LOCUS       NZ_HF545617.1          26374 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_HF545617.1 Ruminococcus bicirculans (ex Wegman et al. 2014)
            strain 80/3 chromosome II, complete sequence.
ACCESSION   NZ_HF545617
VERSION     NZ_HF545617.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:29:56
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 622653
            Orig. end    :: 649027
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..26374
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[632653:639027]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16374
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..26374
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..26374
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(426..1970)
                     /locus_tag="ctg2_552"
                     /transl_table=11
                     /translation="MPTVTVIQPTITEEQNTKIRCAAYCRVSSDSEDQLNSFMAQTRYY
                     SQFFENSETEELIDLYADEGITGTREDKRDEFQRMIKDCRKGRIDRIYTKSISRFARNT
                     KDCLKNVRELKSLGITVFFEKENIDTANMTDEMMITIMGGLAQEESTSISQNMRWSIKK
                     RMENGTMKMCNSVFGYELVNGELILNQDEARIVRKIFDWYLNGYGSEKIAQMLNEMGIG
                     KRGRSCHWTGPTVRVMLKNEKYIGDQLFQKRFTTTVLPRKNLPNRGELPQYYYTGCHEA
                     VISKDVFDRVQELIRLRGENKRNESRGNILSKKIKCGECGTTFRMKNCRGKIYWVCRLH
                     TDEIEKCSVKPINQDNIHSAFIRLCNKLWYNYKQILVPFQTALHDLKLRKLSSKTQVMD
                     IHKQTAKLREQTHVLARLKTKGFLDEVKYIEQTTELTAKINKLQAELKKLTRSDDEDET
                     IDQIEMLIDFFEKQSNPITEFDESTFEGIVEKIVVINQHELEFHLIGGLKFNEKIK"
     PFAM_domain     complement(876..1040)
                     /aSDomain="Zn_ribbon_recom"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13408.8"
                     /description="Recombinase zinc beta ribbon domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_552_0003"
                     /evalue="1.80E-08"
                     /label="ctg2_552"
                     /locus_tag="ctg2_552"
                     /protein_end="365"
                     /protein_start="310"
                     /score="34.8"
                     /tool="antismash"
                     /translation="LSKKIKCGECGTTFRMKNCRGKIYWVCRLHTDEIEKCSVKPINQD
                     NIHSAFIRLC"
     PFAM_domain     complement(1080..1400)
                     /aSDomain="Recombinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07508.15"
                     /description="Recombinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_552_0002"
                     /evalue="1.60E-19"
                     /label="ctg2_552"
                     /locus_tag="ctg2_552"
                     /protein_end="297"
                     /protein_start="190"
                     /score="70.3"
                     /tool="antismash"
                     /translation="DEARIVRKIFDWYLNGYGSEKIAQMLNEMGIGKRGRSCHWTGPTV
                     RVMLKNEKYIGDQLFQKRFTTTVLPRKNLPNRGELPQYYYTGCHEAVISKDVFDRVQEL
                     IRL"
     PFAM_domain     complement(1464..1907)
                     /aSDomain="Resolvase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00239.23"
                     /description="Resolvase, N terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_552_0001"
                     /evalue="1.60E-31"
                     /label="ctg2_552"
                     /locus_tag="ctg2_552"
                     /protein_end="169"
                     /protein_start="21"
                     /score="109.4"
                     /tool="antismash"
                     /translation="AAYCRVSSDSEDQLNSFMAQTRYYSQFFENSETEELIDLYADEGI
                     TGTREDKRDEFQRMIKDCRKGRIDRIYTKSISRFARNTKDCLKNVRELKSLGITVFFEK
                     ENIDTANMTDEMMITIMGGLAQEESTSISQNMRWSIKKRMENGT"
     CDS             complement(2034..2162)
                     /locus_tag="ctg2_553"
                     /transl_table=11
                     /translation="MLGFFIGLFVGAFIGMTAMCLCTAAGQADKHENCTDSDKEIH"
     PFAM_domain     complement(2070..2162)
                     /aSDomain="DUF3789"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12664.9"
                     /description="Protein of unknown function (DUF3789)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_553_0004"
                     /evalue="9.90E-16"
                     /label="ctg2_553"
                     /locus_tag="ctg2_553"
                     /protein_end="31"
                     /protein_start="0"
                     /score="57.2"
                     /tool="antismash"
                     /translation="MLGFFIGLFVGAFIGMTAMCLCTAAGQADKH"
     CDS             complement(2175..2333)
                     /locus_tag="ctg2_554"
                     /transl_table=11
                     /translation="MTKFGQAEYGDFMARMFADKLDEILETTEKQNFNRRNTEDIYKEF
                     VSSKDAA"
     CDS             complement(2326..2673)
                     /locus_tag="ctg2_555"
                     /transl_table=11
                     /translation="MLIKRGDIFYADLDPVVGSEQGGVRPVLVVQNNIGNRHSPTLVVL
                     PLSTVKKNKLPTHICIRNSKILPKDSVILAEQIRTIDRSRLRSYIGSLDSGIINKIDEA
                     MKISIGVDFDD"
     PFAM_domain     complement(2350..2664)
                     /aSDomain="PemK_toxin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02452.19"
                     /description="PemK-like, MazF-like toxin of type II
                     toxin-antitoxin system"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_555_0005"
                     /evalue="3.50E-31"
                     /label="ctg2_555"
                     /locus_tag="ctg2_555"
                     /protein_end="108"
                     /protein_start="3"
                     /score="107.9"
                     /tool="antismash"
                     /translation="KRGDIFYADLDPVVGSEQGGVRPVLVVQNNIGNRHSPTLVVLPLS
                     TVKKNKLPTHICIRNSKILPKDSVILAEQIRTIDRSRLRSYIGSLDSGIINKIDEAMKI
                     S"
     CDS             complement(2675..2878)
                     /locus_tag="ctg2_556"
                     /transl_table=11
                     /translation="MKDNDIPEKSDFYKFGVNIPVPTVRLSNKHPCYGCVWYDKNADVL
                     FCPFHNCVRNKKGFEVPQKVAK"
     CDS             complement(3364..3804)
                     /locus_tag="ctg2_557"
                     /transl_table=11
                     /translation="MSYNHGLEEKKFKEQWQKTAEEYRKAGMTEKQIAEIYEFDREVFN
                     SNRRYREKTVGLFDNSNSRTLTVYDDYSTNNRYGWIDEIEDMEVYSQIMSLPEIWREAF
                     TMYIFDGYTQNEISSILLRNQSNISRVIDKIAEILRSQFSNA"
     CDS             complement(4009..4917)
                     /locus_tag="ctg2_558"
                     /transl_table=11
                     /translation="VYCNINLICINGNDRLNYDCGQDRILNLNTPIQAGEYYIKISYEQ
                     SGTYSLNSQFSTSGYSKDEEINSPYQNAKLIESNTLNGHIGYKSNQPNETDTDDFYKLI
                     LNSFQLYTFNLTMDSDLKAKIFVIASDGATEIYSDYGKNKEIKLICPLQSGTYYIRIEC
                     LENYGGYQLQMNSVEIKNLDSEPNNTYQNSIETKADETINGSIGFVNDKKEYDQYDWYM
                     FNINERKHIIINTNSPEPFQYEIRLIGTDGEQTLSYTTCRGEIETIEYDLEPGRYYIRI
                     YSSNYGEYEFSYNLNYDFNDG"
     CDS             complement(5705..6232)
                     /locus_tag="ctg2_559"
                     /transl_table=11
                     /translation="MKRKNIICVASSIFIIILLVCVIIKLTCIVNLDDGSSTSISDAEY
                     LEVSDLRKLYIFIDDDEKNLLEELAKNMILDSYYNNGFNDQYTTIVSNDIFKRLNPNNT
                     GNKFDFELISVDVQCLCSEDKAIVFFTKDCSMQSSSNRIECKIVTDGSILDRLYFEKIN
                     DEWKVVSFLQSA"
     CDS             complement(6229..9942)
                     /locus_tag="ctg2_560"
                     /transl_table=11
                     /translation="MQGKNNFKRILSGIMSVAMAATLLPSLPAVAEDAAEKYPYTMFAA
                     SDTEGAITINANNFCVNGNIATNGTIVSSGNMNVNGTKTENADEEMIYILKKLNYSYFS
                     GDNVETYADDYSFEDLNININNPMDVNGTLELTGNINLNSGIKAVEDVTINGEVKNTNN
                     SVICSETGDINIETSNVNFSGLIYAPYGDINIDTDNLNLNNVIIIGQTITIDCPSINAN
                     YSNSMAELVGTESDIEVELYAFGEYNSDANSIDMEWYTNYKNSSYEIWSSDDNVNYTSV
                     AVVSDATTYQYPITDDFETKYFKVSLITNYGERIESVPFVVTKTEDGYSVDFLDSDGDG
                     LPDIYENMIGTDLNNPDTDGDGLTDYQEVYITGTDPTKYDSVTEGVSDADADSDSDGLT
                     NAQEIELGTDPRNDDTDNDGLSDYDEINIYGTDPLVPDTDGDGLKDGDEPYIGLDPTNP
                     ETFDVPDAEYVSNQTIAENSEALREINTDDSPYKMSIEIESTGYVEGNLKAKETSYSKA
                     IRNDAILGIAPELTCGNSCNISKVVLKFNIADESVDNELNLFPDEPDLQGLKRLTIFKY
                     FEDMNMLLPIETKYDLENNTIYTEVDELGTYCIMDMEKWLANLGIGINEAEPMLMSFEA
