LOCUS       c00033_NZ_JAAX..       20736 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JAAXCM010000023.1 Coprococcus catus strain VPIC661
            NODE_3_length_258781_cov_149.876_ID_5, whole genome shotgun
            sequence.
ACCESSION   c00033_NZ_JAAX..
VERSION     c00033_NZ_JAAX..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:48:42
            Original ID  :: NZ_JAAXCM010000023.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 180482
            Orig. end    :: 201218
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..20736
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[190482:191218]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10736
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..20736
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..20736
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="3"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(1753..3690)
                     /locus_tag="ctg33_173"
                     /transl_table=11
                     /translation="LGWLLELLIEGIREICSQFLVDMMDLITGMFTDLLSCNLSLFEDL
                     FTVVKDLYKNAILPMGIAILLLILIWQLFKTMFGRGGVAAEDPVELVCRSFLCLFMLLF
                     ARPVANYILEVAGTPYQWVAGTEIEVKSFSDFVSSLDQASASLGIDGLSISILLLIMQF
                     VVAWNYFKMLFIIAERYVLLGVFSYTAPLAFSTGGSKATNNVLASWSKMFGGQVVLIIM
                     NAWCMKMFLSGYGNLTASHYGFTKFFIATLCLIGFSKVCFKMDSYMASLGINLGRMSNG
                     MGAFGLMMAASRLFSFGHSSHSTTESMENGEHTGNSEAMGTSSGMGDGAGPIPMSTGNP
                     MDMEEMGEDYVSGNPLEEGYADNADDGKTADTVSDQENILDEMGITSQQEEMKNPEAST
                     ENYGLGEGGELVKGEEIEPTQEQGNLSDLKENSVSEVPAMEAENTGSSYAEGMLDTDSI
                     PVESENGQEVLTEADGALDYPREEETATSVGMDLDGGTIGESEMDLEGVTSGSAGREYS
                     AQEVSGGMETSGSGILNEIGESGVSTSKGESVIPKFSEETREHPTGDCLSSQNEFGQGA
                     ERRISDVPTTGEMETSDVLGREMLIQGQNLRESVLPNEAERSLKLEDGIPEIPKSRREL
                     RQGYDERKDW"
     CDS             complement(3742..4143)
                     /locus_tag="ctg33_174"
                     /transl_table=11
                     /translation="LFHKKLQVHIVEKLRKPQFKMKTAWIPQFMFMGFFMITMLAWFTQ
                     PVYAADIFSMAKDAMQKVYNDVVGIATVAAVVCSAVCLFLMNFSKSGKTVDESRTWLKR
                     IVICWAVLMVLGAIVNYMEVLVPQQNFTG"
     CDS             4515..4961
                     /locus_tag="ctg33_175"
                     /transl_table=11
                     /translation="MKKKILTLLLTVTALGVIPFSVYASDTDTAKENECNEVITNQKII
                     NEKNPDGTITQAGLVTFEYQPSSSDLKAGGCSSGHHTNIVNNGTPDTTRIHGKTHPGYC
                     QVKTTTYWRCTNCNTTGHDDKYTLVWCPSADISGDEPGNEPGLQ"
     CDS             complement(5230..5760)
                     /locus_tag="ctg33_176"
                     /transl_table=11
                     /translation="MSWICFHIENERLLKAAVSEEIRVECDKLFRQRGYEERGRWIPEK
                     EVILSYIVEEVYYAAVRTTDRFGKSFVYAAVLPLCIQKGMYYNLLCNEQYEGELPQECQ
                     CPMEILLLLSSTDSVLAQKWRNNCWNYHKKEHYQEYKANVRKQSSGYRKKENYKRDFRR
                     KITTQSWYKAANV"
     CDS             complement(5836..6069)
                     /locus_tag="ctg33_177"
                     /transl_table=11
                     /translation="MVKSKKIKKMIWTHGWVVFPVITGRPLHYYWKGNKFQTEVVKKII
                     ALDVNHIVVEGEEKTYYIQFFADEAESLKAAA"
     CDS             complement(6262..6489)
                     /locus_tag="ctg33_178"
                     /transl_table=11
                     /translation="MQEREFEELLWKARNKDKKAVFEIIEMYRPLLLKYAKSNGKFDED
                     LYQELVCAVLKSIIKFPMKTEEHNNLYIKY"
     PFAM_domain     complement(6304..6468)
                     /aSDomain="HTH_16"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12645.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_178_0035"
                     /evalue="1.90E-13"
                     /label="ctg33_178"
                     /locus_tag="ctg33_178"
                     /protein_end="62"
                     /protein_start="7"
                     /score="50.4"
                     /tool="antismash"
                     /translation="ELLWKARNKDKKAVFEIIEMYRPLLLKYAKSNGKFDEDLYQELVC
                     AVLKSIIKFP"
     CDS             complement(6470..6913)
                     /locus_tag="ctg33_179"
                     /transl_table=11
                     /translation="MDKQKRTTIDEFSAYLQSAVRNTTINYMNDKSKIKEHEITLEEDL
                     ENVEGRGIEWNEMMEAHDIFWGKIDTEKLFAQVTDNKLLHILKSFSALHIKVLCLRILY
                     EKTFDEIGMAIGISGKKAENTYYNVIKKIRRELGEGKDAGKRI"
     CDS             complement(7098..7499)
                     /locus_tag="ctg33_180"
                     /transl_table=11
                     /translation="MRNRVEYILGGMTILQGLLVGMAWNGKKWAFLLLTLLLLLQEMVL
                     ILLLVRKRYQKKFCPKCGIEIIIWYRICPNCGHIFKPGCKKEDLTEMIEDALDQEEIGE
                     FDQLENSTDRMEEIEECMIERYIHNEKNI"
     CDS             complement(7513..7866)
                     /locus_tag="ctg33_181"
                     /transl_table=11
                     /translation="MAKQNPYRFSLGFDEEDPDHQEVARILNQLGHRKAKFVVKAVLAY
                     HQNIEGKFSKEQAVIDKKLDIPKKNRVVQLQDEFLPTLQEEDILMIQKNKELLQEMEKE
                     ELEENKSFYKEEL"
     CDS             complement(7878..8825)
                     /locus_tag="ctg33_182"
                     /transl_table=11
                     /translation="MGVVMSIDTGNKMMKTNHFIFHSGIKRKEQKILPGEEGIFFKGIN
                     YLESNQRISYLEDKTIDDRYYILTLLGVAKELEKEGIETGIYEGGTIPIQLLVGLPPGD
                     YGKQIRKFREYFWRQGKAVYFSYKGKPYRIRYESVNVYMQGYSAYILVANQLYLQEQPK
                     VLLIDIGGFTVDYLLVRYGVVDRTRIDSLPEGIIMLYKRIMVGIRQRFNLYLEEADIDN
                     ILFKRKTPYSELVVRRTFEIAAEYMGDLLGSFLEFGIDFRTTVTVFVGGGTVLLKDIID
                     EVWKRYHSTYYVVDDPRANVKGFIKQYMAEKAGY"
     PFAM_domain     complement(8388..8708)
                     /aSDomain="ALP_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17989.3"
                     /description="Actin like proteins N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_182_0036"
                     /evalue="1.40E-06"
                     /label="ctg33_182"
                     /locus_tag="ctg33_182"
                     /protein_end="146"
                     /protein_start="39"
                     /score="28.7"
                     /tool="antismash"
                     /translation="FFKGINYLESNQRISYLEDKTIDDRYYILTLLGVAKELEKEGIET
                     GIYEGGTIPIQLLVGLPPGDYGKQIRKFREYFWRQGKAVYFSYKGKPYRIRYESVNVYM
                     QGY"
     CDS             complement(8862..9416)
                     /locus_tag="ctg33_183"
                     /transl_table=11
                     /translation="MRKSGVVSKDVKGKDNEVYHDIISLFKIYRSVNWKMQIKINQVKQ
