LOCUS       c00043_NZ_BKAJ..       10921 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_BKAJ01000043.1 Reyranella soli strain NBRC 108950 sequence043,
            whole genome shotgun sequence.
ACCESSION   NZ_BKAJ01000043
VERSION     NZ_BKAJ01000043
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:51:50
            Original ID  :: NZ_BKAJ01000043.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 5933
            Orig. end    :: 16854
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10921
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10933:11854](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5921)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..10921
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10921
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             124..906
                     /locus_tag="ctg43_8"
                     /transl_table=11
                     /translation="VTPQDIARKRILVTNDDGINAPGLEAMIDIATQLSKDVWVVAPEY
                     NQSGAGHSLSLTHPVRARQLSEAKYALEGTPTDCVLFAVKHLLRDHKPDIVLSGVNRGG
                     NMSDDVTYSGTIAGAMEGCLLGIPSIAFSQTYTHPHPVKWDTATQFGADVARRVLDMEI
                     PRNVLINVNFPDVVPSAVKGVRVTRQGVRGFGGHIVERTDPRGGTYYWIAYAPGAHEHD
                     DESDLTSVRSGYVSVTPLHLDLTHEATRHKLAAHFAKD"
     aSDomain        151..858
                     /aSDomain="TIGR00087"
                     /aSTool="tigrfam"
                     /description="surE: 5'/3'-nucleotidase SurE"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg43_8_0001"
                     /evalue="7.40E-68"
                     /identifier="TIGR00087"
                     /label="ctg43_8"
                     /locus_tag="ctg43_8"
                     /protein_end="245"
                     /protein_start="9"
                     /score="226.6"
                     /tool="antismash"
                     /translation="RILVTNDDGINAPGLEAMIDIATQLSKDVWVVAPEYNQSGAGHSL
                     SLTHPVRARQLSEAKYALEGTPTDCVLFAVKHLLRDHKPDIVLSGVNRGGNMSDDVTYS
                     GTIAGAMEGCLLGIPSIAFSQTYTHPHPVKWDTATQFGADVARRVLDMEIPRNVLINVN
                     FPDVVPSAVKGVRVTRQGVRGFGGHIVERTDPRGGTYYWIAYAPGAHEHDDESDLTSVR
                     SGYVSVTPLHLDLT"
     PFAM_domain     154..699
                     /aSDomain="SurE"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01975.19"
                     /description="Survival protein SurE"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg43_8_0001"
                     /evalue="8.60E-59"
                     /label="ctg43_8"
                     /locus_tag="ctg43_8"
                     /protein_end="192"
                     /protein_start="10"
                     /score="198.7"
                     /tool="antismash"
                     /translation="ILVTNDDGINAPGLEAMIDIATQLSKDVWVVAPEYNQSGAGHSLS
                     LTHPVRARQLSEAKYALEGTPTDCVLFAVKHLLRDHKPDIVLSGVNRGGNMSDDVTYSG
                     TIAGAMEGCLLGIPSIAFSQTYTHPHPVKWDTATQFGADVARRVLDMEIPRNVLINVNF
                     PDVVPSAVKGVRVTRQGVR"
     CDS             919..1566
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_9"
                     /sec_met_domain="PCMT (E-value: 1.1e-66, bitscore: 215.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNAPAMQRLIAELRQSGISDERVLAAIAAVDRERFVTPAFAERAW
                     ENTALPIAFGQTISQPLVVAAMTEALNVGPRMKVLEIGTGSGYQAAVLAKLARRVYSVE
                     RFKPLSREAEKLLINLGIYNVVFDVGDGTKGWAGQAPFDRIIVTAAAEERPQALIDQLA
                     VGGILIVPVGRDPTAQVVERIVKSESGLQRDTLMPVRFVPLVAGALPVLGQG"
     PFAM_domain     937..1536
                     /aSDomain="PCMT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01135.21"