                     EAVEDIAAEFNEESTRVEFSEETLAEINDEEDTLTEETFAPAMFAAAQTRGAVTVQTPV
                     DIAFLIQTSGQLEDTFNSQCEMIGNLMDSLIAQYGNGNVRFCLITYNLNGAQALKFTSD
                     GNIWFTNSVAVKMALSAQQYVYTSGYTDRGNAFKLLQNNVIFKETSAKFIFQVMNGSTN
                     VGSMYFDQINTCAKLGINYSELMPAGYSYIDPSYGQQVDNAIKSTGGLNLTYGTNSESS
                     VYNHIVGNVAPPHVEFKAVLPTNWETITLKNILDPNNGANSDNDDLTDWQEVDTESGLI
                     TWDNDGNIQLPTFKDCLEKASNKFYVRNVLETYLKYAPSTIWKVFLNAEILPIHSNPCD
                     ADTDGDGLLDHEEVIYTGYTDPLILYVSSPFSKDSDGDDIYDKYDLEPWIVNESYDRNA
                     VYDYMKKWSGDYDTVGEKYNYSEYPNFSELSDKMTDCTNFASQCLCAGGFKMNNDWYFG
                     KAEGLASHIHGLFSHTGTWDYGWTKSWSVVVDNYNYFRSEEYAMYEVSIGRDESIEEAI
                     SKYDIRMGDLIYFCKEKGPTHTAIISSVQKDEILYAGHTKPRWNKKLSETFDENEDYTN
                     VIIVCLNGRVPA"
     PFAM_domain     complement(6271..6816)
                     /aSDomain="Amidase_6"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12671.9"
                     /description="Putative amidase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_560_0011"
                     /evalue="1.20E-20"
                     /label="ctg2_560"
                     /locus_tag="ctg2_560"
                     /protein_end="1224"
                     /protein_start="1042"
                     /score="74.4"
                     /tool="antismash"
                     /translation="SYDRNAVYDYMKKWSGDYDTVGEKYNYSEYPNFSELSDKMTDCTN
                     FASQCLCAGGFKMNNDWYFGKAEGLASHIHGLFSHTGTWDYGWTKSWSVVVDNYNYFRS
                     EEYAMYEVSIGRDESIEEAISKYDIRMGDLIYFCKEKGPTHTAIISSVQKDEILYAGHT
                     KPRWNKKLSETFDENEDYT"
     PFAM_domain     complement(6907..6972)
                     /aSDomain="TSP3_bac"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18884.2"
                     /description="Bacterial TSP3 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_560_0010"
                     /evalue="6.30E-03"
                     /label="ctg2_560"
                     /locus_tag="ctg2_560"
                     /protein_end="1012"
                     /protein_start="990"
                     /score="16.4"
                     /tool="antismash"
                     /translation="DTDGDGLLDHEEVIYTGYTDPL"
     PFAM_domain     complement(8569..8634)
                     /aSDomain="TSP3_bac"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18884.2"
                     /description="Bacterial TSP3 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_560_0009"
                     /evalue="8.40E-03"
                     /label="ctg2_560"
                     /locus_tag="ctg2_560"
                     /protein_end="458"
                     /protein_start="436"
                     /score="16.0"
                     /tool="antismash"
                     /translation="DTDGDGLKDGDEPYIGLDPTNP"
     PFAM_domain     complement(8635..8703)
                     /aSDomain="TSP3_bac"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18884.2"
                     /description="Bacterial TSP3 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_560_0008"
                     /evalue="1.20E-08"
                     /label="ctg2_560"
                     /locus_tag="ctg2_560"
                     /protein_end="436"
                     /protein_start="413"
                     /score="34.7"
                     /tool="antismash"
                     /translation="DTDNDGLSDYDEINIYGTDPLVP"
     PFAM_domain     complement(8713..8769)
                     /aSDomain="TSP3_bac"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18884.2"
                     /description="Bacterial TSP3 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_560_0007"
                     /evalue="1.60E-03"
                     /label="ctg2_560"
                     /locus_tag="ctg2_560"
                     /protein_end="410"
                     /protein_start="391"
                     /score="18.3"
                     /tool="antismash"
                     /translation="DSDSDGLTNAQEIELGTDP"
     PFAM_domain     complement(8809..8874)
                     /aSDomain="TSP3_bac"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18884.2"
                     /description="Bacterial TSP3 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_560_0006"
                     /evalue="5.20E-08"
                     /label="ctg2_560"
                     /locus_tag="ctg2_560"
                     /protein_end="378"
                     /protein_start="356"
                     /score="32.6"
                     /tool="antismash"
                     /translation="DTDGDGLTDYQEVYITGTDPTK"
     CDS             complement(10001..10156)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_561"
                     /sec_met_domain="TIGR04223 (E-value: 8.7e-15, bitscore:
                     49.8, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAIKKLMLKYGSSLAALALMIGVSSSSQACWWWYNQPKEPEGMK
                     KFVKED"
     aSDomain        complement(10019..10126)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_561_0001"
                     /evalue="6.00E-14"
                     /identifier="TIGR04223"
                     /label="ctg2_561"
                     /locus_tag="ctg2_561"
                     /protein_end="46"
                     /protein_start="10"
                     /score="49.8"
                     /tool="antismash"
                     /translation="YGSSLAALALMIGVSSSSQACWWWYNQPKEPEGMKK"
     CDS             complement(10287..10871)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_562"
                     /sec_met_domain="AgrB (E-value: 1.3e-42, bitscore: 140.6,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKLAKGTACFFVDNKIIEVEDSEVYAYGIELLLSTIFNLIIAI
                     IIALISNEFIPCVINLTAFVTIRMYAGGYHADTHWGCMLTLVCVLSAFILIIKTFSTAT
                     IRFLSPILWVLSVLILYKFAPVEHPNKPISEKKKMKLRKKSLISFFIWTIFCIIFYFVK
                     TEVCFYAVTGIFTLTCAMVAEKIKLLIKSYS"
     PFAM_domain     complement(10335..10844)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_562_0012"
                     /evalue="6.60E-41"
                     /label="ctg2_562"
                     /locus_tag="ctg2_562"
                     /protein_end="179"
                     /protein_start="9"
                     /score="139.8"
                     /tool="antismash"
                     /translation="ACFFVDNKIIEVEDSEVYAYGIELLLSTIFNLIIAIIIALISNEF
                     IPCVINLTAFVTIRMYAGGYHADTHWGCMLTLVCVLSAFILIIKTFSTATIRFLSPILW
                     VLSVLILYKFAPVEHPNKPISEKKKMKLRKKSLISFFIWTIFCIIFYFVKTEVCFYAVT
                     GIFTLTC"
     CDS             complement(11608..12030)
                     /locus_tag="ctg2_563"
                     /transl_table=11
                     /translation="MESIVDYFEKYKYDSIPMIIYSQDDHIIEKCLGKNSEYIDCGEET
                     FDKYFTYMRNKYQKDSPYNVFSFIRVNYDNQGNMLMYFIVKNRKIENDKIRNYYLVYID
                     NEYNGHGSDLAIDNSTIKSKPFSGNWYLWSKDVLNG"
     CDS             complement(12180..16160)
                     /locus_tag="ctg2_564"
                     /transl_table=11
                     /translation="MQGKNNFKRILSGIMSVAMAATLLPSLPAVAEDAAEKYPYTMFAA
                     SDTEGAITINANNFCVNGNIATNGTIVSSGNMNVNGTKTENADEEMIYILKKLNYSYFS
                     GDNVETYADDYSFEDLNININNPMDVNGTLELTGNINLNSGIKAVEDVTINGEVKNTNN
                     SVICSETGDINIETSNVNFSGLIYAPYGDINIDTDNLNLNNVIIIGQTITIDCPSINAN
                     YSNSMAELVGTESDIEVELYAFGEYNSDANSIDMEWYTNYKNSSYEIWSSDDNVNYTSV
                     AVVSDATTYQYPITDDFETKYFKVSLITNYGERIESVPFVVTKTEDGYSVDFLDSDGDG
                     LPDIYENMIGTDLNNPDTDGDGLTDYQEVYITGTDPTKYDSVTEGVSDADADSDSDGLT
                     NAQEIELGTDPRNDDTDNDGLSDYDEINIYGTDPLVPDTDGDGLKDGDEPYIGLDPTNP
                     ETFDVPDAEYVSNQTIAENSEALREINTDDSPYKMSIEIESTGYVEGNLKAKETSYSKA
                     IRNDAILGIAPELTCGNSCNISKVVLKFNIADESVDNELNLFPDEPDLQGLKRLTIFKY
                     FEDMNMLLPIETKYDLENNTIYTEVDELGTYCIMDMEKWLANLGIGINEAEPMLMSFEA
                     EAVEDIAAEFNEESTRVEFSEETLAEINDEEDTLTEETFAPAMFAAAQTRGAVTVQTPV
                     DIAFLIQTSGQLEDTFNSQCEMIGNLMDSLIAQYGNGNVRFCLITYNLNGAQALKFTSD
                     GNIWFTNSVAVKMALSAQQYVYTSGYTDRGNAFKLLQNNVIFKETSAKFIFQVMNGSTN
                     VGSMYFDQINTCAKLGINYSELMPAGYSYIDPSYGQQVDNAIKSTGGLNLTYGTNSESS
                     VYNHIVGNVAPPHVEFKAVLPTGWETINLVNVLDPNNGAKSDNDDLTDWEEVDTESGLI
                     TWDNDGNIQLPTFEQCLNKVHDQGFSYVLNEYSDSIPSYMHRYFYGVEILPIKSNPCEE
