Select genomic region:
Overview
3.1
4.1
4.2
11.1
11.2
11.3
12.1
15.1
31.1
40.1
46.1
59.1
60.1

### Identified secondary metabolite regions using strictness 'relaxed'

c00003_NZ_JARF.. (original name was: NZ_JARFMK010000012.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | hserlactone | 209,858 | 230,529 |

c00004_NZ_JARF.. (original name was: NZ_JARFMK010000013.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 4.1 | ectoine | 1 | 10,287 | rhizomide A / rhizomide B / rhizomide C | NRP | 100%
Region 4.2 | RiPP-like | 108,499 | 119,419 |

c00011_NZ_JARF.. (original name was: NZ_JARFMK010000001.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 11.1 | terpene | 142,521 | 167,507 | malleobactin A / malleobactin B / malleobactin C / malleobactin D | NRP:NRP siderophore | 7%
Region 11.2 | redox-cofactor | 903,461 | 925,742 |
Region 11.3 | RiPP-like,NRPS | 1,224,258 | 1,273,748 |

c00012_NZ_JARF.. (original name was: NZ_JARFMK010000020.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 12.1 | phosphonate | 1 | 30,965 |

c00015_NZ_JARF.. (original name was: NZ_JARFMK010000023.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 15.1 | hserlactone | 63,026 | 78,654 |

c00031_NZ_JARF.. (original name was: NZ_JARFMK010000038.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 31.1 | NRPS-like | 1 | 15,246 | luminmide | NRP | 100%

c00040_NZ_JARF.. (original name was: NZ_JARFMK010000046.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 40.1 | NRPS | 1 | 4,208 | rhizomide A / rhizomide B / rhizomide C | NRP | 100%

c00046_NZ_JARF.. (original name was: NZ_JARFMK010000051.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 46.1 | NRPS | 1 | 2,354 | luminmide | NRP | 100%

c00059_NZ_JARF.. (original name was: NZ_JARFMK010000007.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 59.1 | terpene | 91,975 | 112,838 |

c00060_NZ_JARF.. (original name was: NZ_JARFMK010000008.1)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 60.1 | NRPS | 252,570 | 325,269 | crochelin A | NRP + Polyketide | 23%

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 3.1 | hserlactone | 209,858 | 230,529 |
Region 4.1 | ectoine | 1 | 10,287 | rhizomide A / rhizomide B / rhizomide C | NRP | 100%
Region 4.2 | RiPP-like | 108,499 | 119,419 |
Region 11.1 | terpene | 142,521 | 167,507 | malleobactin A / malleobactin B / malleobactin C / malleobactin D | NRP:NRP siderophore | 7%
Region 11.2 | redox-cofactor | 903,461 | 925,742 |
Region 11.3 | RiPP-like,NRPS | 1,224,258 | 1,273,748 |
Region 12.1 | phosphonate | 1 | 30,965 |
Region 15.1 | hserlactone | 63,026 | 78,654 |
Region 31.1 | NRPS-like | 1 | 15,246 | luminmide | NRP | 100%
Region 40.1 | NRPS | 1 | 4,208 | rhizomide A / rhizomide B / rhizomide C | NRP | 100%
Region 46.1 | NRPS | 1 | 2,354 | luminmide | NRP | 100%
Region 59.1 | terpene | 91,975 | 112,838 |
Region 60.1 | NRPS | 252,570 | 325,269 | crochelin A | NRP + Polyketide | 23%

