LOCUS       NC_021039.1            21476 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_021039.1 Ruminococcus champanellensis 18P13 = JCM 17042, complete
            sequence.
ACCESSION   NC_021039
VERSION     NC_021039.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:21:20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1566659
            Orig. end    :: 1588135
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21476
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[1576659:1578135]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11476
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21476
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21476
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="3"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     YcaO or TIGR03882)))"
                     /tool="antismash"
     CDS             261..992
                     /locus_tag="ctg1_1377"
                     /transl_table=11
                     /translation="MKTTHKSNLMKLVMLAMLVAIGVVISPILRVEGMCPMAHFINIVC
                     AVLLGPWYSLLCAVLIGIIRMAFMGIPPLALTGAVFGAFLSGMFYRLSKGKLIAAFLGE
                     VFGTGIIGAIVSYPVMTYLVGRTGLTWFFYVPSFISGTLIGGSLAFVFLRALAKNGQLA
                     RFQTALGSVSYAVSSDVWSNAVGIAALGLIGYLASVVLLKMLLKLSGTWVTVVPYALVG
                     AALLAAVIYLIRNRSQLRQQA"
     aSDomain        291..740
                     /aSDomain="TIGR02359"
                     /aSTool="tigrfam"
                     /description="thiW: energy coupling factor transporter S
                     component ThiW"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1377_0020"
                     /evalue="6.80E-42"
                     /identifier="TIGR02359"
                     /label="ctg1_1377"
                     /locus_tag="ctg1_1377"
                     /protein_end="160"
                     /protein_start="10"
                     /score="141.2"
                     /tool="antismash"
                     /translation="KLVMLAMLVAIGVVISPILRVEGMCPMAHFINIVCAVLLGPWYSL
                     LCAVLIGIIRMAFMGIPPLALTGAVFGAFLSGMFYRLSKGKLIAAFLGEVFGTGIIGAI
                     VSYPVMTYLVGRTGLTWFFYVPSFISGTLIGGSLAFVFLRALAKNG"
     PFAM_domain     294..734
                     /aSDomain="ThiW"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09512.12"
                     /description="Thiamine-precursor transporter protein
                     (ThiW)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1377_0091"
                     /evalue="1.20E-46"
                     /label="ctg1_1377"
                     /locus_tag="ctg1_1377"
                     /protein_end="158"
                     /protein_start="11"
                     /score="158.6"
                     /tool="antismash"
                     /translation="LVMLAMLVAIGVVISPILRVEGMCPMAHFINIVCAVLLGPWYSLL
                     CAVLIGIIRMAFMGIPPLALTGAVFGAFLSGMFYRLSKGKLIAAFLGEVFGTGIIGAIV
                     SYPVMTYLVGRTGLTWFFYVPSFISGTLIGGSLAFVFLRALAK"
     CDS             1005..1811
                     /locus_tag="ctg1_1378"
                     /transl_table=11
                     /translation="MKKRICMLLEQLRQKQPLVHCITNPISINDCANALLAVGARPMMA
                     EHPREVAGITAHAGALLLNLGNITDVRMESMQLAGQAAMQAKVPVILDLVGVACSDLRR
                     EFALHLLEQMHPAVLRGNRTEIRAMQEQIHADGVDVSREDAADTGAYLNAARQLAARYD
                     TVVLTSGAADDVTDGQKHVRVLGGTELLSHVTGTGCMQGALIAAYLAVGAPLEAAVCGA
                     AVLDAAASAVLPGVSGPGSLRSALADGLWNLSPEQLCKYCEIEEQL"
     PFAM_domain     1029..1772
                     /aSDomain="HK"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02110.17"
                     /description="Hydroxyethylthiazole kinase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1378_0092"
                     /evalue="2.10E-61"
                     /label="ctg1_1378"
                     /locus_tag="ctg1_1378"
                     /protein_end="256"
                     /protein_start="8"
                     /score="207.5"
                     /tool="antismash"
                     /translation="LEQLRQKQPLVHCITNPISINDCANALLAVGARPMMAEHPREVAG
                     ITAHAGALLLNLGNITDVRMESMQLAGQAAMQAKVPVILDLVGVACSDLRREFALHLLE
                     QMHPAVLRGNRTEIRAMQEQIHADGVDVSREDAADTGAYLNAARQLAARYDTVVLTSGA
                     ADDVTDGQKHVRVLGGTELLSHVTGTGCMQGALIAAYLAVGAPLEAAVCGAAVLDAAAS
                     AVLPGVSGPGSLRSALADGLWNLSPE"
     CDS             1808..2458
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280:thiamine-phosphate pyrophosphorylase (Score:
                     182.6; E-value: 8.9e-56)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1379"
                     /transl_table=11
                     /translation="MKFDPTLYLVTDSSLYEEDAFLSVIDGVCSAGITLLQLREKERST
                     REYLRLARVVRQITDRYGIPLILDDRADVAAACGCAGVHVGQEDLPVEDARRILGADKI
                     VGATAKTLEQARIAYAQGADYLGCGAVYPTTTKVRTVLTPVETIRQICESVPIPVNAIG
                     GLNRGNLEILRGVPIRGVCVVSAIMKAADPALETRLLKEAVRTLLEDAPCAAH"
     PFAM_domain     1826..2368
                     /aSDomain="TMP-TENI"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02581.19"
                     /description="Thiamine monophosphate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1379_0093"
                     /evalue="1.50E-57"
                     /label="ctg1_1379"
                     /locus_tag="ctg1_1379"
                     /protein_end="187"
                     /protein_start="6"
                     /score="193.9"
                     /tool="antismash"
                     /translation="LYLVTDSSLYEEDAFLSVIDGVCSAGITLLQLREKERSTREYLRL
                     ARVVRQITDRYGIPLILDDRADVAAACGCAGVHVGQEDLPVEDARRILGADKIVGATAK
                     TLEQARIAYAQGADYLGCGAVYPTTTKVRTVLTPVETIRQICESVPIPVNAIGGLNRGN
                     LEILRGVPIRGVCVVSAI"
     aSDomain        1826..2398
                     /aSDomain="TIGR00693"
                     /aSTool="tigrfam"
                     /description="thiE: thiamine-phosphate diphosphorylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1379_0021"
                     /evalue="2.10E-60"
                     /identifier="TIGR00693"
                     /label="ctg1_1379"
                     /locus_tag="ctg1_1379"
                     /protein_end="197"
                     /protein_start="6"
                     /score="201.4"
                     /tool="antismash"
                     /translation="LYLVTDSSLYEEDAFLSVIDGVCSAGITLLQLREKERSTREYLRL
                     ARVVRQITDRYGIPLILDDRADVAAACGCAGVHVGQEDLPVEDARRILGADKIVGATAK
                     TLEQARIAYAQGADYLGCGAVYPTTTKVRTVLTPVETIRQICESVPIPVNAIGGLNRGN
                     LEILRGVPIRGVCVVSAIMKAADPALET"
     CDS             2443..3216
                     /locus_tag="ctg1_1380"
                     /transl_table=11
                     /translation="VRCALTIAGSDSGGGAGIQADLKTFAAHHLYGASVITAVTAQNTL
                     GVRESYPLPPEIVAAQLSAVLEDLHPAAIKIGMLGNGDIVRTVSRVLAQYPDVPVVLDP
                     IMLSTSGHPLLDPEGVSAMEQLLFPRAALITPNLPEAQALTGLPLSDLHAVKAAAQLLY
                     RTYGCGVLIKGGHSAGEPVDVLYDGSLHVFTGKRIPGRDVHGTGCTLSSAIAAGLAQGM
                     ALPEAVQGAKRYLSCAMESAFSVGCGAPVLNHFLS"
     aSDomain        2452..3207
                     /aSDomain="TIGR00097"
                     /aSTool="tigrfam"
                     /description="HMP-P_kinase: hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1380_0022"
                     /evalue="4.90E-91"
                     /identifier="TIGR00097"
                     /label="ctg1_1380"
                     /locus_tag="ctg1_1380"
                     /protein_end="255"
                     /protein_start="3"
                     /score="302.5"
                     /tool="antismash"
                     /translation="ALTIAGSDSGGGAGIQADLKTFAAHHLYGASVITAVTAQNTLGVR
                     ESYPLPPEIVAAQLSAVLEDLHPAAIKIGMLGNGDIVRTVSRVLAQYPDVPVVLDPIML
                     STSGHPLLDPEGVSAMEQLLFPRAALITPNLPEAQALTGLPLSDLHAVKAAAQLLYRTY
                     GCGVLIKGGHSAGEPVDVLYDGSLHVFTGKRIPGRDVHGTGCTLSSAIAAGLAQGMALP
                     EAVQGAKRYLSCAMESAFSVGCGAPVLNHF"
     PFAM_domain     2473..3189
                     /aSDomain="Phos_pyr_kin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08543.14"
                     /description="Phosphomethylpyrimidine kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1380_0094"
                     /evalue="5.90E-88"
                     /label="ctg1_1380"
                     /locus_tag="ctg1_1380"
                     /protein_end="249"
                     /protein_start="10"
                     /score="294.5"
                     /tool="antismash"
                     /translation="DSGGGAGIQADLKTFAAHHLYGASVITAVTAQNTLGVRESYPLPP
                     EIVAAQLSAVLEDLHPAAIKIGMLGNGDIVRTVSRVLAQYPDVPVVLDPIMLSTSGHPL
                     LDPEGVSAMEQLLFPRAALITPNLPEAQALTGLPLSDLHAVKAAAQLLYRTYGCGVLIK
                     GGHSAGEPVDVLYDGSLHVFTGKRIPGRDVHGTGCTLSSAIAAGLAQGMALPEAVQGAK
                     RYLSCAMESAFSVGCGA"
