LOCUS       NZ_LN811363.1          11863 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_LN811363.1 Microvirga massiliensis strain JC119, whole genome
            shotgun sequence.
ACCESSION   NZ_LN811363
VERSION     NZ_LN811363.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:10:00
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 133123
            Orig. end    :: 144986
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11863
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[138123:139986](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6863
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..11863
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193)"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11863
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193)"
                     /tool="antismash"
     CDS             391..1125
                     /locus_tag="ctg14_151"
                     /transl_table=11
                     /translation="MAANCRSIAAWLGIGRFVISAGARYTAGTSCATATATAAATAAAA
                     TTAAATTAXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXTTATAAA
                     TATAAATAAAAATATAGNFPDAAYGCSAGRRRSALARGRHPHAHHLSRDVRASARHRAR
                     TVCARPTSCRRRRSVTRRDESR"
     CDS             1165..2073
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_152"
                     /sec_met_domain="TP_methylase (E-value: 4.4e-18, bitscore:
                     60.3, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAKTRRRRPADEQSRTTAKERLRCDIAIVGLGIAGLHQLTRQVE
                     ETIRRCTQVFVADTGTGMVEYLKSLGPDVVDLSTPDEARKHRVLSYRRMATEVVAAATA
                     HAPVCFATYGHPTMFCYPTTLIQRAAIVLDLKVEVLPGISFLDTLLCDLGVDPGFDGLQ
                     LYEATDLLVRRRPLQPDVACIITQAPMVANPYSHPGERKLESLRLLQDYLLAFYPPSHE
                     VVLATSAPHPLLEPLIQPIALGALAAALLPSTQLGTLFIPPTVHRPVADEALADRMRLV
                     PLTDRVPPRRPNRPPIGPEPP"
     PFAM_domain     1243..1677
                     /aSDomain="TP_methylase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00590.22"
                     /description="Tetrapyrrole (Corrin/Porphyrin) Methylases"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_152_0001"
                     /evalue="3.70E-16"
                     /label="ctg14_152"
                     /locus_tag="ctg14_152"
                     /protein_end="171"
                     /protein_start="26"
                     /score="59.8"
                     /tool="antismash"
                     /translation="IAIVGLGIAGLHQLTRQVEETIRRCTQVFVADTGTGMVEYLKSLG
                     PDVVDLSTPDEARKHRVLSYRRMATEVVAAATAHAPVCFATYGHPTMFCYPTTLIQRAA
                     IVLDLKVEVLPGISFLDTLLCDLGVDPGFDGLQLYEATDLL"
     CDS             2076..2852
                     /locus_tag="ctg14_153"
                     /transl_table=11
                     /translation="MERVTYVVASTPRSGSTLLCEGLEATGIVGRPAEVFAPAFTTMWK
                     RYWSLAPDCSFELYLQSALAYGTTANGVYGLKIHWEHVSELAKACFVTGEPSTVLNALF
                     PGTVFINIVRNDRRAQALSLFRAMETNEWCRFDGAPLPEADVGSLVFDHHRVSMLESAI
                     GAQQAGWERYFAVNRSIVLTIEYEQLDQNYRGEIARVVEFLGGDPTAASDIPEPRLKRQ
                     SDEVNRRWRMAMESAEILENSYEHSTIDHRGRRLLP"
     PFAM_domain     2088..2765
