LOCUS       NZ_HE610999.1          24095 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  NZ_HE610999.1 Kurthia massiliensis strain JC30, whole genome shotgun
            sequence.
ACCESSION   NZ_HE610999
VERSION     NZ_HE610999.1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.1.1
            Run date     :: 2024-03-14 15:19:24
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 259003
            Orig. end    :: 283098
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24095
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[269003:273098]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14095
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..24095
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..24095
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             1003..2058
                     /locus_tag="ctg4_284"
                     /transl_table=11
                     /translation="MSLLQQTIEQIQSTTKADHDEAVNYIDSLAKPPKSLGKLEKIAAQ
                     LAAINEGKFPETLKKAVIVCAGDHGVCDEGVTTNPQSVTVFQTLGFPKGTTGVCAIAKS
                     VGATVVPVDVGVMEDLPADAGVILKKVKYGTDNMRKGPAMTRDEAIRAIEVGIEVANEQ
                     VKNGVNLLATGEMGIGNTTPSAAILAVLEGVDPDEVTGFGAGVGEGGIAYKAQVIREAI
                     ALNQPNPDDAIDVLAKVGGLEIGAMAGVTLAAAANRVPIVIDGYISTVSACIAAALNPA
                     VRDYIIPSHASEEPGARIAAARLGVEPMLHMNMRLGEGSGAVLAFPIVDAALAMATEMV
                     TLEQAAALIEA"
     PFAM_domain     1039..2037
                     /aSDomain="DBI_PRT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02277.19"
                     /description="Phosphoribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_284_0001"
                     /evalue="2.80E-120"
                     /label="ctg4_284"
                     /locus_tag="ctg4_284"
                     /protein_end="345"
                     /protein_start="12"
                     /score="401.6"
                     /tool="antismash"
                     /translation="STTKADHDEAVNYIDSLAKPPKSLGKLEKIAAQLAAINEGKFPET
                     LKKAVIVCAGDHGVCDEGVTTNPQSVTVFQTLGFPKGTTGVCAIAKSVGATVVPVDVGV
                     MEDLPADAGVILKKVKYGTDNMRKGPAMTRDEAIRAIEVGIEVANEQVKNGVNLLATGE
                     MGIGNTTPSAAILAVLEGVDPDEVTGFGAGVGEGGIAYKAQVIREAIALNQPNPDDAID
                     VLAKVGGLEIGAMAGVTLAAAANRVPIVIDGYISTVSACIAAALNPAVRDYIIPSHASE
                     EPGARIAAARLGVEPMLHMNMRLGEGSGAVLAFPIVDAALAMATEMVTLEQA"
     aSDomain        1060..2040
                     /aSDomain="TIGR03160"
                     /aSTool="tigrfam"
                     /description="cobT_DBIPRT:
                     nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_284_0001"
                     /evalue="7.30E-122"
                     /identifier="TIGR03160"
                     /label="ctg4_284"
                     /locus_tag="ctg4_284"
                     /protein_end="346"
                     /protein_start="19"
                     /score="404.7"
                     /tool="antismash"
                     /translation="DEAVNYIDSLAKPPKSLGKLEKIAAQLAAINEGKFPETLKKAVIV
                     CAGDHGVCDEGVTTNPQSVTVFQTLGFPKGTTGVCAIAKSVGATVVPVDVGVMEDLPAD
                     AGVILKKVKYGTDNMRKGPAMTRDEAIRAIEVGIEVANEQVKNGVNLLATGEMGIGNTT
                     PSAAILAVLEGVDPDEVTGFGAGVGEGGIAYKAQVIREAIALNQPNPDDAIDVLAKVGG
                     LEIGAMAGVTLAAAANRVPIVIDGYISTVSACIAAALNPAVRDYIIPSHASEEPGARIA
                     AARLGVEPMLHMNMRLGEGSGAVLAFPIVDAALAMATEMVTLEQAA"
     CDS             complement(2207..2608)
                     /locus_tag="ctg4_285"
                     /transl_table=11
                     /translation="VRLWHTDIIPFLPKGQLLSQWRELNSIFAKEDKHVLINYIYDYPK
                     ADLRAYTDLIIQEMKARGYNIRSYEKMERYFADVEPTVVAHPFARDHDDTYLEICYFNL
                     KEKFIRGQKDYEAAQFEALDQYVKQQLNR"
     PFAM_domain     complement(2408..2605)
                     /aSDomain="Pyr_excise"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03013.16"
                     /description="Pyrimidine dimer DNA glycosylase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_285_0002"
                     /evalue="9.80E-13"
                     /label="ctg4_285"
                     /locus_tag="ctg4_285"
                     /protein_end="67"
                     /protein_start="1"
                     /score="48.3"
                     /tool="antismash"
                     /translation="RLWHTDIIPFLPKGQLLSQWRELNSIFAKEDKHVLINYIYDYPKA
                     DLRAYTDLIIQEMKARGYNIR"
     CDS             complement(2680..4335)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 205.3; E-value: 3.9e-62)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_286"
                     /transl_table=11
                     /translation="MKVQRRFAFQFLTQFITLCILLGILLFALVLIFGKIVSDEDLSSD
                     LLTIDDFSYDYHINAHYEIDDALKKAVRTQNVWLLVYDKNYHLKTAYNVPKDAPKAYDT
                     LLKDDTIFYNMESVTLGDSIQSYVIVGKKNESAITLDEMIQHINWQSATLPQIDSKQRI
                     YYVDKNGHVLDTRNVAKKDATVEALYYRHQYTVARYTDEATGKQLIVATKNIDDDILKV
                     LKRMLSPIIILGLISLCCFIVFIYFYTRKFANPLMLLMEWIRQIGQKNYDLPLNKKQQP
                     LFRTKKGRVRQRFKLYKDMIVTMEHMIDELKKHDAERHQMDKMREEWISGLSHDLKTPL
                     STIIGYTKMMRSTHEWTPKEQQQFLEVMDDKATYMKELIDDLTLTYRLKNARVPLQREQ
                     VEINEWLRRKLIHWMGTAEAEQYTFDFHTSHPTLYVQIDPVLFQRVIDNLLINAMKHNP
                     PGTIIAIETTVVAQQLQIIFKDNGIGMDEQTVAQLFNRYYRGTTTTEQSEGTGLGMAIT
                     EQLVKLHGGYIVAQSDINIGTTIIITLAMESTFS"
     PFAM_domain     complement(2695..3024)
                     /aSDomain="HATPase_c"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02518.28"
                     /description="Histidine kinase-, DNA gyrase B-, and
                     HSP90-like ATPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_286_0004"
                     /evalue="2.50E-20"
                     /label="ctg4_286"
                     /locus_tag="ctg4_286"
                     /protein_end="547"
                     /protein_start="437"
                     /score="73.1"
                     /tool="antismash"
                     /translation="DPVLFQRVIDNLLINAMKHNPPGTIIAIETTVVAQQLQIIFKDNG
                     IGMDEQTVAQLFNRYYRGTTTTEQSEGTGLGMAITEQLVKLHGGYIVAQSDINIGTTII
                     ITLAME"
     PFAM_domain     complement(3187..3366)
                     /aSDomain="HisKA"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00512.27"
                     /description="His Kinase A (phospho-acceptor) domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_286_0003"
                     /evalue="3.30E-12"
                     /label="ctg4_286"
                     /locus_tag="ctg4_286"
                     /protein_end="383"
                     /protein_start="323"
                     /score="46.4"
                     /tool="antismash"
                     /translation="MREEWISGLSHDLKTPLSTIIGYTKMMRSTHEWTPKEQQQFLEVM
                     DDKATYMKELIDDLT"
     CDS             complement(4332..5030)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 190.2; E-value: 6.3e-58)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_287"
