LOCUS       c00004_NZ_JARF..       10287 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_JARFMK010000013.1 Bradyrhizobium yuanmingense strain ALSPC2061
            NODE_13_length_233243_cov_41.4641, whole genome shotgun sequence.
ACCESSION   c00004_NZ_JARF..
VERSION     c00004_NZ_JARF..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 14:27:07
            Original ID  :: NZ_JARFMK010000013.1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10287
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10287
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[4900:5287](-)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(4901..5287)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     cand_cluster    1..10287
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10287
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ectoine"
                     /region_number="1"
                     /rules="ectoine_synt"
                     /tool="antismash"
     aSDomain        complement(2..1126)
                     /aSDomain="TIGR01733"
                     /aSTool="tigrfam"
                     /description="AA-adenyl-dom: amino acid adenylation domain"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_1_0001"
                     /evalue="1.30E-107"
                     /identifier="TIGR01733"
                     /label="ctg4_1"
                     /locus_tag="ctg4_1"
                     /protein_end="1007"
                     /protein_start="632"
                     /score="358.1"
                     /tool="antismash"
                     /translation="SYGELNARANRLAHHLIGFGVKPDQPVAICLKRGLAMVVGVLAIL
                     KAGGAYLPLDPAYPSARLRQIVDDAAPRLLLCDAAGRTALGAEAVADVSVVDLDTAAPV
                     WAERPDSDPDPRTLGLTSRHLAYVIYTSGSTGTPKGVEMSHGSLVNSLAGIGTSKRCTL
                     QFATLNFDVSCQEMFICWKDGGLLVLLREETRSHFPELLECIKKEAIERLFLPFVALNH
                     FAEVWGAQQVKLPSLSEVYTAGEQLQATPLLRAFFEVHPKARLINQYGSTEISVIAEHH
                     LAADPSCWPQSPPVGRPIANTRVYLLDGCGTPVPFGAVGELYIGGAGVARGYLNRPELT
                     AERFIASPFVDGDRLYRTGDLGRYLPDGNLEFLGR"
     aSDomain        complement(2..1189)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_1_AMP-binding.1"
                     /evalue="2.60E-101"
                     /label="ctg4_1_AMP-binding.1"
                     /locus_tag="ctg4_1"
                     /protein_end="1007"
                     /protein_start="611"
                     /score="331.0"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="FEAQAHKAPKALAAVYENERLSYGELNARANRLAHHLIGFGVKPD
                     QPVAICLKRGLAMVVGVLAILKAGGAYLPLDPAYPSARLRQIVDDAAPRLLLCDAAGRT
                     ALGAEAVADVSVVDLDTAAPVWAERPDSDPDPRTLGLTSRHLAYVIYTSGSTGTPKGVE
                     MSHGSLVNSLAGIGTSKRCTLQFATLNFDVSCQEMFICWKDGGLLVLLREETRSHFPEL
                     LECIKKEAIERLFLPFVALNHFAEVWGAQQVKLPSLSEVYTAGEQLQATPLLRAFFEVH
                     PKARLINQYGSTEISVIAEHHLAADPSCWPQSPPVGRPIANTRVYLLDGCGTPVPFGAV
                     GELYIGGAGVARGYLNRPELTAERFIASPFVDGDRLYRTGDLGRYLPDGNLEFLGR"
     PFAM_domain     complement(2..1189)
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_1_0002"
                     /evalue="1.20E-89"
                     /label="ctg4_1"
                     /locus_tag="ctg4_1"
                     /protein_end="1007"
                     /protein_start="611"
                     /score="301.0"
