggtact gagcgaaaac tacctcgatt
     5161 cgcaaggtcg cccccgcgcg gtggttcgca cactagccga gcactatccg ctggtgctgc
     5221 atggcgtttc tctctcgatt ggcagcaccg atccgctgaa ctttgggtat ctcgaaaagc
     5281 ttcgcgcgct ggccgccgaa accgaggccc gctgggtgag cgatcacttg tgctggaccg
     5341 gtgtgatggg gcgcaattcg cacgatctgc ttcccctccc cctcaccgaa acttgcctcg
     5401 cgcatgtcgc cgcgcgcgtc catgcggtgc aagagttctt gggtaggccg atcgttctcg
     5461 aaaaccctag ctcttacatc accttcgcgc aatccacgtt aggtgaagca gagttcctgg
     5521 ctaccctctc ccagcaaacg ggctgtggtc tattattaga tcttaataac gtcttggtct
     5581 cttgcatcaa tcatggatgg gaccccattg agtatttaga taccattcca gccgatcgcg
     5641 ttgtgcagat gcatttggcg ggacatacta aactcgccac gcacttatta gatacccacg
     5701 atggtccggt aatcgatccc gtttggcagc tctttgccta tgcgactcaa aaaaccggag
     5761 ccgttagtac cctactggaa tgggacgcta aaattccaga gtttcccgtc gtgcatgcgg
     5821 aagtgctgcg ggcgaaatcg atgatcgagc agtacctcaa tcagtcggcg gatagcattc
     5881 gcgcgagttg ccgtgaatat gccagtcgcg aggcttctga gcctcaatcg ctggcgattc
     5941 cacacccttc gacactcgct accgcagaag tggagtaggc tgtgaatcgt cgcgaattac
     6001 cgctggaaac cttacagcaa tggatgctca cggctattgc gcacccaggt ggaatccgcg
     6061 cgggtcttga tgctgcgcag cgcgcgacgg gcattcatgc cgaacatcta agctccttga
     6121 tttcgcccag ccagtggcaa tcttccgccg agcgactggc ggtttataac gacgcctatt
     6181 ttgcgcgtct tttggcttgt atggtcgagc tctttcccgc cacagccgag cttttaggtc
     6241 tcgaagcctt tcaagccctt gcagcgcgct atttagtcac ccatccacct accagttatt
     6301 cattgcatca tctgcccgat acctttgaag cccacttaca atcgcgcttg cccgacgatg
     6361 atccgctcgc gatctgcgtg ctcgatatgc tgcggctgga gcgcgccatc gaccgggtgt
     6421 ttgatggtcc gggtctggaa gagcaaacgc tcgtgccgct gcacgaaaaa cttgcctcgg
     6481 tgcagctcga tgagctgctg gccagccgac tcgtgctcca tccgagctta cagattctcg
     6541 agctgcgctc ggcggtgagt cacttttaca cccagtttcg caagcaacag cgtcgcgagc
     6601 tgcctgcgat cttcaacgcg ccggaatcgc tcgccctgat tcgccgccac tacattgtgc
     6661 agcgggttcc cctctctcca gccgagcatc tgctgattcg cgcggcacag cagcatccgc
     6721 tggtgagcga actactcgag catctagggg aactggccga gtcgcagcag cgcgaccaca
     6781 agctggccga gacggccctc gccgagctcc gcccgatcat ggcgcggctg gctgaaacgg
     6841 gcgttttttg cgatcttcac ttccagcagc gcgattaatg accttcgatc catcgaaaat
     6901 ctcgatagta agcatcgaaa gattttcagt aatcgccgcc tcttgcgcgc tgataatagc
     6961 taggccttag cgctacccgt gcgcacttgc gtcgccgcaa gctctgctga gcatcgacac
     7021 ccccgaagga tggattgatg acgaaaaaga gttccgctcc gaagagtccc accaagaatc