                     /description="Protein-L-isoaspartate(D-aspartate)
                     O-methyltransferase (PCMT)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg43_9_0002"
                     /evalue="9.10E-64"
                     /label="ctg43_9"
                     /locus_tag="ctg43_9"
                     /protein_end="206"
                     /protein_start="6"
                     /score="215.2"
                     /tool="antismash"
                     /translation="QRLIAELRQSGISDERVLAAIAAVDRERFVTPAFAERAWENTALP
                     IAFGQTISQPLVVAAMTEALNVGPRMKVLEIGTGSGYQAAVLAKLARRVYSVERFKPLS
                     REAEKLLINLGIYNVVFDVGDGTKGWAGQAPFDRIIVTAAAEERPQALIDQLAVGGILI
                     VPVGRDPTAQVVERIVKSESGLQRDTLMPVRFVPLVA"
     aSDomain        937..1539
                     /aSDomain="TIGR00080"
                     /aSTool="tigrfam"
                     /description="pimt: protein-L-isoaspartate
                     O-methyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg43_9_0002"
                     /evalue="7.10E-69"
                     /identifier="TIGR00080"
                     /label="ctg43_9"
                     /locus_tag="ctg43_9"
                     /protein_end="207"
                     /protein_start="6"
                     /score="229.9"
                     /tool="antismash"
                     /translation="QRLIAELRQSGISDERVLAAIAAVDRERFVTPAFAERAWENTALP
                     IAFGQTISQPLVVAAMTEALNVGPRMKVLEIGTGSGYQAAVLAKLARRVYSVERFKPLS
                     REAEKLLINLGIYNVVFDVGDGTKGWAGQAPFDRIIVTAAAEERPQALIDQLAVGGILI
                     VPVGRDPTAQVVERIVKSESGLQRDTLMPVRFVPLVAG"
     CDS             1667..2734
                     /locus_tag="ctg43_10"
                     /transl_table=11
                     /translation="MPAAAARIHEVPDDLLAAIDYCYDQGWTDGLPVVPPQVDRVHAML
                     AADDRPAETVIAKHPATGLELSLHAAAVNAVMAGCLPAYFPVLVAAFEAMDREPFNFHG
                     STASTGGSAPLVLVSGPIADEIGMNAGVNLFGPGNRPNATIGRATRLILRNVFQMLPGI
                     SDKSTQGNPGKYSLCIAERTRGNPWPPLCQEQGYAAGVSSVTVYAAGGFCNVENHGGNT
                     PEQVLGSVADAMANYGCITLGQSVVILAPEHLQIVAGAGWTRRQAQEFLFTHAKRSVEG
                     MKDVGKFRDREYDAQHGEGAHALAEQGFLHRGLNPDDILITLGGGDAGGHSCFLPSWSR
                     GRGSIMQHAAIRQKK"
     CDS             2744..3022
                     /locus_tag="ctg43_11"
                     /transl_table=11
                     /translation="MQLYAPTSTTATKKRTRAPKLAKLDGARIGILENGKLNAEEMLNE
                     VAQLFVQRHGCTIVKLASKKNASAPAPANTLTQVAPEVDFLITGLGD"
     CDS             3086..3265
                     /locus_tag="ctg43_12"
                     /transl_table=11
                     /translation="VVICTTPFEVTARNIARVLGLPDYPFTKVQHPIGSCTLPELKARA
                     EVAYQQALAILLKE"
     CDS             3293..4204
                     /locus_tag="ctg43_13"
                     /transl_table=11
                     /translation="MQYNGSMKRAPRYPSRWAGWMRTLGTTAALSVALGACSNVFGPKG
                     GTMEYPGSGAGPNAVAVYVVNEKDTVDSISQRYGVSSQTIIDRNKLKGPPYTLKVGQYI
                     ELPGARFVADNTGGATQAAAATSPGPVKRDNLPPPPGSKSEPAEHKTAAGQPTPLSPAA
                     EASKTEATVAATPPPPRMAWPLHGKVLVPYGTQGGQKNDGIDIQAATGDPVKAADGGTV
                     IYAGSDVAHLGNLLLVQHQGGYITAYGNNEALLVKKGDAVKRGQTIAKAGNSGGAASPR
                     LHFEVRRGGSKTVDPMTVLPAQ"
     PFAM_domain     3479..3613
                     /aSDomain="LysM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01476.22"
                     /description="LysM domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg43_13_0003"
                     /evalue="1.80E-08"
                     /label="ctg43_13"
                     /locus_tag="ctg43_13"
