LOCUS       NC_008639.1            10996 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NC_008639.1 Chlorobium phaeobacteroides DSM 266, complete sequence.
ACCESSION   NC_008639
VERSION     NC_008639.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 12:55:13
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2051688
            Orig. end    :: 2062684
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10996
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[2056688:2057684](-)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5996)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     cand_cluster    1..10996
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10996
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="butyrolactone"
                     /region_number="5"
                     /rules="AfsA"
                     /tool="antismash"
     CDS             complement(770..1528)
                     /locus_tag="ctg1_1891"
                     /transl_table=11
                     /translation="MGIFDRFFKKESNAPAIVSRELRKPDMTSLFEGISTWSTGKRFRE
                     ADPGYSEMIRSLPPDQASSMRLSRVSGTISITGESPTVFGYPGSLELNMPALTSLSGMA
                     RVLLDLGYAGVEDEAGAITESIMNRTFRFRISFFAEQHYPLVRLQVGFYNGLQEPLFLE
                     VLSDILDLNVQDFYASLIEKGRYEISVHAGREHLASVFCTISDSDLLPVAEGLNMMVAH
                     LKNITSSGWNMQKAVRSFERHHPLGEGMGR"
     CDS             complement(1583..3682)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 96.1; E-value: 3.8e-29)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg1_1892"
                     /transl_table=11
                     /translation="VLAYIRQCVIDGTQVSRFNTLAAGLLGAPAHFFFYFIFKYGFDLP
                     YENLFLRLTATLLCLAVLFKSRLPGFIQTRFTFFWHFTIIFVLPFVFTVNLIMNNFHEL
                     WLYWEIFMLFVLIAFVPNWLMFLFDLLLGFAGAVVFYFLSTPRVELHPEFNIPLYLLVL
                     VFTIVAGYVFSYSNKRGIMAMERNNALKALAAGIAHEMRNPLGQIRYNLESIQEELPLY
                     HAERLYPSISAGGVERIYEKVARGQIAVNRGIQVIEMILEEVREDASEDAGLTYLSAAA
                     ITRKAIDEYGYESQEERQRVHFFEDDDFVFKGVETMYVFVLFNLVMNALYFLRSFPDGR
                     IDIRLKRGEILNSVTVRDTGPGVAKENLAKLFDPFYTSGRKGGTGLGLAYCKRVMRFFG
                     GDIVCRSVRYEFTEFILTFPPVSDGDIADFEADLYAQYHELFSAKRILHVGADPANLVL
                     IARYLLPLSVELDQVQSGAEAMEMIASRQYDLVLLDLELPIIDGYELAFRMQENGVVLS
                     IVAYTRMSSTLLKGRAEKLGIQALLSMPIVLAELLSVLAEAIETKPDTLKNSLAGKTVL
                     VADDSALNRMVVKNILQRGGLTVLDAKNGQEAIDILEHYPCDLLLIDIQMPVLDGLEAA
                     KRIRATKSGYRGIPIICLSGDGDKETVRRAMESGMNDYLIKPVDSKNLLQKVSRLLLLT
                     EKTQK"
     PFAM_domain     complement(1622..1960)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1892_0152"
                     /evalue="1.50E-27"
                     /label="ctg1_1892"
                     /locus_tag="ctg1_1892"
                     /protein_end="687"
                     /protein_start="574"
                     /score="96.1"
                     /tool="antismash"
                     /translation="VLVADDSALNRMVVKNILQRGGLTVLDAKNGQEAIDILEHYPCDL
                     LLIDIQMPVLDGLEAAKRIRATKSGYRGIPIICLSGDGDKETVRRAMESGMNDYLIKPV
                     DSKNLLQKV"
     PFAM_domain     complement(2021..2338)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1892_0151"
                     /evalue="1.10E-12"
                     /label="ctg1_1892"
                     /locus_tag="ctg1_1892"
                     /protein_end="554"
                     /protein_start="448"
                     /score="48.2"
                     /tool="antismash"
