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Overview
1.1
1.2
1.3

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP028251.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | T3PKS | 523,198 | 564,355 | 12-epi-hapalindole J isonitrile / ambiguine A isonitrile / ambiguine B isonitrile / ambiguine C isonitrile / ambiguine D isonitrile / ambiguine E isonitrile / ambiguine K isonitrile / ambiguine L isonitrile / ambiguine I isonitrile / ambiguine J isonitrile | Terpene + Alkaloid | 6%
Region 1.2 | RiPP-like | 1,622,626 | 1,634,773 |
Region 1.3 | betalactone | 1,730,154 | 1,762,279 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1.1 | T3PKS | 523,198 | 564,355 | 12-epi-hapalindole J isonitrile / ambiguine A isonitrile / ambiguine B isonitrile / ambiguine C isonitrile / ambiguine D isonitrile / ambiguine E isonitrile / ambiguine K isonitrile / ambiguine L isonitrile / ambiguine I isonitrile / ambiguine J isonitrile | Terpene + Alkaloid | 6%
Region 1.2 | RiPP-like | 1,622,626 | 1,634,773 |
Region 1.3 | betalactone | 1,730,154 | 1,762,279 |

No secondary metabolite regions were found in these records:
  NZ_CP028252.1
  NZ_CP028253.1

Compact view
NZ_CP028251.1 - Region 1 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 523,198 - 564,355 nt. (total: 41,158 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000286.1 |  | 0.23 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0002031.1 |  | 0.17 | Alkaloid | kitasetaline | Kitasatospora setae KM-6054
BGC0001120.1 |  | 0.16 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001664.1 |  | 0.16 | Terpene | merosterol | Scytonema sp. PCC 10023
BGC0000205.1 |  | 0.16 | Polyketide | bryostatin | Candidatus Endobugula sertula
BGC0001104.1 |  | 0.16 | NRP, Polyketide | myxovirescin A1 | Myxococcus xanthus DK 1622
BGC0000922.1 |  | 0.15 | Other | pseudomonas quinolone signal (PQS) | Pseudomonas aeruginosa PAO1
BGC0000880.1 |  | 0.15 | Other (Nucleoside) | tunicamycin B1 | Streptomyces chartreusis NRRL 3882
BGC0001617.1 |  | 0.15 | Terpene | hirsutene | Stereum hirsutum FP-91666 SS1
BGC0001914.1 |  | 0.15 | Other | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000286.1 |  | 0.56 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0002031.1 |  | 0.48 | Alkaloid | kitasetaline | Kitasatospora setae KM-6054
BGC0001120.1 |  | 0.47 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001664.1 |  | 0.47 | Terpene | merosterol | Scytonema sp. PCC 10023
BGC0000205.1 |  | 0.47 | Polyketide | bryostatin | Candidatus Endobugula sertula
BGC0001104.1 |  | 0.46 | NRP, Polyketide | myxovirescin A1 | Myxococcus xanthus DK 1622
BGC0000922.1 |  | 0.46 | Other | pseudomonas quinolone signal (PQS) | Pseudomonas aeruginosa PAO1
BGC0000880.1 |  | 0.46 | Other (Nucleoside) | tunicamycin B1 | Streptomyces chartreusis NRRL 3882
BGC0001617.1 |  | 0.45 | Terpene | hirsutene | Stereum hirsutum FP-91666 SS1
BGC0001914.1 |  | 0.45 | Other | benzastatin J, 7-hydroxyl benzastatin B, 7-hydroxyl O-demethylbenzastatin A, JBIR-67, 7-hydroxyl benzastatin F, 7-hydroxyl O-demethylbenzastatin D, O-demethylvirantmycin, 7-hydroxyl benzastatin D, virantmycin, benzastatin K, methylbenzastatin K | Streptomyces sp. RI18

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP028251.1 - Region 2 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,622,626 - 1,634,773 nt. (total: 12,148 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000617.1 |  | 0.21 | RiPP | coagulin | Bacillus coagulans
BGC0001862.1 |  | 0.16 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.16 | RiPP | pallidocin | Aeribacillus pallidus
BGC0001388.1 |  | 0.16 | RiPP | gassericin E | Lactobacillus gasseri
BGC0000619.1 |  | 0.16 | RiPP | gassericin T | Lactobacillus gasseri
BGC0001602.1 |  | 0.16 | RiPP | gassericin-T | Lactobacillus gasseri
BGC0001863.1 |  | 0.16 | RiPP, Terpene | bacillicn CER074 | Bacillus mycoides
BGC0001861.1 |  | 0.16 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1
BGC0000558.1 |  | 0.15 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000584.1 |  | 0.14 | RiPP | colicin V | Escherichia coli

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000617.1 |  | 0.54 | RiPP | coagulin | Bacillus coagulans
BGC0001862.1 |  | 0.46 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.46 | RiPP | pallidocin | Aeribacillus pallidus
BGC0001388.1 |  | 0.46 | RiPP | gassericin E | Lactobacillus gasseri
BGC0000619.1 |  | 0.46 | RiPP | gassericin T | Lactobacillus gasseri
BGC0001602.1 |  | 0.46 | RiPP | gassericin-T | Lactobacillus gasseri
BGC0001863.1 |  | 0.46 | RiPP, Terpene | bacillicn CER074 | Bacillus mycoides
BGC0001861.1 |  | 0.46 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1
BGC0000558.1 |  | 0.46 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0000584.1 |  | 0.44 | RiPP | colicin V | Escherichia coli

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_CP028251.1 - Region 3 - betalactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,730,154 - 1,762,279 nt. (total: 32,126 nt) Show pHMM detection rules used
betalactone: (HMGL-like and AMP-binding)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | betalactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000904.1 |  | 0.20 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0000649.1 |  | 0.20 | Terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001475.1 |  | 0.17 | Polyketide | aspterric acid | Aspergillus terreus NIH2624
BGC0001441.1 |  | 0.16 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000843.1 |  | 0.16 | Other (Non-NRP beta-lactam) | alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate | Streptomyces clavuligerus ATCC 27064
BGC0000515.1 |  | 0.16 | RiPP | geobacillin I | Geobacillus thermodenitrificans NG80-2
BGC0001391.1 |  | 0.15 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0001909.1 |  | 0.15 | Polyketide | strobilurin | Strobilurus tenacellus
BGC0000506.1 |  | 0.15 | RiPP | entianin | Bacillus subtilis subsp. spizizenii
BGC0001789.1 |  | 0.15 | RiPP | suicin 90-1330 | Streptococcus suis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000904.1 |  | 0.53 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0000649.1 |  | 0.52 | Terpene | carotenoid | Streptomyces griseus subsp. griseus NBRC 13350
BGC0001475.1 |  | 0.49 | Polyketide | aspterric acid | Aspergillus terreus NIH2624
BGC0001441.1 |  | 0.47 | Other | belactosin A, belactosin C | Streptomyces sp.
BGC0000843.1 |  | 0.46 | Other (Non-NRP beta-lactam) | alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate | Streptomyces clavuligerus ATCC 27064
BGC0000515.1 |  | 0.46 | RiPP | geobacillin I | Geobacillus thermodenitrificans NG80-2
BGC0001391.1 |  | 0.46 | RiPP | thusin | Bacillus thuringiensis serovar rongseni
BGC0001909.1 |  | 0.46 | Polyketide | strobilurin | Strobilurus tenacellus
BGC0000506.1 |  | 0.46 | RiPP | entianin | Bacillus subtilis subsp. spizizenii
BGC0001789.1 |  | 0.46 | RiPP | suicin 90-1330 | Streptococcus suis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names