No secondary metabolite regions were found in these records:
  c00001_NZ_JARF.. (original name was: NZ_JARFMK010000010.1)
  c00002_NZ_JARF.. (original name was: NZ_JARFMK010000011.1)
  c00005_NZ_JARF.. (original name was: NZ_JARFMK010000014.1)
  c00006_NZ_JARF.. (original name was: NZ_JARFMK010000015.1)
  c00007_NZ_JARF.. (original name was: NZ_JARFMK010000016.1)
  c00008_NZ_JARF.. (original name was: NZ_JARFMK010000017.1)
  c00009_NZ_JARF.. (original name was: NZ_JARFMK010000018.1)
  c00010_NZ_JARF.. (original name was: NZ_JARFMK010000019.1)
  c00013_NZ_JARF.. (original name was: NZ_JARFMK010000021.1)
  c00014_NZ_JARF.. (original name was: NZ_JARFMK010000022.1)
  c00016_NZ_JARF.. (original name was: NZ_JARFMK010000024.1)
  c00017_NZ_JARF.. (original name was: NZ_JARFMK010000025.1)
  c00018_NZ_JARF.. (original name was: NZ_JARFMK010000026.1)
  c00019_NZ_JARF.. (original name was: NZ_JARFMK010000027.1)
  c00020_NZ_JARF.. (original name was: NZ_JARFMK010000028.1)
  c00021_NZ_JARF.. (original name was: NZ_JARFMK010000029.1)
  c00022_NZ_JARF.. (original name was: NZ_JARFMK010000002.1)
  c00023_NZ_JARF.. (original name was: NZ_JARFMK010000030.1)
  c00024_NZ_JARF.. (original name was: NZ_JARFMK010000031.1)
  c00025_NZ_JARF.. (original name was: NZ_JARFMK010000032.1)
  c00026_NZ_JARF.. (original name was: NZ_JARFMK010000033.1)
  c00027_NZ_JARF.. (original name was: NZ_JARFMK010000034.1)
  c00028_NZ_JARF.. (original name was: NZ_JARFMK010000035.1)
  c00029_NZ_JARF.. (original name was: NZ_JARFMK010000036.1)
  c00030_NZ_JARF.. (original name was: NZ_JARFMK010000037.1)
  c00032_NZ_JARF.. (original name was: NZ_JARFMK010000039.1)
  c00033_NZ_JARF.. (original name was: NZ_JARFMK010000003.1)
  c00034_NZ_JARF.. (original name was: NZ_JARFMK010000040.1)
  c00035_NZ_JARF.. (original name was: NZ_JARFMK010000041.1)
  c00036_NZ_JARF.. (original name was: NZ_JARFMK010000042.1)
  c00037_NZ_JARF.. (original name was: NZ_JARFMK010000043.1)
  c00038_NZ_JARF.. (original name was: NZ_JARFMK010000044.1)
  c00039_NZ_JARF.. (original name was: NZ_JARFMK010000045.1)
  c00041_NZ_JARF.. (original name was: NZ_JARFMK010000047.1)
  c00042_NZ_JARF.. (original name was: NZ_JARFMK010000048.1)
  c00043_NZ_JARF.. (original name was: NZ_JARFMK010000049.1)
  c00044_NZ_JARF.. (original name was: NZ_JARFMK010000004.1)
  c00045_NZ_JARF.. (original name was: NZ_JARFMK010000050.1)
  c00047_NZ_JARF.. (original name was: NZ_JARFMK010000052.1)
  c00048_NZ_JARF.. (original name was: NZ_JARFMK010000053.1)
  c00049_NZ_JARF.. (original name was: NZ_JARFMK010000054.1)
  c00050_NZ_JARF.. (original name was: NZ_JARFMK010000055.1)
  c00051_NZ_JARF.. (original name was: NZ_JARFMK010000056.1)
  c00052_NZ_JARF.. (original name was: NZ_JARFMK010000057.1)
  c00053_NZ_JARF.. (original name was: NZ_JARFMK010000058.1)
  c00054_NZ_JARF.. (original name was: NZ_JARFMK010000059.1)
  c00055_NZ_JARF.. (original name was: NZ_JARFMK010000005.1)
  c00056_NZ_JARF.. (original name was: NZ_JARFMK010000060.1)
  c00057_NZ_JARF.. (original name was: NZ_JARFMK010000061.1)
  c00058_NZ_JARF.. (original name was: NZ_JARFMK010000006.1)
  c00061_NZ_JARF.. (original name was: NZ_JARFMK010000009.1)

Compact view
c00003_NZ_JARF.. - Region 1 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 209,858 - 230,529 nt. (total: 20,672 nt) Show pHMM detection rules used
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000519.1 |  | 0.17 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0001579.1 |  | 0.16 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0000563.1 |  | 0.16 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0001660.1 |  | 0.16 | RiPP | mathermycin | Marinactinospora thermotolerans
BGC0000527.1 |  | 0.16 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0001551.1 |  | 0.16 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000551.1 |  | 0.16 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0000502.1 |  | 0.16 | RiPP | cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7 | Bacillus cereus
BGC0000592.1 |  | 0.16 | RiPP | microviridin B | Microcystis aeruginosa NIES-298
BGC0000600.1 |  | 0.16 | RiPP | thurincin H | Bacillus thuringiensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000519.1 |  | 0.47 | RiPP | labyrinthopeptin A2, labyrinthopeptin A1, labyrinthopeptin A3 | Actinomadura namibiensis
BGC0001579.1 |  | 0.47 | RiPP | duramycin | Streptomyces cinnamoneus
BGC0000563.1 |  | 0.47 | RiPP | venezuelin | Streptomyces venezuelae ATCC 10712
BGC0001660.1 |  | 0.47 | RiPP | mathermycin | Marinactinospora thermotolerans
BGC0000527.1 |  | 0.47 | RiPP | mersacidin | Bacillus sp. HIL-Y85/54728
BGC0001551.1 |  | 0.47 | RiPP | citrulassin E | Streptomyces glaucescens
BGC0000551.1 |  | 0.47 | RiPP | SapB | Streptomyces coelicolor A3(2)
BGC0000502.1 |  | 0.47 | RiPP | cerecidin, cerecidin A1, cerecidin A2, cerecidin A3, cerecidin A4, cerecidin A5, cerecidin A6, cerecidin A7 | Bacillus cereus
BGC0000592.1 |  | 0.46 | RiPP | microviridin B | Microcystis aeruginosa NIES-298
BGC0000600.1 |  | 0.46 | RiPP | thurincin H | Bacillus thuringiensis

