LOCUS       NC_021039.1            21356 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_021039.1 Ruminococcus champanellensis 18P13 = JCM 17042, complete
            sequence.
ACCESSION   NC_021039
VERSION     NC_021039.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:21:20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2130994
            Orig. end    :: 2152350
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21356
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[2140994:2142350]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11356
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..21356
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21356
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="4"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(914..1084)
                     /locus_tag="ctg1_1967"
                     /transl_table=11
                     /translation="LAELNERYKDKPTSKAVYEVDGQRYAVTSHFVGEKDLDKVLYELA
                     FKRAFQKTEKN"
     CDS             complement(1250..1648)
                     /locus_tag="ctg1_1968"
                     /transl_table=11
                     /translation="MSKKAKTEVDEKSAVIITDAVLAENQAKLDSYEKSIKAVQERRRK
                     VIIDSKLYTYDKLSQLYGGAEGQALLDAVTAEHTLIGKLTASGMTYEQIGELADDSSAD
                     ADNSSDESYSEKYAKQMSFSETDHSYSE"
     CDS             2596..3267
                     /locus_tag="ctg1_1969"
                     /transl_table=11
                     /translation="MKTEKKKRGRPPKHKAMEFEGMTYEGAINHALDKEVRADLDKCLA
                     DKDESQLTDDERKYLKRKKEKKSYTLNVRFTESEMQDILSKCEQYGYKNKTEYIRDCVR
                     ARVDLTPDRSEIAECNRLMKRIGANINQILVRLYSTGHIYAEDITEIKKGVNEIWHTLL
                     SIRSGQQSAQRSLTSQEMIRPSTVYMSTLMLAEPIAQEQARTSEPSETQEQDAPKSLPT
                     T"
     CDS             3264..4754
                     /locus_tag="ctg1_1970"
                     /transl_table=11
                     /translation="MIQSFAPGEVTPEQAMQIGEELCDRYLKGDYQYVIAVHHDKSHLH
                     CHIIFNNTNLYNGLSFTTEHNQGRKSERAWAELREISDEICAEHGISVISEPEKGHGVS
                     HFERNMQKEGKSWKDKLRVRIAEVMLYSRDFKDFLEKCSECSIEYVYKPSNKVKLKFRL
                     SGDGQQKFTRADTLGADFTPERIAEQIAEIQEKLSAANVTPDMLIEAPKPVVPKTEPKP
                     TQTVTAPTKPKQSAEPETITETSETAKRKAAAEQVEKFFAARRARRQAQLDMLNATAIN
                     PKPEPSARTPQPTPTESKAPEKKEDPWKAIRGMGRANEIIADLEAGGVMSFSELSGFFF
                     NTPHSDDHTTERADLKKKFTAIDTLIAKMKHRDELEPVYKEYQGKSGWSQSRFKKKNAA
                     TIEDYEQTVKYIKEHIKKYAVDGKPPTMLDLLEKSNKLKSKWNRLNVEHTAFLTKRETA
                     KKYTRQVRQYINEQQMKREREKSRQRTQAKHRNKNTLE"
     PFAM_domain     3267..3836
                     /aSDomain="Relaxase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03432.16"
                     /description="Relaxase/Mobilisation nuclease domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1970_0117"
                     /evalue="9.10E-36"
                     /label="ctg1_1970"
                     /locus_tag="ctg1_1970"
                     /protein_end="191"
                     /protein_start="1"
                     /score="123.8"
                     /tool="antismash"
                     /translation="IQSFAPGEVTPEQAMQIGEELCDRYLKGDYQYVIAVHHDKSHLHC
                     HIIFNNTNLYNGLSFTTEHNQGRKSERAWAELREISDEICAEHGISVISEPEKGHGVSH
                     FERNMQKEGKSWKDKLRVRIAEVMLYSRDFKDFLEKCSECSIEYVYKPSNKVKLKFRLS
                     GDGQQKFTRADTLGADFTPERIAEQIA"
     CDS             4773..5366
                     /locus_tag="ctg1_1971"
                     /transl_table=11
                     /translation="MSKIGYIRVSTEHQETARQQEIMCSYQVDRIFSEKLSGANTDRPQ
                     LRAMLDYVREGDTLYIESISRLGRSTKDLLNIIDTLTDKGVTLISHKEKIDTDTPAGKF
                     MLTVFAALSQLEREQLKQRQREGIEIAKAQGKYTGRKPIPTDWTRFGQLYGEWRAKHIT
                     GRDFMRRMNMSANTFYRRVREYELRHGITEPTSA"
     PFAM_domain     4782..5183
                     /aSDomain="Resolvase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00239.23"
                     /description="Resolvase, N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1971_0118"
                     /evalue="3.40E-42"
                     /label="ctg1_1971"
                     /locus_tag="ctg1_1971"
                     /protein_end="137"
                     /protein_start="3"
                     /score="144.1"
                     /tool="antismash"
                     /translation="IGYIRVSTEHQETARQQEIMCSYQVDRIFSEKLSGANTDRPQLRA
                     MLDYVREGDTLYIESISRLGRSTKDLLNIIDTLTDKGVTLISHKEKIDTDTPAGKFMLT
                     VFAALSQLEREQLKQRQREGIEIAKAQGKY"
     CDS             5897..6463
                     /locus_tag="ctg1_1972"
                     /transl_table=11
                     /translation="LVVLNQNHCKYRPKAMSLXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     STSTSRPDTAYKLFIIKNNYFIIWQ"
     CDS             complement(7594..9966)
                     /locus_tag="ctg1_1973"
                     /transl_table=11
                     /translation="MVKNKILKRIVAGLSCIALSTTMLTSLPAFADDYVDEYQYYSTLD
                     PNGEEYQEWKSNLASSAVSVPQNRMLKSILKNNTLIANDYIEFNTASNGHYTIGTIGGN