                     CFHTEYGTDVDEFLDSVYQAGMDINLDMEDMRERIESINQANKYLKLIDEAVELMRKYH
                     PQGEKYYWVLYYTYMSAYRAENTDEILDKLEPHFPRIPRMHRATYFRWRDKAFEAVSNI
                     LWGYETKNQQILKQVNQNYQE"
     CDS             complement(9423..9560)
                     /locus_tag="ctg33_184"
                     /transl_table=11
                     /translation="MIKIAVIILCIITISMIACILCTSVIAGKRADESIERYFKEQKRG
                     "
     CDS             complement(10001..10582)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_185"
                     /sec_met_domain="AgrB (E-value: 1.8e-31, bitscore: 102.8,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLSKLLTDYIVKKNTISETDYEIYKYGFLIGIELLTCMVICYI
                     LAIKMQMFWECTAFFLLFFSLRSLVGGLHMNSFKVCFLCSCLVVFFTLSMIKYFPISKE
                     FSLVISVFEIIILYYMKPVENINRPVNEKEKNVFSNRIRQTLIIITFSVCFFYLANILK
                     YLVTIVYTLGIIIISMILGKAKNQIERCRG"
     PFAM_domain     complement(10046..10567)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_185_0037"
                     /evalue="1.10E-29"
                     /label="ctg33_185"
                     /locus_tag="ctg33_185"
                     /protein_end="179"
                     /protein_start="5"
                     /score="103.2"
                     /tool="antismash"
                     /translation="KLLTDYIVKKNTISETDYEIYKYGFLIGIELLTCMVICYILAIKM
                     QMFWECTAFFLLFFSLRSLVGGLHMNSFKVCFLCSCLVVFFTLSMIKYFPISKEFSLVI
                     SVFEIIILYYMKPVENINRPVNEKEKNVFSNRIRQTLIIITFSVCFFYLANILKYLVTI
                     VYTLGIIIISM"
     CDS             complement(10584..10736)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg33_186"
                     /sec_met_domain="TIGR04223 (E-value: 2.6e-13, bitscore:
                     43.8, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKIKFFMKNHASVMASIAMVFSVMAINSRCVCIYHQPPMPDSLQ
                     KLKKN"
     aSDomain        complement(10599..10703)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg33_186_0004"
                     /evalue="4.70E-12"
                     /identifier="TIGR04223"
                     /label="ctg33_186"
                     /locus_tag="ctg33_186"
                     /protein_end="46"
                     /protein_start="11"
                     /score="43.8"
                     /tool="antismash"
                     /translation="ASVMASIAMVFSVMAINSRCVCIYHQPPMPDSLQK"
     CDS             complement(10954..12219)
                     /locus_tag="ctg33_187"
                     /transl_table=11
                     /translation="LLTLISIVILKIYFETFFEQDKRGIIGEFFWIFYFMWQFILGRTN
                     VLPAYINVMINVFLVSMLCINTYEGGILQKIVFSVLINTIWMLAEFLVGYMFVLCGIHY
                     MVPQFWGSLFSKLFTLFMIICLKKFFQNENVKDLSNKYNITLLLIPIGSMFVVYNTFML
                     SVDINKKVHIKESLTSLIIILLINIVIFKLYLVMSKEKELEKYNAVYEQQLELCTQHMR
                     EKENIMMDFRNARHDIKQHVIVLIEMLDNNQNESAIDYLRKLINIVPLNNLGISRTDNI
                     VVDSLINAKYAIALKEKIKFNVDIHIPMQLPFYSADLSILLGNILDNAIEASLQVTEDN
                     RYIKLFMKFEMNVLIITVVNAYNGKLVKNRNGKIVTSKAETGYHGIGLESVQKVATKYH
                     GSVVVETKQKVFTIKVILCDLS"
     PFAM_domain     complement(10969..11277)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_187_0038"
                     /evalue="7.10E-26"
                     /label="ctg33_187"
                     /locus_tag="ctg33_187"
                     /protein_end="417"
                     /protein_start="314"
                     /score="90.1"
                     /tool="antismash"
                     /translation="SADLSILLGNILDNAIEASLQVTEDNRYIKLFMKFEMNVLIITVV
                     NAYNGKLVKNRNGKIVTSKAETGYHGIGLESVQKVATKYHGSVVVETKQKVFTIKVIL"
     CDS             complement(12248..12973)
                     /locus_tag="ctg33_188"
                     /transl_table=11
                     /translation="MLEIAVCDDDILIAADIEKMLEKLSLIVAIKVEIDVFYDGSTLVD
                     YIKKGKRYDIIYLDIEMRKQNGVEAARIIRRIDKKVLIIYVTSHESFAKEVFEVSAFRF
                     ITKPIVPDVFQRYFLAAKNEILNHPQYFQYQYNKISYRIPIDEIMYFQSDRRVTYIITK
                     KGNRKCYGKLNDIEKRLNEANTYFYRTHQSFLVNPKFVAAYIYDSMELIDGTTLAISEN
                     RRKNVSELYCALKGEDIIV"
     PFAM_domain     complement(12287..12553)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_188_0040"
                     /evalue="4.10E-15"
                     /label="ctg33_188"
                     /locus_tag="ctg33_188"
                     /protein_end="229"
                     /protein_start="140"
                     /score="55.9"
                     /tool="antismash"
                     /translation="YRIPIDEIMYFQSDRRVTYIITKKGNRKCYGKLNDIEKRLNEANT
                     YFYRTHQSFLVNPKFVAAYIYDSMELIDGTTLAISENRRKNVSE"
     PFAM_domain     complement(12638..12964)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_188_0039"
                     /evalue="1.30E-16"
                     /label="ctg33_188"
                     /locus_tag="ctg33_188"
                     /protein_end="112"
                     /protein_start="3"
                     /score="60.8"
                     /tool="antismash"
                     /translation="IAVCDDDILIAADIEKMLEKLSLIVAIKVEIDVFYDGSTLVDYIK
                     KGKRYDIIYLDIEMRKQNGVEAARIIRRIDKKVLIIYVTSHESFAKEVFEVSAFRFITK
                     PIVPD"
     CDS             complement(13001..13378)
                     /locus_tag="ctg33_189"
                     /transl_table=11
                     /translation="MESKIKTSSNNSYLRKSQKPLYIDMGKRLRILRIELNYTQEQMAE
                     ILEMSSAYYGKIERGIHGLSLDKLVIVNKKLDIDINYLLTGVKRGDFSLDKVLMECPRT
                     KRYDIEQLIKHALNLVRDVDN"
     PFAM_domain     complement(13130..13294)
                     /aSDomain="HTH_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01381.24"
                     /description="Helix-turn-helix"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_189_0041"
                     /evalue="2.80E-10"
                     /label="ctg33_189"
                     /locus_tag="ctg33_189"
                     /protein_end="83"
                     /protein_start="28"
                     /score="40.2"
                     /tool="antismash"
                     /translation="LRILRIELNYTQEQMAEILEMSSAYYGKIERGIHGLSLDKLVIVN
                     KKLDIDINYL"
     CDS             13989..14315
                     /locus_tag="ctg33_190"
                     /transl_table=11
                     /translation="MRSKRIPAEEQYRLIMECRQSGLTDHQWCVEHDIKPGTFYNWVKR
                     LRQKSCMDLPASTGRSHSAPESQEVVRVDFHDTDTLSYEQPLNMIPASTKRNNISVAEP
                     MRLC"
     CDS             complement(14575..16218)
                     /NRPS_PKS="Domain: AMP-binding (40-456). E-value: 1.7e-72.