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00004_NZ_JARF.. - Region 1 - ectoine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 10,287 nt. (total: 10,287 nt) Show pHMM detection rules used
Region on contig edge.
ectoine: ectoine_synt

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | ectoine | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.27 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000856.1 |  | 0.27 | Other | ectoine | Methylophaga thalassica
BGC0000852.1 |  | 0.27 | Other | ectoine | Sporosarcina pasteurii
BGC0000858.1 |  | 0.27 | Other | ectoine | Methylobacter marinus
BGC0000855.1 |  | 0.27 | Other | ectoine | Methylomicrobium kenyense
BGC0000854.1 |  | 0.21 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.21 | Other | ectoine | Methylophaga alcalica
BGC0000860.1 |  | 0.20 | Other | ectoine | Methylarcula marina
BGC0000427.1 |  | 0.17 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001758.1 |  | 0.16 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000859.1 |  | 0.61 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000856.1 |  | 0.61 | Other | ectoine | Methylophaga thalassica
BGC0000852.1 |  | 0.60 | Other | ectoine | Sporosarcina pasteurii
BGC0000858.1 |  | 0.60 | Other | ectoine | Methylobacter marinus
BGC0000855.1 |  | 0.60 | Other | ectoine | Methylomicrobium kenyense
BGC0000854.1 |  | 0.54 | Other | ectoine | Methylomicrobium alcaliphilum 20Z
BGC0000857.1 |  | 0.53 | Other | ectoine | Methylophaga alcalica
BGC0000860.1 |  | 0.52 | Other | ectoine | Methylarcula marina
BGC0000427.1 |  | 0.48 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001758.1 |  | 0.47 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00004_NZ_JARF.. - Region 2 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 108,499 - 119,419 nt. (total: 10,921 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001486.1 |  | 0.20 | RiPP | 3-thiaglutamate | Pseudomonas syringae pv. maculicola str. ES4326
BGC0002027.1 |  | 0.20 | RiPP | TglA-thiaGlu | Pseudomonas syringae pv. maculicola str. ES4326
BGC0001607.1 |  | 0.13 | Other | gilvusmycin | Streptomyces sp. NRRL B-1347
BGC0000608.1 |  | 0.12 | RiPP | nocathiacin | Actinokineospora fastidiosa
BGC0000613.1 |  | 0.09 | RiPP | thiomuracin A | Nonomuraea sp. Bp3714-39
BGC0001860.1 |  | 0.09 | RiPP | thiomuracin | Thermobispora bispora DSM 43833
BGC0001707.1 |  | 0.08 | RiPP | nosiheptide | Streptomyces sp.
BGC0000604.1 |  | 0.07 | RiPP | GE2270A | Nonomuraea sp. WU8817
BGC0001155.1 |  | 0.06 | RiPP | GE2270 | Planobispora rosea
BGC0000610.1 |  | 0.06 | RiPP | nosiheptide | Streptomyces actuosus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001486.1 |  | 0.52 | RiPP | 3-thiaglutamate | Pseudomonas syringae pv. maculicola str. ES4326
BGC0002027.1 |  | 0.52 | RiPP | TglA-thiaGlu | Pseudomonas syringae pv. maculicola str. ES4326
BGC0001607.1 |  | 0.41 | Other | gilvusmycin | Streptomyces sp. NRRL B-1347
BGC0000608.1 |  | 0.40 | RiPP | nocathiacin | Actinokineospora fastidiosa
BGC0000613.1 |  | 0.33 | RiPP | thiomuracin A | Nonomuraea sp. Bp3714-39
BGC0001860.1 |  | 0.33 | RiPP | thiomuracin | Thermobispora bispora DSM 43833
BGC0001707.1 |  | 0.31 | RiPP | nosiheptide | Streptomyces sp.
BGC0000604.1 |  | 0.28 | RiPP | GE2270A | Nonomuraea sp. WU8817
BGC0001155.1 |  | 0.27 | RiPP | GE2270 | Planobispora rosea
BGC0000610.1 |  | 0.26 | RiPP | nosiheptide | Streptomyces actuosus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
c00011_NZ_JARF.. - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 142,521 - 167,507 nt. (total: 24,987 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000648.1 |  | 0.34 | Terpene | carotenoid | Myxococcus xanthus
BGC0000646.1 |  | 0.24 | Terpene | β-carotein | uncultured bacterium
BGC0000656.1 |  | 0.24 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000859.1 |  | 0.24 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000853.1 |  | 0.24 | Other | ectoine | Streptomyces anulatus
BGC0000630.1 |  | 0.23 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000856.1 |  | 0.23 | Other | ectoine | Methylophaga thalassica
BGC0000640.1 |  | 0.23 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000641.1 |  | 0.21 | Terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0000639.1 |  | 0.21 | Terpene | carotenoid | Enterobacteriaceae bacterium DC260