                     PNSSTDDNKKMLFGHPGGGTSKTTIVVGESINEFTSSNVTYDADGSKSVSKASYDGVDV
                     TQELSIIENSATGRDDVVKIKYIVKNDTEYAKQVGIRIMMDTMLGGNDAAPFRVNGSDV
                     TTETVYSGSNIPQIWQAFDSATNPGVVAQGTFYKSGDRKPDKVQFTNWGNVTSTLWDYV
                     TQPGRSNGDSAVSITWNKDTFTSGETREFVTYYGLSELEQNLIPPLALSVYADNKVSIS
                     NFNYDDINANVYXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNITIAA"
     CDS             complement(10001..10156)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1974"
                     /sec_met_domain="TIGR04223 (E-value: 2.2e-12, bitscore:
                     43.9, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLMSIAKKASTALAALALVVATTSVPSACFHWFAQPVEPEELR
                     NYVNRK"
     aSDomain        complement(10019..10132)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1974_0033"
                     /evalue="4.10E-12"
                     /identifier="TIGR04223"
                     /label="ctg1_1974"
                     /locus_tag="ctg1_1974"
                     /protein_end="46"
                     /protein_start="8"
                     /score="43.9"
                     /tool="antismash"
                     /translation="KKASTALAALALVVATTSVPSACFHWFAQPVEPEELRN"
     CDS             complement(10310..11356)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1975"
                     /sec_met_domain="AgrB (E-value: 2.9e-20, bitscore: 69.5,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKLAKSIAHFFVVQNITEESKEVIYAYGMELLISDVLNTIIVL
                     LIALFSHTLPAVVVFIAVFMGLRQFVGGFHANSHXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXEEKSVKLRKRSCILAVTLSVVTIALLVFQYQKLSLYVSSGMLLSAIMALLGHFL
                     NRGDNSKR"
     PFAM_domain     complement(11120..11338)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1975_0119"
                     /evalue="2.40E-19"
                     /label="ctg1_1975"
                     /locus_tag="ctg1_1975"
                     /protein_end="79"
                     /protein_start="6"
                     /score="69.5"
                     /tool="antismash"
                     /translation="KSIAHFFVVQNITEESKEVIYAYGMELLISDVLNTIIVLLIALFS
                     HTLPAVVVFIAVFMGLRQFVGGFHANSH"
     CDS             complement(11476..12774)
                     /locus_tag="ctg1_1976"
                     /transl_table=11
                     /translation="MIELPVLIENIIEIVNVAIEMMLVFLYFSLLSKAKVNKAVLYLSY
                     LLSTVILSATVLLTDNILVYLITTIILISSMSFICYDDSIRHKIFWNILFLLIISISEP
                     IVIGLLCIANMGTPDEFLESGLGRYLGMVGTNIIYLWLIGLMHRIINKKIRELPIKYWI
                     LIIVIPIISIFLLQTMLDGFVGSNTYSYVSLGVSLAGIIFINLAMFNFFESFEDKIKLK
                     YLETIKQQEQENYKLLTLSYKQVREFKHDIENQFLVLNDMLENNDTDSAKEYLVKLSSF
                     VRLANRLCYTGNNAVDSIVNIKGSLAQTYGIEFICKVNIITNIKADELELCRIIGNALD
                     NAIEGCQRAGVSHKHIWISLMEEREKLFIVITNTSDKVDTSVLTSTKKEQGLHGIGINS
                     IKSSVDRLGGLVSFDYDDGIFKLNIMVRNCLQI"
     PFAM_domain     complement(11497..11796)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1976_0120"
                     /evalue="7.40E-23"
                     /label="ctg1_1976"
                     /locus_tag="ctg1_1976"
                     /protein_end="426"
                     /protein_start="326"
                     /score="80.5"
                     /tool="antismash"
                     /translation="DELELCRIIGNALDNAIEGCQRAGVSHKHIWISLMEEREKLFIVI
                     TNTSDKVDTSVLTSTKKEQGLHGIGINSIKSSVDRLGGLVSFDYDDGIFKLNIMV"
     CDS             complement(12771..13466)
                     /locus_tag="ctg1_1977"
                     /transl_table=11
                     /translation="MNIAIVDDEPVFLKQLHNRLREMKLPDCEIHEFTSGRDLLSFYVK
                     GMYEVIILDVEMPDLTGLQTAERIRQIDGSVIISFLTNYAEFAVKGYDVGAFRYILKNQ
                     PDYVYTKQLNSIIAECQQRFRTFTFNNKNLSFKFRLTDILYFEGHRRKVSLFTVNGELE
                     YGGDFSTVCGELLKYNFAIINRGILVNLDHIQNITKYDIILSNGRKIPIGKTYKDEIVA
                     RYLNYATGR"
     PFAM_domain     complement(12804..13058)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1977_0122"
                     /evalue="1.70E-13"
                     /label="ctg1_1977"
                     /locus_tag="ctg1_1977"
                     /protein_end="221"
                     /protein_start="136"
                     /score="50.7"
                     /tool="antismash"
                     /translation="KFRLTDILYFEGHRRKVSLFTVNGELEYGGDFSTVCGELLKYNFA
                     IINRGILVNLDHIQNITKYDIILSNGRKIPIGKTYKDEIV"
     PFAM_domain     complement(13155..13460)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1977_0121"
                     /evalue="3.30E-18"
                     /label="ctg1_1977"
                     /locus_tag="ctg1_1977"
                     /protein_end="104"
                     /protein_start="2"
                     /score="66.0"
                     /tool="antismash"
                     /translation="IAIVDDEPVFLKQLHNRLREMKLPDCEIHEFTSGRDLLSFYVKGM
                     YEVIILDVEMPDLTGLQTAERIRQIDGSVIISFLTNYAEFAVKGYDVGAFRYILKNQ"
     CDS             13742..17035
                     /locus_tag="ctg1_1978"
                     /transl_table=11