                     /translation="VGADPANLVLIARYLLPLSVELDQVQSGAEAMEMIASRQYDLVLL
                     DLELPIIDGYELAFRMQENGVVLSIVAYTRMSSTLLKGRAEKLGIQALLSMPIVLAELL
                     SV"
     PFAM_domain     complement(2423..2722)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1892_0150"
                     /evalue="6.90E-17"
                     /label="ctg1_1892"
                     /locus_tag="ctg1_1892"
                     /protein_end="420"
                     /protein_start="320"
                     /score="62.1"
                     /tool="antismash"
                     /translation="VLFNLVMNALYFLRSFPDGRIDIRLKRGEILNSVTVRDTGPGVAK
                     ENLAKLFDPFYTSGRKGGTGLGLAYCKRVMRFFGGDIVCRSVRYEFTEFILTFPP"
     PFAM_domain     complement(2879..3115)
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1892_0149"
                     /evalue="2.40E-06"
                     /label="ctg1_1892"
                     /locus_tag="ctg1_1892"
                     /protein_end="268"
                     /protein_start="189"
                     /score="27.6"
                     /tool="antismash"
                     /translation="LKALAAGIAHEMRNPLGQIRYNLESIQEELPLYHAERLYPSISAG
                     GVERIYEKVARGQIAVNRGIQVIEMILEEVREDA"
     CDS             complement(3685..5004)
                     /locus_tag="ctg1_1893"
                     /transl_table=11
                     /translation="MMRAAVIGGGISGIASAYYLMQHNISVDLYESADRIGGRIGSERL
                     GERWLDFGGKNIGKNYRLFRDFVLDCGVSDFEYFGFNTSQVIGGRVVSINKEGARLFNA
                     IRFFGLCGFSGLRKLYPHVRAILNDRRQGVLASEYFSALAEEYDHLSLAGYLKEPCLSH
                     IVRPVTVRMNGAEPDECYPGNFGSNLALLLDSYEQLQQGMHGMLEAFQLPARSALLRIL
                     PAHRVTSVNRDHGKGAVMIGYEYEGRSLSAEYDRVVSALPALRLSELLETFCPEVSVLL
                     RRIQYFPVAVAIVKYRQNVFPKEQRAMVFDDSFPLSNAGAYGINDLDLVRYTFSGRAAR
                     AMVSDRSQPEAVITLGEEIAGRYFTIKDNTRESFVFRYLSEGLCAYSPYHHRLLAEVDQ
                     KLDFFSGFAATGDYRRGASIEACFRAAGECVHKLLDGGKD"
     PFAM_domain     complement(4078..4974)
                     /aSDomain="Amino_oxidase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01593.26"
                     /description="Flavin containing amine oxidoreductase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1893_0153"
                     /evalue="1.30E-18"
                     /label="ctg1_1893"
                     /locus_tag="ctg1_1893"
                     /protein_end="309"
                     /protein_start="10"
                     /score="67.6"
                     /tool="antismash"
                     /translation="ISGIASAYYLMQHNISVDLYESADRIGGRIGSERLGERWLDFGGK
                     NIGKNYRLFRDFVLDCGVSDFEYFGFNTSQVIGGRVVSINKEGARLFNAIRFFGLCGFS
                     GLRKLYPHVRAILNDRRQGVLASEYFSALAEEYDHLSLAGYLKEPCLSHIVRPVTVRMN
                     GAEPDECYPGNFGSNLALLLDSYEQLQQGMHGMLEAFQLPARSALLRILPAHRVTSVNR
                     DHGKGAVMIGYEYEGRSLSAEYDRVVSALPALRLSELLETFCPEVSVLLRRIQYFPVAV
                     AIVKYRQNVFPKEQRAMV"
     CDS             complement(5001..5996)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1894"
                     /sec_met_domain="AfsA (E-value: 2.5e-22, bitscore: 76.2,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQQTVQRIAGHDFHPAFHPNPTPRLRFQRTIKRPGRDFGILTLS
                     PGKKPFTMLLEGDTLPLQSVTALQIVNVSSVEEASRFLLLLGDTCELFISLDYRRANPG
                     VYAAAKALYCPSRKDKPPFDIETAADLMKKLPFDLKSLLKSPLAITGDDKLPCSIEKKY
                     VHKKNSSNVLISDYFSAGRMLYFNMLASTEEISFDHVSDHVQGLLMLEALRQAGVATAH