                     /transl_table=11
                     /translation="MTQQKLLLVDDEMAILTMLETILHKEGFTHIDTATSAEMALTQCQ
                     NQTYDLILLDVMLPGQSGFDICPQLRQLTDAPIFFVTARSSDLDKLSGFALGGDDYITK
                     PFNPLEVVARIKAQLRRIQKVTPIQTTLTFPSLTIQMTSGEVYFKNKRIELPAQVYQLL
                     LFFCQHPNQLFTKAQLYEQVWQEAYLGEDNTVMVHIRKLRQKIEDDPSHPTRIITVRGL
                     GYKFVPGVSE"
     PFAM_domain     complement(4353..4580)
                     /aSDomain="Trans_reg_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00486.30"
                     /description="Transcriptional regulatory protein, C
                     terminal"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_287_0006"
                     /evalue="3.00E-25"
                     /label="ctg4_287"
                     /locus_tag="ctg4_287"
                     /protein_end="226"
                     /protein_start="150"
                     /score="88.2"
                     /tool="antismash"
                     /translation="KRIELPAQVYQLLLFFCQHPNQLFTKAQLYEQVWQEAYLGEDNTV
                     MVHIRKLRQKIEDDPSHPTRIITVRGLGYKF"
     PFAM_domain     complement(4686..5012)
                     /aSDomain="Response_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00072.26"
                     /description="Response regulator receiver domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_287_0005"
                     /evalue="1.60E-25"
                     /label="ctg4_287"
                     /locus_tag="ctg4_287"
                     /protein_end="115"
                     /protein_start="6"
                     /score="89.5"
                     /tool="antismash"
                     /translation="LLVDDEMAILTMLETILHKEGFTHIDTATSAEMALTQCQNQTYDL
                     ILLDVMLPGQSGFDICPQLRQLTDAPIFFVTARSSDLDKLSGFALGGDDYITKPFNPLE
                     VVARI"
     CDS             5168..5854
                     /locus_tag="ctg4_288"
                     /transl_table=11
                     /translation="MLAIAKQEFWQLTKNIKSIVMIALLLLASYYFARNGQTFAEIIGM
                     GAENDNALYATGLMMMVLFTGPLFVMALSHDIINREISSRTIRFLLTRTSADRIVWGKF
                     IGVCAFWLFCIVLAVAVIAITSHTFSPLIFATILCLLISEITIAFVVSIVITKPRMSMF
                     IGIVIGIAFPIVSYAVELTDKWWGKLRYVSPMHYIQNDNWEMIALPLVSVVIIFAAVQL
                     FKRGEY"
     PFAM_domain     5174..5701
                     /aSDomain="ABC2_membrane_2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF12679.9"
                     /description="ABC-2 family transporter protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_288_0007"
                     /evalue="4.10E-10"
                     /label="ctg4_288"
                     /locus_tag="ctg4_288"
                     /protein_end="178"
                     /protein_start="2"
                     /score="39.5"
                     /tool="antismash"
                     /translation="AIAKQEFWQLTKNIKSIVMIALLLLASYYFARNGQTFAEIIGMGA
                     ENDNALYATGLMMMVLFTGPLFVMALSHDIINREISSRTIRFLLTRTSADRIVWGKFIG
                     VCAFWLFCIVLAVAVIAITSHTFSPLIFATILCLLISEITIAFVVSIVITKPRMSMFIG
                     IVIGIAFPIVSYA"
     CDS             5854..6756
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 193.3; E-value:
                     8.3e-59)"
                     /gene_kind="transport"
                     /locus_tag="ctg4_289"
                     /transl_table=11
                     /translation="MLQVQQLTKNYGKKRVLKSIDLTVQQGEIFGFLGRNGAGKSTFIN
                     ILTGLAKQTSGTVTFFNGQTLTNDVNKKIGVLPDYSMFYPHLTALEHLRYFSAVSGEKV
                     SKAHAKDMLARVGLAKDVHTKVSKFSFGMKKKLGFAQAIIHDPQLIFLDEPTSGVDAES
                     AIVLQTLMRDLQHRGKTIFLTSHNLAEIEKLCDRIAILKDGVITKVGTIDELKTNDTDA
                     LYVQIKHGKVPEDCIVQLSKYTEIVKHTEQFTTLHIRDEKQNAEILKILHAHHVDVYRV
                     EMSEKTLEEIFIDEERKRA"
     PFAM_domain     5902..6324
                     /aSDomain="ABC_tran"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00005.29"
                     /description="ABC transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_289_0008"
                     /evalue="2.40E-28"
                     /label="ctg4_289"
                     /locus_tag="ctg4_289"
                     /protein_end="157"
                     /protein_start="16"
                     /score="99.4"
                     /tool="antismash"
                     /translation="LKSIDLTVQQGEIFGFLGRNGAGKSTFINILTGLAKQTSGTVTFF
                     NGQTLTNDVNKKIGVLPDYSMFYPHLTALEHLRYFSAVSGEKVSKAHAKDMLARVGLAK
                     DVHTKVSKFSFGMKKKLGFAQAIIHDPQLIFLDEPTS"
     PFAM_domain     6481..6735
                     /aSDomain="DUF4162"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13732.8"
                     /description="Domain of unknown function (DUF4162)"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_289_0009"
                     /evalue="6.80E-08"
                     /label="ctg4_289"
                     /locus_tag="ctg4_289"
                     /protein_end="294"
                     /protein_start="209"
                     /score="33.2"
                     /tool="antismash"
                     /translation="GTIDELKTNDTDALYVQIKHGKVPEDCIVQLSKYTEIVKHTEQFT
                     TLHIRDEKQNAEILKILHAHHVDVYRVEMSEKTLEEIFID"
     CDS             complement(6791..7840)
                     /locus_tag="ctg4_290"
                     /transl_table=11
                     /translation="LTLQTLGFSTFFEQQLQQTTWRPARITEQHKHMYRVCGEDFEWLA
                     TVSGSYAFHTHHAIDYPAIGDWVLVEQMPGEEKCAIHQLLTRKSVFTRKAAGREIEQQV
                     VAANIDIILLAMSLNEDFNVRRLERYVVAAWESGAVPMIVLTKADMCDDIPFYMQQLTD
                     VAMGIDCIVTSAITGEGIETLRQHVSTGKTAAIIGSSGAGKSSLTNALLGEETMKVADI
                     RADDAKGRHTTTHRALIQLPNGACFIDTPGMRELHIWTEQESLNTGFDDIETFAASCRF
                     RDCTHHQEPGCAVRQAIENGQLEAARLRNYVKLQKEVAFIERKTKAQEQLAAKRRLKKI
                     SKQLKAHYR"
     aSDomain        complement(6896..7651)
                     /aSDomain="TIGR00157"
                     /aSTool="tigrfam"
                     /description="TIGR00157: ribosome small subunit-dependent
                     GTPase A"
                     /detection="hmmscan"
                     /domain_id="TIGRFam_ctg4_290_0002"
                     /evalue="8.30E-52"
                     /identifier="TIGR00157"
                     /label="ctg4_290"
                     /locus_tag="ctg4_290"
                     /protein_end="315"
                     /protein_start="63"
                     /score="174.1"
                     /tool="antismash"
                     /translation="IGDWVLVEQMPGEEKCAIHQLLTRKSVFTRKAAGREIEQQVVAAN
                     IDIILLAMSLNEDFNVRRLERYVVAAWESGAVPMIVLTKADMCDDIPFYMQQLTDVAMG
                     IDCIVTSAITGEGIETLRQHVSTGKTAAIIGSSGAGKSSLTNALLGEETMKVADIRADD
                     AKGRHTTTHRALIQLPNGACFIDTPGMRELHIWTEQESLNTGFDDIETFAASCRFRDCT
                     HHQEPGCAVRQAIENGQLEAARLRNYVKLQ"
