LOCUS       c00008_NZ_CABK..       23890 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_CABKUZ010000008.1 Paenibacillus ihuae isolate MGYG-HGUT-01507,
            whole genome shotgun sequence.
ACCESSION   c00008_NZ_CABK..
VERSION     c00008_NZ_CABK..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:07:44
            Original ID  :: NZ_CABKUZ010000008.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 151005
            Orig. end    :: 174895
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23890
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[161005:164895]"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13890
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     cand_cluster    1..23890
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..23890
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     CDS             204..1040
                     /locus_tag="ctg8_132"
                     /transl_table=11
                     /translation="LNKLIKAASMIVLPLLLMVLAYLAYKNVQALSGPQLDLLKLAPYA
                     VFLTGGVLAWKFNRSREFFQMVIFTLAAASLQYLPKLPGTGAAMALPDLYVILCVLLPV
                     NILIFSFFKERGIFSLWGSIRLGLIAAEAAAAVWAMLPERSALLERLQMELLSVNLQGL
                     TPLSQLSLMIFILTFIRLIIRQMSYRSSQDVAFMAVLLGIFYVLHLDHDPVAYALLWTM
                     SGIILITSIIQDSYAMAFSDELTGLPSRRALKQDMLKLGMNYAIAMLDIDHFKKIQ"
     CDS             994..1440
                     /locus_tag="ctg8_133"
                     /transl_table=11
                     /translation="MRLPCWILTISKKFNDTYGHDTGDEVLKLVASIVKDVTGGGKAFR
                     YGGEEFTILFPGKSIQEAMPHLEELREKVAKRGFTVRGQSRGKGKAKRKSKSRSGGAGK
                     QIYITISIGIAQKNEKSKTPDAVMKAADTALYRAKKKGRNCVSK"
     aSDomain        1027..1245
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg8_133_0001"
                     /evalue="3.20E-17"
                     /identifier="TIGR00254"
                     /label="ctg8_133"
                     /locus_tag="ctg8_133"
                     /protein_end="84"
                     /protein_start="11"
                     /score="60.7"
                     /tool="antismash"
                     /translation="KKFNDTYGHDTGDEVLKLVASIVKDVTGGGKAFRYGGEEFTILFP
                     GKSIQEAMPHLEELREKVAKRGFTVRGQ"
     PFAM_domain     1027..1245
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_133_0001"
                     /evalue="3.80E-14"
                     /label="ctg8_133"
                     /locus_tag="ctg8_133"
                     /protein_end="84"
                     /protein_start="11"
                     /score="52.9"
                     /tool="antismash"
                     /translation="KKFNDTYGHDTGDEVLKLVASIVKDVTGGGKAFRYGGEEFTILFP
                     GKSIQEAMPHLEELREKVAKRGFTVRGQ"
     PFAM_domain     1294..1425
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_133_0002"
                     /evalue="2.40E-09"
                     /label="ctg8_133"
                     /locus_tag="ctg8_133"
                     /protein_end="144"
                     /protein_start="100"
                     /score="37.2"
                     /tool="antismash"
                     /translation="GAGKQIYITISIGIAQKNEKSKTPDAVMKAADTALYRAKKKGRN"
     aSDomain        1297..1431
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg8_133_0002"
                     /evalue="2.10E-10"
                     /identifier="TIGR00254"
                     /label="ctg8_133"
                     /locus_tag="ctg8_133"
                     /protein_end="146"
                     /protein_start="101"
                     /score="38.5"
                     /tool="antismash"
                     /translation="AGKQIYITISIGIAQKNEKSKTPDAVMKAADTALYRAKKKGRNCV
                     "
     CDS             1645..2541
                     /NRPS_PKS="Domain: PKS_KR (56-229). E-value: 1.4e-13.
                     Score: 43.0. Matches aSDomain:
                     nrpspksdomains_ctg8_134_PKS_KR.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     223.5; E-value: 4.8e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_134"
                     /sec_met_domain="adh_short (E-value: 3.4e-33, bitscore:
                     108.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.9e-37, bitscore:
                     122.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQYKIQDPATQYPKATPEYQQQQPAPGLETAMHPKPDDGAETY
                     RGSGRLTGRKAVVTGADSGIGRAVAIAFAREGADVLLAYMPEEEADAREVVKLVEDAGR
                     KAVAMPGDLKDEQYCEQLIAAAVEQLGGIDILANIAGMQQFVPDIADLTTEQFDATFKT
                     NVYSLFWLCKAAIKHMKPGSTIINTSSIQAYTPAPILLDYATTKAAINTFSKSLAQQVA
                     EQGIRVNVVAPGPVWTPLQVSGGQPVEALKDFGAKTPLSRPGQPAEMAPAYVFLASQES
                     SYISGETLNANGGMPTP"
     aSDomain        1813..2331
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_134_PKS_KR.1"
                     /evalue="1.40E-13"
                     /label="ctg8_134_PKS_KR.1"
                     /locus_tag="ctg8_134"
                     /protein_end="229"
                     /protein_start="56"
                     /score="43.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVTGADSGIGRAVAIAFAREGADVLLAYMPEEEADAREVVKLVED
                     AGRKAVAMPGDLKDEQYCEQLIAAAVEQLGGIDILANIAGMQQFVPDIADLTTEQFDAT
                     FKTNVYSLFWLCKAAIKHMKPGSTIINTSSIQAYTPAPILLDYATTKAAINTFSKSLAQ
                     QVAEQGIRVN"
     PFAM_domain     1822..2529
                     /aSDomain="adh_short_C2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13561.8"
                     /description="Enoyl-(Acyl carrier protein) reductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_134_0003"
                     /evalue="2.30E-63"
                     /label="ctg8_134"
                     /locus_tag="ctg8_134"
                     /protein_end="295"
                     /protein_start="59"
                     /score="214.0"
                     /tool="antismash"
                     /translation="GADSGIGRAVAIAFAREGADVLLAYMPEEEADAREVVKLVEDAGR
                     KAVAMPGDLKDEQYCEQLIAAAVEQLGGIDILANIAGMQQFVPDIADLTTEQFDATFKT
                     NVYSLFWLCKAAIKHMKPGSTIINTSSIQAYTPAPILLDYATTKAAINTFSKSLAQQVA
                     EQGIRVNVVAPGPVWTPLQVSGGQPVEALKDFGAKTPLSRPGQPAEMAPAYVFLASQES
                     SYISGETLNANGGM"
     CDS             2657..2965
                     /locus_tag="ctg8_135"
                     /transl_table=11
                     /translation="MGQRANLIIVREQAYELYYSHWCANTLPADLFWGPEYALSFIERQ
                     TRAEESGPGWLNEVWAEGGAVIDLEKRKLLFYGGEDILLDIPLRNLFLRLMGCIWQG"
     CDS             3247..5259
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 87.5; E-value: 1.6e-26)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_136"
                     /transl_table=11
                     /translation="MDGGFAGDDLLLFPLAGELTSYLLNGPAFINRINKSYGYRSLVLS
                     EWTEDFPAAGFHIDVTQKRIEIWHAKDFAAAQTRIQSEWPGWEVIDHCGDYKSQVRRTG
                     GALKLQVADEQQLLDQLQNMLLKDFASNPADSLTYCAQKEAEAGKTVEINPYALKYDTY
                     RLPGERKVELWDSAVSKLRMKKQQLLKGLPEDHGLSSRTLLDFFAQIQQSALAVNTFML
                     LQDGVVTAAFARAPYRLDQPQLLYSLSKSITSIAAGIAIDEGLLTLADTVISFFPAKLP
                     GDISPNLARMTVHHLLSMNAGHHDNIYGAVAQEEDWVRAFLAQDVPHEPGSHYVYSTHC
                     TYMLSAIIEQVSGQSLVDYLQPRLFEPLEIPRPVWETCPLGITAGGMGLSLSTESIAKF
                     GQMLLNKGEYAGKRIVSERYLALATSEQSDNRLSAPKDRTDSAQGYGYQFHLCRRGCYR
                     GDGSFGQLCLVAPREQIVIAVTAAFGSMQQLQTLLDFIYEYIIDQLDRKEAYNHADTLE
                     LQNKLAAWTYPLPPVQPVPSLALYYGRKGYRLDDNPHGLREIVLEIEEKRLTVQLCYGD
                     ERDNVLPFSFTEMLHAQDVFYKDLSLHRQEVITSAAWQNQHTLQLTLLYIETPYIVTYT