                     DSDGDGLNDGYDPNSLSANNYSSQMIALDNTETVTIIQKCLEYLGYLDMQNQAYGTFGG
                     LSIAATQLFQLNHRTFSDGISFKKDSNDSYFIDLNTYYAILLEAKNNGFTDLVEDIVWF
                     NENYTPKTMPLEEFNASLNPNNPVFISSVKRSDFDKDNVYNDKVDIYVYDYTPILNGIL
                     RYGAQEFHFHYYSCNPSPVESLNYPCQKYDNTSNKCARLTGDYSWMISQVKNNAPYDVK
                     TSGSWNNFMKTVNANIRFSTSSFPFLYSDIIINAEIFGNILFGYAGHAGGFTKKELESG
                     GSLYSFVTTGEFDNTEDSTYVRYGYDLYNNVIKDYDYIHISQ"
     PFAM_domain     complement(12219..12527)
                     /aSDomain="Ntox44"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF15607.8"
                     /description="Bacterial toxin 44"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_564_0017"
                     /evalue="2.30E-14"
                     /label="ctg2_564"
                     /locus_tag="ctg2_564"
                     /protein_end="1314"
                     /protein_start="1211"
                     /score="53.7"
                     /tool="antismash"
                     /translation="MISQVKNNAPYDVKTSGSWNNFMKTVNANIRFSTSSFPFLYSDII
                     INAEIFGNILFGYAGHAGGFTKKELESGGSLYSFVTTGEFDNTEDSTYVRYGYDLYNN"
     PFAM_domain     complement(14787..14852)
                     /aSDomain="TSP3_bac"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18884.2"
                     /description="Bacterial TSP3 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_564_0016"
                     /evalue="9.00E-03"
                     /label="ctg2_564"
                     /locus_tag="ctg2_564"
                     /protein_end="458"
                     /protein_start="436"
                     /score="15.9"
                     /tool="antismash"
                     /translation="DTDGDGLKDGDEPYIGLDPTNP"
     PFAM_domain     complement(14853..14921)
                     /aSDomain="TSP3_bac"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18884.2"
                     /description="Bacterial TSP3 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_564_0015"
                     /evalue="1.30E-08"
                     /label="ctg2_564"
                     /locus_tag="ctg2_564"
                     /protein_end="436"
                     /protein_start="413"
                     /score="34.6"
                     /tool="antismash"
                     /translation="DTDNDGLSDYDEINIYGTDPLVP"
     PFAM_domain     complement(14931..14987)
                     /aSDomain="TSP3_bac"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18884.2"
                     /description="Bacterial TSP3 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_564_0014"
                     /evalue="1.70E-03"
                     /label="ctg2_564"
                     /locus_tag="ctg2_564"
                     /protein_end="410"
                     /protein_start="391"
                     /score="18.2"
                     /tool="antismash"
                     /translation="DSDSDGLTNAQEIELGTDP"
     PFAM_domain     complement(15027..15092)
                     /aSDomain="TSP3_bac"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18884.2"
                     /description="Bacterial TSP3 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_564_0013"
                     /evalue="5.60E-08"
                     /label="ctg2_564"
                     /locus_tag="ctg2_564"
                     /protein_end="378"
                     /protein_start="356"
                     /score="32.5"
                     /tool="antismash"
                     /translation="DTDGDGLTDYQEVYITGTDPTK"
     CDS             complement(16219..16374)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_565"
                     /sec_met_domain="TIGR04223 (E-value: 8.7e-15, bitscore:
                     49.8, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAIKKLMLKYGSSLAALALMIGVSSSSQACWWWYNQPKEPEGMK
                     KFVKED"
     aSDomain        complement(16237..16344)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg2_565_0002"
                     /evalue="6.00E-14"
                     /identifier="TIGR04223"
                     /label="ctg2_565"
                     /locus_tag="ctg2_565"
                     /protein_end="46"
                     /protein_start="10"
                     /score="49.8"
                     /tool="antismash"
                     /translation="YGSSLAALALMIGVSSSSQACWWWYNQPKEPEGMKK"
     CDS             complement(16686..17963)
                     /locus_tag="ctg2_566"
                     /transl_table=11
                     /translation="MSISEVIIESLNCLAESMVIVFYLYNMMKEDYRFRKKSLVPAVIL
                     CFISLDSVTLFLEYPWVHLIATFILMMAISSIMFECKFGTKIFCSLIFLIVILASESLP
                     MGILYMLNFGSPLEQLTSGAGRYIGMFCSKLFCFWFSVYIIEYSKNKQKDIPIKNWLSI
                     ILIPILSVFILNGIFVSYGLNHRQTINYLITVIGLLALNLFVFNFFDTYANQLKMKVME
                     QRLKSEEENYMLIENKYNEIRQLKHDINNQISVAKSMFSDGNPKEAIKHLDKLADSLSD
                     AGRICYTGISAVDAIINMKWQEALNKNIQFTTKINVFESVPIDNMLLCRILSNLFDNAI
                     EGAERCSYVNKYIYISLIQIDNKLRICVMNSSDEVDTQNLKSSKSGNGLHGIGVSSIKK
                     AVTQLNGVTSFEWENGIFTADILIEY"
     PFAM_domain     complement(16695..16991)
                     /aSDomain="HATPase_c_5"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF14501.8"
                     /description="GHKL domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_566_0018"
                     /evalue="1.60E-20"
                     /label="ctg2_566"
                     /locus_tag="ctg2_566"
                     /protein_end="423"
                     /protein_start="324"
                     /score="73.0"
                     /tool="antismash"
                     /translation="NMLLCRILSNLFDNAIEGAERCSYVNKYIYISLIQIDNKLRICVM
                     NSSDEVDTQNLKSSKSGNGLHGIGVSSIKKAVTQLNGVTSFEWENGIFTADILI"
     CDS             complement(17963..18670)
                     /locus_tag="ctg2_567"
                     /transl_table=11
                     /translation="MRIAICDDEKSYIEKIKKDIKSFQTHENEFEFSEFESGEEFIAEF
                     SNDKYDLLILDIEMKDLNGLQTAEFIRQLDKNVILIFMTGYDKFVYQGYEVKAFRYILK
                     NQPEPIYFKQLSDTIQEYYRNKKYIKVIDDGIEKELLTVDILYIEVYSHQIVIHTFNKE
                     YYQKGKLSDYEKMLEECLFVRSDKSVLINVTNIDYIKKNQVFMKNGKILYVSRNHLEKI
                     TRAFLKFSRNRWG"
     PFAM_domain     complement(17999..18247)
                     /aSDomain="LytTR"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04397.17"
                     /description="LytTr DNA-binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_567_0020"
                     /evalue="1.20E-15"
                     /label="ctg2_567"
                     /locus_tag="ctg2_567"
                     /protein_end="224"
                     /protein_start="141"
                     /score="57.6"
                     /tool="antismash"
                     /translation="TVDILYIEVYSHQIVIHTFNKEYYQKGKLSDYEKMLEECLFVRSD
                     KSVLINVTNIDYIKKNQVFMKNGKILYVSRNHLEKITR"
     PFAM_domain     complement(18353..18664)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_567_0019"
                     /evalue="5.10E-16"
                     /label="ctg2_567"
                     /locus_tag="ctg2_567"
                     /protein_end="106"
                     /protein_start="2"
                     /score="58.9"
                     /tool="antismash"
                     /translation="IAICDDEKSYIEKIKKDIKSFQTHENEFEFSEFESGEEFIAEFSN
                     DKYDLLILDIEMKDLNGLQTAEFIRQLDKNVILIFMTGYDKFVYQGYEVKAFRYILKNQ
                     "
     CDS             complement(18870..21611)
                     /gene_functions="other (smcogs) SMCOG1295:Sel1 domain
                     protein repeat-containing protein (Score: 96.9; E-value:
                     2.8e-29)"
                     /gene_kind="other"
                     /locus_tag="ctg2_568"
                     /transl_table=11
                     /translation="MSQLIVTSRYLKSGNQKNKTKRRNYTKYIATRETVEIRSQKFVDR
                     NANATKNQEQLINDLINDFPESKRYLEYEDYEREPTIENAGELISTIVERNADVVGNRQ
                     NFVGYMAMRPGVEKRGSHGLFNEKNEPIILNQAANEIAEHKGNVWSHVVSLRREDAVRL
                     GFDNSDAWRELVKRHISDIAKAQNIPLCNLKWYAAYHDTTHHPHIHLLVYSTNPKQGFL
                     TKAGIDKVRSVFANDIFHDDLQSIYQEQTVSRDELKAVSKNEFESIVNMIASNDHTDPQ
                     LEELIRKLYIQLQNVKGKKVYGYLPMEIKETVNKIFSELAKDENIQQLYEKWCGLERLK
                     YKTYTQKETELPKLADNKVFQPVRNMIIRTVLNMKPFDANTEIEGSEPNDEYFDNTPQS