                     /aSDomain="Sulphotransf"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF09037.12"
                     /description="Stf0 sulphotransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_153_0002"
                     /evalue="7.40E-36"
                     /label="ctg14_153"
                     /locus_tag="ctg14_153"
                     /protein_end="230"
                     /protein_start="4"
                     /score="124.0"
                     /tool="antismash"
                     /translation="TYVVASTPRSGSTLLCEGLEATGIVGRPAEVFAPAFTTMWKRYWS
                     LAPDCSFELYLQSALAYGTTANGVYGLKIHWEHVSELAKACFVTGEPSTVLNALFPGTV
                     FINIVRNDRRAQALSLFRAMETNEWCRFDGAPLPEADVGSLVFDHHRVSMLESAIGAQQ
                     AGWERYFAVNRSIVLTIEYEQLDQNYRGEIARVVEFLGGDPTAASDIPEPRLKRQSDEV
                     NRRW"
     CDS             2806..3528
                     /locus_tag="ctg14_154"
                     /transl_table=11
                     /translation="MSTRRSIIVVDDFYLDPVAIRDYALRQSFYTPYEDEEQVRAGRVK
                     STWWATRFHQSDHCPVKRSPNLLRALEKATGETIDREHWNAPFPIDEWSKPILPPSGQV
                     SSCLWNCAFHVKPDNGQRLGDGVHNHVTDQWNGVGPNGWAGIIYLSPDAPVSGGLHMWR
                     SIDPKRQFDWMTPAENWQLIDSLGNIFNRLILVRGDIPHSGAGGWGSRLHEGRLYQTFF
                     FRTLDCSAEAVKLVGLDD"
     CDS             3521..4294
                     /locus_tag="ctg14_155"
                     /transl_table=11
                     /translation="MTDLASLLVDRPWLYRATPFPHVTSDQVFTADFYSELAEAILELL
                     SRGLSETPATGRFSRGMRGYDAYGIGITEELGHPLNVFLSPPWRDLLSDLFAVGRTPYV
                     FAGAHHHRPGGANGFIHTDFNPVWFPVSPPGRTSIRLPDPAVCDFKTGAGSLAPSEKIE
                     TIRGAVVIYYLLNEGWQPGDGGETGLFTGRNPESLTTRRPPLNNSLVAFECTPTSFHAF
                     LANRRPRTSIIMWVHRTFEEAVERYGEDQIERWQL"
     PFAM_domain     3998..4231
                     /aSDomain="2OG-FeII_Oxy_4"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13661.8"
                     /description="2OG-Fe(II) oxygenase superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_155_0003"
                     /evalue="8.70E-09"
                     /label="ctg14_155"
                     /locus_tag="ctg14_155"
                     /protein_end="237"
                     /protein_start="159"
                     /score="35.9"
                     /tool="antismash"
                     /translation="EKIETIRGAVVIYYLLNEGWQPGDGGETGLFTGRNPESLTTRRPP
                     LNNSLVAFECTPTSFHAFLANRRPRTSIIMWVH"
     CDS             4291..5004
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     87.6; E-value: 1.6e-26)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_156"
                     /transl_table=11
                     /translation="MKRVCLLTGASGLLGRSLIERCSSDYWFIAVHNNSPVDFATQDQF
                     FIDPLEPDRDIAMNDTAVFSIRANLASQDEVVRIVDEVVQTCGRVDLLVNAAARRDWSP
                     LLTPGAVDSADQLLAVNLLAPLRLTIEVAKRCWLSDPYGNIRNSRNVVNIASSAGLFVY
                     PDLGQALYATSKAALIHLTYHLASELWDLGVRVNGVAPNTFPGLVATDDVIDAVLDFDH
                     GNKTGQIAKLLGNRA"
     PFAM_domain     4456..4899
                     /aSDomain="adh_short"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00106.27"
                     /description="short chain dehydrogenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_156_0004"