                     IQGLSFDGGLALLNYNTNFFHYLENDVPVVLRVYCSFTADETSEDKDAPIYIQVLQYGR
                     VVADATLKAFAFMSSKRYEEQRKRVEKICTRSKMQFDAKINRILHEAASV"
     PFAM_domain     complement(5124..5510)
                     /aSDomain="AfsA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03756.15"
                     /description="A-factor biosynthesis hotdog domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1894_0154"
                     /evalue="1.40E-43"
                     /label="ctg1_1894"
                     /locus_tag="ctg1_1894"
                     /protein_end="291"
                     /protein_start="162"
                     /score="148.1"
                     /tool="antismash"
                     /translation="YVHKKNSSNVLISDYFSAGRMLYFNMLASTEEISFDHVSDHVQGL
                     LMLEALRQAGVATAHIQGLSFDGGLALLNYNTNFFHYLENDVPVVLRVYCSFTADETSE
                     DKDAPIYIQVLQYGRVVADATLKAF"
     CDS             6328..7314
                     /locus_tag="ctg1_1895"
                     /transl_table=11
                     /translation="MSQLDLLNIVHRPRRLRKTAAIRNLVQEHTLSVNDLVFPLFVCPG
                     TSVVEEVSSMPGSFRYSIDNAVKECQELWDLGIQSIDLFGIPEQKTEDGSEAYNDKGII
                     QEAIRAIKAKLPDLCIMTDVALDPFTPFGHDGLVKDGIILNDETVEVLCKMAVSHANAG
                     ADFVSPSDMMDGRIGAIRESLDDAGSSDVGILSYAAKYASSFYGPFRDALHSAPQFGDK
                     STYQMNPGNSDEAMKEIELDIMEGADIVMVKPGLAYLDIVSRTKERFDVPVAIYHVSGE
                     YSMVKAAAARGWIDEERVMMESLLCMKRAGGDLIFTYYAKEAAKKLR"
     PFAM_domain     6358..7302
                     /aSDomain="ALAD"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00490.23"
                     /description="Delta-aminolevulinic acid dehydratase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1895_0155"
                     /evalue="3.00E-147"
                     /label="ctg1_1895"
                     /locus_tag="ctg1_1895"
                     /protein_end="325"
                     /protein_start="10"
                     /score="489.9"
                     /tool="antismash"
                     /translation="HRPRRLRKTAAIRNLVQEHTLSVNDLVFPLFVCPGTSVVEEVSSM
                     PGSFRYSIDNAVKECQELWDLGIQSIDLFGIPEQKTEDGSEAYNDKGIIQEAIRAIKAK
                     LPDLCIMTDVALDPFTPFGHDGLVKDGIILNDETVEVLCKMAVSHANAGADFVSPSDMM
                     DGRIGAIRESLDDAGSSDVGILSYAAKYASSFYGPFRDALHSAPQFGDKSTYQMNPGNS
                     DEAMKEIELDIMEGADIVMVKPGLAYLDIVSRTKERFDVPVAIYHVSGEYSMVKAAAAR
                     GWIDEERVMMESLLCMKRAGGDLIFTYYAKEAAK"
     CDS             7392..8585
                     /locus_tag="ctg1_1896"
                     /transl_table=11
                     /translation="MIRYLTSGESHGPALSAIVEGVPAGVGITPEMINTELARRQQGYG
                     RGGRMKIETDQAEVLSGIRFGKTIGSPITLIIRNRDWENWTTTMSQFSEPAEDIAKITI
                     PRPGHADLTGKIKYGLNDIRPVIERSSARETTARVAAGTISRIFLKAIGIEIGSYISAI
                     GSAGETTADTQIEKLLRSGAETLARKADRSAVRMLDKKKEAEAIIAIDAAKDAGDTLGG
                     IIEIFITGVPMGLGSYMQHDRRLDANLAAALISIQAIKGVEIGTAFANALKPGSQVHDE
                     FIIEPEKGLTRSSNRAGGIEGSMSSGQTIHLRAAMKPISSLLTPLHSFDSETLQPTLSR
                     FERSDTCAVPAAGVVAEAMVSTVIANAVLEKFGGDHLGEIQTRISLHRDLTRKAFIA"
     PFAM_domain     7398..8498
                     /aSDomain="Chorismate_synt"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01264.23"
                     /description="Chorismate synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1896_0156"
                     /evalue="2.20E-113"
                     /label="ctg1_1896"
                     /locus_tag="ctg1_1896"