     CDS             complement(3287..5389)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CBM_48"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297:Pullulanase, type I (Score: 525.9; E-value:
                     3.3e-159)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1381"
                     /sec_met_domain="CBM_48 (E-value: 1.3e-08, bitscore: 32.1,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Alpha-amylase (E-value: 7.3e-19, bitscore:
                     65.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVITNMPLIPVDTISGFPVRPGNHLIQGATAMPNAVNFTISSAN
                     ATSCELLLFHRKEKTPYAVIPIPDSYRIGDVFSIIVFGLDITEFEYAYRMDGPHDPRKG
                     LLFNKERILLDPYARAVTGQHEWGENAANDHQYHARVVTESFDWGDMRSPELPLRDLII
                     YEMHVRGFTRSSTSGVAHPGTFAGILEKLPHLLALGINAVELMPVFEFNELEDARVIDG
                     KTLYNYWGYNTVSFFSPNTSYSSENEYNREGNELKQMIRVLHEHGIEVILDVVFNHTAE
                     GNEQGSAFSFKGIDNNVYYMLTPDGSYFNFSGCGNTFNCNHPVVQQFILNCLRYWATEY
                     RIDGFRFDLAAIMGRNEDGSPMRNPPLLRNLAYDPVLSKVKLIAEAWDAGGLYQVGSFS
                     SLRRWAEWNGRYRDDLRCFLKGDADMAQAAINRITGSTDLYDPVYRGDNASVNFLTCHD
                     GFTLYDLYAYNTKHNEANGWNNTDGDNCGNSWNCGAEGDTDNQEIRALRMRLIKNAFAT
                     LLCSRGAAMFLAGDEFCNTQFGNNNPYCQDNEVSWLDWSLLEKNQEIFRFCRDMIALRK
                     AHPCITENLEPASTNFPAVSIHNAFPWHTDCHPDTRVIGILFSGKHPKTGADDMVFLGI
                     NTFWENQKIQMPDLPEHLYWHIACNTALPHADPPIYQTQSSWEGCTNIWAAPRSVIVAY
                     ARVKGT"
     aSDomain        complement(3401..5320)
                     /aSDomain="TIGR02100"
                     /aSTool="tigrfam"
                     /description="glgX_debranch: glycogen debranching enzyme
                     GlgX"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1381_0023"
                     /evalue="4.50E-193"
                     /identifier="TIGR02100"
                     /label="ctg1_1381"
                     /locus_tag="ctg1_1381"
                     /protein_end="663"
                     /protein_start="23"
                     /score="641.0"
                     /tool="antismash"
                     /translation="NHLIQGATAMPNAVNFTISSANATSCELLLFHRKEKTPYAVIPIP
                     DSYRIGDVFSIIVFGLDITEFEYAYRMDGPHDPRKGLLFNKERILLDPYARAVTGQHEW
                     GENAANDHQYHARVVTESFDWGDMRSPELPLRDLIIYEMHVRGFTRSSTSGVAHPGTFA
                     GILEKLPHLLALGINAVELMPVFEFNELEDARVIDGKTLYNYWGYNTVSFFSPNTSYSS
                     ENEYNREGNELKQMIRVLHEHGIEVILDVVFNHTAEGNEQGSAFSFKGIDNNVYYMLTP
                     DGSYFNFSGCGNTFNCNHPVVQQFILNCLRYWATEYRIDGFRFDLAAIMGRNEDGSPMR
                     NPPLLRNLAYDPVLSKVKLIAEAWDAGGLYQVGSFSSLRRWAEWNGRYRDDLRCFLKGD
                     ADMAQAAINRITGSTDLYDPVYRGDNASVNFLTCHDGFTLYDLYAYNTKHNEANGWNNT
                     DGDNCGNSWNCGAEGDTDNQEIRALRMRLIKNAFATLLCSRGAAMFLAGDEFCNTQFGN
                     NNPYCQDNEVSWLDWSLLEKNQEIFRFCRDMIALRKAHPCITENLEPASTNFPAVSIHN
                     AFPWHTDCHPDTRVIGILFSGKHPKTGADDMVFLGINTFWENQKIQMPDLPEHLYWHIA
                     CNTAL"
     PFAM_domain     complement(4511..4843)
                     /aSDomain="Alpha-amylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00128.26"
                     /description="Alpha amylase, catalytic domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1381_0096"
                     /evalue="2.60E-12"
                     /label="ctg1_1381"
                     /locus_tag="ctg1_1381"
                     /protein_end="293"
                     /protein_start="182"
                     /score="47.1"
                     /tool="antismash"
                     /translation="GTFAGILEKLPHLLALGINAVELMPVFEFNELEDARVIDGKTLYN
                     YWGYNTVSFFSPNTSYSSENEYNREGNELKQMIRVLHEHGIEVILDVVFNHTAEGNEQG
                     SAFSFKG"
     PFAM_domain     complement(5036..5305)
                     /aSDomain="CBM_48"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02922.20"
                     /description="Carbohydrate-binding module 48 (Isoamylase
                     N-terminal domain)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1381_0095"
                     /evalue="8.10E-09"
                     /label="ctg1_1381"
                     /locus_tag="ctg1_1381"
                     /protein_end="118"
                     /protein_start="28"
                     /score="35.8"
                     /tool="antismash"
                     /translation="GATAMPNAVNFTISSANATSCELLLFHRKEKTPYAVIPIPDSYRI
                     GDVFSIIVFGLDITEFEYAYRMDGPHDPRKGLLFNKERILLDPYA"
     CDS             5528..5881
                     /locus_tag="ctg1_1382"
                     /transl_table=11
                     /translation="MKIQIFGKAKSFDTKKAERYFKERGIPFQSVDILRKGLSRGELDS
                     VLRAVGGLEAVIDDTAKDYCMIKYLLEDAKLEKLMEQPSLYRTPIVRNGRQATVGYCPE
                     IWKQWEEAERHAM"
     PFAM_domain     5741..5848
                     /aSDomain="ArsC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03960.17"
                     /description="ArsC family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1382_0097"
                     /evalue="2.60E-04"
                     /label="ctg1_1382"
                     /locus_tag="ctg1_1382"
                     /protein_end="107"
                     /protein_start="71"
                     /score="21.1"
                     /tool="antismash"
                     /translation="EDAKLEKLMEQPSLYRTPIVRNGRQATVGYCPEIWK"
     CDS             5871..6041
                     /locus_tag="ctg1_1383"
                     /transl_table=11
                     /translation="MQCESCVYYVYDEELDCYSCLVELDEDEYGRFLRGECRSCPYYRL
                     DDEYGVVRHQM"
     PFAM_domain     5874..6038
                     /aSDomain="DUF6472"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF20076.1"
                     /description="Domain of unknown function (DUF6472)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1383_0098"
                     /evalue="6.30E-25"
                     /label="ctg1_1383"
                     /locus_tag="ctg1_1383"
                     /protein_end="56"
                     /protein_start="1"
                     /score="87.2"
                     /tool="antismash"
                     /translation="QCESCVYYVYDEELDCYSCLVELDEDEYGRFLRGECRSCPYYRLD
                     DEYGVVRHQM"
     CDS             6051..6533
                     /locus_tag="ctg1_1384"
                     /transl_table=11
                     /translation="MGKEVKTNAMRILDRLKLPYTLNSYECKEFIDGVHIADMLGQDPA
                     QSFKTLVCSGKGGGYYVFVLPVARELDLKKAARAVGAKAVELLPVKEINAVTGYIRGGC
                     TAIGMKKQYPTVIDQSAGEFDRIIISGGRIGSQIFLAPDDFIKATGGSYGDILAEM"
     aSDomain        6069..6518
                     /aSDomain="TIGR00011"
                     /aSTool="tigrfam"
                     /description="YbaK_EbsC: Cys-tRNA(Pro) deacylase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1384_0024"
                     /evalue="1.80E-50"
                     /identifier="TIGR00011"
                     /label="ctg1_1384"
                     /locus_tag="ctg1_1384"
                     /protein_end="156"
                     /protein_start="6"
                     /score="168.7"
                     /tool="antismash"
                     /translation="TNAMRILDRLKLPYTLNSYECKEFIDGVHIADMLGQDPAQSFKTL
                     VCSGKGGGYYVFVLPVARELDLKKAARAVGAKAVELLPVKEINAVTGYIRGGCTAIGMK
                     KQYPTVIDQSAGEFDRIIISGGRIGSQIFLAPDDFIKATGGSYGDI"
     PFAM_domain     6159..6491
                     /aSDomain="tRNA_edit"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04073.17"
                     /description="Aminoacyl-tRNA editing domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1384_0099"
                     /evalue="6.20E-23"
                     /label="ctg1_1384"
                     /locus_tag="ctg1_1384"
                     /protein_end="147"
                     /protein_start="36"
                     /score="81.3"
                     /tool="antismash"
                     /translation="ADMLGQDPAQSFKTLVCSGKGGGYYVFVLPVARELDLKKAARAVG
                     AKAVELLPVKEINAVTGYIRGGCTAIGMKKQYPTVIDQSAGEFDRIIISGGRIGSQIFL
                     APDDFIK"
     CDS             6702..7532
                     /locus_tag="ctg1_1385"
                     /transl_table=11
                     /translation="MFRIVQKRVLNDAVVLMEFEAPYIAKKAQAGQFIIFRIDEQGERI
                     PLTIADYDRENGTITIIFQIVGKSTQHLATLNEGDTILDLVGPLGVPTHLDPDVKRVCV
                     VGGGVGCAIAYPQAKALHSRGIYVDVIAGFRSKDIVILEDEFKAVCNELVLCTDDGSYG
                     KKGFVTNALQELIDAGRNYDAVIAIGPVPMMKFVCKVTEPYNLKTIVSLNPIMIDGTGM
                     CGGCRVTVGGKIRYACVEGPDFDGHQVDFDELMRRNGTYREYEQHCRLMAQAEK"
     PFAM_domain     7341..7451
                     /aSDomain="DHODB_Fe-S_bind"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10418.11"
                     /description="Iron-sulfur cluster binding domain of
