GCF_006770325.1_ASM677032v1_genomic - 7 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP021395.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	terpene	290,654	312,340
Region 2	betalactone	922,437	947,454
Region 3	RiPP-like	1,397,014	1,407,829
Region 4	T1PKS	2,362,816	2,410,384	capsular polysaccharide	Saccharide	20%
Region 5	ectoine	2,906,131	2,916,529	ectoine	Other	75%
Region 6	resorcinol	3,832,406	3,874,301
Region 7	phosphonate	4,371,322	4,412,194

NZ_CP021395.1 - Region 1 - terpene

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Location: 290,654 - 312,340 nt. (total: 21,687 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000647.1	0.33	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000656.1	0.24	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000634.1	0.21	Terpene	carotenoid	Brevundimonas sp. SD212
BGC0000643.1	0.21	Terpene	carotenoid	Brevundimonas vesicularis
BGC0000630.1	0.20	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000640.1	0.20	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000646.1	0.19	Terpene	β-carotein	uncultured bacterium
BGC0000633.1	0.18	Terpene	carotenoid	Streptomyces avermitilis
BGC0000664.1	0.17	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001227.1	0.16	Terpene	isorenieratene	Streptomyces collinus Tu 365

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000647.1	0.66	Terpene	carotenoid	Rhodobacter sphaeroides
BGC0000656.1	0.57	Terpene	zeaxanthin	Xanthobacter autotrophicus Py2
BGC0000634.1	0.53	Terpene	carotenoid	Brevundimonas sp. SD212
BGC0000643.1	0.53	Terpene	carotenoid	Brevundimonas vesicularis
BGC0000630.1	0.52	Terpene	(2R,3S,3'S)-2-hydroxyastaxanthin	Paracoccus haeundaensis
BGC0000640.1	0.52	Terpene	carotenoid	Enterobacteriaceae bacterium DC404
BGC0000646.1	0.51	Terpene	β-carotein	uncultured bacterium
BGC0000633.1	0.49	Terpene	carotenoid	Streptomyces avermitilis
BGC0000664.1	0.49	Terpene	isorenieratene	Streptomyces griseus subsp. griseus NBRC 13350
BGC0001227.1	0.47	Terpene	isorenieratene	Streptomyces collinus Tu 365

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP021395.1 - Region 2 - betalactone

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Location: 922,437 - 947,454 nt. (total: 25,018 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000312.1	0.16	NRP	bassianolide	Beauveria bassiana
BGC0000890.1	0.15	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas phenolica O-BC30
BGC0001783.1	0.15	Other	streptonigrin	Streptomyces flocculus
BGC0000706.1	0.15	Saccharide	kanamycin	Streptomyces kanamyceticus
BGC0000243.1	0.14	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0000260.1	0.14	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396
BGC0001983.1	0.14	Other	triacsins	Kitasatospora aureofaciens
BGC0000891.1	0.14	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas luteoviolacea 2ta16
BGC0001838.1	0.14	NRP	WLIP	Pseudomonas putida
BGC0001156.1	0.13	Terpene	platencin	Streptomyces platensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000312.1	0.47	NRP	bassianolide	Beauveria bassiana
BGC0000890.1	0.45	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas phenolica O-BC30
BGC0001783.1	0.45	Other	streptonigrin	Streptomyces flocculus
BGC0000706.1	0.45	Saccharide	kanamycin	Streptomyces kanamyceticus
BGC0000243.1	0.44	Polyketide	macrotetrolide	Streptomyces griseus subsp. griseus
BGC0000260.1	0.43	Polyketide	prodigiosin	Hahella chejuensis KCTC 2396
BGC0001983.1	0.43	Other	triacsins	Kitasatospora aureofaciens
BGC0000891.1	0.43	Other (Aminocoumarin)	pentabromopseudilin	Pseudoalteromonas luteoviolacea 2ta16
BGC0001838.1	0.43	NRP	WLIP	Pseudomonas putida
BGC0001156.1	0.42	Terpene	platencin	Streptomyces platensis

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP021395.1 - Region 3 - RiPP-like

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Location: 1,397,014 - 1,407,829 nt. (total: 10,816 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

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KnownClusterBlast

Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000903.1	0.21	Other	fluorometabolite	Streptomyces cattleya
BGC0001514.1	0.15	Other	aristeromycin	Streptomyces citricolor
BGC0001687.1	0.03	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSL12

