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Overview
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### Identified secondary metabolite regions using strictness 'relaxed'

NZ_AP014630.1

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 1 | RiPP-like | 1,193,461 | 1,204,324 |
Region 2 | siderophore | 1,760,845 | 1,774,104 | staphylobactin | Other | 12%
Region 3 | siderophore | 2,459,906 | 2,474,960 | acinetoferrin | NRP | 70%
Region 4 | arylpolyene | 3,746,533 | 3,787,765 | berninamycin A | RiPP | 13%

NZ_AP014630.1 - Region 1 - RiPP-like
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,193,461 - 1,204,324 nt. (total: 10,864 nt) Show pHMM detection rules used
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | RiPP-like | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001897.1 |  | 0.06 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000993.1 |  | 0.03 | NRP, Polyketide | FR901228 | Chromobacterium violaceum
BGC0002002.1 |  | 0.03 | NRP | 1,6-phenazinedimethanol, fontizine A | Serratia fonticola

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001897.1 |  | 0.25 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000993.1 |  | 0.16 | NRP, Polyketide | FR901228 | Chromobacterium violaceum
BGC0002002.1 |  | 0.15 | NRP | 1,6-phenazinedimethanol, fontizine A | Serratia fonticola

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_AP014630.1 - Region 2 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,760,845 - 1,774,104 nt. (total: 13,260 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001453.1 |  | 0.31 | Other | desferrioxamine | Streptomyces argillaceus
BGC0000940.1 |  | 0.30 | Other | desferrioxamin B, desferrioxamine E | Streptomyces coelicolor A3(2)
BGC0000295.1 |  | 0.29 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0000942.1 |  | 0.27 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0000939.1 |  | 0.27 | Other | aerobactin | Grimontia hollisae
BGC0000943.1 |  | 0.19 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000866.1 |  | 0.18 | Other | polyhydroxyalkanoate | Burkholderia sp. DSM 9242
BGC0000867.1 |  | 0.17 | Other | polyhydroxyalkanoic acids | Ectothiorhodospira shaposhnikovii
BGC0001120.1 |  | 0.16 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000896.1 |  | 0.14 | Other | cycloserine | Streptomyces lavendulae subsp. lavendulae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001453.1 |  | 0.64 | Other | desferrioxamine | Streptomyces argillaceus
BGC0000940.1 |  | 0.64 | Other | desferrioxamin B, desferrioxamine E | Streptomyces coelicolor A3(2)
BGC0000295.1 |  | 0.63 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0000942.1 |  | 0.61 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0000939.1 |  | 0.60 | Other | aerobactin | Grimontia hollisae
BGC0000943.1 |  | 0.51 | Other | staphylobactin | Staphylococcus aureus subsp. aureus NCTC 8325
BGC0000866.1 |  | 0.49 | Other | polyhydroxyalkanoate | Burkholderia sp. DSM 9242
BGC0000867.1 |  | 0.48 | Other | polyhydroxyalkanoic acids | Ectothiorhodospira shaposhnikovii
BGC0001120.1 |  | 0.46 | NRP, Polyketide | burkholderic acid | Burkholderia thailandensis E264
BGC0000896.1 |  | 0.44 | Other | cycloserine | Streptomyces lavendulae subsp. lavendulae

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_AP014630.1 - Region 3 - siderophore
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 2,459,906 - 2,474,960 nt. (total: 15,055 nt) Show pHMM detection rules used
siderophore: IucA_IucC

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | siderophore | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000295.1 |  | 0.40 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0001572.1 |  | 0.35 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001531.1 |  | 0.31 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0000940.1 |  | 0.31 | Other | desferrioxamin B, desferrioxamine E | Streptomyces coelicolor A3(2)
BGC0001453.1 |  | 0.30 | Other | desferrioxamine | Streptomyces argillaceus
BGC0001478.1 |  | 0.22 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000941.1 |  | 0.21 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000942.1 |  | 0.21 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001713.1 |  | 0.20 | Other | ochrobactin | Ochrobactrum anthropi
BGC0000939.1 |  | 0.20 | Other | aerobactin | Grimontia hollisae