                     /tool="antismash"
                     /translation="FEAQAHKAPKALAAVYENERLSYGELNARANRLAHHLIGFGVKPD
                     QPVAICLKRGLAMVVGVLAILKAGGAYLPLDPAYPSARLRQIVDDAAPRLLLCDAAGRT
                     ALGAEAVADVSVVDLDTAAPVWAERPDSDPDPRTLGLTSRHLAYVIYTSGSTGTPKGVE
                     MSHGSLVNSLAGIGTSKRCTLQFATLNFDVSCQEMFICWKDGGLLVLLREETRSHFPEL
                     LECIKKEAIERLFLPFVALNHFAEVWGAQQVKLPSLSEVYTAGEQLQATPLLRAFFEVH
                     PKARLINQYGSTEISVIAEHHLAADPSCWPQSPPVGRPIANTRVYLLDGCGTPVPFGAV
                     GELYIGGAGVARGYLNRPELTAERFIASPFVDGDRLYRTGDLGRYLPDGNLEFLGR"
     CDS             complement(2..3022)
                     /NRPS_PKS="Domain: AMP-binding (611-1007). E-value:
                     2.6e-101. Score: 331.0. Matches aSDomain:
                     nrpspksdomains_ctg4_1_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228:methionyl-tRNA formyltransferase (Score: 123.2;
                     E-value: 1.7e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_1"
                     /sec_met_domain="AMP-binding (E-value: 1.6e-93, bitscore:
                     307.4, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYRVSPARGSVCQPGDQDRLPARSISSAVVVGSGTLAIRCVQLA
                     IEMGHVIGAALCADGVFRDWAVRSNIPSIASVEELSSFLKAAPVDFIFSVANPFILPAD
                     VLEWVRRGAFNYHNGPLPRYAGTHVTSWALLARETEYAITWHLIDDGIDTGDIVVQRQV
                     LIAPTDTALTLNLKCHEAAVEGFRELLTGLHNGELLAHPQALVDRSYFPRHRRPDSAGC
                     LRWDQSAQEISAMTRALGFGPHDLNPMCLPKVLIGDQAVEVRNLKVLARSAGRPAGSLI
                     EVHASHWRVATGTEDVEVYFEEPDGQKLDARALARHFNVDEGSRLPILSDEQARSITAA
                     HEMLAPLEDFWRQRLGQFRRLRPPFLSSSVAAAPPEWQSSSWFTPSALAKLSPRDRSEY
                     LATAWLIYLARITGERELQLGWTPASDGSQAASKVMEVLISSVVPMEVTIERANDFEEV
                     RKTVAAELAQLRAHGSFARDLIARCPELRGVEALHSHRPWPIGITITTQSCSVAGDLMT
                     SHKAGPALCGDLLTFEVCALDGSFRWHFDASRFAPRQIGRMTQHLETLLDGVMADAGQP
                     VGRTDILPADERKYLLEELNRTATPYRSERYIHELFEAQAHKAPKALAAVYENERLSYG
                     ELNARANRLAHHLIGFGVKPDQPVAICLKRGLAMVVGVLAILKAGGAYLPLDPAYPSAR
                     LRQIVDDAAPRLLLCDAAGRTALGAEAVADVSVVDLDTAAPVWAERPDSDPDPRTLGLT
                     SRHLAYVIYTSGSTGTPKGVEMSHGSLVNSLAGIGTSKRCTLQFATLNFDVSCQEMFIC
                     WKDGGLLVLLREETRSHFPELLECIKKEAIERLFLPFVALNHFAEVWGAQQVKLPSLSE
                     VYTAGEQLQATPLLRAFFEVHPKARLINQYGSTEISVIAEHHLAADPSCWPQSPPVGRP
                     IANTRVYLLDGCGTPVPFGAVGELYIGGAGVARGYLNRPELTAERFIASPFVDGDRLYR
                     TGDLGRYLPDGNLEFLGR"
     CDS_motif       complement(95..184)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0005"
                     /evalue="1.80E-19"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg4_1"
                     /protein_end="976"
                     /protein_start="946"
                     /score="61.7"
                     /tool="antismash"
                     /translation="PFGAVGELYIGGAGVARGYLNRPELTAERF"
     CDS_motif       complement(692..751)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0004"
                     /evalue="3.50E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_1"
                     /protein_end="777"
                     /protein_start="757"
                     /score="31.7"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGTPKGVEMSH"