                     /protein_end="369"
                     /protein_start="2"
                     /score="378.4"
                     /tool="antismash"
                     /translation="RYLTSGESHGPALSAIVEGVPAGVGITPEMINTELARRQQGYGRG
                     GRMKIETDQAEVLSGIRFGKTIGSPITLIIRNRDWENWTTTMSQFSEPAEDIAKITIPR
                     PGHADLTGKIKYGLNDIRPVIERSSARETTARVAAGTISRIFLKAIGIEIGSYISAIGS
                     AGETTADTQIEKLLRSGAETLARKADRSAVRMLDKKKEAEAIIAIDAAKDAGDTLGGII
                     EIFITGVPMGLGSYMQHDRRLDANLAAALISIQAIKGVEIGTAFANALKPGSQVHDEFI
                     IEPEKGLTRSSNRAGGIEGSMSSGQTIHLRAAMKPISSLLTPLHSFDSETLQPTLSRFE
                     RSDTCAVPAAGVVAEAMVSTVIANAVL"
     aSDomain        7398..8513
                     /aSDomain="TIGR00033"
                     /aSTool="tigrfam"
                     /description="aroC: chorismate synthase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1896_0036"
                     /evalue="9.00E-117"
                     /identifier="TIGR00033"
                     /label="ctg1_1896"
                     /locus_tag="ctg1_1896"
                     /protein_end="374"
                     /protein_start="2"
                     /score="387.9"
                     /tool="antismash"
                     /translation="RYLTSGESHGPALSAIVEGVPAGVGITPEMINTELARRQQGYGRG
                     GRMKIETDQAEVLSGIRFGKTIGSPITLIIRNRDWENWTTTMSQFSEPAEDIAKITIPR
                     PGHADLTGKIKYGLNDIRPVIERSSARETTARVAAGTISRIFLKAIGIEIGSYISAIGS
                     AGETTADTQIEKLLRSGAETLARKADRSAVRMLDKKKEAEAIIAIDAAKDAGDTLGGII
                     EIFITGVPMGLGSYMQHDRRLDANLAAALISIQAIKGVEIGTAFANALKPGSQVHDEFI
                     IEPEKGLTRSSNRAGGIEGSMSSGQTIHLRAAMKPISSLLTPLHSFDSETLQPTLSRFE
                     RSDTCAVPAAGVVAEAMVSTVIANAVLEKFGG"
     CDS             complement(8592..9401)
                     /locus_tag="ctg1_1897"
                     /transl_table=11
                     /translation="MMRDIPIESIWSTIVAEAAAECLRDPEISIFLEQHIIRYDNFGAS
                     LAMLLSVKLGSKHFPPLVLQGLFEDFYRHCPEQVENAIYDLLATQQRDPAAVHYFEIML
                     FLKGYQALQAYRLSHWLWKNGRRTMAYFIQNRMSEVFAVDIHPAAVIGKGILLDHATSL
                     VIGETAVVDDNVSLLHEVTLGGTGKESGDRHPKVHKSVLIGAGAKILGNVIIGEGSKVG
                     AGSVVLDDVPPHYTVAGVPAQIVGKTEVPEPSRDMNQRLVGSPSEGS"
     aSDomain        complement(8673..9152)
                     /aSDomain="TIGR01172"
                     /aSTool="tigrfam"
                     /description="cysE: serine O-acetyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg1_1897_0037"
                     /evalue="1.20E-68"
                     /identifier="TIGR01172"
                     /label="ctg1_1897"
                     /locus_tag="ctg1_1897"
                     /protein_end="243"
                     /protein_start="83"
                     /score="228.2"
                     /tool="antismash"
                     /translation="YDLLATQQRDPAAVHYFEIMLFLKGYQALQAYRLSHWLWKNGRRT
                     MAYFIQNRMSEVFAVDIHPAAVIGKGILLDHATSLVIGETAVVDDNVSLLHEVTLGGTG
                     KESGDRHPKVHKSVLIGAGAKILGNVIIGEGSKVGAGSVVLDDVPPHYTVAGVPAQ"
     PFAM_domain     complement(9060..9374)
                     /aSDomain="SATase_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06426.16"
                     /description="Serine acetyltransferase, N-terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg1_1897_0157"
                     /evalue="8.00E-27"
                     /label="ctg1_1897"
                     /locus_tag="ctg1_1897"
                     /protein_end="114"