                     /protein_end="107"
                     /protein_start="62"
                     /score="34.4"
                     /tool="antismash"
                     /translation="YVVNEKDTVDSISQRYGVSSQTIIDRNKLKGPPYTLKVGQYIELP
                     "
     PFAM_domain     3890..4180
                     /aSDomain="Peptidase_M23"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01551.24"
                     /description="Peptidase family M23"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg43_13_0004"
                     /evalue="2.90E-27"
                     /label="ctg43_13"
                     /locus_tag="ctg43_13"
                     /protein_end="296"
                     /protein_start="199"
                     /score="94.8"
                     /tool="antismash"
                     /translation="KNDGIDIQAATGDPVKAADGGTVIYAGSDVAHLGNLLLVQHQGGY
                     ITAYGNNEALLVKKGDAVKRGQTIAKAGNSGGAASPRLHFEVRRGGSKTVDP"
     CDS             complement(4359..4985)
                     /locus_tag="ctg43_14"
                     /transl_table=11
                     /translation="MSIAEFQRAFADLIASPERCVALREGDADVLAGYDMTPRERKRLE
                     TMVHHEAMSVNCSLYRVNRLIPVYSVLPHSCRLLGDRLMDELDAFWAASRHATLQYRWE
                     SWRFGLWLEERIAKRLLPGGPVEDAIRLEMAMFDVQAAVRGGCGSGGSRRRVVLLRYDP
                     DELLDPTIPAEELQPLASGVTVLIDATGQQLVVRRIDDTLNGKVA"
     CDS             complement(5001..5921)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_15"
                     /sec_met_domain="DUF692 (E-value: 8.3e-54, bitscore: 173.1,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLELTRPEIGHAGIGRPRADQPGVGLLFNGALTDLLGVRPDAVEF
                     LSIIPERFWQDFGRDRSERFAPLPDEVALLDELASRHTLVAHGVGLSIASGSTFDVDHV
                     RQLADWHRRYRFAWISEHLSAVRVQTEVTPDHHAGLALPLAWDRDLLDMLSERVNRVQD
                     ILGTRLLLENGVVHTPVPGSDMSEEDFMNALVRRTGCGLLLDLHNLHVNAVNLGLDADR
                     FINGLDLDAVGEIHVAGGNSLFGAYLDSHAGACPSGVWGLLERTAPRCRNLLGVTFEFH
                     ETYFPGLGDAGVLGQLQQMRAALAA"
     PFAM_domain     complement(5079..5834)
                     /aSDomain="DUF692"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05114.15"
                     /description="Protein of unknown function (DUF692)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg43_15_0005"
                     /evalue="9.00E-57"
                     /label="ctg43_15"
                     /locus_tag="ctg43_15"
                     /protein_end="281"
                     /protein_start="29"
                     /score="192.4"
                     /tool="antismash"
                     /translation="GALTDLLGVRPDAVEFLSIIPERFWQDFGRDRSERFAPLPDEVAL
                     LDELASRHTLVAHGVGLSIASGSTFDVDHVRQLADWHRRYRFAWISEHLSAVRVQTEVT
                     PDHHAGLALPLAWDRDLLDMLSERVNRVQDILGTRLLLENGVVHTPVPGSDMSEEDFMN
                     ALVRRTGCGLLLDLHNLHVNAVNLGLDADRFINGLDLDAVGEIHVAGGNSLFGAYLDSH
                     AGACPSGVWGLLERTAPRCRNLLGVTFEFH"
     misc_feature    complement(5100..5102)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             complement(5935..6180)
                     /locus_tag="ctg43_16"
                     /transl_table=11
                     /translation="MAKERVAEIQLVRDGVQPVLKVTVPKGTTLSDTLKLQPQLSDILG
                     KLKGCLPCNSGVPIWFQEREEIENLVKIDLGTMKRM"
     CDS             complement(6354..6689)
                     /locus_tag="ctg43_17"
                     /transl_table=11
                     /translation="MVMGLTTGLWVSAQVRICDRAFIPATVVRRGDPDAGTVLLKINRF
                     EAGVTVYTQASSMDDGPAWSRGTGPSPVAEAEADAYIARQVARDPDLWVLEIEDHKGQY
                     QLDGKVV"
     PFAM_domain     complement(6372..6677)