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000648.1 |  | 0.67 | Terpene | carotenoid | Myxococcus xanthus
BGC0000646.1 |  | 0.58 | Terpene | β-carotein | uncultured bacterium
BGC0000656.1 |  | 0.57 | Terpene | zeaxanthin | Xanthobacter autotrophicus Py2
BGC0000859.1 |  | 0.57 | Other | ectoine | Methylomicrobium alcaliphilum
BGC0000853.1 |  | 0.57 | Other | ectoine | Streptomyces anulatus
BGC0000630.1 |  | 0.57 | Terpene | (2R,3S,3'S)-2-hydroxyastaxanthin | Paracoccus haeundaensis
BGC0000856.1 |  | 0.57 | Other | ectoine | Methylophaga thalassica
BGC0000640.1 |  | 0.56 | Terpene | carotenoid | Enterobacteriaceae bacterium DC404
BGC0000641.1 |  | 0.54 | Terpene | carotenoid | Enterobacteriaceae bacterium DC416
BGC0000639.1 |  | 0.53 | Terpene | carotenoid | Enterobacteriaceae bacterium DC260

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00011_NZ_JARF.. - Region 2 - redox-cofactor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 903,461 - 925,742 nt. (total: 22,282 nt) Show pHMM detection rules used
redox-cofactor: (cds(PF04055 and (TIGR04085 or SPASM)) and (TIGR02111 or TIGR03966) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | redox-cofactor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001576.1 |  | 0.17 | RiPP | divamide A | Prochloron didemni
BGC0000929.1 |  | 0.14 | Other | xanthothricin | Burkholderia glumae
BGC0001959.1 |  | 0.14 | Other | taylorflavin A, taylorflavin B | Streptomyces hiroshimensis
BGC0001973.1 |  | 0.14 | Other | fervenulin | Streptomyces hiroshimensis
BGC0001972.1 |  | 0.14 | Other | toxoflavin, fervenulin | Streptomyces hiroshimensis
BGC0001521.1 |  | 0.14 | NRP | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0000906.1 |  | 0.13 | Other | heme D1 | Heliophilum fasciatum
BGC0001100.1 |  | 0.10 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0001940.1 |  | 0.09 | Polyketide | pyxidicycline A, pyxidicycline B | Pyxidicoccus fallax
BGC0000111.1 |  | 0.09 | Polyketide | neocarzilin A, neocarzilin B | Streptomyces carzinostaticus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001576.1 |  | 0.48 | RiPP | divamide A | Prochloron didemni
BGC0000929.1 |  | 0.44 | Other | xanthothricin | Burkholderia glumae
BGC0001959.1 |  | 0.44 | Other | taylorflavin A, taylorflavin B | Streptomyces hiroshimensis
BGC0001973.1 |  | 0.43 | Other | fervenulin | Streptomyces hiroshimensis
BGC0001972.1 |  | 0.43 | Other | toxoflavin, fervenulin | Streptomyces hiroshimensis
BGC0001521.1 |  | 0.43 | NRP | auriculamide | Herpetosiphon aurantiacus DSM 785
BGC0000906.1 |  | 0.42 | Other | heme D1 | Heliophilum fasciatum
BGC0001100.1 |  | 0.35 | NRP, Polyketide | lankacidin C | Streptomyces rochei
BGC0001940.1 |  | 0.34 | Polyketide | pyxidicycline A, pyxidicycline B | Pyxidicoccus fallax
BGC0000111.1 |  | 0.33 | Polyketide | neocarzilin A, neocarzilin B | Streptomyces carzinostaticus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00011_NZ_JARF.. - Region 3 - NRPS,RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,224,258 - 1,273,748 nt. (total: 49,491 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0000457.1 |  |  | 0.32 | NRP | vicibactin | Rhizobium etli CFN 42
BGC0001197.1 |  |  | 0.30 | Polyketide | frankiamicin | Frankia sp. EAN1pec
BGC0001687.1 |  |  | 0.28 | Other | N-tetradecanoyl tyrosine | uncultured bacterium CSL12
BGC0000204.1 |  |  | 0.28 | Polyketide | benastatin A, benastatin B, BE-43767, TAN1532B | Streptomyces sp. A2991200
BGC0001479.1 |  |  | 0.27 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001820.1 |  |  | 0.27 | NRP | verticillin | Gliocladium sp.
BGC0001585.1 |  |  | 0.27 | Alkaloid | melinacidin IV | Escovopsis weberi
BGC0000321.1 |  |  | 0.26 | NRP | chaetocin | Collariella virescens
BGC0000979.1 |  |  | 0.26 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 10E9
BGC0000980.1 |  |  | 0.26 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 22D11