     PFAM_domain     complement(7064..7588)
                     /aSDomain="RsgA_GTPase"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03193.18"
                     /description="RsgA GTPase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_290_0010"
                     /evalue="7.90E-46"
                     /label="ctg4_290"
                     /locus_tag="ctg4_290"
                     /protein_end="259"
                     /protein_start="84"
                     /score="156.1"
                     /tool="antismash"
                     /translation="LTRKSVFTRKAAGREIEQQVVAANIDIILLAMSLNEDFNVRRLER
                     YVVAAWESGAVPMIVLTKADMCDDIPFYMQQLTDVAMGIDCIVTSAITGEGIETLRQHV
                     STGKTAAIIGSSGAGKSSLTNALLGEETMKVADIRADDAKGRHTTTHRALIQLPNGACF
                     IDTPGMRELHIW"
     CDS             8165..8782
                     /gene_functions="regulatory (smcogs) SMCOG1057:TetR family
                     transcriptional regulator (Score: 113.5; E-value: 2.7e-34)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_291"
                     /transl_table=11
                     /translation="MNKRSIKERIVEAALDLFQQEGYHGVSVEQIVAAAETSKGGFYHH
                     FKSKGDLLYEIHDVFISYILTETTREIAKYDSSLDQMNAMLSTCLHAFSIYQRHITVFY
                     EESVYLSQEHEAVIESKRNLYQQNLENILKSGQAQGVFRQELSVKMTALLISGTINWTY
                     RWFKVDGKLTMKEITKYFNDVLLRGVMTEFGYQEAIQKQYLL"
     PFAM_domain     8192..8329
                     /aSDomain="TetR_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00440.25"
                     /description="Bacterial regulatory proteins, tetR family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_291_0011"
                     /evalue="1.70E-17"
                     /label="ctg4_291"
                     /locus_tag="ctg4_291"
                     /protein_end="55"
                     /protein_start="9"
                     /score="63.0"
                     /tool="antismash"
                     /translation="IVEAALDLFQQEGYHGVSVEQIVAAAETSKGGFYHHFKSKGDLLY
                     E"
     PFAM_domain     8390..8731
                     /aSDomain="TetR_C_24"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF17932.3"
                     /description="Tetracyclin repressor-like, C-terminal
                     domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_291_0012"
                     /evalue="2.00E-27"
                     /label="ctg4_291"
                     /locus_tag="ctg4_291"
                     /protein_end="189"
                     /protein_start="75"
                     /score="95.8"
                     /tool="antismash"
                     /translation="DSSLDQMNAMLSTCLHAFSIYQRHITVFYEESVYLSQEHEAVIES
                     KRNLYQQNLENILKSGQAQGVFRQELSVKMTALLISGTINWTYRWFKVDGKLTMKEITK
                     YFNDVLLRGV"
     CDS             8835..9977
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 444.3; E-value:
                     6.1e-135)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_292"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 5.6e-40, bitscore:
                     131.1, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.5e-28, bitscore:
                     91.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.3e-53, bitscore:
                     174.5, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFELTKEQQMIRNMVRDFAQAEIAPHARELDKTHSFRKESFERM
                     GELGLLGIPFPEEYGGAGGDTISYALAVEEIGRACGGTGLSYAAAVSLGATPFYNFGTE
                     EQKQEYLVPLAQGKTLGAFGLTEPNAGSDAGGTQTKAVLEGDEWVINGEKQWITNAEYS
                     RQIVVTAVTGKDERGKNIITAIIVPTDTPGVKIRSDYDKMGVRASNTCEIILDNVRVPK
                     ENVLGDEKKGFGQFLNTLDGGRISIAALSVGIAQSAFDKALKYAQERQQFGKPISKLQA
                     IQFKLADMAMEIELARNMVHKAAWLKDNGKPFKLEAAYAKLFASEMGFRTCNQAIQIHG
                     GYGYMEEYDVERHLRDIKLMEIGEGTSEIQRVVISRNLGC"
     PFAM_domain     8850..9188
                     /aSDomain="Acyl-CoA_dh_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02771.18"
                     /description="Acyl-CoA dehydrogenase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_292_0013"
                     /evalue="5.20E-39"
                     /label="ctg4_292"
                     /locus_tag="ctg4_292"
                     /protein_end="118"
                     /protein_start="5"
                     /score="133.5"
                     /tool="antismash"
                     /translation="TKEQQMIRNMVRDFAQAEIAPHARELDKTHSFRKESFERMGELGL
                     LGIPFPEEYGGAGGDTISYALAVEEIGRACGGTGLSYAAAVSLGATPFYNFGTEEQKQE
                     YLVPLAQGK"
     PFAM_domain     9198..9488
                     /aSDomain="Acyl-CoA_dh_M"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02770.21"
                     /description="Acyl-CoA dehydrogenase, middle domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_292_0014"
                     /evalue="3.60E-27"
                     /label="ctg4_292"
                     /locus_tag="ctg4_292"
                     /protein_end="218"
                     /protein_start="121"
                     /score="94.5"
                     /tool="antismash"
                     /translation="AFGLTEPNAGSDAGGTQTKAVLEGDEWVINGEKQWITNAEYSRQI
                     VVTAVTGKDERGKNIITAIIVPTDTPGVKIRSDYDKMGVRASNTCEIILDNV"
     PFAM_domain     9525..9968
                     /aSDomain="Acyl-CoA_dh_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00441.26"
                     /description="Acyl-CoA dehydrogenase, C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_292_0015"
                     /evalue="1.70E-51"
                     /label="ctg4_292"
                     /locus_tag="ctg4_292"
                     /protein_end="378"
                     /protein_start="230"
                     /score="174.5"
                     /tool="antismash"
                     /translation="KGFGQFLNTLDGGRISIAALSVGIAQSAFDKALKYAQERQQFGKP
                     ISKLQAIQFKLADMAMEIELARNMVHKAAWLKDNGKPFKLEAAYAKLFASEMGFRTCNQ
                     AIQIHGGYGYMEEYDVERHLRDIKLMEIGEGTSEIQRVVISRNL"
     CDS             10001..11629
                     /NRPS_PKS="Domain: AMP-binding (12-445). E-value: 2.3e-107.
                     Score: 350.9. Matches aSDomain:
                     nrpspksdomains_ctg4_293_AMP-binding.1"
                     /NRPS_PKS="type: NRPS-like protein"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     430.5; E-value: 1.2e-130)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_293"
                     /sec_met_domain="AMP-binding (E-value: 9.9e-112, bitscore:
                     368.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VAQLIAQTIGKFLEERVQQFPDNEALVYADRDLRWSYRDFNNHAN
                     EVAKALMAIGLEKGEHFAVWTTNVPEWPGLQFGSGKMGSALVTINTNYRAMELEYILQQ
                     SDARAIILIDQVKDHSFIDTLYEVCPELKDATPGQLKSETLPQLHTVVVIGEKDYPGTY
                     NYEQFLALAENVSDEALAERHSSLTPDDVINLQYTSGTTGFPKGVMLTHRNLTNNALNI
                     AECMKLTNKDRLCIPVPFFHCFGCVIGTLTIVSAGGTMVPIQDYNPEVVLQTVQKEKCT
