LOCUS       c00046_NZ_FQYT..       17474 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_FQYT01000012.1 Parasporobacterium paucivorans DSM 15970, whole
            genome shotgun sequence.
ACCESSION   NZ_FQYT01000012
VERSION     NZ_FQYT01000012
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 13:26:24
            Original ID  :: NZ_FQYT01000012.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17474
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17474
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[6653:7474]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      6654..7474
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..17474
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17474
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(233..634)
                     /locus_tag="ctg46_1"
                     /transl_table=11
                     /translation="MEYSEILLGIIRLLQRKYNIISEILGLTKELGEAISRNDQVSIQM
                     VLEMRKEEMDKADACDKAISLMTNCLPREEGDLVRSCLKPDAPDGIQKNDYRKIIEISE
                     NIHSVIARCVEIDKVMNRRVAGAASYYTD"
     CDS             complement(646..1017)
                     /locus_tag="ctg46_2"
                     /transl_table=11
                     /translation="MNMQAYQQYKEQSVHTMTQSELLLLVLDELVKRLLRAELSLEQNN
                     FELFDQSVNRSVEIVRYLKKTLNHQYEVSGQLSRMYDFFLYELSRIQASRNGKLIQELK
                     PLAEDLRGTFREAARQVYN"
     PFAM_domain     complement(667..1002)
                     /aSDomain="FliS"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02561.16"
                     /description="Flagellar protein FliS"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_2_0001"
                     /evalue="4.60E-24"
                     /label="ctg46_2"
                     /locus_tag="ctg46_2"
                     /protein_end="117"
                     /protein_start="5"
                     /score="85.0"
                     /tool="antismash"
                     /translation="YQQYKEQSVHTMTQSELLLLVLDELVKRLLRAELSLEQNNFELFD
                     QSVNRSVEIVRYLKKTLNHQYEVSGQLSRMYDFFLYELSRIQASRNGKLIQELKPLAED
                     LRGTFREA"
     CDS             complement(1049..3394)
                     /locus_tag="ctg46_3"
                     /transl_table=11
                     /translation="MSNISSTTGPSSASTIRGYGGLASGLDTDSLIKGMTIGIQAKIDK
                     QEQSKQLLEWKMEACRTISSAMINFSNKYTSYTSKNNLSSASFFARNNIASVGKNSGCV
                     SVTGGLSGAASFSVAGVKQLAMDASATSASAASDQVLRTGLIATDLTTERTINNLEGET
                     LTFTYGTESYAVKLETGTMDGIEYKYDNMANATASINKALSNVSVGTGLTLADIMTVTA
                     DDTKFTLKELDAHGNLLALKSGSDSVLADMGFTADSAITVGGITGTEAILSHPEKTSDL
                     LAGKSISFTYNGITKKLTMPAADQITTMDRLMEDVQRSMGSAFGSGRVKVSLNTVGEYS
                     SFSFAAIRPDGSPDASSVLEISGADSGLLGPDGILGISAGESNRLNLGASLLESGLAAG
                     LGTKTESDPLLLTINNVEIQGLTYGSTMKEVMEAINKTEGANVEISYLANADKFTFKST
                     ASGASGNVEIGGESASVFGSMNSVSGQDALVTVRYTGSNETMDIVRGTNTFTLDGLNVT
                     VKSAFGYTEAPAGVFTEVPDNEEIQFTATVDSDEIVGSVKQMIEDYNGILDMVNSQLST
                     KRNRDYLPLTDSQKEEMTDDKIEKWEGKTKAGLLFNDSTLRSLYDDFRFLFSSGSADKA
                     ALGTMGISVSTSYSDNGKLVLDETALKRAIESDPESVKDVFTRTENKTTGEAGGLMAKI
                     STILKEYAGTTGASKGILIQRAGSASAPASVLNNTIQKEIDSAERNVERLKDQMKLQTD
                     RYIKKFTSLETLISQMNSQSSWLSSALG"
     PFAM_domain     complement(1082..1945)
                     /aSDomain="FliD_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07195.14"
                     /description="Flagellar hook-associated protein 2
                     C-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_3_0003"
                     /evalue="2.10E-35"
                     /label="ctg46_3"
                     /locus_tag="ctg46_3"
                     /protein_end="771"
                     /protein_start="483"
                     /score="122.4"
                     /tool="antismash"
                     /translation="GQDALVTVRYTGSNETMDIVRGTNTFTLDGLNVTVKSAFGYTEAP
                     AGVFTEVPDNEEIQFTATVDSDEIVGSVKQMIEDYNGILDMVNSQLSTKRNRDYLPLTD
                     SQKEEMTDDKIEKWEGKTKAGLLFNDSTLRSLYDDFRFLFSSGSADKAALGTMGISVST
                     SYSDNGKLVLDETALKRAIESDPESVKDVFTRTENKTTGEAGGLMAKISTILKEYAGTT
                     GASKGILIQRAGSASAPASVLNNTIQKEIDSAERNVERLKDQMKLQTDRYIKKFTSLET
                     LISQMNS"
     PFAM_domain     complement(3020..3325)
                     /aSDomain="FliD_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02465.20"
                     /description="Flagellar hook-associated protein 2
                     N-terminus"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_3_0002"
                     /evalue="8.10E-13"
                     /label="ctg46_3"
                     /locus_tag="ctg46_3"
                     /protein_end="125"
                     /protein_start="23"
                     /score="49.0"
                     /tool="antismash"
                     /translation="SGLDTDSLIKGMTIGIQAKIDKQEQSKQLLEWKMEACRTISSAMI
                     NFSNKYTSYTSKNNLSSASFFARNNIASVGKNSGCVSVTGGLSGAASFSVAGVKQLA"
     CDS             3499..4275
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 207.4; E-value: 4.6e-63)"
                     /gene_kind="other"
                     /locus_tag="ctg46_4"
                     /transl_table=11
                     /translation="LATVIVLTNQKGGVGKTTTSSALAAGLALHNNRVLAVDMDPQGNL
                     GFSLGLDIENSSNIYDVLTGKLPIQSTIQSTRYCDVITSNIMLSSAEMGFTGSGRESLL
                     YTALKPIQDCYDYIVIDTPPALNILTVNAYTAASHLIIPMVPEILSLLGVSQLKETIAS
                     VKSAFNPNLNILGILLTRYNGRTLLAQEVKEMAEIIAGQISSIVFDTQIRTSVSVAEAP
                     AQGESIFDYAPRCKPAEDYSCFVKEVIARIKRQEVS"
     PFAM_domain     3505..4020
                     /aSDomain="AAA_31"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13614.8"
                     /description="AAA domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_4_0004"
                     /evalue="3.30E-49"
                     /label="ctg46_4"
                     /locus_tag="ctg46_4"
                     /protein_end="174"
                     /protein_start="2"
                     /score="167.3"
                     /tool="antismash"
                     /translation="TVIVLTNQKGGVGKTTTSSALAAGLALHNNRVLAVDMDPQGNLGF
                     SLGLDIENSSNIYDVLTGKLPIQSTIQSTRYCDVITSNIMLSSAEMGFTGSGRESLLYT
                     ALKPIQDCYDYIVIDTPPALNILTVNAYTAASHLIIPMVPEILSLLGVSQLKETIASVK