                     IGFREEEIDVEFRINVSLNIPEYSTTGVIVLDEGS"
     PFAM_domain     3913..4686
                     /aSDomain="Beta-lactamase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00144.26"
                     /description="Beta-lactamase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_136_0004"
                     /evalue="2.60E-26"
                     /label="ctg8_136"
                     /locus_tag="ctg8_136"
                     /protein_end="480"
                     /protein_start="222"
                     /score="92.7"
                     /tool="antismash"
                     /translation="LQDGVVTAAFARAPYRLDQPQLLYSLSKSITSIAAGIAIDEGLLT
                     LADTVISFFPAKLPGDISPNLARMTVHHLLSMNAGHHDNIYGAVAQEEDWVRAFLAQDV
                     PHEPGSHYVYSTHCTYMLSAIIEQVSGQSLVDYLQPRLFEPLEIPRPVWETCPLGITAG
                     GMGLSLSTESIAKFGQMLLNKGEYAGKRIVSERYLALATSEQSDNRLSAPKDRTDSAQG
                     YGYQFHLCRRGCYRGDGSFGQLCLVAPREQIVIAVT"
     CDS             5356..5541
                     /locus_tag="ctg8_137"
                     /transl_table=11
                     /translation="MPEYSHIQTYIKCDQFNFREVIRHFSEVINSLGLDSRYFNDELEW
                     EVSDNGFMYVGGGAEI"
     CDS             5850..6071
                     /locus_tag="ctg8_138"
                     /transl_table=11
                     /translation="MRDIVVNYGEIKDKILYGDTWTVLVRITRHIEGTWDTYADVAFIV
                     DEAPWELLETGYSFNLWAGKDIAIVTII"
     CDS             6214..6606
                     /locus_tag="ctg8_139"
                     /transl_table=11
                     /translation="MENLPRYYVTNEAINSLNEKLGLPKPDKHSQDWVYEVSNSSRVAG
                     FFSFYENAILNMEEKFALMNLVISSYDDAIAEGKVLPGMWNGIRGQLMKHISMYKDLIS
                     YWALIDEEDFEDGSAITPYMRDLINR"
     CDS             6777..7448
                     /locus_tag="ctg8_140"
                     /transl_table=11
                     /translation="MKKMVAMQIQLEDQTFTLNVQYSKRKKISLHIDGAGRITVKAPKG
                     TTEEVILNAVQGHSGWIMEKLREQAAARQVPKAKEYQEEGSFLYLGKEFPLHELITTGE
                     RDAEALKLELKKFYFASLKKIVAERMPRYQAVLKVKPKSFEIVESRTKWGSCSSDKKLT
                     FNYRLAMAPPEVIDYVIIHELCHLLHMNHDRSFWRRLGSVMPDYKRQEEFLARFGQFMT
                     L"
     PFAM_domain     6852..7421
                     /aSDomain="DUF45"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01863.19"
                     /description="Protein of unknown function DUF45"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_140_0005"
                     /evalue="6.00E-54"
                     /label="ctg8_140"
                     /locus_tag="ctg8_140"
                     /protein_end="215"
                     /protein_start="25"
                     /score="183.3"
                     /tool="antismash"
                     /translation="KKISLHIDGAGRITVKAPKGTTEEVILNAVQGHSGWIMEKLREQA
                     AARQVPKAKEYQEEGSFLYLGKEFPLHELITTGERDAEALKLELKKFYFASLKKIVAER
                     MPRYQAVLKVKPKSFEIVESRTKWGSCSSDKKLTFNYRLAMAPPEVIDYVIIHELCHLL
                     HMNHDRSFWRRLGSVMPDYKRQEEFLA"
     CDS             complement(7503..8501)
                     /locus_tag="ctg8_141"
                     /transl_table=11
                     /translation="MREILGRKLKRDIVSPIGLTIIPAETILSEQHLQLIANHKADRQS
                     IFLYPDKMEHRKNQVNEIVKQSEELFHSIKHTSEIPVKDLTTKLVPQLREFVNNTNVYE
                     LLETLKYQDDYTYRHNIAVGAIATLIGNWLNLDEDELSSLTLAGTMHDVGKLNIPSEIL
                     NKPGKLTVEEFDLIKSHTIIGYDLLKESFGQNSNVSLVALQHHEKGNGKGYPYGIRKSK
                     IHYHSKIVMVADVYHAMSSKRSYHEVIPFYEVINHMRASAYGEMDPKILSVFHTNMIRR
                     LIGQQVELLDGTICKVVYVYPYEQDAIFQLENGTFLDSSKDHQIHIKEVFI"
     PFAM_domain     complement(7785..8156)
                     /aSDomain="HD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01966.24"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_141_0006"
                     /evalue="2.60E-15"
                     /label="ctg8_141"
                     /locus_tag="ctg8_141"
                     /protein_end="239"
                     /protein_start="115"
                     /score="56.8"
                     /tool="antismash"
                     /translation="TYRHNIAVGAIATLIGNWLNLDEDELSSLTLAGTMHDVGKLNIPS
                     EILNKPGKLTVEEFDLIKSHTIIGYDLLKESFGQNSNVSLVALQHHEKGNGKGYPYGIR
                     KSKIHYHSKIVMVADVYHAM"
     CDS             complement(9178..9762)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 131.7;
                     E-value: 4.3e-40)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_142"
                     /transl_table=11
                     /translation="MENAVAHPILLSFPESFESERLLIRAPLWGDGAAVNTAVLESLDE
                     LRPWMPWARLLPTPEQAEATIRKSRLEFLERKDLRLLLLHKTSGEIVGSSGLHRIDWQT
                     RKFEIGYWVRSSYSRQGYITEAVHAITNYAVQELQANRIEIRCDTRNTPSARVAERSGF
                     TLEGILRNDKCDVDGKLRDTMIFAKVRGVEY"
     PFAM_domain     complement(9271..9702)
                     /aSDomain="Acetyltransf_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13302.9"
                     /description="Acetyltransferase (GNAT) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_142_0007"
                     /evalue="1.90E-25"
                     /label="ctg8_142"
                     /locus_tag="ctg8_142"
                     /protein_end="164"
                     /protein_start="20"
                     /score="90.2"
                     /tool="antismash"
                     /translation="RLLIRAPLWGDGAAVNTAVLESLDELRPWMPWARLLPTPEQAEAT
                     IRKSRLEFLERKDLRLLLLHKTSGEIVGSSGLHRIDWQTRKFEIGYWVRSSYSRQGYIT
                     EAVHAITNYAVQELQANRIEIRCDTRNTPSARVAERSGFT"
     CDS             10001..11932
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 192.1; E-value: 2.8e-58)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_143"
                     /sec_met_domain="Asn_synthase (E-value: 3.4e-27, bitscore:
                     89.3, seeds: 78, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 1.5e-17, bitscore:
                     57.1, seeds: 307, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIYHLQQHNLDPEQGPELMKQLNRYPADDARGWQSKSVFL
                     GCRSQWITPQSINEQLPYYDPERKLAITADAIIDNRSELLNILRVPAPDRESIPDSLLI
                     LLAYEKWGEQAPVYLVGDFAFMIWDERQHKLFGARDFSGNRTLYFHRSQSSFTFCTVIH
                     PLLSLAGAGNELNDQWVSEFLAIPNRVDAMDCFSTVYPSIEQLPPSHSISITGGNITFS
                     RYFTLQAPPELRLSSNGEYEEAFREVFGRAVKDRLRTHLAAGANLSGGLDSGSVVSFAA
                     EELRHRGRPLYTFSSYPVDGFAGFNLGKRVADERPYIQETIDYVGNIQPSLLNFPERSP
                     YSEIDEWLDIMEMPYKFIENSYWLKGIYEQAQQKDIGVLLSGQRGNWSISWGPALDYQA
                     KLIREFRWLTFYRENKGYTQSMEANRRKVLQIVGKKAFPSLGRLLPRQQETVPELIDPG
                     FAKRTEVHERLREFNGPVGASSTTVYDIRRKHFEQPHIWNVNGTVATKLSLKYRIWDRD
                     PTNDLRVIRFCLSVPEEQYVQNGVDRSLIRRAMAGRLPDNVRLNRKRRGVQGADGIQRM
                     IPQWGAFLSELREMTQDARAAAYLNSTGLAGCLDRLGSEPAPSLIFNADFRLLTRGLVF
                     YRFLKRLS"
     PFAM_domain     10175..10495
                     /aSDomain="GATase_7"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13537.8"
                     /description="Glutamine amidotransferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_143_0008"
                     /evalue="5.00E-15"
                     /label="ctg8_143"
                     /locus_tag="ctg8_143"
                     /protein_end="165"
                     /protein_start="58"
                     /score="55.6"
                     /tool="antismash"
                     /translation="EQLPYYDPERKLAITADAIIDNRSELLNILRVPAPDRESIPDSLL
                     ILLAYEKWGEQAPVYLVGDFAFMIWDERQHKLFGARDFSGNRTLYFHRSQSSFTFCTVI