                     MSPLFDEAEPLAETETDESAAAIKYYIKWNDQYKKACKLIYGKDAKLNDFKKAEQLLLS
                     ESQRGNVLAVYDLGKLYSTDKLGERNEETSIAKYTRALQGFLQIEPNSKKIKPYIQYRI
                     GKMFCYGLGTEQDYEKAFEWFERSAKQKNKFAQFSLANLYYYGSGVEKDLSQAFLWYQR
                     SSSQGQPYAAYSIAQMYRYGEYVTKDNDTAQRYYKQALSGFLKIENDDMANDDLFYKLG
                     QMFKFGLGTDSDVTKAIEYFRRSAEMNNKNGLFEYGKALLIGEHIPQDTDSALKILEKA
                     VKLKNSNAKRFLALEYISGEHLEQDFEKGIALLTECADSGDVIASYRLGKIYLQGEIMP
                     QNLDKAEKYLLLAEDSEYTQYALAKLYLQEEKYDIQKAVNYFENCAAKNHWASYQLGRI
                     YLFGAAELTKDKEQAIEWFTKSANDGNEYAQAMLDNISKFENDLLANTIFSLFVSLSRC
                     IQDSYDNDHKVLQSRVDRKLMRVIRKKKMELGEKEENHMDIQ"
     PFAM_domain     complement(19095..19199)
                     /aSDomain="Sel1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08238.14"
                     /description="Sel1 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_568_0026"
                     /evalue="6.50E-06"
                     /label="ctg2_568"
                     /locus_tag="ctg2_568"
                     /protein_end="839"
                     /protein_start="804"
                     /score="26.8"
                     /tool="antismash"
                     /translation="ASYQLGRIYLFGAAELTKDKEQAIEWFTKSANDGN"
     PFAM_domain     complement(19314..19400)
                     /aSDomain="Sel1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08238.14"
                     /description="Sel1 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_568_0025"
                     /evalue="8.10E-03"
                     /label="ctg2_568"
                     /locus_tag="ctg2_568"
                     /protein_end="766"
                     /protein_start="737"
                     /score="16.9"
                     /tool="antismash"
                     /translation="ASYRLGKIYLQGEIMPQNLDKAEKYLLLA"
     PFAM_domain     complement(19623..19718)
                     /aSDomain="Sel1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08238.14"
                     /description="Sel1 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_568_0024"
                     /evalue="3.30E-06"
                     /label="ctg2_568"
                     /locus_tag="ctg2_568"
                     /protein_end="663"
                     /protein_start="631"
                     /score="27.7"
                     /tool="antismash"
                     /translation="YKLGQMFKFGLGTDSDVTKAIEYFRRSAEMNN"
     PFAM_domain     complement(19869..19967)
                     /aSDomain="Sel1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08238.14"
                     /description="Sel1 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_568_0023"
                     /evalue="7.40E-07"
                     /label="ctg2_568"
                     /locus_tag="ctg2_568"
                     /protein_end="581"
                     /protein_start="548"
                     /score="29.8"
                     /tool="antismash"
                     /translation="AQFSLANLYYYGSGVEKDLSQAFLWYQRSSSQG"
     PFAM_domain     complement(19977..20072)
                     /aSDomain="Sel1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08238.14"
                     /description="Sel1 repeat"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_568_0022"
                     /evalue="3.60E-09"
                     /label="ctg2_568"
                     /locus_tag="ctg2_568"
                     /protein_end="545"
                     /protein_start="513"
                     /score="37.1"
                     /tool="antismash"
                     /translation="QYRIGKMFCYGLGTEQDYEKAFEWFERSAKQK"
     PFAM_domain     complement(20457..21608)
                     /aSDomain="MobL"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF18555.3"
                     /description="MobL relaxases"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_568_0021"
                     /evalue="4.10E-31"
                     /label="ctg2_568"
                     /locus_tag="ctg2_568"
                     /protein_end="385"
                     /protein_start="1"
                     /score="108.4"
                     /tool="antismash"
                     /translation="SQLIVTSRYLKSGNQKNKTKRRNYTKYIATRETVEIRSQKFVDRN
                     ANATKNQEQLINDLINDFPESKRYLEYEDYEREPTIENAGELISTIVERNADVVGNRQN
                     FVGYMAMRPGVEKRGSHGLFNEKNEPIILNQAANEIAEHKGNVWSHVVSLRREDAVRLG
                     FDNSDAWRELVKRHISDIAKAQNIPLCNLKWYAAYHDTTHHPHIHLLVYSTNPKQGFLT
                     KAGIDKVRSVFANDIFHDDLQSIYQEQTVSRDELKAVSKNEFESIVNMIASNDHTDPQL
                     EELIRKLYIQLQNVKGKKVYGYLPMEIKETVNKIFSELAKDENIQQLYEKWCGLERLKY
                     KTYTQKETELPKLADNKVFQPVRNMIIRTVLNMKPFDANTEIEG"
     CDS             complement(21725..22633)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 177.5; E-value: 8.1e-54)"
                     /gene_kind="other"
                     /locus_tag="ctg2_569"
                     /transl_table=11
                     /translation="MFEYRPFVDQFLDYCRYHKKLSEKTVRAYKIDLSQYALFSDTLSK
                     QALWDYIECLNKKYKPKTVKRKLATLKAFIHFLLLQDYIDFNPFDKLETSIREPVLLPK
                     TIPLDVIAKIISFSYQQIGSAQSAYQMKCAVRNAAVIELLFATGARIAEICTLKPENVD
                     LLGRSVKFYGKGSKERLIPVENMAVLSILKRYRLLFEDNISVSGYFFVNKLGRRMTEQS
                     VRNMLSSYCNQCGVEMHITPHMFRHSFATLLLEEDVDIRYIQRMLGHSSITTTQIYTHV
                     TSSKQKEILKTKHPRNKMDFQ"
     PFAM_domain     complement(21788..22240)
                     /aSDomain="Phage_integrase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00589.24"
                     /description="Phage integrase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_569_0028"
                     /evalue="6.50E-40"
                     /label="ctg2_569"
                     /locus_tag="ctg2_569"
                     /protein_end="282"
                     /protein_start="131"
                     /score="136.8"
                     /tool="antismash"
                     /translation="KCAVRNAAVIELLFATGARIAEICTLKPENVDLLGRSVKFYGKGS
                     KERLIPVENMAVLSILKRYRLLFEDNISVSGYFFVNKLGRRMTEQSVRNMLSSYCNQCG
                     VEMHITPHMFRHSFATLLLEEDVDIRYIQRMLGHSSITTTQIYTHVT"
     PFAM_domain     complement(22397..22612)
                     /aSDomain="Phage_int_SAM_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02899.19"
                     /description="Phage integrase, N-terminal SAM-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_569_0027"
                     /evalue="1.50E-08"
                     /label="ctg2_569"
                     /locus_tag="ctg2_569"
                     /protein_end="79"
                     /protein_start="7"
                     /score="34.9"
                     /tool="antismash"
                     /translation="VDQFLDYCRYHKKLSEKTVRAYKIDLSQYALFSDTLSKQALWDYI
                     ECLNKKYKPKTVKRKLATLKAFIHFLL"
     CDS             22893..25859
                     /locus_tag="ctg2_570"
                     /transl_table=11
                     /translation="MSDFQKNSSNFEDLCLKIVKKLLGNSLNKIKKTQPSKDGGYDIDA
                     TIKYKNKQYSVLFECKLRGKNVNLRDIAANVIIAYNNCTDSLVFMINQYFTPQLEEQLL
                     RFRDSSQLNIKVLIGSDIENVIQNNNIPVSTELAELLKDNNKSRKNKHISSLVLNTDSE
                     NICKQIIEKPQVNSDNKESDFIAQVYSNELNRAVSLLKNNKSFIVQGYIGMGKSAFVRK
                     ILNTVDCMCIRLNADVCQNQEQVILHLIRNIWGLPDNSFLGMFEEDDIDYITRTINDNY
                     SMETCKFIKYILNQTSLSIKIEANYILCEYLVCIMKRHYPKTKYVVYFDNFHSANQEVN
                     DFFVYLINLFSEKDIPCIIEYDLSEYDLQKQNLMAYNKIINKYAIIDIATLTEEQAKTW
                     FIQELNITEKTANQIVKRVGTRFYNIKFISQNLKRRMHTPNFEKAMELLDMLTPNDLSD
                     ITSQIINSCKKKDKKLFYLLKMLNCRIPIDLCSYLNLSYSSLLKEGIIVREDRYIFVSN
                     EFVKQAVMKETSDLVNEQNISELILDFCTHNPGKYKDVIIYGLFYAGKLEEATKEIDLL
                     IKELGQKRNFTLMLEFIELAITISENNKNAHALSNYLIKKLEVYAIIKSLMLDKARLTL
                     DHLQTLVNSGQLDLLDESYSELAICYFKGTIALKDYAFSDDLLNEHYKYFKNCIDGLMK
                     DNPDDYLGKVCSNYAIYIKETKGNSAALEVFGAALKALPNSQTLYIEHLSHLACISLSY
                     EPQKSYEYYSKIIEKVNNSQTFYCFPFHEYGDKAMCKVLLKEVNKAVSHSDLGIKYAES
                     HGVFDEVGRILNIKGCAFLLADKVSEAVKCFKEATEIMEYSGYKHYSWRSKLNYVNYFI
                     TSGNKEELIKMLYDAYSIFKSGLITKVQNLIESCDDFISSREYLVLLVVGKCSQLLFDT
                     KASQRADYISAEKIADEFRFPDKIKKHYLKTINQLINHHEQLELKSIYIYNGDIFIIG"
     PFAM_domain     22917..23207