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000457.1 |  | 0.65 | NRP | vicibactin | Rhizobium etli CFN 42
BGC0001479.1 |  | 0.61 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001820.1 |  | 0.60 | NRP | verticillin | Gliocladium sp.
BGC0001585.1 |  | 0.60 | Alkaloid | melinacidin IV | Escovopsis weberi
BGC0000321.1 |  | 0.60 | NRP | chaetocin | Collariella virescens
BGC0000979.1 |  | 0.59 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 10E9
BGC0000980.1 |  | 0.59 | NRP, Polyketide | cylindrospermopsin | Aphanizomenon sp. 22D11
BGC0000342.1 |  | 0.59 | NRP | enniatin | Fusarium equiseti
BGC0001132.1 |  | 0.59 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001128.1 |  | 0.59 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 3, location 1224257 - 1273748:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X - X)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 5, location 1227304 - 1273748:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X - X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg11_1157: X - X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (34..430): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      ahSTrAtsqK
    Nearest Stachelhaus code:
      bht
    Stachelhaus code match:
      40% (weak)
  AMP-binding (1089..1500): X
  NRPSPredictor2: asp, asn, glu, gln, aad
  SVM prediction details:
    Predicted physicochemical class:
      N/A
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      ViWeItadDK
    Nearest Stachelhaus code:
      ala-b
    Stachelhaus code match:
      50% (weak)

c00012_NZ_JARF.. - Region 1 - phosphonate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 30,965 nt. (total: 30,965 nt) Show pHMM detection rules used
Region on contig edge.
phosphonate: phosphonates

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | phosphonate | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.27 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000897.1 |  | 0.26 | Other | dehydrophos | Streptomyces luridus
BGC0000937.1 |  | 0.18 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0000904.1 |  | 0.16 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001485.1 |  | 0.16 | Other | 3-demethylchuangxinmycin | Actinoplanes tsinanensis
BGC0001546.1 |  | 0.16 | Alkaloid | chuangxinmycin | Actinoplanes tsinanensis
BGC0001735.1 |  | 0.15 | Other | pentostatine, vidarabine | Streptomyces antibioticus
BGC0001411.1 |  | 0.15 | Saccharide | polysaccharide B | Bacteroides fragilis
BGC0001120.1 |  | 0.15 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001374.1 |  | 0.14 | Other | thienodolin | Streptomyces albogriseolus

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001859.1 |  | 0.61 | Other (Phosphonate) | fosfomycin | Pseudomonas syringae
BGC0000897.1 |  | 0.60 | Other | dehydrophos | Streptomyces luridus
BGC0000937.1 |  | 0.49 | Other | fosfazinomycin A | Streptomyces sp. WM6372
BGC0000904.1 |  | 0.47 | Other | FR-900098 | Streptomyces rubellomurinus
BGC0001485.1 |  | 0.46 | Other | 3-demethylchuangxinmycin | Actinoplanes tsinanensis
BGC0001546.1 |  | 0.46 | Alkaloid | chuangxinmycin | Actinoplanes tsinanensis
BGC0001735.1 |  | 0.46 | Other | pentostatine, vidarabine | Streptomyces antibioticus
BGC0001411.1 |  | 0.45 | Saccharide | polysaccharide B | Bacteroides fragilis
BGC0001120.1 |  | 0.44 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0001374.1 |  | 0.44 | Other | thienodolin | Streptomyces albogriseolus

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00015_NZ_JARF.. - Region 1 - hserlactone
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 63,026 - 78,654 nt. (total: 15,629 nt) Show pHMM detection rules used
Region on contig edge.
hserlactone: Autoind_synth

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | hserlactone | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000944.1 |  | 0.11 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0001408.1 |  | 0.09 | Other | xanthoferrin | Xanthomonas oryzae pv. oryzae KACC 10331
BGC0001131.1 |  | 0.08 | NRP | ambactin | Xenorhabdus miraniensis
BGC0000329.1 |  | 0.06 | NRP | corpeptin A, corpeptin B | Pseudomonas corrugata
BGC0001692.1 |  | 0.06 | NRP | nematophin | Xenorhabdus nematophila ATCC 19061
BGC0000417.1 |  | 0.05 | NRP | rhodochelin | Rhodococcus jostii RHA1
BGC0000961.1 |  | 0.04 | NRP, Polyketide | bactobolin | Burkholderia thailandensis E264
BGC0001790.1 |  | 0.04 | NRP | sulfazecin | Pseudomonas acidophila