                     Score: 236.1. Matches aSDomain:
                     nrpspksdomains_ctg33_191_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     240.6; E-value: 4.4e-73)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg33_191"
                     /sec_met_domain="AMP-binding (E-value: 4.6e-75, bitscore:
                     246.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLDENVVENYINTVIIENKISEVSFKNLEKFHFAYDIIDKIAEI
                     NPKKIAILHIDENKIEKSINYKELKNCSNRMANFFAAQGIKKGDAVLIALRRAYQFWYI
                     FLGLIKIGAIPIPVVSQLREVDIKARINISNAKAIISLYGEDFQKETDKVINECVNTTI
                     LRFSIRGGNKNWINIDKENEKFSNDLVKPQDYNAMDIMFILFTSGTSGTPKMVVHDNLY
                     PLAHYITGKYWNNIEQDKLHLTISDTGWGKALWGKLFGPWLSGGCVFVYDFRKFEGSDI
                     LHMIEKYKINTICMPPTMYRMLLRSEIKKYDLSSITCACSAGEILPKDIINRFYLLTGI
                     KIANGYGQSETGLLIADFKKRKCNTGSIGYPNPIYKIELMKNTGEIITSEEIGEVGEIV
                     IDCRKKIPIGLASYLQVSEKKETSHIINGYYHTNDLAYRDAMGAYWYIGRNDTLIKSSG
                     YKINPYEIESVLANLNYIRECKVYGVVDEIRGNIIKADIVLSEEKVGTEELKKEIQDFV
                     KTTTAPYKYPRKIEFVSAIEKTMTGKIVRN"
     PFAM_domain     complement(14590..14826)
                     /aSDomain="AMP-binding_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13193.8"
                     /description="AMP-binding enzyme C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_191_0043"
                     /evalue="1.40E-15"
                     /label="ctg33_191"
                     /locus_tag="ctg33_191"
                     /protein_end="543"
                     /protein_start="464"
                     /score="58.1"
                     /tool="antismash"
                     /translation="EIESVLANLNYIRECKVYGVVDEIRGNIIKADIVLSEEKVGTEEL
                     KKEIQDFVKTTTAPYKYPRKIEFVSAIEKTMTGK"
     CDS_motif       complement(14818..14883)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg33_191_0002"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg33_191"
                     /protein_end="467"
                     /protein_start="445"
                     /score="18.0"
                     /tool="antismash"
                     /translation="YIGRNDTLIKSSGYKINPYEIE"
     PFAM_domain     complement(14851..16095)
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_191_0042"
                     /evalue="6.90E-63"
                     /label="ctg33_191"
                     /locus_tag="ctg33_191"
                     /protein_end="456"
                     /protein_start="41"
                     /score="212.8"
                     /tool="antismash"
                     /translation="IAEINPKKIAILHIDENKIEKSINYKELKNCSNRMANFFAAQGIK
                     KGDAVLIALRRAYQFWYIFLGLIKIGAIPIPVVSQLREVDIKARINISNAKAIISLYGE
                     DFQKETDKVINECVNTTILRFSIRGGNKNWINIDKENEKFSNDLVKPQDYNAMDIMFIL
                     FTSGTSGTPKMVVHDNLYPLAHYITGKYWNNIEQDKLHLTISDTGWGKALWGKLFGPWL
                     SGGCVFVYDFRKFEGSDILHMIEKYKINTICMPPTMYRMLLRSEIKKYDLSSITCACSA
                     GEILPKDIINRFYLLTGIKIANGYGQSETGLLIADFKKRKCNTGSIGYPNPIYKIELMK
                     NTGEIITSEEIGEVGEIVIDCRKKIPIGLASYLQVSEKKETSHIINGYYHTNDLAYRDA
                     MGAYWYIGRNDTLIKS"
     aSDomain        complement(14851..16098)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg33_191_AMP-binding.1"
                     /evalue="1.70E-72"
                     /label="ctg33_191_AMP-binding.1"
                     /locus_tag="ctg33_191"
                     /protein_end="456"
                     /protein_start="40"
                     /score="236.1"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="KIAEINPKKIAILHIDENKIEKSINYKELKNCSNRMANFFAAQGI
                     KKGDAVLIALRRAYQFWYIFLGLIKIGAIPIPVVSQLREVDIKARINISNAKAIISLYG
                     EDFQKETDKVINECVNTTILRFSIRGGNKNWINIDKENEKFSNDLVKPQDYNAMDIMFI
                     LFTSGTSGTPKMVVHDNLYPLAHYITGKYWNNIEQDKLHLTISDTGWGKALWGKLFGPW
                     LSGGCVFVYDFRKFEGSDILHMIEKYKINTICMPPTMYRMLLRSEIKKYDLSSITCACS
                     AGEILPKDIINRFYLLTGIKIANGYGQSETGLLIADFKKRKCNTGSIGYPNPIYKIELM
                     KNTGEIITSEEIGEVGEIVIDCRKKIPIGLASYLQVSEKKETSHIINGYYHTNDLAYRD
                     AMGAYWYIGRNDTLIKS"
     CDS_motif       complement(15565..15615)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg33_191_0001"
                     /evalue="1.00E-05"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg33_191"
                     /protein_end="218"
                     /protein_start="201"
                     /score="18.2"
                     /tool="antismash"
                     /translation="FILFTSGTSGTPKMVVH"
     CDS             complement(17024..18232)
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 219.7; E-value: 1e-66)"
                     /gene_kind="transport"
                     /locus_tag="ctg33_192"
                     /transl_table=11
                     /translation="VIEKRIVNWKSRTVLFLISQCVTLFGSTLVQMAIVWYVTLNTSSG
                     VWVAAFSICSYLPQFLMSFIGGVWADRYSRKRLIIGADISIAAVTFIMMLAMPFIREEK
                     FLLGGLLVMSIIRSVGAGIQTPAVNAVIPQLVPESQLMRFNGINATMQSLVQFAAPAAA
                     GLLLSLSTLQSTLIIDILTAVFGVGILSCVLIPKQRSIEKSASVIKDMRMGIHFAFSDK
                     LIRKLLIVYGLFTFLCVPAGFLAGLLVNRVYGNTYWYLTAVELIGFFGMIMGGLLMSLW
                     RGFKSRINTLVFGLFIFGIMAVGMGLTKKFILYLILMALYGVALTIVQTSITTLIQENV
                     KSLMQGRIFGLMGSMYSGFIPIGMVIFGPMADIIPLEWIIVCSGVLVMMIAMILRFDHQ
                     LYK"
     PFAM_domain     complement(17051..18181)
                     /aSDomain="MFS_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF05977.15"
                     /description="Transmembrane secretion effector"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_192_0044"
                     /evalue="2.90E-22"
                     /label="ctg33_192"
                     /locus_tag="ctg33_192"
                     /protein_end="394"
                     /protein_start="17"
                     /score="78.9"
                     /tool="antismash"
                     /translation="ISQCVTLFGSTLVQMAIVWYVTLNTSSGVWVAAFSICSYLPQFLM
                     SFIGGVWADRYSRKRLIIGADISIAAVTFIMMLAMPFIREEKFLLGGLLVMSIIRSVGA
                     GIQTPAVNAVIPQLVPESQLMRFNGINATMQSLVQFAAPAAAGLLLSLSTLQSTLIIDI