     CDS_motif       complement(962..1003)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0003"
                     /evalue="5.80E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg4_1"
                     /protein_end="687"
                     /protein_start="673"
                     /score="19.3"
                     /tool="antismash"
                     /translation="LAILKAGGAYLPLD"
     CDS_motif       complement(1013..1039)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0002"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg4_1"
                     /protein_end="670"
                     /protein_start="661"
                     /score="-2.8"
                     /tool="antismash"
                     /translation="CLKRGLAMV"
     CDS_motif       complement(2177..2209)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_1_0001"
                     /evalue="7.70E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_1"
                     /protein_end="282"
                     /protein_start="271"
                     /score="-2.6"
                     /tool="antismash"
                     /translation="SAGRPAGSLIE"
     PFAM_domain     complement(2462..2797)
                     /aSDomain="Formyl_trans_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00551.21"
                     /description="Formyl transferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_1_0001"
                     /evalue="5.00E-19"
                     /label="ctg4_1"
                     /locus_tag="ctg4_1"
                     /protein_end="187"
                     /protein_start="75"
                     /score="68.8"
                     /tool="antismash"
                     /translation="SVEELSSFLKAAPVDFIFSVANPFILPADVLEWVRRGAFNYHNGP
                     LPRYAGTHVTSWALLARETEYAITWHLIDDGIDTGDIVVQRQVLIAPTDTALTLNLKCH
                     EAAVEGFR"
     CDS             3337..3552
                     /locus_tag="ctg4_2"
                     /transl_table=11
                     /translation="MYCAKGGIVPSQYAGPNTAMSLIRPRRTSYQLSALSIGPRLLESR
                     LMCFGQRKEEPRTSKRFFRGAPAFQV"
     CDS             3978..4484
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 71.2; E-value: 1.4e-21)"
                     /gene_kind="other"
                     /locus_tag="ctg4_3"
                     /transl_table=11
                     /translation="MAGLDRRVQAMIAFIDDHHGAQVGEPIQGLAEPPFGLPCRSSQAV
                     SARPAARGDEDRRSARLQSDFSVYGVRKVPRSGASSSAEIFHIVRSTVSPLMRDMGLQE
                     TIRGKPVKTSSDKAAACQQDYVDRQFQSSRPWHSDFTYLATWTGSVYVAFVIGAYARSI
                     VGWRA"
     CDS             complement(4901..5287)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_4"
                     /sec_met_domain="ectoine_synt (E-value: 2.8e-32, bitscore:
                     105.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRSLHDIEATDHFVDWGNGTSHRLLTAKDGMGFSICHTVVRAN
                     TISLLQYRNHLEACYCIAGEGEVEDMDGNVFPIRKGDMYVLDKHDKHLLRGGRDKDLIL
                     VSIFNPPLNGTERHKLNDPAGSAY"
     PFAM_domain     complement(4928..5287)
                     /aSDomain="Ectoine_synth"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF06339.14"
                     /description="Ectoine synthase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_4_0003"
                     /evalue="2.70E-39"
                     /label="ctg4_4"