                     /evalue="9.00E-22"
                     /label="ctg14_156"
                     /locus_tag="ctg14_156"
                     /protein_end="203"
                     /protein_start="55"
                     /score="77.6"
                     /tool="antismash"
                     /translation="IAMNDTAVFSIRANLASQDEVVRIVDEVVQTCGRVDLLVNAAARR
                     DWSPLLTPGAVDSADQLLAVNLLAPLRLTIEVAKRCWLSDPYGNIRNSRNVVNIASSAG
                     LFVYPDLGQALYATSKAALIHLTYHLASELWDLGVRVNGVAPNT"
     CDS             5001..6863
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR03975"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 175.8; E-value: 2.2e-53)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_157"
                     /sec_met_domain="TIGR03975 (E-value: 9e-200, bitscore:
                     659.2, seeds: 14, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 3.9e-14, bitscore: 47.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLLVNMPFAAVRPAIGPSLLKSHLAAIGYECCVLYLNLRMAQR
                     LGNSDFSYIADRTPTQSLSGDWVFAPGLFGSRPEADREYVAAFNERFGRYVDNAAPLAV
                     LQRARAMAEDFLEECLADDVWKLYDVIGFTSTFTQHVSSLALAQRLKQRYQDKLIVFGG
                     ANCEDQMGVAVHRLFPFVDYVCSGEADISFPRLIRALDSGENPSDIPGVIYRRDAQTRW
                     TSLVPQRVRDLDTLPMPDYDDYFEQLEMFGLSGSGILMESSRGCWWGEKHHCTFCGLNG
                     TAMAFRCKSASRVLAELDAQVARYRPAHVEMVDNILDMHYFRDLLPELHRRHLNLGLFY
                     ETKANLTKVQVQELFAAGITSIQPGIESFSTSVLKIMRKGTTALQNVQLLKWCKEVGMK
                     VYWNLLYGFPGEDPNEYKIMSALIDKITHLDPPQGMGGIRLDRFSPNFVSAADLGLCNV
                     RPDRSYRYIYDLPESDLYGLAYYFEHDYRDQRDPHQYIHGTEQAMRRWYAESGGRGLVY
                     VDHGDHLAIWDFRTIAEERLTILTGSDRALYLFCDAQRSAPNIMKFAAEELGLSAEAAM
                     EAVTRLAQANLIVEVDARFLSLAVSAPALPDTERSHKLSNALAF"
     aSDomain        5007..6800
                     /aSDomain="TIGR03975"
                     /aSTool="tigrfam"
                     /description="rSAM_ocin_1: ribosomal peptide maturation
                     radical SAM protein 1"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg14_157_0001"
                     /evalue="4.40E-199"
                     /identifier="TIGR03975"
                     /label="ctg14_157"
                     /locus_tag="ctg14_157"
                     /protein_end="600"
                     /protein_start="2"
                     /score="660.8"
                     /tool="antismash"
                     /translation="VLLVNMPFAAVRPAIGPSLLKSHLAAIGYECCVLYLNLRMAQRLG
                     NSDFSYIADRTPTQSLSGDWVFAPGLFGSRPEADREYVAAFNERFGRYVDNAAPLAVLQ
                     RARAMAEDFLEECLADDVWKLYDVIGFTSTFTQHVSSLALAQRLKQRYQDKLIVFGGAN
                     CEDQMGVAVHRLFPFVDYVCSGEADISFPRLIRALDSGENPSDIPGVIYRRDAQTRWTS
                     LVPQRVRDLDTLPMPDYDDYFEQLEMFGLSGSGILMESSRGCWWGEKHHCTFCGLNGTA
                     MAFRCKSASRVLAELDAQVARYRPAHVEMVDNILDMHYFRDLLPELHRRHLNLGLFYET
                     KANLTKVQVQELFAAGITSIQPGIESFSTSVLKIMRKGTTALQNVQLLKWCKEVGMKVY
                     WNLLYGFPGEDPNEYKIMSALIDKITHLDPPQGMGGIRLDRFSPNFVSAADLGLCNVRP
                     DRSYRYIYDLPESDLYGLAYYFEHDYRDQRDPHQYIHGTEQAMRRWYAESGGRGLVYVD
                     HGDHLAIWDFRTIAEERLTILTGSDRALYLFCDAQRSAPNIMKFAAEELGLSAEAAMEA
