GCF_000403725.2_GD7_genomic - 3 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_HG001320.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	terpene	135,174	156,013	carotenoid	Terpene	25%

NZ_HG001323.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 4.1	NAPAA	82,003	115,797
Region 4.2	T1PKS	205,065	249,771	herboxidiene	Polyketide	2%

No secondary metabolite regions were found in these records:: NZ_HG001321.1; NZ_HG001322.1; NZ_HG001324.1; NZ_CAVS020000042 (original name was: NZ_CAVS020000042.1); NZ_CAVS020000043 (original name was: NZ_CAVS020000043.1)

Compact view

NZ_HG001320.1 - Region 1 - terpene

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Location: 135,174 - 156,013 nt. (total: 20,840 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000650.1	0.27	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000648.1	0.24	Terpene	carotenoid	Myxococcus xanthus
BGC0000637.1	0.16	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000640.1	0.16	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000630.1	0.16	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000664.1	0.15	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.1	0.15	Terpene	carotenoid	Streptomyces avermitilis
BGC0000644.1	0.14	Terpene	carotenoid	Dietzia sp. CQ4
BGC0001227.1	0.14	Terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0001456.1	0.13	Terpene	isorenieratene	Streptomyces argillaceus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000650.1	0.61	Terpene	carotenoid	Algoriphagus sp. KK10202C
BGC0000648.1	0.57	Terpene	carotenoid	Myxococcus xanthus
BGC0000637.1	0.46	Terpene	carotenoid	Corynebacterium glutamicum
BGC0000640.1	0.46	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000630.1	0.46	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000664.1	0.45	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0000633.1	0.45	Terpene	carotenoid	Streptomyces avermitilis
BGC0000644.1	0.44	Terpene	carotenoid	Dietzia sp. CQ4
BGC0001227.1	0.43	Terpene	isorenieratene	Streptomyces collinus Tu 365
BGC0001456.1	0.41	Terpene	isorenieratene	Streptomyces argillaceus

Similar known gene clusters

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NZ_HG001323.1 - Region 1 - NAPAA

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Location: 82,003 - 115,797 nt. (total: 33,795 nt) Show pHMM detection rules used

NAPAA: (AMP-binding and PP-binding and TIGR02353)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.21	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001758.1	0.18	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001479.1	0.18	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001844.1	0.18	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001128.1	0.18	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001641.1	0.18	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001900.1	0.18	NRP	fragin	Burkholderia cenocepacia H111
BGC0000375.1	0.18	NRP	indigoidine	Streptomyces chromofuscus
BGC0001135.1	0.18	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.1	0.18	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000427.1	0.53	NRP	shinorine, 4-deoxygadusol, mycosporine glycine	Trichormus variabilis ATCC 29413
BGC0001758.1	0.50	NRP	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0001479.1	0.50	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001844.1	0.50	NRP	holrhizin	Paraburkholderia rhizoxinica HKI 454
BGC0001128.1	0.50	NRP	luminmide	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001641.1	0.50	NRP	kolossin	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001900.1	0.49	NRP	fragin	Burkholderia cenocepacia H111
BGC0000375.1	0.49	NRP	indigoidine	Streptomyces chromofuscus
BGC0001135.1	0.49	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.1	0.49	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061

Similar known gene clusters

No matches found.

Module view

Legend

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 82002 - 115797:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg4_93

Search NORINE for peptide: strict or relaxed

AMP-binding (25..389): X

NRPSPredictor2: (unknown)

SVM prediction details:

Predicted physicochemical class:: hydrophilic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAESIGtVvK
Nearest Stachelhaus code:: lys
Stachelhaus code match:: 80% (moderate)

NZ_HG001323.1 - Region 2 - T1PKS

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Location: 205,065 - 249,771 nt. (total: 44,707 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001909.1	0.32	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000056.1	0.23	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000044.1	0.22	Polyketide	dawenol	Stigmatella aurantiaca DW4/3-1
BGC0001161.1	0.21	Polyketide	1-heptadecene	Moorea bouillonii PNG
BGC0001162.1	0.21	Polyketide	1-heptadecene	Moorea producens JHB
BGC0001163.1	0.21	Polyketide	1-heptadecene	Moorea producens 3L
BGC0000410.1	0.21	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001927.1	0.19	Other	A-94964	Streptomyces sp.
BGC0001458.1	0.19	Other (Aminocoumarin)	salinipostin G	Salinispora tropica CNB-440
BGC0001897.1	0.19	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001909.1	0.65	Polyketide	strobilurin	Strobilurus tenacellus
BGC0000056.1	0.57	Polyketide	esperamicin	Actinomadura verrucosospora
BGC0000044.1	0.54	Polyketide	dawenol	Stigmatella aurantiaca DW4/3-1
BGC0001161.1	0.54	Polyketide	1-heptadecene	Moorea bouillonii PNG
BGC0001162.1	0.54	Polyketide	1-heptadecene	Moorea producens JHB
BGC0001163.1	0.54	Polyketide	1-heptadecene	Moorea producens 3L
BGC0000410.1	0.53	NRP	pseudomonine	Pseudomonas fluorescens
BGC0001927.1	0.52	Other	A-94964	Streptomyces sp.
BGC0001458.1	0.51	Other (Aminocoumarin)	salinipostin G	Salinispora tropica CNB-440
BGC0001897.1	0.51	Polyketide	cepacin A	Burkholderia ambifaria IOP40-10

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 2, location 205064 - 249771:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg4_205

PKS_AT (623..917): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 58.3%

minowa: fatty_acid

Prediction, score:

fatty_acid: 106.1
Methoxymalonyl-CoA: 71.1
Methylmalonyl-CoA: 64.1
Malonyl-CoA: 52.2
Ethylmalonyl-CoA: 44.8
Acetyl-CoA: 39.1
Propionyl-CoA: 36.3
2-Methylbutyryl-CoA: 30.0
Isobutyryl-CoA: 26.8
trans-1,2-CPDA: 24.2
CHC-CoA: 23.5
inactive: 15.1
Benzoyl-CoA: 8.5
3-Methylbutyryl-CoA: 0.0

ctg4_206

CAL_domain (66..517): pk

minowa: Acetyl-CoA

Prediction, score:

Acetyl-CoA: 26.7
AHBA: 18.2
NH2: 17.4
shikimic_acid: 6.9
fatty_acid: 0.0