                     /aSDomain="DUF1491"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07372.14"
                     /description="Protein of unknown function (DUF1491)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg43_17_0006"
                     /evalue="6.40E-31"
                     /label="ctg43_17"
                     /locus_tag="ctg43_17"
                     /protein_end="106"
                     /protein_start="4"
                     /score="106.9"
                     /tool="antismash"
                     /translation="LTTGLWVSAQVRICDRAFIPATVVRRGDPDAGTVLLKINRFEAGV
                     TVYTQASSMDDGPAWSRGTGPSPVAEAEADAYIARQVARDPDLWVLEIEDHKGQYQL"
     CDS             complement(6701..7633)
                     /locus_tag="ctg43_18"
                     /transl_table=11
                     /translation="MLRAVGEPRRIERAIKRLQGALKGIPSRSVRVTWRGGELRTTIYW
                     ARDDAYWWAVEPRPARDALLLGHAPDAPAKRESITCEINLPRAGADRKVAGIIAADERG
                     TLYLCHSGRMGGSRPGQRKSGFRDFLRDGVWRKLAWPDGEETEALVIAPLDSPRLTRLL
                     GQFVDAVRRFKAGEPPTARTGLCVEPAISDSAMAACDRRLVDVALREELAKRGLFGGAE
                     DLFSLRGERPQPLFALVADGGPEELAMAVGSLSLASARGGPDVRPILVAPAALADPDSD
                     ALQALPFAFVRFRWRGARAVFDGLDDALE"
     CDS             7713..9512
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 127.2; E-value:
                     1.3e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg43_19"
                     /transl_table=11
                     /translation="MAEPPLLALAGIRYHLGDQTILDGVELGIAPGERLSLVGRNGAGK
                     STLLKILAGEPIADSGTRFAQPGATVATLPQEPDFTGHPTVGHYVAAALADALGPSDYR
                     VAALLTEVKLDGAKNPAELSGGEARRAAIARALVAEPDVLLLDEPTNHLDLPTIEWLED
                     KLSAWNGAYVLVSHDRRFLANLSRAVLWLDRGIVRRLDRGYGEFEDWSSAILDREATER
                     HKLDRLIERETEWAGKSIRARRTRNEGRLRALGELRKQRRQQIGPTGRATIEVGTAEQS
                     GALAITARNISKRFGERAIVENFSTRIFRRDRIGLIGPNGAGKTTLLRMLIGELEPDTG
                     SVKLGANLVPVVIDQRRAALDPDRTPWEILADRNDHLLVRGRQMHVMTYLREYLFRDEQ
                     ARQPVRTLSGGERNRLLLAKALAAPSNLLVLDEPTNDLDADTLDLLQEALSDYDGTVLL
                     VSHDRDFLDRLVTSTIAMEGDGTAIEYAGGYSDYVVQRGPRELDAAAPATRREKAPPRE
                     SAPKARLGYKRERALAELPKRIEALHTEIAALNAALTDPDLYRRDAAGFAAKTARLAAA
                     QAELDAAETEWLELELLREELSG"
     PFAM_domain     7776..8165
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg43_19_0007"
                     /evalue="1.90E-24"
                     /label="ctg43_19"
                     /locus_tag="ctg43_19"
                     /protein_end="151"
                     /protein_start="21"
                     /score="86.8"
                     /tool="antismash"
                     /translation="LDGVELGIAPGERLSLVGRNGAGKSTLLKILAGEPIADSGTRFAQ
                     PGATVATLPQEPDFTGHPTVGHYVAAALADALGPSDYRVAALLTEVKLDGAKNPAELSG
                     GEARRAAIARALVAEPDVLLLDEPTN"
     PFAM_domain     8616..9017
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg43_19_0008"
                     /evalue="1.90E-20"
                     /label="ctg43_19"
                     /locus_tag="ctg43_19"
                     /protein_end="435"
                     /protein_start="301"
                     /score="73.9"
                     /tool="antismash"
                     /translation="ENFSTRIFRRDRIGLIGPNGAGKTTLLRMLIGELEPDTGSVKLGA
                     NLVPVVIDQRRAALDPDRTPWEILADRNDHLLVRGRQMHVMTYLREYLFRDEQARQPVR
                     TLSGGERNRLLLAKALAAPSNLLVLDEPTN"
     PFAM_domain     9282..9485
                     /aSDomain="ABC_tran_CTD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF16326.7"