                     ALHGVPTMFISELNLPNIQEFDLSSLRTGVMAGSTCPIEVMKDVIDVLGIKDITICYGQ
                     TESSPVLTQTRTEDNITRKVETVGRALPNTEVKVVAPGTNEELPRGVQGEIVARGYCVM
                     KGYYKNQDATAEAIDQDGWLHTGDLGTMDEDGYLKVTGRLKDMIIRGGENIYPREIEEF
                     LYSHPQILDVQVVGVPDPKYGEELAAWIIPKDSSLDEADIRAYCTGKISRHKIPRHILF
                     VEEYPMTASGKIQKFKLREAFIEEG"
     aSDomain        10037..11335
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_293_AMP-binding.1"
                     /evalue="2.30E-107"
                     /label="ctg4_293_AMP-binding.1"
                     /locus_tag="ctg4_293"
                     /protein_end="445"
                     /protein_start="12"
                     /score="350.9"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="LEERVQQFPDNEALVYADRDLRWSYRDFNNHANEVAKALMAIGLE
                     KGEHFAVWTTNVPEWPGLQFGSGKMGSALVTINTNYRAMELEYILQQSDARAIILIDQV
                     KDHSFIDTLYEVCPELKDATPGQLKSETLPQLHTVVVIGEKDYPGTYNYEQFLALAENV
                     SDEALAERHSSLTPDDVINLQYTSGTTGFPKGVMLTHRNLTNNALNIAECMKLTNKDRL
                     CIPVPFFHCFGCVIGTLTIVSAGGTMVPIQDYNPEVVLQTVQKEKCTALHGVPTMFISE
                     LNLPNIQEFDLSSLRTGVMAGSTCPIEVMKDVIDVLGIKDITICYGQTESSPVLTQTRT
                     EDNITRKVETVGRALPNTEVKVVAPGTNEELPRGVQGEIVARGYCVMKGYYKNQDATAE
                     AIDQDGWLHTGDLGTMDEDGYLKVTGRLKDMIIR"
     PFAM_domain     10037..11335
                     /aSDomain="AMP-binding"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00501.30"
                     /description="AMP-binding enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_293_0016"
                     /evalue="1.60E-110"
                     /label="ctg4_293"
                     /locus_tag="ctg4_293"
                     /protein_end="445"
                     /protein_start="12"
                     /score="369.7"
                     /tool="antismash"
                     /translation="LEERVQQFPDNEALVYADRDLRWSYRDFNNHANEVAKALMAIGLE
                     KGEHFAVWTTNVPEWPGLQFGSGKMGSALVTINTNYRAMELEYILQQSDARAIILIDQV
                     KDHSFIDTLYEVCPELKDATPGQLKSETLPQLHTVVVIGEKDYPGTYNYEQFLALAENV
                     SDEALAERHSSLTPDDVINLQYTSGTTGFPKGVMLTHRNLTNNALNIAECMKLTNKDRL
                     CIPVPFFHCFGCVIGTLTIVSAGGTMVPIQDYNPEVVLQTVQKEKCTALHGVPTMFISE
                     LNLPNIQEFDLSSLRTGVMAGSTCPIEVMKDVIDVLGIKDITICYGQTESSPVLTQTRT
                     EDNITRKVETVGRALPNTEVKVVAPGTNEELPRGVQGEIVARGYCVMKGYYKNQDATAE
                     AIDQDGWLHTGDLGTMDEDGYLKVTGRLKDMIIR"
     CDS_motif       10586..10636
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_293_0001"
                     /evalue="1.80E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg4_293"
                     /protein_end="212"
                     /protein_start="195"
                     /score="23.5"
                     /tool="antismash"
                     /translation="QYTSGTTGFPKGVMLTH"
     CDS_motif       11150..11236
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg4_293_0002"
                     /evalue="1.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg4_293"
                     /protein_end="412"
                     /protein_start="383"
                     /score="20.3"
                     /tool="antismash"
                     /translation="PRGVQGEIVARGYCVMKGYYKNQDATAEA"
     PFAM_domain     11360..11584
                     /aSDomain="AMP-binding_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13193.8"
                     /description="AMP-binding enzyme C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_293_0017"
                     /evalue="2.10E-17"
                     /label="ctg4_293"
                     /locus_tag="ctg4_293"
                     /protein_end="528"
                     /protein_start="453"
                     /score="63.9"
                     /tool="antismash"
                     /translation="EIEEFLYSHPQILDVQVVGVPDPKYGEELAAWIIPKDSSLDEADI
                     RAYCTGKISRHKIPRHILFVEEYPMTASGK"
     PFAM_domain     11631..11960
                     /aSDomain="Biotin_carb_N"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00289.24"
                     /description="Biotin carboxylase, N-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_294_0018"
                     /evalue="7.70E-45"
                     /label="ctg4_294"
                     /locus_tag="ctg4_294"
                     /protein_end="110"
                     /protein_start="0"
                     /score="152.1"
                     /tool="antismash"
                     /translation="MFQKILIANRGEIARRVIRTCDKLGIQTVAIYSTADADSLHVRDA
                     SESYAVGEAQVNQSYLNVDAIIDVAKRSGAEAIHPGYGLLSENADFARAVEAAGLTWIG
                     PKPEVI"
     CDS             11631..12977
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090:acetyl-CoA carboxylase biotin carboxylase (Score:
                     662; E-value: 1.9e-200)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_294"
                     /sec_met_domain="RimK (E-value: 3e-06, bitscore: 21.5,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 8.3e-08, bitscore:
                     26.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKILIANRGEIARRVIRTCDKLGIQTVAIYSTADADSLHVRDA
                     SESYAVGEAQVNQSYLNVDAIIDVAKRSGAEAIHPGYGLLSENADFARAVEAAGLTWIG
                     PKPEVIEEMGSKLAARQRMEDAGVPIIKGTNNAVADVDEAARIAGDIGYPVMLKASAGG
                     GGIGMQAVHDEEALRKAFDGNQQRAANFFGDGTMFVEQLIEAPHHVEVQVLADTHGNVI
                     PVFERECSVQRRNQKVVEEAPSPFISPETREQMLDAAVAAAQAINYTNAGTIEFLVDAS
                     QNFYFLEMNTRLQVEHPITEEISGLDLVEWQLKVASGETLTVKREDLTINGHAIEVRIY
                     AEDPVKFFPSPGTIQTFSIPEGEGIRHELSVEAGSVVTPFYDPMIAKLVTHGDTRDVAI
                     ERMTDALDQYEVTGIKTNIPLLRKIMAHPVFKSGVTTTKFIDEYKEELK"
     PFAM_domain     11976..12596
                     /aSDomain="CPSase_L_D2"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02786.19"
                     /description="Carbamoyl-phosphate synthase L chain, ATP
                     binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_294_0019"
                     /evalue="7.80E-75"
                     /label="ctg4_294"
                     /locus_tag="ctg4_294"
                     /protein_end="322"
                     /protein_start="115"
                     /score="251.1"
                     /tool="antismash"
                     /translation="KLAARQRMEDAGVPIIKGTNNAVADVDEAARIAGDIGYPVMLKAS
                     AGGGGIGMQAVHDEEALRKAFDGNQQRAANFFGDGTMFVEQLIEAPHHVEVQVLADTHG
                     NVIPVFERECSVQRRNQKVVEEAPSPFISPETREQMLDAAVAAAQAINYTNAGTIEFLV
                     DASQNFYFLEMNTRLQVEHPITEEISGLDLVEWQLKVASGETLT"
     PFAM_domain     12636..12956
                     /aSDomain="Biotin_carb_C"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02785.21"
                     /description="Biotin carboxylase C-terminal domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_294_0020"
                     /evalue="9.40E-38"
                     /label="ctg4_294"