                     /aSDomain="Mrr_cat"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04471.14"
                     /description="Restriction endonuclease"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg2_570_0029"
                     /evalue="4.90E-06"
                     /label="ctg2_570"
                     /locus_tag="ctg2_570"
                     /protein_end="105"
                     /protein_start="8"
                     /score="26.7"
                     /tool="antismash"
                     /translation="SNFEDLCLKIVKKLLGNSLNKIKKTQPSKDGGYDIDATIKYKNKQ
                     YSVLFECKLRGKNVNLRDIAANVIIAYNNCTDSLVFMINQYFTPQLEEQLLR"
ORIGIN
        1 gataggtctt ctgaaattgt gcaaagtgaa tttgcttttc tcactcgctt ttcatttgct
       61 tgtctgaaga tatcctcatc gatcaactgc ggatatttgt cagttcccag atacttttca
      121 ttttctatga tccgcttgac catgtttttg ttccaatgat cggaatcact gttgtatcgg
      181 attttttcgg actccataag ctttgcaatc tgcaaaagac ttttgccatt aagatattcg
      241 ctgaaaattg ttgcaactgc gtaaacctct ttaggctcgg tggttatttc gccgtttttc
      301 atgcagtagc cgaatgggat tactctgttt ttgagcatat taatttcacc tccgaaaaca
      361 acaataccat aaagcctttg aaatagctat atccaaaggc aataaattta tgatgtagaa
      421 attgtctatt ttatcttctc attaaatttt aaaccgccga ttaagtgaaa ttccagctca
      481 tgctgattta tcacaacgat cttttcaact atgccctcaa acgtcgactc gtcaaattct
      541 gttattggat tactttgttt ttcaaaaaag tctatcagca tttctatttg gtcaattgtt
      601 tcgtcctcgt catcggaacg ggtaagcttt ttcagttcgg cctgcagctt attgattttt
      661 gctgtaagct ccgtagtctg ctcaatgtat tttacctcgt ccagaaaccc tttggttttc
      721 agtcttgcaa ggacgtgtgt ctgttcacga agcttggcgg tttgcttgtg aatgtccatt
      781 acctgagttt tactgctgag ttttcggagt ttcagatcat gcagcgctgt ttgaaaaggt
      841 acaaggattt gtttgtaatt gtaccaaagt ttattgcata atctgataaa agcagagtgg
      901 atattatctt gatttattgg ttttaccgag cacttttcta tttcatcggt atgaagtctg
      961 caaacccaat atatttttcc tctgcaattt ttcatacgga aagtagttcc gcattcaccg
     1021 catttgattt tcttggacag tatattaccg cggctttcat tccgcttatt ttcaccccga
     1081 agacgtatta attcctgcac tctgtcaaat acatcttttg aaatgacggc ttcatgacat
     1141 ccggtgtaat aatactgagg taattctcct ctgttcggca aatttttacg aggcaaaacg
     1201 gttgttgtaa accgtttctg aaacagctga tctccgatgt atttttcatt tttaagcata
     1261 actctcacgg taggtcctgt ccagtggcat gatctacctc tttttccaat tcccatttca
     1321 tttaacatct gagcgatttt ttcacttccg tatccgttca gataccaatc aaatattttt
     1381 ctgactatcc gggcttcatc ctgatttaag atcaattcac cgttgacaag ttcatatcca
     1441 aacaccgagt tgcacatttt cattgtgccg ttttccattc gcttttttat gctccaccgc
     1501 atattctgcg aaatcgaagt cgattcctcc tgagccagac cgcccattat tgttatcatc
     1561 atttcatcgg tcatattagc tgtatcgata ttctctttct cgaaaaacac cgtaatacca
     1621 agagatttca gttcacgaac gtttttcaga caatctttag tgtttcgggc aaatcggctg
     1681 atagacttgg tgtatatcct gtctatcctc cctttgcggc aatcttttat cattctctga
     1741 aactcgtcac gcttgtcctc acgggtacct gttataccct cgtcggcgta cagatcgatc
     1801 agttcttccg tttcggagtt ctcaaaaaac tgactgtagt atcttgtctg agccataaag
     1861 gaattaagct gatcttcgct gtctgaactt actctgcaat atgcggcaca acggatcttc
     1921 gtattttgtt cttctgtgat tgtcggctgt attaccgtta ctgtcggcat ttcctcacac
     1981 tcctttcaac caacaaggat accacaaatt ttttaggaat ggtatcatca aactcaatga
     2041 atttctttgt ccgaatctgt gcagttttca tgtttgtctg cttgccctgc cgctgtgcaa
     2101 agacacattg cggtcatgcc gataaaagct ccgacaaaca agccaataaa aaatcctaac
     2161 atcttaatac ctccttaagc tgcatctttt gacgatacaa attctttgta aatatcttct
     2221 gtgtttctgc ggttgaaatt ctgtttttcg gtagtttcaa gaatttcatc aagcttatcg
     2281 gcaaacattc ttgccataaa atcgccgtat tctgcttgtc cgaatttagt catcaaaatc
     2341 cactcctata cttattttca ttgcctcatc gattttattt attatcccgc tgtccaatga
     2401 gcctatatag ctccgaagtc tgctgcggtc tattgtccta atctgctcgg caagaatgac
     2461 cgaatcttta ggcagtattt ttgaatttct tatgcagata tgcgtaggaa gcttgttttt
     2521 cttaactgtt gacagcggca gaaccacaag cgtgggacta tgcctgtttc cgatattgtt
     2581 ctgaaccacc agcacgggac gaacaccgcc ttgctcagaa ccgactacgg gatctaaatc
     2641 tgcgtaaaaa atatctcctc gtttgatcag catttcattt cgccaccttt tgcggaactt
     2701 caaagccttt tttgttccta acgcagttat gaaacgggca gaaaagaaca tcagcattct
     2761 tgtcatacca cacacaacca taacatgggt gtttgtttga taacctgact gttggtacag
     2821 gaatgtttac tccaaattta taaaaatctg atttctcagg aatatcgtta tctttcatat
     2881 atcagcctcc tgacctttta tttttatatg taacaggcgg tctgcaaaag aatgcaaacc
     2941 gccttattaa ttcgttttgc cttcgtctga ttcgtaagtt tcagacgaat ttccgtgata
     3001 tttatcctag atacccgtca cggcggaaca tcgggaacga tgaacagctt attcatctca
     3061 tgagcctctc actccactat ggttctcata gagccgcccc cattgcttga gtctgtggct
     3121 gggcggaagt atcattatcc tcctgcgttt catcgcctgc tttggttgct gtccaaaggt
     3181 ctgaacgtca tattgatcgc tcgctcaact gaggtcgtgg cgtatggttc atgcggctgc
     3241 cgagatttta taccggccgc aggattaacg ttttcccgat gctgttattc tgttgtcaag
     3301 attctcaggg atttggatcg ctcctttttc cctttcacct tgtagccgat gagaacaccc
     3361 tttttatgcg tttgaaaatt gacttcttaa aatttcagca attttatcaa ttacgcggga
     3421 tatattcgac tgatttctta gtaaaattga cgaaatttca ttttgagtgt acccgtcaaa
     3481 tatgtacatt gtaaaagctt cacgccagat ttccggcaag gacatgatct gcgaatacac
     3541 ttccatgtcc tcaatctcat cgatccagcc ataacgattg tttgtcgaat aatcatcata
     3601 aaccgtcagc gttctgctgt ttgaattatc aaacagtcca actgtttttt ctctgtaacg
     3661 ccgattggag ttgaaaacct cacggtcaaa ctcataaatt tccgctatct gtttctcagt
     3721 catccctgct tttctgtact cctcagcggt tttctgccac tgttctttaa atttcttttc
     3781 ctccaagcca tgattatagc tcatattttt acctccgttt tgatttttcg ttctgaatca
     3841 aaacgaaggc ttatgggtat ttggcaataa aacattgcca ataattaaaa atgggcataa
     3901 aaaagacctt tctgctttta aaacaaaaag gtctgttaag aaaaaggagt ataactttcg
     3961 gctttaaaag cttttgttat actcctcatg ttatattatt ccaataagtt agccatcgtt
     4021 aaaatcataa tttaaattat aactaaactc atattcccca taattggaag aataaattct
     4081 tatatagtac ctaccaggtt ctaaatcgta ctcaatagtt tctatttcac cacgacaggt
     4141 agtataagat agagtttgct ctccatctgt accaatcaat cttatttcgt attgaaatgg
     4201 ctctggtgaa tttgtgttta ttatgatatg cttcctttca ttaatattaa acatatacca
     4261 atcatattga tcgtattctt ttttatcgtt tacaaagcct atagaaccat taattgtttc
     4321 atcagctttt gtttcaattg aattttgata tgtattatta ggttcactgt ccaaattttt
     4381 tatttcaaca gaattcatct gcaattgata gccgccatag ttttccaaac actctatacg
     4441 aatatagtag gttcctgatt gtagcggaca aataagctta atttctttat tcttgccgta
     4501 atcgctatat atttctgttg cgccatcaga agcaatgaca aatatctttg cttttaaatc
     4561 tgaatccata gtaagattaa aggtatataa ttgaaaagaa ttcaaaatta gtttataaaa
     4621 atcatcagta tcggtttcgt taggctggtt acttttatat cctatatggc catttaaagt
     4681 attggattca atcagtttag cattttgata tggtgaattt atttcctcat ctttactata
     4741 tccgcttgta ctaaattgac tatttaaaga atatgtacct gattgctcat aggatatttt
     4801 tatataatat tcacccgctt ggataggcgt gttaagattt agtatgcgat cctgtccgca
     4861 atcataatta agtctatcat ttccattgat acatattaaa ttaatattgc aatacactcc
     4921 agcagaagca tttaacgtta atgataataa accgtcttcg gaaatattta taatatacca
     4981 aacacaatta tcattatcct ctgaatatgt aaaagttttt tcatatgttt cacctattgt
     5041 cagcgatata gcatcaatgt aagtattacc gcttttttct gtagggggtt cagttgtagt
     5101 ggtattatta gtagtagtgg tagtagtttt cgttgttgaa gcggtggtag tcttattagt
     5161 agtgcttgat gttgttacga cctcagaata tgatggttcg tcataatatt cttcagtatc
     5221 ttcatcaaat atcggagaag atatccacgg aaatataaat gttaaaatcg ttattactgt
     5281 tgtagcaaca ttggttatta ttctacccca tttccgtaaa tcttttgatg tttgaatcgt
     5341 ttggaattct ttttaataca aaatttacta taattgcaat aataattatt accactattc
     5401 ctgcaattcg tgccataatt tcttttaaca tatatatcac cacttttttg ttttattaca
     5461 ctctaacaat tgtatcatac cattttaaga caatatattc aacttcttta cccgaaataa
     5521 atttattcga cgtaaactgt aaggcttgtt cttgatttat taatattttc tttttgtaat
     5581 taaataatga aaattcgcag taatattctt agtttcaagt gagagaaaaa tgggactgtt
     5641 gagcacacgc tgcagcagtc ccatgattat gcatattaat atgatatttt taggtagtca
     5701 aaaatcatgc cgattgtaaa aaagatacca ctttccactc atcattaatt ttttcaaagt
     5761 atagtctatc aaggatggat ccgtctgtaa ctattttaca ttcaattcta ttgctgctcg
     5821 attgcataga acaatcctta gtaaaaaata caatagcctt atcttcacta cataggcatt
     5881 gcacatccac gctgattaat tcaaaatcga acttatttcc tgtattattt ggattcagtc
     5941 ttttaaaaat atcattagaa acaatggttg tatattgatc attaaatcca ttattataat
     6001 aggaatccaa aatcatattt tttgctaatt cttctaaaag atttttttca tcgtcatcta
     6061 taaatatata taattttctt aagtccgata cttcaagata ttcagcatca gatatcgatg
     6121 ttgatgaacc atcatctaga ttaacgatac aagttaattt gattattaca cataccaata
     6181 agattataat aaaaatgcta gaggctacac aaattatgtt ttttctcttc atgctggaac