                     LTAVFGVGILSCVLIPKQRSIEKSASVIKDMRMGIHFAFSDKLIRKLLIVYGLFTFLCV
                     PAGFLAGLLVNRVYGNTYWYLTAVELIGFFGMIMGGLLMSLWRGFKSRINTLVFGLFIF
                     GIMAVGMGLTKKFILYLILMALYGVALTIVQTSITTLIQENVKSLMQGRIFGLMGSMYS
                     GFIPIGMVIFGPMADIIPLEWIIVCSGVLVMMIAMIL"
     CDS             complement(18225..19079)
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 67.2; E-value: 2.1e-20)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg33_193"
                     /transl_table=11
                     /translation="MKKKSVIDIEAVISYIENNLDGKVELDTVARYVHYSKYYIHRMFT
                     KTVGMTIHDYVVRRQLTEAAKLLVFSTKPIIEIAFICGYESQPAFTVAFKAMYKITPAE
                     YRERQEFYPLQLRVTLHSKNVKINFSKSDIRLAKMEDISAWMELVRLVIDGYPNLNELE
                     YIEKLKVCIEQRNALILEKQNTVVGVMAFSYDTGSIEFMGIHPQYRNKGIQKLFLDKLI
                     EEYIPDREISTTTYRKHDRADTGYRNELMQLGFAERELLIEFGYPTQRFVRSDHIMEVK
                     NSD"
     PFAM_domain     complement(18402..18560)
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_193_0046"
                     /evalue="3.70E-04"
                     /label="ctg33_193"
                     /locus_tag="ctg33_193"
                     /protein_end="226"
                     /protein_start="173"
                     /score="20.8"
                     /tool="antismash"
                     /translation="QRNALILEKQNTVVGVMAFSYDTGSIEFMGIHPQYRNKGIQKLFL
                     DKLIEEYI"
     PFAM_domain     complement(18756..18995)
                     /aSDomain="HTH_18"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12833.9"
                     /description="Helix-turn-helix domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_193_0045"
                     /evalue="1.90E-19"
                     /label="ctg33_193"
                     /locus_tag="ctg33_193"
                     /protein_end="108"
                     /protein_start="28"
                     /score="69.8"
                     /tool="antismash"
                     /translation="VARYVHYSKYYIHRMFTKTVGMTIHDYVVRRQLTEAAKLLVFSTK
                     PIIEIAFICGYESQPAFTVAFKAMYKITPAEYRER"
     CDS             complement(19270..20442)
                     /locus_tag="ctg33_194"
                     /transl_table=11
                     /translation="MLDFIGGEPLLEMDLIDKMCDYFILRMYSENHKWFPNYVFTFSTN
                     GVLYGKENVRNYVNKHGEHCAFSISIDGIKEKHDMTRKKIDGSGSYEDVIKNLPMYLEE
                     NYNPSTKSTFASADLPFLKDSIIHLWDLGFKDVESNLVYEDVWKAGDPEIFEEQLKELA
                     DYMFESGRYKTVSVEYDTQGMPTRLESVVISTQHDPDITQEQLQKDIKKYVLDAILPPE
                     MVDDNTKIFINPTGRFVVGGPHGDSGVTGRKIIVDTYGGMARHGGGAFSGKDCTKVDRS
                     AAYAARYVAKNIVAAGLAKKCEIQISYAIGVAEPTSIMIDTFSTGRISDKKLSEIVSEV
                     FDLRPAGIIEMLNLRRPIYKQTSSYGHFGRQDLNLPWEKLDKVKILKKYL"
     aSDomain        complement(19276..19923)
                     /aSDomain="TIGR01034"
                     /aSTool="tigrfam"
                     /description="metK: methionine adenosyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg33_194_0005"
                     /evalue="3.60E-99"
                     /identifier="TIGR01034"
                     /label="ctg33_194"
                     /locus_tag="ctg33_194"
                     /protein_end="389"
                     /protein_start="173"
                     /score="330.2"
                     /tool="antismash"
                     /translation="TVSVEYDTQGMPTRLESVVISTQHDPDITQEQLQKDIKKYVLDAI
                     LPPEMVDDNTKIFINPTGRFVVGGPHGDSGVTGRKIIVDTYGGMARHGGGAFSGKDCTK
                     VDRSAAYAARYVAKNIVAAGLAKKCEIQISYAIGVAEPTSIMIDTFSTGRISDKKLSEI
                     VSEVFDLRPAGIIEMLNLRRPIYKQTSSYGHFGRQDLNLPWEKLDKVKILKKY"
     PFAM_domain     complement(19306..19725)
                     /aSDomain="S-AdoMet_synt_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02773.18"
                     /description="S-adenosylmethionine synthetase, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_194_0048"
                     /evalue="2.70E-70"
                     /label="ctg33_194"
                     /locus_tag="ctg33_194"
                     /protein_end="379"
                     /protein_start="239"
                     /score="234.7"
                     /tool="antismash"
                     /translation="VGGPHGDSGVTGRKIIVDTYGGMARHGGGAFSGKDCTKVDRSAAY
                     AARYVAKNIVAAGLAKKCEIQISYAIGVAEPTSIMIDTFSTGRISDKKLSEIVSEVFDL
                     RPAGIIEMLNLRRPIYKQTSSYGHFGRQDLNLPWEK"
     PFAM_domain     complement(19729..19923)
                     /aSDomain="S-AdoMet_synt_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02772.18"
                     /description="S-adenosylmethionine synthetase, central
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg33_194_0047"
                     /evalue="7.70E-16"
                     /label="ctg33_194"
                     /locus_tag="ctg33_194"
                     /protein_end="238"
                     /protein_start="173"
                     /score="58.4"
                     /tool="antismash"
                     /translation="TVSVEYDTQGMPTRLESVVISTQHDPDITQEQLQKDIKKYVLDAI
                     LPPEMVDDNTKIFINPTGRF"
ORIGIN
        1 aagtggaaat tacaatcgcc agagaagttg gtccgcaccc ggcagcacca acattgcttg
       61 ttccataagg aaggcttgcc cacggttctt ctgtctgatt aaaataagtg acttctttca
      121 cacagttttc aaccgtatca tatcggattt tatctccggt aacatcaata tttccaatca
      181 atgaatcatc aaccccacct cctgtcacaa aatccgtcca tgaaaatagg gaaaatattg
      241 cttcctttag cgcatcaact ccatcctgca taatctgaag aacccgtaaa accaactcaa
      301 atgtcccctg atccagtaca tacttatact catacttgtt tccgttttga gataactgtg
      361 aactcaatag taaagccaat gtatattcca ccgttttttc acctacttct tgctcttcca
      421 tctgcacatt ctgtccactt tcctttaaag tcagataagt ttcttttgta atctctgtct
      481 ttccagcttc tgttatcaca taatagactg tttttacaga tgactgctct cccgtattgc
      541 ttacagacca tgaaaagaat tgcggcacat attctgtcac cgcatttttt aacagttggt
      601 atgacttttc caattcctct ggactccatt cggtatcaga ggaacttccc gttccactgg
      661 gctgttccag tatttgaata tatcccatta ccttttttac atggttctgg gtttctgtat
      721 acggtggaat ttgatatccg gcattgatga ctgcctgcgg acctgcatta tatccagcaa
      781 taaccaattc caaagcattt tcatatccct gaaacatttc cataagctct gcaacgtatt