                     /locus_tag="ctg4_294"
                     /protein_end="442"
                     /protein_start="335"
                     /score="128.7"
                     /tool="antismash"
                     /translation="EVRIYAEDPVKFFPSPGTIQTFSIPEGEGIRHELSVEAGSVVTPF
                     YDPMIAKLVTHGDTRDVAIERMTDALDQYEVTGIKTNIPLLRKIMAHPVFKSGVTTTKF
                     IDE"
     CDS             12974..13183
                     /locus_tag="ctg4_295"
                     /transl_table=11
                     /translation="MMIKSEMAGTVWKVLVKEGDTVEEGQEVVILESMKMEIPVEAEES
                     GTVKRVIVSEGDFIELDADLVEVE"
     PFAM_domain     12977..13174
                     /aSDomain="Biotin_lipoyl"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00364.24"
                     /description="Biotin-requiring enzyme"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_295_0021"
                     /evalue="3.80E-18"
                     /label="ctg4_295"
                     /locus_tag="ctg4_295"
                     /protein_end="67"
                     /protein_start="1"
                     /score="65.2"
                     /tool="antismash"
                     /translation="MIKSEMAGTVWKVLVKEGDTVEEGQEVVILESMKMEIPVEAEESG
                     TVKRVIVSEGDFIELDADLVE"
     CDS             13193..14095
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 245.5;
                     E-value: 1.9e-74)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_296"
                     /sec_met_domain="HMGL-like (E-value: 1.4e-52, bitscore:
                     173.4, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPNNVRLKEVGPRDGLQNEKALIDTADKVALVNQLSETGLDYIE
                     VTSFVHPKWIPQLADAVDVLTQIDRKPGVTYAALVPNMKGLARALEANVDEVSVFMSAS
                     EGHNRENINKSIAETFPVLREVVEAAKAAGKTVRGYVSTVIACPYDGYTKPEQVKYVAD
                     HLFEMGVDEISLGDTIGVAVPPQVETLLDELMKHYAPEKLAMHFHDTHGTALANIVASL
                     PYGITTFDSAIGGLGGCPYAKGASGNVATEDVLYLLHSMGIETGVNLDQMMKASQFMEQ
                     KINRQLTSKQMAIFRGEQS"
     PFAM_domain     13208..14026
                     /aSDomain="HMGL-like"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00682.21"
                     /description="HMGL-like"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_296_0022"
                     /evalue="3.70E-51"
                     /label="ctg4_296"
                     /locus_tag="ctg4_296"
                     /protein_end="278"
                     /protein_start="5"
                     /score="174.3"
                     /tool="antismash"
                     /translation="VRLKEVGPRDGLQNEKALIDTADKVALVNQLSETGLDYIEVTSFV
                     HPKWIPQLADAVDVLTQIDRKPGVTYAALVPNMKGLARALEANVDEVSVFMSASEGHNR
                     ENINKSIAETFPVLREVVEAAKAAGKTVRGYVSTVIACPYDGYTKPEQVKYVADHLFEM
                     GVDEISLGDTIGVAVPPQVETLLDELMKHYAPEKLAMHFHDTHGTALANIVASLPYGIT
                     TFDSAIGGLGGCPYAKGASGNVATEDVLYLLHSMGIETGVNLDQMMKASQF"
     CDS             14092..14868
                     /NRPS_PKS="Domain: ECH (5-250). E-value: 2.4e-70. Score:
                     228.4. Matches aSDomain: nrpspksdomains_ctg4_297_ECH.1"
                     /NRPS_PKS="type: other"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023:enoyl-CoA hydratase (Score: 258.4; E-value:
                     9.1e-79)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_297"
                     /transl_table=11
                     /translation="MTLVQLEIKDRLAIITLNRPEAANAMSRAMLQAYIEVLEQVAHDR
                     SIRVVLLTGAGEKVFCAGADLKERQQMDEVMTKKTIALIGEAITKTEQLPQPVIAMMNG
                     MALGGGLELALACDIRVAATTAKLGLTETSLGIIPGAGGTQRLPRLIGTGRAKELIYTA
                     RRITAEEAVQLGLVEHIYIQELLREETEKLALEIAENAPLALIQAKRAIQQGMQTDLKT
                     GIDIERLAYERLLQTEDRLEGLAAFKEKRAPQYEGK"
     aSDomain        14107..14841
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg4_297_ECH.1"
                     /evalue="2.40E-70"
                     /label="ctg4_297_ECH.1"
                     /locus_tag="ctg4_297"
                     /protein_end="250"
                     /protein_start="5"
                     /score="228.4"
                     /tool="antismash"
                     /translation="LEIKDRLAIITLNRPEAANAMSRAMLQAYIEVLEQVAHDRSIRVV
                     LLTGAGEKVFCAGADLKERQQMDEVMTKKTIALIGEAITKTEQLPQPVIAMMNGMALGG
                     GLELALACDIRVAATTAKLGLTETSLGIIPGAGGTQRLPRLIGTGRAKELIYTARRITA
                     EEAVQLGLVEHIYIQELLREETEKLALEIAENAPLALIQAKRAIQQGMQTDLKTGIDIE
                     RLAYERLLQTEDRLEGLAAFKEK"
     PFAM_domain     14113..14862
                     /aSDomain="ECH_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00378.22"
                     /description="Enoyl-CoA hydratase/isomerase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_297_0023"
                     /evalue="4.30E-69"
                     /label="ctg4_297"
                     /locus_tag="ctg4_297"
                     /protein_end="257"
                     /protein_start="7"
                     /score="232.7"
                     /tool="antismash"
                     /translation="IKDRLAIITLNRPEAANAMSRAMLQAYIEVLEQVAHDRSIRVVLL
                     TGAGEKVFCAGADLKERQQMDEVMTKKTIALIGEAITKTEQLPQPVIAMMNGMALGGGL
                     ELALACDIRVAATTAKLGLTETSLGIIPGAGGTQRLPRLIGTGRAKELIYTARRITAEE
                     AVQLGLVEHIYIQELLREETEKLALEIAENAPLALIQAKRAIQQGMQTDLKTGIDIERL
                     AYERLLQTEDRLEGLAAFKEKRAPQYEG"
     CDS             14881..16422
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 526.6; E-value: 1.2e-159)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_298"
                     /transl_table=11
                     /translation="MTENTYTEKSYRDYKEDIVAGGAPKYHEKNSAQGKLFVRDRLKRL
                     FDDEFLVEDGAFANVLAGDLPADGVVTGIGKIHGRTVCVMANDSTVKAGSWGKRTVEKI
                     LRIQETAEKLEVPLLYLVDSAGARITDQIEMFPGRRGAGRIFYNQVKLSGRIPQICLLF
                     GPSAAGGAYIPAFCDIVVMVEKNASMYLGSPRMAEKVIGEHVDLETMGGAKMHCSVSGC
                     GDVLAKTEEEAIDYARRYLTYFPQNFREKPALQAPEEPTPAEKTLAEIIPENQNAAFNM
                     HHLIERVIDHGSFCEIKKLFAKELITGLARINGQAVGIIANQPKAKGGVLFHDSADKAA
                     KFINLCDAFHIPLIFLSDVPGFMIGTQVERQGIIRHGAKMIFAMSEATVPKLSVIVRKA
                     YGAGLYAMAGPAFEPDACIALTTAQIAVMGPEAAINAVYANKIAALPESERPAFIAQKT
                     EEYREEIDVYRLASELVVDDVIEPNELRQALVERLEVYKTKKLTFTERKHGVNPV"
     PFAM_domain     14968..16410
                     /aSDomain="Carboxyl_trans"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01039.24"
                     /description="Carboxyl transferase domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_298_0024"
                     /evalue="1.10E-158"
                     /label="ctg4_298"
                     /locus_tag="ctg4_298"
                     /protein_end="510"
                     /protein_start="29"
                     /score="529.1"
                     /tool="antismash"
                     /translation="NSAQGKLFVRDRLKRLFDDEFLVEDGAFANVLAGDLPADGVVTGI