     6241 cctaccgttt aagcaaacaa tgatgacatt tgtataatct tcattttcgt caaatgtttc
     6301 tgatagtttc ttgttccatc ttggtttggt atgaccagca taaagaatct catctttctg
     6361 cacactggat attattgctg tatgtgttgg tcctttttct ttacaaaagt aaatcaaatc
     6421 tcccatacgt atatcatatt tggatatagc ttcctcaata gattcatctc tacctataga
     6481 tacctcatac atcgcgtatt cttcagaacg aaaatagtta taattatcaa ctacaacaga
     6541 ccatgattta gtccagccat aatcccatgt tcctgtatga gaaaataatc catgaatatg
     6601 cgatgctaag ccttcagctt tcccaaaata ccaatcatta ttcattttaa atccacctgc
     6661 acataaacat tgagaagcaa aattagtaca atcagtcatt ttatcgctta attctgaaaa
     6721 gttaggatac tcactataat tgtacttttc accaactgtg tcataatctc cggaccactt
     6781 cttcatgtaa tcatatacgg catttctatc atatgattca tttacaatcc aaggttctaa
     6841 gtcatactta tcataaatat catctccatc agaatcctta gaaaatggtg atgatacata
     6901 tagtattaat ggatcggtat aacctgtata tatcacttct tcgtgatcta aaagaccatc
     6961 accatctgta tctgcatcgc aaggattgga atgaatcggc aatatttcag cgtttaaaaa
     7021 aactttccat attgtacttg gagcatattt taaatatgtc tctaaaacat ttctaacata
     7081 aaatttattg cttgctttct ctaagcaatc cttaaaagtt ggcaactgaa tattgccatc
     7141 gttatcccat gtaataagcc cactttcagt atcaacttct tgccagtctg ttaaatcatc
     7201 attatctgag tttgctccgt tattagggtc taaaatattt tttagggtta tcgtttccca
     7261 atttgttggc agtacggctt taaattcaac atgaggtgga gcaacattac ccacaatatg
     7321 attataaaca ctactctctg aatttgtacc atatgttaga ttaagtccgc cagtactctt
     7381 tatcgcatta tctacctgct gtccataaga aggatcaatg taactgtaac ctgccggcat
     7441 taactcggaa taatttatgc ctaatttcgc acatgtattt atttgatcaa aatacattga
     7501 accaacattc gtagaaccat tcattacctg aaaaataaat tttgccgatg tttctttaaa
     7561 aataacatta ttttgtaata gtttaaacgc attacctcta tcagtataac ctgaagtgta
     7621 cacatattgc tgtgcgctaa gagccatttt aacagccaca ctgttggtaa accatatatt
     7681 tccgtcagat gtaaatttca gagcttgtgc tccattcaaa ttataagtaa taagacagaa
     7741 acgtacatta ccattcccgt attgagcaat tagggaatcc atcaaattac caatcatttc
     7801 gcattgtgaa ttaaatgtat cctcaagctg accggaagtc tgaataagga acgcaatatc
     7861 aacgggtgtc tgaacggtaa cagcgcctct ggtctgagca gcagcaaaca ttgcaggagc
     7921 aaaagtttct tcagtaagag tatcttcctc gtcatttatt tcagcgagtg tttcttcaga
     7981 aaattctaca cgtgtagact cttcattgaa ttcagcagct atatcttcta ccgcttcagc
     8041 ctcaaaggac atcaacatag gttcagcttc gttaatgccg attccaaggt tggcaagcca
     8101 tttctccatg tccattatac agtatgtgcc aagttcgtca acctccgtgt aaattgtatt
     8161 gttttcaagg tcatactttg tttcaatggg cagaagcata ttcatatctt caaagtattt
     8221 gaagattgta agacgtttta atccttgtaa atccggctca tcagggaata gattaagttc
     8281 attgtctacg gattcatcag ctatattaaa ttttaacaca accttgctga tattgcaaga
     8341 gttgccacaa gttaactccg gtgcaatgcc aagaatggcg tcatttctta ttgcttttga
     8401 gtagcttgtt tcctttgctt ttaaattacc ctcaacataa cctgtcgatt caatttcaat
     8461 agacattttg taaggactat cgtcagtatt gatctcccta agagcctcgc tgttctcggc
     8521 aatagtctga ttgcttacat attccgcatc gggaacgtca aatgtttcag gatttgtcgg
     8581 gtcaagtcca atatacggct catcgccatc ttttaagcca tcaccgtctg tgtccggaac
     8641 gagaggatca gttccgtaaa tattaatttc atcgtaatct gaaagtccgt cattgtccgt
     8701 atcatcattt cttggatcag ttccaagctc tatttcctgg gcattggtca atccgtcact
     8761 gtcagaatct gcatcagcgt ccgaaacacc ctcggttact gaatcgtact ttgtaggatc
     8821 tgttcctgtt atgtatactt cctgataatc ggtcagtcca tcgccatcag tatcgggatt
     8881 attcaaatct gtaccgatca tattctcata aatgtccgga agcccgtcac cgtcgctgtc
     8941 aagaaaatca acagaatagc catcttctgt ttttgttaca acaaaaggta ctgattcaat
     9001 tctctcgccg taattggtga taagggaaac cttgaagtat tttgtttcaa agtcatcggt
     9061 gatcgggtac tgataggtag ttgcatccga aacgacagct acggatgtat agttgacatt
     9121 atcatctgaa ctccatatct catagctgct gtttttgtaa ttggtgtacc actccatatc
     9181 tatgctgttc gcatcgctgt tatactctcc gaaagcataa agctcaacct caatgtcaga
     9241 ttctgttccg acaagttcag ccatactgtt gctgtaatta gcattaatgc taggacagtc
     9301 gatggtgata gtttgtccga taatgataac attgttgagg ttaaggttat ctgtatcgat
     9361 gttgatatct ccgtaaggag cataaatcaa gccgctgaaa ttaacgttgc ttgtttcgat
     9421 attgatatct cctgtttcgg agcaaataac agaattgttc gtattcttaa cctctccatt
     9481 gatggtaaca tcttcaacag ctttaattcc tgaattgaga ttaatatttc ccgtaagttc
     9541 tagagtgccg ttaacatcca tgggattatt aatgttgatg ttcaggtcct caaagctgta
     9601 atcgtcagca tatgtttcaa cgttatcgcc actgaaatac gagtagttca gttttttgag
     9661 aatgtagatc atttcttcgt cagcattctc agttttcgta ccgttgacat tcatatttcc
     9721 gcttgaaaca attgtgccgt ttgtcgctat atttccattc acacagaaat tattagcatt
     9781 aatggtgata gctccttctg tatcagaagc ggcaaacatt gtatagggat acttttctgc
     9841 tgcatcctct gcaactgcag gcaaactcgg caaaagagtt gctgccatag ctacactcat
     9901 tatgccggaa agtattcgtt tgaagttgtt ttttccttgc ataacttctc ctccgttccg
     9961 cagtatcgga gcgccgaagc gctccattac cgctttttta ttagtcttct tttacaaatt
    10021 tcttcatacc ttcaggctct tttggctgat tgtaccacca ccagcaagcc tgagaactgg
    10081 aactgacgcc tatcatcagt gcaagtgccg ccaatgatga accatatttc aacatgagct
    10141 ttttaattgc cttcatattt ttcaccgcct ttccttttta aaaaatttat gcaaattctc
    10201 aggctctttc ggctgacaat atgttatact gcaggcttgt cccgttacta ttgccgttat
    10261 gccgtagacc gcactgaaaa tcaacgttat gaatatgatt ttatgagtag ttttattttt
    10321 tctgcaacca ttgcacaagt taatgtaaat attcctgtta ctgcataaaa gcatacttct
    10381 gttttaacaa aatagaaaat aatgcagaat attgtccata taaaaaatga aatcaaagat
    10441 ttttttctta acttcatctt ctttttctct gatataggtt tgtttggatg ttcaaccggt
    10501 gcaaatttat ataaaattaa tactgataaa acccatagaa tcggagataa aaaccttatc
    10561 gtagctgtac taaaagtctt tattattaaa ataaaagcag aaagtacaca cacaagtgtc
    10621 agcatacatc cccaatgcgt atcagcatgg tatcctccgg catacattct tatagttaca
    10681 aacgctgtca aattaataac acaaggaata aattcattgg aaattaaagc aataataata
    10741 gctataatta agttgaagat tgtagataac aataattcta ttccataagc ataaacttca
    10801 gaatcttcca cttctattat tttattgtcg acaaaaaaac acgccgtacc ttttgcgagt
    10861 tttgaaatca tttttcatca cctcgctttt agtatagcgt gtttaagtta tttttttcaa
    10921 tagttttacg tcaaatgaca tttcttgacg ttaaagctca tctattttta taatttgttc
    10981 atatatagat tctttctgat ttatttgatt tctaattcgc tggttaaata tttttatgaa
    11041 attttacaat tacctcatta ttgagttccg caaatttaat atatggagtg aaatcatcgt
    11101 aataatcaag acgttttttc caaatatatt cgattgatcc attgtcatta tgcaccaaat
    11161 acacatttaa tcttattgaa cctgataaac ctgcttcact gcaatttctt aatgaaatag
    11221 tatattttcc attttgggtt gtataactat tatattcttc gaattcatta aacttatacc
    11281 acatcgtttc cgaaaaatca accatccatc gcttaaaaag gaatatttgc ctttgtgtat
    11341 atgaaatccg caacggcatt gcaagccgac ttctgcttaa ctatagccgt cagagaagcg
    11401 gagaagccct tagagagctg ttctcaatga ttatgaggga aatacaatca ctctaaaaag
    11461 caggctccca aatcgttttt ttgagagcct gttaaacagt tagagtgtgc ctattgtgat
    11521 atgagatata gtggcgattt taacttgttt ggttttgaat ataattaagc aattattttt
    11581 tttaattgca ataataaatt actgaaatta tccgtttaaa acatctttag accatagata
    11641 ccaatttcct gaaaatggtt tgcttttgat tgtggaattg tcgatagcta aatctgaacc
    11701 atgtccatta tactcattat caatatacac gaggtaataa tttcgtatct tatcattctc
    11761 aatttttctg ttttttacta taaagtacat cagcatattt ccttgattat catagtttac
    11821 acgaataaag gaaaacacat tataagggct gtctttttgg tatttattcc gcatataagt
    11881 gaaatattta tcaaaagttt cttctccaca atcaatatat tcactatttt tccctaaaca
    11941 cttctcgatt atatggtcat cttgtgaata tataatcata gggattgaat catatttata
    12001 tttttcaaaa taatcaacaa tggattccat atattgtttg ttattcttat aacagttttt
    12061 aacatactct tgatgtactt tttccttgta aataaaacta attatgaaaa acaaagcagg
    12121 aattaatact atcagcacaa taatatattt tttttcatag taattacccc ggatatatct
    12181 tactgtgaaa tatgaatgta atcataatct ttaatcacat tattgtaaag atcatatccg
    12241 tatcttacgt atgttgaatc ctctgtatta tcaaattctc ccgttgtcac gaatgaatat
    12301 aagctaccac cactctctaa ttcttttttc gtaaagccac cagcatgtcc tgcatatccg
    12361 aagagaatgt ttccgaatat ctcagcattt ataattatgt cagaatataa aaatggaaat
    12421 gaactggtcg aaaaacgaat attcgcatta acagttttca tgaaattatt ccaacttccg
    12481 cttgttttta catcatatgg agcattattt ttcacttgac taatcatcca ggaataatct
    12541 cctgttaaac gagcacattt attggatgtg ttatcatatt tttgacaagg ataattaaga
    12601 ctttctacgg gtgaaggatt acacgaataa taatggaagt gaaattcctg tgctccatat
    12661 ctgagaattc catttaatat tggcgtataa tcatatacat aaatatccac cttatcgtta
    12721 tatacattat ccttatcaaa atcactccgt ttaacagatg atataaacac tggattatta
    12781 ggatttaaac ttgcattaaa ttcttccaac ggcattgtct ttggagtgta attttcatta
    12841 aaccatacta tgtcttcaac taaatctgtg aatccgttat tttttgcttc taataaaata
    12901 gcataatatg tattaagatc aataaaatat gaatcatttg aatctttttt aaacgaaata