                     VTRLAQANLIVEVDARFLSLAV"
     PFAM_domain     5781..6251
                     /aSDomain="Radical_SAM"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04055.23"
                     /description="Radical SAM superfamily"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_157_0005"
                     /evalue="3.90E-12"
                     /label="ctg14_157"
                     /locus_tag="ctg14_157"
                     /protein_end="417"
                     /protein_start="260"
                     /score="46.9"
                     /tool="antismash"
                     /translation="ESSRGCWWGEKHHCTFCGLNGTAMAFRCKSASRVLAELDAQVARY
                     RPAHVEMVDNILDMHYFRDLLPELHRRHLNLGLFYETKANLTKVQVQELFAAGITSIQP
                     GIESFSTSVLKIMRKGTTALQNVQLLKWCKEVGMKVYWNLLYGFPGEDPNEYK"
     CDS             7044..7184
                     /locus_tag="ctg14_158"
                     /transl_table=11
                     /translation="VPRKGFSSEQIIAQLRQIEVQLAQGKSIALACKEAGISEQSSGMS
                     A"
     CDS             7359..7529
                     /locus_tag="ctg14_159"
                     /transl_table=11
                     /translation="MRLVQNPSQVNRFPPEIIAHAVRLYSRLPLSLRLIEEMLLERGIV
                     MKVVNMTTPFR"
     CDS             complement(7712..8494)
                     /locus_tag="ctg14_160"
                     /transl_table=11
                     /translation="MRRKLLIMGLPGAGKTTLARQLSARLNAVHFNADEIRENINKDLG
                     FSDEDRVEQARRMGWLCDRVVKTGCFAIADFVCPTVEARAAFLKEGDAFIVWVDGIARS
                     RFEDTNRLFTPPERFDIRVTPDGSPKYWVEEIARQVRPVFDPRRPTALILGRYQPFHDG
                     HKALVVEGLRRVGQACIAVRDTVGIDDKNPFSFEDVRSRIEHALREFEGQFTIVSLPNI
                     TNVFYGRDVGYLVERIELSDGLQAISASEMRRLLQDRR"
     PFAM_domain     complement(8231..8482)
                     /aSDomain="APS_kinase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01583.22"
                     /description="Adenylylsulphate kinase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_160_0006"
                     /evalue="1.20E-15"
                     /label="ctg14_160"
                     /locus_tag="ctg14_160"
                     /protein_end="88"
                     /protein_start="4"
                     /score="57.8"
                     /tool="antismash"
                     /translation="LLIMGLPGAGKTTLARQLSARLNAVHFNADEIRENINKDLGFSDE
                     DRVEQARRMGWLCDRVVKTGCFAIADFVCPTVEARAAFL"
     CDS             complement(8595..10775)
                     /locus_tag="ctg14_161"
                     /transl_table=11
                     /translation="VRDWVLRFNAHGPAGLVDRKPPGPPAILSDAHRQQLAALIEAGPI
                     AAMHGVVRWRLIDLIQWLWEEHRIAIXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
                     XXXXXEAAAKRALISLLLHLPAPLAPTQVRAA"
     PFAM_domain     complement(10575..10775)
                     /aSDomain="HTH_32"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13565.8"
                     /description="Homeodomain-like domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg14_161_0007"
                     /evalue="3.30E-09"
                     /label="ctg14_161"
                     /locus_tag="ctg14_161"