                     GKIHGRTVCVMANDSTVKAGSWGKRTVEKILRIQETAEKLEVPLLYLVDSAGARITDQI
                     EMFPGRRGAGRIFYNQVKLSGRIPQICLLFGPSAAGGAYIPAFCDIVVMVEKNASMYLG
                     SPRMAEKVIGEHVDLETMGGAKMHCSVSGCGDVLAKTEEEAIDYARRYLTYFPQNFREK
                     PALQAPEEPTPAEKTLAEIIPENQNAAFNMHHLIERVIDHGSFCEIKKLFAKELITGLA
                     RINGQAVGIIANQPKAKGGVLFHDSADKAAKFINLCDAFHIPLIFLSDVPGFMIGTQVE
                     RQGIIRHGAKMIFAMSEATVPKLSVIVRKAYGAGLYAMAGPAFEPDACIALTTAQIAVM
                     GPEAAINAVYANKIAALPESERPAFIAQKTEEYREEIDVYRLASELVVDDVIEPNELRQ
                     ALVERLEVYKTKKLTFTERKHGV"
     CDS             16487..17902
                     /locus_tag="ctg4_299"
                     /transl_table=11
                     /translation="MKKTLGAFTLIAALTIPTMAQAAQNPSSPTINKMLTDTAKKYNIP
                     PEVLKGVAMQESGWRQFDEKGTPLVAEDNGIGIMQVTTKQSNISDDSLKNDIAANIEEG
                     ALILNTMYNRSSTPKVTGDRQDIEDWFFAVIAYNGMVPSNSPVVQQTGALNEKSYGQKV
                     YGKIYRQDFSNTGQHRVTAENKDVQLMDILNIRPTNVTYYENPAKMVFQKSTFEPTSRV
                     TRSNYALKVKDRVLMTAKGVKLRTKPSTVNSAEVTKLAQYERVTITGPYVFDTQQPNNR
                     FVWYPVQTSSGQKGYIASAYMQHTYPMIETRNVTMYAGENVTSYVRAIDAEDGDVSKYV
                     TANFNSGTPGVYDVPVTVRDSSAKTTIETIHVTVKPAVVIAKPKVKALKALGGKKVKVT
                     IAPVKGAVRYDIQYATNKNMKNAKTVKTTATSKTLTKLTKKKRYYVRVRAYVTVNGKAK
                     AGAYGAVKTIVAK"
     PFAM_domain     16598..16903
                     /aSDomain="SLT"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01464.22"
                     /description="Transglycosylase SLT domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_299_0025"
                     /evalue="1.10E-08"
                     /label="ctg4_299"
                     /locus_tag="ctg4_299"
                     /protein_end="139"
                     /protein_start="37"
                     /score="34.8"
                     /tool="antismash"
                     /translation="TAKKYNIPPEVLKGVAMQESGWRQFDEKGTPLVAEDNGIGIMQVT
                     TKQSNISDDSLKNDIAANIEEGALILNTMYNRSSTPKVTGDRQDIEDWFFAVIAYNG"
     PFAM_domain     17204..17392
                     /aSDomain="SH3_3"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF08239.13"
                     /description="Bacterial SH3 domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_299_0026"
                     /evalue="1.20E-07"
                     /label="ctg4_299"
                     /locus_tag="ctg4_299"
                     /protein_end="302"
                     /protein_start="239"
                     /score="32.1"
                     /tool="antismash"
                     /translation="KGVKLRTKPSTVNSAEVTKLAQYERVTITGPYVFDTQQPNNRFVW
                     YPVQTSSGQKGYIASAYM"
     CDS             complement(18006..18512)
                     /locus_tag="ctg4_300"
                     /transl_table=11
                     /translation="MDIRILTKDDASNYLAIRHRAVKEEPESFLPTYEEERQKDVDTYE
                     EMLADALSKTYGVFDNHELVGVTTVVQNGHEKMKHIAQIVGVYLAPEHRGKGYSKAMFE
                     RIVNDARQNDELEQLRLSVVDTMVPAIKLYERMGFEILCPDPKVMKMPDGKYLNELQMI
                     CFLTS"
     PFAM_domain     complement(18096..18440)
                     /aSDomain="Acetyltransf_1"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00583.27"
                     /description="Acetyltransferase (GNAT) family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_300_0027"
                     /evalue="8.30E-15"
                     /label="ctg4_300"
                     /locus_tag="ctg4_300"
                     /protein_end="139"
                     /protein_start="24"
                     /score="55.2"
                     /tool="antismash"
                     /translation="EPESFLPTYEEERQKDVDTYEEMLADALSKTYGVFDNHELVGVTT
                     VVQNGHEKMKHIAQIVGVYLAPEHRGKGYSKAMFERIVNDARQNDELEQLRLSVVDTMV
                     PAIKLYERMGF"
     CDS             complement(18538..18822)
                     /locus_tag="ctg4_301"
                     /transl_table=11
                     /translation="MFWIAIVVIVAITAAASLAERMIKSREKTKKLEIEMMREQIKLEQ
                     LKYDNYKMETEKMRLELQRDIQQAPTKEQLLNVDLQKDAFSSPSKMGKE"
     CDS             18954..19790
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     191.7; E-value: 2.6e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_302"
                     /transl_table=11
                     /translation="MSVETKTLADGHKIPVIGFGTVFMKGEAAAEGVASAIQHGYRLID
                     TAIRYDNEGAVGEGIRRSNVPREELFVTSKLRAQYYDRKVGYEMIEESLFRMGLDYLDL
                     YLLHWPNPKQDKYVEAWQTLIEAQKEGLVRSIGVCNFMPEHLNRLEEETGVLPVVNQIE
                     LHPYFSQEEMRAYNESKQIVTESWSPLSRGRTVIYDETLQKIAAHKNKTIGQIILRWHY
                     QIGAVAIPKAASEKHQLENLAIFDFSLTDEEMALINALTQDNGRIDNQDPREYEEF"
     PFAM_domain     19005..19733
                     /aSDomain="Aldo_ket_red"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF00248.23"
                     /description="Aldo/keto reductase family"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_302_0028"
                     /evalue="1.80E-42"
                     /label="ctg4_302"
                     /locus_tag="ctg4_302"
                     /protein_end="260"
                     /protein_start="17"
                     /score="145.5"
                     /tool="antismash"
                     /translation="GFGTVFMKGEAAAEGVASAIQHGYRLIDTAIRYDNEGAVGEGIRR
                     SNVPREELFVTSKLRAQYYDRKVGYEMIEESLFRMGLDYLDLYLLHWPNPKQDKYVEAW
                     QTLIEAQKEGLVRSIGVCNFMPEHLNRLEEETGVLPVVNQIELHPYFSQEEMRAYNESK
                     QIVTESWSPLSRGRTVIYDETLQKIAAHKNKTIGQIILRWHYQIGAVAIPKAASEKHQL
                     ENLAIFDFSLTDEEMALINAL"
     CDS             complement(19835..20377)
                     /locus_tag="ctg4_303"
                     /transl_table=11
                     /translation="MIVLWQLFLGFFIANILGYGGGPSSIPLMYDQIVKHYKWLDNEAF
                     SNMLALGNALPGPIATKIAAFVGYDTYGMLGVVVALFATIAPTVFLVIILMKVLQKHRD
                     SPIIKGMTTLIQPILAVMMAVIMWQLSSESFEKIGILQFLLIGAAAYWALQVKKYHPAF
                     VIIGAFLYGGIVLPRFM"
     PFAM_domain     complement(19862..20365)
                     /aSDomain="Chromate_transp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02417.17"
                     /description="Chromate transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_303_0029"
                     /evalue="6.00E-35"
                     /label="ctg4_303"
                     /locus_tag="ctg4_303"
                     /protein_end="172"
                     /protein_start="4"
                     /score="120.8"
                     /tool="antismash"
                     /translation="WQLFLGFFIANILGYGGGPSSIPLMYDQIVKHYKWLDNEAFSNML
                     ALGNALPGPIATKIAAFVGYDTYGMLGVVVALFATIAPTVFLVIILMKVLQKHRDSPII
                     KGMTTLIQPILAVMMAVIMWQLSSESFEKIGILQFLLIGAAAYWALQVKKYHPAFVIIG
                     AFLYG"
     CDS             complement(20374..20940)
                     /locus_tag="ctg4_304"
                     /transl_table=11