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000944.1 |  | 0.37 | Other (Non-NRP siderophore) | staphyloferrin A | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0001408.1 |  | 0.33 | Other | xanthoferrin | Xanthomonas oryzae pv. oryzae KACC 10331
BGC0001131.1 |  | 0.31 | NRP | ambactin | Xenorhabdus miraniensis
BGC0000329.1 |  | 0.25 | NRP | corpeptin A, corpeptin B | Pseudomonas corrugata
BGC0001692.1 |  | 0.25 | NRP | nematophin | Xenorhabdus nematophila ATCC 19061
BGC0000417.1 |  | 0.23 | NRP | rhodochelin | Rhodococcus jostii RHA1
BGC0000961.1 |  | 0.20 | NRP, Polyketide | bactobolin | Burkholderia thailandensis E264
BGC0001790.1 |  | 0.18 | NRP | sulfazecin | Pseudomonas acidophila

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00031_NZ_JARF.. - Region 1 - NRPS-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 15,246 nt. (total: 15,246 nt) Show pHMM detection rules used
Region on contig edge.
NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000427.1 |  | 0.22 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001758.1 |  | 0.22 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001844.1 |  | 0.22 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001135.1 |  | 0.22 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001641.1 |  | 0.22 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1 |  | 0.21 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001132.1 |  | 0.21 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001479.1 |  | 0.20 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001128.1 |  | 0.20 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001825.1 |  | 0.19 | NRP | xenematide | Xenorhabdus nematophila AN6/1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000427.1 |  | 0.55 | NRP | shinorine, 4-deoxygadusol, mycosporine glycine | Trichormus variabilis ATCC 29413
BGC0001758.1 |  | 0.55 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001844.1 |  | 0.55 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001135.1 |  | 0.54 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001641.1 |  | 0.54 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001833.1 |  | 0.53 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001132.1 |  | 0.53 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001479.1 |  | 0.53 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001128.1 |  | 0.53 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001825.1 |  | 0.51 | NRP | xenematide | Xenorhabdus nematophila AN6/1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 0 - 15246:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (phe)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg31_1: phe
  Search NORINE for peptide: strict or relaxed
  AMP-binding (1..395): phe
  NRPSPredictor2: phe
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      phe, trp, phg, tyr, bht
    Small clusters prediction:
      phe, trp
    Single AA prediction:
      phe
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWTIAAvCK
    Nearest Stachelhaus code:
      phe
    Stachelhaus code match:
      90% (moderate)

c00040_NZ_JARF.. - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 4,208 nt. (total: 4,208 nt) Show pHMM detection rules used
Region on contig edge.
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001249.1 |  | 0.31 | NRP | dimethylcoprogen | Alternaria alternata
BGC0001479.1 |  | 0.29 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001132.1 |  | 0.28 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001135.1 |  | 0.28 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001128.1 |  | 0.27 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001641.1 |  | 0.26 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000375.1 |  | 0.26 | NRP | indigoidine | Streptomyces chromofuscus
BGC0001844.1 |  | 0.25 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001758.1 |  | 0.25 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001833.1 |  | 0.24 | NRP | icosalide A, icosalide B | Burkholderia gladioli

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001249.1 |  | 0.64 | NRP | dimethylcoprogen | Alternaria alternata
BGC0001479.1 |  | 0.62 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001132.1 |  | 0.61 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001135.1 |  | 0.61 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001128.1 |  | 0.61 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001641.1 |  | 0.60 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0000375.1 |  | 0.59 | NRP | indigoidine | Streptomyces chromofuscus
BGC0001844.1 |  | 0.59 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0001758.1 |  | 0.59 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001833.1 |  | 0.57 | NRP | icosalide A, icosalide B | Burkholderia gladioli

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 0 - 4208:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg40_1: X - ser
  Search NORINE for peptide: strict or relaxed
  AMP-binding (1..390): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      val, leu, ile, abu, iva
    Single AA prediction:
      ile
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAFFLGCtFK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      90% (moderate)
  AMP-binding (1057..1402): ser
  NRPSPredictor2: ser
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      ser, thr, dhpg, hpg
    Small clusters prediction:
      ser
    Single AA prediction:
      ser
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHVSLIDK
    Nearest Stachelhaus code:
      ser
    Stachelhaus code match:
      100% (strong)

c00046_NZ_JARF.. - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 2,354 nt. (total: 2,354 nt) Show pHMM detection rules used
Region on contig edge.
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
Pfam domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001128.1 |  | 0.27 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001641.1 |  | 0.27 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001132.1 |  | 0.27 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001758.1 |  | 0.27 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001135.1 |  | 0.26 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001833.1 |  | 0.26 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001479.1 |  | 0.24 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001844.1 |  | 0.22 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000357.1 |  | 0.21 | NRP | cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val) | Penicillium rubens Wisconsin 54-1255
BGC0001825.1 |  | 0.21 | NRP | xenematide | Xenorhabdus nematophila AN6/1