                     dihydroorotate dehydrogenase B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1385_0100"
                     /evalue="1.00E-11"
                     /label="ctg1_1385"
                     /locus_tag="ctg1_1385"
                     /protein_end="250"
                     /protein_start="213"
                     /score="44.5"
                     /tool="antismash"
                     /translation="PIMIDGTGMCGGCRVTVGGKIRYACVEGPDFDGHQVD"
     CDS             7612..8967
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176:alkyl hydroperoxide reductase subunit (Score:
                     71.9; E-value: 7.1e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1386"
                     /transl_table=11
                     /translation="MPEQKPEVRARNFQEVTLGYSKAMAMEEASRCLNCKNKPCVSGCP
                     VGVRIPEFIACVAAGDFDKAYDIITSTNGLPAVCGRVCPQEHQCESKCVRGIKGEPVGI
                     GRLERFVADYKMEQGNTKVEVPASNGHKVAVVGAGPSGLTCAGDLARLGYQVTVFEAFH
                     VAGGVLMYGIPEFRLPKAIVQKEIKTLKALGVNIMTDMVIGKVLSVDELLEDGYEAIFI
                     GSGAGLPRFMGIEGEALVGVCSANEYLTRINLMKGYLEEYDTPVIKSKRVAVVGGGNVA
                     MDAARSAMRMGAEHVYIVYRRSEEEMPARKEEVHHAKEEGIEFLNLNNPVKIIGDENGR
                     VCAMECIRMELGEPDESGRRSPIPVEGSNYNLEVDTVIMSIGTSPNPLIRTTTSGLEAN
                     KRGCLIVDEAMCTTKEGVYAGGDAVTGAATVILAMGAGKTAAQSIDKYIQNK"
     aSDomain        7627..8955
                     /aSDomain="TIGR01316"
                     /aSTool="tigrfam"
                     /description="gltA: glutamate synthase (NADPH),
                     homotetrameric"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1386_0025"
                     /evalue="2.40E-178"
                     /identifier="TIGR01316"
                     /label="ctg1_1386"
                     /locus_tag="ctg1_1386"
                     /protein_end="448"
                     /protein_start="5"
                     /score="591.5"
                     /tool="antismash"
                     /translation="PEVRARNFQEVTLGYSKAMAMEEASRCLNCKNKPCVSGCPVGVRI
                     PEFIACVAAGDFDKAYDIITSTNGLPAVCGRVCPQEHQCESKCVRGIKGEPVGIGRLER
                     FVADYKMEQGNTKVEVPASNGHKVAVVGAGPSGLTCAGDLARLGYQVTVFEAFHVAGGV
                     LMYGIPEFRLPKAIVQKEIKTLKALGVNIMTDMVIGKVLSVDELLEDGYEAIFIGSGAG
                     LPRFMGIEGEALVGVCSANEYLTRINLMKGYLEEYDTPVIKSKRVAVVGGGNVAMDAAR
                     SAMRMGAEHVYIVYRRSEEEMPARKEEVHHAKEEGIEFLNLNNPVKIIGDENGRVCAME
                     CIRMELGEPDESGRRSPIPVEGSNYNLEVDTVIMSIGTSPNPLIRTTTSGLEANKRGCL
                     IVDEAMCTTKEGVYAGGDAVTGAATVILAMGAGKTAAQSIDKYI"
     PFAM_domain     7636..7968
                     /aSDomain="Fer4_20"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14691.8"
                     /description="Dihydroprymidine dehydrogenase domain II,
                     4Fe-4S cluster"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1386_0101"
                     /evalue="2.80E-44"
                     /label="ctg1_1386"
                     /locus_tag="ctg1_1386"
                     /protein_end="119"
                     /protein_start="8"
                     /score="149.6"
                     /tool="antismash"
                     /translation="RARNFQEVTLGYSKAMAMEEASRCLNCKNKPCVSGCPVGVRIPEF
                     IACVAAGDFDKAYDIITSTNGLPAVCGRVCPQEHQCESKCVRGIKGEPVGIGRLERFVA
                     DYKMEQG"
     PFAM_domain     8002..8916
                     /aSDomain="Pyr_redox_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07992.16"
                     /description="Pyridine nucleotide-disulphide
                     oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1386_0102"
                     /evalue="4.80E-37"
                     /label="ctg1_1386"
                     /locus_tag="ctg1_1386"
                     /protein_end="435"
                     /protein_start="130"
                     /score="127.9"
                     /tool="antismash"
                     /translation="HKVAVVGAGPSGLTCAGDLARLGYQVTVFEAFHVAGGVLMYGIPE
                     FRLPKAIVQKEIKTLKALGVNIMTDMVIGKVLSVDELLEDGYEAIFIGSGAGLPRFMGI
                     EGEALVGVCSANEYLTRINLMKGYLEEYDTPVIKSKRVAVVGGGNVAMDAARSAMRMGA
                     EHVYIVYRRSEEEMPARKEEVHHAKEEGIEFLNLNNPVKIIGDENGRVCAMECIRMELG
                     EPDESGRRSPIPVEGSNYNLEVDTVIMSIGTSPNPLIRTTTSGLEANKRGCLIVDEAMC
                     TTKEGVYAGGDAVTGAATVILAMG"
     CDS             8988..9410
                     /locus_tag="ctg1_1387"
                     /transl_table=11
                     /translation="MFTSLHTFAAEQSATSGGAYGLVGILPWVIVLVALYFIMIRPQRK
                     KEKETIRMRSNIQIGDEILTIGGIVGIVVRKGEDTVVIETGGDRSKLRIRIEAVQENLT
                     AQEEAAKEKKEKQNAKLTPGAPKKEKPKKEKSESEE"
     aSDomain        9051..9290
                     /aSDomain="TIGR00739"
                     /aSTool="tigrfam"
                     /description="yajC: preprotein translocase, YajC subunit"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1387_0026"
                     /evalue="8.70E-20"
                     /identifier="TIGR00739"
                     /label="ctg1_1387"
                     /locus_tag="ctg1_1387"
                     /protein_end="101"
                     /protein_start="21"
                     /score="68.6"
                     /tool="antismash"
                     /translation="LVGILPWVIVLVALYFIMIRPQRKKEKETIRMRSNIQIGDEILTI
                     GGIVGIVVRKGEDTVVIETGGDRSKLRIRIEAVQE"
     PFAM_domain     9060..9284
                     /aSDomain="YajC"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02699.17"
                     /description="Preprotein translocase subunit"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1387_0103"
                     /evalue="9.30E-22"
                     /label="ctg1_1387"
                     /locus_tag="ctg1_1387"
                     /protein_end="99"
                     /protein_start="24"
                     /score="76.8"
                     /tool="antismash"
                     /translation="ILPWVIVLVALYFIMIRPQRKKEKETIRMRSNIQIGDEILTIGGI
                     VGIVVRKGEDTVVIETGGDRSKLRIRIEAV"
     CDS             9464..9868
                     /locus_tag="ctg1_1388"
                     /transl_table=11
                     /translation="MSRRTRRAAPWYRKYWLAIAGGLLLCIGILSLGALAASLADLPRW
                     VMNSLVLAALGCGAYLTGLLAGRRHRRHGLRNGGLLGVLLGICVLGISTACTGHVPHLH
                     ALVRLVWMAVCGGAGGVQGVNQKQPGVPEE"
     PFAM_domain     9518..9832
                     /aSDomain="DUF3792"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12670.9"
                     /description="Protein of unknown function (DUF3792)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1388_0104"
                     /evalue="1.20E-10"
                     /label="ctg1_1388"
                     /locus_tag="ctg1_1388"
                     /protein_end="123"
                     /protein_start="18"
                     /score="41.7"
                     /tool="antismash"
                     /translation="IAGGLLLCIGILSLGALAASLADLPRWVMNSLVLAALGCGAYLTG
                     LLAGRRHRRHGLRNGGLLGVLLGICVLGISTACTGHVPHLHALVRLVWMAVCGGAGGVQ
                     G"
     aSDomain        9518..9838
                     /aSDomain="TIGR04086"
                     /aSTool="tigrfam"
                     /description="TIGR04086_membr: putative membrane protein,
                     TIGR04086 family"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1388_0027"
                     /evalue="1.20E-12"
                     /identifier="TIGR04086"
                     /label="ctg1_1388"
                     /locus_tag="ctg1_1388"
                     /protein_end="125"
                     /protein_start="18"
                     /score="45.9"
                     /tool="antismash"
                     /translation="IAGGLLLCIGILSLGALAASLADLPRWVMNSLVLAALGCGAYLTG
                     LLAGRRHRRHGLRNGGLLGVLLGICVLGISTACTGHVPHLHALVRLVWMAVCGGAGGVQ
                     GVN"
     CDS             10001..10138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1389"
                     /sec_met_domain="TIGR03973 (E-value: 2.9e-24, bitscore:
                     81.8, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 6.4e-25, bitscore: 84.0,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHIQTINKANLKETAKKGGCGKCQASCQSACKTSCTVANQKCEK
                     "
     aSDomain        10004..10132
                     /aSDomain="TIGR03973"
                     /aSTool="tigrfam"
                     /description="six_Cys_in_45: six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1389_0028"
                     /evalue="5.50E-24"
                     /identifier="TIGR03973"
                     /label="ctg1_1389"
                     /locus_tag="ctg1_1389"
                     /protein_end="44"
                     /protein_start="1"
                     /score="81.8"
                     /tool="antismash"
                     /translation="KHIQTINKANLKETAKKGGCGKCQASCQSACKTSCTVANQKCE"