    12961 ccatctgaaa atgtacgatg atttaattgg aaaagttgtg tagcagcaat tgacaaacca
    13021 ccaaaagtac cgtaagcctg attttgcata tcaagatatc ccaaatactc aaggcatttt
    13081 tgaataattg taacagtttc agtattgtca agagcaatca tctgtgaact ataattattt
    13141 gctgaaagtg aattaggatc gtaaccatca tttaatccat ccccatccga atcctcctca
    13201 cagggatttg acttaattgg aagaatctca acgccataaa aatatcgatg catataactt
    13261 ggaatcgaat cactgtattc attcaacaca taagaaaaac cctgatcatg aactttattc
    13321 aaacactgtt caaaggtagg caactgaata ttgccatcgt tatcccatgt aataagccca
    13381 ctttcagtgt caacttcttc ccagtcggtt aaatcatcat tatctgattt tgctccatta
    13441 ttaggatcta acacattgac taggttaata gtttcccaac ctgttggcaa tacggcttta
    13501 aattcaacat gaggtggagc aacattaccc acaatatgat tataaacact actctctgaa
    13561 tttgtaccat atgttagatt aagtccgcca gtactcttta tcgcattatc tacctgctgt
    13621 ccataagaag gatcaatgta actgtaacct gccggcatta actcggaata atttatgcct
    13681 aatttcgcac atgtatttat ttgatcaaaa tacattgaac caacattcgt agaaccattc
    13741 attacctgaa aaataaattt tgccgatgtt tctttaaaaa taacattatt ttgtaatagt
    13801 ttaaacgcat tacctctatc agtataacct gaagtgtaca catattgctg tgcgctaaga
    13861 gccattttaa cagccacact gttggtaaac catatatttc cgtcagatgt aaatttcaga
    13921 gcttgtgctc cattcaaatt ataagtaata agacagaaac gtacattacc attcccgtat
    13981 tgagcaatta gggaatccat caaattacca atcatttcgc attgtgaatt aaatgtatcc
    14041 tcaagctgac cggaagtctg aataaggaac gcaatatcaa cgggtgtctg aacggtaaca
    14101 gcgcctctgg tctgagcagc agcaaacatt gcaggagcaa aagtttcttc agtaagagta
    14161 tcttcctcgt catttatttc agcgagtgtt tcttcagaaa attctacacg tgtagactct
    14221 tcattgaatt cagcagctat atcttctacc gcttcagcct caaaggacat caacataggt
    14281 tcagcttcgt taatgccgat tccaaggttg gcaagccatt tctccatgtc cattatacag
    14341 tatgtgccaa gttcgtcaac ctccgtgtaa attgtattgt tttcaaggtc atactttgtt
    14401 tcaatgggca gaagcatatt catatcttca aagtatttga agattgtaag acgttttaat
    14461 ccttgtaaat ccggctcatc agggaataga ttaagttcat tgtctacgga ttcatcagct
    14521 atattaaatt ttaacacaac cttgctgata ttgcaagagt tgccacaagt taactccggt
    14581 gcaatgccaa gaatggcgtc atttcttatt gcttttgagt agcttgtttc ctttgctttt
    14641 aaattaccct caacataacc tgtcgattca atttcaatag acattttgta aggactatcg
    14701 tcagtattga tctccctaag agcctcgctg ttctcggcaa tagtctgatt gcttacatat
    14761 tccgcatcgg gaacgtcaaa tgtttcagga tttgtcgggt caagtccaat atacggctca
    14821 tcgccatctt ttaagccatc accgtctgtg tccggaacga gaggatcagt tccgtaaata
    14881 ttaatttcat cgtaatctga aagtccgtca ttgtccgtat catcatttct tggatcagtt
    14941 ccaagctcta tttcctgggc attggtcaat ccgtcactgt cagaatctgc atcagcgtcc
    15001 gaaacaccct cggttactga atcgtacttt gtaggatctg ttcctgttat gtatacttcc
    15061 tgataatcgg tcagtccatc gccatcagta tcgggattat tcaaatctgt accgatcata
    15121 ttctcataaa tgtccggaag cccgtcaccg tcgctgtcaa gaaaatcaac agaatagcca
    15181 tcttctgttt ttgttacaac aaaaggtact gattcaattc tctcgccgta attggtgata
    15241 agggaaacct tgaagtattt tgtttcaaag tcatcggtga tcgggtactg ataggtagtt
    15301 gcatccgaaa cgacagctac ggatgtatag ttgacattat catctgaact ccatatctca
    15361 tagctgctgt ttttgtaatt ggtgtaccac tccatatcta tgctgttcgc atcgctgtta
    15421 tactctccga aagcataaag ctcaacctca atgtcagatt ctgttccgac aagttcagcc
    15481 atactgttgc tgtaattagc attaatgcta ggacagtcga tggtgatagt ttgtccgata
    15541 atgataacat tgttgaggtt aaggttatct gtatcgatgt tgatatctcc gtaaggagca
    15601 taaatcaagc cgctgaaatt aacgttgctt gtttcgatat tgatatctcc tgtttcggag
    15661 caaataacag aattgttcgt attcttaacc tctccattga tggtaacatc ttcaacagct
    15721 ttaattcctg aattgagatt aatatttccc gtaagttcta gagtgccgtt aacatccatg
    15781 ggattattaa tgttgatgtt caggtcctca aagctgtaat cgtcagcata tgtttcaacg
    15841 ttatcgccac tgaaatacga gtagttcagt tttttgagaa tgtagatcat ttcttcgtca
    15901 gcattctcag ttttcgtacc gttgacattc atatttccgc ttgaaacaat tgtgccgttt
    15961 gtcgctatat ttccattcac acagaaatta ttagcattaa tggtgatagc tccttctgta
    16021 tcagaagcgg caaacattgt atagggatac ttttctgctg catcctctgc aactgcaggc
    16081 aaactcggca aaagagttgc tgccatagct acactcatta tgccggaaag tattcgtttg
    16141 aagttgtttt ttccttgcat aacttctcct ccgttccgca gtatcggagc gccgaagcgc
    16201 tccattaccg cttttttatt agtcttcttt tacaaatttc ttcatacctt caggctcttt
    16261 tggctgattg taccaccacc agcaagcctg agaactggaa ctgacgccta tcatcagtgc
    16321 aagtgccgcc aatgatgaac catatttcaa catgagcttt ttaattgcct tcatattttt
    16381 caccgccttt cctttttaaa aaatttatgc aaattctcag gctctttcgg ctgacaatat
    16441 gttatactgc aggcttgtcc tgttactaat gtcgttatgc cgtagattgc actgagaatt
    16501 aacgttataa taagtcctcg ttttgtttcc tgattcagtt tcttcatcga tcaattactc
    16561 tccaagataa aaaaatacgc tatactttta ctggatgttc ccagttttca gtatagcgta
    16621 tactatttat ctttttcaag gcttttgcgc caaagtactt tttatgacat taaatgtcac
    16681 cttcgttaat actctattaa tatatcagca gtaaatatac cattctccca ctcgaaagat
    16741 gtaaccccat taagctgagt cactgccttt tttatactgc ttacacctat accgtgtaat
    16801 ccgtttcccg atttactcga cttaaggttt tgtgtatcaa cctcatctga tgaattcata
    16861 acgcaaattc taagtttatt atcaatttgt atcaatgaaa tgtagatata tttattgaca
    16921 tacgaacatc gttcagctcc ctcaattgca ttatcaaaaa gattagaaag tatccggcaa
    16981 agcagcatat tatctatggg cactgattcg aacacattaa ttttagttgt aaattgtatg
    17041 tttttattca acgcctcctg ccatttcata ttgataatag catcaacggc tgaaatacct
    17101 gtgtagcata ttctgcccgc gtctgataag ctgtctgcta acttatccag atgctttatt
    17161 gcttcttttg gatttccatc actaaacatg gattttgcta cagatatctg attatttata
    17221 tcatgcttta actgccttat ctcattgtac ttgttttcaa tgagcatata attttcttct
    17281 tctgatttta gcctttgctc catgactttc attttcagtt ggtttgcata tgtatcaaaa
    17341 aagttaaata cgaacagatt gagcgccagt aatccaatca cagtaatcaa ataatttatc
    17401 gtctgtctgt gatttaaacc atatgataca aaaataccat tgagaataaa cacgcttaaa
    17461 ataggtatta gtataatcga cagccagttt ttgattggaa tatctttctg cttgtttttg
    17521 gaatattcta ttatgtaaac tgaaaaccaa aagcaaaaca atttagagca aaacatgccg
    17581 atatatcttc ctgctcctga agttaactgc tccaaaggac ttccaaaatt aagcatatat
    17641 aaaattccca tgggaagtga ttctgaagca agtattacta ttaaaaatat taatgaacaa
    17701 aatatttttg taccgaattt acattcaaac ataatgcttg aaattgccat catcaatata
    17761 aaagtagcaa tcaaatgaac ccatggatac tcaagaaata aagttaccga atcaagtgaa
    17821 ataaaacaga gtatcactgc cgggaccaat gatttttttc ggaatctata atcctctttc
    17881 atcatattgt acaaatagaa aactataacc atgctctccg caagacaatt cagactttct
    17941 ataattactt cactaatgga cattatcccc acctgtttct gctaaatttc aaaaaagctc
    18001 ttgtgatttt ttcaagatga tttctgctga catataagat tttgccgttc ttcataaata
    18061 cttgattttt tttaatgtag tcaatattag taacgtttat cagaacgctt ttatcggaac
    18121 gtacaaataa acattcttct aacattttct cataatctga taatttacct ttctgataat
    18181 attctttgtt aaaggtatgg atgacgatct gatgtgaata aacctctata tataaaatat
    18241 cgactgtaag aagttccttt tcaataccat cgtcaatgac ttttatgtat tttttatttc
    18301 tataatactc ttggattgta tcgctgagct gtttaaaata aataggttca ggttgatttt
    18361 ttaatatata tctaaacgcc ttaacttcat agccttgata aacgaatttg tcataaccgg
    18421 tcataaaaat aaggatcaca tttttatcaa gttgtcttat aaactctgcc gtctgtaaac
    18481 catttagatc tttcatctca atatcaagaa tgagcagatc atatttatca tttgaaaact
    18541 ctgcaataaa ttcttctcca ctttcaaact ctgaaaattc aaattcattt tcgtgcgttt
    18601 gaaatgattt tatatctttt tttatctttt ctatgtaaga tttttcatca tcacaaatag
    18661 cgattctcat aaaaacaccc ctaattatat tttagcacaa aattctaact ttttcaatat
    18721 taatcgtaat tttaacaaaa aaacaaatat gacttccttc tgggttaaaa aattacgact
    18781 tataaaaaat cttattcgca aaggtgcaga ttttgcgaaa gaaaaacagc tgatctatgc
    18841 attcacaagc acagatcagc tgtttttctt tattgtatat ccatatgatt ttcttctttc
    18901 tctcccaact ccattttctt tttgcgaata accctcatca gttttctgtc aactctgctt
    18961 tgtaggacct tatgatcgtt gtcataacta tcctgaatac acctactaag actaacaaac
    19021 aaactaaaaa tcgtatttgc aagcagatca ttctcaaact tcgatatgtt gtccagcata
    19081 gcctgtgcat actcgttgcc atcgtttgcg gactttgtaa accattcgat agcttgttcc
    19141 ttatcctttg taagttccgc tgcaccgaaa agatagatcc tgccaagctg ataacttgcc
    19201 caatgatttt tggcagcaca attctcaaaa taattgacag ctttttgtat atcatacttt
    19261 tcttcctgca aatacagctt tgcaagtgca tactgcgtat actcgctatc ttctgccaag
    19321 agcaaatact tttctgcttt gtccagattt tgaggcatta tctccccctg caaataaatt
    19381 ttgcctagtc tgtaactagc aatgacatct ccgctgtccg cacactcggt aagcaaggct
    19441 attccttttt caaagtcctg ttccaaatgc tctcctgaaa tatattcaag ggcgaggaat
    19501 ctttttgcat tgctgttttt aagtttgaca gctttctcaa ggatttttaa tgcactatct
    19561 gtatcttgcg gaatgtgttc acctatcaaa agtgctttgc catactcaaa caagccgttc
    19621 ttgttattca tttcagctga acgtctgaag tattcgatcg cttttgtaac gtctgagtct