                     SAFNPNLNI"
     CDS             4276..4830
                     /locus_tag="ctg46_5"
                     /transl_table=11
                     /translation="MPRKSSKTTHVLNLLSGSEEHDESSITDCADSGAPDQITVVMPKK
                     SADPVADIIRARLEEEFSPTELDEQPQPPELAPVGADKNEPLEQISEKPQGVDYAYVNV
                     MEHIIQEEVEGFCQEFETCTCSRCLADIAALALTNLPPKYIVKDCLTISPLLNYYRSKY
                     SSQVTVSLTKSSMSVKDKPRH"
     PFAM_domain     4579..4821
                     /aSDomain="ComFB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10719.11"
                     /description="Late competence development protein ComFB"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_5_0005"
                     /evalue="1.10E-15"
                     /label="ctg46_5"
                     /locus_tag="ctg46_5"
                     /protein_end="182"
                     /protein_start="101"
                     /score="57.5"
                     /tool="antismash"
                     /translation="VNVMEHIIQEEVEGFCQEFETCTCSRCLADIAALALTNLPPKYIV
                     KDCLTISPLLNYYRSKYSSQVTVSLTKSSMSVKDKP"
     CDS             complement(4893..6557)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:diguanylate cyclase (Score: 155.2; E-value:
                     6e-47)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_6"
                     /transl_table=11
                     /translation="MEKSISNLGEAKQGQIRTMFFTFKMLALFFSAIPLFQYFSAKLNI
                     DFVNNNYSVYAIGLTLIVICLVMFFLFFVFNRSEKNKFLQVLEVVIFLAVFITVIVVSG
                     ANESYYKFIFLFVIVSFTIEHGMKLGLIIASIASGAVILMDILMGGTRGVNRYFEDDIA
                     LIVMFFLVAWTLGYYVKLEKSHIDELTEYANIDGLTGAYNHRCFYDMISIMYDESIQHD
                     AALSLVMIDLDYFKKYNDMNGHNKGDELLKEISEVLKMCLRQEDILFRYGGDEFCVLMP
                     GICQDEAAQVADNLRNAVSIYGFPGQEYLPNRKMTVSVGVASLTEETENYNDFIAEADR
                     ALYRAKFLRRNKVEVYSSIFDQTGSSGGDGLTEVMKPLKTLITVINSRDSYTFNHVDRV
                     YNYSEIMANHLKLADHEKKKLLYAAYLHDLGKINVSKEVLVADNNLTPEQWEELRKHPV
                     DSAAIIEQIEGLEEVVPIVLQHHEKFDGTGYPQGLKGGEISYLARILTVIDSFDAMTNH
                     RTYQETKTFEEAFEEIERCKGTQFDPVIASQFMEAIG"
     PFAM_domain     complement(5016..5384)
                     /aSDomain="HD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01966.24"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_6_0007"
                     /evalue="1.10E-19"
                     /label="ctg46_6"
                     /locus_tag="ctg46_6"
                     /protein_end="514"
                     /protein_start="391"
                     /score="70.9"
                     /tool="antismash"
                     /translation="TFNHVDRVYNYSEIMANHLKLADHEKKKLLYAAYLHDLGKINVSK
                     EVLVADNNLTPEQWEELRKHPVDSAAIIEQIEGLEEVVPIVLQHHEKFDGTGYPQGLKG
                     GEISYLARILTVIDSFDAM"
     aSDomain        complement(5493..5990)
                     /aSDomain="TIGR00254"
                     /aSTool="tigrfam"
                     /description="GGDEF: diguanylate cyclase (GGDEF) domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg46_6_0001"
                     /evalue="2.50E-46"
                     /identifier="TIGR00254"
                     /label="ctg46_6"
                     /locus_tag="ctg46_6"
                     /protein_end="355"
                     /protein_start="189"
                     /score="155.4"
                     /tool="antismash"
                     /translation="TEYANIDGLTGAYNHRCFYDMISIMYDESIQHDAALSLVMIDLDY
                     FKKYNDMNGHNKGDELLKEISEVLKMCLRQEDILFRYGGDEFCVLMPGICQDEAAQVAD
                     NLRNAVSIYGFPGQEYLPNRKMTVSVGVASLTEETENYNDFIAEADRALYRAKFLRRNK
                     VEV"
     PFAM_domain     complement(5505..5981)
                     /aSDomain="GGDEF"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00990.23"
                     /description="Diguanylate cyclase, GGDEF domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_6_0006"
                     /evalue="4.90E-42"
                     /label="ctg46_6"
                     /locus_tag="ctg46_6"
                     /protein_end="351"
                     /protein_start="192"
                     /score="143.5"
                     /tool="antismash"
                     /translation="ANIDGLTGAYNHRCFYDMISIMYDESIQHDAALSLVMIDLDYFKK
                     YNDMNGHNKGDELLKEISEVLKMCLRQEDILFRYGGDEFCVLMPGICQDEAAQVADNLR
                     NAVSIYGFPGQEYLPNRKMTVSVGVASLTEETENYNDFIAEADRALYRAKFLRRN"
     CDS             complement(6654..6782)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_7"
                     /sec_met_domain="TIGR04223 (E-value: 6.6e-14, bitscore:
                     44.0, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTRILAAVTALATLFAGTIATSACFWYFYQPEEPKCLNDR"
     aSDomain        complement(6666..6767)
                     /aSDomain="TIGR04223"
                     /aSTool="tigrfam"
                     /description="quorum_AgrD: cyclic lactone autoinducer
                     peptide"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg46_7_0002"
                     /evalue="3.90E-12"
                     /identifier="TIGR04223"
                     /label="ctg46_7"
                     /locus_tag="ctg46_7"
                     /protein_end="39"
                     /protein_start="5"
                     /score="44.0"
                     /tool="antismash"
                     /translation="ILAAVTALATLFAGTIATSACFWYFYQPEEPKCL"
     CDS             complement(6836..7474)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_8"
                     /sec_met_domain="AgrB (E-value: 3.5e-35, bitscore: 113.3,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERWAKRTAERISLQMKYDEDKKAVIAYGLTAMIQMATIFVIISI
                     FGLFFGFWMESVVIFLGVGIIRKSTGGAHSATMLGCILISVSSISLLSAAARYIFDISI
                     NIYLNCFVSIFIYLLCFVVFYLRVPVDTPNKPIVKPEKIKRLRKQSFLILTAFFLLSMV
                     CVFLTGWNTRFFSLAVIIRLTMLWQALTLTRLGQVFFAWIDVGFRGVSA"
     PFAM_domain     complement(6899..7459)
                     /aSDomain="AgrB"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04647.17"
                     /description="Accessory gene regulator B"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_8_0008"
                     /evalue="7.00E-33"
                     /label="ctg46_8"
                     /locus_tag="ctg46_8"
                     /protein_end="192"
                     /protein_start="5"
                     /score="113.6"