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000903.1	0.54	Other	fluorometabolite	Streptomyces cattleya
BGC0001514.1	0.45	Other	aristeromycin	Streptomyces citricolor
BGC0001687.1	0.15	Other	N-tetradecanoyl tyrosine	uncultured bacterium CSL12

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP021395.1 - Region 4 - T1PKS

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Location: 2,362,816 - 2,410,384 nt. (total: 47,569 nt) Show pHMM detection rules used

T1PKS: cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS))

Legend:

core biosynthetic genes

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

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Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001909.1	0.31	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001340.1	0.30	Polyketide	byssochlamic acid	Byssochlamys fulva
BGC0001124.1	0.29	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0001749.1	0.28	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0001697.1	0.27	Polyketide	neurosporin A	Neurospora crassa OR74A
BGC0001504.1	0.27	Polyketide	amycomicin	Amycolatopsis sp. AA4
BGC0001913.1	0.27	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0001444.1	0.26	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001538.1	0.26	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001067.1	0.26	Polyketide, Terpene	fumagillin, β-trans-bergamotene, fumagillol	Aspergillus fumigatus Af293

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001909.1	0.65	Polyketide	strobilurin	Strobilurus tenacellus
BGC0001340.1	0.64	Polyketide	byssochlamic acid	Byssochlamys fulva
BGC0001124.1	0.62	Polyketide	pyranonigrin E	Aspergillus niger ATCC 1015
BGC0001749.1	0.62	Polyketide	epipyriculol	Pyricularia oryzae 70-15
BGC0001697.1	0.60	Polyketide	neurosporin A	Neurospora crassa OR74A
BGC0001504.1	0.60	Polyketide	amycomicin	Amycolatopsis sp. AA4
BGC0001913.1	0.60	Polyketide	phomoidride	fungal sp. ATCC 74256
BGC0001444.1	0.60	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001538.1	0.60	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0001067.1	0.60	Polyketide, Terpene	fumagillin, β-trans-bergamotene, fumagillol	Aspergillus fumigatus Af293

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Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 4, location 2362815 - 2410384:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (pk)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_2234

Search NORINE for peptide: strict or relaxed

AMP-binding (29..463): X

NRPSPredictor2: (unknown)

SVM prediction details:

NOTE: outside applicability domain

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: aLcplGGPvK
Nearest Stachelhaus code:: ala
Stachelhaus code match:: 50% (weak)

ctg1_2247

PKS_AT (532..822): pk

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 79.2%; Methylmalonyl-CoA: 66.7%; CE-Malonyl-CoA: 62.5%

minowa: Methylmalonyl-CoA

Prediction, score:

Methylmalonyl-CoA: 124.9
Malonyl-CoA: 111.7
Methoxymalonyl-CoA: 106.3
Ethylmalonyl-CoA: 88.0
Isobutyryl-CoA: 83.7
trans-1,2-CPDA: 60.4
2-Methylbutyryl-CoA: 59.8
Propionyl-CoA: 59.6
inactive: 36.7
Acetyl-CoA: 33.2
fatty_acid: 31.5
CHC-CoA: 31.0
3-Methylbutyryl-CoA: 26.4
Benzoyl-CoA: 25.6

NZ_CP021395.1 - Region 5 - ectoine

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Location: 2,906,131 - 2,916,529 nt. (total: 10,399 nt) Show pHMM detection rules used

ectoine: ectoine_synt

Legend:

core biosynthetic genes

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regulatory genes

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MIBiG comparison

KnownClusterBlast

Pfam domains

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000855.1	0.42	Other	ectoine	Methylomicrobium kenyense
BGC0000858.1	0.41	Other	ectoine	Methylobacter marinus
BGC0000853.1	0.41	Other	ectoine	Streptomyces anulatus
BGC0000852.1	0.39	Other	ectoine	Sporosarcina pasteurii
BGC0000857.1	0.36	Other	ectoine	Methylophaga alcalica
BGC0000859.1	0.33	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000856.1	0.33	Other	ectoine	Methylophaga thalassica
BGC0000854.1	0.26	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000860.1	0.23	Other	ectoine	Methylarcula marina
BGC0000919.1	0.14	Other	phaseolotoxin	Pseudomonas syringae

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000855.1	0.73	Other	ectoine	Methylomicrobium kenyense
BGC0000858.1	0.73	Other	ectoine	Methylobacter marinus
BGC0000853.1	0.72	Other	ectoine	Streptomyces anulatus
BGC0000852.1	0.71	Other	ectoine	Sporosarcina pasteurii
BGC0000857.1	0.68	Other	ectoine	Methylophaga alcalica
BGC0000859.1	0.67	Other	ectoine	Methylomicrobium alcaliphilum
BGC0000856.1	0.66	Other	ectoine	Methylophaga thalassica
BGC0000854.1	0.60	Other	ectoine	Methylomicrobium alcaliphilum 20Z
BGC0000860.1	0.56	Other	ectoine	Methylarcula marina
BGC0000919.1	0.43	Other	phaseolotoxin	Pseudomonas syringae