                     /protein_end="67"
                     /protein_start="0"
                     /score="37.3"
                     /tool="antismash"
                     /translation="VRDWVLRFNAHGPAGLVDRKPPGPPAILSDAHRQQLAALIEAGPI
                     AAMHGVVRWRLIDLIQWLWEEH"
ORIGIN
        1 ggtattgcgg aagttgaagg tgcgcactca tggccaaagc aagagcccgg cagtaatcgc
       61 tgcgcgtcat tgcccgctcg gcgcgcacga tattgatcaa tgcgcggttc gcgtctggtg
      121 gccaccgcca gtgcgttgac atggccacac ctcggctaat ccttcgcatt gcagattgag
      181 aaataagtat tgacgggctc gaatttaaag tcaatcttaa tcatacatac catcggggat
      241 tgctatgagc gatctgcgtg ccgtactgca acgagcacag accgattacg atttctatct
      301 gtcgctcctc gccaatccaa cggagacgtt gcgcgagtac acgctgagcg acgctgaacg
      361 agaggcgctg accggcgagt catctgcgcg atggcggcta attgcaggtc aattgctgcc
      421 tggcttggaa tcgggcggtt cgttatctcc gcaggcgcca ggtataccgc cgggactagc
      481 tgcgccaccg ccaccgccac cgccgccgcc accgccgccg ccgccaccac cgccgccgcc
      541 accaccgcnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      841 nnnnnnnnnn nnnnnnccac caccgccacc gccgccgcca ccgccacggc cgccgccacc
      901 gccgccgccg ccgccaccgc caccgccggg aattttcccg acgccgcata cgggtgtagt
      961 gccgggcgta ggcgatccgc cctcgcccgg ggtcgtcatc cgcacgccca tcacctttct
     1021 cgggatgtcc gggcttcggc acgacatcgt gctcgaacag tttgtgcgcg acccacaagt
     1081 tgtcgccgcc gtcgaagcgt tacgcgccgc gacgaatcac gatgaacgcc gggctgccgt
     1141 cgaccggctt atggagaacc tcggatgact gctaagacgc gtcgccgtcg accggctgat
     1201 gaacaatctc ggacgaccgc caaggagcgt ctacggtgtg acatcgcaat cgtagggctt
     1261 ggaatcgccg gcctgcatca acttacccgt caggtcgagg agacgatccg tcgctgcaca
     1321 caggtcttcg tggccgatac tgggaccggc atggtggagt acctcaagtc gcttggtccc
     1381 gatgtggtcg acttaagtac gccggacgaa gcgcgaaaac atcgggtcct ttcctaccgt
     1441 cggatggcca ccgaggttgt cgccgcggcc accgctcatg cgccggtctg cttcgcgacc
     1501 tacggtcacc cgacgatgtt ctgctacccg acgacgctca ttcaacgagc ggctatcgtg
     1561 ctcgatctca aggtcgaagt gctaccaggc atatctttcc ttgataccct actatgcgat
     1621 ctcggcgtcg atcctggctt tgacggcttg caactgtatg aggcaactga tcttctggtc
     1681 cgacggcggc ccttgcaacc cgacgtggcc tgcataatca cgcaggcgcc gatggtcgcc
     1741 aacccatata gtcatccggg cgaacgcaag ctggagagcc tgcgtctctt gcaagactac
     1801 ctgctggctt tttatcctcc cagccacgaa gttgtactag ccacctctgc cccgcacccc
     1861 ctgctcgaac cgttgatcca accaatcgcc cttggcgcgc tagccgcggc gctgttaccg
     1921 tccacccagc tgggcaccct gttcattcct ccgaccgtcc accgcccagt ggccgacgag
     1981 gcgttggcgg atcgaatgcg cctcgttccg ttgacggatc gcgtcccacc ccgccggcct
     2041 aaccggcccc caataggccc ggagccgccc taacgatgga acgtgtcact tacgtcgttg
     2101 catctactcc gcgctcagga agcacgctgt tgtgtgaagg cctcgaggca accgggatcg
     2161 tcggtcggcc ggcagaggtc ttcgctccag ctttcactac catgtggaag cgctattggt
     2221 cgcttgcgcc ggactgttcc ttcgagcttt atctgcagag tgcgctcgct tacggaacaa
     2281 ccgcgaatgg ggtgtatggc ctgaagattc actgggaaca tgtatcggag ctggccaaag
     2341 cttgctttgt aactggcgaa ccgagcacgg tcctcaatgc cctgttcccc ggtactgtgt
     2401 tcatcaacat cgtccgcaac gaccggcgag ctcaagccct gtcgcttttc cgagcaatgg
     2461 agaccaacga atggtgccgg ttcgacggag ccccgctgcc tgaagccgac gtcggatcgc
     2521 tagtgtttga tcaccacaga gtgagcatgc tcgaatcggc tatcggagct cagcaggccg