                     /translation="MAFVTSAGTLDKRDESVRQMLADKSDFIGAIRLPGGKNGAFKDNA
                     GTEVTTDIIFLKKHEGKSLAEMSDIPDWVHIGETADGLPINKYFEQHSDMVLGTVVEGN
                     KLYGSGTMVVAEDGFDLRSALHEAVGKLSAEISHERGRDVYAKTADGVQVQIPSKLRNY
                     SFFLSDNQVFFKKNNAACEFRFDKGTAQHKRFKAFIELRDLTRELIEAMELDKPDSVIK
                     DLQAKLNVAYDDFYKKFGLIHSQTNKRYFAEDVSYNLVAGLEKSYDKTKLLEKSDIFTK
                     RTIVPTNAVEHVDTALEALTLSIAEKARVDFEYMSGLTGMTEDELKHDLTSEIFKIPHT
                     ENEYQTASEYLSGDIRKKLREAEEIAEYDPDFNINVSALKQAMPEPLKAGDIDIKLGAA
                     WLDPKYYEQFMYELLQTPAYQRSDSPSSRWNKSAIVGVEYSVHANSFHVSNKSSDRSVL
                     ATQKYGTHKMNAYDIFEHLLNLQEPKVYKTIEVPDGLGDTKEKRVVDIDATRVVQRKAD
                     DIRKAFKAWIFKDPQRREAIVEKYNELFNSIRPREFDGSALSFPMMTSDIKLHDHQKNA
                     IAHAMFGGNTLFAHCVGAGKTFEMIATAMESKRLGLCTKSLFAVPNHLTEQIGDDFQKL
                     YPGANILVATKKDFQKANRQQLFAKIATGNYDAVIIGHSQLGKIPVSKERQVMTIQSQI
                     DDILRGIEELKKSEGSKFQIKAMERTRKSLQKQLDKLEKANQDDTLTFEQLGIDRLFVD
                     EAHEFKNLFVATKLQNVAGISNSASQKALDLFLKCRYLDEKTGGKGVVFATGTPLSNSI
                     TELHTMMRYLEYDFLNNHGLQHFDNWVAVFGDQKTDWELKPAGNGFKERTRIANYTGLP
                     ELMSMFKQVADIRTADTLKLDVPDCEYQVVQVEATPFQQELVQELADRADAINAGNVDP
                     TIDNMLKITSDGRKLGLDPRLIDPSFEDNPDTKLNRCVENVARIHAETAEDRLTQIIFC
                     DLGVPHKATGEAEAEDEDADDAKDKKFIAEVESLEEECDFCVYDDIRDKLIARGIPAEE
                     IAYIHDAKTEQQKSDLFDKVRNGEIRVLLGSTAKMGTGTNVQKRLKLAP"
     PFAM_domain     15440..16051
                     /aSDomain="ResIII"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04851.17"
                     /description="Type III restriction enzyme, res subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1978_0123"
                     /evalue="1.80E-05"
                     /label="ctg1_1978"
                     /locus_tag="ctg1_1978"
                     /protein_end="770"
                     /protein_start="566"
                     /score="24.9"
                     /tool="antismash"
                     /translation="IKLHDHQKNAIAHAMFGGNTLFAHCVGAGKTFEMIATAMESKRLG
                     LCTKSLFAVPNHLTEQIGDDFQKLYPGANILVATKKDFQKANRQQLFAKIATGNYDAVI
                     IGHSQLGKIPVSKERQVMTIQSQIDDILRGIEELKKSEGSKFQIKAMERTRKSLQKQLD
                     KLEKANQDDTLTFEQLGIDRLFVDEAHEFKNLFVATKLQNV"
     PFAM_domain     16151..16582
                     /aSDomain="SNF2-rel_dom"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00176.25"
                     /description="SNF2-related domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1978_0124"
                     /evalue="4.80E-07"
                     /label="ctg1_1978"
                     /locus_tag="ctg1_1978"
                     /protein_end="947"
                     /protein_start="803"
                     /score="29.1"
                     /tool="antismash"
                     /translation="TGTPLSNSITELHTMMRYLEYDFLNNHGLQHFDNWVAVFGDQKTD
                     WELKPAGNGFKERTRIANYTGLPELMSMFKQVADIRTADTLKLDVPDCEYQVVQVEATP
                     FQQELVQELADRADAINAGNVDPTIDNMLKITSDGRKLGL"
     CDS             17659..18186
                     /locus_tag="ctg1_1979"
                     /transl_table=11
                     /translation="MDHERIIYIYDYLSRYTDENHDVSISQIQEHLANVCNLTRVKNVT
                     IRRDLDRLTAMGNHIVKHNREHNTAYYALIDKGFSFNEIRFIVDSISINKFLTAFQKKT
                     LIKKFEGMCSDAEIRQLISRIVLNERCSSTLDLLENLDKIHRLIGERQKIDFEYGKYDE
                     TTKQIAYYYKKR"
     CDS             18283..18639
                     /locus_tag="ctg1_1980"
                     /transl_table=11
                     /translation="MKNILGGEVSYVRLPPEDNYEGFVTDMFAPEYFTVVTLRVKKYLL
                     DEMRENFEDYASILHDEDADYVRIRVRVGINRKFYLWLMQYGDGVELVSPAKERAEYLE
                     EVRKMLRAYPEFAE"
     PFAM_domain     18325..18612
                     /aSDomain="WYL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13280.8"
                     /description="WYL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1980_0125"
                     /evalue="6.00E-11"
                     /label="ctg1_1980"
                     /locus_tag="ctg1_1980"
                     /protein_end="110"
                     /protein_start="14"
                     /score="42.8"
                     /tool="antismash"
                     /translation="PPEDNYEGFVTDMFAPEYFTVVTLRVKKYLLDEMRENFEDYASIL
                     HDEDADYVRIRVRVGINRKFYLWLMQYGDGVELVSPAKERAEYLEEVRKML"
     CDS             18881..19411
                     /locus_tag="ctg1_1981"
                     /transl_table=11
                     /translation="MAVYIVFDVETPNRSNDRMSAIGISAIKDNKIVANYFSLVDPETH
                     FDYFNTKLTGIDADKVKGAPNFAELWKKIDPIMSKGILVAHNAVFNMSVLRACLRDYGI
                     SWKPTAKYLCMVRIGRRVLPDMKHNLNVMCDHYGIALDHHQADSDSHACAEILLRYIES
                     GIDVREYVKEYKL"
     PFAM_domain     18893..19351
                     /aSDomain="RNase_T"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00929.26"
                     /description="Exonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1981_0126"
                     /evalue="7.10E-16"