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001128.1 |  | 0.60 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001641.1 |  | 0.60 | NRP | kolossin | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001132.1 |  | 0.60 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001758.1 |  | 0.60 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001135.1 |  | 0.60 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001833.1 |  | 0.59 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001479.1 |  | 0.57 | NRP | anabaenopeptin NZ857, nostamide A | Nostoc punctiforme PCC 73102
BGC0001844.1 |  | 0.55 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000357.1 |  | 0.54 | NRP | cyclo-(D-Phe-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Trp-D-Val-L-Val), cyclo-(D-Phe-L-Phe-D-Val-L-Ile), cyclo-(D-Phe-L-Phe-D-Ile-L-Val), cyclo-(D-Tyr-L-Trp-D-Val-L-Ile), cyclo-(D-Tyr-L-Trp-D-Ile-L-Val), cyclo-(D-Tyr-L-Phe-D-Val-L-Ile), cyclo-(D-Tyr-L-Phe-D-Ile-L-Val) | Penicillium rubens Wisconsin 54-1255
BGC0001825.1 |  | 0.54 | NRP | xenematide | Xenorhabdus nematophila AN6/1

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
c00059_NZ_JARF.. - Region 1 - terpene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 91,975 - 112,838 nt. (total: 20,864 nt) Show pHMM detection rules used
terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000294.1 |  | 0.15 | NRP | acinetobactin | Acinetobacter baumannii
BGC0000703.1 |  | 0.15 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000698.1 |  | 0.15 | Saccharide | hygromycin A | Streptomyces hygroscopicus
BGC0001890.1 |  | 0.07 | NRP | amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4 | Vibrio campbellii ATCC BAA-1116
BGC0000319.1 |  | 0.06 | NRP | cephamycin C | Streptomyces clavuligerus ATCC 27064
BGC0001653.1 |  | 0.06 | Polyketide | linfuranone B, linfuranone C | Microbispora sp. GMKU363
BGC0000001.1 |  | 0.04 | Polyketide | abyssomicin C, atrop-abyssomicin C | Verrucosispora maris AB-18-032
BGC0000133.1 |  | 0.04 | Polyketide | quartromicin A1 | Amycolatopsis orientalis
BGC0000354.1 |  | 0.03 | NRP | friulimicin A, friulimicin B, friulimicin C, friulimicin D | Actinoplanes friuliensis
BGC0000269.1 |  | 0.03 | Polyketide, Saccharide | SF2575 | Streptomyces sp. SF2575

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000294.1 |  | 0.46 | NRP | acinetobactin | Acinetobacter baumannii
BGC0000703.1 |  | 0.45 | Saccharide | kanamycin | Streptomyces kanamyceticus
BGC0000698.1 |  | 0.45 | Saccharide | hygromycin A | Streptomyces hygroscopicus
BGC0001890.1 |  | 0.28 | NRP | amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4 | Vibrio campbellii ATCC BAA-1116
BGC0000319.1 |  | 0.25 | NRP | cephamycin C | Streptomyces clavuligerus ATCC 27064
BGC0001653.1 |  | 0.25 | Polyketide | linfuranone B, linfuranone C | Microbispora sp. GMKU363
BGC0000001.1 |  | 0.19 | Polyketide | abyssomicin C, atrop-abyssomicin C | Verrucosispora maris AB-18-032
BGC0000133.1 |  | 0.19 | Polyketide | quartromicin A1 | Amycolatopsis orientalis
BGC0000354.1 |  | 0.16 | NRP | friulimicin A, friulimicin B, friulimicin C, friulimicin D | Actinoplanes friuliensis
BGC0000269.1 |  | 0.16 | Polyketide, Saccharide | SF2575 | Streptomyces sp. SF2575