                     HPL"
     PFAM_domain     10733..11707
                     /aSDomain="Asn_synthase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00733.23"
                     /description="Asparagine synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_143_0009"
                     /evalue="3.90E-25"
                     /label="ctg8_143"
                     /locus_tag="ctg8_143"
                     /protein_end="569"
                     /protein_start="244"
                     /score="89.3"
                     /tool="antismash"
                     /translation="FREVFGRAVKDRLRTHLAAGANLSGGLDSGSVVSFAAEELRHRGR
                     PLYTFSSYPVDGFAGFNLGKRVADERPYIQETIDYVGNIQPSLLNFPERSPYSEIDEWL
                     DIMEMPYKFIENSYWLKGIYEQAQQKDIGVLLSGQRGNWSISWGPALDYQAKLIREFRW
                     LTFYRENKGYTQSMEANRRKVLQIVGKKAFPSLGRLLPRQQETVPELIDPGFAKRTEVH
                     ERLREFNGPVGASSTTVYDIRRKHFEQPHIWNVNGTVATKLSLKYRIWDRDPTNDLRVI
                     RFCLSVPEEQYVQNGVDRSLIRRAMAGRLPDNVRLNRKRRGVQG"
     CDS             11962..12087
                     /gene_functions="biosynthetic-additional (lassopeptides)
                     predicted lassopeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_144"
                     /transl_table=11
                     /translation="MKKEYSKPALEVLDVKMTMAGPGISIADSFQDDPDEIVHYS"
     CDS_motif       11962..12021
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKKEYSKPALEVLDVKMTMA"
                     /locus_tag="ctg8_144_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       12022..12087
                     /prepeptide="core"
                     /locus_tag="ctg8_144_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-12.40"
                     /molecular_weight="2244.3"
                     /monoisotopic_mass="2243.0"
                     /core_sequence="GPGISIADSFQDDPDEIVHYS"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKKEYSKPALEVLDVKMTMA"
                     /leader_location="[11961:12021](+)"
     CDS             12200..13135
                     /locus_tag="ctg8_145"
                     /transl_table=11
                     /translation="MASTVQGLAYKAFGLQIFSEFPLPELPLTDEPGLIGSVAVIRGEL
                     AERWQAIPKVTPSLGMLGSEVMFEAKDTAIFSIQDGIRITVSPAAGADMDCVRLYILGS
                     CMGVLLMQKKILPLHGSALVLDNKAYALVGRSGAGKSTLASYLMDQGHLLVSDDVIPVM
                     VQEGQPLAVPGYPQQKLWQQSLDYMGMNSSLYRPLFERETKFAVPVHDRFQTEPLPLAG
                     VFELAVSEEEGPVTVQPISGMERFHTLFNHTYQKAMVDRIGIREWHFGMLASFVNRLPM
                     YRLTRPKQGFSAPQQTSLIFDTIKPHMEER"
     CDS             13139..13438
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_146"
                     /sec_met_domain="PF05402 (E-value: 7.6e-20, bitscore: 64.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 4.3e-29,
                     bitscore: 93.8, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTADVSSLQTVLVKRPGNIASDMDGEKVMLNVKNGKYYNLGEVG
                     GEIWSALDEPVSISRIVQVIQETFDVPAETAEQDVFEFVQSLLAEDLVAIDSGS"
     PFAM_domain     13217..13417
                     /aSDomain="PqqD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05402.14"
                     /description="Coenzyme PQQ synthesis protein D (PqqD)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_146_0010"
                     /evalue="1.50E-17"
                     /label="ctg8_146"
                     /locus_tag="ctg8_146"
                     /protein_end="93"
                     /protein_start="26"
                     /score="63.7"
                     /tool="antismash"
                     /translation="EKVMLNVKNGKYYNLGEVGGEIWSALDEPVSISRIVQVIQETFDV
                     PAETAEQDVFEFVQSLLAEDLV"
     CDS             13435..13890
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_147"
                     /sec_met_domain="PF13471 (E-value: 7.5e-27, bitscore: 87.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAMRRFRLLLNDRAVVALLPEALWRLFLARIRLLFPFDKTAPQL
                     GAQSQETAEVSKAADALKIREITRAIRVGSKVTPWKSTCMVRAVAGLKMLEKRGIDSTL
                     YMGVAKDKQGRMIAHAWLRSGSYYVSGDDVMKGFVVVEKFAKVIQAE"
     PFAM_domain     13534..13857
                     /aSDomain="Transglut_core3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13471.8"
                     /description="Transglutaminase-like superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_147_0011"
                     /evalue="4.80E-21"
                     /label="ctg8_147"
                     /locus_tag="ctg8_147"
                     /protein_end="141"
                     /protein_start="33"
                     /score="74.9"
                     /tool="antismash"
                     /translation="LLFPFDKTAPQLGAQSQETAEVSKAADALKIREITRAIRVGSKVT
                     PWKSTCMVRAVAGLKMLEKRGIDSTLYMGVAKDKQGRMIAHAWLRSGSYYVSGDDVMKG
                     FVVV"
     CDS             13904..15703
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 264.8; E-value:
                     2.7e-80)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_148"
                     /transl_table=11
                     /translation="MQAIIYYIRQLQRLSGVKLYLNLLGMVISGLLESSAILLLVPMLG
                     MAGLQLGGTGAVYNLPVLGFISELPQTSALGLVLGAYVLIVLCQNLISRFVAVRNVEIQ
                     QSYSRQLRYEVYSALLRAEWSFFLKKRTSDLINIMTTEMARVLAGISCFLQFLTSLLFT
                     LVQIAFAFWLSPKMTLAVLVCAVLLSLFSRRFIRKAKKLGSRSSLLGQMYLAGISDQLN
                     GIKDIKSNNLEQSRLDWLHEFTGEVKNEQLDYTRLRSNSQLLYKMSSTLLIAVFIFVSF
                     RFLHAEGPNLLLVILVFARLWPTFATLQSLMEQLASVLPSFKQLKQLEEECLKAAEQGT
                     SDGSGMPVEAITLEQSLEARNVHFRYQPQEPQYSLQGVNVTIPANRMTAIVGRSGAGKS
                     TLVDLLMGLMQPESGDILADGKPITGERLLSYRRSIGYVAQDPFLYNATIRDNLTMIKP
                     DASEEELWEAMEFASSADFVRRMPQGLDTLIGDRGIRLSGGERQRLVLARAIIRKPSIL
                     VLDEATSALDTENEKRIQEALDRLKHSVTLIVIAHRLSTIRGADQILVIDQGRVIQQGV
                     FGGLASDKGGMFSRLLSSQEEAM"
     PFAM_domain     14117..14773
                     /aSDomain="ABC_membrane"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00664.25"
                     /description="ABC transporter transmembrane region"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_148_0012"
                     /evalue="1.90E-19"
                     /label="ctg8_148"
                     /locus_tag="ctg8_148"
                     /protein_end="290"
                     /protein_start="71"
                     /score="70.5"
                     /tool="antismash"
                     /translation="TSALGLVLGAYVLIVLCQNLISRFVAVRNVEIQQSYSRQLRYEVY
                     SALLRAEWSFFLKKRTSDLINIMTTEMARVLAGISCFLQFLTSLLFTLVQIAFAFWLSP
                     KMTLAVLVCAVLLSLFSRRFIRKAKKLGSRSSLLGQMYLAGISDQLNGIKDIKSNNLEQ
                     SRLDWLHEFTGEVKNEQLDYTRLRSNSQLLYKMSSTLLIAVFIFVSFRFLHAEGPN"
     PFAM_domain     15026..15475
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_148_0013"
                     /evalue="1.40E-33"
                     /label="ctg8_148"
                     /locus_tag="ctg8_148"
                     /protein_end="524"
                     /protein_start="374"
                     /score="116.4"
                     /tool="antismash"
                     /translation="LQGVNVTIPANRMTAIVGRSGAGKSTLVDLLMGLMQPESGDILAD
                     GKPITGERLLSYRRSIGYVAQDPFLYNATIRDNLTMIKPDASEEELWEAMEFASSADFV
                     RRMPQGLDTLIGDRGIRLSGGERQRLVLARAIIRKPSILVLDEATS"
     CDS             complement(16359..18008)
                     /locus_tag="ctg8_149"
                     /transl_table=11
                     /translation="MTDRYTLDKGSLSKEILLLLAFLTTDSIDELAQRSPERFAEINWE