      841 tggctccccc catgatattc tgtctaggat catacggatc tgttactccc agtgaagcag
      901 cagttccagg cattaactgc ataatgccaa ttgcacctgc accagatact acattaggat
      961 caaagtttga ctctactttc cccattgcaa tcaaaagtgc taccggtaca ttataggtat
     1021 ttgccgcttc ctcaaaaaag gcatcatatg gactgctcaa atctgtatcc aagttcatgt
     1081 ccagaccacc agaatatccg agaaaagatt ttcgcgtggt gctgtcccac ttttgcatca
     1141 gtaaaatccc cacataataa gataggttat cttttaatct tgtctcatat tcatctacga
     1201 ttgtcagttt atgttctcta taatttgcct gataatctgc ctgtatttcc tgcagcttca
     1261 tatcatgttc ctgagaaata atagatagca gctctgtttg gtatgcttct acttccagca
     1321 cctgttcaat cctgcttctt attgctgcaa gttcttttga ctgcgcttca tttgcaaaag
     1381 aattagcatc cataaatcca agataggaaa acagaatacc aatgaaattc acaatgatga
     1441 ataggaacag taaaattgcc gccataattg ctgcaactac tttttggaac gtcttatttg
     1501 tcactaaaaa tccaacaacc gttccaagag gtcctgcaat tgctgttcca atggtacttc
     1561 cagccacact gcctcctgcc gctgttgccg tagagtaagc tgcctgagca ccttttgctg
     1621 cattttttgc attttttatg ccatctgcaa cctgttttgc ctgctttgct gtttttgctg
     1681 tctggatagc agcattggct gtattgtcaa gaggtgatgt atcatgcctt tcttctgcca
     1741 ttttacacct ccctaccagt ctttacgctc atcatatccc tgtcgcaatt cacgtctgga
     1801 ttttggaatt tctggaatcc catcttctag tttcaaactt ctttctgcct cgtttgggag
     1861 aacactttct cttaaattct gtccttgtat cagcatctct cgtcctaaaa catcgctagt
     1921 ttccatttcc cctgttgtcg gaacatctga aattcttctt tctgcccctt gtccaaactc
     1981 attttgactg gagagacaat cacctgttgg atgttccctt gtttcctctg aaaactttgg
     2041 aattacggac tctcctttag aagtcgaaac accactttct ccaatttcgt ttaaaatacc
     2101 agatccggaa gtctccattc cgcctgaaac ttcctgtgca gaatattccc ttccagcact
     2161 gccgcttgtg accccttcca aatccatttc actttcacca atggttccac catccagatc
     2221 cataccaacg gatgtagctg tttcctcttc ccttggataa tctaaagctc catctgcttc
     2281 tgtcagtacc tcttgtccat tttcagattc tactggaata ctatctgtat ccaacatacc
     2341 ttctgcataa ctgcttccag tattttctgc ttccatagca ggaacttctg ataccgaatt
     2401 ttccttcagg tcagaaagat ttccttgttc ctgtgtaggt tcaatttctt ctccttttac
     2461 caattcaccg ccttctccaa gtccataatt ttctgtacta gcttctggat ttttcatttc
     2521 ttcttgctgt gaagtaattc ccatttcgtc cagaatattt tcctgatctg aaactgtgtc
     2581 tgctgtttta ccatcatctg cattgtccgc atacccctct tccaacggat ttcctgatac
     2641 gtaatcttct cccatttctt ccatatccat aggatttcca gtactcattg gtattggacc
     2701 tgcaccatct cccattccgg aagaagttcc cattgcttca ctatttcctg tatgttctcc
     2761 attttccata ctctcagttg tactatgact gctatgtccg aatgagaata atctgctggc
     2821 tgccatcatt aacccaaaag cgcccattcc attcgacatt cttccaagat taattccaag
     2881 tgaagccata taagaatcca ttttaaagca cacttttgaa aatccaatca aacataaggt
     2941 tgcaataaaa aactttgtaa aaccatagtg gcttgcggtc aaatttccat acccgcttaa
     3001 aaacattttc atacaccacg cattcataat gattaaaaca acttgtccac caaacatctt
     3061 gctccaggat gctaatacat tattcgttgc cttagagcca cctgtcgaaa atgccaaagg
     3121 tgcagtatag gaaaaaacac ccaacagaac ataccgttct gcaatgataa acagcatttt
     3181 aaagtaattc catgcaacga caaactgcat aatcagtaat agtatggaaa tgctcaatcc
     3241 atcaattcca agacttgccg atgcctgatc cagagaagat acaaaatcag aaaaactttt
     3301 tacttcaatt tctgttcctg ctacccactg ataaggagta ccagccactt ccaaaatata
     3361 atttgctact ggtctggcaa agagcaacat aaataaacat aaaaagctcc tgcagaccaa
     3421 ctccaccgga tcttccgctg caacaccgcc tcttccaaac atggttttga ataactgcca
     3481 gattaaaatc agcaatagga ttgcaatccc cataggaaga atagcatttt tatacaaatc
     3541 ttttactact gtaaataagt cttcaaacaa actcaaattg caggatagta aatctgtgaa
     3601 cattccggta atgaggtcca tcatgtctac taaaaactgt gaacaaattt cccggattcc
     3661 ttcaatcaat aattctaata accagcccaa ctaacttcat caacctcctt ttcccgggag
     3721 ggctccggta tattatgttt tttaaccagt aaagttctgc tgtggaacga gaacttccat
     3781 gtagtttaca atcgctccaa gtaccattaa cactgcccaa caaatgacaa tgcgtttcag
     3841 ccacgttctt gactcatcca ctgtttttcc gctttttgaa aaattcatca aaaacaaaca
     3901 cactgctgaa cacacaactg ctgcaacagt agcaattcct actacatcgt tatacacttt
     3961 ctgcatagcg tcttttgcca tagaaaagat gtccgcagca tatactggct gtgtaaacca
     4021 cgccagcatg gtaatcatga aaaatcccat aaacataaat tgaggaatcc aggcagtctt
     4081 cattttaaac tgtggtttcc tcaatttctc tacgatatgc acttgtaatt ttttatgaaa
     4141 caaacatcat cctcccttcc tctttatttc agggcaacaa aaaaagcaac catttctgat
     4201 tgcttttttc cctgattatt cagttttgcg gccctccatg tagatactca catgcacaaa
     4261 actttacgtt atcattgtaa aactttaaga atccgatgtc aatttcagag aggtcgcaat
     4321 gttataggaa accagtctta tttttgtatc acttataaaa acatatacac agtaagtatc
     4381 gtaatgacat ttttgaaaaa tctattccaa aaaatccatt taacaatatt ttaatagaat
     4441 aaagaatcta gtttttacaa acctatgata ttttaatact gaaatctaaa ataaactatt
     4501 taggaggtat cataatgaag aaaaaaatac tcacattatt attaacagtc acagctttag
     4561 gtgtaattcc tttttcagtt tatgctagtg acaccgacac tgccaaagag aatgaatgca
     4621 acgaagtgat tacaaatcaa aaaattatta atgagaaaaa tccagacggc acaattacac
     4681 aggctggatt agtaacattt gaatatcagc caagctcatc tgacttaaaa gcaggaggat
     4741 gttcatctgg ccatcacacc aatatcgtca acaatggaac accagacact acacgcatcc
     4801 acggaaaaac acaccctgga tattgccagg taaaaacaac aacctattgg agatgcacaa
     4861 attgcaacac aaccggtcat gatgataaat atacacttgt ctggtgtcca agtgcagata
     4921 taagtggtga tgaacctggc aatgaacctg gcttacaata aacaaatttt ataggatctc
     4981 aataatttta catagaaaaa gagtggttca tttagattgt atcaactatt taataaatat
     5041 aaaatccagt gtatttgtga actctaattt tgaactatga aatagtataa ttatggtaat
     5101 tacatttcca gttcaaaatg taacacacaa aaaaaggagt accagaaatt cgagagcatt
     5161 tcctcattgc tccgactctg tgtacccctt ttttaataaa ttgattagtc ttctatttct
     5221 ataaggtact tatacatttg ccgctttata ccatgactgc gttgttatct ttctcctaaa
     5281 atccctttta taattttctt tttttctata tcctgatgat tgtttcctta cattcgcttt
     5341 atattcctga taatgttctt tcttatgata attccaacag ttatttctcc atttttgagc
     5401 gagaacagaa tccgtagaac ttagcagtaa taaaatttcc attgggcact gacattcctg
     5461 cggtagttcc ccttcatatt gctcattgca taacagattg taatacattc ctttctgaat
     5521 gcaaagtggc aaaactgctg cgtatacaaa acttttacca aatcggtccg ttgtcctgac
     5581 tgcagcataa tatacctctt ctacaatata agacaaaatt acttctttct ccggtatcca
     5641 tcttcctctt tcttcgtatc ccctttgtct gaaaagttta tcacactcta ctcttatttc
     5701 ttctgaaact gcagctttta ataatctttc attttctata tgaaaacata tccaactcat
     5761 tctattcacc tcttcttatt cttttgaaaa agcaggaaca agaattttaa tacccttctt