                     /tool="antismash"
                     /translation="KRTAERISLQMKYDEDKKAVIAYGLTAMIQMATIFVIISIFGLFF
                     GFWMESVVIFLGVGIIRKSTGGAHSATMLGCILISVSSISLLSAAARYIFDISINIYLN
                     CFVSIFIYLLCFVVFYLRVPVDTPNKPIVKPEKIKRLRKQSFLILTAFFLLSMVCVFLT
                     GWNTRFFSLAVIIRLTMLWQALTL"
     CDS             complement(7446..7952)
                     /locus_tag="ctg46_9"
                     /transl_table=11
                     /translation="MELFKIILFEYLLGYALQGFIIVLGIYAFNRKRIEVKSYVLTSLL
                     TIIVSFLVRMLPISFGVHTILNMLFLFLICIMFLKMPGFSTIRSALLVTVILLVSEMAN
                     VAVVISIIGKAKFENQMLFSSNRAIIGLPGALFFAVLIILAYYFSNYRLRGRNGIDGKM
                     GEENC"
     CDS             complement(7939..8505)
                     /locus_tag="ctg46_10"
                     /transl_table=11
                     /translation="MLVFLLLAFLCGKLKGYRLRPLMKAYVLYPYFAIELLYIFLQGSV
                     FMGNYDFIMYSAILNNIFLFALIIPIMFFKLYKQGLLGAGLIIAGTFLNKFVMIQNGGK
                     MPVYPSLSKITGYFDASAIQTADSIHILGNESVRFKFLTDYIDVGYSIMSIGDLLIHSF
                     VFITVYYSIKELNKKLEREKIYGII"
     PFAM_domain     complement(7999..8442)
                     /aSDomain="DUF5317"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17248.4"
                     /description="Family of unknown function (DUF5317)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_10_0009"
                     /evalue="1.30E-23"
                     /label="ctg46_10"
                     /locus_tag="ctg46_10"
                     /protein_end="169"
                     /protein_start="21"
                     /score="83.8"
                     /tool="antismash"
                     /translation="LMKAYVLYPYFAIELLYIFLQGSVFMGNYDFIMYSAILNNIFLFA
                     LIIPIMFFKLYKQGLLGAGLIIAGTFLNKFVMIQNGGKMPVYPSLSKITGYFDASAIQT
                     ADSIHILGNESVRFKFLTDYIDVGYSIMSIGDLLIHSFVFITVY"
     CDS             complement(8619..9875)
                     /locus_tag="ctg46_11"
                     /transl_table=11
                     /translation="MDKIRVNLYELLLCLSNAQDLAADGAVNHQQEVACLSYHLAEELR
                     LSNQEKSEIFLASLIHDLGVLSTEERRRISMDEPAGICDHAFRGARLMEKFSPMGKPAN
                     IVRYHHLPWDSGTGRQFKGQEVPFGSHIIHLADRTCLKINKSENILSQLPGVLAEIRKE
                     ENSRFMPAVVDALEAISKKEYIWLDIMSVSPVNTLPLGDNKKFILEMGDIISLAKVFSH
                     IIDFRSKFTARHSAGVAKTAEKLGELIGFSPMECKMLLVAGYLHDIGKLAIDNDVLEKP
                     TSLNEDEFNEIRSHAYYTYRLLETIPQFNTINVWASYHHERLDGKGYPFHIPGENLALG
                     SRVMAVADVFTAVTENRPYREGMRDDKAATLLINQAEDGALDGRIVKLLIDNFQEINDL
                     RVDSQQMASKEYEKWSEKY"
     PFAM_domain     complement(8820..9182)
                     /aSDomain="HD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01966.24"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_11_0011"
                     /evalue="5.10E-16"
                     /label="ctg46_11"
                     /locus_tag="ctg46_11"
                     /protein_end="352"
                     /protein_start="231"
                     /score="59.1"
                     /tool="antismash"
                     /translation="ARHSAGVAKTAEKLGELIGFSPMECKMLLVAGYLHDIGKLAIDND
                     VLEKPTSLNEDEFNEIRSHAYYTYRLLETIPQFNTINVWASYHHERLDGKGYPFHIPGE
                     NLALGSRVMAVADVFTA"
     PFAM_domain     complement(9459..9794)
                     /aSDomain="HD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01966.24"
                     /description="HD domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_11_0010"
                     /evalue="9.30E-08"
                     /label="ctg46_11"
                     /locus_tag="ctg46_11"
                     /protein_end="139"
                     /protein_start="27"
                     /score="32.4"
                     /tool="antismash"
                     /translation="NHQQEVACLSYHLAEELRLSNQEKSEIFLASLIHDLGVLSTEERR
                     RISMDEPAGICDHAFRGARLMEKFSPMGKPANIVRYHHLPWDSGTGRQFKGQEVPFGSH
                     IIHLADRT"
     CDS             complement(9904..10695)
                     /locus_tag="ctg46_12"
                     /transl_table=11
                     /translation="MEEINSPVVLALIGTGITFLATVIGAATVFFVAAEAGGKVQKTFL
                     GFASGVMIAASVWSLLLPAIEMSKEKGDIEWLPAALGFISGGIFLFLLDKFLPHLHADA
                     ERPEGIKSKMPRSTLLVLAVTLHNIPEGMAVGLAFAMASKSSAALTGAFVLATGMALQN
                     LPEGAAISLPLRGEGFSKQKSFLFGAASGIVEPMAGLLGVLLAVAVVNIMPFMLSFAAG
                     AMIYVVVDELVPEAYSKHSNIGTLGAMAGFVLMMVLDIAFT"
     PFAM_domain     complement(9922..10368)
                     /aSDomain="Zip"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02535.24"
                     /description="ZIP Zinc transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_12_0012"
                     /evalue="1.40E-16"
                     /label="ctg46_12"
                     /locus_tag="ctg46_12"
                     /protein_end="258"
                     /protein_start="109"
                     /score="60.7"
                     /tool="antismash"
                     /translation="IKSKMPRSTLLVLAVTLHNIPEGMAVGLAFAMASKSSAALTGAFV
                     LATGMALQNLPEGAAISLPLRGEGFSKQKSFLFGAASGIVEPMAGLLGVLLAVAVVNIM
                     PFMLSFAAGAMIYVVVDELVPEAYSKHSNIGTLGAMAGFVLMMVL"
     CDS             complement(10712..11263)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1159:dihydropteridine reductase (Score: 53.1; E-value:
                     4.9e-16)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_13"
                     /sec_met_domain="PF00881 (E-value: 1.8e-14, bitscore: 46.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERHFDYDIMTEIKERWSARALAPGRIDREEVFALLEAARYAPSC
                     FNEQPWRFVLADEEGSLDRMRGILTESNQRWANKAPVLILIVSKKTFNHNGKDNYWHMF
                     DAGTAWGYLSLEAWRRGLVAHPMAGFKREEARDIFNIPQEYDIITVIAVGKHGLKEDLE
                     PDLQEREHPDTRKEIRELLL"
     PFAM_domain     complement(10799..11056)
                     /aSDomain="Nitroreductase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00881.26"
                     /description="Nitroreductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_13_0014"
                     /evalue="2.80E-12"
                     /label="ctg46_13"
                     /locus_tag="ctg46_13"
                     /protein_end="155"
                     /protein_start="69"
                     /score="47.1"
                     /tool="antismash"