     PFAM_domain     10004..10135
                     /aSDomain="SCIFF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13165.8"
                     /description="Six-cysteine peptide SCIFF"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1389_0105"
                     /evalue="4.80E-24"
                     /label="ctg1_1389"
                     /locus_tag="ctg1_1389"
                     /protein_end="45"
                     /protein_start="1"
                     /score="84.1"
                     /tool="antismash"
                     /translation="KHIQTINKANLKETAKKGGCGKCQASCQSACKTSCTVANQKCEK"
     CDS             10241..11476
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1390"
                     /sec_met_domain="PF04055 (E-value: 5.2e-15, bitscore: 53.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.5e-14, bitscore: 50.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.8e-27,
                     bitscore: 92.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHKFKLNGFNIVLDVNSGGVHVVDELTYDLLDNVQPPFAPECPQ
                     EVVSKLTRFYAPEDIRSCYEEILELYKDKILFSEDDYEKFAKYSVAAPVKAMCLHIAHD
                     CNLRCEYCFASTGDFGKGRKLMPLEIGKKAIDFLLEQSRDRETLELDFFGGEPLMNFDV
                     VKEVVKYARSKEQEYGKRFRFTITTNGMLLTDDKIDFINKEMSNVVLSLDGRREVNDRV
                     RKRVDGTGCYDRILPAFQKLVAQRGDKDYYVRGTFTKYNLDFSDDVFSLYDAGFDQISV
                     EPVVSDPAKPYALTERELSDIFCEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXSGSTSSTL"
     aSDomain        10244..11155
                     /aSDomain="TIGR03974"
                     /aSTool="tigrfam"
                     /description="rSAM_six_Cys: SCIFF radical SAM maturase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1390_0029"
                     /evalue="2.10E-136"
                     /identifier="TIGR03974"
                     /label="ctg1_1390"
                     /locus_tag="ctg1_1390"
                     /protein_end="305"
                     /protein_start="1"
                     /score="453.3"
                     /tool="antismash"
                     /translation="IHKFKLNGFNIVLDVNSGGVHVVDELTYDLLDNVQPPFAPECPQE
                     VVSKLTRFYAPEDIRSCYEEILELYKDKILFSEDDYEKFAKYSVAAPVKAMCLHIAHDC
                     NLRCEYCFASTGDFGKGRKLMPLEIGKKAIDFLLEQSRDRETLELDFFGGEPLMNFDVV
                     KEVVKYARSKEQEYGKRFRFTITTNGMLLTDDKIDFINKEMSNVVLSLDGRREVNDRVR
                     KRVDGTGCYDRILPAFQKLVAQRGDKDYYVRGTFTKYNLDFSDDVFSLYDAGFDQISVE
                     PVVSDPAKPYALTERELSDIFCE"
     PFAM_domain     10532..10897
                     /aSDomain="Fer4_12"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13353.8"
                     /description="4Fe-4S single cluster domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1390_0106"
                     /evalue="6.00E-14"
                     /label="ctg1_1390"
                     /locus_tag="ctg1_1390"
                     /protein_end="219"
                     /protein_start="97"
                     /score="52.8"
                     /tool="antismash"
                     /translation="CLHIAHDCNLRCEYCFASTGDFGKGRKLMPLEIGKKAIDFLLEQS
                     RDRETLELDFFGGEPLMNFDVVKEVVKYARSKEQEYGKRFRFTITTNGMLLTDDKIDFI
                     NKEMSNVVLSLDGRREVN"
     CDS             11473..11865
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1391"
                     /sec_met_domain="TIGR04085 (E-value: 5.5e-22, bitscore:
                     75.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 5.4e-08, bitscore: 30.4,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDLDQGPCAIKRLRGCGCGNEYVAITPDGDIYPCHQFVGMEEYK
                     MGNLDEGTFNLDIKAEFAAAHVYTKPECKQCWAKFYCSGGCNANNYQYAGDIHNAHKFS
                     CQLQKKRLECAIMIKAAHLAEDLADK"
     PFAM_domain     11521..11703
                     /aSDomain="SPASM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13186.8"
                     /description="Iron-sulfur cluster-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1391_0107"
                     /evalue="4.40E-07"
                     /label="ctg1_1391"
                     /locus_tag="ctg1_1391"
                     /protein_end="77"
                     /protein_start="16"
                     /score="30.4"
                     /tool="antismash"
                     /translation="CGCGNEYVAITPDGDIYPCHQFVGMEEYKMGNLDEGTFNLDIKAE
                     FAAAHVYTKPECKQCW"
     aSDomain        11521..11787
                     /aSDomain="TIGR04085"
                     /aSTool="tigrfam"
                     /description="rSAM_more_4Fe4S: radical SAM additional
                     4Fe4S-binding SPASM domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1391_0030"
                     /evalue="1.10E-21"
                     /identifier="TIGR04085"
                     /label="ctg1_1391"
                     /locus_tag="ctg1_1391"
                     /protein_end="105"
                     /protein_start="16"
                     /score="75.1"
                     /tool="antismash"
                     /translation="CGCGNEYVAITPDGDIYPCHQFVGMEEYKMGNLDEGTFNLDIKAE
                     FAAAHVYTKPECKQCWAKFYCSGGCNANNYQYAGDIHNAHKFSC"
     CDS             complement(11966..12274)
                     /locus_tag="ctg1_1392"
                     /transl_table=11
                     /translation="MHTASEKSFYEIKEINQNGITFTNGEKIVFQACIKQGSNGKTCIA
                     ERDLFAQPPYFLFFTADRPTKILFNKKGIFSKSENRKHFRELQRMIIEFGYSSYDLG"
     CDS             complement(12370..13401)
                     /locus_tag="ctg1_1393"
                     /transl_table=11
                     /translation="MAVKVAINGFGRIGRLAFRQMFGAEGYEIVAINDLTDPKMLAQLL
                     KYDTAQGGYCGRIGQGLHTVEAGEGCIIVDGKKITIYAEPKAAELPWGKIGVDVVLECT
                     GFYCSKEKSQAHIDAGAKKVVISAPAGNDLKTIVFSVNENTLTKDDTIISAASCTTNCL
                     APMAKALNDYAPIQSGIMSTIHAYTGDQMILDGPHRKGDLRRARAGAANIVPNSTGAAK
                     AIGLVIPELNGKLIGSAQRVPVPTGSTTILTAVVKGKDVTKEAINAAMKAAASESFGYN
                     EDQIVSSDVIGMRYGSLFDATQTMVAQIAEDLYEVQVVSWYDNENSYTSQMVRTIKYFA
                     ELG"
     aSDomain        complement(12400..13392)
                     /aSDomain="TIGR01534"
                     /aSTool="tigrfam"
                     /description="GAPDH-I: glyceraldehyde-3-phosphate
                     dehydrogenase, type I"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1393_0031"
                     /evalue="8.60E-122"
                     /identifier="TIGR01534"
                     /label="ctg1_1393"
                     /locus_tag="ctg1_1393"
                     /protein_end="334"
                     /protein_start="3"
                     /score="404.4"
                     /tool="antismash"
                     /translation="KVAINGFGRIGRLAFRQMFGAEGYEIVAINDLTDPKMLAQLLKYD
                     TAQGGYCGRIGQGLHTVEAGEGCIIVDGKKITIYAEPKAAELPWGKIGVDVVLECTGFY
                     CSKEKSQAHIDAGAKKVVISAPAGNDLKTIVFSVNENTLTKDDTIISAASCTTNCLAPM
                     AKALNDYAPIQSGIMSTIHAYTGDQMILDGPHRKGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLIGSAQRVPVPTGSTTILTAVVKGKDVTKEAINAAMKAAASESFGYNEDQ
                     IVSSDVIGMRYGSLFDATQTMVAQIAEDLYEVQVVSWYDNENSYTSQMVR"
     PFAM_domain     complement(12436..12915)
                     /aSDomain="Gp_dh_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02800.22"
                     /description="Glyceraldehyde 3-phosphate dehydrogenase,
                     C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1393_0109"
                     /evalue="2.50E-51"
                     /label="ctg1_1393"
                     /locus_tag="ctg1_1393"
                     /protein_end="322"
                     /protein_start="162"
                     /score="173.5"
                     /tool="antismash"
                     /translation="LAPMAKALNDYAPIQSGIMSTIHAYTGDQMILDGPHRKGDLRRAR
                     AGAANIVPNSTGAAKAIGLVIPELNGKLIGSAQRVPVPTGSTTILTAVVKGKDVTKEAI
                     NAAMKAAASESFGYNEDQIVSSDVIGMRYGSLFDATQTMVAQIAEDLYEVQVVSWY"
     PFAM_domain     complement(13075..13395)
                     /aSDomain="Gp_dh_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00044.26"
                     /description="Glyceraldehyde 3-phosphate dehydrogenase, NAD
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1393_0108"
                     /evalue="3.40E-31"
                     /label="ctg1_1393"
                     /locus_tag="ctg1_1393"
                     /protein_end="109"
                     /protein_start="2"
                     /score="107.7"
                     /tool="antismash"
                     /translation="VKVAINGFGRIGRLAFRQMFGAEGYEIVAINDLTDPKMLAQLLKY
                     DTAQGGYCGRIGQGLHTVEAGEGCIIVDGKKITIYAEPKAAELPWGKIGVDVVLECTGF
                     YCS"
     CDS             13643..14728
                     /locus_tag="ctg1_1394"
                     /transl_table=11
                     /translation="MQTEQQRTQLAVLQDIFKHSHQYVWIADLSCQVLWCSHDSLPGAF