                     /locus_tag="ctg4_4"
                     /protein_end="120"
                     /protein_start="0"
                     /score="134.4"
                     /tool="antismash"
                     /translation="MIVRSLHDIEATDHFVDWGNGTSHRLLTAKDGMGFSICHTVVRAN
                     TISLLQYRNHLEACYCIAGEGEVEDMDGNVFPIRKGDMYVLDKHDKHLLRGGRDKDLIL
                     VSIFNPPLNGTERHKL"
     CDS             complement(5350..5577)
                     /locus_tag="ctg4_5"
                     /transl_table=11
                     /translation="MKLAQSILMPPRPPRRHGGEVSRLMIGLRLRGEVRRRRIRNGRVA
                     AEDMDWQALDGLPRPNSPRLSASGAQKPRF"
     CDS             complement(5929..7341)
                     /locus_tag="ctg4_6"
                     /transl_table=11
                     /translation="MTDEINRPKDVQINAWNGESTAGDVLPSRTPWAQSQRLVPALSAA
                     QLAAPQEIDERNWSDPRIGWGVVLLDNDVLSNSDRSTAVDAPPAIRRLIEKRSNAPVLR
                     WRSSLGQGFLRRYYPDGNFHDLSTLAPKVGTGKGCIPQYLLLYGSPTQLPWALQYALQM
                     SLFVGRLDLVDTALDHYVDALIDDWQGQFSDPKAPVVWSVDLGKNDITWLMARAVAGKL
                     WEKIDGNNDLVRRRRIADTSANRSSLVASLTELSPALLITTSHGMTGPLDDDVRLKSWI
                     GAPVDIDHKVVDGTQLQMWQPSGAIWYSHACCSAGSDSVSRYKGLLPESGTISTVLNRI
                     ATVAGAAIAPVPRALLGAEKPLRAFVGHVEPTFDWTLRDPANKQVLTHVLCSALYDRLY
                     LRYERNPLGWALQKVYREAGAFYAAWQDAIAGINAGEPSMRDFALYRQLVAMDRQTLVI
                     IGDPTVSLPGIA"
     CDS             complement(7338..8702)
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MRDTIVSIIGGGNNDMIVCLESQSNHPYALEFRSLDLDAEAMPPL
                     DTETNVTAYGAAVHKALSDHPAIKAELTHMFGQQVPQRAALRFLMKAPDAERFRWEAIH
                     GGAEPRFLAMSELCTVSRLAPARIGSTLKAFTRPLRMFAFLSAAGIKADREMKTICDQI
                     VESKQNGLEIECTVFLAEQALLDEYRHKTAVGPLHNTGITIEQMPSTATQVANLLRDAP
                     VQFVHFFCHGIDRLGIQGLSIATTSDHEANEANGNADSSSIFLSVTALSEALALNSSVW
                     VTVFNSCSGAEVLHQLFSMALTVARKGCPYTVGMAEPIDTAAATTFTQAFYRELFRIVG
                     SKLTPEPAAGPVIFDFAPAVIPARRIIHDHCCAVPGGFGRWLLPVLYEASHKPFLALQL
                     PADVASRVLAVARTLRRMEEETPEEVRDQIAALLDNPPSVPPHFRPNRFGEFATP"
     PFAM_domain     complement(7692..8531)
                     /aSDomain="CHAT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12770.9"
                     /description="CHAT domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_7_0004"
                     /evalue="1.10E-07"
                     /label="ctg4_7"
                     /locus_tag="ctg4_7"
                     /protein_end="337"
                     /protein_start="57"
                     /score="31.7"
                     /tool="antismash"
                     /translation="VHKALSDHPAIKAELTHMFGQQVPQRAALRFLMKAPDAERFRWEA
                     IHGGAEPRFLAMSELCTVSRLAPARIGSTLKAFTRPLRMFAFLSAAGIKADREMKTICD
                     QIVESKQNGLEIECTVFLAEQALLDEYRHKTAVGPLHNTGITIEQMPSTATQVANLLRD
                     APVQFVHFFCHGIDRLGIQGLSIATTSDHEANEANGNADSSSIFLSVTALSEALALNSS
                     VWVTVFNSCSGAEVLHQLFSMALTVARKGCPYTVGMAEPIDTAAATTFTQAFYRELFR"
     CDS             complement(8706..10145)
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MSGQSSSPPLIILQVTLTFWEASPQIELLLIRGVGTAGSTESWQI
                     PARELGVPSSIETDAAPDLNLWPQITSGIKNSLKGDAKDLPLWLRFAKPHGYVSVLPWE
                     RALTETLERPVLRFPDLLERPCEDRDVLELAIWFDPDRSAPLTNVQTLLNQIVETILSA