Similar known gene clusters

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP021395.1 - Region 6 - resorcinol

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Location: 3,832,406 - 3,874,301 nt. (total: 41,896 nt) Show pHMM detection rules used

resorcinol: DarB

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001184.1	0.26	Other	bacilysin	Bacillus velezensis FZB42
BGC0000888.1	0.26	Other	bacilysin	Bacillus sp. CS93
BGC0001444.1	0.24	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001538.1	0.24	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000855.1	0.23	Other	ectoine	Methylomicrobium kenyense
BGC0000857.1	0.23	Other	ectoine	Methylophaga alcalica
BGC0001476.1	0.22	Other (Nucleoside)	pseudouridimycin	Streptomyces sp.
BGC0001526.1	0.22	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0000219.1	0.21	Polyketide, Saccharide	elloramycin	Streptomyces olivaceus
BGC0000258.1	0.21	Polyketide	prodigiosin	Serratia sp.

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001184.1	0.60	Other	bacilysin	Bacillus velezensis FZB42
BGC0000888.1	0.60	Other	bacilysin	Bacillus sp. CS93
BGC0001444.1	0.58	Other	caboxamycin	Streptomyces sp. NTK 937
BGC0001538.1	0.58	NRP, Polyketide	caboxamycin	Streptomyces sp. NTK 937
BGC0000855.1	0.56	Other	ectoine	Methylomicrobium kenyense
BGC0000857.1	0.56	Other	ectoine	Methylophaga alcalica
BGC0001476.1	0.55	Other (Nucleoside)	pseudouridimycin	Streptomyces sp.
BGC0001526.1	0.55	Other	bartolosides E, bartolosides F, bartolosides G, bartolosides H, bartolosides I, bartolosides J, bartolosides K	Synechocystis salina LEGE 06099
BGC0000219.1	0.54	Polyketide, Saccharide	elloramycin	Streptomyces olivaceus
BGC0000258.1	0.54	Polyketide	prodigiosin	Serratia sp.

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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NZ_CP021395.1 - Region 7 - phosphonate

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Location: 4,371,322 - 4,412,194 nt. (total: 40,873 nt) Show pHMM detection rules used

phosphonate: phosphonates

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Gene details

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MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000897.1	0.26	Other	dehydrophos	Streptomyces luridus
BGC0001859.1	0.25	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000937.1	0.24	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0000843.1	0.23	Other (Non-NRP beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate	Streptomyces clavuligerus ATCC 27064
BGC0000904.1	0.23	Other	FR-900098	Streptomyces rubellomurinus
BGC0001739.1	0.23	Other	phosphonoacetic Acid	Streptomyces sp. NRRL F-525
BGC0002034.1	0.22	Other	perquinoline A, perquinoline B, perquinoline C	Streptomyces sp. IB2014 016-6
BGC0001441.1	0.21	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0002036.1	0.20	Other	dehydrofosmidomycin	Streptomyces lavendulae
BGC0001895.1	0.20	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000897.1	0.60	Other	dehydrophos	Streptomyces luridus
BGC0001859.1	0.58	Other (Phosphonate)	fosfomycin	Pseudomonas syringae
BGC0000937.1	0.57	Other	fosfazinomycin A	Streptomyces sp. WM6372
BGC0000843.1	0.57	Other (Non-NRP beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate	Streptomyces clavuligerus ATCC 27064
BGC0000904.1	0.57	Other	FR-900098	Streptomyces rubellomurinus
BGC0001739.1	0.56	Other	phosphonoacetic Acid	Streptomyces sp. NRRL F-525
BGC0002034.1	0.55	Other	perquinoline A, perquinoline B, perquinoline C	Streptomyces sp. IB2014 016-6
BGC0001441.1	0.54	Other	belactosin A, belactosin C	Streptomyces sp.
BGC0002036.1	0.53	Other	dehydrofosmidomycin	Streptomyces lavendulae
BGC0001895.1	0.52	Polyketide	huanglongmycin A, huanglongmycin B, huanglongmycin C	Streptomyces sp. CB09001

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

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Detailed TIGRFAM domain annotation

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