                     RDLDIGKLLRSHRGMRLCSGRYTCTLDGLTYSYSLLRYPDPEDQAKDLLVIQMAGEDVF
                     AAFLHDSMIREFLENQSGTIRQAVSGITAVSGQLAQRLRINQDEPARELLNVGISNCFR
                     LLRSTAHTTELLRYAEAPVQRVRIDVCAFLQEFAQACTELLQGHMQVTLEDTEPVYIVS
                     DPERFSACIQSMLLLSCGSGPCASLRIRAVCQREQLCISMLPAEADAPEKPAHRVRHDK
                     LEPLHPGNPLDSEAYLIRRYCSVFGGTLEQGEAGWQLRLPLASSEDAELLACCSPKLDY
                     AGNRFSRLQINLSQIAEFDFY"
     CDS             complement(14772..16379)
                     /locus_tag="ctg1_1395"
                     /transl_table=11
                     /translation="MPIKYVFVTGGVVSGLGKGITAASLGRLLKARGYKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFVDENLSVNSNVTTGKIYWNVLNKER
                     RGDYLGGTVQVIPHITNEIKEKIYRVGKATSTDVVITEIGGTVGDIESTPFLEAIRQFV
                     TEVGRENAMYIHVTLVPFIAGSNELKSKPTQHSVKELLSLGIQPNIIVCRTEMEIPEEM
                     AEKISLFCNVRREDIIQNTTAPSLYEVPLMLENEGLANAVCHHLHLDNPKPDLHEWIEM
                     VNRQKNAHKEVTIGLVGKYVALPDAYLSVAEALRHGGIVNDANVKILWINSEEITAETA
                     DGMLNMCDGIIVPGGFGDRGIEGMIEAIRYAREHQIPFFGICLGMQMAVVEFARNVAGL
                     TDANSSEFTPDGKNCVIDIMDDQKDITDKGGTMRLGLYPCKLAPDSLCAKLYGDPLIYE
                     RHRHRWEFNNSYRELLTQKGLSIAGLSPDERLVEIIELKNHPWFIGVQFHPEFKSRPNK
                     PQKLFADFIRASLANKEK"
     aSDomain        complement(14796..16373)
                     /aSDomain="TIGR00337"
                     /aSTool="tigrfam"
                     /description="PyrG: CTP synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1395_0032"
                     /evalue="6.40E-256"
                     /identifier="TIGR00337"
                     /label="ctg1_1395"
                     /locus_tag="ctg1_1395"
                     /protein_end="528"
                     /protein_start="2"
                     /score="847.9"
                     /tool="antismash"
                     /translation="IKYVFVTGGVVSGLGKGITAASLGRLLKARGYKVTIQKFDPYINV
                     DPGTMSPYQHGEVFVTDDGAETDLDLGHYERFVDENLSVNSNVTTGKIYWNVLNKERRG
                     DYLGGTVQVIPHITNEIKEKIYRVGKATSTDVVITEIGGTVGDIESTPFLEAIRQFVTE
                     VGRENAMYIHVTLVPFIAGSNELKSKPTQHSVKELLSLGIQPNIIVCRTEMEIPEEMAE
                     KISLFCNVRREDIIQNTTAPSLYEVPLMLENEGLANAVCHHLHLDNPKPDLHEWIEMVN
                     RQKNAHKEVTIGLVGKYVALPDAYLSVAEALRHGGIVNDANVKILWINSEEITAETADG
                     MLNMCDGIIVPGGFGDRGIEGMIEAIRYAREHQIPFFGICLGMQMAVVEFARNVAGLTD
                     ANSSEFTPDGKNCVIDIMDDQKDITDKGGTMRLGLYPCKLAPDSLCAKLYGDPLIYERH
                     RHRWEFNNSYRELLTQKGLSIAGLSPDERLVEIIELKNHPWFIGVQFHPEFKSRPNKPQ
                     KLFADFIRA"
     PFAM_domain     complement(14799..15473)
                     /aSDomain="GATase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00117.30"
                     /description="Glutamine amidotransferase class-I"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1395_0111"
                     /evalue="1.50E-58"
                     /label="ctg1_1395"
                     /locus_tag="ctg1_1395"
                     /protein_end="527"
                     /protein_start="302"
                     /score="197.8"
                     /tool="antismash"
                     /translation="LPDAYLSVAEALRHGGIVNDANVKILWINSEEITAETADGMLNMC
                     DGIIVPGGFGDRGIEGMIEAIRYAREHQIPFFGICLGMQMAVVEFARNVAGLTDANSSE
                     FTPDGKNCVIDIMDDQKDITDKGGTMRLGLYPCKLAPDSLCAKLYGDPLIYERHRHRWE
                     FNNSYRELLTQKGLSIAGLSPDERLVEIIELKNHPWFIGVQFHPEFKSRPNKPQKLFAD
                     FIR"
     PFAM_domain     complement(15576..16370)
                     /aSDomain="CTP_synth_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06418.16"
                     /description="CTP synthase N-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1395_0110"
                     /evalue="8.00E-129"
                     /label="ctg1_1395"
                     /locus_tag="ctg1_1395"
                     /protein_end="268"
                     /protein_start="3"
                     /score="428.7"
                     /tool="antismash"
                     /translation="KYVFVTGGVVSGLGKGITAASLGRLLKARGYKVTIQKFDPYINVD
                     PGTMSPYQHGEVFVTDDGAETDLDLGHYERFVDENLSVNSNVTTGKIYWNVLNKERRGD
                     YLGGTVQVIPHITNEIKEKIYRVGKATSTDVVITEIGGTVGDIESTPFLEAIRQFVTEV
                     GRENAMYIHVTLVPFIAGSNELKSKPTQHSVKELLSLGIQPNIIVCRTEMEIPEEMAEK
                     ISLFCNVRREDIIQNTTAPSLYEVPLMLENEGLANAVCHHLHL"
     CDS             complement(16532..16912)
                     /locus_tag="ctg1_1396"
                     /transl_table=11
                     /translation="MQGLEAIEGMELLYRTLPPDLQHWHCFGKILSLTYGTRFDESRLE
                     EIPVLSMLLTHQQGKYRIRLTLYNISGTVSFDVANGFFSGLTIDDFANCGYEADSRFRV
                     SSLEQNLAFTIYCARIRAELLS"
     CDS             complement(16890..18311)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 213.4; E-value: 1.3e-64)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1397"
                     /transl_table=11
                     /translation="MALHFWCYFMFFILVVFLLLWGFQIIFLEKFYDRMKTSDIQKVAA
                     HMLNIYGTENYEETYDELAYDNDLCIVVVDKYYRTVYSKDLMGNACLVHGFANYTSAFI
                     SQIRSSKTGTICGDIMNEHIRTNTLVYGTVIGTMDNPKGYLLLNTPLVPVGSTEAIIKR
                     QLLIISAILLMLGLLLSIYLSRRLARPIASLTKSAKQMAKGNYNVQFDGGSYLELQQLA
                     GALTYAAQEISRVDTLQRDLIANVSHDLRTPLTMMKAYAEMIRDLSGDNPVKRAEHLNI
                     IIEETDRLALMVNDILDLSKLESGGLALTPSTFGIRAKLSEIIDRYRGLSAKTGYHIHF
                     TPDEETMVTCDAGKIEQVICNLINNAVNYTGPNKQIFVRQINTPNGVRIEVQDTGAGID
                     KENLRMIFDKYYRSENHKREVVGTGLGLSIVKAIMKLHNYSYGVDSTLGKGSTFWFVIH
                     QDKKEETHHAGTGSH"
     PFAM_domain     complement(16932..17261)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1397_0114"
                     /evalue="9.90E-23"
                     /label="ctg1_1397"
                     /locus_tag="ctg1_1397"
                     /protein_end="460"
                     /protein_start="350"
                     /score="80.9"
                     /tool="antismash"
                     /translation="DAGKIEQVICNLINNAVNYTGPNKQIFVRQINTPNGVRIEVQDTG
                     AGIDKENLRMIFDKYYRSENHKREVVGTGLGLSIVKAIMKLHNYSYGVDSTLGKGSTFW
                     FVIHQD"
     PFAM_domain     complement(17397..17597)
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1397_0113"
                     /evalue="1.30E-18"
                     /label="ctg1_1397"
                     /locus_tag="ctg1_1397"
                     /protein_end="305"
                     /protein_start="238"
                     /score="66.8"
                     /tool="antismash"
                     /translation="QRDLIANVSHDLRTPLTMMKAYAEMIRDLSGDNPVKRAEHLNIII
                     EETDRLALMVNDILDLSKLESG"
     PFAM_domain     complement(17613..17765)
                     /aSDomain="HAMP"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00672.27"
                     /description="HAMP domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1397_0112"
                     /evalue="4.90E-06"
                     /label="ctg1_1397"
                     /locus_tag="ctg1_1397"
                     /protein_end="233"
                     /protein_start="182"
                     /score="26.9"
                     /tool="antismash"
                     /translation="LSRRLARPIASLTKSAKQMAKGNYNVQFDGGSYLELQQLAGALTY
                     AAQEIS"
     CDS             complement(18340..19014)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 211.6; E-value: 1.8e-64)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1398"
                     /transl_table=11
                     /translation="MKRLLIVDDEANIRLVVKEYAEFEGYEVAEAEDGMQAVELVKSQD
                     FDVIIMDIMMPRLDGFSACKEIKKYKNIPVIMLSARGEEYDKLFGFELGIDDYVVKPFS
                     PKELMARVKAVIKRSEHAAPANPDRLKFEGLEIDMAGREVYVNGKRVSMTPKEYDLLFY
                     LVKNSNIALTRDKLLEEVWGYDFFGDDRTVDTHIKMLRNSLGEYRKFIVTLRGMGYKFE
                     VR"
     PFAM_domain     complement(18352..18573)
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1398_0116"
                     /evalue="6.60E-24"
                     /label="ctg1_1398"
                     /locus_tag="ctg1_1398"
                     /protein_end="221"
                     /protein_start="147"
                     /score="83.9"
                     /tool="antismash"
                     /translation="GKRVSMTPKEYDLLFYLVKNSNIALTRDKLLEEVWGYDFFGDDRT
                     VDTHIKMLRNSLGEYRKFIVTLRGMGYKF"
     PFAM_domain     complement(18676..19002)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1398_0115"
                     /evalue="1.60E-31"
                     /label="ctg1_1398"
                     /locus_tag="ctg1_1398"
                     /protein_end="113"
                     /protein_start="4"
                     /score="108.9"
                     /tool="antismash"
                     /translation="LIVDDEANIRLVVKEYAEFEGYEVAEAEDGMQAVELVKSQDFDVI