                     /translation="TESNQRWANKAPVLILIVSKKTFNHNGKDNYWHMFDAGTAWGYLS
                     LEAWRRGLVAHPMAGFKREEARDIFNIPQEYDIITVIAVGK"
     PFAM_domain     complement(11042..11227)
                     /aSDomain="Nitroreductase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00881.26"
                     /description="Nitroreductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_13_0013"
                     /evalue="2.40E-11"
                     /label="ctg46_13"
                     /locus_tag="ctg46_13"
                     /protein_end="74"
                     /protein_start="12"
                     /score="44.1"
                     /tool="antismash"
                     /translation="IKERWSARALAPGRIDREEVFALLEAARYAPSCFNEQPWRFVLAD
                     EEGSLDRMRGILTESNQ"
     CDS             complement(11274..11759)
                     /locus_tag="ctg46_14"
                     /transl_table=11
                     /translation="MNSLEFAIKMEEDGAKYYMEQAELHEGNGMCVVCAKLAEEEKKHA
                     SLLKARLEGKAYQLDDRDTFTEIMNVFESAVDVRILGKLIPSQVDFYRAGLEFEKKSID
                     LYTEFLKNAQSDDEKELFRFLINQEKLHFSILDEIDRMLTNAEEWVENAEFGLREEY"
     PFAM_domain     complement(11349..11753)
                     /aSDomain="Rubrerythrin"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02915.19"
                     /description="Rubrerythrin"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_14_0015"
                     /evalue="1.10E-14"
                     /label="ctg46_14"
                     /locus_tag="ctg46_14"
                     /protein_end="137"
                     /protein_start="2"
                     /score="55.1"
                     /tool="antismash"
                     /translation="SLEFAIKMEEDGAKYYMEQAELHEGNGMCVVCAKLAEEEKKHASL
                     LKARLEGKAYQLDDRDTFTEIMNVFESAVDVRILGKLIPSQVDFYRAGLEFEKKSIDLY
                     TEFLKNAQSDDEKELFRFLINQEKLHFSILD"
     CDS             complement(11779..12462)
                     /locus_tag="ctg46_15"
                     /transl_table=11
                     /translation="MDLRILVTAIICVLYLLVLLPIYIWMDRKRESVETPGYKLVLSGI
                     FCVLGLAAVFVHDFSIFPLLILGGLILAMIGDYFLVFLFADEKRFICGILAFSVTQVFY
                     IAGMIVLSGIGIGEFIMTILVLSAILIVVLKMKPDFGKARLPINIYTALVTLMAAKAVM
                     MLLAGERVMTLQWMFSMGALLFWVSDMFLGINRFIKKRRIFSTLVAVCYFLGQLMIAIS
                     VYYQQ"
     PFAM_domain     complement(11794..12324)
                     /aSDomain="YhhN"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF07947.16"
                     /description="YhhN family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_15_0016"
                     /evalue="1.10E-27"
                     /label="ctg46_15"
                     /locus_tag="ctg46_15"
                     /protein_end="223"
                     /protein_start="46"
                     /score="96.9"
                     /tool="antismash"
                     /translation="CVLGLAAVFVHDFSIFPLLILGGLILAMIGDYFLVFLFADEKRFI
                     CGILAFSVTQVFYIAGMIVLSGIGIGEFIMTILVLSAILIVVLKMKPDFGKARLPINIY
                     TALVTLMAAKAVMMLLAGERVMTLQWMFSMGALLFWVSDMFLGINRFIKKRRIFSTLVA
                     VCYFLGQLMIAISV"
     CDS             complement(12475..13188)
                     /locus_tag="ctg46_16"
                     /transl_table=11
                     /translation="MQNKKYENSIKMRQITRITPQGRFCAEDCILLEERYTMEINGVNC
                     GEFFCLPDNLLQLACGHGLAKGLIGMQDEVAEFMVDEDARGLCLRTSPAAEEKSRKEIN
                     AVFSPDDVHRLNQAFNRKCYLFHKTGAAHSVALADRDGILIFMEDVARHNALDKVIGEM
                     FLQGLTPEGKMLIFSGRLAQDMIGKILSCGVKVLVAPGAPTLAAVHLAEMNKITMMGFV
                     RKDHINIYTSPERIL"
     PFAM_domain     complement(12481..12903)
                     /aSDomain="FdhD-NarQ"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02634.17"
                     /description="FdhD/NarQ family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_16_0017"
                     /evalue="3.40E-44"
                     /label="ctg46_16"
                     /locus_tag="ctg46_16"
                     /protein_end="236"
                     /protein_start="95"
                     /score="151.4"
                     /tool="antismash"
                     /translation="EEKSRKEINAVFSPDDVHRLNQAFNRKCYLFHKTGAAHSVALADR
                     DGILIFMEDVARHNALDKVIGEMFLQGLTPEGKMLIFSGRLAQDMIGKILSCGVKVLVA
                     PGAPTLAAVHLAEMNKITMMGFVRKDHINIYTSPERI"
     aSDomain        complement(12481..13110)
                     /aSDomain="TIGR00129"
                     /aSTool="tigrfam"
                     /description="fdhD_narQ: formate dehydrogenase family
                     accessory protein FdhD"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg46_16_0003"
                     /evalue="4.80E-43"
                     /identifier="TIGR00129"
                     /label="ctg46_16"
                     /locus_tag="ctg46_16"
                     /protein_end="236"
                     /protein_start="26"
                     /score="145.2"
                     /tool="antismash"
                     /translation="EDCILLEERYTMEINGVNCGEFFCLPDNLLQLACGHGLAKGLIGM
                     QDEVAEFMVDEDARGLCLRTSPAAEEKSRKEINAVFSPDDVHRLNQAFNRKCYLFHKTG
                     AAHSVALADRDGILIFMEDVARHNALDKVIGEMFLQGLTPEGKMLIFSGRLAQDMIGKI
                     LSCGVKVLVAPGAPTLAAVHLAEMNKITMMGFVRKDHINIYTSPERI"
     CDS             complement(13216..13854)
                     /locus_tag="ctg46_17"
                     /transl_table=11
                     /translation="MKIKRLDMDSYPRIKHFEYFRSLHNPYAGVTANVDITELLAEIKS
                     RKYAFFHTIIYLAVSAANQIPQLRQRIEGDEIIEYEHCGASYTVALEDGTYCHCRLDFN
                     MPFKDFLEDAGKRQSLAIQDPSIEDVTETGSLYFVSSVPWVSYTGLTQPTPYPADSNPR
                     ITFGRFFIQDGRVLMPTTLLVNHALADGKHIASFFENLENEARTLDLLQ"
     PFAM_domain     complement(13252..13845)
                     /aSDomain="CAT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00302.20"
                     /description="Chloramphenicol acetyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_17_0018"
                     /evalue="1.30E-27"
                     /label="ctg46_17"
                     /locus_tag="ctg46_17"
                     /protein_end="201"
                     /protein_start="3"
                     /score="97.1"
                     /tool="antismash"
                     /translation="KRLDMDSYPRIKHFEYFRSLHNPYAGVTANVDITELLAEIKSRKY