                     QFVRLTLHHRVYPFIYPKLSRMQNELVPALVSERLQREYRRNTVQMLQLSGEMGRIGGE
                     LAKXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXPQVVCSGRQTEGPPTGTARVILCSPDGQSA"
     PFAM_domain     complement(17688..17888)
                     /aSDomain="NTP_transf_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14907.8"
                     /description="Uncharacterised nucleotidyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_149_0014"
                     /evalue="1.60E-09"
                     /label="ctg8_149"
                     /locus_tag="ctg8_149"
                     /protein_end="107"
                     /protein_start="40"
                     /score="37.8"
                     /tool="antismash"
                     /translation="EINWEQFVRLTLHHRVYPFIYPKLSRMQNELVPALVSERLQREYR
                     RNTVQMLQLSGEMGRIGGELAK"
     CDS             18199..18951
                     /locus_tag="ctg8_150"
                     /transl_table=11
                     /translation="MRTELFLEQIRILLHMHADGLLGGEVMPEDALLGVVPAAKLPDVL
                     TMAMSLNYQRNAYALWQSVAKAYIDESTRWVFDPHAASLSDPVVLQTSLLLHRVALQPN
                     RHPQIWQRVSGGIVRSSTNGDVAGLIDAVQSDIAILKNIMQHTRKSDFPYLSGPKIFNY
                     WLYVMESYAGIVWKSRELITIAPDTHILQASVKLGICSEGVLNGTAEDRHYVAEAWETA
                     LSGSGLAPIDVHTSLWLWSRAGFPPLIA"
     CDS             18990..19907
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_151"
                     /sec_met_domain="APH (E-value: 6.9e-26, bitscore: 84.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTGIEGIPGAETWRMIEPVLKGWSDDRKYYIEAKEGNKLLLRL
                     SAGKTFARKQDEFALIKRFNQLDFPMSQALGFGTFSGTGREEQVYMLLTWVEGVPLEDR
                     LTALAPEEQYKLGMEAGRILKRIHSIPCGHDLTGWETAMQAKMLRRIKEYEDCPYHLED
                     DEQAIHYVKENIGLIHNVEKVWHHGDFHVGNLIYTPEGGIGVIDFNRWDTGDYAEEFYK
                     VQFFDRELSVSFAKGKLDGYFAGSPPDAFWRRQALYVAYSSLFSIKWAIPFGMDEIQGM
                     MTRGRQAFQDYDAFRRYIPRWYTD"
     PFAM_domain     19050..19718
                     /aSDomain="APH"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01636.25"
                     /description="Phosphotransferase enzyme family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_151_0015"
                     /evalue="1.80E-24"
                     /label="ctg8_151"
                     /locus_tag="ctg8_151"
                     /protein_end="243"
                     /protein_start="20"
                     /score="87.0"
                     /tool="antismash"
                     /translation="VLKGWSDDRKYYIEAKEGNKLLLRLSAGKTFARKQDEFALIKRFN
                     QLDFPMSQALGFGTFSGTGREEQVYMLLTWVEGVPLEDRLTALAPEEQYKLGMEAGRIL
                     KRIHSIPCGHDLTGWETAMQAKMLRRIKEYEDCPYHLEDDEQAIHYVKENIGLIHNVEK
                     VWHHGDFHVGNLIYTPEGGIGVIDFNRWDTGDYAEEFYKVQFFDRELSVSFAKGKLDGY
                     F"
     CDS             20030..20461
                     /locus_tag="ctg8_152"
                     /transl_table=11
                     /translation="MKEHISRSADIVGLFCRLQMNTKKDMPVRSSEMGVLIYTEKQEGL
                     VTPLMVSNFFRVSKPSVTAMINSLVRQGYLRKTSSATDGRSYSISLTVLGAELVKSTST
                     EYFRNLERLEEKMGSVDFGRFIQLMQQATEILSVEGGRS"
     PFAM_domain     20138..20257
                     /aSDomain="Fe_dep_repress"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01325.21"
                     /description="Iron dependent repressor, N-terminal DNA
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_152_0016"
                     /evalue="3.40E-06"
                     /label="ctg8_152"
                     /locus_tag="ctg8_152"
                     /protein_end="76"
                     /protein_start="36"
                     /score="27.3"
                     /tool="antismash"
                     /translation="IYTEKQEGLVTPLMVSNFFRVSKPSVTAMINSLVRQGYLR"
     CDS             20458..21312
                     /gene_functions="other (smcogs) SMCOG1199:NmrA family
                     protein (Score: 212.4; E-value: 1.6e-64)"
                     /gene_kind="other"
                     /locus_tag="ctg8_153"
                     /transl_table=11
                     /translation="MSILVTGASGNVGAHVIEELSRMGEQIVAAGTDVHRLRDKFSTQA
                     KCVYLDFTDSSSFDQALEEVDRVFLMRPPHLGKPEDLYPFIDALKARGIRLAAFLSLMG
                     IEKNPIPPHHKIEKYLEAAGIPYAHIRPGFFMQNLSGIHAEEIRGQNQIFIPAGISRTS
                     FIDAADIGLAAAVLLHEPGRYAGTAHTLTGAESLNYYQAAEILSEFTGRRITYARPGLL
                     KYRRYYIRERGLDKAYVNVTVALYLMTRMGTAEAVTNEFQQLTGRAPRSFRDFVAENLQ
                     SFI"
     PFAM_domain     20464..21108
                     /aSDomain="NmrA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05368.15"
                     /description="NmrA-like family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_153_0017"
                     /evalue="6.30E-18"
                     /label="ctg8_153"
                     /locus_tag="ctg8_153"
                     /protein_end="217"
                     /protein_start="2"
                     /score="65.2"
                     /tool="antismash"
                     /translation="ILVTGASGNVGAHVIEELSRMGEQIVAAGTDVHRLRDKFSTQAKC
                     VYLDFTDSSSFDQALEEVDRVFLMRPPHLGKPEDLYPFIDALKARGIRLAAFLSLMGIE
                     KNPIPPHHKIEKYLEAAGIPYAHIRPGFFMQNLSGIHAEEIRGQNQIFIPAGISRTSFI
                     DAADIGLAAAVLLHEPGRYAGTAHTLTGAESLNYYQAAEILSEFTGRRITYA"
     CDS             21430..21879
                     /locus_tag="ctg8_154"
                     /transl_table=11
                     /translation="LYRLNNEELNQELPENYEELKKAAGRSADWRARLAAVEELGNWNH
                     KQVIDILNRLMISDPVYTVQEAAYKKLSAFGEDVKVPSKNKAELFRGISKIVLRIKKSL
                     PRDHSYEEFKEKLKKMRIDVYDAYEGEKGEDFDNWLEKQWISAVK"
     PFAM_domain     21484..21672
                     /aSDomain="HEAT_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13646.8"
                     /description="HEAT repeats"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_154_0018"
                     /evalue="1.20E-08"
                     /label="ctg8_154"
                     /locus_tag="ctg8_154"
                     /protein_end="81"
                     /protein_start="18"
                     /score="35.3"
                     /tool="antismash"
                     /translation="ELKKAAGRSADWRARLAAVEELGNWNHKQVIDILNRLMISDPVYT
                     VQEAAYKKLSAFGEDVKV"
     CDS             21968..22561
                     /locus_tag="ctg8_155"
                     /transl_table=11
                     /translation="MYTHSYAHPISSQFQTYLELSAGFRPDYPASLGTSTKGSAEITDL
                     VPDAPDLLKVIYSHVAGTRSGEEEPSLIEFIPGYRLIHIAEYEQEMQVLAGILEEKGYS
                     GGGQIFPLLTNYGSDFICLYRSDEGNEVICDLLHDYGDLVVMYDSPEKFLETLCEFYKQ
                     EAYFLDEEGYLDCDLVKEGEIGAELNPGAKYWSE"
     CDS             complement(22623..23381)
                     /NRPS_PKS="Domain: AMP-binding (7-149). E-value: 5.9e-35.
                     Score: 112.4. Matches aSDomain:
                     nrpspksdomains_ctg8_156_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     188.6; E-value: 2.6e-57)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_156"
                     /sec_met_domain="AMP-binding (E-value: 2.7e-46, bitscore:
                     151.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTEGLSRYDLSKLRCAVSAGEPLNLEVINTFQHHFDITIRDGY
                     GQTESTLIIAALKDDPIRIGSMGKSIAPGIAEIIDDQGNPVPPGVVGDIAVHLSMPALF
                     QNYYKDPERKANASHGEYFVTGDRARKDEDGYFWFEGRGDDIIISSGYTIGPFEVEEAL
                     MKHDLVKECAVVASPDEIRGSIVKAFVVLKDGKEGSSELIKELQSHVKEMTAPYKYPRK
                     IEFIHDLPKTASGKIRRVELREQEKRASQE"