                     IMDIMMPRLDGFSACKEIKKYKNIPVIMLSARGEEYDKLFGFELGIDDYVVKPFSPKEL
                     MARVK"
ORIGIN
        1 accaacatga tcctggaggg caagaaggtc acattctgct ctgaaaaata agagcagcaa
       61 ctgaatgccg ggcatcatcc tgcccggccc gtcaaagggg gagcgccctg gggcggtaag
      121 ctatgcgagg gagcctgtgg aacaggctga gagggtattg aagcgatgct tccattaccg
      181 accgtcaaag gggatccctc tgtgcatagc ttgggcttgt acagtggaat ccgaaaatct
      241 gtacaagaag gatgagaaac atgaaaacaa cacacaaaag caatctgatg aaactggtta
      301 tgctggcaat gctggtggcc atcggcgtgg tgatctcccc gattctccgg gtggagggca
      361 tgtgccccat ggcgcacttt atcaacattg tctgcgctgt gctgctgggt ccctggtatt
      421 ccctgctgtg cgccgtgctg atcggcatca tccgcatggc ctttatgggt attccgccgc
      481 tggcactgac cggtgcggtt ttcggtgcat tcctgtccgg catgttctac cggctgtcca
      541 aggggaagct gatcgccgcc tttctgggtg aggtgttcgg caccggcatc atcggggcta
      601 ttgtgtccta tccggtgatg acctatctgg tgggcagaac cgggctgacc tggtttttct
      661 atgtgccctc cttcatcagc ggcaccctga tcgggggcag tcttgccttt gtgttcctgc
      721 gggcgctggc gaaaaacgga cagcttgccc ggtttcagac cgctttgggc agtgtgtcct
      781 acgcagtctc ctccgatgtg tggagcaatg cggttggtat tgcggcactg gggctgatcg
      841 gctatctggc atcggtggtt ttgctgaaaa tgctgctgaa gctgtccggc acctgggtga
      901 ccgttgtgcc ctatgcgctg gtgggtgcgg cattgctggc ggctgtcatt tatctgatcc
      961 ggaatcggag tcagctgcgg cagcaggcat aagggaggct tttcatgaag aagcggattt
     1021 gcatgctgct ggagcagctc cggcagaagc agcctctggt acattgcatc accaacccca
     1081 tttccatcaa cgattgcgcc aatgctctgc tggcagttgg agcaagaccc atgatggcgg
     1141 agcatccccg ggaggtggcg ggtatcaccg cccatgccgg ggcgctgctg ctgaatctgg
     1201 gaaacattac ggatgtgcgg atggagtcca tgcagctggc agggcaggca gccatgcagg
     1261 caaaggtacc ggtgatcctg gatctggttg gggtggcatg ctccgatttg cggcgggaat
     1321 ttgccctgca tttgctggag cagatgcatc cggcggtgct tcggggaaac cgaaccgaga
     1381 tccgtgccat gcaggagcag attcatgcgg atggcgtgga cgtgtcccgg gaggatgcag
     1441 cagatacggg agcgtatctc aatgccgccc ggcaacttgc cgctcggtat gacacggtgg
     1501 tgctgaccag cggcgctgcg gatgatgtga ccgatggaca gaagcatgtg cgtgtgctgg
     1561 gaggcacgga gctgctttcc catgtgaccg gcaccggttg tatgcagggg gctttgatcg
     1621 ccgcttacct ggcggtgggt gcgcccctgg aggcggcagt gtgcggtgca gccgtgttgg
     1681 acgctgccgc ttcggcagtg ttgccgggtg tatccggtcc gggcagtctc cgcagcgccc
     1741 tggcggacgg actgtggaat ttgtcgccgg aacagctttg taagtattgt gaaatcgagg
     1801 aacagctatg aaatttgacc ccacattgta tttggtaacc gacagcagtt tgtatgagga
     1861 ggacgcattt ctttccgtca tagatggggt gtgcagcgcc ggtatcactc tgctgcagct
     1921 gcgggaaaag gaacgctcta cccgggaata cctccgactg gcacgggttg tccggcagat
     1981 tactgaccgg tacgggattc ctctgatcct ggatgatcgg gcagatgtgg ctgctgcatg
     2041 cggctgtgcc ggggtgcatg tcgggcagga ggatctgcct gtggaggatg cccggcggat
     2101 cctgggagcg gacaagatcg tgggagcaac ggcgaaaacc ctggaacagg cgaggatcgc
     2161 ctatgcccag ggggcggatt acctgggctg cggtgcagta tatcccacca ccaccaaggt
     2221 gcgcacggtg ttgactcctg tggaaaccat ccggcagatc tgcgaaagcg tgcccattcc
     2281 ggtgaatgcc atcgggggat tgaaccgggg gaacctggag atactgcggg gcgtgcccat
     2341 ccggggcgtt tgcgtggtgt ccgccatcat gaaggcagcg gatccggcac tggaaacccg
     2401 gctgctgaag gaagccgtcc ggacactgct ggaggatgca ccgtgcgctg cgcattgacc
     2461 attgccggtt cggattccgg cggcggcgct gggatccagg cggatctgaa aacctttgct
     2521 gcccatcatc tgtacggagc atctgtcatt accgcagtga ctgcccagaa tactctgggg
     2581 gtacgggaaa gctatccgct gcccccggag attgtggcgg cacagctttc cgccgtgctg
     2641 gaggatctgc atccggcagc catcaaaatc ggcatgctgg ggaatgggga catcgtccgg
     2701 actgtcagcc gggtgctggc tcagtatccg gatgtcccgg tggtgctgga tcccatcatg
     2761 ctgtccacct ccggacaccc cttactggat ccggagggag tatccgccat ggagcagctt
     2821 ttgtttccac gggcagctct gattaccccc aatctgccgg aggcacaggc attgaccggc
     2881 ttgcccttgt cggatttgca tgctgtaaag gcagcggcac agctgctgta ccgcacctat
     2941 ggctgcggcg tgctcatcaa gggggggcac agtgccggag agccggtgga tgtgctgtat
     3001 gatggcagtc tgcatgtttt caccgggaag cgtattcccg gcagggatgt gcacggcacc
     3061 ggctgtaccc tgtcctccgc cattgcggca gggcttgcac agggcatggc gctgccggag
     3121 gcggtacagg gggcgaagcg gtatctgtcc tgtgccatgg agagtgcctt ttccgttgga
     3181 tgtggcgctc ccgtgctgaa tcattttcta tcataaaaaa cgacccggag ggaatatccc
     3241 tccgggtcgt ttgctgtatc atacgcaagt tttgcacggt gacggatcag gttcccttca
     3301 cccgggcata agccacgatc acggaacgag gggcagccca gatgttggtg cagccctccc
     3361 aactgctctg ggtctggtaa atggggggat ccgcatgggg cagggcggtg ttgcaggcaa
     3421 tgtgccagta cagatgctcc ggcagatccg gcatctggat cttctggttt tcccaaaagg
     3481 tgttgatgcc caggaatacc atatcgtccg ctccggtttt cggatgcttg ccggaaaaga
     3541 gaatgccaat gacccgggta tccgggtgac agtctgtatg ccagggaaat gcattgtgaa
     3601 tgctgacggc ggggaagttg gtgcttgccg gttccagatt ttctgtaatg caggggtgtg
     3661 ccttccgcag agcgatcata tcccggcaga accggaagat ttcctgattt ttctccagca
     3721 gggaccagtc cagccaggat acttcgttgt cctgacagta gggattgttg ttgccgaact
     3781 gggtgttgca gaattcatct cccgcaagga acatggctgc accccggctg cacagcaggg
     3841 tggcaaaggc gttcttgata agccgcatgc gcagtgcccg gatttcctga ttgtccgtgt
     3901 ctccctcagc gccgcagttc cagctgtttc cacagttgtc cccgtccgta ttgttccagc
     3961 cgttggcttc gttgtgtttg gtgttgtagg cgtacagatc atacagggta aagccgtcgt
     4021 gacaggtgag aaaattgaca gaggcattgt ccccccggta taccgggtcg tacagatccg
     4081 tagagccggt gatccggttg atggctgcct gcgccatgtc cgcatctccc tttaagaagc
     4141 agcgcagatc gtcccggtat ctgccgttcc attccgccca gcggcgcaga gaggagaagc
     4201 tgcccacctg gtacagcccg ccggcatccc atgcttcggc gatcagcttt accttgctga
     4261 gtaccgggtc ataggcaaga ttccgcagca ggggcggatt ccgcatggga gagccgtcct
     4321 cgttcctgcc catgatggct gccaggtcaa accggaagcc gtcgatccgg tattccgttg
     4381 cccagtaccg gagacagttc aggatgaact gctgcaccac cgggtggttg cagttgaagg
     4441 tgttgccgca gccgctgaaa ttgaagtagc tgccgtccgg cgtgagcata tagtacacgt
     4501 tgttgtcgat gcccttgaag ctgaaggcgg agccctgttc attgccctct gctgtgtggt
     4561 tgaacaccac atccaggatc acttcaatgc cgtgttcatg cagcacacgg atcatctgct
     4621 tgagttcatt gccctcccgg ttgtattcgt tttcggagct gtagctggtg ttgggagaga
     4681 agaagctgac ggtgttgtag ccccagtaat tgtacagggt tttgccgtca atgactctgg
     4741 catcctccag ctcgttgaat tcaaacaccg gcatcagctc cactgcattg attccaagcg
     4801 ccagcagatg gggcagcttc tccagaatgc cggcaaaggt gcccggatgg gcaacgccgg
     4861 aagtgctgct ccgggtaaag ccgcggacat gcatttcata gatgatcaga tcccgcaggg
     4921 ggagctccgg actgcgcata tcgccccagt caaagctttc ggtaaccacc cgtgcgtgat
     4981 actggtgatc gtttgcggca ttttcgcccc attcatgctg accggtgacg gctcttgcgt
     5041 aaggatccag caggatccgt tccttgttga acagcagtcc cttccgggga tcgtgggggc
     5101 cgtccatccg gtaggcgtac tcaaattccg taatatccag cccgaacacg atgatggaga
     5161 acacatctcc gatccggtag gagtccggaa tggggatcac tgcatagggg gtcttttcct
     5221 tccggtgaaa cagcagaagc tcacaactgg tggcgttggc ggaggaaatg gtaaagttga
     5281 ctgcattggg cattgcggtt gccccctgga tcaggtgatt gcctggacgt accggaaaac
     5341 cgctgatggt atccacgggg atcaggggca tgtttgtaat gactgccatg tttatcttcc
     5401 ttctttgatt gatataccct tttattataa gcgaatcccg gaaaaaatgc aagcggcagg
     5461 gatatccgct tgcggctggg gaaaaagtgt gctataatgg tgtcgacaga aagcagggag
     5521 gtagcatatg aaaattcaga tattcggaaa ggcaaaaagc tttgacacca agaaggcgga
     5581 gcggtatttc aaggaacggg gcattccctt tcagtcggta gacattcttc ggaaggggct
     5641 gagccggggc gaactggaca gcgtgcttcg ggcagtgggc ggtctggagg cggtgattga
     5701 cgatacggca aaggactact gcatgatcaa atatctgctg gaggatgcaa agctagaaaa
     5761 gctgatggag cagcccagcc tgtaccgcac ccccatcgtc cgcaacggca gacaggctac
     5821 tgtgggctac tgtccggaga tatggaagca gtgggaagag gcggagcgtc atgcaatgtg
     5881 aaagctgtgt ctattatgta tatgatgagg agctggactg ctatagctgc ctggtagagc
     5941 tggacgagga cgaatacggc agattcctcc ggggagaatg ccgcagctgt ccctattacc
     6001 ggctggatga tgaatacggt gtggtcagac accagatgtg agggatcaga atgggaaaag
     6061 aagtaaagac aaatgcgatg cggatcctgg acagactgaa gctgccctat acgctgaaca
     6121 gctacgagtg caaggagttc attgacgggg tacacattgc ggatatgctg gggcaggatc
     6181 ctgcccagtc cttcaagacc ctggtgtgca gcggcaaggg gggcggctat tatgtattcg
     6241 tactgccggt tgcccgggaa ctggatctga aaaaagccgc ccgtgcagtg ggcgccaagg
     6301 cggtggaact gctgccggtg aaggagatca acgctgtcac cggatacatc cggggcggct
     6361 gtactgccat cggcatgaaa aagcagtatc ctacggtgat cgatcagtct gccggggaat
     6421 ttgaccggat catcatcagc ggcggacgca tcggcagcca gatttttctc gcaccggacg
     6481 attttatcaa agccaccgga ggcagttacg gggatattct tgcggaaatg taactccatt
     6541 ccgtttttgc atgatacggc actgggtttt ttcgaaaaat gcttgcaagg cgacagggaa
     6601 tatggtacaa tattatgatg cagggcggag ttacagcatc cctctgtgaa aaaacgggaa
     6661 aggagaaagg tctgcgtatt cacgcaggtc atacttaaaa tatgttccga attgttcaga
     6721 aaagagtact caatgatgcg gtagtactga tggaatttga agccccttac attgccaaga
     6781 aggcacaggc agggcagttt attattttcc gcatcgatga gcagggggag cggattccgc
     6841 tgaccattgc tgattacgac cgggagaacg gcaccatcac aatcattttt cagatcgtgg
     6901 gcaagtccac acagcatctt gccaccctca acgaagggga taccattctg gatctggtag
     6961 ggccgctggg agttcctacc cacctggatc cggatgtaaa gcgggtatgc gttgtggggg