                     /description="ABC transporter C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg43_19_0009"
                     /evalue="2.60E-18"
                     /label="ctg43_19"
                     /locus_tag="ctg43_19"
                     /protein_end="591"
                     /protein_start="523"
                     /score="66.1"
                     /tool="antismash"
                     /translation="LGYKRERALAELPKRIEALHTEIAALNAALTDPDLYRRDAAGFAA
                     KTARLAAAQAELDAAETEWLELE"
     misc_feature    9489..9491
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             complement(9515..9829)
                     /locus_tag="ctg43_20"
                     /transl_table=11
                     /translation="MDRFALEYNLRDACARVAACQQSLVSQRVQVRELERSGLDASVAR
                     ALLDIYEESKSMALFNRDCLAKALTLAQRTTSATAIASNDDATRDEIFLDDDFFYREAA
                     "
ORIGIN
        1 ggtcctggag aactaccaga acgaggacgg ttcggtgacg atccccgagg cgctgcggcc
       61 ctacatgggc gaacttgccg cactgccggc gcctatcagc ggagtagctg ggggcaagcg
      121 caagtgacgc cgcaggacat cgcgcgcaag cgcatcctcg tcaccaacga cgacggcatc
      181 aacgcgcccg gcctggaggc gatgatcgac atcgccaccc agctctcaaa ggacgtctgg
      241 gtggtggcgc ctgagtacaa ccagagcggt gcgggccatt cgctgtcgct cacccatccg
      301 gtgcgcgccc gccagctcag cgaggccaag tatgcgctgg aaggcacgcc gaccgactgc
      361 gtgctgttcg ccgtcaagca cctgcttcgt gaccacaagc ccgacatcgt gctctccggc
      421 gtcaaccgcg gtggcaacat gtccgacgac gtcacctact ccggcacgat cgccggcgcc
      481 atggaaggct gcctgctcgg catcccttcg atcgccttca gccagaccta tacccatccc
      541 catccggtga agtgggatac agccacccag ttcggcgccg acgtggcccg ccgcgtactg
      601 gacatggaga taccgcgcaa cgtcctgatc aacgtcaact tccccgacgt cgtgccgtcg
      661 gccgtcaagg gcgtgcgggt gacgcgccag ggcgtgcgcg gcttcggcgg ccacatcgtc
      721 gagcgcaccg atccgcgcgg cgggacctac tattggatcg cctatgcgcc gggtgcgcat
      781 gagcacgacg acgagagcga cctcacgtcg gtgcgctcgg gctacgtctc ggtgacgccg
      841 ctgcatctcg acctcaccca cgaggcgacg cgccacaagc tcgcggcgca cttcgccaag
      901 gactgagagg ggcaggccgt gaacgccccg gccatgcagc gcctgatcgc cgaattgcgg
      961 cagtcgggca tctcggacga gcgggtgctc gccgccatcg ccgcggtcga ccgcgagcgc
     1021 ttcgtgacgc cggccttcgc cgagcgcgcc tgggagaata cggcgcttcc catcgccttc
     1081 ggccagacca tcagccagcc attggtggtc gccgccatga ccgaggcgct gaatgtcggt
     1141 ccgcgcatga aagtgctcga gatcggcacc ggctcgggct accaggcggc cgtgctcgcc
     1201 aagctggcgc gccgcgtcta cagcgtcgag cgtttcaagc cattgtcgcg cgaagccgag
     1261 aagctcctga tcaatctcgg catctacaac gtcgtgttcg acgtcggcga cggcaccaag
     1321 ggctgggcag gccaggcgcc gttcgaccgc atcatcgtca ccgccgccgc cgaggagcgc
     1381 ccgcaggcgc tgatcgacca gctcgcggtg ggcggcatcc tgatcgtgcc ggtcggccgc
     1441 gatccgaccg cgcaggtcgt cgagcgcatc gtgaaaagcg agagcggtct gcagcgcgat
     1501 acgctgatgc cggtgcggtt cgtcccgttg gtggccggcg cattgccggt gctggggcag
     1561 ggctaacggg agcgcgggcc tctggcccgc tcacgagcgg gccagaggcc cgcgctcctg
     1621 taagacgtgc tacacatacg ctagtcatca acggggggac cacgcgatgc ccgcagcagc
     1681 agcccgcatc catgaggtgc cggacgatct gctcgccgcc atcgactatt gctacgacca
     1741 gggctggacc gacggcctgc cggtcgtgcc gccgcaggtc gatcgcgtgc acgcgatgct
     1801 ggccgccgac gatcgcccgg ccgagaccgt catcgccaag caccccgcga ccgggctcga
     1861 actctccctg cacgccgccg ccgtcaacgc cgtcatggcg ggctgcctgc cggcgtattt
     1921 cccggtgttg gtcgcggcct tcgaggccat ggaccgcgag ccgttcaact tccacggctc
     1981 gactgccagc accggcggct cggccccgct ggtgctggtg agcggtccga tcgccgacga
     2041 gatcggcatg aatgcgggcg tcaacctgtt cggcccgggc aaccggccca acgccacgat
     2101 cggccgggcg acgcggctga tcctgcgcaa cgtcttccag atgctgcccg gcatctccga
     2161 caagtcgacg caaggcaacc caggcaagta cagcctctgc atcgccgagc gtacccgcgg