     5821 gatcctgccc tttttctacg ctgctgcttt taaactttct gcttcatctg caaaaaactg
     5881 tatataatag gtcttttctt ctccttctac tacaatatga tttacatcca aagcaataat
     5941 ttttttaact acttctgttt ggaatttgtt acctttccag taatagtgta gtggtctacc
     6001 tgtaataact ggaaatacca cccagccatg cgtccatatc atttttttga ttttcttgct
     6061 ttttaccatc cttgttcctc cttttcaaca taaaaaaggc actgactgtc caataacaat
     6121 caatgccatt ctttttcttg tggatatatc cctatcctaa atttttctcc tatttaaaat
     6181 aggactatac ctttgtgatg tcagtctata ctgatatcat aaataactac acaatcatca
     6241 tagcacaata tcttgtgtat atcaatactt aatatacaaa ttattgtgtt cttctgtttt
     6301 cataggaaat tttataatac tttttaaaac tgcacatacc aattcctggt ataaatcctc
     6361 atcaaatttc ccattacttt ttgcgtattt taacaacaaa ggacggtaca tttctataat
     6421 ttcaaatact gcttttttat ccttatttcg tgctttccat aataattctt caaattctct
     6481 ttcctgcatc ttttccttct cctaattccc tgcgaatttt tttaattacg ttgtaatagg
     6541 tattttcagc cttttttcca gatattccta tagccattcc tatttcatca aatgtctttt
     6601 cgtacaatat tcgcagacag agaaccttta tatgcaatgc cgaaaaactt ttcagtatat
     6661 gtaaaagttt attgtctgtc acctgagcaa acaatttttc cgtatcaatc tttccccaaa
     6721 aaatatcgtg tgcttccatc atttcattcc attctattcc ccttccttct acattttcca
     6781 aatcctcttc taaagtaatc tcatgctctt taatcttact tttatcgttc atatagttaa
     6841 tagtggtatt tcttactgca ctctgtaggt atgcactaaa ttcatctata gtagttcgtt
     6901 tttgtttatc cataaatctc ctcctgaaat ctgtttttaa tctataatcc gtttccaggc
     6961 ggagagtttt acttctatgt tactattact tgcttttaag taataattac aaaaaagctg
     7021 ctagaattct tctaacagca taatgttcct ttactactct aattatgttt ttgcatcaaa
     7081 agacagcata aataaactta tatatttttt tcattatgta tatatctttc aatcatgcac
     7141 tcttctattt cctccattct gtctgtcgaa ttttccaact gatcaaactc tccaatttcc
     7201 tcttggtcca aagcatcttc aatcatttct gttaaatctt cttttttaca tccaggtttg
     7261 aatatgtgtc cacaattagg acaaatccga taccaaataa taatctcaat tccacatttc
     7321 gggcaaaact ttttttgata tctctttctc actaaaagaa gaataagaac catttcctgc
     7381 aaaagtaaca ataatgtcaa cagcagaaat gcccatttct ttccattcca tgccatcccc
     7441 acaagcagtc cttgtaaaat tgtcattcct cctaaaatat actctactct attccgcatt
     7501 tttcctctct ttctaaagtt cttctttata gaaactttta ttttcctcta attcctcttt
     7561 ctccatttcc tgaagcaatt ctttattttt ctgtatcatg agaatatcct cctcttgcag
     7621 tgttggaaga aattcatctt gtaattgtac gactctgttt ttctttggta tatccagctt
     7681 cttgtctatc accgcctgct cttttgaaaa ttttccttct atgttttgat gatatgcaag
     7741 aaccgccttt acaacaaact ttgcttttct atgccctaac tggtttagta ttcttgcaac
     7801 ttcctgatga tccgggtcct cttcatcaaa tcccaaggaa aatctgtacg gattttgttt
     7861 tgccatacgt cctcccctta atatcccgct ttttctgcca tatattgttt gataaagcct
     7921 tttacatttg ctctcggatc atcaacaaca taatatgttg aatgatatct tttccaaact
     7981 tcatcaataa tatcctttaa aagaaccgtt ccacctccca caaaaacagt cactgttgtt
     8041 cgaaaatcaa taccaaattc taaaaaagaa cctaataaat cacccatata ttctgcagca
     8101 atttcaaacg ttcttcgaac aactagttct gaatacggtg ttttcctttt aaaaagaata
     8161 ttatcgatat ctgcttcttc cagataaaga ttaaagcgct gccttattcc taccataatt
     8221 cttttataaa gcataataat cccttccgga agggaatcaa ttcttgttct gtctactact
     8281 ccataccgga ctaacagata atctactgta aatcctccaa tatctatcag cagaaccttt
     8341 ggctgttctt gtaaatagag ctgatttgct accaaaatgt acgcagaata tccctgcata
     8401 tatacattta cgctctcata gcgtattctg tatggttttc ctttatagga aaaataaacg
     8461 gcttttcctt gccgccaaaa atattcccgg aattttcgga tctgttttcc gtaatccccc
     8521 ggcggaagtc caactaataa ctggatcgga atggttcccc cttcataaat accagtttct
     8581 attccttctt tttccagttc cttggctact ccgagtaatg tcaaaatata atacctgtca
     8641 tcaatggttt tatcttccaa ataggaaatc ctctgattac tttccaagta gttaatccct
     8701 ttaaaaaaaa tcccttcttc tccaggaaga attttttgtt cttttctttt aattcccgaa
     8761 tgaaaaataa aatggttggt tttcatcatt ttatttcccg tatctatgct cataacaact
     8821 cccatgtttc tcctttccag ccctttgact attttattta cctattcctg ataattctgg
     8881 tttacctgtt tcaatatttg ctgatttttt gtttcgtatc cccataatat attgctgact
     8941 gcctcaaaag ccttatctcg ccatctaaaa taagtggctc tgtgcattct tggtatccgt
     9001 ggaaaatgcg gctccagttt atccagaatt tcatctgtat tctctgctct ataagctgac
     9061 atataggtat aataaagtac ccaataatac ttttcgccct gtgggtgata tttcctcatt
     9121 aactctaccg cctcatcaat cagcttcaga tacttattgg cctgattgat agattcgatc
     9181 ctctccctca tatcttccat atccagattg atatccattc ctgcctggta aacactatct
     9241 aaaaattcat ctacatcggt gccatactct gtatgaaagc attgctttac ttgattgatt
     9301 tttatctgca ttttccaatt cacagatctg tatattttaa atagagatat aatatcatgg
     9361 taaacttcat tatcttttcc ttttacatct tttgatacca cacccgattt tctcatataa
     9421 ttctaccctc tcttctgttc cttaaaatat ctttctatac tctcatctgc tctcttgcct
     9481 gctataacag acgtacataa gatgcaagca atcatactga ttgttataat acataaaatg
     9541 ataactgcta ttttaatcat tttcattctc cttatgtccc tcatctttta aatcttccac
     9601 ctggaaattg atggatcact gctattattc ttgacagaat taaatttact ctatgaaatt
     9661 atcaaggtgc tcctactata taccaactaa aaattcatgg attttctgta aaaaagggca
     9721 aaaaaaaagt ggtattagaa attttctaat ccacttttgc aataagaaca aaatattgct
     9781 actctatgca taagttatgc tcgtaccgaa aagacaaatg caaacatttt attctctttt
     9841 aagttttaca gttattttct gattttgggc acagtttact actttcgcca aacgagtttt
     9901 cttattcagt cgttgttgat ttaggcagtc ctaaactctc tttgtttgtt gaaaaataat
     9961 atcactttca ctaattaata atatctccac ttttacataa ttatcctcta cacctttcta
    10021 tttgattttt tgcttttcct aaaatcatcg atataatgat aattcctaat gtatacacaa
    10081 tggtaaccag atattttagt atattagcta gataaaaaaa acatacagaa aatgttataa
    10141 ttattaaagt ctgtcttatt ctgtttgaaa atacattttt ctccttctca ttcacagggc
    10201 ggtttatatt ttctacaggt ttcatgtaat atagtataat aatttcaaaa acagaaatta
    10261 ctaaagaaaa ctccttcgat ataggaaaat acttaatcat cgaaagtgta aaaaacacaa
    10321 ctaaacatga acaaaggaaa cacaccttaa aactattcat gtgtaacccg ccgacaagtg
    10381 atcgcaaaga aaaaaataat aaaaaaaagg ctgtgcattc ccaaaacatc tgcatcttta
    10441 tagctaatat ataacatata accatacagg ttaataattc tatccctata agaaatccat
    10501 atttatatat ttcataatct gtttcagaga ttgtgttttt tttaactatg tagtcggtta
    10561 atagtttgga tagtttttcc atatcaattt ttctttaatt tctgtaaact atccggcatt
    10621 ggcggttgat gatagatgca cacacatcgg ctattaatag ccattacact aaataccatg
    10681 gcaatacttg ccattacact tgcgtgattc ttcataaaaa atttaatttt cctcatttta
    10741 tcctcctata ctataaagtt gactttgaga tattaaaatc attttgtttt agctattata