     7021 gcggcgtagg ctgcgccatt gcatatcccc aggccaaggc gctccacagt aggggcatct
     7081 atgtggacgt aattgccggc ttccgcagca aggatattgt gatcctggag gatgagttca
     7141 aggctgtgtg caatgaactg gtgctctgca ccgatgacgg cagctacggc aagaagggct
     7201 ttgtgaccaa cgccctgcag gagctgatcg atgcaggcag aaattatgac gctgtcattg
     7261 ccatcggacc ggtgcctatg atgaagtttg tctgcaaggt aacagagcct tataatctga
     7321 agaccatcgt atccctgaac cccatcatga tcgacggcac aggcatgtgc ggcggatgtc
     7381 gggtaacagt ggggggcaag attcgctatg cctgcgtaga gggcccggat ttcgacggcc
     7441 accaggtgga ctttgacgag ctgatgcgcc gtaacggcac atacagagaa tacgagcagc
     7501 actgtcggct gatggcacag gctgaaaaat aatcggaaag gagcatatat ggacaggctc
     7561 tgcccatatt gatagaaagc tatggctaac atgtctttaa agaaggtgcc tatgccggag
     7621 caaaagccgg aagtgcgggc acggaacttt caggaagtaa ccctgggcta ttccaaggca
     7681 atggcaatgg aggaagcctc ccgctgtctg aactgtaaga acaagccctg cgtgtccgga
     7741 tgcccggtgg gagttcggat cccggagttt attgcatgtg ttgcagcagg ggattttgac
     7801 aaggcgtatg acatcatcac ctccaccaac ggtctgccgg cggtctgcgg tcgtgtatgt
     7861 ccccaggagc atcagtgcga gagcaagtgc gttcggggca tcaagggcga accggtgggc
     7921 attggtcgac tggagcgctt tgtagcggat tacaagatgg agcagggaaa taccaaggtt
     7981 gaggttcctg cctccaatgg acataaggta gcggtagtcg gcgcaggccc cagcggtctg
     8041 acctgtgcgg gggatctggc tcggctgggc tatcaggtta ccgtattcga ggcattccac
     8101 gttgccggcg gcgtgctgat gtatggcatt ccggagttcc gtctgcccaa ggccattgta
     8161 cagaaggaga tcaagactct gaaggcactg ggcgtgaaca ttatgaccga tatggtgatc
     8221 ggcaaggtgt tgtccgtgga tgagctgctg gaggatggct acgaggcgat tttcatcggc
     8281 tccggtgcag gtctgccccg gttcatgggc atcgagggcg aggcactggt aggcgtttgc
     8341 tccgccaacg agtatctgac ccggatcaat ctgatgaagg gctatctgga agagtatgat
     8401 actccggtca tcaagtccaa gcgggtcgca gtggtgggcg gcggcaacgt tgccatggac
     8461 gctgcaagaa gcgcaatgcg tatgggcgct gagcatgtat acatcgtgta ccgccgttcc
     8521 gaggaggaga tgcctgcccg gaaggaggag gtacatcacg ccaaggaaga gggcattgag
     8581 tttttgaatc tgaacaatcc ggtgaagatc atcggagacg aaaacggcag agtctgcgcc
     8641 atggagtgca tccgcatgga gctgggcgag ccggatgaaa gcggacgtcg cagccccatc
     8701 ccggtggagg gctccaacta caatttggag gtggatacgg taatcatgtc catcggcacc
     8761 tctccgaatc ctctgatccg gactaccact tccggtctgg aggcaaacaa gcggggctgt
     8821 ctgatcgtgg acgaggctat gtgtaccacc aaggaaggtg tgtatgccgg cggtgacgca
     8881 gtgaccggtg cagcaacggt aatcctggcc atgggtgccg gcaagactgc tgcccagtcc
     8941 atcgacaagt acattcagaa caagtaaaat caacgaggag gaacagtatg tttacgagtt
     9001 tgcacacatt cgcagctgaa cagagtgcca ccagcggtgg tgcgtatggc ttggtgggga
     9061 tcctgccctg ggtgatcgtt ctggttgcgc tgtacttcat tatgattcgt ccgcagcgca
     9121 agaaggaaaa agagactatc cggatgcgct ccaatatcca gatcggtgac gagattctga
     9181 ccatcggcgg cattgtaggc atcgttgtgc gcaagggcga ggatactgta gtcattgaaa
     9241 ccggcggcga ccgcagcaag ctgcggatcc ggatcgaggc tgtgcaggaa aatctgactg
     9301 cacaggagga agcggctaag gagaagaagg aaaagcagaa tgccaagctg acccccggcg
     9361 caccgaaaaa ggaaaagccc aagaaggaaa agagcgaatc cgaggaataa gcccttgcat
     9421 ccatgcatat gctcaaacag cataggacat ggagggcatg ggtatgagcc gacgaacacg
     9481 cagagcagct ccgtggtatc gcaagtattg gcttgcgatt gccggggggc tgcttctttg
     9541 tataggcatt ctcagcttgg gggcattggc tgcatctctg gcggatctgc cccggtgggt
     9601 gatgaacagc ctggtgctgg cagcgctggg ctgcggcgca tatctgaccg gcttactggc
     9661 agggcggcgc caccgtcggc atgggctgcg gaacggggga ctgctggggg tgctgttggg
     9721 aatctgcgtg cttgggatca gtacagcctg tacaggacat gtaccgcatc tgcacgcttt
     9781 ggtgcggctg gtgtggatgg cggtctgcgg cggcgcaggg ggcgtacaag gcgtcaatca
     9841 gaagcagcca ggggtgccgg aggagtagat ttcatacttt ctgtatatct gagtcgagat
     9901 tctacatatt tttattattt aatgattaga aaagggttga aatgtcgcgg atcctgtgat
     9961 ataatagatg taaattctga tgagattggt ggaggttagt atgaaacaca ttcagacaat
    10021 caataaggca aacctgaagg aaactgcaaa gaagggcggc tgtggcaagt gccaggcatc
    10081 ctgtcagtct gcttgtaaga cttcttgcac agttgcaaat cagaagtgtg agaaataatt
    10141 gattcaaaaa atgagcgtga tgaaaagggg cagcagtgtc ccttttcatt ttatcagcag
    10201 atttatgccg ctgccatgcg gcggaacggg gtaactggat atgatacaca agtttaaact
    10261 aaacggattc aatattgtgc tggacgtgaa cagcggcggt gtccatgtgg tggacgagct
    10321 gacctacgat ctgctggaca atgtgcagcc gccctttgca ccggaatgtc cccaggaggt
    10381 tgtcagcaag ctgacccggt tctatgcgcc ggaggatatc cgttcctgct atgaggagat
    10441 cctggagctg tacaaggaca agattctctt ttcggaggat gattacgaga aatttgccaa
    10501 gtattccgtt gcagcaccgg tcaaggccat gtgtctgcat attgctcatg actgcaacct
    10561 gagatgtgaa tactgctttg catccaccgg tgatttcggc aagggtcgga agctgatgcc
    10621 cttggagatc ggcaaaaaag ccattgattt tcttctggag cagtccaggg atcgggagac
    10681 tctggagctg gacttctttg gcggtgagcc tttgatgaac tttgatgtgg tcaaggaagt
    10741 ggtgaaatac gctcgcagca aggagcagga atacggcaag cggttccgct ttaccattac
    10801 caccaacggc atgctgctga cggatgataa gatcgacttc atcaacaagg aaatgtccaa
    10861 cgtggtgctg tccctggacg gtagacggga ggtcaacgac cgggtgcgca agcgtgtgga
    10921 cggtaccggc tgctacgacc ggatcctgcc tgcgttccag aagctggtgg cacagcgtgg
    10981 ggataaggat tactatgtgc ggggcacctt taccaagtac aatctggatt tctccgatga
    11041 tgtgttcagc ctgtatgatg caggctttga ccagatttcc gtggagccgg tggtcagtga
    11101 tcctgcaaag ccctatgctc tgaccgaacg ggagctgtct gatattttct gcgaatnnnn
    11161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnaaa gcggttcaac
    11461 ttcttccact ttatgatcga cctggatcag ggcccctgcg ccatcaagcg gctgcggggt
    11521 tgcggctgcg gcaatgagta tgttgccatc acgccggacg gagatattta cccgtgtcat
    11581 cagtttgtag gcatggaaga atacaagatg gggaacctgg atgagggaac ctttaatctg
    11641 gatatcaagg cggagtttgc tgcggcgcat gtatacacca aaccggaatg taagcagtgc
    11701 tgggcaaaat tttattgcag cggcggatgt aacgccaaca actaccagta tgcgggggat
    11761 atccacaatg cccacaagtt ctcctgtcag cttcagaaaa agcggctgga gtgtgccatt
    11821 atgatcaaag cggcgcacct tgcggaggat cttgcagaca aataaaacgt gtcggcgcag
    11881 attagaagta tttagcccgg aagtggtttg attgaactgc ttccgggctt atttgcatat
    11941 gacatttggg cataaatggg atgcatcaac ctaaatcgta cgatgaatag ccaaattcga
    12001 ttatcatcct ttgcagttct cgaaaatgct tccggttttc agattttgag aatatgcctt
    12061 ttttgttgaa aagaattttg gtgggtctat cagcagtaaa aaacagaaaa taaggaggtt
    12121 gggcaaatag atccctttct gcgatacaag ttttaccgtt gctgccttgt ttgatgcacg
    12181 cctgaaaaac gattttttcg ccgtttgtaa aagtaatccc attctgattg atctctttga
    12241 tctcataaaa actcttttca gatgctgtat gcatttttcc ctccttgttg agcgatgtat
    12301 tatgtttcat ccatataaaa agaaaacgcc gtttcccgaa agaaacggcg ttttgcaatc
    12361 gtaaaacgat tagcccagct ctgcgaagta cttgatcgta cgaaccatct ggctggtgta
    12421 ggagttctcg ttgtcatacc aggaaacaac ctgaacctcg tacagatcct cagcgatctg
    12481 tgcaaccatg gtctgggtag catcgaacag agaaccgtat ctcatgccga ttacgtcgga
    12541 agaaacgatc tgatcctcgt tgtagccgaa ggactcagaa gcagcagcct tcatagcagc
    12601 gttgattgct tccttggtta cgtccttgcc cttaacaact gcggtcagga tggtggtaga
    12661 accagtcgga accggaactc tctgtgcgga accgatcagc ttgccgttca gctccggaat
    12721 taccaggccg attgccttag cagcaccggt ggagttcgga acgatgtttg cagcacctgc
    12781 tcttgctctt ctcaggtcgc cctttctgtg cggaccatcc aggatcatct ggtcgccggt
    12841 gtaagcgtgg atggtgctca tgataccgct ctggatggga gcgtagtcgt tcagagcctt
    12901 tgccatggga gccaggcagt tggtggtgca ggatgcagcg gagatgatgg tgtcatcctt
    12961 ggtcagagtg ttctcgttta cggagaatac gatggttttc agatcgttgc cggcgggagc
    13021 ggaaataaca accttctttg cgcctgcatc gatgtgagcc tgggacttct ccttggagca
    13081 gtagaagccg gtgcactcga gtacaacgtc aacaccgatc ttgccccagg gcagctcagc
    13141 tgccttcggc tcagcgtaga ttgtgatctt cttgccatca acgatgatgc agccttcgcc
    13201 tgcctctaca gtgtggagac cctggccgat tctgccgcag taaccgccct gagcggtgtc
    13261 atacttgaga agctgtgcca gcatcttggg gtctgtcaga tcgttgattg ctacgatctc
    13321 atagccctca gcgccgaaca tctgtctgaa agccagacgg ccgatacggc caaaaccatt
    13381 gattgctact ttaactgcca ttggaatgta cctcctaata ttttatggtt ctattataca
    13441 ccatccgggc gcatttttca agtgctttgt caggaaaata actattattt ttcggtgcat
    13501 ttgcattctg caaggaaatc cattgtttca agtgtgcttt ttgtgcaaaa gcgacaattg
    13561 cggagaatct gaaaaaagtg gtgtacaaat gggagaaaat attgtataat acatacatgt
    13621 acaataacat ggaggggtca tgatgcagac agaacaacaa aggacgcagc tggctgtgct
    13681 gcaggatatt ttcaaacact cccatcaata tgtgtggatc gcagacctgt cctgccaggt
    13741 gctgtggtgc agccatgaca gtctgccggg ggcgttccgg gatctggaca ttggaaagct
    13801 gctccgatct catcggggca tgcggctgtg cagcggcaga tatacctgta ccctggatgg
    13861 actgacgtat tcctacagcc tgctgcggta tccggatccg gaggatcagg caaaggatct
    13921 gctggtgatc cagatggcag gagaggatgt atttgcggca ttcctccatg acagcatgat
    13981 ccgggaattt ttagaaaatc agtccggcac cattcgccag gcggtatccg ggattaccgc
    14041 agtcagcgga cagcttgccc agcggctccg catcaatcag gatgaaccgg ctcgggagtt
    14101 gttgaatgtg ggcatcagca actgcttccg cctgctgcgg agtacggcgc ataccacgga
    14161 gctgctccgg tatgcggaag cgcctgtgca gcgtgtccgc attgacgtgt gcgctttttt
    14221 gcaggaattt gcccaggcat gtacggagct gctacaggga catatgcagg tgactctgga
    14281 ggacacagag ccggtataca ttgtatcgga tccggagcgt ttttctgcct gcatccagtc