                     /label="ctg1_1981"
                     /locus_tag="ctg1_1981"
                     /protein_end="157"
                     /protein_start="4"
                     /score="59.3"
                     /tool="antismash"
                     /translation="IVFDVETPNRSNDRMSAIGISAIKDNKIVANYFSLVDPETHFDYF
                     NTKLTGIDADKVKGAPNFAELWKKIDPIMSKGILVAHNAVFNMSVLRACLRDYGISWKP
                     TAKYLCMVRIGRRVLPDMKHNLNVMCDHYGIALDHHQADSDSHACAEIL"
     CDS             20225..20719
                     /locus_tag="ctg1_1982"
                     /transl_table=11
                     /translation="MINDLHTPQILLFSEQEEPQSYEIYVYGTDDLVEQHKDSFCLALC
                     RYLDEIHISQKTLARLTGIAPSTLSRYLSGKRKMQYDCLCAVCIALRLHPCRQRYLFSL
                     LMYALPCYQDFRKADKNIIMAYLDGCAFNNRYTLTACNEQLKAIHAKPLTHLTSAKGDS
                     V"
     PFAM_domain     20366..20455
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1982_0127"
                     /evalue="3.10E-06"
                     /label="ctg1_1982"
                     /locus_tag="ctg1_1982"
                     /protein_end="77"
                     /protein_start="47"
                     /score="27.2"
                     /tool="antismash"
                     /translation="LDEIHISQKTLARLTGIAPSTLSRYLSGKR"
     CDS             20719..21150
                     /locus_tag="ctg1_1983"
                     /transl_table=11
                     /translation="MGRFMYVHFGDDVPRNIEKEYNKLLRKERYLEERDAENGMIYADF
                     DAVLAANPDPASIPISEEEEQEQIRQRNRHDYLPDALELLKSDFPEGYELIRDYFLRED
                     KVTMWYLVEKYGLSIDVVRYRIKIAKQKLKEYIILHENE"
ORIGIN
        1 gtatctgctt gtgatttttg taggataccg ttgtcactct ctgctgtgcg agatttccga
       61 tataaatctc attgttaaga atgccacgca ccatacaatc attccacaga tgtgaagtca
      121 caaggggatt atctttgcct ttaagctgat aacgatgatc cgagggagtt gcgatgccgt
      181 ccttgttaag ctgtatagcg atctgcttcg gacttaaccc tcttgccctc tgctcaaata
      241 tacgtcttac gataacggcg gcatcttcat caatcaaggg cgtatgcttt tcatcatctg
      301 ccttgatgta accataagaa gctgaagccg ccagatactt gccctgccga gaatttgctg
      361 ccatgacact gcgtaccttc tttgacgtgt tggcggcgtg ccattcgttg aataaattca
      421 tcacaggcat aagatccatt gccgaactgt ttctgtcaag cgtgtctaca ttgtcgctca
      481 gggcgatgaa gcggatattg aatgaaggaa aaatgtaatc tatatactga ccgacctcga
      541 tataatttct tccgaaacgt gaaaggtctt tacagaggat aagatttatc tttcccgact
      601 ttgcatcatc aagaatctgc ttgatacctg gtctatcgaa acttgttccc gaatagccat
      661 cgtcctcgca tatctcgata agattccacc cctcctgctt gctgacatat tccgtcagca
      721 tcttcttctg attttcaatc gaaagggatt cgcccgcacg ttcgtcctcc tgcgacaaac
      781 gcacatagat cccgacattg taagtagttt gctttgccat aataactcct ttccaatcaa
      841 agcaaaccat attcgatgat acaactatta tagcgcagaa aaccgaatat ggcaagtctt
      901 ttttcaaaac tttttagttc ttttcggttt tctgaaacgc tcttttgaaa gcaagttcat
      961 aaagcacctt atcaaggtct ttttcaccca cgaaatgact tgtcacagca taacgctgac
     1021 cgtccacttc gtacacggct ttgctggtcg gcttatcttt atatctctca ttcagctcag
     1081 ccaaagtaaa tcctgtatct tttcttggca agtgtctcct ttccgcctgc gattatctat
     1141 ctctacacgc aatggctttt tgttgcaggg gcgttacgcc tgcacaggtg ctgtacggaa
     1201 cggcagagcc gtcccttaca cagcaatcgt tttgttgtcg gaatatatgt tactccgaat
     1261 aggaatgatc tgtttctgaa aagctcatct gcttagcgta cttttcggaa tagctttcgt
     1321 ccgagctgtt gtcagcatcg gcagaactat cgtcagccag ctcaccaatc tgctcatagg
     1381 tcataccgct tgctgtcagc ttgccgatca gcgtatgctc cgcagtcaca gcatcgagaa
     1441 gtgcctgtcc ctccgcaccg ccgtaaagct gtgagagctt atcgtaggtg tagagcttgc
     1501 tatcaatgat gaccttgcgc ctgcgctcct gcacagcttt gatagacttt tcgtagctgt
     1561 cgagctttgc ctgattctcc gcaagaacag catccgtaat gataacagcg gacttctcat
     1621 caacctcggt cttagctttc ttactcattc tcatcacctc ccaatgtatt ggatttaggg
     1681 ataataccct atgctaatat tatagcattc tcggacagca aaagtctatt cgcattgcgc
     1741 aagaagttga gtgcgccata aaacttcttc attcgtgaaa ttgttatggg gaattttgca
     1801 gaaagcagac cgagcattgc aaatccgagc catatcacat tgactgcata ctgcataggt
     1861 caccatttct gatttattca atacggagaa ttattatcac ggagcaacta tttttataaa
     1921 aatcatgccc gtttcctgat tgaacgtgct tgtatatata gagggggttt tatccgagtg
     1981 ccgccgtgac ctattcacat tctgtataga aatatgctgt tgaatttagg cacaagggag
     2041 aaccgtcatg aacaaagtgt aaacttttct gaaaaacaac gccattttct caaaaacacc
     2101 ggtagaaaag tgaagggctt tgacgttgtg acgatcacac gcacccctgc atatcatttt
     2161 catcataaaa tttttctgcg gtatacttaa cgaagcggtc aataatttgg tattaactta
     2221 tgggagcata tttcatagga ctgccgccca gactgcgcaa taactgcgct gagccagttt
     2281 acaatttcaa gagtgatgat attgagtgca tcacgcagga gcgtgagcga gtatgaccgc
     2341 cgacctaagc ggcggagagt ttaagtcgca tagctccaaa ttcgctgacg gagcatcgaa
     2401 agcctgagtg atatgaaaat cccacaggct ggaaaatagc gctacagcgc aacaaaaata
     2461 acaagcattg tattttgcgc cgcacagcga gcgaaaatac caaatgcttg ttagggacac
     2521 cccaagcccc gaaacgaccg cacagcggtc aagaaaatcg gctaacgccg aaatacaaac
     2581 aaaggagaca ccactatgaa aaccgagaaa aagaagcgtg gaagaccgcc caaacacaag
     2641 gctatggagt ttgagggtat gacctacgag ggagcaatca atcacgcact tgacaaagag
     2701 gtcagagccg accttgacaa gtgccttgcc gacaaggacg agagccagct taccgacgat
     2761 gaacgcaagt acctgaaacg caagaaggag aagaagtcct acaccctcaa tgttcgtttc