                     AFFHTIIYLAVSAANQIPQLRQRIEGDEIIEYEHCGASYTVALEDGTYCHCRLDFNMPF
                     KDFLEDAGKRQSLAIQDPSIEDVTETGSLYFVSSVPWVSYTGLTQPTPYPADSNPRITF
                     GRFFIQDGRVLMPTTLLVNHALADGKHIASFFENL"
     CDS             complement(13870..15066)
                     /locus_tag="ctg46_18"
                     /transl_table=11
                     /translation="MTIATLKKGEGRTIKAGGMWVFDNEIETVLGSFEDGDIVQVHDFD
                     GFPMGKGFINSNSKIRIRMMTRNKEQEIDEAFLRMRVQNAWDYRKKTVDTSSCRIIFGE
                     ADFLPGLIVDKFSDVLVVESLALGIDRLKDTILKCLRSILEADGIQIRGIFERSDAKVR
                     ENEGMERFKGFIGPEFDTNVEITENGVRYIVDVKEGQKTGFFLDQKYNRLAVGRLCKGA
                     KVLDCFTHTGSFALNAGLAEAGSVLGIDASELGIAQARENAKLNGLENIVHFQCANVFE
                     LLPEMEEKGEKFDVIILDPPAFTKSRNSVKNAIKGYREINLRAMKLLKDGGFLATCSCS
                     HFMTYELFTQTLHQASRNVHKRLRQVEYRTQAPDHPILWAADESYYLKFYIFQVCDEK"
     PFAM_domain     complement(13984..14535)
                     /aSDomain="Methyltrans_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF10672.11"
                     /description="S-adenosylmethionine-dependent
                     methyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_18_0020"
                     /evalue="5.60E-23"
                     /label="ctg46_18"
                     /locus_tag="ctg46_18"
                     /protein_end="361"
                     /protein_start="177"
                     /score="81.6"
                     /tool="antismash"
                     /translation="EFDTNVEITENGVRYIVDVKEGQKTGFFLDQKYNRLAVGRLCKGA
                     KVLDCFTHTGSFALNAGLAEAGSVLGIDASELGIAQARENAKLNGLENIVHFQCANVFE
                     LLPEMEEKGEKFDVIILDPPAFTKSRNSVKNAIKGYREINLRAMKLLKDGGFLATCSCS
                     HFMTYELFTQTLHQASRNVHK"
     PFAM_domain     complement(14866..15054)
                     /aSDomain="PUA_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17785.3"
                     /description="PUA-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_18_0019"
                     /evalue="5.10E-20"
                     /label="ctg46_18"
                     /locus_tag="ctg46_18"
                     /protein_end="67"
                     /protein_start="4"
                     /score="71.2"
                     /tool="antismash"
                     /translation="TLKKGEGRTIKAGGMWVFDNEIETVLGSFEDGDIVQVHDFDGFPM
                     GKGFINSNSKIRIRMMTR"
     CDS             complement(15092..15970)
                     /locus_tag="ctg46_19"
                     /transl_table=11
                     /translation="VKKIAVCIMFAGILLQLLSCSAAKKEGTTENTVPNIIESMTQETS
                     GIPAETNTMPPETGPQDPAVDTQTASPESSGRSPEVEAGGIVVAIDAGHQRHGDSEPEP
                     IGPGASQTKAKVSSGTTGRFSGLPEYELNLQVALKLKALLLARGYQVIMIRETNDVDIS
                     NAQRAEAANNNGADAFVRIHANGSENPETNGVMMICPTPSNPYCGNLYGECRRLSECIL
                     NMVLYSTGAGDKGVWETDTMSGINWCQVPATIIEMGYMTNQTEDMLLSTQAYQYEIAEG
                     ITAGLDDYFVK"
     PFAM_domain     complement(15110..15709)
                     /aSDomain="Amidase_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01520.20"
                     /description="N-acetylmuramoyl-L-alanine amidase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg46_19_0021"
                     /evalue="6.60E-37"
                     /label="ctg46_19"
                     /locus_tag="ctg46_19"
                     /protein_end="287"
                     /protein_start="87"
                     /score="127.3"
                     /tool="antismash"
                     /translation="VAIDAGHQRHGDSEPEPIGPGASQTKAKVSSGTTGRFSGLPEYEL
                     NLQVALKLKALLLARGYQVIMIRETNDVDISNAQRAEAANNNGADAFVRIHANGSENPE
                     TNGVMMICPTPSNPYCGNLYGECRRLSECILNMVLYSTGAGDKGVWETDTMSGINWCQV
                     PATIIEMGYMTNQTEDMLLSTQAYQYEIAEGITAGLD"
ORIGIN
        1 gtatttacaa gcggcgtaaa aactgccagt aggttatcta ctggcagaaa agatttatat
       61 tttttcaatt gtctacttga cgggaagcag ttcaacatag ctgcaagggc gaatttaaaa
      121 attttgtatc aaacttgtat caaaaatgaa ttctatacca ctaaaagtct tgaaaacaat
      181 ggatcgtacg tattccatat gccatatatt atgcatggct ttttttattt cgtcaatccg
      241 tataatagga ggcggcccca gccacccggc ggttcatgac cttgtctatt tccacgcagc
      301 gggcaataac gctatgaata ttttcgctga tctcgatgat tttcctgtag tcatttttct
      361 ggattccgtc cggtgcgtcc ggcttaagac agcttctgac caggtcgcct tcctccctgg
      421 ggaggcagtt cgtcatcagg gaaatggctt tgtcgcaggc atctgcctta tccatctcct
      481 ccttgcgcat ttccaggacc atctggatgg aaacctggtc attccgggaa atggcttccc
      541 ccagctcctt cgtcagaccg agtatttcgc tgatgatatt atattttctc tgaagaagcc
      601 ggattatccc cagcagaatt tcgctatact ccatattcca cccgcctaat tatacacttg
      661 cctggccgct tcacgaaacg tcccccgcag gtcttccgca aggggcttca attcctgaat
      721 aagcttccca ttccggcttg cttgtatcct ggacagctca tagaggaaga aatcgtacat
      781 gcggctgagc tgcccgctga cttcatactg gtggttcagg gtcttcttca ggtaccgtac
      841 gatttccacg gacctgttta cagactggtc aaagagctca aaattattct gctccaggga
      901 cagctccgcc cgcaggagtc ttttcaccag ttcatccagg accagaagaa gaagctcgct
      961 ttgcgtcatg gtatggacgg attgttcttt gtattgctgg tatgcctgca tattcatatt
     1021 tgttatcctt tcagtcgtgg gttttctatc agccaagggc tgaggacagc cagctgcttt
     1081 gtgaattcat ttgggaaatc agggtttcca gactggtgaa cttcttgatg tacctgtctg
     1141 tctgcagctt catctgatcc ttcagccttt caacatttct ctccgcgctg tctatctctt
     1201 tctgtatggt gttgttaagc acgctggctg gggcactggc agaacccgcc cgttgaatca
     1261 ggattccctt ggaggctccg gtggttccgg catattcctt cagaatggtg gatatttttg
     1321 ccataaggcc gcccgcttcc ccggtggttt tgttttcagt ccttgtaaag acatccttta
     1381 cggattccgg atcagactcg atcgcccgtt ttaaggccgt ctcgtccagg accagctttc
     1441 cgttgtccga gtagctggtg gaaacggaaa tccccatggt tccgagagca gccttgtccg
     1501 cgctccctga agaaaacagg aaacgaaaat catcgtacag gctgcgcagg gtgctgtcat
     1561 tgaagagaag tcctgccttg gtttttccct cccacttttc gatcttgtcg tcggtcatct
     1621 cctctttttg ggaatcggtc agaggcagat agtcccggtt tctcttagta gagagctggg
     1681 agtttaccat atcaagaatc ccattgtaat cttcgatcat ctgcttgacg gagccgacga
     1741 tttcgtccga atccacagtg gctgtgaact ggatttcctc gttatccggc acttccgtga
     1801 agacgccagc cggcgcctcc gtatatccga aggcgctttt aaccgtcaca ttcaggccgt
     1861 ccagggtaaa cgtattcgtt ccgcgtacga tatccatggt ctcattggaa ccggtatatc
     1921 ggacggtgac cagggcgtcc tgtccggaaa cagagttcat gctgccaaaa acagaggcac
     1981 tctccccgcc aatttctaca tttccgctgg ctccggacgc cgtagactta aaggtgaatt
     2041 tgtccgcatt tgccagatag ctgatttcca cgttggcacc ttcagtctta ttgatagcct