    10801 gagaaatttg aaattaaaat ttttgttttt caataactca taaaaaatag ccgatttcac
    10861 cacatcgtcc acttcgattt aatctttaat attatactac catcaacaac tattttattt
    10921 atctcgtaat ttttacgata ttatttgtaa cttttacgat aaatcacata aaatcacttt
    10981 aatagtaaag actttttgtt tcgtttctac cactactgaa ccgtgatatt ttgttgcaac
    11041 tttttgaaca gattctaaac ctattccatg atacccagtt tctgctttac ttgtcacaat
    11101 tttaccgttc cgatttttaa ctaatttacc attgtaagca ttaacaactg taattatcaa
    11161 tacattcatt tcaaatttca taaataactt aatataacgg ttatcttctg tcacctgtaa
    11221 cgatgcttca attgcattat caagaatatt ccccaatagg atacttaaat cagcactata
    11281 aaaaggtagt tgcattggta tgtgaatatc cacattaaac tttatttttt cttttaaagc
    11341 aattgcatat tttgcattaa tcaaagaatc aacaactata ttatctgttc ttgatattcc
    11401 aagattgttt agtggtacta tattaattaa ttttcttaaa taatctattg ctgactcatt
    11461 ttgattatta tctaacattt caataagtac aataacgtgt tgctttatat catgacgagc
    11521 attcctgaag tccatcataa tattctcttt ttcacgcata tgttgtgtac ataattctaa
    11581 ttgttgctca tatacggcat tatatttttc tagttccttt tccttagaca tgaccagata
    11641 cagtttaaat atgacaatgt taattaataa aataattatc aaacttgtca gagattcttt
    11701 gatgtgaacc tttttgttaa tatcaacact caacataaag gtgttatata caacgaacat
    11761 gcttcctatt ggtataagta ataatgtaat attatatttg tttgataaat ctttaacatt
    11821 ttcattttgg aaaaattttt ttaaacaaat aatcataaat agtgtgaata attttgaaaa
    11881 caatgatccc caaaattgcg gaaccatgta atgtattcca cataaaacga acatatatcc
    11941 aactaaaaac tccgctaaca tccatatcgt attaataaga actgaaaata caattttttg
    12001 tagaattcct ccctcatatg tatttataca gagcatactc acaagaaaaa cattaatcat
    12061 gacatttata tatgccggca atacatttgt tcttcccaat atgaattgcc acataaaata
    12121 aaatatccaa aaaaactccc ctataatccc tcttttgtct tgttcaaaaa acgtttcaaa
    12181 ataaattttc aatatcacaa tggatatcaa tgtcagcaat aagtctgcac atgctcctcc
    12241 aaaataccta aacaataata tcttcccctt ttaatgcaca ataaagttca ctcacatttt
    12301 ttcttctgtt ttcactgatt gctaatgttg ttccatcaat taattccata gagtcataaa
    12361 tatatgcagc tacaaattta ggattaacca aaaatgattg gtgcgttcta taaaaatatg
    12421 tgttagcttc atttaagcgt ttctcgatat cattcaactt tccataacat tttctatttc
    12481 ctttttttgt aataatataa gtgactcttc tatcgctttg aaaatacatt atctcatcga
    12541 taggtatcct gtatgatatt ttgttatact gatactgaaa atattgaggg tgatttaata
    12601 tctcattttt ggcagccaga aaatatcttt gaaaaacatc tggaacaata ggttttgtta
    12661 taaatctaaa ggcagatact tcaaatactt cttttgcaaa actttcatga ctggtaacat
    12721 aaattatcaa aactttttta tcaattctac gtataattct agcagcctct acaccatttt
    12781 gttttcgcat ttctatatca agataaataa tatcatatct tttccctttt ttaatataat
    12841 caactaatgt actgccatca taaaacacat ctatttcaac cttaatagca acaataagtg
    12901 atagcttttc taacatcttt tcaatatctg ctgcaattaa tatatcatca tcacataccg
    12961 caatttctaa cattttttcc ccttcaagtt atatctagtt ttagttgtct acgtctcgaa
    13021 ctaaattcaa agcatgtttt atcaactgct ctatgtcata tcttttagtc ctaggacatt
    13081 ccattaacac tttatcaagt gaaaaatctc ctcttttaac ccccgttaaa agatagttta
    13141 tatcaatatc caacttttta tttacaatta ccagcttatc aagcgatagc ccatgaatgc
    13201 ctctttcaat ttttccataa taagctgaac tcatttctag aatttctgcc atttgttctt
    13261 gtgtataatt caattcaatt cttaatatcc gaagtctttt tcccatatca atgtacaagg
    13321 gtttttgact ttttcgtaaa tatgaattat tactgcttgt ttttatttta gactccataa
    13381 attcacctct gtataataac aatatatata tcatacacat gcaaatgtga cttattaaca
    13441 catatatact tcttatttta ggtatatata ttacccattt aggagtcttt ttatgatata
    13501 caacccactt atatgcaaaa ttaaattata cagtaaaaaa ttaacactta atgtattatg
    13561 taaaaattaa aaggttataa gtaatttttt cctaaacaaa aatgtctcat caacgaaaca
    13621 acttctctaa tcagtataat tatcgtgtta gatcatcttt ccttttttat aataaccaaa
    13681 taattttatg atattatata taaatgtggt ttacgggacc cagtgtccac cattccgttt
    13741 tagaacggcc ggtttccgag gtaaaacagt cgttttacct cagtcttcaa tccgagtcaa
    13801 tagcaaaagg gttaaagccg gcataaatgc cccattgaca gtaagcgcaa aataattcga
    13861 tggattgctt tgccctaaaa ttcagtccat aataatcatt agagaatgca agcactttgc
    13921 ttcatcttct gttgctagaa atgataggtg agagcctctt actcgattcg atttatggag
    13981 gactgctcat gagaagcaaa agaatacctg cagaagaaca ataccgtctc atcatggaat
    14041 gccgtcaaag tggattgaca gatcatcaat ggtgtgtgga acatgacatc aaaccaggaa
    14101 ctttttacaa ctgggtaaaa cgattacgtc aaaaaagttg tatggattta ccggcatcaa
    14161 ccggacgcag ccatagcgct ccggaaagtc aggaagttgt cagagtggat tttcatgaca
    14221 ccgacacact ttcctatgaa cagccattaa atatgatccc ggcatctacg aaaagaaaca
    14281 acatttccgt ggcagagcca atgaggctgt gctgaatgag ccggagcgta atccggaaac
    14341 agattcgatg aacagttgga acaactcgcc ccatgaagcg agactgtgaa agctaactgt
    14401 caaaactaaa atagaggaaa acgcttgcat ctatcatttt ggtgcaagcg taatttacga
    14461 gtaacgtagc aatattttgc gcttaccatt gacacgattt caggctgtag aatacagtaa
    14521 tcaagcagaa caaaggatta ttctgctaag acctattcaa tggctgtttt tttcttaatt
    14581 acgtacaatt ttaccagtca tagtcttttc tattgcactg acaaattcta tttttctagg
    14641 atatttatat ggtgcagtag tggttttcac aaaatcttgt atttcttttt tcaattcctc
    14701 tgttccaacc ttttcttccg ataatacaat gtccgccttg attatatttc ccctaatttc
    14761 atcgactact ccatagactt tacactctct tatataattt aaatttgcaa gtacactttc
    14821 tatttcataa ggattaattt tatatcccga agattttata agggtatcat ttcttcctat
    14881 ataccagtaa gctcccatcg cgtctctata agccaagtca ttagtatgat aatatccatt
    14941 tataatatga ctagtttctt ttttttcact aacctgcaaa tatgatgcca atccgattgg
    15001 tatttttttg cgacaatcaa ttactatttc tcctacctca cctatttctt cagaagttat
    15061 aatttctcct gtattcttca ttaattcgat tttgtatata ggatttggat atccaatact
    15121 tccagtatta cattttcttt ttttaaaatc agctataagt aaccctgttt ctgactgtcc
    15181 gtatccattt gcaatcttta ttcctgtcaa taaataaaaa cgatttatta tatcctttgg
    15241 aagtatttca ccagctgaac aagcacatgt aattgaagat aaatcatatt tttttatctc
    15301 cgaacgcaat aacattctat acattgtcgg tggcatacat atagtattaa ttttatattt
    15361 ttcaatcata tgtaatatat ctgaaccttc aaatttcctg aaatcataca cgaagacaca
    15421 tccgccggat agccacggtc cgaataactt cccccataat gcttttcccc atcctgtatc
    15481 tgaaatagtt aaatgcaatt tatcttgttc tatattattc caatatttac ctgtaatata
    15541 atgtgctaga gggtacaaat tatcatgtac taccatttta ggtgttcctg atgttccaga
    15601 cgtaaataaa ataaacatta tatccatcgc attataatct tgaggtttca ctaagtcatt
    15661 agaaaacttc tcattttctt tatctatatt tatccaattt ttatttccac ctcgaataga
    15721 gaatctaagt attgtagtat taacgcactc gtttatcact ttgtcggttt ctttttgaaa