     2821 accgaatcgg aaatgcagga cattctttcc aagtgtgagc agtacggtta caagaacaag
     2881 accgagtata tccgtgattg tgttcgggcg agggttgatc tcacgcccga ccgttccgaa
     2941 attgccgagt gtaaccgtct gatgaaacgc atcggagcaa acatcaacca gatacttgtc
     3001 cgactttaca gcacaggtca catctatgcc gaggatatta ccgagataaa gaaaggggta
     3061 aacgaaattt ggcatacact tctatccata cgatcagggc aacagtcagc gcagcgatcg
     3121 cttacatcac aagagatgat aagaccatcg acggtttata tgtcaactct tatgcttgcc
     3181 gagccgatag cgcaggagca agcgaggact tccgagccgt ccgaaacaca ggaacaggac
     3241 gcacccaaat ccttgcctac cacatgatac agagctttgc ccccggtgaa gtcacgcccg
     3301 aacaagctat gcagatcgga gaggagctgt gcgaccgtta tctgaaaggc gattatcagt
     3361 atgtcattgc tgttcatcat gacaagtcgc acctgcattg ccacatcatt ttcaacaaca
     3421 caaatctgta taacggtctg agctttacca ccgagcataa tcaaggcaga aagtctgaaa
     3481 gagcgtgggc agagttgcgt gagatttcgg acgagatatg tgctgaacac ggtatatctg
     3541 ttatctccga gcctgaaaag ggacatgggg tatctcactt tgagaggaat atgcagaaag
     3601 agggcaagtc gtggaaagat aagctccgtg tcaggattgc ggaggtcatg ctttacagcc
     3661 gtgacttcaa ggattttctt gaaaaatgtt cggagtgcag tatcgaatat gtttacaagc
     3721 caagcaataa ggtcaagctg aaattccgtt tatcaggtga cggtcaacag aagtttacaa
     3781 gagccgacac cctgggcgca gacttcaccc ccgaacgcat agccgagcag atagcggaga
     3841 tacaggaaaa gctgtcagcg gcgaatgtca ctcccgatat gcttatcgaa gcgccgaagc
     3901 ctgttgttcc aaagaccgag ccgaagccga cacagacagt caccgcaccg acaaagccga
     3961 aacaatctgc cgagcctgaa actatcaccg aaacaagtga aaccgcaaag agaaaagctg
     4021 ctgcggaaca ggtggagaag ttctttgcag cccgacgagc aagacggcag gcacagcttg
     4081 atatgcttaa cgcaactgct atcaatccga agcctgaacc gtctgcccgg acaccacagc
     4141 ccacacctac ggagagtaaa gcacctgaaa agaaagaaga tccgtggaaa gctatcagag
     4201 gtatgggcag agcaaacgaa atcatcgcag accttgaagc tggtggcgtt atgtcattca
     4261 gcgagctgtc tggattcttc ttcaatacac ctcactccga tgaccacaca actgagcgtg
     4321 ccgatctgaa aaagaagttt acagctatcg acacgctcat tgcaaagatg aagcaccgtg
     4381 acgagctgga gcctgtttac aaggagtatc agggcaaatc gggctggtcg cagagccgtt
     4441 tcaagaagaa aaatgccgcc actatcgagg actacgagca gacggtcaag tacatcaagg
     4501 agcatatcaa gaagtatgct gttgacggca aaccgccgac gatgcttgac cttttggaga
     4561 agtccaacaa gctgaaatcg aagtggaaca ggcttaatgt cgagcatacc gcattcctca
     4621 ccaagcgtga aacggcgaag aagtacaccc gacaggtgcg ccagtacatc aacgaacagc
     4681 agatgaagcg tgagcgtgag aaaagccgtc agaggacaca ggctaaacat agaaataaaa
     4741 atacacttga ataaagaaag gaaacaacaa ctatgagcaa aataggttat atccgtgttt
     4801 ctacggagca tcaggaaaca gcgagacagc aggagatcat gtgcagttat caggttgacc
     4861 gcatcttctc cgagaagctg tcaggagcga acaccgaccg ccctcagctc agggcaatgc
     4921 ttgactatgt gcgtgagggt gacaccctct acatcgagag tatcagccgt ctgggacgct
     4981 ccacaaagga cttgctgaac atcatcgaca ccctcacaga caagggagta acgctcatca
     5041 gccacaagga gaaaattgac accgacactc ctgcgggcaa atttatgctc accgtgttcg
     5101 ctgcactctc acagttggag cgtgagcagc tcaaacagcg acagcgtgag ggcatcgaga
     5161 tcgctaaggc tcagggcaag tacaccgggc gaaagcctat ccccaccgac tggacgaggt
     5221 tcggtcagct ctatggggaa tggagagcca agcacatcac gggcagggac tttatgcgga
     5281 gaatgaatat gtcagcaaat actttctacc gccgtgtgcg tgagtatgaa ctccgtcacg
     5341 gcatcaccga gccgacctca gcttgaccgt caggcgaacg gaaatgccac acatcactat
     5401 ccgagcctgc ggagcggaat tctaaccgct gaaaagaaaa agccctcaga aacgcttaca
     5461 agagcatttc cgagggcttg cggttattca gttccaatag agtttgtgcc tgttgtggtg
     5521 tgccccacaa tgcctattca gacttgtgtg gaacgaaaaa tatagtattt ggcaataaaa
     5581 caagataaca ataaatttat agtttagtta actacataga catttccctt tatggcgatt
     5641 tcgtttatta tggcactacg gttcaaatct ttttgggaca ataaaacaat acctataata
     5701 ttaatatcag attgcttaat agtatcttta cctgtattaa taccgtttct tatgttttca
     5761 aattcgtctt ccaaataagc gtgtttatca tttattatat taacaaactt atctaatggt
     5821 gaaatgagct tttcgccagc atagaacaac gggataccat acactcctct ttcgtcattt
     5881 tgaggatttt gaatcgttgg tagtgttgaa tcagaatcat tgtaagtatc gacccaaagc
     5941 catgtcactg nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     6361 nnnnnnnnnn nnnnnnnnnn nnnnttcaac ctctacttca aggccggaca ccgcttataa
     6421 gctgttcatt ataaaaaaca attattttat catttggcaa tagctgttct gttcccattg
     6481 aataatcatt cgatgtatcc caattagacc aatctgctgc atttagtcta aaatggatta
     6541 caaactgttt attaggttga agttcaacat cggtattaaa tttgattttt gcatatgtat
     6601 ttccgtaatc gtcattaaca aattcacaaa ccgaagtatt acctaagtat tgattatcta
     6661 cagcaagcca gtcgcaatgg tattcaaggt tttctttatt gtctgcatta aatacataat
     6721 ttatagttat atcactcatt tttaaaaggc ttgtcagagt tgttagttat aactatattg
     6781 ggatttatag tatttgagtt actaatacct gcattgcaag attctactgt tatttcaggt
     6841 gatttctcat catcttgaat tacccctgga ttgatagttg gcgtaacagt tgtatctatt
     6901 tcaccatcat tatcaagatc aatgttaata aaaaatgaac catctgataa atttaagaat
     6961 aatacagatc cactattcac agagatattg gtatacaaat agatgtttcc atcaatattg
     7021 cacataatat cagtgttttg atcagcaagt gaattgattt tacaatcata attatcatca
     7081 gcaaattgag ccagtaaaat cggattgcca actgatgtta aagggtcaaa tttaaaatta
     7141 ttcccttcat gaacctctga atttgtgtaa taatatgaac aggtttcgtt tgaaaagaat
     7201 aaatcaaaat aacctgaaat agcaagctta tttgaaagtg tcttggtttc ttctatggca