                     /protein_start="9"
                     /score="93.7"
                     /tool="antismash"
                     /translation="IWSTIVAEAAAECLRDPEISIFLEQHIIRYDNFGASLAMLLSVKL
                     GSKHFPPLVLQGLFEDFYRHCPEQVENAIYDLLATQQRDPAAVHYFEIMLFLKGYQALQ
                     A"
ORIGIN
        1 ccgataaagg atcgagcaaa tactcttttt ccgtaaaaac aaccgtcgca tcatcaagag
       61 agctgagaga agaaacttcg attcgtgtgc cgtcaagaaa tgctccgcac cctgtttcag
      121 cataaaaaag ctgcccaaga gcaggaaatc cgacagcacc aagccgcggc aaaccttcct
      181 cttcaagtgc aatcaatact ccataaagag gaaccccgtg aataaaagat ttcgtaccgt
      241 caataggatc aataatccac cggcgcccgt tatctgcatg cttttcatca aactcttccc
      301 caagcagacc atctcgtgga taccgtgcgc tgatcccttc tctgatgagt atttcagcat
      361 tccggtctgc ttctgtaacc ggagtagcat cacgtttgga aaaaacctgc aaggatttcc
      421 tgttgaaata ttcgagcgtt aaccttccgg cacgatcggc cagttcaagg gcaagctgaa
      481 gctcaggact catcggcaat gttatattta aaatggtgac aaaaaaaaca aattattcag
      541 gctgagaaca tttgatatgg catttcgccc cctcggtgac tgtatcatgg cgacagcttc
      601 tgacgttccg gattcaccac cgccactccc atagggatcc ctctctgcgt tcgggatgac
      661 aagagagcgc gtcagggatc gcaagcggaa actcgggata aaaaaccaaa cattctaact
      721 cgtaaatttc acacgtagca cctgatacgt atctcctccc gccgtacgcc tacctcccca
      781 ttccctcgcc aagaggatga tgacgttcaa atgagcgaac tgccttctgc atattccagc
      841 ccgaagaggt aatatttttc agatgtgcaa ccatcatgtt cagaccctct gcaacaggaa
      901 gaagatccga atcggaaatg gtacaaaaaa ccgatgcgag atgctcgcgc ccggcatgaa
      961 ccgagatctc gtaacgcccc ttctcaataa ggctggcata aaaatcctga acattcagat
     1021 caagaatatc agagagcacc tcaagaaaaa gcggctcctg caacccgtta taaaaaccaa
     1081 cctgcaagcg aacaagagga tagtgctgtt cagcaaaaaa tgagatccga aacctgaatg
     1141 tccgattcat gatactctcc gttatcgccc ctgcttcatc ttccacgccg gcatatccga
     1201 gatcgagaag tactcttgcc atgcctgata acgatgtcaa tgcgggcata ttgagttcaa
     1261 gtgaaccggg ataaccaaac accgtgggag actcaccagt tatcgatatc gtaccggaaa
     1321 cccgggaaag tctcatactt gaagcctgat ccggaggcag gcttctgatc atttccgaat
     1381 accctggatc agcttctcta aaacgcttgc ctgtgctcca cgtcgaaatc ccctcaaaca
     1441 gtgacgtcat atcaggcttc cgcaattccc gggaaacgat ggctggtgca ttcgactcct
     1501 tcttaaagaa acggtcaaaa atacccatgc cgaacctcct tcagagttta aaaaaaattg
     1561 aaacacaaca aaaaacagtg gtttatttct gtgttttttc agtcaataac agcaaacggg
     1621 agaccttctg caaaagattt ttactgtcga caggttttat aagataatca ttcataccgc
     1681 tctccatagc acgacgaacg gtttccttgt caccatcacc actcagacag ataatcggaa
     1741 tgccgcggta accactcttt gttgcacgaa tgcgctttgc cgcttcaagc ccgtcaagaa
     1801 caggcatttg aatatcgata agcaaaagat cgcatggata atgttcaagg atatcaatgg
     1861 cctcctgacc gtttttcgca tcaagaaccg ttaaaccgcc ccgttgcagt atgtttttga
     1921 cgaccatacg attaagggca gaatcatctg cgacaagcac cgtttttccg gccagagagt
     1981 ttttcagggt atccggtttt gtctcgatcg cttccgcaag caccgaaaga agctccgcca
     2041 gaactatggg catggaaagc agtgcctgta tacctaactt ttccgcacgt cccttcaaca
     2101 acgtcgagga cattcgggta taggcgacga tcgacagaac gacgccgttt tcctgcattc
     2161 tgaaagcaag ctcatagccg tcaataatcg gcagttcaag atccagaaga acaaggtcat
     2221 attgtcttga tgctatcatc tccattgcct ctgctccgct ctgaacctga tcgagctcaa
     2281 cactgagcgg caaaagatac cgggcaatca atacaagatt tgccggatca gcaccaacat
     2341 gaagaatccg ctttgccgaa aagagttcat gatattgagc ataaagatct gcctcaaaat
     2401 cggcaatatc gccatcactc accggaggaa atgtcagtat aaattcagtg aattcatacc
     2461 gaacagaacg acagacaata tctcccccga aaaaacgcat aacccgcttg cagtaggcaa
     2521 gaccaagacc agtcccgcct tttctgccgg aagtataaaa agggtcaaac aactttgcaa