     2581 gttgggaacg ttacttcgcg gtgaataggt ccatagttct gaccatcgag tacgaacagc
     2641 tcgaccaaaa ttatcgcggg gagatcgcgc gcgtggtgga gttcctcggc ggcgacccga
     2701 ctgctgcgag cgatattccc gagccgcgcc tgaagcgaca gtctgatgag gtgaaccgac
     2761 gctggcgaat ggcgatggag tcggccgaga tcctggagaa ctcatatgag cactcgacga
     2821 tcgatcatcg tggtagacga cttctacctt gaccctgttg caatacgtga ttacgccctg
     2881 cgccagtcat tctatacgcc ttacgaagat gaagagcagg ttcgcgccgg tcgcgtgaaa
     2941 tcgacatggt gggccactcg cttccaccaa agtgatcact gtcccgtaaa gaggtcacca
     3001 aacttgcttc gcgccctgga gaaagcgacc ggggaaacga tcgaccgtga acactggaat
     3061 gcgccctttc ctatcgacga atggtcgaaa ccaattctac ccccgtctgg ccaggtgagc
     3121 tcctgcctct ggaactgcgc gtttcacgtc aagccagaca acggtcagcg cctcggcgac
     3181 ggggtacata accacgtgac cgaccaatgg aacggggtag gtccgaatgg ctgggcaggt
     3241 atcatttacc taagcccgga cgcaccggtg agcggcggct tgcacatgtg gcgcagcatc
     3301 gatccaaaac gacagttcga ctggatgacc ccggctgaga actggcagtt gatcgactca
     3361 ttaggaaata tcttcaatcg ccttatactt gtgcgtggcg atatcccgca cagcggagct
     3421 ggtggttggg gtagccgcct gcatgagggc cgcctttacc aaaccttctt tttccgcaca
     3481 cttgactgct cagctgaggc ggtgaagttg gtggggttgg atgactgacc ttgcatccct
     3541 tttggttgac cggccatggc tataccgcgc cacgcccttt ccgcacgtaa ccagcgatca
     3601 ggtgttcacc gctgacttct acagcgaact ggccgaagcg atattggagc tactaagccg
     3661 cggcctgagc gaaactccag cgaccggacg cttttcgcgg gggatgcgcg gttacgacgc
     3721 gtacggaata ggaattacgg aggaacttgg tcacccgttg aatgtgttct tgtcgccgcc
     3781 ctggcgagac ctattgagtg atcttttcgc agtcggacgg acgccctatg tgtttgccgg
     3841 cgctcaccac caccgcccgg gtggcgctaa cggattcatt cacacagatt tcaatcccgt
     3901 ctggtttccg gtgtcgccac cgggtcgcac ttcgatccga cttccagatc cagctgtgtg
     3961 cgacttcaag acgggcgcgg ggtctctcgc accgtctgag aagatcgaaa ccattcgcgg
     4021 ggcggtcgtc atctactacc tcctgaacga aggctggcag cccggcgatg gtggtgaaac
     4081 cggattgttc acaggccgca accctgaatc tcttactacc cgccgtccgc cgctcaacaa
     4141 cagcttggtt gcgtttgagt gcactccaac ctcgttccac gcattcctgg caaatcgccg
     4201 tccacggaca tcgatcatca tgtgggtgca tcgcactttt gaggaagcag tggagcgtta
     4261 cggagaagac cagatcgaac ggtggcagct atgaagcggg tttgtctgct cacgggagcc
     4321 agtggtctgc tcggtcgtag cctaattgag cggtgctcct cggattattg gttcatcgcc
     4381 gttcataaca actcgccggt cgattttgct acacaggacc agttttttat tgatccgtta
     4441 gaacctgatc gtgatatcgc catgaatgac accgccgttt tttcgatccg cgccaacctg
     4501 gcaagccagg acgaagtggt tcggattgtg gatgaagtcg ttcaaacatg cggacgggtc
     4561 gacctgctgg tcaacgcggc agctcgccgt gactggtcac ccctgctgac gccgggagca
     4621 gttgacagcg ccgatcagct gctggccgtc aacctgcttg cgccgcttcg actgactatc
     4681 gaggtggcaa agcgatgctg gctgtccgat ccctatggca acatccggaa cagccgcaac
     4741 gtggtgaaca tcgccagcag tgctggattg ttcgtttacc ccgacctcgg tcaagcactc
     4801 tatgcaacat ccaaagcagc gctgattcat ctcacgtacc acttggccag tgagctatgg
     4861 gatttaggtg tgcgagtgaa cggcgtcgct ccgaacacct tcccgggact cgtcgcgaca
     4921 gacgacgtta tcgacgccgt actggatttc gaccatggca acaagaccgg tcagattgca
     4981 aagctacttg ggaatcgcgc atgaaggtac ttcttgtcaa tatgcctttc gctgcggtcc
     5041 ggcctgccat cgggccaagc ctacttaaat ctcacctggc tgcaatcggc tacgagtgct
     5101 gtgtgcttta tctgaacctg cgcatggccc agcgtctagg aaacagtgac ttcagctaca