     7261 ttagatgtaa gattgtttat ttgcctattt ttgttctcat gggcagcttc ataaatgatt
     7321 ttgtatcttt tatgtttttt aatatctcat ctatgcattc ctgactctgt attaacccca
     7381 tatgatcttg atcaaagatt tttatatcca aaagatcgtg attaaaattc attgttgcac
     7441 tttcaattgg aactacacta tcgccaatac catattctgg aacgaattgc aatcctctat
     7501 cgccaggaca atgttgaata gttgaaatgg tatttctatt acttcctact aatgctattc
     7561 ttttcagatt attagtattg ttttgggata tttttatgcg gctatggtta tatttnnnnn
     7621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn atatacattt gcatttatat catcataatt
     8941 aaaattggaa atactaacct tattatcagc gtatacactt aatgctaacg gaggaattaa
     9001 attctgttct aactcactca atccataata ggtaacaaat tctcgtgttt caccactggt
     9061 gaaagtatct ttgttccatg tgatggatac tgcactatct ccattagatc gtcctggctg
     9121 agtcacataa tcccatagcg tacttgttac atttccccaa ttagtaaatt gtactttatc
     9181 aggttttctg tctcccgatt tgtagaatgt accttgtgct actacaccgg gattagttgc
     9241 ggaatcaaag gcttgccata tttgcggaat attagaacct gaatatacgg tttcagttgt
     9301 tacatcagat ccgtttactc tgaatggcgc agcatcatta ccaccgagca tagtgtccat
     9361 cataattctt atgcccactt gtttggcgta ttctgtatca tttttgacga tatacttaat
     9421 cttaacaaca tcatctcgtc cagtcgccga attctcaata atagatagtt cttgtgtgac
     9481 atcaacacca tcataagaag ctttggaaac acttttagaa ccatcagcat cataagttac
     9541 atttgatgat gtaaactcat ttatgctttc accaacaaca attgttgttt ttgatgttcc
     9601 tccacccgga tgaccgaaaa gcatcttttt attatcatca gttgaactgt tagggtttcc
     9661 tcctattgta ccaatagtat agtgaccatt acttgcagtg ttgaactcaa tgtagtcatt
     9721 tgctattaaa gtattatttt tgagaatact tttaagcatt ctattttggg gaacacttac
     9781 agcagaactt gccagatttg atttccattc ttggtactct tcaccattag gatctaacgt
     9841 tgagtaatat tgatattcgt caacataatc atcggcaaaa gcaggtaaac tcgtaagcat
     9901 agttgtagat aacgcaatac agctaagacc tgccacgata cgtttcaaaa tcttattctt
     9961 aaccatttca taccaccttt ctgcaacaca cagttgccaa ttatttcctg tttacatagt
    10021 ttctcagctc ttctggctct acaggttgtg cgaaccaatg gaagcaagca ctcggaactg
    10081 atgtggtagc taccaccagc gcaagagccg ccagtgccgt agaagccttc tttgctatgc
    10141 tcatcagctt tttcattaca aatccctcct ttcaaacagt tcagataagt caggctcttt
    10201 cggttgataa aacgtaatac cgcaaacgct gccatttgag atatacagca ccagccttac
    10261 aagagcaaga attacaatcg ccaaaatact ccgtttttct ctttccttat catcgtttac
    10321 tgttatcacc ccgattcaaa aagtgaccga gcagtgccat gattgctgac agcagcattc
    10381 cgcttgatac ataaaggctt agtttttgat attggaatac aagcagtgca atcgtgacaa
    10441 cggatagggt aacagctaag atgcagcttc ttttccttag cttgacactc ttttcctctn
    10501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11101 nnnnnnnnnn nnnnnnnnga tgactgttag cgtgaaaccc acctacaaac tgtctcaacc
    11161 ccataaatac ggctatgaat acaacaaccg caggcagcgt atgggaaaac agagcaatca
    11221 gcaggacgat aatggtattc agcacatcag agatcagcag ctccattcca tatgcgtaga
    11281 tcacctcttt ggattcttcc gttatgttct gaaccacaaa aaagtgtgct atgctttttg
    11341 caagttttga aatcatttct gaatcacttc ctgcaaaaat cataacacaa gttgcaaatt
    11401 ttttcaatag gttttgagaa aaaaggtctc aaaagtgtcc ccaaatgtcg tcttcttgtc
    11461 ccgaaatgca aatagttaaa tttgtaaaca attacgaacc ataatgttca gcttaaaaat
    11521 tccgtcatca taatcgaaac ttactaaccc acccaatcta tcaacggagg atttgatact
    11581 gtttatccct atgccgtgaa gcccttgttc tttctttgtt gatgttaaaa cagatgtatc
    11641 taccttatct gatgtatttg taatgacaat aaatagcttc tctcgttctt ccattaggct
    11701 tatccaaata tgcttatgtg atacaccagc tctctggcaa ccttctattg cattgtcaag
    11761 agcgtttccg atgatacggc acaactccaa ttcgtctgcc ttgatatttg ttatgatatt
    11821 gaccttgcaa ataaactcta taccgtatgt ctgagcaaga gaacccttga tgttcacaat
    11881 agaatcgacg gcattattac cagtatagca gagtctgtta gcaagcctta caaatgagct
    11941 tagcttgaca agatattcct tagcagaatc agtatcattg ttttccaaca tatcattcag
    12001 aactaaaaat tgattttcaa tatcgtgttt aaactctcgt acttgcttgt atgacagggt
    12061 aagcagctta tagttttcct gttcctgttg ctttattgtt tcaaggtatt ttaactttat
    12121 cttatcttca aaactttcaa agaaattaaa catagcaagg tttataaaga taattcctgc
    12181 aagagaaacg cccaaagaaa cataactata agtgttgctg ccaacaaatc catcaagcat
    12241 tgtttgtaaa agaaaaatac ttatgattgg aataactatt atcaatatcc aatattttat
    12301 cggcagttca cgaatttttt tgtttattat gcggtgcatc aatcctataa gccataaata
    12361 aattatattt gtgcctacca ttccgagata acgtcctaaa ccagactcta agaattcatc
    12421 tggtgttccc atattagcaa tgcaaagtaa tccaatcaca ataggttcag atatagatat
    12481 aatcagtaaa aacaatatgt tccaaaatat tttatgacgg attgaatcat cataacaaat
    12541 aaaggacatg gagctaataa gaataatggt tgtaatcaga tacactaaaa tattatctgt
    12601 caacaaaact gtcgctgaca gtattacagt agaaagaaga tacgacagat aaagaactgc
    12661 tttattaact tttgccttac tcaacaagga aaagtataag aataccaaca tcatttcaat
    12721 tgctacattg acaatctcaa tgatattttc aatcaatacg ggcaactcga tcatctccct
    12781 gttgcatagt taagatagcg agcaactatc tcatctttat atgttttgcc tatggggatt
    12841 tttctgccgt tgcttagaat aatatcgtac ttggtaatat tctgtatatg gtcaagattt
    12901 acaagtattc cacggtttat aatagcgaaa ttgtacttta acaactcgcc acacacagtt
    12961 gaaaaatcgc cgccgtactc caattcacca ttaactgtga atagtgatac ctttcttcta
    13021 tgtccctcaa agtaaagaat atctgtcagc ctgaacttga atgacagatt tttattattg
    13081 aaagtgaaag ttctaaatcg ctgctggcac tcagcaatga tagaatttag ctgtttggta