                     /translation="MKTEMKQLALGMLRSGIFGFGGGPSVMPLFRHEAVKNYKWMSDDE
                     FSETLAIANALPGPIATKMAGYIGYRLGGVFGAIWGVLCHIVPSAIMMIALLSLVGWLS
                     GSKVVMGMIAAVVPVVVVMLLEMALQFTQKSIKGIGIVLSIIFIAIAFVLLQVLHIHSG
                     IAVLLFLLYGSVHFKIFRRQKGAAK"
     PFAM_domain     complement(20431..20922)
                     /aSDomain="Chromate_transp"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF02417.17"
                     /description="Chromate transporter"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_304_0030"
                     /evalue="2.00E-33"
                     /label="ctg4_304"
                     /locus_tag="ctg4_304"
                     /protein_end="170"
                     /protein_start="6"
                     /score="115.8"
                     /tool="antismash"
                     /translation="QLALGMLRSGIFGFGGGPSVMPLFRHEAVKNYKWMSDDEFSETLA
                     IANALPGPIATKMAGYIGYRLGGVFGAIWGVLCHIVPSAIMMIALLSLVGWLSGSKVVM
                     GMIAAVVPVVVVMLLEMALQFTQKSIKGIGIVLSIIFIAIAFVLLQVLHIHSGIAVLLF
                     L"
     CDS             complement(20951..21412)
                     /gene_functions="regulatory (smcogs) SMCOG1120:AsnC family
                     transcriptional regulator (Score: 129.7; E-value: 1.1e-39)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg4_305"
                     /transl_table=11
                     /translation="MKEKVLLDDIDTKIVALLNEDGRMSYTDLSKAVNLSRVAVQARVQ
                     HLMEQGVIERFSAVINPEKMGLQVSAFFNVEVAPKYLQQVADTLAEDPNVSSLYHMTGP
                     SKLHMHGLFKNNQDMELFLEQRLYPLPGIMSVDSQILIKRYKSRIGMKL"
     PFAM_domain     complement(20984..21193)
                     /aSDomain="AsnC_trans_reg"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF01037.23"
                     /description="Lrp/AsnC ligand binding domain"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_305_0032"
                     /evalue="3.20E-13"
                     /label="ctg4_305"
                     /locus_tag="ctg4_305"
                     /protein_end="143"
                     /protein_start="73"
                     /score="49.5"
                     /tool="antismash"
                     /translation="NVEVAPKYLQQVADTLAEDPNVSSLYHMTGPSKLHMHGLFKNNQD
                     MELFLEQRLYPLPGIMSVDSQILIK"
     PFAM_domain     complement(21251..21394)
                     /aSDomain="HTH_24"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF13412.8"
                     /description="Winged helix-turn-helix DNA-binding"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_305_0031"
                     /evalue="1.90E-12"
                     /label="ctg4_305"
                     /locus_tag="ctg4_305"
                     /protein_end="54"
                     /protein_start="6"
                     /score="46.6"
                     /tool="antismash"
                     /translation="LDDIDTKIVALLNEDGRMSYTDLSKAVNLSRVAVQARVQHLMEQG
                     VIE"
     CDS             complement(22373..23338)
                     /locus_tag="ctg4_306"
                     /transl_table=11
                     /translation="MTAIANLRLPVIGSPMFIISTPKLVIEQCKAGIVGSMPALNARPK
                     ELLDEWLAEITEELASYNAKNPDRPAAPFAINQIVHNTNDRLEHDMELCVKYKVPIIIS
                     SLGARPEIFDAAHSYGGLCLHDVINNRFAKKAIEKGADGLIAVAAGAGGHAGALSPFAL
                     VQEIREWFDGPLALSGSIATGQSILAAQAMGADYAYIGSPFIATEEANAVEGYKQMIVD
                     SNADDIVYSNLFTGVHGNYLKPSIENAGLDPNNLAESDPSKMSFANANAKAWKDIWGSG
                     QGIGAIKDVQPVREYVDQLFREYESAQQRLSSKTFEVIHK"
     PFAM_domain     complement(22436..23335)
                     /aSDomain="NMO"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF03060.17"
                     /description="Nitronate monooxygenase"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_306_0033"
                     /evalue="2.80E-19"
                     /label="ctg4_306"
                     /locus_tag="ctg4_306"
                     /protein_end="301"
                     /protein_start="1"
                     /score="69.8"
                     /tool="antismash"
                     /translation="TAIANLRLPVIGSPMFIISTPKLVIEQCKAGIVGSMPALNARPKE
                     LLDEWLAEITEELASYNAKNPDRPAAPFAINQIVHNTNDRLEHDMELCVKYKVPIIISS
                     LGARPEIFDAAHSYGGLCLHDVINNRFAKKAIEKGADGLIAVAAGAGGHAGALSPFALV
                     QEIREWFDGPLALSGSIATGQSILAAQAMGADYAYIGSPFIATEEANAVEGYKQMIVDS
                     NADDIVYSNLFTGVHGNYLKPSIENAGLDPNNLAESDPSKMSFANANAKAWKDIWGSGQ
                     GIGAIKDVQPVREYVDQLF"
     CDS             23647..23904
                     /locus_tag="ctg4_307"
                     /transl_table=11
                     /translation="MLSFIWYIIIGGILGWLGGLILGKDIPGGVIGNIIAGIIGAFIGG
                     SLLGHWGPKVSDFYIFPTLLGTIILILIVGFIMKALGKGK"
     PFAM_domain     23746..23880
                     /aSDomain="Transgly_assoc"
                     /aSTool="clusterhmmer"
                     /database="34.0"
                     /db_xref="PF04226.15"
                     /description="Transglycosylase associated protein"
                     /detection="hmmscan"
                     /domain_id="clusterhmmer_ctg4_307_0034"
                     /evalue="3.40E-10"
                     /label="ctg4_307"
                     /locus_tag="ctg4_307"
                     /protein_end="78"
                     /protein_start="33"
                     /score="40.1"
                     /tool="antismash"
                     /translation="IIAGIIGAFIGGSLLGHWGPKVSDFYIFPTLLGTIILILIVGFIM
                     "
     CDS             23957..24049
                     /locus_tag="ctg4_308"
                     /transl_table=11
                     /translation="MEESVTLGKLCPSVTDFFLAFLLFFYILGK"
ORIGIN
        1 ctggcgtcgc agatggaaat gtagataagg aagattatgc attcggacca ctccaatcgt
       61 ttgaccatgc aactattcgc aagggaacag ttatcaaaat gcatgaacat aaaaacgatg
      121 aaattattag ttatttagta gatgggcaat ttgtacacga agattcagct ggttcgtacg
      181 aaacgttagc acataatcgt tacatgctta tgagtgcggg ggatagtctt ttccaccaag
      241 aaagtacacc agacatggat gcggagatgt tgcaaatttt tattcgacct cgtgaagcag
      301 atttagcgcc aaatgtgcaa tttgcctcgt atgaatcatc tgatgatttt cgatacattg
      361 cagggccagc acatgcacca ttgatcgttc gccaacgtgt atggatgtat gatttacacg
      421 ctgcatcagg cacatacaat ttgccaacag ctgaagaagg actcgtacca tgtgtatacg
      481 tttttgacgg tgcgattaca attaatggag cgcgtttaga aaaacgagat ggtgccatag
      541 gggcggacat cgtgtcatta acggtagaag aaccgagcgt cgtcgtcgta tttctcgttg
      601 acctagacgc atccgtaacg aaggcagggc catttagtgg gcgcaatcgt ccgactgaaa
      661 aaattgtcag ccgtatgtgg aaagatgtaa aaaacgatat tgactgattt ttcttaatac
      721 ggtaaagtgt acgtaactac ataaagcatt aggtgctcta gcaatagaga gaatagggaa
      781 taaagtgcaa aactttagcg gtcccgccac tgtaacagcg aataagatgg aaagatgcca
      841 ctgattgatc gggaaggctt catcttatgt tgacctgaag ccaggagacc tgcctaacgc
      901 tgtacacgta cgtatagatg atggaaaagt ctgtagttta tttcgcgatg ccgaataaac