    19681 gttccaagtc caaacttaaa catttgccct aatttgtaaa atagatcgtc gttcgccata
    19741 tcatcgtttt cgattttcaa aaatcccgac aaagcttgtt tgtaatatct ctgtgctgta
    19801 tcgttatctt tggtgacata ctctccatat ctgtacattt gagcaataga ataagccgca
    19861 tagggctgac cctgagagga tgatctctga taccaaagaa aagcctgtga cagatctttc
    19921 tccacaccgc tgccatagta atacagattt gcaaggctaa attgagcaaa cttgtttttc
    19981 tgttttgccg atctttcaaa ccactcaaag gctttttcat agtcctgctc cgtaccaaga
    20041 ccatagcaaa acattttacc tatacgatac tgaatatatg gctttatttt ctttgagttt
    20101 ggttctattt gcaaaaatcc ctgcaaagcc cgtgtgtatt ttgcaataga cgtttcttcg
    20161 ttcctttcgc caagcttgtc ggtagaataa agctttccaa gatcgtaaac agccaaaaca
    20221 tttccacgct gtgattcaga taacaaaagt tgttcagctt tcttaaaatc attgagctta
    20281 gcgtctttgc catagataag cttgcaggct tttttgtatt gatcgttcca tttgatatag
    20341 tattttattg ccgcagccga ttcatctgtt tctgtctctg ccaacggttc tgcttcatca
    20401 aacagaggtg acatactctg aggtgtgtta tcaaagtatt catcatttgg ttcagatcct
    20461 tcaatttcag tatttgcatc aaatggtttc atattaagta ctgtacgaat tatcatattc
    20521 cgcaccggct gaaaaacttt gttatctgct agttttggaa gttctgtttc cttttgggta
    20581 tacgtcttgt atttcaaacg ttcaagaccg caccatttct catagagctg ttgtatattt
    20641 tcatcttttg caagctctga aaatatttta ttgacggttt cctttatctc cattggaaga
    20701 tagccgtaaa cttttttgcc tttcacattc tgtaattgga tatatagttt tctgataagt
    20761 tcttcaagct gtggatctgt atgatcatta cttgcgatca tatttacaat gctttcaaat
    20821 tcgtttttgg aaaccgcttt caattcatca cggcttactg tctgttcctg ataaatgctt
    20881 tgcagatcat catgaaaaat atcgtttgca aataccgaac gcactttatc tattccagcc
    20941 tttgtcagaa agccttgctt tggatttgtt gaataaacaa gcaaatggat atgaggatga
    21001 tgagtagtat cgtggtaagc ggcgtaccac ttcaaattgc aaagtgggat attctgtgct
    21061 ttggcaatat ctgaaatatg ccttttcaca agctcacgcc aggcgtctga attatcaaag
    21121 ccaagcctta cagcatcctc acggcgaagt gaaacaacgt gtgaccaaac attgccttta
    21181 tgttcagcta tctcatttgc cgcttgattc agaattatag gctcgttctt ttcgttaaac
    21241 aagccgtgcg aacctctctt ttcaacgccc ggacgcatag ccatatatcc gacaaaattc
    21301 tgtcggtttc caaccacgtc tgcattgcgt tctactatcg tgcttatcaa ttcaccggca
    21361 ttctcaatgg tcggctctct ttcatagtcc tcatactcaa ggtatctttt ggattcagga
    21421 aagtcgttta tcaggtcgtt aataagctgc tcttgatttt tagttgcatt ggcatttctg
    21481 tcaacaaatt tttgacttcg tatctcgaca gtttcacggg tagcaatata ctttgtataa
    21541 tttctgcgtt ttgttttatt tttctgattt ccgcttttca gataacggct cgtaacgata
    21601 agctgcgaca ttttacacct tccttatgat aataagcacc acaaagttac atttcaccaa
    21661 ataattttga catttcacag cacgatgtat tcttatatga tataatatta ttagttataa
    21721 catatcactg aaagtccatt ttgtttcttg ggtgcttagt ctttaagatc tccttttgct
    21781 ttgatgatgt gacgtgcgtg tagatctgag tcgtggttat cgagctgtgg cccaacattc
    21841 tttgtatgta acgaatgtcc acgtcctctt ccaaaagcag agtcgcaaac gagtgacgga
    21901 acatatgtgg cgttatgtgc atttcaacac cgcattgatt gcaatatgaa ctcagcatat
    21961 ttcgtaccga ttgctctgtc attcttctgc cgagcttatt gacgaagaag taccctgaca
    22021 cggagatatt atcttcaaaa agaagtctgt accttttaag tatgctgaga acagccatat
    22081 tttccacggg tataaggcgt tcttttgaac ctttgccgta aaacttaacg gatcgtccta
    22141 aaagatcaac attttccggt ttaagagtac atatctcagc tatccttgca cctgtagcaa
    22201 aaagcaattc aattacagcg gcatttctga cggcacattt catttggtag gcactttggg
    22261 ctgaacctat ctgctgataa gaaaaggaaa ttatcttagc gatcacgtcg agaggtatcg
    22321 ttttgggcag cagcacaggc tctctgatcg aagtttcaag cttatcgaat gggttaaaat
    22381 ctatgtagtc ttgcaacagg agaaaatgga taaaagcttt tagcgtagca agcttacgct
    22441 ttacggtttt cggcttgtac tttttattca ggcactcgat ataatcccac aatgcttgtt
    22501 ttgaaagcgt atcggaaaac agtgcatact gcgaaaggtc gattttgtat gcacgcacag
    22561 ttttttcgct aagcttttta tggtaacggc agtaatcgag aaattggtct acaaaaggtc
    22621 tatattcaaa catcaaaaca gctccttaaa aatacttagg caaagcaatt tggtcaacat
    22681 tcacaaaagc acaaatgctt acgaataaat ttgcttttaa acctacctta tattatatca
    22741 gagttgtttg agttcgacaa atttagacga tttgtgaatt tttacaaagt tttcaaaagt
    22801 tgattgactt ttttaggaaa gtgtgatatg gtgttatatg tgacgagggt tattgaagga
    22861 taactcttta ttatcaactt aggagaaata aaatgtctga tttccaaaaa aattcaagta
    22921 actttgaaga tctgtgttta aaaatagtta aaaaactttt aggaaattca ttgaataaaa
    22981 taaaaaaaac gcagccatca aaagatggag gatatgatat tgatgcaaca ataaaatata
    23041 aaaataaaca gtacagcgta ttattcgaat gcaaactccg agggaaaaat gttaacttac
    23101 gagatattgc agcgaacgtc attattgcct ataacaattg taccgacagc ttagttttta
    23161 tgattaatca gtatttcact ccacaacttg aagaacaatt attgcgtttt agagattcaa
    23221 gtcaattgaa tataaaagta ttaataggat cagatattga aaatgtcatc cagaataaca
    23281 atatacctgt aagtacagag ttggctgagc ttttaaaaga taataataaa agcagaaaaa
    23341 acaaacatat atcatcactt gttttaaaca ctgattccga aaatatatgc aagcagatta
    23401 ttgaaaaacc acaagttaat tctgataata aagaatcaga ttttattgca caggtttatt
    23461 caaatgagct taatagagcc gtttcactac tcaaaaataa taaaagcttt attgttcaag
    23521 gctatattgg catgggcaaa agtgcttttg taagaaaaat attaaacact gtcgactgta
    23581 tgtgtataag gttaaatgcg gatgtgtgtc agaatcagga acaagtcatt cttcatttga
    23641 ttcgcaatat ttggggatta ccggacaata gttttttagg tatgtttgag gaagacgata
    23701 ttgattacat aactcgtact atcaatgaca attattctat ggaaacttgt aaatttataa
    23761 aatacatatt aaaccaaacc tctctttcta taaaaataga ggcaaactat atattatgtg
    23821 aatatttagt atgtataatg aaacgccatt atcctaaaac aaagtacgtt gtatattttg
    23881 ataattttca ttccgctaat caggaagtta atgatttctt tgtatatttg atcaatcttt
    23941 tttcggaaaa agacattcca tgtataattg aatatgattt atcagaatat gacctgcaaa
    24001 agcagaacct gatggcttat aacaaaataa ttaataaata tgccattata gatattgcca
    24061 ctctcactga agagcaagca aaaacttggt ttatccagga attgaatatc acagaaaaaa
    24121 ctgcgaatca aattgtaaaa agagtaggta cgcgatttta taatataaaa ttcatttccc
    24181 aaaatctaaa aagaagaatg catacgccaa acttcgaaaa agcaatggaa ttattggata
    24241 tgttgacacc aaacgatctg tccgatataa catcgcaaat aatcaactct tgtaagaaaa
    24301 aagataaaaa actattttat ctgctaaaaa tgttgaactg tcgcattccc attgatttgt
    24361 gttcatattt gaatttatca tacagttcac ttttaaaaga aggaatcatc gtcagagagg
    24421 atcgctatat atttgtctca aatgaatttg ttaaacaggc tgtaatgaaa gaaacgtctg
    24481 atttggtaaa tgagcaaaat atttccgaat tgattttaga tttctgtacc cataatcctg
    24541 gaaaatataa agatgtcata atatatggct tattttacgc aggcaaactg gaggaagcta
    24601 caaaagaaat agatttgtta atcaaagaac ttggtcaaaa gcgcaatttc acgttaatgt
    24661 tggaattcat tgaacttgca ataactattt ctgaaaataa caaaaatgct cacgcactgt
    24721 caaactattt aataaaaaag cttgaagtat atgcaatcat taaatcactt atgttggaca
    24781 aggcaagatt gacattagac cacttgcaaa cattggtgaa ttcgggacag ttggacttac
    24841 ttgatgaatc ctattcagaa ttagcaatct gctattttaa gggtactatc gcactcaaag
    24901 actatgcatt ttcagatgat cttctgaatg aacattataa gtactttaaa aactgcatag
    24961 atggattaat gaaagataat ccggatgatt atcttggaaa ggtgtgcagc aattacgcaa
    25021 tctacataaa agaaaccaag ggcaattctg cggcactgga agtttttggt gcagctttga
    25081 aggctttacc taattcccag accctgtata ttgaacatct cagtcatctt gcctgcattt
    25141 cattgtcata cgaaccccaa aagtcatatg aatattacag taaaataata gaaaaagtaa
    25201 acaacagcca aaccttctac tgcttcccct ttcacgaata tggggacaag gctatgtgca
    25261 aagtgctttt gaaagaggtt aataaggccg tctctcattc tgaccttggc atcaaatatg
    25321 ctgaatcgca cggcgtattt gatgaagttg gaagaatact taatataaaa ggctgcgctt
    25381 ttttactggc tgacaaagta tcggaagctg taaaatgctt taaagaagcg acagaaataa
    25441 tggagtattc aggatataag cactatagtt ggcgtagcaa actaaattat gtaaactatt
    25501 ttatcacttc tggaaacaaa gaagaattaa taaaaatgct atacgatgcg tacagcattt
    25561 ttaaatccgg attaattaca aaagttcaaa acctaattga atcatgtgat gattttatct
    25621 ccagtaggga atacctggtg cttcttgttg taggcaagtg cagccagcta ttatttgaca
    25681 caaaagcaag tcaaagagca gattatatct cggctgaaaa aatagctgat gaattcagat
    25741 ttcctgacaa aataaaaaaa cattacctca agacaataaa tcagctcatt aatcatcacg
    25801 aacagcttga actgaaaagc atttatattt ataatggaga tatttttatt attggataga
    25861 ttctaaaagg aaaagctcgt tttgctttgc aaatgaatac aaaaagcagt tatcagccga
    25921 aggtgattga gaagaaaaag ctgaaatagc gtttcttttg gcggaaacag cttctttgtt
    25981 tccataaaca tagatccagt gaaaagtggt aagattttta ggcggttgga aaatatcact
    26041 ttttctattt ggccaaacat cttcattttc agtatgtatc aaataagaaa gaacttttat
    26101 gggatgatta atgattctta gtgcatcata taaatacatt gcacaggcat aatgatcccc
    26161 atgcaaatca aatattgacg gggctgcgat taaactcggc gaacatgatc ttattgcgta
    26221 taccaagtcg tcaaggaaat tctgacttgt gtattcagct tgagtttccg tatgcaaaga
    26281 atggacagtt tccttattcg ccggatgata tgtacaagat gatacaggag aattttgctg
    26341 ttcaggagtg cttcttaagc gcattagaaa gctt
//