     2221 caatccctgg ccgccgctct gccaggagca gggttacgcc gcgggcgttt ccagcgtcac
     2281 ggtgtacgcc gccggcggct tctgcaatgt cgagaaccat ggcggcaaca cgccagagca
     2341 ggttctgggc tcggtggccg acgccatggc caactacggc tgcatcacct tgggccagag
     2401 cgtggtgatc ctggcgccgg agcacctgca gatcgtggcc ggcgctggct ggacgcgacg
     2461 gcaggcgcag gagttcctgt tcacccacgc caagcgctcg gtcgagggca tgaaggacgt
     2521 cggcaagttc cgcgaccgcg aatacgacgc gcagcatggc gaaggcgctc atgcgctggc
     2581 cgagcagggc ttcctgcatc gtggcctcaa ccccgacgac atattgatca cgctgggcgg
     2641 cggcgacgcc ggcggccatt catgttttct gccgtcatgg agccgcggcc gcggctcgat
     2701 catgcagcac gccgcgatcc gccaaaagaa gtaggaggaa cctatgcagc tctacgcccc
     2761 cacctcgacc acggccacga aaaagcggac acgcgcgccc aagctcgcca agctcgacgg
     2821 cgcgcgcatc ggcatcctgg agaacggcaa gctcaatgcc gaggagatgc tgaacgaagt
     2881 ggcccagctc ttcgtgcagc gccacggctg caccatcgtg aagctcgcct ccaaaaagaa
     2941 cgcgagcgcc cccgcaccgg ccaacaccct tacgcaggtg gcgccggagg tcgacttctt
     3001 gataaccggc ctgggggatt gagggtcctg ctcgacgtgc agtctgcacg acggcatctc
     3061 cttcgagcag ctcggcaagc gggcggtggt gatctgcacg acacccttcg aggtgacggc
     3121 caggaacatc gcgcgcgtgc tggggctgcc tgactacccc ttcaccaagg tccagcaccc
     3181 gatcggcagc tgcaccctgc ccgagctcaa ggcccgtgcc gaagtcgcct accagcaggc
     3241 cctggcgata ttgctgaagg agtgaataag cccgattccc gccggaatcg tgatgcagta
     3301 caatgggtcc atgaaaagag cccctcgcta cccctcgcga tgggccggct ggatgcgtac
     3361 gctgggtaca acggcggcgc tctcggtcgc gctcggcgcc tgctcgaatg tgttcggccc
     3421 caaaggcggg accatggaat atcccggctc cggcgctggt cccaacgccg ttgccgtcta
     3481 tgtcgtgaac gaaaaagaca cagtcgacag catctcgcag cgctacggcg tgtcctccca
     3541 gaccatcatc gaccgcaaca agctgaaggg tccgccctac acgctgaagg taggccagta
     3601 tatcgagctg cccggcgcca ggttcgtcgc cgacaacacc ggcggcgcca cccaggccgc
     3661 cgcggccacg tcgcccggcc cggtcaagcg cgataacctg ccgccgccgc cgggctccaa
     3721 gagcgagcct gcggagcaca agacggccgc cggccagccg acgccgctca gcccggccgc
     3781 cgaggcgagc aagaccgaag ccaccgttgc ggccaccccg ccgccgccgc gcatggcttg
     3841 gccgctgcac ggcaaggtcc tggtgcccta tggcacccag ggcggccaga agaacgacgg
     3901 catcgacatc caggcggcca ctggagaccc ggtgaaggcg gccgacggcg gcaccgtgat
     3961 ctatgccggc agcgacgtcg cccatctcgg caacctgctg ctggtccagc accagggcgg
     4021 ctacatcacc gcctacggca acaacgaggc gctgctggtc aagaagggcg atgccgtgaa
     4081 gaggggccag accatcgcca aggccggcaa ctccggtggc gctgcgagcc cgcggctgca
     4141 cttcgaggtc cgccgcggcg gcagcaagac cgtcgatccg atgacggtgc tgccggcgca
     4201 gtagcgggtg ctcttgccgg agcgcggacc tccaggtccg ctcttgtcat tctgagcgag
     4261 gcgaaggatc tcatgccggt tgcaagcggc gacgaggtct ttcgcttcgc tcaggacgac
     4321 cgaaatgagc ggacctggag gtccgcgctc cggcaagatc aagccacctt gccgttcagc
     4381 gtgtcgtcga tgcgccggac cacgagctgc tggcctgtcg catcgatcag cacggtgacg
     4441 ccgctcgcca gcggctgcag ctcttcggcc gggatcgtgg gatcgagcag ctcgtcgggg
     4501 tcgtagcgca gcagcacgac ccgccgccgg ctgccaccgc tgccgcagcc gccgcgtacc
     4561 gccgcctgga cgtcgaacat cgccatctcc agccggatcg catcctcgac cggaccaccc
     4621 ggcagcaggc gcttggcgat gcgctcctcc agccacaggc cgaagcgcca agattcccag
     4681 cgatattgca gcgtggcgtg gcgcgacgcc gcccagaagg cgtcgagctc gtccatcagc
     4741 cgatcgccca gcaaccggca ggaatggggc agcaccgagt agaccgggat cagccgattg
     4801 acgcgataga gcgagcagtt aaccgacatc gcctcgtgat ggaccatggt ctcgagccgc
     4861 ttgcgctcgc gcggtgtcat gtcgtagccc gcgagcacgt cggcgtcgcc ctcacgcagg
     4921 gcgacgcagc gctcgggcga ggcgatcagg tcggcaaagg cccgctggaa ttccgcaatc
     4981 gacatggcaa gtccccccct tcaggccgca agcgcggcgc gcatctgttg cagttggccg
     5041 agcacccccg catcgcccag ccccggaaaa taggtttcgt ggaactcgaa ggtcacgcct