                     SPRAQSRVHLFTASFWHRLLEKDGYDKRLRIHDPMFAPTSAAVFSKGPIEPPFQSLWWV
                     WMKAALGTRSLDAIFFVCNSGMTEFGPALRMSNSIAPNEKYESYSYVDAMDLAAIVTRA
                     GAWAALFSNSPSGAARPMLALAADALAHTRPTAVLYQPLGSSQQIASLRAACSFLFAAN
                     SAPAPSMVDGFLYCPPNYVDAYESLHISSPLPALKANASIFHSASIADRTPPHMSSDTQ
                     GIPDYEMKQAPSWATSLQRQCEFSALERLRRNASDVLLSSSDNARTQVTPDESVESIAG
                     SDDTLEQIHKVVGNYLRKLGG"
ORIGIN
        1 tgcggcccag gaactccaga ttgccgtccg gcagataacg cccgaggtcg ccggtcctgt
       61 acagccgatc gccgtccaca aagggactgg cgatgaaccg ctcggctgtc agctcggggc
      121 ggttcaggta gccccgcgcc actcccgccc cgccaatgta aagctcgccc accgccccga
      181 acggcacggg cgtgccacaa ccgtccagca ggtacacccg cgtgttcgca atcggacggc
      241 caacgggagg cgactggggc caacatgatg ggtcagctgc aaggtggtgc tcggcaatga
      301 cgctgatttc cgtggacccg tattgattga tcaatctcgc ctttgggtgt acttcgaaga
      361 aggccctaag cagtggagtg gcctgcagtt gctcacccgc tgtataaacc tcacttaagg
      421 agggcagctt cacttgctgc gcgccccaga cctccgcaaa atggttcaat gctacgaatg
      481 ggaggaacag tcgctcgatc gcctcctttt tgatgcattc gagcaactcg gggaaatggc
      541 tacgggtctc ttcccgcaga agtacgagca gtccaccgtc tttccaacaa atgaacattt
      601 cctgacagga cacatcgaag ttgagggtag cgaattgaag tgtgcatcgt tttgacgtgc
      661 caatccccgc gagcgaattc acaagcgagc cgtgggacat ttctacgccc tttggcgttc
      721 cagtggagcc tgaggtgtag atcacgtagg cgagatgacg ggatgtgagg ccaagcgtgc
      781 gcggatcggg gtccgaatcc ggccgctcgg cccagaccgg ggcggcagta tccagatcga
      841 ctacgctgac gtcagccaca gcctcggcgc ccaacgcggt tcgaccggcg gcgtcgcaaa
      901 gcagcagtcg cggcgcggca tcatcgacaa tctgccgcag ccgcgccgac ggataagccg
      961 gatcgagcgg caaataggcc cccccggcct tcaggatcgc caaaacacca accaccattg
     1021 ccaagccgcg tttcaggcag atcgccaccg gctggtccgg cttgacccca aacccgatca
     1081 gatgatgcgc cagccggttg gcccgtgcgt tgagttcgcc atagctcagt ctctcgttct
     1141 cataaaccgc agccaacgcc ttcggcgcct tgtgcgcctg cgcctcgaac agctcatgga
     1201 tgtaccgctc cgaccgataa ggcgtcgccg tccgattcaa ttcttccaat agatatttgc
     1261 gttcgtctgc cgggagaata tccgtgcggc cgaccggctg ccccgcatcg gccatcacac
     1321 cgtctaacaa agtctccaaa tgctgcgtca tgcggccgat ctgcctcggc gcaaatcggc
     1381 tggcatcaaa atgccagcgg aagctcccat ccagagcgca aacctcaaac gtcagcaaat
     1441 cgccgcataa ggctggacca gctttgtgac tcgtcatcag atcgccggcc acggaacagc
     1501 tctgtgtcgt gattgtgatg ccaatcggcc agggacggtg cgagtgtagc gcctccacac
     1561 ctcgcaactc cgggcaacgc gcgataagat cccgggcaaa gctaccgtgc gccctcagct
     1621 gagccaattc ggccgctact gttttgcgca cttcttcaaa atcattagcg cgctcaatcg
     1681 tcacttccat cggcacgaca gaagagatca acacctccat cactttggag gcagcttgcg
     1741 aaccatccga tgcaggcgtc catcccagct gaagctctct ttctccggtg atgcgggcga
     1801 gatagatcag ccaagccgtt gccaagtatt ccgagcgatc gcgtggggac agtttagcca
     1861 aagcacttgg agtgaaccac gaactcgact gccattcggg cggcgccgcg gccacggacg
     1921 atgacaggaa gggaggacgc aatctcctaa actgcccgag ccgctgtcgc caaaaatcct
     1981 ccagaggcgc cagcatttcg tgggcggcag ttatgctccg cgcctgttca tcgctcaaga
     2041 tcggaaggcg actaccttca tccacattga agtgcctggc gagggctcgc gcgtccagct
     2101 tctgcccatc gggttcctca aagtagactt cgacatcctc ggtgcccgtc gccacacgcc
     2161 aatggctcgc gtggacttca atcagggagc ctgccgggcg gcccgcactt cgagccaaca
     2221 ccttcaagtt cctgacttcg acggcctgat cgcctataag aaccttgggc agacacattg