     2101 ccatgacctc cttcatggtg ctcccatagg taaggccctg gatttccacg ttgtttatgg
     2161 tcagcagcag agggtctgac tccgtttttg tccccaaacc ggcagctagt ccagactcca
     2221 gcagcgaagc ccccaggttc agccggttgg attccccggc ggatattcca agaatgccat
     2281 ccggtccaag aagacccgaa tccgcaccgg atatttccag aacggaggaa gcatcgggag
     2341 agccatccgg acgtatagcc gcaaaggaaa atgaggaata ttctcccacc gtgttcagag
     2401 aaactttgac tctgccgctt ccaaacgcac tgcccatgct tctctggacg tcttccatca
     2461 gcctgtccat ggtcgttatc tggtctgctg ccggcatagt gagctttttt gtgatcccgt
     2521 tgtaggtaaa agaaatgctc tttccggcaa gcagatcgct ggttttctcc ggatgggaaa
     2581 gaatcgcctc cgttccggta atgcccccga ctgtaatggc ggaatcggct gtaaatccca
     2641 tgtcggcaag gacactatcg ctgccgctct tcagtgccag aagattgcca tgggcatcca
     2701 attccttcag ggtgaatttt gtatcatccg ccgttaccgt cataatgtcc gccagggtaa
     2761 gccccgtacc gacgctcaca ttgctcagtg ccttatttat ggaagctgtc gcatttgcca
     2821 tgttgtcata tttatattca atcccatcca tcgtacccgt ctccagcttc actgcatagg
     2881 attcggtgcc gtatgtgaac gtcaaggtct ccccttccag attattgatc gttcgttctg
     2941 tggtcagatc ggtggctatc agccctgtcc ggagcacctg atccgaggct gccgaggccg
     3001 aagtggcgct ggcgtccatg gcaagctgtt tgacgcccgc tactgaaaaa gacgccgcac
     3061 cgctcaaccc gccggttaca gaaacacagc cactgttttt ccccacggac gcgatattgt
     3121 tcctggcaaa aaaactggcg ctggacagat tgtttttgga tgtataggaa gtatacttat
     3181 tgctgaagtt tatcatagcg gaacttatgg tccggcaggc ctccatcttc cattcgagaa
     3241 gttgcttgct ttgttcctgt ttatcaatct tcgcctggat tccgatggtc attcccttta
     3301 tcagggaatc cgtatccagt ccgctggcaa gcccgccata tcctcgtatg gtggaggctg
     3361 atgatggccc ggttgtgctg ctgatatttg acataacctt accccttttc agaatgattt
     3421 taatatatac ttatttatcg gcatatagta tacttttaat aatatttttt aagactttat
     3481 tacgaacgga ggattatttt ggcaacagtt atcgtactga caaaccaaaa agggggcgtc
     3541 ggaaaaacaa ccacatccag tgcactggcc gccggacttg ctctgcataa caatagagtt
     3601 ttggctgtag atatggatcc ccagggcaat ttaggattca gcctggggct ggacattgag
     3661 aattccagca atatttacga tgtattgacc ggaaagctcc ccatccagag caccatccag
     3721 tccacccgct actgcgatgt cataacgtcc aacatcatgc tcagcagcgc tgaaatggga
     3781 tttacaggtt ccggtcggga atcccttctg tatacagcac taaaaccgat acaggactgc
     3841 tacgattata tagtgattga tacgcctccg gcccttaaca tacttacagt gaatgcctat
     3901 acggccgcca gccatctgat tattcctatg gtaccggaga tcctaagtct tctgggtgta
     3961 tcccagttaa aagaaaccat tgcatctgta aaatccgcct ttaatcccaa cctgaatatc
     4021 ctgggtatcc ttctaaccag atacaacggc cggacccttc tggcccagga agtgaaggaa
     4081 atggctgaaa ttattgccgg gcagataagt tccattgtct ttgataccca gattcgaacc
     4141 agcgtatccg tagcggaagc gccggcgcaa ggcgaaagca tttttgatta tgcccccaga
     4201 tgcaaacctg ctgaagatta ttcttgcttt gttaaagaag ttattgcacg gataaagcgt
     4261 caggaggtgt cttaaatgcc cagaaaaagc agtaaaacaa cccatgtgct gaatctgctg
     4321 tctggctccg aggaacacga tgaatccagc ataacagatt gtgccgattc gggtgctcct
     4381 gatcagataa cagtcgtaat gccaaaaaaa tccgctgatc cggtggcgga tattataaga
     4441 gcgcggctgg aagaggaatt ctcccccaca gaattggatg agcaaccgca gcccccggag
     4501 ctggcccctg taggcgctga caagaatgaa cctttagagc aaatatctga aaagccgcag
     4561 ggcgtggatt atgcctatgt aaatgttatg gaacatatca ttcaggaaga agtagaagga
     4621 ttctgccagg aatttgaaac atgtacctgc agccgttgcc tggcagacat agccgccctg
     4681 gcgcttacca acctcccccc aaaatacata gtaaaggatt gcctgaccat ctcgcctctc
     4741 ctgaattatt acaggagcaa atattccagc caggttaccg tctctcttac caagtcttct
     4801 atgagtgtaa aggataagcc tcgtcattaa aaaagacccc tcccaagttc cggaggggtc
     4861 ttactgtttt gataaaaaca ctgctctact gactaaccga tggcttccat gaactgggac
     4921 gcaatgaccg gatcaaactg agtccctttg catctttcaa tttcttcaaa tgcttcctca
     4981 aaagtctttg tttcctggta tgttctatgg tttgtcatcg catcaaagct gtcaataact
     5041 gtcagtatcc tggccagata ggaaatctct ccccccttta aaccctgtgg gtaaccagtg
     5101 ccgtcaaact tttcatgatg ctgcagaaca ataggcacca cctcttccag cccctcaatc
     5161 tgctcgataa tggccgcact atccaccgga tgtttccgca gttcttccca ctgttccggg
     5221 gtcaggttat tatctgctac aagcacttcc ttggaaacat ttattttccc aaggtcatgg
     5281 agataggccg cgtaaagtag ttttttcttt tcatggtccg caagtttaag atgattggcc
     5341 atgatttcac tgtaattata gacccggtcg acatgattga acgtatagga gtcccttgaa
     5401 tttattactg taatcagagt ttttagaggt ttcatgacct ccgttagtcc atcgccccca
     5461 cttgaacctg tctgatcaaa tatagaagaa tagacttcca ctttatttct tcttaaaaat
     5521 ttagccctat acaaagccct gtctgcttct gcaataaaat cgttgtaatt ctccgtttcc
     5581 tcggtaaggg aggccacccc gacagatact gtcatcttcc ggttgggcag gtattcttga
     5641 cccggaaacc cataaatgga gacagcattt cgcagattat ctgcaacttg ggccgcttca
     5701 tcctggcaaa tgcctggcat caacacgcaa aattcatccc ctccgtaacg aaagagaatg
     5761 tcctcctgtc taaggcacat tttcaaaact tcgcttattt ccttcaggag ctcatctccc
     5821 ttattgtgtc cgttcatatc gttatatttt ttaaaataat ccaaatcaat cattacaagt
     5881 gaaagcgctg catcatgctg gatactttca tcatacatta tgcttatcat gtcataaaaa
     5941 catctgtgat tataggcccc agtcagtcca tctatgttag catattcggt cagttcatca
     6001 atatgcgact tttccagttt tacgtaatag cccaatgtcc atgccaccag gaaaaacatt
     6061 actataagtg caatgtcatc ttcaaaatag cggtttacgc ctcttgtccc tcccatcaaa
     6121 atatccataa gtatcacagc acccgaggct atcgaagcaa tgattaaacc caacttcatt
     6181 ccatgttcaa tggtaaagga aacgattaca aagaggaaaa tgaatttgta ataactttca
     6241 ttcgcaccgc taacaacaat tacggtaata aatacggcta aaaatataac gacttccaaa
     6301 acctgcagaa atttgttctt ttcactccgg ttaaagacaa aaaacaaaaa aaacattaca
     6361 agacagatta caatcaatgt caaaccaatc gcataaacac tataattatt attaacaaaa
     6421 tctatattga gctttgctga aaaatattga aacaggggga ttgcagaaaa gaacagggca
     6481 agcatcttaa aagtaaaaaa cattgtcctg atttgtccct gcttcgcctc tccaagattt
     6541 gagatgcttt tttccatgaa ttaagtacct ctcttacgaa atttcagtta atcgttgtaa
     6601 tactaaaaat cagagacttg caaaaatttc gtttcgcaag cctctttgcc ctgttatcta
     6661 tcgttgaggc attttggttc ttctggctga taaaaatacc agaaacatgc tgatgttgca
     6721 atcgtaccag caaacagtgt tgcaagagca gtaacggctg caagtattct tgtctttttc
     6781 atttgaaatc cccctttcaa atttattcta taagattatt atcctatatt tttagttaag
     6841 cagaaactcc cctaaacccg acatcaatcc aggcaaaaaa tacctgcccc agccttgtca
     6901 gggtgagcgc ttgccaaagc atcgtcagcc tgataataac cgccagacta aaaaaacgtg
     6961 tattccatcc agtcagaaaa acacaaacca tggatagcaa aaaaaatgca gtcaatatca
     7021 ggaagctttg ttttcgtaat cttttaattt tttcgggttt aacaattggt ttgttaggag
     7081 tatcaactgg aacccggaga taaaaaacaa caaaacatag caagtatata aaaatggata
     7141 cgaaacaatt cagataaata tttatgctta tgtcaaaaat atatctggcc gccgcagaca