     5101 aaaaggttgc ggcagcgcgg cgcggtgcgc tcgagcaggc cccagacgcc ggacgggcag
     5161 gcgccggcat gcgaatcgag ataggcgccg aacaggctgt tgccgccggc gacatggatc
     5221 tcgccgacgg cgtcgagatc gagcccgttg atgaagcggt cggcgtcgag gccgagattg
     5281 acggcgttga catggaggtt gtgcaggtcg agcagcaggc cgcaaccggt gcgccgcacc
     5341 agcgcgttca tgaaatcctc ctcgctcatg tccgagccgg gcaccggcgt gtgcaccacg
     5401 ccgttctcga gcaggagccg cgtgcccagg atgtcctgga cccgattgac gcgctcgctg
     5461 agcatgtcga gcaggtcgcg gtcccaggcc agtggcagcg ccaggccggc atggtgatcg
     5521 ggcgtcacct cggtctgcac ccgcaccgcc gagaggtgct cgctgatcca ggcgaagcgg
     5581 tagcgccgat gccagtcggc gagctgccgg acatggtcga cgtcgaaggt cgagccgctg
     5641 gcgatcgaga ggccgacgcc gtgcgcgacc agcgtgtgac gcgaggcgag ctcgtcgagc
     5701 agcgcgacct cgtcgggcag cggcgcgaag cgctcgctgc gatcgcggcc gaagtcctgc
     5761 cagaaccgct ccgggatgat cgagagaaac tcgacggcat cgggacggac gcccaggagg
     5821 tcggtcagcg cgccgttgaa cagcagtcca acgccaggct gatcggctcg cgggcgtccg
     5881 atcccggcat gcccgatctc gggtcgcgtg agctcgagca tggatgcctc cgcgttacat
     5941 gcgcttcatc gtgccgaggt cgatcttcac caggttctcg atctcctcgc gctcctggaa
     6001 ccagatcgga acgccggaat tgcacggcag gcagcccttg agcttgccga ggatgtccga
     6061 cagctgaggc tgaagcttga gcgtatcgga aagcgtggtt cccttcggca cggtgacctt
     6121 gagaaccggc tgcacgccgt cacgcacgag ctgaatctcg gcgactcttt ccttggccat
     6181 ttgacgctcc gttgttgaag tgcttgcgcc cctgccaagc gacaacgatg ctcaatgctg
     6241 caagccctct ctgccgcatt ggcgcgcagg gtagacctac acgccagggc tgtgtgcaat
     6301 ctgtggcaaa gcccaccttg ggagggctgc gcggttgcat atcttgaggc gggctatacc
     6361 acctttccgt cgagctggta ctgccccttg tggtcctcga tctcgagcac ccataggtcg
     6421 ggatcgcgcg caacttgccg ggcgatgtag gcgtcagcct cggcttcggc caccgggctg
     6481 ggaccggtgc cgcggctcca ggccgggccg tcatccatcg agctcgcctg cgtgtagacg
     6541 gtgacgcctg cctcgaagcg gttgatcttc agcagcaccg tgccggcatc gggatcgccg
     6601 cgccgcacca cggtcgccgg aatgaaggcg cggtcgcaga tgcgtacctg cgcgctcacc
     6661 catagtccgg tcgtcaggcc catcaccatc gacgcagtct ttactccaaa gcgtcgtcca
     6721 gtccatcgaa gacggcgcgc gcgccgcgcc agcggaagcg cacgaaggcg aagggcaggg
     6781 cctgcaaggc gtcggaatcg ggatcggcca gcgccgccgg cgcgacaagg atcggtcgca
     6841 cgtcaggccc gccgcgcgcc gaggcgagcg acagcgagcc taccgccatg gcgagctcct
     6901 cgggcccgcc gtcggcgacc agcgcgaaca agggctgcgg ccgctcgccg cgcagcgaga
     6961 acagatcctc ggcgccgccg aacagcccgc gcttggcaag ctcctcgcgc aatgccacgt
     7021 cgaccagccg gcggtcgcag gccgccatcg ccgagtcgct gatcgcaggc tcgacgcaga
     7081 gcccggtgcg cgcggtcggc ggctcgcccg ccttgaagcg gcgcaccgcg tcgacgaact
     7141 gtccaagcag gcgggtgagc cgtggactgt cgagcggagc gatcaccagc gcctcggtct
     7201 cctcgccgtc gggccaggcg agcttgcgcc acacgccatc gcgcaagaag tcgcggaagc
     7261 ccgacttgcg ctggcccggc cgcgagccgc ccatgcggcc ggagtggcag agatagagcg
     7321 tgccgcgctc gtcggcggcg atgatgccgg cgactttccg gtcggcgccg gcgcgcggca
     7381 ggttgatctc gcaggtgatg ctctcgcgct tggctggcgc gtcgggcgcg tggcccagca
     7441 gcagggcatc gcgcgccggc ctcggctcga cggcccacca ataggcatcg tcgcgcgccc
     7501 agtagatggt ggtgcgcaat tcgccgccgc gccatgtgac ccgcacgctg cgtgagggaa
     7561 tacccttcag cgcgccctgc aggcgcttga tggcgcgttc gatccgcctc ggctccccca
     7621 cggcccttag catcagcaat tctacccctg tgagttatcc ttgccgatgt ggacaggttc
     7681 ggccatttag cgccctcgag atcaaatcaa gaatggccga accccctctc ctggccctcg
     7741 ccggcatccg ctaccacctg ggcgaccaga ccatcctcga cggcgtcgag ctcggaatcg
     7801 cgcctggcga gcggctgagc ctggtcggcc gcaatggggc gggtaagtcg accttgctga
     7861 agatcctggc gggcgagccg atcgccgatt cgggcacgcg cttcgcccag cccggcgcca
     7921 ccgtggcgac cctgccgcag gagccggatt tcaccggcca tccgacggtc ggccattacg
     7981 tcgctgcagc gctcgccgat gcgctgggcc cgtcggacta ccgcgtcgcg gccctcctga