     2581 gattctcttt agcaacgcca gggccagtat ctcttactgt aacactgttt aagatctccc
     2641 ctcttttgag acggatatcg atgcgaccgt cgggaaaaga gcggagaaaa tagagcgcat
     2701 tcatgacaag attgaaaagc acaaaaacat acatggtctc tacacccttg aaaacaaaat
     2761 catcgtcttc aaaaaaatga acgcgttgac gctcttcttg cgattcgtag ccatattcat
     2821 caatagcctt gcgagttatt gccgcagcgg acagataggt taatccggca tcctctgaag
     2881 catcttccct gacctcttca agaatcatct caatgacctg aatgcccctg ttgactgcta
     2941 tctgacctcg ggcaactttt tcatagattc gttcgactcc tcctgcgctg atcgaaggat
     3001 agagcctttc tgcatgatag agcgggagtt cttcctgaat ggattcaaga ttatagcgta
     3061 tctgacccag aggattacgc atctcatggg caatgccggc cgcaagagcc ttaagggcat
     3121 tgtttctctc catggccata atcccccttt tattgctgta gctgaagaca taaccggcaa
     3181 caatggtaaa caccagcacc agaagataga gtggaatatt gaattcggga tggagttcga
     3241 cgcgtggagt tgaaagaaaa taaaatacaa ccgccccggc aaaacccaga agcagatcaa
     3301 aaagaaacat cagccagttg ggaacaaagg caataagcac aaacagcata aaaatttccc
     3361 agtacagcca cagctcatga aagttgttca tgataagatt gaccgtaaaa acaaagggaa
     3421 gaacaaaaat tatggtgaaa tgccagaaaa aagtgaaccg ggtctgaata aaaccgggaa
     3481 gtctgctctt gaaaagcacg gcaagacaca agagcgttgc cgtcagacga aggaacaggt
     3541 tttcataagg aagatcaaaa ccatatttga aaataaaata aaaaaagaaa tgggctggag
     3601 cgccaagaag cccggctgca agcgtattga aacgtgatac ctgagtaccg tcaattacac
     3661 actgtcgaat gtaggccaac accttcaatc cttacccccg tcaagtaatt tatgcacaca
     3721 ctcccccgct gccctgaagc acgcctctat ggatgcgcca cgacgataat cacccgttgc
     3781 ggcaaaaccg gaaaaaaagt caagcttctg atcaacctca gcaagaagtc gatgatggta
     3841 tggcgaatag gcacaaagtc cctcggaaag ataccgaaaa acaaaagact ctctcgtatt
     3901 atcctttatc gtgaaatagc gtccggcgat ctcctctccg agtgtaataa ccgcttcagg
     3961 ctgagaccga tcggacacca tagctcttgc tgccctgccg ctgaaggtat accgaaccag
     4021 atcaagatca ttgataccat aagctccggc attactcaac ggaaacgagt catcaaaaac
     4081 catggcgcgc tgctctttcg gaaatacatt ctgacgatat ttcacaatag caactgctac
     4141 aggaaaatac tgtatccgcc ttaaaagaac tgaaacttcc ggacaaaacg tttcaagaag
     4201 ttcactcaac cgaagcgcag gcagagcgga cactacccga tcatactccg ctgataaaga
     4261 acggccctca tactcataac cgatcatgac tgctcctttg ccatgatcac ggttaacaga
     4321 cgtaacccga tgtgccggaa gaattctcaa caaagcagat cttgccggga gctgaaaagc
     4381 ttcaagcatg ccatgcatac cctgttgcaa ctgctcgtaa ctgtcaagca gaagtgcgag
     4441 attagagccg aaattccccg gataacactc atcaggttca gccccattca tccttaccgt
     4501 caccggcctt acgatatgac ttaaacaggg ctccttcagg tatccagcaa gggagagatg
     4561 gtcatactct tcagcaagtg cagaaaaata ctcgctggca agaacccctt gacgacgatc
     4621 attgagaatt gccctgacat ggggatagag ctttcgaagg ccgctaaaac cgcataaacc
     4681 gaaaaaacga atggcattga aaagtctggc cccctctttg ttaatgctga caacccggcc
     4741 tccaatgacc tgtgatgtat taaaaccaaa atattcaaaa tcagaaacac cgcaatccag
     4801 aacaaaatcc cgaaacaagc ggtaattttt tccgatattt ttgccgccga aatcaagcca
     4861 cctctcacca agccgttcac tgccaatcct gcccccaata cgatcagccg attcgtaaag
     4921 atcaacactg atattgtgct gcatgagata atatgcggaa gcaattccgg aaattcctcc
     4981 gccgataacc gctgccctca tcatactgaa gctgcctcgt gcagaatccg gttgattttt
     5041 gcgtcaaatt gcattttact tcttgtacat attttttcga ccctttttct ctgttcctca
     5101 taccgttttg aactcataaa cgcaaaagct ttcagcgttg catcagcaac aaccctcccg
     5161 tactgcagaa cctgaatgta gattggcgca tccttatcct cgcttgtctc gtcggcagta
     5221 aaactgcaat ataccctcag cacaacagga acatcgtttt caagataatg aaaaaaattc
     5281 gtattatagt tcaataatgc aagtcctccg tcaaatgaga gtccctgaat atgagcggtt
     5341 gcaacgccag cctgtctcaa agcctcgagc atcagcaatc cctgaacatg atcggaaacg