     5161 ttgctgatcg gactccgacg cagagccttt ccggtgattg ggtattcgca ccggggcttt
     5221 ttggttcgcg tcccgaagct gaccgtgagt acgttgcagc gtttaacgag cgattcggac
     5281 gctatgtcga caacgcggcg ccattggcgg ttctccagcg ggccagggca atggctgaag
     5341 acttcctcga ggaatgcctt gccgacgatg tctggaaact ttacgatgtc atcggcttca
     5401 cttccacctt cacccagcat gtctcctcgc ttgccctggc ccagcggctc aaacagcgtt
     5461 accaagacaa gctgatcgtc ttcggcgggg ccaactgcga ggaccagatg ggggtggccg
     5521 tccaccggct ttttccgttt gtggactacg tgtgcagcgg tgaggctgat atcagctttc
     5581 cgcgccttat tcgggccctg gacagtggtg agaatcccag cgatatcccg ggtgtgattt
     5641 atcgccgtga tgcccagacg cgatggactt cgttagttcc ccaacgagtt cgcgatctcg
     5701 acactcttcc catgcccgac tacgacgatt acttcgagca gctagagatg tttgggctgt
     5761 ctggatcagg cattctgatg gagtcgtccc ggggctgctg gtggggcgag aagcaccact
     5821 gcacgttctg tgggctcaat ggtaccgcaa tggcatttcg ttgtaaatca gcaagtcgtg
     5881 tgctcgccga actcgatgct caggttgcgc gctatcggcc tgctcatgtc gaaatggtcg
     5941 acaacatcct cgacatgcac tatttccgcg atctgctgcc tgagttgcat cgccggcatc
     6001 ttaatctcgg tctgttctat gagaccaagg ctaacctgac caaggtgcag gttcaggaac
     6061 tcttcgccgc tggaattaca tcgattcagc cagggattga gagtttcagc acaagcgtcc
     6121 taaaaatcat gcgcaaaggc acgactgcac tgcagaatgt ccaactgtta aagtggtgca
     6181 aggaagttgg catgaaggtg tactggaatc ttctctacgg tttccccgga gaggatccga
     6241 acgagtataa gatcatgtcg gccctcattg ataagatcac ccatcttgat ccaccacagg
     6301 gaatgggcgg aatccggctc gaccggttta gtcccaactt cgtctcggcg gcggacctgg
     6361 ggctgtgcaa tgtgcgtccg gaccgcagct atagatacat ctatgacctt cccgagtccg
     6421 acctctatgg cctagcctac tactttgagc acgactaccg cgaccagcga gacccgcacc
     6481 agtacattca cgggactgaa caagctatgc ggcgctggta tgccgagtca ggtgggcggg
     6541 gtctagtata cgttgatcac ggggatcacc tcgcgatttg ggatttccgg acgattgccg
     6601 aagagcggct gaccatcctc accggcagcg accgtgcgct ctatctcttc tgcgacgcgc
     6661 agcggtcagc accgaacatc atgaagtttg ctgccgaaga gctaggcctg tcagccgaag
     6721 cggcaatgga agctgtaact cggttggccc aggcaaatct catagtcgag gtagacgccc
     6781 ggtttttgag cttggccgtt agtgccccag ccctaccgga tacggaacgc tcacataaac
     6841 tgtcaaacgc ccttgccttc tgaccgcctc accctccttg gcgttcagag ggcggcatcg
     6901 tcacattaat tcgggcatga cagcgagccg tgtaggtgga ctggtacgtc aaagcccatt
     6961 agctacaagc atcaccgtga ccggactggg tggaattgga ccaagttgat tgagagactt
     7021 gacctggaac gaaggatcca tccgtgccgc gaaaggggtt tagttcggag cagatcatcg
     7081 cgcagttgcg ccagatcgag gtgcaactcg cgcagggcaa aagcattgcg ctcgcctgca
     7141 aggaggccgg catctcggag cagagctcag ggatgagtgc ctgaagctgg agatcttctc
     7201 cagcctcaag gaagcgcagg tggtgatcgg cggctggcgg gatcacgaca gtcgcgtgcg
     7261 gccccattcc gctctgggct atcgaccgcc cgcctccatg actatgaagg ctatcgcaca
     7321 gcagctcccc agacccgcaa tcatacagta gcctctcaat gcgcctggtt caaaatccta
     7381 gtcaggtcaa ccgcttccca cccgagatca tcgcccatgc cgttcggctg tattccaggc
     7441 tcccgttgag cctacggctg atcgaggaga tgctgctcga gcgcggcatc gtcatgaagg
     7501 tagttaacat gacaacgccc tttcgttagc tcccggccct gtgctcccag ccattgccat
     7561 tgaggatggg gttcgagccg aataccccgt ctgaacattc cgattggcga ataccaagat
     7621 gccactgtta acatcagtgc gcacaggtct cattagcgct ggatgcacaa ctatgcttgt
     7681 gacttgaggc ttcagtcata actatggttt cttacctccg atcctgcagg aggcgacgca