     7081 caccccaaaa gcaagttctg ctgctgtcgt gcatggacct gcgactcgcc gacgacactg
     7141 cccgctttat ggacgcctat aatcttcaaa accgctacga ccatctaact ttcgctggcg
     7201 cagcaatggg agcgcttcat ctgggcacac caatcgagca gtccaatcga tccatggtca
     7261 ctttgccttg gaagaaggtc ttcttccacc attttcaagt ggccattgaa gttttaaggc
     7321 gagaaatcaa agatgtattt ctagtcgagc attttgactg tggcgcctat aagaacttgc
     7381 atcccagtgc agacgttcgc cgtgagtacg agcgcctgag tcggatggat atgaagctgc
     7441 tagaacccat ccatgccgaa gaggccgccg cattcgccga cgaaataaaa gagttctgtg
     7501 atgaacgcca agcttttcat ggtacagtgt tagtcgctat tcaaacccta atcacggtgg
     7561 gaagcaacgc tcccagcgaa gtaaagaagt tgtttcgcca agtgtttgag ccagaatcga
     7621 catgcccgat cgaaaaatgg aaggttccgg cagctgagtt gctataccga aaactcattg
     7681 agaccgagct gaaggttgct gcatggaaag atattggcgt gcgagcttat gttctcgatc
     7741 ttaagggtaa tcctatcgat ctgttttaat agtgaaatac attcgcaggc tatcggtctg
     7801 tcgttttatc atgctgctcg ggagtatagg tttctcgagc cgaagatttc gcgaggccca
     7861 ggcaatccat gccgatgaag ccgctaagcg aagataagct ttgtattatt gtgctcaaac
     7921 ggtgttttag tagtggatag ttacttagtg atctcagaac tcttcgcacc aaaaaggaga
     7981 ttctagtgat tgctttcgat gtgtcggtga atggtcgtgt gattcagacc gttggtgcag
     8041 gtgaaaaggg catgatcaga accgaactga tgtgggcttg tttcaccaga cacatcggga
     8101 ggcgattgga gttaattgca actctcttct cgtgggatga atggggaagg gtcggcgcac
     8161 ttgtcatggg acacgtggca ttgcagacct ggcgatgaag tgacgattcg aattgttgag
     8221 cgcgatgcgg ttgatccccc agacgaaact acgccggcga aacctcgacc agggggcgga
     8281 tgaagtgcct tcggtggttg ctgcagttgt cctaacccct tacggggcgc tgggttgacg
     8341 acttttaggg tggccgctag attatgggat tcctcagggc tattcgtgcg cgtttccagg
     8401 ccgaatatgc cgtgggtgat cagccgagcg gctgatcgta aactgttatc tggaaaccat
     8461 ttatcccgct ccaagcgaag gctcttaaga cctgtgacgt aaacggctcg agacacttgc
     8521 ccctgggcaa atggctccgc cagtcatggc tactagggtg tgggaaagaa agaggacact
     8581 cgtgtcggca gatacgctcg ttgcagaatt ggtggaagct ggcgttcact tcggtcaccg
     8641 cgcaagccgc tggaatccga agatggcccc ttacatctat gcccgtaaga acggcattca
     8701 catcgttgat atccgcgaaa ccgttcgcgg tttgctccgt gccaagaagt acctggcgca
     8761 agtcgctgcc caaggcagct tgatcctgtt cgtcggcacc aaaaagcaag cggggcccgc
     8821 gatcgaacgc gaagcactcc gctgccacat gccattcgtt gctgaacgtt ggctcggtgg
     8881 cacgctcacc aacttccgca cgattcgcag ccgactcggt cgtctcgaag aagtcgagaa
     8941 ggtgcgtggc ggtgaagagc tcgccaccta cagcaagaag gcccaatcgg ccctcgctcg
     9001 cgaatatcgc aagatgtatc gcaacctcaa cggtattcgc acgctgaacc gcttgccaga