     2281 gattaagatc atgcggccca aagcctaggg cccgggtcat cgccgatatc tcttgcgcgg
     2341 attgatccca tcgcagacag cctgcggagt ctgggcgtcg atgtctcgga aagtagcttc
     2401 tgtccaccag tgcctgcgga tgggctaaaa gctccccgtt gtggaggcca gttaagagct
     2461 cgcggaagcc ttcgaccgcg gcttcatggc atttgagatt cagggtcagt gccgtatcgg
     2521 tgggcgcaat caacacctgg cgctgaacca cgatgtcacc ggtatcaata ccgtcatcga
     2581 tcaagtgcca cgtgatggca tattcggtct cacgcgccag cagcgcccag gacgtcacgt
     2641 gcgttcccgc atatcgcggc aatggaccgt tgtggtaatt aaaagcacct cgacgaaccc
     2701 actccaatac atccgccggc agtatgaacg gattggcaac tgaaaaaatg aaatctaccg
     2761 gcgcggcctt caaaaaagaa gagagctctt caacgcttgc tatagacggg atgttcgagc
     2821 gaacagccca atcgcggaat acgccgtcag cacacaaggc tgcaccaatg acgtggccca
     2881 tctcaattgc cagctgcaca catctgatag cgagcgtacc actgccgaca acgacggcag
     2941 aggagatcga tcgcgcaggt aacctgtcct gatcgcctgg ttggcagacg ctcccgcgcg
     3001 ccggagatac ccgatacgac atcttcaccg ctcctgcagt caatccatca agctgggcat
     3061 tcccaccatg ggcgtcgcgc gacgaagcga ctcaaatcag ccacactgtt cgaatttgct
     3121 tgggataact gcgcccgccg tcgcttgcgc aatatagggg gtattggcgg tgccgaagct
     3181 cttggacgca gccaagatct tcccgatgtc gcgggcaggc cgcacgcctc agacatcgtc
     3241 tccggcagaa tcgcaactgc cattttagcc tggtctgagt agagatcatc ggacgacagc
     3301 ccctccgtca acgcgccttc atagaggaga ctacgcatgt actgtgccaa aggaggaatc
     3361 gttccttctc agtatgctgg ccctaacact gctatgtcac ttatccgacc tcgtcggaca
     3421 tcgtaccaat tgagcgcgct atcaatcggc ccaaggcttc tggaatctcg cctgatgtgt
     3481 ttcgggcaaa gaaaagagga gcctagaacg tcaaagagat ttttccgcgg cgcaccggct
     3541 tttcaggtgt gactctcttg aaattccaat agtgcgtgat cgaggccagt gactttcgca
     3601 gtggacgcct agaggtcgtg ctcgttgatc gggggtcaca atccagcggc tgcgaagtag
     3661 ttggcgcgtt ggcgcatgcc tgtggctcga agagtttgac gatttgccaa ctccacaggg
     3721 cgatgaaccg atccgggttt gccggaggct ccaaatcctg agaggatgga gccatgacaa
     3781 gcaagtggcg gcgggacgtc gattgcggcc aagatcggct gcacaccgga gacgctgcat
     3841 gactgggcca agaaggcgga agtcgataac gggcagcggt cggcgttccg accgagacgc
     3901 tgaaggcgct gcaacgggag aaccgcgagc ttaagcaggc caagtagatc ctgcgcaagg
     3961 cacgcgccta tgttgcgatg gcggggctcg accgccgtgt ccaagcgatg atcgccttca
     4021 ttgacgatca tcatggagcg caggtgggcg agccgatcca gggtcttgcc gagcccccct
     4081 tcggcctacc atgccgatcg agccaagctg tcagcgcgcg cccggcggca cgcggcgacg
     4141 aagatcgacg ttcggcgcgc cttcaatcag acttctccgt gtacggcgtg cgcaaggtcc
     4201 caaggtctgg cgccagctca agcgcagaga tcttccatat cgtgcgttcc acagtctcgc
     4261 cattaatgcg ggacatgggt ttgcaagaaa ccatccgcgg caagcccgtc aagaccagca
     4321 gcgacaaggc ggcggcttgc cagcaggatt acgtcgaccg ccagttccag tcgtcacgac
     4381 cttggcactc cgatttcacc tatctcgcga cctggaccgg ctccgtgtac gtcgcctttg
     4441 tcatcggcgc ctatgctcga agcatcgtgg gctggcgggc ctagcgcacg acaagcgccg
     4501 gcttcgtgct cgatgcgctg gactggagca ggccctgcgg cggccggtac gtcgcggggg
     4561 cttgtgcacc atagcgacag gggccgccag aacctctcga tcacatacac cgagtgctgc
     4621 tgaagtagga gcggagctat ctatcggcag tgtcggagat cctatgacga cgctctcacc
     4681 agaaccatca acggccttca caaggccgag gtgatccacg gccgggtcat ggcgaagctt
     4741 cgaggctttc gaatttccac cctagaatgg gtcgattgct caacaaccga cggctcctgg
     4801 agctcatcgc caacattccc tcgtgccggg acaaccagcc atggcagcat aactcaaacc
     4861 aaatggcctc gagggcaagc ccgggggtgg ttcaccttac tcaatatgcc gagcctgccg
     4921 ggtcgttgag cttgtggcgc tcggttccgt tgaggggcgg gttgaagata ctaacgagga