    13141 tatacatagt ctggctgatt tttcaatata tagcgaaacg ctcccacatc gtagccctta
    13201 acggcaaatt cggcataatt cgtcaggaaa gaaataataa ctgaaccatc tatctgtctg
    13261 attctttcag cggtctgcaa tccggtcaga tcgggcattt caacatcgag tatgatgact
    13321 tcatacattc ccttgacata gaaactcaat aagtctctcc cgcttgtaaa ttcgtgtatt
    13381 tcgcagtcgg ggagtttcat ttctcttaat ctgttatgaa gttgttttaa gaatacaggt
    13441 tcatcatcaa cgatagcaat attcatagca atcacctcac aattggtcat gctttatgta
    13501 tcagttatca ttataccaca tcggagagat tatttcaaga gaaaaaatag ctatgcctcc
    13561 attaatagtt tcggagacat agcctcatgt tgcgttattt tatattcatc gaatatggtc
    13621 tattgcctga tttaagagtg ggtgtactta taagtgcttc acagatactg tccacgatac
    13681 cacgaaactg cacgatttct tctttgcaga agctctctct aagctcaaag gcggcggaat
    13741 catggcattc gtgacctcgg caggcacact tgacaagcgt gatgagagtg tccgccagat
    13801 gttggctgac aagtctgatt tcatcggtgc gatcagactg ccgggtggaa agaacggtgc
    13861 atttaaggat aacgccggaa cagaggtcac aacggatatt atcttcctga aaaagcatga
    13921 aggcaagtca cttgccgaaa tgtccgatat tcccgattgg gttcatatcg gtgaaacggc
    13981 tgacggtctg ccgatcaaca aatactttga acagcactct gatatggtgc ttggtacagt
    14041 ggtcgagggt aataagctct acggcagcgg tactatggtt gtcgctgagg acggttttga
    14101 cctgagatcg gcgctccatg aagcggtcgg aaagctgtct gcggagatca gtcatgagcg
    14161 tggcagagat gtgtatgcga aaacggctga cggtgtgcag gtgcagattc catcgaaact
    14221 gcgtaattac agctttttcc tttctgacaa tcaggtcttc ttcaagaaaa ataatgctgc
    14281 ctgtgagttc cgttttgaca agggtactgc acagcacaag cgtttcaagg catttattga
    14341 gcttcgtgat ctcacccgtg agctgatcga agcaatggaa cttgacaagc ctgacagcgt
    14401 tattaaggat ttgcaggcaa agctgaatgt ggcatacgat gatttctaca agaagttcgg
    14461 gcttatccac tctcagacca acaagcgtta ttttgcggaa gatgtgtcct acaatcttgt
    14521 ggcaggactg gaaaagagct atgataagac taagctcctt gaaaagtccg atattttcac
    14581 aaagcggact atcgtgccga cgaatgctgt ggaacacgtt gatacagcac ttgaagcact
    14641 cacgctctcc attgcggaga aagcacgggt tgactttgag tacatgagtg gactgacagg
    14701 tatgaccgag gacgagttga agcacgacct gacgagcgag atcttcaaga ttccacatac
    14761 ggagaacgag tatcagacgg cttcggagta cctttcgggc gatattcgca agaaactccg
    14821 tgaagctgag gaaatcgctg agtatgatcc cgatttcaat atcaatgtat cggcgctgaa
    14881 acaggctatg cctgaaccgc tgaaagccgg agatattgac attaagctcg gtgctgcttg
    14941 gcttgatccg aaatactatg agcagttcat gtatgagctg ttgcagactc cggcatatca
    15001 gcggagtgac agtccgtctt cccgttggaa caagtctgct atcgtcggtg ttgagtattc
    15061 cgttcacgct aactctttcc atgtaagcaa caaatcttcc gacaggtcgg tgcttgcgac
    15121 tcagaagtac ggcacacaca agatgaacgc ttatgacatc tttgagcatt tgctgaatct
    15181 gcaagagccg aaggtctaca agacgatcga agtgccggac ggcttgggcg atacaaagga
    15241 aaagcgtgtg gtggatatag atgctacccg tgtcgtacag cgtaaagccg atgatattcg
    15301 caaagctttc aaggcgtgga tattcaaaga tccgcaacgc cgtgaagcta tcgtagagaa
    15361 gtataacgaa cttttcaaca gtatccgtcc ccgtgagttc gatggctcgg ctctttcctt
    15421 cccgatgatg acttcggata ttaagctcca cgaccatcaa aagaacgcaa tcgctcatgc
    15481 gatgtttggc ggtaatacgc tgtttgcaca ctgcgtgggt gcgggcaaaa cctttgaaat
    15541 gatcgcaacg gcgatggaaa gcaagcgatt aggtttgtgt actaagagcc tgtttgccgt
    15601 gccgaatcat ctgacggagc agatcggtga cgattttcag aagctctatc cgggagcaaa
    15661 tattcttgtt gctaccaaaa aggactttca gaaagcaaat cgtcagcagc tctttgcaaa
    15721 aatcgcaact ggaaactatg atgcggttat cataggtcac tctcagctcg gtaaaatccc
    15781 tgtttcaaag gagagacagg tcatgacgat ccagagtcag attgacgata ttctccgtgg
    15841 tatcgaggaa ctgaaaaaga gcgaaggctc taagtttcag atcaaggcta tggagcgtac
    15901 ccgtaaaagt ctgcaaaagc agcttgataa gctcgaaaag gctaatcagg acgatacgct
    15961 gacctttgaa caacttggta tagatcgctt gttcgtcgat gaagcccatg agtttaagaa
    16021 cctatttgtt gccacaaaat tgcagaatgt agccggaatt tccaattctg cttcgcaaaa
    16081 agcacttgat ttgttcctca aatgccgtta tctcgatgaa aagactggcg gcaaaggcgt
    16141 ggtttttgct actggaacgc ctctcagtaa cagcattaca gagcttcaca ccatgatgcg
    16201 gtatttggag tatgacttcc tgaacaatca cggattacag cactttgaca actgggtagc
    16261 agtctttgga gaccagaaaa ccgattggga gttaaagcct gcgggcaatg gcttcaagga
    16321 gcgtacccgt atcgccaatt atacaggtct gcccgaactg atgagtatgt ttaagcaggt
    16381 cgctgacatt cgtactgcgg atacgctgaa acttgatgtg cctgactgtg aatatcaggt
    16441 ggttcaagtc gaagccactc cgttccagca ggagcttgtt caagagcttg ccgacagagc
    16501 tgatgctatc aatgcaggca atgttgatcc cacgatcgac aatatgctca agatcacgtc
    16561 ggacggtagg aagcttggtc ttgatcctcg tctgattgat ccgtcatttg aagataaccc
    16621 cgatacaaag ctcaaccgct gtgtagagaa tgttgcccgt atccacgctg aaacggctga
    16681 ggacaggctc acgcagatca tcttctgtga tttgggcgtt ccgcacaagg caacaggaga
    16741 agcagaggcc gaggacgaag atgccgacga tgctaaagat aagaaattta ttgctgaggt
    16801 tgaatcattg gaggaagaat gcgatttttg cgtttatgac gatattcgtg acaagctgat
    16861 cgcaaggggt atccctgcgg aggaaattgc atacattcac gatgcgaaaa ctgaacagca
    16921 gaaatccgat ctttttgata aagtccgtaa tggtgagatt cgtgttctgc tcggttctac
    16981 ggcaaaaatg ggtacgggta ctaacgtaca gaaacggctt aaactcgctc cgtgacctca
    17041 gaccgctgtt gcgaaacttt cgctcgatcg cttcgtattc tgcttcggtg aggcgtatct
    17101 gcatataccg attatgtggt tcgatctctg ctatttttct catctccttc gttcggggtt
    17161 caaggggtgt ccctcttgca agcattgtat cgaaacattc aatttctgag aaattgtaat
    17221 gcggagatac cgagcttgct aggtttgaat cacgcccttc gtgcgtgact tcaatttgag