     PFAM_domain     complement(22674..22910)
                     /aSDomain="AMP-binding_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13193.8"
                     /description="AMP-binding enzyme C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_156_0020"
                     /evalue="1.50E-24"
                     /label="ctg8_156"
                     /locus_tag="ctg8_156"
                     /protein_end="236"
                     /protein_start="157"
                     /score="86.9"
                     /tool="antismash"
                     /translation="EVEEALMKHDLVKECAVVASPDEIRGSIVKAFVVLKDGKEGSSEL
                     IKELQSHVKEMTAPYKYPRKIEFIHDLPKTASGK"
     PFAM_domain     complement(22935..23357)
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg8_156_0019"
                     /evalue="1.20E-31"
                     /label="ctg8_156"
                     /locus_tag="ctg8_156"
                     /protein_end="149"
                     /protein_start="8"
                     /score="109.8"
                     /tool="antismash"
                     /translation="RYDLSKLRCAVSAGEPLNLEVINTFQHHFDITIRDGYGQTESTLI
                     IAALKDDPIRIGSMGKSIAPGIAEIIDDQGNPVPPGVVGDIAVHLSMPALFQNYYKDPE
                     RKANASHGEYFVTGDRARKDEDGYFWFEGRGDDIIIS"
     aSDomain        complement(22935..23360)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_156_AMP-binding.1"
                     /evalue="5.90E-35"
                     /label="ctg8_156_AMP-binding.1"
                     /locus_tag="ctg8_156"
                     /protein_end="149"
                     /protein_start="7"
                     /score="112.4"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="SRYDLSKLRCAVSAGEPLNLEVINTFQHHFDITIRDGYGQTESTL
                     IIAALKDDPIRIGSMGKSIAPGIAEIIDDQGNPVPPGVVGDIAVHLSMPALFQNYYKDP
                     ERKANASHGEYFVTGDRARKDEDGYFWFEGRGDDIIIS"
ORIGIN
        1 gaaatatgtg tttatcgatg gaagcggcaa agctgccggg gatattcaga gtatcaaata
       61 ttttgcactg tctgaatgca atccggtggt cagcggcggc aaggttatct ggtataccaa
      121 cagcaacggg tcccggatgt tttatacgat tcctgtgaag ggatgacgga tagcagacac
      181 cgacacggag gatttaaacc acattgaaca agttaatcaa agcagcttcc atgatcgtgt
      241 tgcccttatt gttaatggta ttggcttatc tggcttataa gaacgtgcag gccttgtccg
      301 gtccgcagct ggatttactg aagctggcac cctacgccgt atttctgacc gggggtgtcc
      361 tcgcctggaa attcaaccgc agccgggagt ttttccagat ggttattttt acgctggctg
      421 cagcttcgct gcagtattta cctaagcttc cgggaacggg tgcagccatg gctttacctg
      481 atctgtacgt tatcctgtgt gtgctgctgc cggtgaatat tcttattttt tccttcttca
      541 aggaacgggg gatattcagc ttatggggat cgatccggct gggattgatt gcggcagagg
      601 cggcggctgc cgtctgggcg atgctcccgg agagaagcgc tctgctggag cggctgcaga
      661 tggagctgct gtctgtgaat ttgcaggggc tgacgccgtt atcacagctg tccctgatga
      721 tcttcatact cacctttatc cggctgataa tccggcaaat gtcttacagg tcttcacagg
      781 atgttgcttt tatggcagtg ctgctgggaa tattctacgt actgcacctg gatcatgatc
      841 cagtcgccta cgccttgctg tggacaatgt caggcatcat tctgatcacc tccattattc
      901 aagattcata tgccatggct ttctccgatg agcttaccgg cctgccttcc agacgggcat
      961 tgaagcagga catgctgaag ctggggatga actatgcgat tgccatgctg gatattgacc
     1021 atttcaaaaa aattcaatga cacctatggc cacgataccg gagacgaggt gctgaagctg
     1081 gtggcttcga ttgttaagga cgtgaccggg ggaggcaaag ccttccgcta tggcggggag
     1141 gagttcacca ttctgttccc gggcaaaagc atccaggagg ctatgccgca tctggaagag
     1201 ctaagagaga aggtcgcgaa gcgcgggttc acagtacgag ggcagagccg gggcaaaggt
     1261 aaggctaaac gcaaatcaaa atcgcgcagc gggggagcag ggaaacaaat ctatatcacg
     1321 atcagcatcg ggattgccca aaagaatgag aaaagcaaaa caccggatgc agtcatgaaa
     1381 gcggcggata ctgccttgta ccgggcaaaa aagaagggca gaaactgcgt cagcaagtag
     1441 ctgcatattt attatcattt cgggaagaga acatacatat gctggagctg tttaagcaca
     1501 actgggccgt cccttcgtaa aggggcggcc cggctttatg tttagcaggc gggattatgg
     1561 ttacataaag agagtcaaag cgtttctaat gttaattgac ccatagtcat taccaaggtg
     1621 gaaatcacag aggaggaatg tacaatgagc gatcaatata agattcagga ccctgcgacc
     1681 caatatccca aagcaacacc ggaatatcag cagcagcagc cagccccggg actggaaacc
     1741 gcgatgcatc cgaagccgga tgacggtgcg gagacctatc gaggcagcgg gcggcttacc
     1801 ggacgcaaag cggttgtcac tggagcagac agcgggattg gccgtgcggt ggcgatagct
     1861 tttgcccgtg aaggggcgga tgtattgctg gcgtatatgc cggaggaaga agccgatgca
     1921 agggaagtag tgaagcttgt ggaggatgcc ggacgtaagg cagttgcgat gccgggtgat
     1981 ctcaaggacg agcagtactg tgagcagctg attgctgccg ctgtggagca gctcggcggg
     2041 atcgatattc tggcgaatat cgcgggcatg cagcaatttg tgccggatat tgctgatctg
     2101 acgacagaac aattcgacgc caccttcaag accaatgtct attcgctgtt ctggctctgc
     2161 aaggcggcga ttaagcatat gaagccgggc agcaccatta tcaatacctc ttccattcag
     2221 gcctatacac ctgcaccgat cctgctggat tatgcaacga ccaaggcagc gattaacacc
     2281 ttcagtaaat cgctcgccca gcaggttgct gaacagggca tccgcgttaa tgtggtggct
     2341 cccgggccgg tatggactcc gctgcaggtg agcggcggcc agccggtgga ggcactgaag
     2401 gatttcggcg ccaaaacgcc actcagccgt cccggccagc cggccgaaat ggctccagcc
     2461 tacgtgttcc tggccagcca ggaatccagc tatatcagcg gcgaaacgct gaatgccaac
     2521 ggcggcatgc cgacgcctta agggaatagc tggaattgtc ccgtgatgat aaactaaata
     2581 taaccagcaa ttcagttggc gcgtgccggt tcctaaccgg tacgcgctgt ttgcttagcg
     2641 ggaggggaag tctggcatgg gacaacgagc aaatctgatt atagtcagag aacaggctta
     2701 tgagttgtat tatagtcact ggtgtgcgaa tactttgccg gctgatttgt tctgggggcc
     2761 ggagtatgct ctgtcgttca tagaaaggca gacccgggcg gaggaatccg gaccgggatg
     2821 gttgaatgag gtgtgggcgg aaggcggcgc agtaatagat ttggagaaaa ggaagctgtt
     2881 attttatggc ggcgaagata ttctcctgga tatcccgctg cgcaaccttt ttttaaggct
     2941 catggggtgt atctggcagg gctaggagat cacttgggcc tatgaaggca tacttgatct
     3001 tgcatcctat gtaggctatc cccaagaagc actgttagcg gaacgtgaag catataccag
     3061 tgatatgact ctggctccct catcaccaag agaatgggtt gacctggttg caagtgtgaa
     3121 atttgccggt gatgacctgc tgttgttccc tttggccgga gagctcacct cttatctgtt
     3181 gaacggtcca gcgttcatta accgcataaa taagtcatat ggttacagaa gtttagtgct
     3241 gagcgaatgg acggaggatt tgccggtgat gacctgctgt tgttcccttt ggccggagag
     3301 ctcacctctt atctgttgaa cggtccagcg ttcattaacc gcataaataa gtcatatggt
     3361 tacagaagtt tagtgctgag cgaatggacg gaggattttc cggctgcagg ctttcatatt
     3421 gacgttactc aaaaaaggat agagatctgg cacgccaaag attttgcggc agctcaaacc
     3481 cggatacagt ctgaatggcc gggctgggag gtcattgatc attgcggcga ttacaaatcg
     3541 caagtcagga gaaccggagg ggctttgaaa ttacaagtcg cagatgagca gcaattgctg
     3601 gatcagctgc agaacatgtt actgaaggat ttcgcatcca atcctgcgga ttcgctcact
     3661 tactgtgcac agaaggaagc agaggcaggg aaaaccgtag aaattaatcc ctatgccttg
     3721 aagtatgata cataccggtt acccggagaa cgaaaagttg agctgtggga ttctgcagtc
     3781 agtaaactcc ggatgaaaaa acagcagttg ttaaaaggat tacccgaaga tcacgggctg
     3841 tcttcccgca cactgctgga cttcttcgcg caaatccaac agtcggctct cgccgtcaac
     3901 accttcatgc tgctgcagga cggggtagtg acggcagcat ttgctcgggc tccttatcgt
     3961 ctggatcagc cgcagctgct atattcctta agcaaaagca tcacctctat cgcggctggt
     4021 attgccatag acgaagggct tttgacgctt gcggacaccg tcatatcctt cttcccggcg
     4081 aaacttccag gggacatttc tccaaatttg gcccggatga cggtacacca tctgctgtcg
     4141 atgaacgcag gccatcacga taacatttat ggcgctgttg cgcaggaaga agactgggtg
     4201 cgggcttttc tggcgcagga cgttccgcat gagccgggaa gtcattatgt atacagcacc
     4261 cactgtactt atatgctgtc ggcgattatt gagcaggtat ccggccagag tctggttgat
     4321 tatctgcagc cgcgtttgtt tgagcctttg gaaatcccaa gacctgtgtg ggaaacctgt
     4381 ccgctgggga tcacggccgg ggggatgggc ctgagcctgt ctaccgaaag tatcgccaaa
     4441 ttcggccaga tgctgctgaa taaaggagag tacgctggaa aaaggatcgt atctgagcgt
     4501 tatcttgcct tagctacctc ggaacagagc gataaccgcc tgtctgcccc gaaagaccgt