     4981 tcagatcctt gtctcgcccc ccgcgcagaa gatgcttgtc atgcttgtct agcacataca
     5041 tgtcgccctt gcgaatgggg aagacattgc cgtccatgtc ctcaacctcg ccctctccgg
     5101 cgatgcagta gcaggcttcg agatgattac gatattgcag aagcgagatg gtgttagcgc
     5161 gcactacggt gtggcagatg ctaaagccca tgccgtcctt agccgtcagg aggcggtggc
     5221 tagtaccatt gccccaatcg acgaagtgat cggtcgcttc aatatcgtgc aggctacgca
     5281 caatcatctt gtttgattcc atgaatacag gtgcaagtca ctattgtcga aacgcgccat
     5341 tgttctgacc tagaagcgcg gcttctgcgc tcccgaagcg gaaagcctag ggctatttgg
     5401 acggggcagg ccgtcgagag cctgccaatc catgtcctcc gcggccactc gcccattcct
     5461 gatacggcgg cgtctgacct cgccgcgaag ccgtagccca atcatgagac gagagacctc
     5521 gccaccatgg cggcgcggcg gccgcggtgg catcaggatc gattgagcaa gtttcatccg
     5581 aactcttaga agtgagctgc tagattgtta gggtcgtgac ggccctctct caagcaagcg
     5641 atgtgccaac gacattctga aaacactcct gaaaaaacaa tgcgcctctc gccgcgctag
     5701 ctgggatctg ccgtcacgct tgcgacaccg atgtcttgaa tgaaacgcag ctcaacacag
     5761 gaccgcggcg gggcaagctt cgctgaaatg tggacaatgg tgataaatga tccggaaact
     5821 ctcaaattcg ctgctgacat tcgctgttcg tacagcagcc aactggcggg ccggtcgaaa
     5881 cgagtcggcg tcacatcaac cgctattccg aagcaatctg tcacagatct aggcaatacc
     5941 tggcaggctc acggtcggat cacctatgat aaccagcgtc tgcctgtcca tcgccactaa
     6001 ctggcggtac aatgcgaaat cgcgcatact tggctcgccg gcgtttattc cagctatcgc
     6061 atcttgccaa gccgcataaa acgctccggc ctcgcgatag accttctgca acgcccaacc
     6121 gagcggattg cgctcgtaac gtaagtaaag tctatcgtaa agcgctgagc aaaggacatg
     6181 cgtgagcacc tgcttgttgg ccggatcccg cagggtccag tcgaatgtgg gctcgacatg
     6241 cccgacaaat gcgcgcagcg gcttttccgc accaagcaat gcacgcggca ccggcgcgat
     6301 cgcggcacct gcgacggtcg caatcctgtt cagaaccgta cttattgtcc cagattcagg
     6361 caaaagtccc ttgtaccgtg agaccgaatc cgatcccgcc gaacagcacg catgcgagta
     6421 ccagatcgca ccagacggct gccacatctg caattgcgtg ccgtcgacta ccttgtggtc
     6481 gatatcgacc ggggcaccga tccacgattt caagcgaacg tcgtcgtcga gcgggccagt
     6541 catgccgtga cttgtcgtga tcaagagtgc tggcgacaat tccgtaagtg aggcaaccaa
     6601 acttgatcta ttggccgacg tgtccgcaat ccttcggcgc cgaaccagat cgttgttgcc
     6661 gtcaatcttc tcccagagtt ttccggcgac cgcacgagcc atcaaccatg taatgtcgtt
     6721 ctttccgaga tcgacgctcc atacgacggg cgccttcgga tcggaaaatt gaccctgcca
     6781 gtcgtcgatc agcgcatcga catagtgatc gagcgcagta tcgaccaagt ccaggcgccc
     6841 gacgaagagc gacatctgca gcgcatattg aagcgcccag ggaagttgag tgggcgaacc
     6901 atacagcagc aaatattgcg gaatacaccc cttaccggtt ccaaccttag gggcgagggt
     6961 cgacaagtcg tgaaagttgc cgtccggata atagcgacgc aaaaagcctt gccccaaact
     7021 gctgcgccaa cgcaataccg gcgcgtttga ccgcttctcg atcagtcgtc tgattgcggg
     7081 cggcgcatct accgcggtcg acctgtccga gtttgataaa acatcattgt ccagcagaac
     7141 aacgccccag cctattcgtg gatcgctcca gttgcgttca tcaatctctt gcggtgctgc
     7201 cagttgcgct gctgacagcg caggtaccag cctttgcgac tgagcccaag gcgttcgcga
     7261 tggcaaaaca tcgcccgccg tactctcgcc gttccatgcg ttgatctgta catccttggg
     7321 gcggttgatt tcgtcggtca tggtgtggca aattcgccga agcggttcgg cctgaagtgc
     7381 ggcggaaccg agggtggatt gtcgagcaag gccgcgatct ggtcgcgcac ttcctcaggc
     7441 gtttcctcct ccatccgccg cagagttctc gcaacggcga gcaccctact ggcgacgtcg
     7501 gccggaagtt gcaacgctag gaacggcttg tgagatgcct catagaggac cggcaacaac
     7561 catcgcccaa aacctccggg caccgcgcag cagtgatcgt gaatgattcg acgagcgggg
