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Overview
1.1
1.2
1.3

### Identified secondary metabolite regions using strictness 'relaxed'

NC_018631.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | RiPP-like | 27,928 | 42,152 |
Region 2 | arylpolyene | 215,924 | 258,035 | chejuenolide A / chejuenolide B | Polyketide | 7%
Region 3 | T3PKS | 897,148 | 938,308 |

NC_018631.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 27,928 - 42,152 nt. (total: 14,225 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000617.1 |  | 0.31 | RiPP | coagulin | Bacillus coagulans
BGC0001388.1 |  | 0.27 | RiPP | gassericin E | Lactobacillus gasseri
BGC0000619.1 |  | 0.27 | RiPP | gassericin T | Lactobacillus gasseri
BGC0001602.1 |  | 0.27 | RiPP | gassericin-T | Lactobacillus gasseri
BGC0000558.1 |  | 0.23 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0001862.1 |  | 0.21 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.21 | RiPP | pallidocin | Aeribacillus pallidus
BGC0000554.1 |  | 0.21 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001863.1 |  | 0.21 | RiPP, Terpene | bacillicn CER074 | Bacillus mycoides
BGC0001861.1 |  | 0.20 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000617.1 |  | 0.65 | RiPP | coagulin | Bacillus coagulans
BGC0001388.1 |  | 0.61 | RiPP | gassericin E | Lactobacillus gasseri
BGC0000619.1 |  | 0.61 | RiPP | gassericin T | Lactobacillus gasseri
BGC0001602.1 |  | 0.61 | RiPP | gassericin-T | Lactobacillus gasseri
BGC0000558.1 |  | 0.56 | RiPP | sublancin 168 | Bacillus subtilis subsp. subtilis str. 168
BGC0001862.1 |  | 0.53 | RiPP | geocillicin | Aeribacillus pallidus
BGC0001930.1 |  | 0.53 | RiPP | pallidocin | Aeribacillus pallidus
BGC0000554.1 |  | 0.53 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0001863.1 |  | 0.53 | RiPP, Terpene | bacillicn CER074 | Bacillus mycoides
BGC0001861.1 |  | 0.53 | RiPP | bacillicin BAG2O | Bacillus cereus BAG2O-1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_018631.1 - Region 2 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 215,924 - 258,035 nt. (total: 42,112 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001184.1 |  | 0.26 | Other | bacilysin | Bacillus velezensis FZB42
BGC0000888.1 |  | 0.26 | Other | bacilysin | Bacillus sp. CS93
BGC0001538.1 |  | 0.25 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0000938.1 |  | 0.22 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000204.1 |  | 0.21 | Polyketide | benastatin A, benastatin B, BE-43767, TAN1532B | Streptomyces sp. A2991200
BGC0001591.1 |  | 0.21 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.21 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000904.1 |  | 0.20 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001343.1 |  | 0.18 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0001927.1 |  | 0.18 | Other | A-94964 | Streptomyces sp.

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001184.1 |  | 0.59 | Other | bacilysin | Bacillus velezensis FZB42
BGC0000888.1 |  | 0.59 | Other | bacilysin | Bacillus sp. CS93
BGC0001538.1 |  | 0.58 | NRP, Polyketide | caboxamycin | Streptomyces sp. NTK 937
BGC0000938.1 |  | 0.56 | Other (Aminocoumarin) | fosfomycin | Streptomyces fradiae
BGC0000204.1 |  | 0.54 | Polyketide | benastatin A, benastatin B, BE-43767, TAN1532B | Streptomyces sp. A2991200
BGC0001591.1 |  | 0.54 | Other | fatty acid enol ester | uncultured bacterium CSLC2
BGC0001688.1 |  | 0.54 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSLC2
BGC0000904.1 |  | 0.53 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001343.1 |  | 0.50 | Polyketide | aurachin A, aurachin D | Stigmatella aurantiaca Sg a15
BGC0001927.1 |  | 0.49 | Other | A-94964 | Streptomyces sp.

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NC_018631.1 - Region 3 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 897,148 - 938,308 nt. (total: 41,161 nt) Show pHMM detection rules used
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | T3PKS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000286.1 |  | 0.22 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0000255.1 |  | 0.20 | Polyketide | pederin | Uncultured bacterium
BGC0001120.1 |  | 0.17 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001104.1 |  | 0.16 | NRP, Polyketide | myxovirescin A1 | Myxococcus xanthus DK 1622
BGC0000720.1 |  | 0.16 | Saccharide | tobramycin | Streptoalloteichus tenebrarius
BGC0000554.1 |  | 0.16 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000880.1 |  | 0.15 | Other (Nucleoside) | tunicamycin B1 | Streptomyces chartreusis NRRL 3882
BGC0000719.1 |  | 0.15 | Saccharide | tobramycin | Streptoalloteichus hindustanus
BGC0000874.1 |  | 0.15 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0001591.1 |  | 0.14 | Other | fatty acid enol ester | uncultured bacterium CSLC2

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000286.1 |  | 0.55 | Polyketide | viguiepinol | Streptomyces sp. KO-3988
BGC0000255.1 |  | 0.53 | Polyketide | pederin | Uncultured bacterium
BGC0001120.1 |  | 0.48 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001104.1 |  | 0.46 | NRP, Polyketide | myxovirescin A1 | Myxococcus xanthus DK 1622
BGC0000720.1 |  | 0.46 | Saccharide | tobramycin | Streptoalloteichus tenebrarius
BGC0000554.1 |  | 0.46 | RiPP | SRO15-3108 | Streptomyces filamentosus NRRL 15998
BGC0000880.1 |  | 0.46 | Other (Nucleoside) | tunicamycin B1 | Streptomyces chartreusis NRRL 3882
BGC0000719.1 |  | 0.46 | Saccharide | tobramycin | Streptoalloteichus hindustanus
BGC0000874.1 |  | 0.44 | Other | blasticidin S | Streptomyces griseochromogenes
BGC0001591.1 |  | 0.44 | Other | fatty acid enol ester | uncultured bacterium CSLC2

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names