     8041 ccgaggtgaa gctcgacggc gccaagaatc ccgccgagct gtcgggcggc gaggcgcgcc
     8101 gcgccgcgat cgcccgcgcc ctggtggccg agcccgacgt gctgctgctc gacgagccca
     8161 ccaaccatct cgacctgccg accatcgaat ggctggagga caagctttct gcgtggaacg
     8221 gcgcctacgt gctggtgagc cacgaccggc gcttcctcgc caacctcagc cgcgccgtgc
     8281 tgtggctcga ccgcggcatc gtgcgaaggc tcgacagggg ctatggcgag ttcgaggact
     8341 ggtcgagcgc catcctcgac cgcgaggcga ccgagcggca caagctcgac cgcctgatcg
     8401 agcgtgagac cgaatgggcg ggcaagagca tccgcgcgcg gcgcacgcgc aacgagggcc
     8461 gcctgcgtgc actgggtgag ctgcgtaagc agcgccgcca gcagatcggc ccgaccggcc
     8521 gcgccaccat cgaggtcggt accgctgagc agtcgggcgc gctcgctatc accgcccgca
     8581 acatctccaa gcgcttcggc gaacgggcca tagtcgagaa tttctcgacc cgcatcttcc
     8641 gccgcgaccg catcggcctg atcggcccca acggcgccgg caagacaacg ttgctgcgca
     8701 tgctcatcgg cgagctcgag cccgacaccg gctcggtgaa gctcggtgcc aacctcgtgc
     8761 ccgtcgtgat cgaccagcgc cgcgccgcgc tcgatcccga caggacgccg tgggagatct
     8821 tggccgaccg caacgaccac ttgctggtgc gcggtcggca gatgcacgtc atgacctacc
     8881 tgcgcgagta cctgtttcgc gacgagcagg cgcgccagcc cgtgcgcacc ctctcgggcg
     8941 gcgagcgcaa tcgcctgctg ctcgccaagg cgctggccgc gccgtccaac ctgctggtgc
     9001 tcgacgagcc gaccaacgac ctcgacgccg acacgctcga tctgttgcag gaggcgctgt
     9061 cggactatga cggcacggtg ctgctggtca gccacgaccg cgacttcctc gaccgcctgg
     9121 tgacctcgac cattgcgatg gaaggtgacg gcacggcgat cgagtatgcc ggcggctaca
     9181 gcgactatgt ggtgcagcgc gggccgcgtg agctcgacgc cgcggcaccc gctacgcgca
     9241 gggagaaggc gccgccgcgc gagagcgccc ccaaggcgcg gctgggctac aagcgcgagc
     9301 gcgccctcgc ggagctgccg aaaaggatcg aagccctgca caccgagatc gcggcgctca
     9361 acgcggcgtt gaccgatccc gacctctacc gccgcgacgc ggccgggttt gccgccaaga
     9421 ccgcacgcct cgctgccgca caggccgagc tagacgccgc cgaaaccgaa tggctcgagc
     9481 tcgagctttt acgcgaagaa ctcagcggct gaggctacgc cgcctcgcgg tagaagaaat
     9541 cgtcgtcgag gaagatctcg tcgcgggtgg catcgtcgtt cgatgcgatg gcggtcgcgc
     9601 tggtcgtgcg ctgcgcgagg gtcagcgcct tggccaggca gtcgcgattg aacaaggcca
     9661 tcgacttcga ctcttcgtag atgtcgagca gggcgcgcgc caccgacgca tcgaggccgg
     9721 accgctcgag ctcacgaact tggacacgct ggctcaccag cgactgctgg caagccgcga
     9781 cgcgcgcgca agcgtcgcga aggttgtatt ccagggcaaa gcgatccatg acggtgctcc
     9841 gatttgctac atactcggga ccttgtggct gctaacgcat cttttacgtg agcgttgcac
     9901 cctaaggcct tgatgccagt gtgagacgaa gcattggcgc ttttttcgac cgctttgcgg
     9961 caacctacga acggccgtgt gctgcgctcg cggctgaaat ggggccaaaa gacggcagag
    10021 ggcgctcagg tcagaaccgg ctctcgctcc tcggcgagtc gggatcggac cgcagcaaca
    10081 ggatccagca ccgcgtctcc gccgcccggt ggaagtggtc ctccaggtag ccgcgataga
    10141 gacgcatcat gtcgtccgcc cattgcgggc tggtcgcgaa cttcggcacg aggacgtaac
    10201 gcacgccccc caaaaactcg ctggctggcc gcttcggtgc actccaggtc gaccacaggt
    10261 tgacgccgcg cgcgggctct acacccagca tgaagggcag gggattgacg ctgtcgagca
    10321 gggcgatgcc gccgggtgga aggcctctca gcaggtcggc ggcctccatg agcaccacga
    10381 cgtactcgta atcggagagc tggtagagcg gctgggccgg cgcatccccg gcgcgcgacg
    10441 ggtagtcgaa gttgttcgag aagctcagga aggtgccgcg cgggcccgcc ggcacggcaa
    10501 ggccgccgag gttggtgtgc tcgacgacgt acacgccggg ccggtcgcgg gcgtaggcct
    10561 ggtagcccgc gatgctggcg gcgtagccgc cgacggcgaa caggggaaac agcagcagcg
    10621 tcagcagcca cggcgcgacg tcgcggttgt cgagcgaagc gaaggcggtg cgcagccggt
    10681 cgtagaggat gaacagcacg acgatggccg acggcatgcc cgcggcctgg gagttctgcg
    10741 acagcagcag cagcgacatg accagcagga agacgagcgt caggggcaag cggaacgtcg
    10801 cgcggcccga ccaccacatc cccgcgccca ccgcgacggc ggcgagatag ggcccgtact
    10861 ggccgatcgc ggcgacgaag ttgttgaagt gcagaatcgc cgccttgcgc acggcgccgc
    10921 t
//