     4561 accgattccg cccagggata cggatatcag tttcatctgt gccgcagggg ctgctataga
     4621 ggggacggtt cttttggcca gctgtgcctg gttgctcccc gggaacaaat tgtcatagcg
     4681 gtaacggccg cgttcgggag catgcagcag ctgcagacac tgctagattt catctatgaa
     4741 tatattattg accagttaga ccgcaaggaa gcttacaacc atgcagatac acttgagctg
     4801 caaaacaaat tagccgcttg gacttatcct cttccaccgg ttcagcccgt tccaagtctg
     4861 gctctttatt atggccgcaa aggttaccgc ctggatgaca atcctcacgg gctgagggag
     4921 atcgtattgg agatagagga aaagcggctg acggttcagc tgtgctatgg ggacgagcgg
     4981 gataatgtgc tgccgttcag ttttacagaa atgctgcatg cgcaggatgt tttctacaaa
     5041 gatctgtcac tgcaccggca agaggtaatc acttcggcgg cctggcagaa tcagcacacc
     5101 ctccagctca ccctgttgta catcgagact ccttacattg taacttatac tatcggattc
     5161 cgggaagagg agatcgatgt ggagttccgg atcaatgtgt ccctgaatat tccggagtac
     5221 agcacaactg gcgtaatcgt gctcgacgaa ggttcataaa attaataact agggatctat
     5281 ccagaggata atgcggtgct gagccactcc aatgagtaga atcgtaatat aaatctaacc
     5341 ccaaggggtg ttattatgcc cgaatattct catattcaaa cttatataaa gtgtgatcaa
     5401 ttcaatttca gagaggttat caggcatttt tcagaagtaa taaactcgct gggacttgac
     5461 tctcgatact tcaatgatga gctggaatgg gaagtttcag ataatggttt catgtacgtt
     5521 ggtggcggtg ctgagatttg atactgctat tttacctgta cacctgattg atttatataa
     5581 ggattatcca aaagatatgt tcatttgtaa gaatgatgaa gtgatgtatg ttgcccaaaa
     5641 atccgtagtg ggggacagaa ccttggcagg acattgatta aacaaacgaa ggacgtttgc
     5701 taaatatagc agcggcgatc taggaactaa taattggaat ggacccgaaa taagctgcga
     5761 ggaaggagga ttgctaacgt ggacagaagg ttcattaaag cccatataag ttggaaaaag
     5821 acccaggtaa gtttccggtg aacgagtgga tgcgtgatat agttgtaaac tatggtgaaa
     5881 tcaaggataa aatactttat ggtgatacat ggactgtgct agttaggata acaagacata
     5941 ttgagggtac atgggataca tatgccgatg tggcattcat agttgacgaa gcaccttggg
     6001 aattgcttga gacaggctat agctttaatc tttgggcagg aaaggatatt gcaatagtca
     6061 cgattatcta agggtaagtc taaaatgaag acacttcatg actacactga ctttgtaaga
     6121 gatcaagcaa atagtgaatt ggacgatatt cgatttttat taaatgaaac ttggattaca
     6181 taaaagtgat gtaacaagag actaggtggg attatggaga acttaccacg ttattatgtt
     6241 acgaatgaag caatcaacag tttgaacgag aaattagggt tacctaagcc ggacaaacat
     6301 tcccaagatt gggtatatga agtatctaat tcatctaggg tagctggatt tttttctttt
     6361 tatgaaaatg ccatacttaa catggaagaa aagtttgctc tgatgaacct tgttatttct
     6421 tcttatgatg atgctattgc agagggaaaa gttctacctg ggatgtggaa cggaatcaga
     6481 ggtcaactta tgaagcatat aagtatgtat aaagacctta tttcctactg ggcattaatt
     6541 gatgaagagg atttcgaaga tggttctgca ataactcctt atatgaggga cctaataaat
     6601 cgttagtata ataaaccatt gatctacata ctggagtctg acactttttt tctttgcaca
     6661 aacaatatcg gcagaccgca gcttgagacc tgagcggtct gtttagctgt gtaacacggg
     6721 ctatgtcccc aagattcatg ctatagttag tccaaacagt ttgtttccca attcatatga
     6781 aaaagatggt ggccatgcag attcagctcg aagatcaaac ttttactctc aatgtccaat
     6841 acagtaaacg caaaaaaatt tccctgcaca tagatggagc aggccggatc actgtgaagg
     6901 ctccaaaagg gacaaccgaa gaggttattc tgaatgcagt acagggtcac agcggatgga
     6961 ttatggagaa gctccgtgaa caggccgcgg cccggcaggt acccaaggcg aaggaatatc
     7021 aggaggaggg cagctttctg tacctcggca aggaattccc gctgcatgaa ttgattacaa
     7081 ccggtgagcg ggatgccgag gcgctgaagc tggagctgaa gaagttctat tttgccagcc
     7141 tgaagaaaat agtggcggag cggatgcccc ggtatcaggc cgtgctgaaa gtaaaaccga
     7201 agtcgttcga gatcgtagag tcacggacca agtgggggag ctgcagcagc gataagaagc
     7261 tgaccttcaa ctaccggctt gcgatggctc cacccgaggt tattgattat gtgattatcc
     7321 acgagctgtg ccatctgctg catatgaatc atgaccggtc cttttggcgg cggctcggga
     7381 gtgttatgcc ggattacaaa agacaggaag agtttctggc ccgctttggt cagtttatga
     7441 cgctctgagc tgccaaggac aaaaacaagg ggatccgccg tctgatttcc cttgaaaaat
     7501 tttcaaataa atacttcttt aatatggatt tggtgatctt tgctggaatc gagaaaagtt
     7561 ccattctcca gctgaaaaat agcatcttgc tcataaggat acacatagac aaccttacat
     7621 attgttccat ccaggagttc aacctgttgt ccaatcaggc gtcttatcat attggtatga
     7681 aatacagata aaattttggg atccatttca ccgtaggcac ttgctcgcat gtggtttatc
     7741 acttcataaa agggtattac ttcatggtat gaccgctttg aggacattgc gtggtataca
     7801 tccgctacca taacaatttt gctgtgataa tgtattttac ttttccggat tccgtaggga
     7861 tagcccttcc catttccttt ttcatgatgc tgcaaagcca caagtgaaac attactattt
     7921 tggccaaaac tctcctttaa caggtcatag ccaatgatgg tatggctttt aataaggtcg
     7981 aactcttcca cagtcagctt acctggttta ttgagtatct cgctcgggat gttcagtttt
     8041 ccaacatcat gcattgtccc ggctaaggta agcgaagaaa gttcatcctc atccaggttc
     8101 agccaatttc caataagggt agcgatagct cctacggcga tattgtgacg atatgtatag
     8161 tcatcctgat attttaacgt ttcaagtaac tcataaacat tagtattatt cacaaattca
     8221 cgtaattgag gaactaactt tgtagttaga tccttcacag gaatttctga agtatgtttg
     8281 atggaatgga acaattcttc ggactgtttt acaatttcat taacttgatt ttttctgtgt
     8341 tccattttat ccggataaag gaaaattgat tggcgatccg ctttatggtt ggcaataagt
     8401 tgaagatgtt gttcagataa aatggtttca gcgggtatga tcgtcaagcc aataggggac
     8461 acaatatctc gtttaagttt tcttcccaat atttctcgca taaatctccc tcttcttacg
     8521 gggaacatcg tactcccctg aaacttttat caattcaatc cagctcgtaa aatatcaaat
     8581 gcctgattta gttgacttat attcaattgg aatgggacaa tcagcaagga gtcaatatat
     8641 ccactaacaa atgaaaaata agacattata tacatctcaa ctgggtgatt aagagtttcc
     8701 tcctgtggaa acgtgtgaat aattcgatgt ataactcagg caagggacga gaagaggata
     8761 ttttgttcag atcataattt ttattttaat cctacaaatg gaaaataagg aatctctcaa
     8821 catattttta attaccttgt aatgcaaata acaaacgtga taataacatt tttttgaaac
     8881 aatcaaaagt gaactttttg tgaaatcaac ttttgaagta aatttacaaa aatattatgt
     8941 cataagcata ttggaccccg atcatcgaag caataaatag gatatgtgcc tggcgcatgt
     9001 gtgaaactta taactaaact cgttgttaat ttaatcgatt agaattgacg ttatgaattc
     9061 atcgttatcg taaaattcag atcctctaga gctcataatt gacctcccgg ggattctgtc
     9121 tgaatttttc cttctattat aactgctgcg ttaatacgtc cggacaaaag tactgcatta
     9181 atactccaca ccccgaacct tggcaaaaat catggtatcc cgcagcttgc catccacatc
     9241 acatttgtcg ttccgcagaa taccttccag tgtaaagccg gaacgttcgg caacccgtgc
     9301 gcttggtgta ttgcgtgtgt cgcagcggat ttcaatccgg ttcgcctgca gctcttgaac
     9361 tgcgtagttc gtaatcgcgt ggaccgcctc cgtgatatag ccctgtctgc tgtaagagga
     9421 gcgcacccaa tagccgattt cgaatttccg cgtctgccag tcaatccggt gtaggccgct
     9481 gctgccgacg atttccccgg aggttttgtg taacaggagg agtctaaggt ctttacgctc
     9541 caggaactcc agccgggatt ttcgaatggt ggcttcggct tgttcaggag taggaaggag
     9601 cctggcccaa ggcatccagg gacgcagttc atcaaggctt tccagcaccg ctgtattcac
     9661 agcagccccg tctccccata agggcgcccg tatcaggagc cgctcacttt cgaagctttc
     9721 cggaaaagat aacagaatag gatgggcaac agcattttcc atagaaacag cctcctaaaa
     9781 aatattaaca ataacatatc atgtcaattg cggactgtac atgaagaaaa tctatacgat
     9841 tatttcggcc tgtctatata ccacataagt gcactcaggt caatacgcta aaggataacg
     9901 aaatatactc cttggtgtaa ttcacattca gtagttagcg agttatctta tatagtaaga
     9961 aatgttcttt ataaagaacc aacaggtgga ggccttcata atgagtgcaa tcgccggtat
    10021 ctatcatcta cagcagcata atctggaccc tgagcaggga ccggagttga tgaagcagct
    10081 taaccgttac ccggctgacg atgccagggg ctggcagagt aagagtgttt ttctcggatg
    10141 ccggtcacag tggattacac cacaatctat aaatgagcaa ctgccttact atgatcccga
    10201 gcggaaactg gccattacag ctgatgcgat cattgataat agaagtgaat tattgaatat
    10261 actgcgcgta cccgcgccag acagagaatc tattcccgat agtctgctga tcctgctggc
    10321 ttatgagaag tggggggagc aggcaccggt atatctggtg ggtgattttg catttatgat
    10381 ctgggatgag cggcagcata aattgtttgg ggcaagggat ttctccggca accggacgct
    10441 ttatttccac agatcccaga gcagctttac tttctgcaca gttattcatc cgctgctgtc
    10501 gctggcgggt gcagggaatg agctgaatga tcaatgggtc tctgaatttt tggcgattcc
    10561 gaatagagtg gatgctatgg actgcttctc gacggtgtac ccatcgatcg aacagctccc