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
c00060_NZ_JARF.. - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 252,570 - 325,269 nt. (total: 72,700 nt) Show pHMM detection rules used
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
NRPS/PKS domains
MIBiG comparison
KnownClusterBlast
NRPS/PKS modules
Pfam domains
TIGRFAM domains
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A glossary is available here.
Selected features only
Show module domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000389.1 |  | 0.44 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0001833.1 |  | 0.37 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001128.1 |  | 0.36 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001131.1 |  | 0.36 | NRP | ambactin | Xenorhabdus miraniensis
BGC0001135.1 |  | 0.36 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001758.1 |  | 0.36 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001132.1 |  | 0.35 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001844.1 |  | 0.35 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000417.1 |  | 0.34 | NRP | rhodochelin | Rhodococcus jostii RHA1
BGC0001615.1 |  | 0.34 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000389.1 |  | 0.75 | NRP | massetolide A | Pseudomonas fluorescens SS101
BGC0001833.1 |  | 0.70 | NRP | icosalide A, icosalide B | Burkholderia gladioli
BGC0001128.1 |  | 0.69 | NRP | luminmide | Photorhabdus laumondii subsp. laumondii TTO1
BGC0001131.1 |  | 0.69 | NRP | ambactin | Xenorhabdus miraniensis
BGC0001135.1 |  | 0.69 | NRP | bicornutin A1, bicornutin A2 | Xenorhabdus budapestensis
BGC0001758.1 |  | 0.68 | NRP | rhizomide A, rhizomide B, rhizomide C | Paraburkholderia rhizoxinica HKI 454
BGC0001132.1 |  | 0.68 | NRP | xenotetrapeptide | Xenorhabdus nematophila ATCC 19061
BGC0001844.1 |  | 0.68 | NRP | holrhizin | Paraburkholderia rhizoxinica HKI 454
BGC0000417.1 |  | 0.67 | NRP | rhodochelin | Rhodococcus jostii RHA1
BGC0001615.1 |  | 0.67 | NRP | hexose-palythine-serine, hexose-shinorine | Heteroscytonema crispum UCFS10

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Module view
Shows module structures for each candidate in NRPS- and PKS regions. Genes are shown in predicted order, and are only present when containing at least one complete module. A domain glossary is available here.
Legend
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NRPS/PKS products
NRPS/PKS monomers
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 252569 - 325269:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (D-asp - X) + (phe - gly) + (D-X - D-glu - gly - X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS monomer predictions
Shows the predicted monomers for each adynelation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg60_236: X - glu - gly - X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (518..916): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DgegSGgVtK
    Nearest Stachelhaus code:
      glu
    Stachelhaus code match:
      50% (weak)
  AMP-binding (2031..2433): glu
  NRPSPredictor2: glu
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      glu, gln
    Single AA prediction:
      glu
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVWHFGRINK
    Nearest Stachelhaus code:
      glu
    Stachelhaus code match:
      100% (strong)
  AMP-binding (3540..3937): gly
  NRPSPredictor2: gly
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      gly, ala
    Single AA prediction:
      gly
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DILQLGLVWK
    Nearest Stachelhaus code:
      gly
    Stachelhaus code match:
      100% (strong)
  AMP-binding (4598..4994): X
  NRPSPredictor2: asp, asn, glu, gln, aad
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DgegSGgVtK
    Nearest Stachelhaus code:
      glu
    Stachelhaus code match:
      50% (weak)
ctg60_237: phe - gly
  Search NORINE for peptide: strict or relaxed
  AMP-binding (506..900): phe
  NRPSPredictor2: phe
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aromatic
    Large clusters prediction:
      phe, trp, phg, tyr, bht
    Small clusters prediction:
      phe, trp
    Single AA prediction:
      phe
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DAWTvAGVCK
    Nearest Stachelhaus code:
      phe
    Stachelhaus code match:
      90% (moderate)
  AMP-binding (1586..1983): gly
  NRPSPredictor2: gly
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      gly, ala, val, leu, ile, abu, iva
    Small clusters prediction:
      gly, ala
    Single AA prediction:
      gly
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DILQLGLVWK
    Nearest Stachelhaus code:
      gly
    Stachelhaus code match:
      100% (strong)
ctg60_238: pk - asp - X
  Search NORINE for peptide: strict or relaxed
  CAL_domain (35..472): pk
  minowa: NH2
  Prediction, score:
    NH2: 151.4
    AHBA: 7.1
    shikimic_acid: 0.0
    Acetyl-CoA: -1.6
    fatty_acid: -2.8
  AMP-binding (1129..1522): asp
  NRPSPredictor2: asp
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      asp, asn, glu, gln, aad
    Small clusters prediction:
      asp, asn
    Single AA prediction:
      asp
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLTKVGHVGK
    Nearest Stachelhaus code:
      asp
    Stachelhaus code match:
      100% (strong)
  AMP-binding (2644..3047): X
  NRPSPredictor2: hydrophilic
  SVM prediction details:
    Predicted physicochemical class:
      hydrophilic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DiefIGAIaK
    Nearest Stachelhaus code:
      leu
    Stachelhaus code match:
      60% (weak)
ctg60_248: X
  Search NORINE for peptide: strict or relaxed
  AMP-binding (43..444): X
  NRPSPredictor2: (unknown)
  SVM prediction details:
    NOTE: outside applicability domain
    Predicted physicochemical class:
      hydrophobic-aliphatic
    Large clusters prediction:
      N/A
    Small clusters prediction:
      N/A
    Single AA prediction:
      N/A
  Stachelhaus prediction details:
    Stachelhaus sequence:
      htNYraGfvK
    Nearest Stachelhaus code:
      orn
    Stachelhaus code match:
      40% (weak)