     9061 atgcctggtg atcttcgatc cgaacaaaga aaagaacgcg atcaaggaag cccgctcgct
     9121 cggcatcaag accgtggctc tgatcgatac cgactgcgat cctgacaccg ttgacctgcc
     9181 aattccaggt aacgacgacg gtatccgctc ggtggaactg atcgctcgcc acttggctga
     9241 agcgatcctg gtgggtgctc agtcggccgc ttcccgcaag ggtgacaagg gcgatcgtcc
     9301 agctccagct gccccagctc ccgacaagga tgccgacggc gcttcggcct aagtgatttc
     9361 gcggccattc gggcctcggt ttcacccggc taccagcgtt tgcggattcc ccgctccacg
     9421 aacattgcta cgtggctcca ctttttgctt cggcgaagtg gagccctgcg agcaaccaat
     9481 cgagagtggc gaggctcgca cacagctcct tgcagcggtt ggccctcttg gcttaagtcg
     9541 ctcggcaaag gcccatgaac ttcaaagttc actggcttgt cgatgcttaa gtaggagtca
     9601 gccgatctcc ttcatgaatt tttgcggcgc aggttccttt cgcaggtcgc gccgcgtcga
     9661 agtgctcgcc aaaatcgcta aaatgcggtc gcgacgagct tcttccccca caacatccac
     9721 ttgctactgc gaagttccag cgccacttgg cgaccacttc cagagcccac gcaatacacc
     9781 acatttcagg agaaattaga gatggccgag attacagccg ccctcgtgcg tgccctgcgc
     9841 gacgagaccg gacttccgat gatggattgc aagaaagccc ttagcgaatc gggtggcgac
     9901 gttgccgctg cgaaggaatg gctccgcaag aacggcgtgg cgattctgat caagcgttcg
     9961 gatcgcgaaa ccggctttgg tcgtttcggc atctactgcg gcgtggccaa caccaccggc
    10021 gcgatcgtcg aactgaagtg cgaaagcgcc ccagtcgctg gcagcgaaga gttcatcact
    10081 ctggccaacg acctggccaa gcaactcgct accggtcctg gtgcaaagac cgccgacgaa
    10141 ctcctcgatc agccttcgcc aagccaacct ggcaagaccc ttcgcgaagt caaagacgag
    10201 atgttcaacc gcatccgcga agtcttcaac gtgggtcgca tggctcgctt cgatggccct
    10261 tgcggtggct atagccataa cagcggtacc gtttcgggcg tactgctcga agtggaaggt
    10321 ggcaacgacg tggctgccaa agacgtctgc atgcacactg ctgcgatgcg tccgatttcg
    10381 ctcgtgaagg aagaaatcga ccccgctatc gtcgagaagg aacgggaaat cctgaaggct
    10441 gctgccctga acgaagggaa gcctgccaac attgtcgaca agatggtgga aggtcgcctg
    10501 aagaacttct acgccgagaa gtgcctcgcc gaacagccgt tcgtcaagga aaacagcatc
    10561 tcggtcgcca agtacgccga acagaacaac atgaagctga agcgcttcgt gctgtgggaa
    10621 ctcggcaagg aataagcccg ccaggtctgt ccccttggga ccgcctgata atcacgctac
    10681 gcttaagccc acggctctgg caccctgcct cagccgtggg ctttttcttt gacttctgtt
    10741 tcgggcgatg gcaaccttcg aaggaatttc gcgatgacgt cggctgcaga gcaaacgact
    10801 cgtcccacgt tcaaacgcgt ggtactcaaa ctctccggcg aaagcctcag tcacgcaggc
    10861 gagcgtggca tcggcatgga agaagtcgtt cacatcgcct cgcaaattca gcaagcgcag
    10921 caactcggct gtcagatcgc ggtggtggtt ggcgggggga atatcctccg gggagccc
//