     7621 atcacagctg gggcgaaatc gaatatcacc ggaccggctg ccggctcagg agtgagtttc
     7681 gacccaacga tccgaaacag ctctctgtaa aacgcttggg taaacgtcgt ggcggcggct
     7741 gtatcaatcg gctcggccat accgacggta tagggacaac ccttcctggc cacggtgagc
     7801 gccatcgaga acagctgatg aaggacctcg gcaccggaac aactattaaa caccgtaacc
     7861 caaacagagg aattcagtgc aagggcctca ctcaaagctg tgacggagag gaagatcgac
     7921 gaggaatcgg cattgccgtt tgcctcattc gcttcgtgat cgctcgtcgt ggcgatcgac
     7981 aatccctgaa tgccaagccg atcgatgccg tgacagaaga aatgcacaaa ctgtaccgga
     8041 gcgtctctca gaaggttcgc tacttgggtg gccgtggaag gcatctgctc gatggtgatg
     8101 ccggtgttgt gcagcggccc cactgccgtc ttgtgtcgat actcatccag caacgcctgc
     8161 tcggctagaa agacggtgca ctcgatctcg aggccgttct gtttgctttc gacgatctga
     8221 tcgcagatcg ttttcatttc tcggtcggcc ttgatcccgg cggcggacag gaaggcaaac
     8281 atgcgcagcg gacgggtgaa cgccttcagc gtcgaaccga tcctggccgg ggccagccta
     8341 ctaacggtgc acaattcgct catggcaagg aagcgtggtt ctgcaccgcc atggatcgct
     8401 tcccagcgga accgttccgc atccggtgcc ttcatgagaa atctcaaggc cgccctttga
     8461 ggaacctgct gcccaaacat atgggtcagc tccgctttaa tcgccgggtg gtccgacaag
     8521 gctttgtgaa ccgcggcgcc gtaagcggtg acatttgtct ccgtatcgag cggcggcatt
     8581 gcttctgcat cgaggtcgag cgatctaaac tcgagcgcat agggatgatt gctttgactc
     8641 tcgaggcaga caatcatgtc gttgttgccg cctccgataa tcgaaacgat cgtgtcgcgc
     8701 atatgtcagc cgccgagctt gcggagatag ttgcctacca ccttgtgaat ttgctcaaga
     8761 gtgtcgtccg aacccgcgat tgattcgacg ctttcatcgg gagtaacctg ggtccgcgcg
     8821 ttatccgagg acgaaagcaa gacgtccgat gcgttgcgac gtagtcgttc aagtgccgaa
     8881 aattcacatt ggcgctgcag cgacgttgcc caactcggcg cctgcttcat ctcatagtcc
     8941 gggatgccct gagtatcaga tgacatgtgg ggcggtgtcc gatctgcgat tgaggcggag
     9001 tggaaaatgg atgcattggc cttcaaggct ggaagcggcg aggatatatg gaggctctcg
     9061 tacgcatcga catagttggg cgggcaatat agaaaaccat cgaccataga aggcgctggc
     9121 gcagagttag ctgcgaacag gaacgaacag gcggctcgca aggatgcaat ttgctgggaa
     9181 ctgccgagcg gttgatagag caccgcagtg ggacgggtgt gcgcgagtgc gtcagcggcc
     9241 aaggccaaca ttggtctggc ggcgcccgaa ggcgaatttg aaaacaatgc cgcccaagcg
     9301 ccggctcgtg ttacgattgc ggcgagatcc atcgcatcga catatgagta agactcatat
     9361 ttctcattcg gcgcaatcga attagacatc ctgagggcgg gtccgaattc agtcatgccg
     9421 gaattgcaga cgaagaagat cgcatcgagg cttcgcgtgc cgagtgctgc cttcatccag
     9481 acccaccaga gcgattggaa cggtggctcg atgggcccct ttgagaatac tgccgcgctg
     9541 gtgggcgcaa acatggggtc atggattctc aaccgtttgt catagccatc cttttccaat
     9601 aaccgatgcc aaaagctggc ggtaaacaag tgcaccctgc tttgggctcg cggagaagcg
     9661 gataagatgg tctctacgat ctggttgagg agcgtttgaa cgttggtcag aggcgcgctt
     9721 cgatcagggt cgaaccaaat cgcaagttcg agaacatcac ggtcttcgca tgggcgttcg
     9781 agaagatcgg gaaagcgcag caccgggcgt tccaaggttt cggtcagcgc cctctcccac
     9841 gggagtacgg atacatagcc gtggggcttg gcaaaacgaa gccagagcgg cagatccttg
     9901 gcatcgcctt tcaggctgtt tttgataccg ctggtgatct gcggccacaa attcagatcc
     9961 ggcgccgcat cggtctcgat gctactaggt acgcccagct ctcgagcagg aatctgccag
    10021 ctctcagtcg accccgccgt tccaacgccg cggatcaata gcaattcaat ctgagggctg
    10081 gcttcccaga acgtcagcgt gacctgcaat atgatcaacg gtggagatga tgactgtccg
    10141 gacatgaacg ctctcgtcga ctaaggccgt tcgtcgtttc aacgcgacat ctgctcacgc
    10201 agtaaccagg cggtcgaagg atttacgatg ccgccatggg catcgatccg attgcctgcc
    10261 gagccgtcga agccgacaat gcgcgta
//