     7201 gcaggctaat cgaagatacg ctaataagga tacaccctag cattgtggcc gaatgggcac
     7261 cacccgtaga ttttcttatt attcctactc ccagaaaaat cacaacactt tccatccaaa
     7321 agccaaaaaa tagtccaaat attgagatga tgacaaagat tgtagccatc tgaatcattg
     7381 cagtcaaacc ataggcaatt actgcttttt tatcttcatc atacttcatt tgcaaactaa
     7441 ttctttcagc agttctcttc gcccatcttt ccatcgatgc cattccttcc cctcaatcga
     7501 taattcgaga aataataagc caggataatt aatactgcaa agaataatgc gccaggcaaa
     7561 ccaataatgg cccggtttga agaaaaaagc atctggtttt cgaatttcgc tttcccaatg
     7621 atagaaatca cgactgccac gtttgccatt tcgctgacca ataatattac tgtaaccaac
     7681 aacgcagagc ggattgttga gaatccaggc attttcaaga acatgataca tatcagaaaa
     7741 agaaacaaca tattcagtat ggtatgtaca ccgaagctaa ttggaagcat tctcaccaga
     7801 aaagatacga tgatagtcaa aagacttgtg aggacataac ttttcacctc aattcttttc
     7861 cggttaaatg catatattcc cagaacgatt ataaatccct gcaaagcata tcccaacagg
     7921 tattcaaaca gtataatttt aaataattcc atatattttc tctctttcca attttttgtt
     7981 cagttcttta atcgaataat agactgtgat gaatacaaaa gaatgtatca gcagatcacc
     8041 aatgctcata atgctgtaac ccacatcgat ataatctgtc aggaatttga atctgacaga
     8101 ctcgttgcca agtatatgta tgctatctgc tgtttgaata gcagatgcat caaaatatcc
     8161 ggtgattttg gaaagtgaag gatagaccgg catttttcct ccattttgga tcatgacaaa
     8221 tttattcaga aaagtgccag caattatcag gccggcgcct aaaagcccct gtttgtataa
     8281 tttaaaaaac ataatcggaa ttatcaacgc gaacagaaag atattgttca gaatggcgga
     8341 atacattata aaatcatagt ttcccataaa tacactgcct tgcaaaaaaa tatatagtaa
     8401 ttcaatagca aaatatgggt ataacacata ggccttcata agcggccgca gtctgtaccc
     8461 tttcaatttc ccacacaaaa aagctaacag caaaaacact aacatgatgt cttccttttc
     8521 cattaaactt tatgtcacga tagatttaaa tgattataac ataggttgtt caccgcttcc
     8581 acatttattt gtgcatagtt cctgtttttg ccgacaaatt aatatttttc gctccatttt
     8641 tcgtattctt tggatgccat ttgctgggaa tcaacacgaa gatcgttaat ttcctggaaa
     8701 ttatctatga gcaattttac aattctgccg tctaatgcac catcttcagc ctggtttatc
     8761 agcaacgttg cagccttatc gtcacgcatt ccctcccggt agggccggtt ttctgtcaca
     8821 gcagtaaata catctgccac ggccattacc cgagatccga gagccagatt ctctcccggg
     8881 atatgaaaag gatacccttt cccatccagc ctctcgtgat gataggacgc ccagacatta
     8941 attgtgttga attgaggtat ggtttccaga agacggtaag tataatatgc atgggaacgg
     9001 atttcattga attcatcttc attaagactg gtcggttttt caagaacatc attatctatg
     9061 gctaatttcc caatatcatg cagatagcct gctacaagga gcatcttgca ttccatgggt
     9121 gagaaaccga tcagctcgcc cagtttttca gctgtttttg ccactccggc tgaatgtctt
     9181 gccgtgaact tactcctgaa atcgattata tgggaaaaca cttttgccag gctgataata
     9241 tcccccatct ccaaaataaa ttttttgtta tctcccagtg ggagcgtatt taccggcgat
     9301 acggacatga tatccagcca tatatattcc tttttgctta tagcctcgag agcatccacc
     9361 accgcaggca taaaccggct gttctcttct ttccgaattt ctgcaagaac tccgggaagc
     9421 tgggacaaaa tattttcgga cttattgatt ttcaaacagg ttctgtccgc caagtgtatg
     9481 atatggctgc cgaacgggac ctcctgcccc ttgaactgtc gtccggttcc gctatcccag
     9541 ggcaaatgat gataccttac tatattggca ggttttccca tggggctgaa tttttccata
     9601 agcctggctc ctctgaaagc atgatcacaa attccagccg gttcgtccat ggagatcctg
     9661 cgtctttctt ccgttgaaag aacacccaga tcatgaatca gggaggccag aaatatctca
     9721 cttttttcct gatttgaaag tcgtagctcc tcagccagat gataggaaag acaagctacc
     9781 tcctgctgat gattgacggc accgtcagcc gccaggtcct gtgcattgga aaggcacaac
     9841 aacagctcat ataggttcac tctgattttg tccatctatt tattctcctt actccacggc
     9901 caattacgta aaagcaatat ccagaaccat catcagcaca aacccggcca tagcccccaa
     9961 tgtaccaata ttggaatgtt tgctgtaagc ttccggaacc agttcgtcca caaccacata
    10021 aatcatggct ccggccgcaa aggaaagcat aaagggcata atattgacaa cagcaaccgc
    10081 cagcagtacg cccaaaagac cggccattgg ttccacaatt cccgaagcag ctccaaacag
    10141 aaaggatttt tgcttggaaa agccctctcc tctcagcggc agggaaatgg ccgctccttc
    10201 tggcagattc tggagagcca tacctgtggc caggacaaac gctccggtaa gtgctgcaga
    10261 tgatttcgaa gccattgcaa aggccagacc caccgccata ccctccggga tgttatgcag
    10321 agtcacagcc agtacaagca gtgtggaccg gggcatcttg cttttaattc cttccggacg
    10381 ttcagcatct gcatgaagat gaggcagaaa tttatccagc aggaagagga aaatcccccc
    10441 tgaaataaat ccaagggcag ctggcagcca ttcgatgtcg cccttttcct ttgacatttc
    10501 aatagctgga agtaataaag accagacgga ggccgcaatc atgacccctg atgcaaatcc
    10561 cagaaaggtc ttttgcactt tccctcctgc ttctgccgcc acgaaaaata cggtcgcagc
    10621 tccaataacc gtggccagaa acgtgatgcc cgttccaatc aaagcaagta ctaccggtga
    10681 attgatttcc tccatccttg tgtcctcttt cttaaagcaa taattccctg atttctttcc
    10741 gtgtatccgg atgctcacgc tcctgcagat ccggttcaag gtcttccttc agtccatgct
    10801 ttccaacggc aatcacggta ataatatcgt actcctgcgg aatattgaat atgtcccggg
    10861 cttcctccct tttgaaccca gccatcggat gagccaccag gcccctcctc caagcctcca
    10921 aggaaagata cccccaggct gtccctgcat cgaacatatg ccagtaattg tctttaccat
    10981 tatggttgaa agtctttttg gatacaataa ggatcagaac aggagcctta tttgcccatc
    11041 tctggttgga ttcagtcaat atccctctca tccggtcaag tgatccctcc tcatcagcca
    11101 gtacgaacct ccaaggctgt tcgttaaagc aggaaggagc atacctcgcc gcctccagga
    11161 gggcaaagac ttcctccctg tcgattcttc ccggagccag agccctggca gaccaccttt
    11221 ctttgatttc agtcatgatg tcgtaatcaa agtgtctttc catgtttttc cccctaatat
    11281 tcttctctca gtccaaactc agcgttttct acccactctt ccgcattggt cagcatcctg
    11341 tcaatctcat ccagtattga aaaatggagt ttctcctgat tgatcaaaaa tctgaacagt
    11401 tccttttcgt catcactttg ggcatttttt agaaattccg tgtaaagatc gatgctcttt
    11461 ttttcaaatt ccagtcctgc cctgtaaaaa tcaacctgac tgggaatcaa tttcccaaga
    11521 attctcacat caacggccga ttcgaacaca ttcatgattt cagtaaaagt atcccgatca
    11581 tccagttggt aggcttttcc ttcaagcctg gctttcagta aactggcatg cttcttttct
    11641 tcctccgcaa gcttggcgca gacgacgcac atcccattgc cttcatggag ttcggcctgt
    11701 tccatgtagt acttcgctcc gtcctcttcc atcttaatcg caaattccaa actgttcata
    11761 tgcattctcc ttttcttttt actgctgata gtaaaccgat atggcaatca tcagctgtcc
    11821 taaaaagtaa cataccgcaa ctagtgttga aaaaatccgc ctctttttga taaacctgtt
    11881 tataccaaga aacatatctg aaacccagaa taataatgcc cccatcgaga acatccactg
    11941 cagggtcatc accctttctc ctgccagcaa catcatgacc gcttttgccg ccataagagt
    12001 taccagagcc gtataaatgt taatcggaag tcttgccttt ccaaaatccg gcttcatttt
    12061 caataccaca atcaggatgg ctgacagcac gagaatcgtc atgatgaatt ctccgattcc
    12121 gatccctgaa agaactatca ttccggcaat ataaaatacc tgcgtgacag aaaaagcaag
    12181 tatcccacaa atgaatcttt tttcgtccgc aaataggaac accagaaagt aatccccaat
    12241 catagccaga atcaatccac ccagaatcag cagtgggaaa atgctgaaat catgaacgaa
    12301 gactgccgcc aatcccaaaa cgcagaatat acctgaaagt acaagcttat atccaggtgt