     5401 tgatcgaatg agatctcttc cgtgctggca agcatattga aatacagcat gcgaccggct
     5461 gaaaaataat ccgaaatcaa cacattggaa ctatttttct tatgcacata ttttttttct
     5521 atcgaacatg gcagcttgtc atctccggtt attgcgagag gacttttcaa aagagatttc
     5581 agatcaaaag gaagtttttt cattaaatcc gctgccgtct caatatcaaa aggtggctta
     5641 tccttgcgtg aagggcaata aagtgctttc gccgcagcat aaacgccggg attggctctc
     5701 cggtaatcaa gcgagatgaa cagttcacag gtatccccca gaagcagaag aaaccgggaa
     5761 gcctcttcaa ctgaagagac attgacaatc tgcagagcgg taactgattg cagaggaagg
     5821 gtatccccct ccagcagcat cgtaaaaggt tttttccctg gactgagggt tagaatacca
     5881 aaatctctgc ctggcctttt gatggttctc tgaaaccgaa gacgaggcgt tgggttcggg
     5941 tgaaatgcag gatgaaaatc gtgcccggcg attctttgta cagtttgctg tagcatggta
     6001 tcaataaatt acattaagta ataatggccc gaattatgta gcaatataac cttgtttgtt
     6061 tcagggtaac gggctttaaa aatgaatgtt aacaggttcg caacaatccg gggaatccga
     6121 gaagctctac aggaaaaaaa gtcatccggc ttataattaa ccatataact cacctgcgtc
     6181 ctgaaccacg ctcagaatat ctactcacca gacaacgggt cacggcagac ctgagcttca
     6241 atgtaccctt gtattttcgg ttatgcttcc ggaagtttcg ggattttctt atttttggct
     6301 ttttaaacca ttaatctgcc atcatccatg agccagctcg acttactcaa tattgtccat
     6361 cgtcccagaa gactccgcaa aacagccgca atcagaaacc ttgtacagga acacaccctg
     6421 tcagtcaacg accttgtttt cccgctcttt gtctgccctg gaaccagcgt tgtcgaagag
     6481 gtttcctcca tgcccggcag tttccgctat tccattgaca acgcggtaaa agagtgccag
     6541 gaactatggg atctcggtat acagagcatc gatcttttcg gtattcccga gcagaaaacc
     6601 gaggatggaa gcgaagccta caacgacaag ggaattatcc aggaagcaat ccgcgccata
     6661 aaagccaagc tccccgatct ctgcatcatg actgacgtcg cgctcgaccc ctttaccccc
     6721 ttcggccatg acggtctggt aaaagacgga ataatcctga acgatgaaac cgtcgaggta
     6781 ctctgcaaaa tggcggtttc tcatgccaat gccggcgccg atttcgtatc gccgagcgac
     6841 atgatggatg gtcgtatcgg agcaatccgc gaatcacttg atgatgcagg ctcctccgat
     6901 gtaggcatcc tctcctatgc cgccaaatat gcttcaagct tttacggccc tttccgcgac
     6961 gcactccatt ccgcaccaca gttcggcgac aaatcaacct atcagatgaa tcccggaaac
     7021 tccgacgaag cgatgaaaga gatcgagctc gacatcatgg aaggcgcaga tatcgtcatg
     7081 gttaaacccg gtcttgccta tctcgatatc gtatcacgca ccaaagaacg tttcgacgtt
     7141 cctgttgcca tttaccacgt atcgggcgaa tattccatgg tcaaagcggc agcagcacga
     7201 ggatggattg atgaagagcg ggttatgatg gaatccctgc tctgtatgaa acgtgccggc
     7261 ggtgatctta tctttaccta ttatgccaag gaagctgcaa aaaaacttcg ctgatccctg
     7321 ataaacagca gaagatgact caacaagccc ggctgcataa attacagccg ggcattttac
     7381 tcttaatacc tatgatacga tatctgacct caggggaatc gcacggcccg gcgctttcgg
     7441 caattgtgga gggagtcccg gccggcgtcg gcattacccc cgaaatgatc aacaccgagc
     7501 tcgcccgacg ccagcaggga tacggacgcg gcggacgcat gaaaatcgaa accgaccagg
     7561 cggaagtcct gtcaggtatc cgcttcggca aaaccatagg ctcaccgatc actctgatca
     7621 tcagaaacag ggattgggaa aactggacga caaccatgtc gcaattttca gaaccggcag
     7681 aagatattgc aaaaataacc atcccccgac cgggccacgc ggatctgaca ggaaaaatca
     7741 aatacggcct gaacgatatt cgcccggtta ttgaacgctc ttcggctcgg gaaaccacgg
     7801 caagggttgc agccggaaca atttcccgaa ttttcctcaa agccatcggc attgaaatcg
     7861 gcagctatat atcggcaatt ggttcggcag gcgaaacaac tgccgacact cagattgaaa
     7921 aactgctccg gagcggagcc gaaacccttg cacggaaggc agaccggtca gcggtgcgta
     7981 tgctcgacaa aaaaaaggaa gccgaagcaa ttatcgctat tgatgcagcc aaggatgctg
     8041 gagatacact cggcggcatc atcgaaattt tcatcaccgg cgtaccaatg ggactcggca
     8101 gctatatgca gcacgaccgc cgtcttgatg ccaatcttgc tgcagcactc atctcgattc
     8161 aggcaatcaa gggagttgaa atcggtacgg cgtttgcaaa cgcactcaaa ccgggatcac