    10621 tccttcacat tctatctcta taaccggagg gaacatcacc ttctcccgtt atttcacact
    10681 gcaagctcct ccggaattgc gcctaagctc caacggggaa tatgaagaag cgttccggga
    10741 agtcttcgga cgggcagtga aggaccggct tcgcacccat ctggcagcag gggccaactt
    10801 aagcggaggg ctggattccg gctcggttgt cagcttcgca gctgaagaac tccggcaccg
    10861 cggccggccg ctttatacgt tcagttccta tccagtagac ggctttgccg gattcaatct
    10921 cgggaaaagg gtggctgatg aacgtcccta tattcaggag acgatcgatt atgtaggaaa
    10981 cattcagccc agtctgctga actttcccga acgcagcccg tacagtgaga ttgatgagtg
    11041 gctggatatc atggagatgc cgtataaatt tatcgaaaat tcctactggt tgaagggaat
    11101 ctatgagcag gcacagcaga aggacatcgg cgtgctgctc agcggacaaa gaggcaactg
    11161 gagtatttcc tggggacccg ctctggatta tcaggctaag ctgatccgtg aattccggtg
    11221 gcttaccttt tatcgtgaga acaagggcta tacccagtcc atggaggcga accgccggaa
    11281 ggtgctgcag attgtcggca aaaaagcgtt cccttcacta ggcagactgc tgccccgcca
    11341 gcaggagacg gtgcctgagc tgattgatcc cggcttcgcc aagcggacgg aagtgcatga
    11401 acggctcagg gagttcaatg ggcccgtggg cgcttcttcg acgactgtct atgatatccg
    11461 aagaaaacat ttcgaacagc cgcatatctg gaatgttaac ggaacagtcg ccactaagct
    11521 gtcgcttaaa taccggatat gggaccggga tccgacgaat gatctgcgtg tcatccgttt
    11581 ctgcctgtct gttccggaag aacagtacgt tcagaacggg gtagaccgct cgcttatccg
    11641 ccgtgcgatg gcgggccggt tgccggataa cgtcaggctg aaccgcaagc gccgcggagt
    11701 gcagggggcg gatggtatcc aacggatgat tccgcagtgg ggcgcctttc tgagcgagct
    11761 ccgtgaaatg actcaggacg cccgcgcggc tgcctatttg aatagtaccg ggctcgccgg
    11821 atgtttggac cggctgggta gtgagcccgc accaagcttg atctttaatg cggattttcg
    11881 ccttttgaca cgcggacttg tgttttaccg tttcttgaag cgtctgtctt aatgaagatc
    11941 gcctgaaagg gggtgacaaa tatgaaaaag gaatacagca agcctgcttt ggaagtgctc
    12001 gacgtgaaaa tgactatggc tggaccagga atatctattg ccgactcctt ccaagatgat
    12061 ccggatgaga tcgtacatta ttcctaaaat ttcatggttc gcgcggccct catccccctg
    12121 tgcttgctgg agggggataa gggctatttc catcatccgg cctattccgg gtgacaaatt
    12181 ggcttaggga gggaatctga tggcgagtac tgttcaaggc ctggcttata aagccttcgg
    12241 cctgcaaata ttcagtgaat tccccttgcc cgagcttccc cttacagacg agccgggatt
    12301 gatcggcagc gtggctgtga tccgcggcga gcttgcggag cgctggcagg cgattcccaa
    12361 ggtgactcca agtcttggta tgctgggcag cgaggtgatg ttcgaagcga aggatacggc
    12421 tattttttca attcaggacg ggattaggat tactgtctcg cctgcggctg gagcggatat
    12481 ggactgtgtc cggctgtata ttctggggag ctgcatgggc gtcctgctga tgcagaaaaa
    12541 gattctcccg ctgcatggca gtgcgctggt actcgataac aaagcttatg cgcttgttgg
    12601 acgttcagga gcgggcaaat caacactcgc ctcgtatttg atggatcagg gacatctgct
    12661 ggtcagcgac gacgttattc ccgttatggt gcaagaaggg cagccgcttg cagttccagg
    12721 ttatccgcag cagaagctgt ggcagcagag cctggactat atgggaatga attcgtccct
    12781 ctaccgtccg ctttttgaaa gagaaaccaa gtttgctgtt ccggtgcatg accgcttcca
    12841 gactgagccg ctgccgcttg ccggtgtgtt tgaactggcg gtgtctgaag aggaaggccc
    12901 cgtaaccgtg cagcccatca gcgggatgga gcggttccat acgttattca atcataccta
    12961 ccagaaggcg atggtcgacc ggatcggcat ccgggaatgg cattttggca tgctggcatc
    13021 cttcgtgaac cggctgccga tgtaccggct gacccggccg aaacagggct tcagtgctcc
    13081 gcagcagacc tcgctgattt ttgacacgat taagccacac atggaggaga gataaacgat
    13141 gaatacagca gatgtatcgt cgcttcaaac ggtgctcgtt aagcgtccgg gcaatatcgc
    13201 cagtgatatg gacggggaaa aggtcatgct gaatgtgaag aacggcaaat attacaatct
    13261 gggcgaggtc ggcggagaaa tctggtctgc tttggatgag ccggtctcca ttagccggat
    13321 tgtccaggtt attcaggaaa cattcgatgt tccggcagag acagcagagc aggacgtgtt
    13381 tgaatttgtg caaagcctgc tggctgagga tctggttgcc attgacagcg ggtcatgaca
    13441 gcaatgcggc ggtttcgtct gttgcttaat gaccgggccg ttgtagcgct gcttccggaa
    13501 gccttatggc gtctgttcct cgcgagaatc cggctgctgt tcccgttcga taaaacggcg
    13561 ccccagctcg gggctcagtc gcaggaaact gctgaggtgt ccaaagccgc cgatgcgctg
    13621 aagatccgcg agatcacccg ggccatccgg gtagggagca aagtgactcc ttggaaaagc
    13681 acctgcatgg tcagggcagt ggcaggcctc aaaatgcttg aaaaacgagg gattgacagc
    13741 acactgtaca tgggtgtcgc caaagacaag cagggccgga tgattgctca tgcctggctg
    13801 cgcagcgggt cttattatgt ctccggtgac gatgtgatga agggttttgt tgtagtggag
    13861 aagttcgcga aggtgataca agccgagtga tcgaggtggg ctcatgcaag caataatcta
    13921 ttatatccgg cagcttcagc gcttgtccgg agtgaagctg tatctgaatc tgctgggcat
    13981 ggtgatcagc ggcctgctgg agagctcggc aattctgctg cttgtgccga tgctgggcat
    14041 ggcgggtctg cagctgggcg gaacaggagc tgtgtacaat cttcctgtgc tcgggttcat
    14101 atcggagctg ccgcagacat cagcgcttgg gctggtgctc ggcgcatacg tccttatcgt
    14161 actctgccag aatttaattt cacggtttgt tgcagtccgc aacgtggaga ttcagcagag
    14221 ctacagccgg cagctgcgat atgaagttta tagcgctctg ctgcgggcag agtggtcctt
    14281 tttcctgaag aaacgcacct cagatctgat caatatcatg actacggaga tggcgcgggt
    14341 gcttgccggc atcagctgct tcctgcagtt tcttacctcg ctgctgttca cgctggtaca
    14401 gatcgctttt gccttctggc tgtcgccgaa gatgactctc gcggtattgg tctgtgcggt
    14461 gctgctctcc ttattctccc gcagatttat ccgtaaggcc aagaagctgg gaagccgcag
    14521 ttccctgctc ggccaaatgt atctggccgg aatttccgac cagctgaacg gaatcaagga
    14581 tatcaagagt aacaatctgg agcagtcccg gctggactgg ctgcatgaat ttaccggtga
    14641 ggtgaagaac gaacagctgg attatacacg tctgcgttcg aactcccaat tgctctacaa
    14701 aatgtcgtcc acactgctga tcgcagtgtt catcttcgtt tctttccggt ttctgcatgc
    14761 agaagggccg aatctgctgt tggtcattct cgtatttgcc cggctgtggc cgacttttgc
    14821 cacgctgcag tcgctgatgg aacagctcgc ctccgtgctg ccttccttca agcaattgaa
    14881 gcagctggag gaggaatgtc tgaaggccgc cgaacagggc acttcggatg gaagcgggat
    14941 gccagtggaa gcaatcacct tggaacagag cctggaagcg agaaatgtcc atttccgtta
    15001 tcagccgcag gagccgcagt attcgctgca gggggtcaat gtcactattc cggctaaccg
    15061 gatgacagcc attgtcggac gctcaggtgc tgggaaaagc accttggttg atctgctcat
    15121 gggactgatg cagcccgagt cgggcgacat tcttgccgac ggcaagccga ttacgggaga
    15181 gcggctgctg tcctaccgcc gctcgatcgg ttatgtggcg caggacccgt tcctgtataa
    15241 cgccaccatt cgggataatc tgacgatgat caaaccggat gccagcgagg aagagctgtg
    15301 ggaagcgatg gagtttgcct cttcggccga ctttgtccgc aggatgccgc aggggctgga
    15361 cacgctgatc ggcgaccgcg gcatccgctt gtccggcggt gagcggcagc ggctggtgct
    15421 ggcacgggcg attatccgca agccgtccat cctggtactg gatgaggcga caagtgcgct
    15481 cgataccgag aacgagaagc ggattcagga ggcgctcgac cggctgaagc attccgtcac
    15541 gctgatcgtc atcgcccacc gcttgtccac gatccgcggc gcggatcaga ttctggttat
    15601 cgaccagggc cgcgtgattc agcagggggt cttcggcgga ctcgcctccg acaaaggcgg
    15661 catgttcagc cggctgctca gcagccagga agaggcgatg taacttggta gtaagttagg
    15721 ggcccttgct gtagatcatc tatacaggtt catgcactaa cacaacttaa aacgcacccg
    15781 gtctccacga gcagtgggga tcgggtgcgt ttgtttagtt atatcgtgct tctcaaattc
    15841 tctgcttgtc tgctgctcaa gcgtgatgcg taagttttcg ctaaacgtgc tattcaagct
    15901 ggacatgcgc aggcttcccg ggctgcatcc gcgctaagtg tatttcttgc agttatttcc
    15961 ttgcttttgt aactcttttt gaatttagtt gcacattgta caattggaaa tgccggattg
    16021 ctcatattcc gccgaatgct tacagattag atgtacgaag tgcagctaaa tcctgttttg
    16081 cccggcaatg ttaaattgta gttgtacgag atacagttat tccgccgatc gcgagtaact
    16141 atcaggattc cccccggccg gttaccttcc gccaagccca caggaaaggg cgaagcggga
    16201 agtagagtac atgcagcggc ttcggtagcg gaagagtttt ggcatccgcc gcatacggat
    16261 acaggaagcc ggctacgtac aggaactgat gccacggcgt taggatcgcc ggctgataat
    16321 atttgaagtg ccgctcgact tccggcgcaa gcggcggatt atgcagattg accatccggg
    16381 ctacatagaa taacgcgagc tgtgccagtc ggcgggcctt cggtttgtct gccagagcat
    16441 acaacctggg gtcnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnactt ggcaagctct
    17701 ccgccgatac gccccatttc tccgctgagc tgaagcatct ggaccgtatt tctgcggtat
    17761 tcccgctgta aacgttcgct gaccagcgca ggaacaagtt cattttgcat ccggctaagc