     7741 tctcagacgc agaaatagcc tgtaacccgt cactcaattc aatcctttca acaaggtatc
     7801 cgacgtctcg cccatagaag acatttgtga tgttcggcag tgatacaatt gtgaactgac
     7861 cttcgaattc tctcaatgca tgctctattc tggatcgcac atcttcaaag gaaaaaggat
     7921 ttttgtcgtc aatgcctact gtatcgcgca ctgcgatgca ggcctgacct actcgccgca
     7981 aaccctccac gaccaacgcc ttgtgtccat cgtgaaacgg ctgataccgc ccaaggataa
     8041 gagccgtggg cctcctggga tcgaatacgg gcctgacttg tcgtgcaatt tcttccaccc
     8101 agtatttcgg cgagccgtct ggcgtcaccc ggatgtcaaa gcgctcagga ggcgtaaata
     8161 ggcgatttgt atcttcgaat cggcttctgg caattccgtc tacccaaaca ataaaggcgt
     8221 cgccttcttt gaggaaagct gctctggcct ccacggtcgg acagacgaaa tccgctatag
     8281 caaaacatcc tgtttttact accctgtcgc acaaccagcc cattcgacgt gcttgctcga
     8341 cacggtcctc atctgagaaa ccgagatcct tatttatgtt ttctctaatt tcatctgcat
     8401 tgaaatgtac cgcgttcagt cgcgcggaca gctgcctagc caatgtagtt ttgcccgctc
     8461 cgggcagccc catgattaga agctttcgac gcatatgcta accatactcc agggcggcgt
     8521 taattcaaac attctgtgcg aacttggaca gtgtcatctt caggcagcgg agaggatctc
     8581 aacacctgga tcactcaggc cgccctcact tgcgtcggag caagcggagc gggtaaatgt
     8641 agcaggaggg agatcaaagc tcgtttagca gcagcttctt nnnnnnnnnn nnnnnnnnnn
     8701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9841 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9901 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9961 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10081 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10141 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10381 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    10561 nngatcgcga tccggtgttc ctcccagagc cactggatga gatcgatcag acgccagcgc
    10621 accacgccgt gcatggccgc gatcggaccc gcctcgatca gcgcggcgag ctgctggcga
    10681 tgcgcatcgc tcaggatcgc gggcgggccg ggcggcttgc ggtccacgag ccccgccggt
    10741 ccgtgcgcgt tgaagcgcaa cacccaatcg cgcaccgtct gcagcccgac ccgccgatcg
    10801 gggctggttc gctgcgtgtg ccgccgtcgt agatcgccgc cagagccaag aggcggcggg
    10861 tctgcgggcc atcctggctc tggcgcgcta gagcgcgtag cgccgcccgt cgtaatccgt
    10921 ccgcaacgcc accggaaccg acatggcaaa cctcctcgtt tgtcatgttg aatcagatca
    10981 acaccgcctc cgaaacccaa cgagtcacac tttccaggac ttggtatcac accctccggg
    11041 acttggtatg agtcgctgtg gtttcgtagg agactgctag aggagcgaga tcccgagaaa
    11101 cagactgacg atatcaagtg gtgcgaagaa gctgtgtgtc gctgaccctg cgaaaagcaa
    11161 tccaatcgca atattgtcct catcgaagag tatgctccca gaatcaccga actgacacgg
    11221 acagtccgca atgatctgat taacaaacag cgtattgcgg cctgtgggcc cgattgccca
    11281 gtaatccact ttaacaagtg cttgctgggc tacaattcgg cctgtagtca ggccactgcc
    11341 ggcgccatgc tttctcaccg accttccaac tagcgggcta tggctatttc caatccctcg
    11401 gactagccca atcccgtgta cctcattcca gcgctgcggc gtcagcgcga cagcggctgc
    11461 tgcatccaca aagttgtgca acgtgggccc aaaccagagc ggtacaaagt tacggacatt
    11521 gcccttgtag tcgcgggggt aagctcctcc ctgagctaac gctggttgga tcacaggagc
    11581 gccgggtatg gcgcgattga agtcggccaa cacatgatta cagctcacga agaggccgaa
    11641 agacctttcc gctgagctgg tcttggccca gataccaagc gatcctgcaa atgaaagata
    11701 atagcctcca ctctctccca ttctcaggga tcgaattggc ccagccagag caaacgcggt
    11761 cgctctcggg accgaaggag ggtccactag cagaggaggg gatgcgggaa catccatttc
    11821 ctcgacgtcc gtctcaatgc ccccgttcaa ctggcgcggg ata
//