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000295.1 |  | 0.72 | NRP | acinetoferrin | Acinetobacter haemolyticus
BGC0001572.1 |  | 0.68 | Other | desferrioxamine E | Pantoea agglomerans
BGC0001531.1 |  | 0.64 | Other | bisucaberin B | Tenacibaculum mesophilum
BGC0000940.1 |  | 0.64 | Other | desferrioxamin B, desferrioxamine E | Streptomyces coelicolor A3(2)
BGC0001453.1 |  | 0.64 | Other | desferrioxamine | Streptomyces argillaceus
BGC0001478.1 |  | 0.55 | Other | desferrioxamine E | Streptomyces sp. ID38640
BGC0000941.1 |  | 0.54 | Other | desferrioxamin B | Streptomyces griseus subsp. griseus NBRC 13350
BGC0000942.1 |  | 0.53 | Other | petrobactin | Bacillus anthracis str. Ames
BGC0001713.1 |  | 0.53 | Other | ochrobactin | Ochrobactrum anthropi
BGC0000939.1 |  | 0.52 | Other | aerobactin | Grimontia hollisae

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names
NZ_AP014630.1 - Region 4 - arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 3,746,533 - 3,787,765 nt. (total: 41,233 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
MIBiG comparison
KnownClusterBlast
Pfam domains
TIGRFAM domains
Similar gene clusters
Shows careas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000922.1 |  | 0.22 | Other | pseudomonas quinolone signal (PQS) | Pseudomonas aeruginosa PAO1
BGC0001897.1 |  | 0.17 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000896.1 |  | 0.17 | Other | cycloserine | Streptomyces lavendulae subsp. lavendulae
BGC0000016.1 |  | 0.15 | Other | amphotericin B | Streptomyces nodosus
BGC0001264.1 |  | 0.15 | Polyketide | betaenone A, betaenone B, betaenone C | Phoma betae
BGC0001280.1 |  | 0.15 | Polyketide | betaenone C, betaenone A | Phoma betae
BGC0001778.1 |  | 0.14 | Other | showdomycin | Streptomyces showdoensis
BGC0001987.1 |  | 0.14 | Polyketide | koreenceine A, koreenceine B, koreenceine C, koreenceine D | Pseudomonas koreensis
BGC0000255.1 |  | 0.14 | Polyketide | pederin | Uncultured bacterium
BGC0000228.1 |  | 0.14 | Polyketide | granaticin | Streptomyces violaceoruber

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000922.1 |  | 0.55 | Other | pseudomonas quinolone signal (PQS) | Pseudomonas aeruginosa PAO1
BGC0001897.1 |  | 0.48 | Polyketide | cepacin A | Burkholderia ambifaria IOP40-10
BGC0000896.1 |  | 0.48 | Other | cycloserine | Streptomyces lavendulae subsp. lavendulae
BGC0000016.1 |  | 0.46 | Other | amphotericin B | Streptomyces nodosus
BGC0001264.1 |  | 0.45 | Polyketide | betaenone A, betaenone B, betaenone C | Phoma betae
BGC0001280.1 |  | 0.45 | Polyketide | betaenone C, betaenone A | Phoma betae
BGC0001778.1 |  | 0.44 | Other | showdomycin | Streptomyces showdoensis
BGC0001987.1 |  | 0.44 | Polyketide | koreenceine A, koreenceine B, koreenceine C, koreenceine D | Pseudomonas koreensis
BGC0000255.1 |  | 0.43 | Polyketide | pederin | Uncultured bacterium
BGC0000228.1 |  | 0.43 | Polyketide | granaticin | Streptomyces violaceoruber

Similar known gene clusters
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.
Detailed Pfam domain annotation
Shows Pfam domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description. Domains with a bold border have Gene Ontology information.
Selected features only
Expand to show all names
Detailed TIGRFAM domain annotation
Shows TIGRFAM domains found in each gene within the region. Click on each domain for more information about the domain's accession, location, and description.
Selected features only
Expand to show all names