GCF_000285595.1_ASM28559v1_genomic - 2 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_HE611064.1

Region	Type	From	To	Most similar known cluster		Similarity
Region 1.1	NRPS,betalactone	204,287	248,141	bacillibactin	NRP:NRP siderophore	100%
Region 1.2	terpene	277,624	298,391

No secondary metabolite regions were found in these records:: NZ_HE611065.1; NZ_HE611066.1; NZ_HE611067.1; NZ_HE611068.1; NZ_HE611069.1; NZ_HE611070.1; NZ_HE611071.1; NZ_HE611072.1; NZ_HE611073.1; NZ_HE611074.1; NZ_HE611075.1; NZ_HE611076.1; NZ_HE611077.1; NZ_HE611078.1; NZ_HE611079.1; NZ_CAEW01000050 (original name was: NZ_CAEW01000050.1); NZ_CAEW01000049 (original name was: NZ_CAEW01000049.1); NZ_CAEW01000048 (original name was: NZ_CAEW01000048.1); NZ_CAEW01000047 (original name was: NZ_CAEW01000047.1)

Compact view

NZ_HE611064.1 - Region 1 - NRPS,betalactone

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Location: 204,287 - 248,141 nt. (total: 43,855 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Pfam domains

TIGRFAM domains

Detailed domain annotation

Selected features only

Show module domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001050.1	0.69	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000457.1	0.64	NRP	vicibactin	Rhizobium etli CFN 42
BGC0000389.1	0.64	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000465.1	0.62	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0000426.1	0.62	NRP	sevadicin	Paenibacillus larvae
BGC0000901.1	0.54	Other	ferrichrome	Aspergillus niger
BGC0000351.1	0.53	NRP	exochelin	Mycolicibacterium smegmatis
BGC0001873.1	0.52	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0000321.1	0.52	NRP	chaetocin	Collariella virescens
BGC0001825.1	0.52	NRP	xenematide	Xenorhabdus nematophila AN6/1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001050.1	0.68	NRP, Polyketide	thalassospiramide A	Tistrella bauzanensis
BGC0000457.1	0.66	NRP	vicibactin	Rhizobium etli CFN 42
BGC0000389.1	0.65	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0000465.1	0.64	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0000426.1	0.64	NRP	sevadicin	Paenibacillus larvae
BGC0000901.1	0.61	Other	ferrichrome	Aspergillus niger
BGC0000351.1	0.60	NRP	exochelin	Mycolicibacterium smegmatis
BGC0001873.1	0.60	NRP	pyrrolizixenamide A	Xenorhabdus szentirmaii DSM 16338
BGC0000321.1	0.59	NRP	chaetocin	Collariella virescens
BGC0001825.1	0.59	NRP	xenematide	Xenorhabdus nematophila AN6/1

Similar known gene clusters

Module view

Legend

Detailed Pfam domain annotation

Selected features only

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Detailed TIGRFAM domain annotation

Selected features only

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 204286 - 248141:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly) + (thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

ctg1_249

Search NORINE for peptide: strict or relaxed

AMP-binding (149..545): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

ctg1_250

Search NORINE for peptide: strict or relaxed

AMP-binding (435..818): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

ctg1_252

Search NORINE for peptide: strict or relaxed

AMP-binding (34..435): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PMPAlGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 90% (moderate)

NZ_HE611064.1 - Region 2 - terpene

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Location: 277,624 - 298,391 nt. (total: 20,768 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

MIBiG comparison

KnownClusterBlast

Pfam domains

TIGRFAM domains

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000851.1	0.10	Other	albonoursin	Streptomyces noursei ATCC 11455
BGC0001735.1	0.07	Other	pentostatine, vidarabine	Streptomyces antibioticus
BGC0000885.1	0.06	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0001215.1	0.04	NRP	conglobatin	Streptomyces conglobatus
BGC0000727.1	0.04	Saccharide	indigoidine	Streptomyces aureofaciens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000851.1	0.37	Other	albonoursin	Streptomyces noursei ATCC 11455
BGC0001735.1	0.27	Other	pentostatine, vidarabine	Streptomyces antibioticus
BGC0000885.1	0.24	Other	4-hydroxy-3-nitrosobenzamide	Streptomyces murayamaensis
BGC0001215.1	0.18	NRP	conglobatin	Streptomyces conglobatus
BGC0000727.1	0.17	Saccharide	indigoidine	Streptomyces aureofaciens

Similar known gene clusters

No matches found.

Detailed Pfam domain annotation

Selected features only

Expand to show all names

Detailed TIGRFAM domain annotation

Selected features only

Expand to show all names