     8221 aggttcatga cgaattcatc atcgaaccgg agaaagggtt aacgcgaagc tcgaaccggg
     8281 caggaggaat tgaagggagc atgtcaagcg gccagaccat tcatctcaga gcagcgatga
     8341 aaccgatatc ctcgcttctc accccactgc actcgtttga cagcgaaacc ctgcaaccga
     8401 cactctctcg cttcgaacga agcgacacct gcgcagtgcc tgctgcgggc gtcgtagccg
     8461 aagcgatggt atcgaccgtt atcgcaaacg ccgttctcga aaaattcgga ggcgatcatc
     8521 ttggtgaaat acagacaaga atctcccttc accgtgacct cacccgaaaa gcgttcatcg
     8581 cctgaagaga ctcaggagcc ttctgacgga gaaccgacaa gtctctggtt catgtcacgg
     8641 gaaggctccg gcacctcggt cttgccgaca atttgagcgg gaacaccggc cacagtataa
     8701 tgcggcggca catcatccag caccacgctg ccagcgccga ctttcgatcc ctcgcctatg
     8761 atgacattac cgagaatttt tgccccggca ccaatcagca ctgatttatg caccttcgga
     8821 tgcctgtcgc ctgactcttt tccggtaccg ccgagcgtca cctcatgcaa cagcgaaaca
     8881 ttgtcatcaa caaccgcggt ttcgccaatc acaagactgg tggcatgatc gagaagaatc
     8941 cccttgccaa tcactgcggc aggatgaata tcaacggcaa acacttcgga catgcggttc
     9001 tggataaaat aagccatggt tctgcgcccg ttcttccaga gccaatgaga aagacgataa
     9061 gcctgtaatg cctgatagcc tttaagaaac agcatgatct caaaataatg gaccgcagca
     9121 gggtcacgct gctgtgttgc aagaagatca tatatcgcat tctccacctg ctccggacag
     9181 tgccggtaaa aatcctcaaa aagaccctga agtaccaggg gaggaaaatg ctttgatccg
     9241 agcttcaccg aaagcagcat tgccagcgac gcgccaaaat tatcgtaacg aataatatgc
     9301 tgttcaagaa aaatactgat ctcgggatct cgcagacact cagccgcagc ctcggcaaca
     9361 atcgttgacc agatactctc aataggtata tctctcatca ttggaaacat caacaccatt
     9421 taaacgatag aaaaatcaat tgatgaactg caaaaaaata tgaagcatca acacgatgcc
     9481 tgacacatcc ataagcatta atagctgttg ctgcataaaa ggttctcctg accgctggta
     9541 acagcttctg aatttaaaaa aaaacaagcc ccattctcca catatttcac cgcctggcac
     9601 tgaattgccc tgccagactc tgtcaaggcg tcaacatcgg gatccatcca ctctgtcggg
     9661 atgacagacc ggccgactca tcatgtcagg gaaaaaatcc agccatgata aacttaccag
     9721 cagaatcaca agaaaccatg atcgacagct cttgagtaat gcggggccag gataaaaaac
     9781 agaacagcag gtaaaccatt ttacagagta atccggatat ttattaatct ttactgacaa
     9841 atagtatatt tgagtgctaa aatccggcat tgtgctatct cctgcaatga gtgccctgat
     9901 ctcgatgctc acaggattct gatacaccct tctgtttccg gtgcattatt aaacaaggtt
     9961 tagtccgttt caggttatgg tggttacccg acgtcgctgg tttgaggctc catgggagtt
    10021 cagggaagca tccctgttca gcctgcttgc tatcctttca ggctttttca tacaatatgc
    10081 cgcatccggc aacagcgtcg gacttcctgt ttggccattc aatgccatag cgctttctgt
    10141 ttttgccgca ctgattttcg gtatcgggct tatcctgaga aacaatcctc ttgtcgcctg
    10201 gttcggcggc attccaatgg gcctcagcct tattcttgca cttgcggcac tctcctttat
    10261 cggcgggatg gtgcctcagg aaatcatgac cggggactct ctctataccc gcttgcgaat
    10321 caaccagatt ttttcaagct ggccgtttgc cctgattgtt tttctgtttc tgatcaacct
    10381 cggtttttct cttgcatgga aactcattcc cttcagatcg aaacatctgc agttcgttct
    10441 ttttcatgcc ggcttctggc tggcactttc atgcggcatt cttggaagct ccgaccttca
    10501 gcgacttgtt attccgattg aagagggccg agccaataac cttggctact cgatgcaaag
    10561 caaagaccct gtgccgttac cgttttccgt ttttcttcac gatttttctc tggaggagta
    10621 ttcgccccag atacttctct atgatcctga aaacgacaaa cttctcatgg ataaatctca
    10681 agccattatc gaagtccata agggaacgaa agccgcatgg aaagggcttg aggttgttgt
    10741 cctcgatttt ctccctgcag ctcttccggg aaaagacggg attcctcgcc tttccgggct
    10801 tccggcagca attccctatg ccagggtcag ggtactctct gccggggctc aggatgagat
    10861 gtggatcagc acaggaagcc ctttcatgag acctgaagcg gcaaaaatcg gaaacttctt
    10921 tctgatcatg gttccgggta cgccaaaaac gttccgttca gtcgtaacaa ttaaggacaa
    10981 atccggtcac ctgatc
//