    14341 catgctgctg ctgagctgtg gctcgggtcc atgtgcctcc ctgcgcatcc gtgcagtgtg
    14401 tcagcgggag cagctttgta tttccatgct gccggcagaa gcggatgcac cggaaaagcc
    14461 ggcacaccgg gtgcggcatg acaagctgga accgctgcat ccgggaaatc ccctggattc
    14521 agaggcgtat ctgatccgtc ggtattgcag cgtgttcggt ggcacactgg agcaagggga
    14581 ggcgggctgg cagctacggc tgcccctggc aagctcggag gatgcggaac tgctggcttg
    14641 ctgctctccc aagctggatt atgcaggaaa ccggttctcc cggcttcaga tcaatctgtc
    14701 ccagattgca gaatttgatt tttattaagc aacgaaaagc ggtatcaccc cattggatga
    14761 taccgctgct tttatttttc cttgtttgcc agggatgccc gaatgaagtc tgcgaacagc
    14821 ttctggggct tgttgggacg ggacttgaat tccgggtgga actgtacgcc gatgaaccag
    14881 ggatggtttt tcagctcgat gatctccacc agccgctcgt ccggagagag ccctgcgatg
    14941 gacaatccct tctgggtgag cagctcccgg tagctgttgt tgaattccca acggtgccga
    15001 tgccgctcgt aaatcagcgg atccccgtaa agctttgcgc acagggaatc cggtgccagc
    15061 ttgcaggggt acagacccag tcgcatggta ccgcccttgt cggtgatatc cttctggtcg
    15121 tccataatgt cgatgacgca gttcttgccg tccggtgtga attcggagga atttgcatcg
    15181 gtcagaccag ccacattgcg tgcgaattct accaccgcca tctgcatgcc caggcagatg
    15241 ccaaagaagg ggatctgatg ctcccgtgca tagcggatcg cttcgatcat gccctcaatg
    15301 ccccggtcgc caaagccgcc gggtacgatg atgccgtcac acatgttcag catgccgtcg
    15361 gcggtttccg ctgtgatctc ttcagaattg atccagagga tcttcacgtt tgcatcattg
    15421 acgatgcccc cgtgccgcag tgcctctgca acggacagat atgcatccgg cagggcaacg
    15481 tacttgccca ccagaccgat ggtcacttcc ttgtgggcat tcttctgccg gttcaccatt
    15541 tcgatccact cgtgcagatc cggcttgggg ttgtccagat gcagatggtg gcacacagca
    15601 tttgcaagtc cctcattttc cagcatcaaa ggcacttcat acagggaagg cgcagtggta
    15661 ttctggatga tatcctcccg gcgcacatta cagaacaggc tgattttttc agccatctcc
    15721 tccgggatct ccatttccgt gcggcatacg atgatgttag gctggatacc cagggagagc
    15781 agttccttga cggaatgctg ggtgggcttg gatttcagct cattggagcc tgcaatgaag
    15841 ggtaccaggg ttacatggat gtacatggcg ttttctctgc ctacttcggt gacgaactga
    15901 cggatcgcct ccaggaaggg ggtactttcg atatcgccca ctgtgccgcc gatttccgtg
    15961 atgaccacgt cagtagaggt ggctttgccc accctgtaga tcttttcctt gatctcgttg
    16021 gtgatgtggg ggatgacctg cactgtgccg cccaggtaat cgccccggcg ctccttgttc
    16081 agtacattcc agtagatctt gccggtggtc acgttggagt ttacgctcag gttttcatct
    16141 acaaagcgct cgtagtgccc cagatccagg tctgtttccg caccgtcatc ggtgacgaat
    16201 acctcgccgt gctgataggg gctcatggta cccggatcca cgttgatata cgggtcaaat
    16261 ttctgaatgg tgaccttata gcctctggcc ttgagcaaac gtcccaggga agcggcagtg
    16321 atgccctttc caagtccgga aaccacaccg ccggtgacga atacgtactt aatcggcatt
    16381 ttcttatttc ctccagtcct aatctctgta tgaaatcata tcatttctat tttaccctgt
    16441 ttgcgtataa aaagcaagag gaaaaaagaa ttttgtcact ttattttggc ggatgcagaa
    16501 aaaacgccgt cccatggggg acggcgctgt cttacgaaag gagttctgcc cggatccggg
    16561 cacagtagat tgtaaaggca agattctgtt ccagggagga tacccgaaac cggctgtctg
    16621 cttcatagcc gcaattggca aaatcgtcaa tggtgagtcc gctgaagaag ccgtttgcga
    16681 catcaaagct gacggtaccg gaaatgttgt acaaggtcag ccggatccgg tattttccct
    16741 gttgatgggt cagaagcatg gaaagcaccg gaatttcctc cagtcggctc tcgtcaaagc
    16801 gggtaccgta tgtgagagaa aggattttgc caaagcagtg ccagtgttgt aagtccgggg
    16861 gcagcgtccg gtacagaagc tccatgccct caatggcttc cagtccctgc atgatgcgtt
    16921 tcctcctttt tatcctggtg gatcacaaac cagaaggtgg agcccttccc aagggtgctg
    16981 tccacgccgt aggagtaatt gtgcagcttc ataatggctt tcacgatgga cagtcccaag
    17041 ccggtaccca caacctcccg cttgtggttt tcgctgcggt agtacttgtc aaagatcatt
    17101 cgcagattct ccttgtcaat gcctgcaccg gtgtcctgca cctcgatgcg gacgccgttg
    17161 ggagtgttga tctgccggac aaagatctgc ttgttcgggc ctgtgtaatt gacggcgttg
    17221 ttgatcaggt tgcagatcac ctgctcgatt tttcctgcat cgcaggtgac catggtttct
    17281 tcgtccggcg taaagtggat gtggtagccg gttttggcgg acagcccccg ataccggtcg
    17341 atgatttccg acagctttgc ccggatgccg aaggtggagg gggtcagcgc cagtccgccg
    17401 ctttccagct tggacagatc cagaatgtca ttgaccatca gtgccagccg atcggtttct
    17461 tcaatgatga tattcagatg ctccgcacgc tttaccggat tgtctccgct cagatcccgg
    17521 atcatttccg catatgcctt catcatggtc agcggcgtgc gcagatcgtg ggacacgttg
    17581 gcgatcagat cccgctggag ggtatccact ctggagattt cctgtgccgc ataggtcagc
    17641 gcccctgcca gctgctgcag ctccaggtag ctgcccccgt caaattgcac gttgtagttg
    17701 ccctttgcca tttgcttggc ggatttggtc aggcttgcaa tgggtcgtgc cagccggcgg
    17761 gacagataaa tggacagcag cagacccagc atcagcagaa tggcagagat gatcagcagc
    17821 tgccgcttga tgatggcttc cgtggagcct accggcacca gtggcgtatt cagcagcaga
    17881 tagcccttgg gattgtccat ggtgccgatc accgtaccgt acaccagagt attggtgcgg
    17941 atgtgttcgt tcatgatatc tccgcagatg gtgccggtct tgctggagcg gatctgtgag
    18001 ataaaggcac tggtgtagtt ggcaaagccg tgcaccaggc aggcgttgcc catcagatcc
    18061 ttggaatata ccgtccggta gtacttgtcc accaccacga tgcacagatc gttgtcatag
    18121 gcaagttcat cgtaggtttc ttcgtagttc tccgtgccgt aaatgttcaa catatgggcg
    18181 gcaaccttct ggatgtccga tgtcttcatc cggtcataga acttttccag aaagatgatc
    18241 tggaatcccc acagcaggag aaataccacc aggatgaaga acataaaata acaccagaag
    18301 tgcagtgcca tgctttcgcc gcctgtccgg cggtgccgtt cagcgaactt caaacttata
    18361 ccccattccc cggagggtta caatgaattt ccggtattct cccaggctgt tccggagcat
    18421 tttgatgtgg gtatccaccg tccggtcgtc tccgaaaaag tcatagcccc agacctcctc
    18481 cagcagcttg tcccgggtca gggcaatgtt gctgtttttt accaggtaga acagcaggtc
    18541 gtactccttg ggggtcatgg atacccgctt gccgtttaca tagacctctc tgccagccat
    18601 gtcgatttcc agtccctcga atttcagccg gtccgggttg gcgggtgccg catgctcgct
    18661 gcgcttgatg actgccttga cccgtgccat cagctccttg ggggagaagg gcttgaccac
    18721 atagtcatca atgcccagct caaagccgaa cagcttgtcg tattcctcac cccgggcaga
    18781 aagcatgatg accggaatgt ttttatactt tttgatctcc ttgcatgcgg aaaaaccgtc
    18841 cagacggggc atcataatat ccatgatgat tacatcaaag tcctggctct tgaccaattc
    18901 cactgcctgc ataccgtcct ctgcctctgc aacctcatag ccttcaaatt ctgcgtattc
    18961 cttgacgacc agccggatgt tggcctcgtc gtccacgatc agtaaccgtt tcataagctt
    19021 gtctgcgtgc cctgttgagc cgcactcctt tcttggtttg ctgcttgtat cataccatac
    19081 tgatgccagt atatcaagcc cttgtgaaaa aactgtgacg ggcaaaaaaa gattccggga
    19141 gaattcttga gcagtttgca caaacagcca ggatttgaag cggaatcatt gacatttgcg
    19201 tgcatttttg gtataatcaa tgtatatata aatggggcgt cctccgcatc ggaagcggag
    19261 agtcagggga atgcgcacag cgcagatccg gttaggacag gatagcattg aaaagaaaaa
    19321 gatggttgat ctgtgagggg gtttttaccc ttgccaccgg tatcgtcatt gcctatgcgg
    19381 ctatgaaccg gcaggatgca tttttaattt ttacttcata tgtactggtg gtggcagtgc
    19441 tcagcgtggc gctgaccgtg tactggcaga gcagctctgc ccgggcgatg gaagccaacc
    19501 gccgccgcat tgcctatttt attgacaata tcaacacgcc ggcattgctg tgggacaatg
    19561 ccctggagca tatccggatc aatgacagcc tgcgacaggt gctgggcttt gcagaggggg
    19621 agacccttac aaaagagcag ttcccggcac tgtttgagcg gcaggactgg aaggagcagg
    19681 acattcagga tattctccgg agccggaatg cagagtttgt gatccatacc cgcagcggtc
    19741 aggcggtcac catggtctgg agcacctccg gcatgcagca gacggaaaac acctgcctgt
    19801 tcatgaccat cggggtgaac gtgacggaga cccggcagat gcagtcggag atcgagatgt
    19861 tctccaatca gctggcagcc tctgaatggc ggtattccct gtccatggag ctgtcagaga
    19921 tcggcattct gctgacccag ggggacaagt atttcatttc tccggagctg cagcgcatgc
    19981 ttgggctgga tgaagcctct gtatccttcg ctgccttccg gcggatggtg catcccaatg
    20041 acacggtgat ctacgacacc tttatgcgca gtgtggagcg gctaccccag atgcaggagg
    20101 atccggagga tcagatccac tccatggagc tgcggcttcg ttcggcggac ggggaatatc
    20161 actggtacaa ctatcgctac aaggcggcaa agctggttgg ggcggatacc cccatcatcg
    20221 gcggctcctt catcaacatg gacacggaaa aggaaaagga cgctttgatc gagcggctgg
    20281 cttatgtgga cgaggtcacg ggcatttcca accggaacaa gctgatgctt atgggacagg
    20341 agacctatgt atgttccctg gagctgggga ttacctactt tgtcatggtg ctggacattg
    20401 accggttcca cctggtgaat gatgcctacg gctacgaatg cggcaacaag accttacagg
    20461 attttgccca cattatgtat aagtatctgt ccttcggggg ctttggtgcc cggatctctg
    20521 cggacaactt tgcgctgatc ctccgggatt acggggatga ggagctgccg gtcaagacca
    20581 tggaacggat ccaggcggat cttgcccagt tgggtatgac ggagctttcc gccaaggcgc
    20641 tgacctgctc cgccggctat tcccggatgc cccaggacgg tgaatccttt gcggaggtac
    20701 tggagcatgc ggaatttgcc ctgtcctctg cggagcaccg gaagggcacg gtggtaggct
    20761 acaacagtag tatgcatgat accattgtag gggagagcga gctggaaaag cagttgtccg
    20821 atgccattga caatggggaa ctgcggctgt actatcagcc caagatcgca ttgaccaacg
    20881 gcaggattat cggtgtggag gcattgatcc gctggatccg gccggacggc acggtggtgc
    20941 agccaggcag ctttgtgccc attgcggaaa cctcccagct gatccggaaa atcagcgatt
    21001 atgttctgtc cgaggcatgt gagcagaacc ggatctggca gcggatggga ctgcccaata
    21061 tcatcatgtc catcaacctg acttcggcgg atttctatca aaccaacgtg tgcgaggcag
    21121 tgtatgaagc tctggcacgg actggtctgg aggcacagtg gctggagatc gagctgacgg
    21181 aatccctggc tctgaaggat ctggatatgg cactggagca gatgcaccag ctgcgtgcca
    21241 tgggcgtgcg tctggcgatg gacgatttcg gtaccgggta ctcctcactg agctatttgc
    21301 aggtattgcc cattaccctg ttgaagctgg atcgcagctt tgtggtgaat ctggagcagg
    21361 atgagattgc aagagagatt gtggcagcgg tgatccgcat tgccaagtcc aagcatattg
    21421 aaaccattgc ggagggcatc gagcacccgg agcaggcaag gctgctgcgg atcgcc
//