    12361 ctccaccgat tcccttttcc tgtccatcca gatgtaaata ggaagaagaa caagcagata
    12421 taggacacag attatagccg ttaccaggat tcttaaatcc atttgcaaca ccccctatag
    12481 tattcgctcc ggactggtgt atatgttaat gtgatccttt cggacaaatc ccatcattgt
    12541 aatcttattc atttccgcaa ggtggacggc tgccagtgtg ggagctcccg gtgccaccaa
    12601 taccttcacg ccacaggaaa gtattttccc gatcatatcc tgagccagcc ggccgctgaa
    12661 tatcagcatc tttccttccg gggtcagacc ctgcaggaac atctccccta taaccttgtc
    12721 caatgcatta tgccgtgcca catcttccat gaagatcagg ataccatccc tgtctgccag
    12781 agctacactg tgtgctgcac ccgttttgtg gaacaggtag cactttctat taaacgcctg
    12841 atttaagcgg tgcacatcat ctgggctgaa cactgcattt atctcttttc tggatttttc
    12901 ctccgccgca ggggatgtcc tgagacaaag accccttgcg tcctcatcca ccatgaattc
    12961 ggcaacctca tcctgcattc ctatcagccc tttggcaagg ccgtgtccgc aggcaagctg
    13021 aagcaaatta tccggaagac agaaaaattc tccgcagttt acgccgttaa tttccatcgt
    13081 atatctctct tccaaaagga tgcagtcttc cgcacagaat ctgccctgtg gggttattct
    13141 ggtaatctgt ctcattttta tcgaattctc atatttttta ttttgcatct ttctccgtat
    13201 ccttatccag tcatttcatt gaagcaaatc caatgtcctg gcctcgtttt ctaaattttc
    13261 aaaaaaactt gcgatatgct ttccatccgc cagcgcgtga ttcaccagaa gagtcgtggg
    13321 catcagaacc cgaccatctt gaataaaaaa acggccaaag gtaatgcgcg ggttgctgtc
    13381 tgccgggtag ggggtcggct gggtaaggcc ggtatagctc acccagggta cagaggatac
    13441 aaaatagagg gaacccgttt ccgttacatc ttctatactg ggatcctgta tcgccagtga
    13501 ctgtcttttt cccgcatcct ccagaaaatc cttaaagggc atgttgaaat ccaaacggca
    13561 atgacagtat gtcccgtctt ccagagccac tgtgtaggag gctccacaat gttcgtattc
    13621 aatgatttcg tccccctcaa tcctctgacg aagctgtgga atctgattgg ccgcagaaac
    13681 ggccaggtaa ataattgtat gaaaaaatgc atattttctg gatttgattt ccgcaagcag
    13741 ctccgtgata tcaacgttgg ccgtcactcc tgcgtatggg ttgtgaaggg agcggaaata
    13801 ttcaaaatgt ttgatgcgcg gataagaatc catgtccagc cttttgattt tcatcgtagc
    13861 ctcctgattt tacttctcgt cacatacctg gaaaatatag aatttcagat aataggattc
    13921 atccgcagcc cagagtatcg gatgatccgg tgcctgagta cggtattcca cctggcgcag
    13981 ccttttatgg acgtttcgcg aagcctggtg cagagtctgt gtaaagagct catatgtcat
    14041 gaaatgggaa caggaacagg ttgccagaaa tcctccatct ttaagcagtt tcatggcacg
    14101 aaggttgatt tccctgtaac ctttgatggc gttcttaacg gaatttctgg atttggtaaa
    14161 ggctggggga tcgaggatta tgacatcgaa cttttcacct ttttcttcca tttcgggtaa
    14221 taattcaaaa acatttgcac actgaaaatg cacgatattc tccaggccgt tcaatttagc
    14281 attctctctt gcctgggcga ttcccagttc cgaagcatct atccccaata cgcttcccgc
    14341 ctcagctaac cccgcattta aagcaaagga tcccgtatga gtgaaacaat ccaggacctt
    14401 ggcacctttg cagagtcttc cgacagccag ccggttatat ttctgatcca ggaaaaatcc
    14461 ggttttctga ccttccttta catccacaat atatcgtacc ccgttctctg taatctcaac
    14521 attcgtgtca aactccggtc cgataaatcc cttgaatcgc tccattccct cgttttccct
    14581 taccttggca tcgctgcgct caaatattcc ccggatctgt attccgtctg cttccaatat
    14641 cgacctcaga catttcagaa tggtgtcctt tagccggtcg attcccaaag ccagggattc
    14701 aacaaccaat acatccgaaa atttatcgac aatcagaccc ggcagaaaat ccgcctctcc
    14761 aaaaataatc cggcagctgg atgtatccac tgttttctta cggtaatccc aggcgttctg
    14821 cacacgcatg cgcaaaaagg cttcatcaat ttcctgctcc ttgtttctgg tcatcatgcg
    14881 gatgcggatt tttgaatttg aatttataaa gcctttcccc ataggaaatc cgtcaaagtc
    14941 atgcacctga actatatctc cgtcttcaaa gcttcccagg actgtctcta tctcattgtc
    15001 aaaaacccac atccctccgg ctttgatggt tcggccttca ccttttttca atgttgcgat
    15061 tgtcatatat tttcctcatt ttctcatttt attattttac aaaatagtcg tccaacccgg
    15121 cagtgatccc ctctgcgatc tcatattgat atgcctgggt cgaaaggagc atatcctctg
    15181 tctgattggt catgtacccc atttcaatga ttgtggccgg tacctggcac cagttgatgc
    15241 cgctcattgt atctgtctcc cagacgcctt tgtctccggc tccggttgaa taaagcacca
    15301 tgttcaatat gcattcagaa agtctgcggc actccccgta aagattcccg caataagggt
    15361 tggagggggt agggcaaatc atcatgactc cgttcgtttc tggattctca ctgccattgg
    15421 catgaatccg tacaaaggca tcggcaccat tattgttggc ggcttccgcc ctctgggcat
    15481 tgctgatatc cacatcattt gtttcacgaa tcataataac ctggtagcct ctggctaaaa
    15541 ggagagcttt cagtttcaga gccacctgca ggttcagttc atattccggc agtccggaga
    15601 atctgcctgt cgtccctgag gacactttgg ccttcgtctg ggaagctccg gggccaatcg
    15661 gttccggttc gctgtcacca tgcctttgat gtcccgcatc aatagccacc acgatacctc
    15721 ctgcttccac ttccggactg cgacctgaag attccggcga tgcagtctgg gtgtccacgg
    15781 ctggatcctg cggaccggtc tccgggggca tcgtgttagt ttccgcagga atcccggaag
    15841 tctcctgtgt catactttct atgatattgg gaacggtatt ttcagtagtt ccttctttct
    15901 ttgcggcgct gcaggaaaga agctgcagca aaatccccgc gaacatgatg cacacagcta
    15961 tttttttcac accaatccct ccaatcatta tatcatacaa ctttatacat aataaaggtt
    16021 ttcagaagga tatactggat cacacgtaac atcgattccc agctggcgca gaatctgttc
    16081 agcctcattg ttcagcatga ccgttgaatg ggcctgtaca tccttgagtc cggacagctt
    16141 ttcataggct aattttgctg tcggattgat tacagcagaa atactcaggg ctataagcac
    16201 ctcattggca ttcagggcgg aaaccctgct gtggaggtct tctgtcttca gtttctgtat
    16261 ggtttccaga acagcagggg acaggagcgg aatctcatcc gcaatgtttg ccaggacctt
    16321 aatggaattc agaatagccg ctgaacagga gtccataagg caggaggacc gaccggtaat
    16381 aaccctgcca tccggcattt caaatgcaat gacggaaacc gagtcctggt tttcagattt
    16441 tgccttcaac ctctccgcat actggcgggc agggagcacc gccacccggt ccgtcttctt
    16501 cagcgcaagc tcttccatga taattctcat ccgattgagc acctcttcat ccaacaatcc
    16561 ttttttaaaa tcacattctg tggaaaagct cctccggatt atttcctgcc gggatgcatc
    16621 ctttatcact tcgtcatcgg taatcccaaa tccgacacgg tttactccca tatctgtcgg
    16681 ggactggtac atggattctt tccccgtaat tttctcgatg attcttttaa tgaccgggaa
    16741 catttccaga tcccggttgt aattgaccgc cacttcatta tatttttcga aatggaaata
    16801 atccagcata ttgacgtctt tcaaatccac tgtggctgcc tcataggcga tgttcagcgg
    16861 atgtttcagc gaaatgttcc aaaccggaaa ggtctcgaac ttggagtagc ctgctgcgtt
    16921 tccaagacgg tgttcatggt acagctggtt cagacatgtg gccagtttcc cgcttccggg
    16981 accgggtgcc gtaaccacca caatcggttt ggtggtagca atataaggat tcttaccata
    17041 tccctcctca cttacaatag catccacatc tgaaggatat ccttctatag ccacatgtgt
    17101 ataaaccttt atcccccttc tctccagctt ggtgatgaaa cgttttgcag atggctgacc
    17161 ttcgtaacgg gtaatgacga cgctgttgac ctccagttcg tattccctca aatcgtctat
    17221 cagtttcatg acatccatgt cgtaagggat gccgaagtcc ccgcggattt tgttgcgttc
    17281 aatatcccct gcataaacac agataacgat ttccgctttt tcccgcagct tatataaaag
    17341 cttgattttc gcatcctcat caaatccagg cagcactctc ttggcatgct tgtcgcctat
    17401 gagctttccg ccaaactcca gatacagctt atcgaattta tttacccttt ccagaatata
    17461 ctttgactgt tcct
//