    17821 ttgggatata tgaacggata cacccggtga tgcagcgtaa gccggacaaa ctgctcccag
    17881 ttaatctccg cgaaccgctc cgggctacgc tgtgccagct catcaataga atctgttgtt
    17941 aaaaaggcaa gaagaagcaa tatttcctta gataagctcc ctttatcaag ggtataccgg
    18001 tcagtcatag ggactctcct tactggaatt tagatacgaa tggagcaggt atgttctatt
    18061 taaagaacga atgcacacag agcgtaacat cggcagcaga atgttgtcaa tttcaatata
    18121 gtaatagtta gaaaaaatga tagacgatgg gatataatgg tccaaactgg aacttcattt
    18181 ttttcacccg gagggaatat gcgaactgaa ctatttcttg aacaaatccg gatattgctg
    18241 cacatgcatg ctgacggact tctgggcggg gaagttatgc cggaggatgc gctgcttggg
    18301 gttgttccgg ctgctaagct gccggatgtg ctgacaatgg cgatgtcgct taattatcag
    18361 aggaatgcct atgccctctg gcagtcggtg gccaaagctt atatagatga gagtacccgg
    18421 tgggtttttg atccgcacgc cgcttctcta agtgatccgg ttgtactgca gacatcgctg
    18481 ctgctgcatc gcgtagccct acagcctaac cggcatccgc agatttggca gcgggtttcc
    18541 gggggaattg tccgctcctc cacgaacggc gatgtagccg gtctaatcga tgcggtacag
    18601 tccgacattg caatcctgaa aaatataatg cagcatacac gcaaatctga ttttccctat
    18661 ctgtccggtc cgaaaatttt caattactgg ctgtatgtga tggagagcta tgcggggatt
    18721 gtctggaagt cccgtgagct gattacgatt gctccggata cgcatatttt gcaggccagc
    18781 gtgaagctgg gaatttgctc tgaaggagtg ttaaacggta ctgccgaaga cagacattat
    18841 gtagctgaag catgggagac ggcgcttagt ggttcgggtc tggcgccgat tgatgtacat
    18901 acctcgcttt ggttatggag ccgggccggt tttccgccgc ttatcgcata gggacttaat
    18961 aatcgagttg gatatggagg gtgaaaatca tgacagatac cggcatcgaa ggaataccgg
    19021 gagcagaaac atggcggatg attgagcctg tactcaaggg ctggtcggat gaccgaaagt
    19081 attacataga ggccaaggaa ggtaacaagc tactgctccg gctgtcggcc gggaaaacct
    19141 ttgcccgtaa gcaggatgaa tttgcgctca tcaagcggtt taatcaactg gattttccga
    19201 tgtcacaggc tcttggtttc gggactttca gtgggacagg ccgggaggag caggtgtata
    19261 tgctgctgac ctgggtggag ggagttccgc tggaagaccg tctgactgca cttgcgccgg
    19321 aggaacagta taagctgggg atggaggctg gccgaatttt aaagaggata cacagcatcc
    19381 catgcggcca tgatctgaca ggctgggaaa cggccatgca ggccaagatg ctgaggcgga
    19441 tcaaggaata tgaggattgt ccgtatcatc tggaggacga tgaacaggcc attcattatg
    19501 tgaaagagaa tatcggcctt attcataacg tggagaaagt ctggcaccat ggtgatttcc
    19561 acgtcggcaa tctcatttac accccggagg gcgggatcgg cgttattgac ttcaaccgct
    19621 gggacaccgg tgattatgca gaggagttct ataaagtcca gttctttgac cgggagctga
    19681 gcgtttcctt tgccaagggc aagttggacg gttattttgc aggatcacca ccggacgcct
    19741 tctggcggag acaggcattg tatgtggcct acagctcgct tttttcgatt aaatgggcga
    19801 ttccctttgg catggacgag attcaaggga tgatgacccg cggcaggcag gcatttcagg
    19861 attacgatgc atttcgcagg tacattccgc gctggtatac cgattagaga acattgtgtt
    19921 taaggattgc ccccggactc aggtctgggg gtgtttggca tggattgacg gaagcggaca
    19981 gccatgcgaa aatatagtta atcagactaa ctatattgag gaggagacca tgaaggaaca
    20041 tattagcaga agcgcagata tcgtcggctt attttgccgg ctgcagatga ataccaagaa
    20101 ggatatgcct gtaagatcca gcgagatggg ggtgcttata tatacggaga agcaggaagg
    20161 tcttgtgacc ccgctgatgg taagtaattt tttcagagta tctaagccat ctgtcacggc
    20221 aatgattaat tccctggttc gtcaagggta tctccgcaaa acctcgtcgg ctacagacgg
    20281 cagaagctac agcatttcgc ttaccgtcct tggcgcagaa ctggtgaagt ctacctcaac
    20341 tgagtatttc cgcaatctgg aacggcttga agagaagatg ggcagtgtgg atttcggacg
    20401 gtttatacag ttaatgcagc aggctactga aatattaagt gtggagggcg gccgttcatg
    20461 agtatattgg ttaccggcgc ttcaggaaat gtaggagctc atgtaataga agaattaagc
    20521 agaatgggtg aacagattgt ggcagcaggg acagatgttc acaggctgcg tgacaaattt
    20581 agtactcagg cgaaatgtgt ttatttggat tttaccgata gcagctcctt tgatcaggcc
    20641 cttgaagagg tggacagagt gttcttgatg cgtccgcccc atttaggcaa gccggaggat
    20701 ttgtatccgt ttatagatgc gttgaaggcc cgcgggatcc ggctggctgc tttcctctcg
    20761 ctgatgggga ttgagaagaa tccgattcct ccgcaccaca agattgaaaa atatctggag
    20821 gctgcaggaa taccttatgc ccacatccgt ccgggatttt tcatgcagaa tctatccggt
    20881 attcacgccg aggagatcag ggggcagaac caaatcttta ttccagccgg gatcagccgg
    20941 acaagcttca ttgatgcagc ggatatcgga cttgccgcag cggtattgct ccatgagccc
    21001 ggaaggtacg cgggcactgc ccacacccta acgggagcgg aatctttgaa ctattatcag
    21061 gcggcggaaa tactaagcga gtttaccggc cgcaggatca cctacgccag accgggatta
    21121 ttgaaatacc gcaggtatta tatcagggag cgcgggctgg acaaggcata tgtcaacgta
    21181 actgtggcgc tttacctgat gacgcggatg gggacggctg aagcagtgac taacgaattt
    21241 cagcagctga caggccgggc accacgttcg ttccgggatt ttgttgctga gaacttgcag
    21301 tcttttattt aagcaggacg tcacgtgtag gatgtttttt tcaaggtgta ttaaatttgg
    21361 acaaaagatt gaaatcaggg agcgcaaacg gtagaattgc actaccagca gatttaacca
    21421 agaaggggat tgtatcgttt gaataatgaa gaactgaatc aagagctgcc agagaattat
    21481 gaggagctga agaaggctgc aggccgatct gcggactgga gagcgcgtct tgcggctgtc
    21541 gaagagctgg gtaactggaa ccacaaacaa gtcattgata tcctgaaccg tctgatgatc
    21601 agtgatcctg tatataccgt tcaagaagcc gcgtacaaga agctgagtgc attcggcgaa
    21661 gatgtaaaag ttccgtccaa gaacaaggcc gagctgttca gagggatctc taagatcgtg
    21721 cttcgtatca agaagagcct tccgcgtgac cattcctatg aagagttcaa ggagaagctg
    21781 aagaagatgc ggattgatgt ttacgatgct tacgaaggcg agaagggcga agatttcgac
    21841 aactggctgg agaagcagtg gatttcagcg gttaaatagt ttttcttatg agaagcggat
    21901 cgataaggac tggacaagtt ctgatgggtc cgctttccta atttaatcaa gtaaaggatg
    21961 acaacatatg tatacccatt cctatgcaca cccgatttct tcgcagtttc agacgtatct
    22021 tgagctttcc gccggatttc ggcctgacta tccagccagt ctggggacca gcactaaagg
    22081 cagtgcggaa atcactgatc tggtaccgga tgccccggat cttcttaagg taatctacag
    22141 ccatgttgcc ggaacacgca gcggggaaga ggagccgagt ctgatcgagt tcatccccgg
    22201 ataccgcctc attcatatcg ctgaatatga gcaggaaatg caggtgctgg cgggcattct
    22261 ggaagagaag ggctattccg gcggcggaca gattttcccg ctcctgacga actatggcag
    22321 tgatttcatt tgcctctacc ggtcagacga gggaaatgaa gtaatctgtg atctgctgca
    22381 tgactatggc gatttggttg tgatgtatga ttctcctgag aagttcctgg aaacgctgtg
    22441 tgaattctac aagcaggaag cctatttcct ggatgaggaa ggttatttgg attgcgacct
    22501 ggtcaaagaa ggcgaaatcg gtgcggagct gaatccgggg gcgaagtatt ggtcggaatg
    22561 atatgtcaaa gcccccattc tccacggtga agcggagaat gggggctttt tgctgcccgt
    22621 aactattcct gcgaagcgcg tttttcctgc tcgcgcagct ctacacggcg tattttaccg
    22681 gaggcagtct tcggcagatc atggatgaat tcgatcttgc gcgggtattt gtaaggagca
    22741 gtcatctctt tgacatgact ttgcagctcc ttaatcagct cagaagaacc ttccttgccg
    22801 tccttcagca cgacaaaggc tttgacgatt gatccgcgta tctcatctgg actggctaca
    22861 acggcacatt ccttgacgag atcatgcttc atcagcgctt cttccacttc aaacgggccg
    22921 atggtgtagc ctgagctgat gatgatatcg tcgccccggc cttcgaacca gaaataaccg
    22981 tcctcatcct tgcgcgcccg gtctccggta acgaaatact ccccgtgcga ggcattcgcc
    23041 ttacgttccg ggtctttgta ataattctgg aacagggcag gcatgcttag gtgcactgcg
    23101 atatctccaa ctacacccgg aggaaccgga ttcccctgat catcaatgat ctccgcgatg
    23161 ccgggggcaa tcgatttgcc catggacccg atccggatcg gatcatcctt cagcgcagca
    23221 atgatcagtg tactttccgt ttgcccgtag ccgtcgcgga tcgttatatc gaaatgatgc
    23281 tggaaggtgt tgatgacttc caggttgagc ggttcaccgg cggacacggc gcagcgcagc
    23341 ttggacaggt cataccggga caatccttct gtcttggcca tcaggcggta ttctgtaggc
    23401 gtgcagcata atacctggat gccttgatcc tnnnnnnnnn nnnnnnnnnn nnnnnnncct
    23461 ggatgccttg atcctgcagc agctgcagat aacggtccgg atgaaaagaa ccattataga
    23521 caaaacctgt ggcgccgttg ccgagcaccg tcaggaacgg gctccagatc catttttgcc
    23581 agcccggagc cgctgtagcc catacggtat ccgatttgcg gatgtccagc cattgaggtg
    23641 aaacgatccg caggtgggca taaccccagc catgggtgtg taccacagct ttcgggttgc
    23701 ctgttgtgcc ggaggtatac gccaggatgg cgatatcgtc acggctggtg gccagggccg
    23761 gacgggaatc cggctgtccg tccatcaggc tccccagatc gctccacccg gcttcaagct
    23821 cgtccttgtt tccggatacc gacaggcggt agtcgagggc cggcagatct tccgtgattt
    23881 tattgacttc
//