    15781 atcctcgcca tatagtgaga ttattgcctt tgcgttagat atatttattc ttgctttaat
    15841 atctacctct cttaattgac ttactactgg aattggtatt gcaccaattt ttattagtcc
    15901 taaaaaaata taccaaaatt gatatgctct tcgtaacgct atcaataccg catctccttt
    15961 ttttattccc tgagctgcaa aaaaatttgc cattctatta gaacagtttt ttaattcctt
    16021 atagtttatg gatttttcta ttttattttc atcaatatgc aatattgcta tttttttagg
    16081 atttatttct gctattttat ctatgatgtc atatgcaaaa tgaaactttt cgagattttt
    16141 aaatgatact tcactaatct tattctcaat tattaccgta tttatatagt tttccactac
    16201 attttcatct aaattcatat gtactactcc tcactgttaa atatagtcta atcatgaccg
    16261 acatacttta acatataaat ttataataat tcttatcttt gtaattattc agaacttata
    16321 tgtaatattt tctgattttt ttcttctcat gtcagtttta tgggattaaa aaagaaggtt
    16381 atttgcacag ttgtattaag tacattattt ttcccaaata atctacattc aacttaaata
    16441 tataattcaa ccttctcttg attatcatgg tatatcagaa ctacctgtcc gataaagtca
    16501 gaaccatgat tccgccaacg caaagccact ttgagtttgt caagattaga tctgctttaa
    16561 cggggcatta gccgtcttta taagcactgc tccagtacgt aatttatcga aacaaaatct
    16621 gtagctttta ctgactctca ttctctggaa tgatatctct tataatccag ttcggtggtt
    16681 cacagtacac cagtataatc actcctctaa aaagctacta gtttttcata cttttaaaac
    16741 acctcgtata aaccataatc agacaaaacg agcgttttta cgtttacgca cgataaacta
    16801 agaatttcca caaatagata tttttgtatg atgaaactac cagatgtata atttgtccta
    16861 acattactca agaaatacag acctctctct taaataacaa tcattttttt atataaaaaa
    16921 atataacccc ttcttttcag agattatatt ctttatcata taaataatta ttgagttatc
    16981 tgtaattgcc attttgtaaa ataaataaca gacacataag ctattattta taaagttgat
    17041 gatcaaaacg aagaatcatt gcaatcatca tcactagcac tcctgaacat actataatcc
    17101 attctaaagg aattatatct gccatcggtc caaaaatcac cattcctatc ggaataaagc
    17161 cagaatacat agatcccatt aatccgaaaa tacggccttg cattaagctt ttcacatttt
    17221 cttgaatcaa tgttgtaatc gaagtttgta ctatcgttag agcaacaccg tataatgcca
    17281 ttaaaataag atataatata aatttttttg tcaatcccat gccaacagcc attattccga
    17341 agataaatag cccaaataca agagtattta tgcggctctt aaaacctcgc cataaactca
    17401 tcaataatcc acccattatc attccaaaaa aaccaattaa ttctacagct gttagatacc
    17461 aatatgtatt gccataaacc ctgttaacta aaagaccagc aagaaatcct gcaggaacac
    17521 acaaaaaagt gaataatcca taaactataa gtaattttct aatcagttta tctgaaaaag
    17581 caaaatgaat tcccatacgc atatctttta taactgaagc tgatttttct atgcttcttt
    17641 gtttaggaat caatacacag gaaagtattc ccaccccaaa tactgctgtt aaaatatcaa
    17701 taattaatgt ggattgtaat gtactaagtg ataataacaa acctgcggct gcgggtgccg
    17761 caaattggac aagtgattgc atagtggcat taataccatt aaaacgcata agctgagact
    17821 ctggcactag ttgaggtatt acagcgttaa cagcaggtgt ctgtattcca gcccctactg
    17881 agcgaattat tgacattacg agtaaacctc caagtaaaaa tttttcttct ctaataaaag
    17941 gcattgctaa catcataata aatgtaactg ctgcaattga tatatctgca ccaataatta
    18001 atcttttacg gctatatcta tcggcccata caccaccaat aaaagacatt aagaactgtg
    18061 gaagatatga acaaatacta aaagctgcta cccacactcc agatgaagta ttaagcgtta
    18121 cataccatac aattgccatt tgcacaagtg tagatccaaa aagtgtaacg cattgactta
    18181 taaggaaaag tactgtccta cttttccaat taactattct cttttcaatc actattttta
    18241 acctccatta tatgatcaga acgtacaaat cgttgcgtcg gataaccgaa ctcaattaat
    18301 aactctcttt cggcaaagcc aagttgcatt aattcatttc tatatcctgt atctgctcta
    18361 tcatgcttac gatatgttgt cgtactgatt tcacgatcag gaatatactc ttcaattaat
    18421 ttatccaaaa aaagtttttg aattccttta ttacgatatt gaggatgtat tcccataaat
    18481 tcaatacttc cagtatcata agaaaacgcc ataaccccaa ctacagtatt ttgtttttct
    18541 aaaataagtg catttctttg ttcaatgcac acttttagct tttctatata ttctagttca
    18601 ttcaaattgg gatagccatc aatcactagc cttacaagtt ccatccatgc tgatatatct
    18661 tccatcttag ctaatctaat atctgatttt gaaaaattta tttttacatt cttactatgc
    18721 aatgtaactc tcaattgtaa gggataaaat tcctgacgtt cacgatattc tgctggtgtt
    18781 attttataca ttgctttaaa tgctactgtg aatgctggct gactttcata accacagata
    18841 aatgctattt caattatagg ctttgtagaa aaaactaaca attttgctgc ttctgtaagt
    18901 tgtctccgta ccacgtaatc gtgtattgtc atgccaactg ttttagtaaa cattcgatgt
    18961 atgtaatatt ttgaataatg aacataacgt gcgactgtat ctaattctac ttttccgtca
    19021 agattattct caatatagct tataactgct tcaatatcaa tcactgattt ttttttcatt
    19081 tttgtgtcct cctttccgtt gaatagaata acagaatctt aaaccgtttt ttttacaatt
    19141 cttgctatgt tatttaatga aataacttta tatgcaaata tagcaaaaaa tcaatataat
    19201 ttatctgtga agaagataaa atcaaaccat acttacgctt taaatacgag tatggtttga
    19261 ttttttactt tataaatatt tttttaatat ttttacttta tccaatttct cccaaggtag
    19321 atttaaatct tggcgtccaa aatgtccgta tgaagatgtt tgtttatata taggtcttct
    19381 caaattcaac atttctataa taccagcagg tcttaaatca aatacttctg atacaatctc
    19441 tgataatttc ttgtctgaaa ttctacctgt gctaaatgta tctatcataa ttgaagttgg
    19501 ctcagctact ccaatagcat aagaaatttg gatttcacat ttcttagcca atcccgcagc
    19561 cacaatattt tttgcaacat agcgtgctgc atatgctgct gaccgatcca cttttgtaca
    19621 atcttttcct gaaaaagctc ctcctccatg acgtgccatt ccaccatagg tatcaacaat
    19681 aatctttctt cccgtaacac cactatcccc atgaggtcca cctacaacaa atctccctgt
    19741 aggattaata aaaatctttg tgttatcatc caccatttca ggaggtaaaa ttgcatctaa
    19801 aacgtatttt ttaatatctt tctgcaattg ttcctgtgtg atgtctggat catgttgtgt
    19861 agaaataaca actgattcca aacgtgtcgg cattccctgt gtatcatatt ctacagaaac
    19921 tgttttatat cttccgcttt caaacatata atctgccagt tccttcagct gttcttcaaa
    19981 tatttctgga tctcctgctt tccacacatc ttcataaact aagtttgact caacatcttt
    20041 aaatcctaaa tcccataaat gtataatgct atcttttaga aatggaagat ctgcacttgc
    20101 aaatgttgat ttggtggacg gattataatt ttcttccaaa tacattggaa gattttttat
    20161 tacatcttca tatgaacctg aaccatcaat tttcttgcga gtcatatcat gtttctcttt
    20221 tattccatca atgcttatgg aaaaagcaca atgttcacca tgtttattta cataattcct
    20281 cacattttct tttccatata aaactccatt tgttgaaaat gtaaatacat aatttggaaa
    20341 ccatttatga ttttccgaat acattctcaa aataaaataa tcgcacattt tatctataag
    20401 atccatttcc aaaagcggtt ctccgccaat gaaatccagc ataatactat ccgacatttc
    20461 tgacgtatat ggattgtcta acagaaaatc gataatttgc tttcctgttt cccaattagt
    20521 accataaaag tgtagttgtt agagagtaat taactctaac atctacactt attttattat
    20581 aataagggaa gtagttggta tgacatattg ccattaggat tttcacatcc gtgaatgaaa
    20641 ccgtcagcca tccccttatt ataaacattc atttaagcag gttgaaactc gcaggagctt
    20701 tcgcgtaacg aactaaactg aatcataata agtgta
//