    17281 cctttggctc tgtaaagttt cctctctcag ttggaggaat tggagctttg cgacttcggc
    17341 tgcaataccc cctcacttat ttaccgccat attttaaaaa tcgggaaaga aatctgcaag
    17401 agttcacaaa aagtttacga ttgaatttgc tggtgataca gcattccgaa cgttatgccg
    17461 cttttttccg aacccgattg attctcgtgc ataattatgg taaaatgtta agagcaggtt
    17521 gtgtccttat cgctgtctga cagaagaaaa aatttcattt agggcgatgc gtgaacggga
    17581 taagtaaaac acaaaaatcc ctattctgaa acggaatcca gaacagggat tttcagcttt
    17641 tgcaggaggg aaaataaaat ggatcatgaa agaattatat acatctacga ttatctgtca
    17701 cggtacacag acgagaacca cgatgtatcg atcagccaaa tacaagaaca cctcgccaat
    17761 gtctgcaatc tgaccagggt gaagaacgta acgattcgcc gtgaccttga caggctgact
    17821 gctatgggaa atcatatcgt aaagcataac cgtgaacata acacagcata ctatgcttta
    17881 attgacaagg gtttctcatt caatgaaata cgtttcatcg ttgattcgat ctcgataaac
    17941 aaattcctga cagcatttca gaagaaaaca ctgataaaga aatttgaggg tatgtgttcc
    18001 gatgcagaga tcaggcagct catcagccgt atcgttctga atgaacgttg ttcctcgaca
    18061 ctcgatctct tggaaaactt ggataagatt catagattga tcggtgaacg gcagaaaata
    18121 gattttgaat acggcaagta tgacgaaaca acgaaacaga tagcttatta ctataagaaa
    18181 cggtaaatgc tccctgtgag cgtgatctac ttccatgagc gattctatct taaatgcctc
    18241 aatgagaagg acaggaaatg gcgtatatat agagttgacc gaatgaagaa tatcctcggt
    18301 ggcgaagtgt cttatgttcg gctgccacca gaggacaatt atgaggggtt cgtaacggat
    18361 atgtttgctc ctgaatactt caccgtagtc acactgcggg taaagaagta tctgctcgat
    18421 gaaatgaggg aaaattttga agattacgct tcgatccttc acgatgaaga tgctgactat
    18481 gttcgtatcc gtgtacgggt aggtatcaac cgcaaatttt atctgtggct tatgcagtat
    18541 ggtgacggtg tggagcttgt ttcgcctgca aaagaacgag ctgagtattt ggaagaagtc
    18601 cgtaaaatgc tcagagctta tcctgaattt gctgagtaac agctttgtga cggctctttc
    18661 tgcaactcac aagcaactct tgtgcaaccc cataattaat gatctgacgg taagctgtca
    18721 ttgttctcgg ataaacaggt tttgaatagc tttgagcgaa tcggagcata atgaaaggca
    18781 gtcggtagca atgtcggttg ttttctttct gccgattgac ctttccgttc cgttgtggta
    18841 taattaacct ataatctgct ttgctttgga gtgatacgat atggcagtct acatagtctt
    18901 tgacgttgaa acgcccaatc gttcaaatga ccgtatgagt gcgataggca tttctgcaat
    18961 caaggataat aagatcgtgg cgaactactt ttctcttgtt gatcccgaaa cacacttcga
    19021 ctacttcaac actaagctca ccggaataga tgcggataag gtcaagggcg ctccgaattt
    19081 tgcagagcta tggaagaaga ttgatcctat catgagcaag ggtatcctcg ttgcacataa
    19141 tgctgtgttc aatatgagcg ttcttcgtgc ctgtctgcgt gattacggta tctcttggaa
    19201 accgacggca aaataccttt gtatggtccg gatcggcagg cgtgttctgc ctgatatgaa
    19261 gcataaccta aacgtgatgt gcgatcacta cggtattgct ctcgatcatc atcaggcaga
    19321 cagtgatagt catgcctgtg cggagatact gctgagatat atcgaaagcg gtattgacgt
    19381 gagagaatat gtgaaagaat acaaactata aatcatcaat tatcagagct gttgcgataa
    19441 agcaatggct cttttctttt cagaattaca aattctatct atcttaaatg atataataaa
    19501 aaatgaaagt ttgtttccag aaagccaaat tttgtacaac tggtttcata taatggaagc
    19561 agacaagcat ataactcgat acttttgtga tgtcattgaa cagttccata caagacttga
    19621 tcggtaatcc attacggtct ttagggggtg atagctgtgt actggacgat gataatagat
    19681 cacggtctgc attgattgcc ttgcggattt gtttgtgctg atacagaagt tgagtgtgtt
    19741 atgctgtaaa ctctcggtat aaagggcggt ctgagcagat caggccgtcc tttttcttat
    19801 gcctaatgtg ataggaagat gaaattttgg tgaaaagttg ccgcactatg gctttgaacg
    19861 aagggttagt tttcaatagt gggacagagg tttgaatgag ttaggtgaaa atgttggatt
    19921 ggtagtgcat tatcaaaaag tgcaggaaaa tggggctttt ataaaaatcg ggtgctcccg
    19981 aacgggaacg ccaagaagtt gctttttatg ctgtaatagt tcataataat aatataaaac
    20041 gcattggtgc gtttctccaa cggtgaacct tactgcgcag gggctactcg atcactgtat
    20101 ggaaactgaa catcaaacaa tcgaatggac gagtaatgtt tgattgtcgg acgggtatat
    20161 tccgaatgac aggcttacta tgttcatttg ctgatttccg tccgacagaa aggacggaac
    20221 cagtatgata aatgatttac atactcctca gattctatta tttagcgaac aggaggagcc
    20281 gcaaagctac gaaatttacg tttacggaac tgatgatctt gttgagcagc ataaggacag
    20341 cttctgctta gcattatgtc ggtatttaga cgagatccat ataagccaga aaacgctggc
    20401 aaggttgaca gggattgctc cctctacact ctcacggtat ctttcgggga aaagaaagat
    20461 gcagtatgac tgcctctgtg cggtctgtat cgcacttaga cttcaccctt gcaggcagcg
    20521 ttatttgttt tcgctcctga tgtatgcgtt gccatgttat caggatttca gaaaagcaga
    20581 taagaacatc atcatggcgt atcttgacgg ctgtgcgttc aataaccgtt atacgctgac
    20641 agcctgcaat gaacagttga aggcaatcca tgccaaacct cttacacacc tgacctctgc
    20701 taagggtgac agtgtgtaat gggaagattt atgtatgtcc actttggcga tgatgttccc
    20761 cgtaatattg agaaagagta taacaagctc ttgcgaaaag aacgatacct tgaggagcga
    20821 gatgcagaaa acggaatgat ctatgccgat tttgacgctg ttcttgctgc aaatcccgat
    20881 cctgcaagta tcccaataag cgaggaagaa gagcaggagc agatcaggca acggaacagg
    20941 catgactatc tgcctgatgc cttagaactt ttgaaatcgg attttcctga agggtatgag
    21001 ctgatacggg attactttct gagagaggac aaggtgacga tgtggtatct cgttgagaaa
    21061 tacggcttgt ccattgatgt ggtgcgttat cgaatcaaga tcgcaaagca gaagctcaaa
    21121 gagtatatta tcttgcacga aaatgaatga ataaatatgt gcagaacgct gattttttct
    21181 ttttggagaa agaaatatgg gaaaaacttt cccgattttg caaaatcctc ggttgatata
    21241 tagaggggtt cataccactg acgtttgata agggtacgga tcacttgctg acataactat
    21301 cctctgtgat aagggacggt acggtttttc catttgccgc acagtcccct tagctt
//