      961 tacaggcttt ttgttttgtg tagattcaaa ggaggatatg atatgtcatt attacaacaa
     1021 acaatcgagc aaatccaatc aacaacgaaa gcggatcacg atgaagcggt gaactatatc
     1081 gattcgctag caaaaccacc gaaaagttta gggaagctag aaaaaatcgc agcacaactc
     1141 gcagcgatta acgaaggtaa attcccagaa acgttgaaaa aggccgtaat cgtttgtgca
     1201 ggcgaccacg gtgtttgtga tgaaggtgtt acaacgaacc cacaatcagt gacggtattc
     1261 caaacgcttg gctttccgaa aggaacgaca ggtgtatgtg ctatcgcgaa atcagtcggt
     1321 gcaacagttg tgccagtcga tgtcggtgtc atggaagatt taccagcaga tgcgggcgtt
     1381 attttgaaaa aagtgaagta tggtacggac aatatgcgta aagggccagc gatgacacgc
     1441 gacgaagcaa ttcgtgcaat tgaagttggc attgaagtag cgaatgaaca agtgaaaaac
     1501 ggtgtgaacc tactagcaac aggggaaatg ggcatcggca acacgacgcc aagcgcggcg
     1561 attttagctg tgttagaagg cgtagatcca gacgaagtga caggttttgg tgcgggcgtt
     1621 ggtgaaggtg gtattgcgta taaagcgcaa gttattcgtg aggcaatcgc gttaaatcag
     1681 ccaaatccag atgatgcgat tgacgtactt gctaaagtgg gtggccttga aatcggcgcg
     1741 atggcgggcg taacgttagc agcggcggcc aatcgtgtac caattgtcat tgacggttat
     1801 atttcaacag tttcagcatg tatcgctgcg gcattaaacc ccgcagtgag agattatatt
     1861 attccatcac atgcttcaga agaacctggc gcgcgtattg cagcggcacg tttaggtgta
     1921 gaaccaatgt tgcatatgaa tatgcgttta ggcgaagggt caggtgcggt attagcattt
     1981 ccaatcgtag atgcggcgtt agcaatggct actgaaatgg taacattgga acaagcggca
     2041 gccttaatcg aagcataagt tatgaaaaaa gaggctggga cataagtgta aaaacaccat
     2101 ctcaaatgag cataaaaaca accggaatcg cgctgtggcg cggttccggt tgtttgttgc
     2161 gaacactaaa aaaggaaaat gaaatgtttt gtcccagcct ctttttttaa cggtttaatt
     2221 gttgtttaac atattgatcg agcgcttcaa attgcgccgc ttcgtaatct ttttgaccac
     2281 gaataaattt ttcttttaaa ttaaaataac aaatttctaa atacgtatcg tcgtggtcgc
     2341 gtgcaaacgg atgtgccacg acagtcggtt cgacatctgc aaaataacgt tccatttttt
     2401 catatgagcg aatattgtat ccacgtgctt tcatttcttg aataatcaag tctgtataag
     2461 cacgtaaatc agctttcgga tagtcataaa tatagttaat gagtacgtgt ttatcctctt
     2521 tcgcaaaaat gctgtttagc tcacgccatt gtgataatag ctggcctttc ggtaaaaatg
     2581 gaatgatgtc tgtatgccat aaacgcactt gtgtcaccta gctttcaata agatgacttt
     2641 attgtagcaa aaacgtgttc aaatttgttg ttggagtgct tatgaaaaag tactttccat
     2701 cgctagtgta atgataatgg tcgtcccaat gttaatatca ctttgcgcaa cgatatatcc
     2761 cccatgcaat tttacgagct gttcggtaat ggccatgccg agaccggtac cttcactttg
     2821 ctcagtcgtt gtcgttccac gataatagcg gttaaacaat tgagcgacgg tttgttcatc
     2881 cataccgatg ccgttatctt taaaaatgat ttgcagttgc tgtgcgacaa ctgttgtttc
     2941 aatcgcaatg attgtcccag gtggattatg tttcatcgcg ttaattaata aattgtcaat
     3001 tacgcgttga aaaagtacag gatcgatttg cacgtaaagt gttgggtgtg atgtatgaaa
     3061 atcaaacgta tactgttcag cttctgccgt gcccatccaa tgaatcagtt tgcgacgcaa
     3121 ccactcgttt atttcgactt gctctctttg taaaggaacg cgcgcatttt ttaagcggta
     3181 agttaatgtt aaatcatcga ttagctcttt catataagtt gctttatcgt ccatcacttc
     3241 taaaaattgc tgctgctctt tcggcgtcca ttcatgtgtt gaacgcatca ttttcgtata
     3301 gccgataatt gtagaaaggg gagtctttaa atcgtgggat aagccgctaa tccactcctc
     3361 gcgcatttta tccatttggt gacgttcggc atcgtgcttt ttcaattcat cgatcatatg
     3421 ctccatcgtc acaatcatat ctttatacaa tttaaaacgt tgacgcacac gccctttttt
     3481 cgtacggaac aatggttgct gttttttatt aagcgggagg tcatagtttt tctgaccgat
     3541 ttgtcgaatc cattccatga gtaacatcag tgggttggca aattttcgtg tgtaaaaata
     3601 aatgaaaacg ataaaacaac aaagagaaat cagccctaaa atgataatag gcgacaacat
     3661 ccgcttcaat acttttaaaa tgtcatcatc gatgtttttt gtcgctacga ttagttgctt
     3721 acccgttgct tcatctgtat aacgagctac tgtatattga tgacggtagt aaagtgcttc
     3781 aacggtcgca tctttttttg caacgtttcg tgtgtcgagc acgtgcccgt ttttatctac
     3841 gtaataaatc cgctgtttac tatcaatttg tggcagcgtt gcagattgcc aattgatgtg
     3901 ttgaatcatt tcatcgagtg taatggcgct ttcattcttt tttccaacaa ttacataaga
     3961 ttgaatactg tcgccaagtg taacagattc catattgtaa aaaatagtat cgtccttcaa
     4021 tagcgtatcg tatgctttcg gagcatcttt gggtacgtta taagctgttt ttaagtgata
     4081 atttttgtca tacacgagta gccaaacgtt ttgtgtgcgc acggcttttt ttaatgcatc
     4141 atcaatttcg tagtgggcat taatatgata gtcgtaagaa aaatcgtcaa ttgtgagtaa
     4201 atcacttgat aaatcttcgt ccgagacaat tttgccaaaa attaagacga gggcgaatag
     4261 taaaatacca agcaaaatac agagcgtaat aaattgagtt aaaaattgaa aggcgaatcg
     4321 gcgttgtact ttcattcgct tacgccaggg acgaatttat agccaagccc acgaactgta
     4381 atgatacgcg taggatgact cgggtcgtct tcaatttttt gacgtaattt gcgaatgtgt
     4441 accatgacgg tattgtcttc gcctaaataa gcttcttgcc atacttgttc atatagttgc
     4501 gctttcgtga acagttgatt tgggtgttga cagaaaaaga gcagcaattg atacacttgc
     4561 gcgggcaatt caatacgttt gtttttaaag taaacctcac cagaagtcat ttgaattgtt
     4621 aatgatggaa atgtcagcgt cgtttggatt ggcgtcactt tttgaatacg acgaagctgt
     4681 gctttaatac gcgctacgac ttctaaagga ttgaacggtt ttgtaatgta gtcatcgcca
     4741 ccgagcgcaa agcccgacaa tttgtctaag tcagaagagc gcgctgtgac gaagaaaata
     4801 ggcgcatctg tcagttgtcg caattgcgga caaatatcaa acccgctctg accgggtagc
     4861 atgacatcta ataaaattaa gtcatacgtt tggttttggc attgcgttaa tgccatttca
     4921 gcagaggtcg ctgtatcaat atgtgtaaag ccttctttat gtaaaatcgt ctcaagcatc
     4981 gttaaaatag ccatttcatc gtcgacgagc agtaattttt gttgtgtcat agtagtcacc
     5041 tcttccatat tgtagcacgg ttctttttag tcattcggaa aattaaggaa atgttaaggt
     5101 aatgtttcat ttcacataag attcattcgt tatactaaga ttatcaacta ttgaaggaga
     5161 gaatcgtatg ttagcaattg caaaacaaga attttggcaa ctgacgaaaa atattaaatc
     5221 aatcgtcatg atcgcactct tattattagc atcttattat ttcgcacgaa acggccaaac
     5281 atttgccgaa attattggga tgggcgctga aaatgataac gcgctatatg cgactggttt
     5341 aatgatgatg gttttattta caggtccgtt gttcgtcatg gcattatcac atgacattat
     5401 taatcgtgaa atatcttctc gcacgattcg ttttttatta acgcgtacgt ctgcagatcg
     5461 tatcgtatgg gggaaattta tcggcgtctg cgcattttgg ctattttgta tcgtcttagc
     5521 ggttgctgtt atcgccatta catcacacac atttagtcca cttatttttg cgactatttt
     5581 atgcttatta atcagtgaaa ttacgattgc ctttgtcgtt tccattgtga tcacgaagcc
     5641 aagaatgtct atgtttatcg gcattgtcat cggtattgcg ttcccaattg tttcatatgc
     5701 tgtagagtta acggataaat ggtgggggaa attacgctac gtaagcccga tgcattacat
     5761 acaaaatgac aactgggaaa tgattgcatt gccacttgtt tcagtcgtca ttattttcgc
     5821 agccgttcaa ctatttaaac gaggtgaata ctaatgctac aagtgcaaca actaacaaaa
     5881 aactatggca aaaagcgcgt gttgaagtcg attgatttaa cggttcaaca aggagaaata
     5941 ttcggttttc tcggtcgtaa tggcgctggt aaatcaacat ttattaatat tttgacaggg
     6001 ttagcaaagc aaacgtctgg aacggtcaca ttttttaacg gtcaaacgtt aacgaatgat
     6061 gtgaacaaga aaattggtgt cctgccggat tactctatgt tttatccgca tttaacagcg
     6121 ctcgaacatt tacgctattt ctcagcagta agtggtgaaa aagtgtctaa agcacatgca
     6181 aaagatatgt tggcgcgcgt tggtttagca aaagatgttc atacgaaagt gagcaaattt
     6241 tcttttggga tgaaaaagaa attaggattt gcgcaggcga ttatccacga tccacaactg
     6301 attttcttag atgagccgac atcaggtgtt gatgcagaat cagctatcgt attacaaacg
     6361 ttaatgcgtg acttacaaca tcgcggaaaa acgatttttt taacgtcaca taatttagcg
     6421 gaaattgaaa aattatgtga tcgtatcgct attttaaaag atggtgtcat tacgaaagta
     6481 ggtacgattg atgagctgaa aacgaatgat acagatgctt tatacgtgca aattaaacat
     6541 ggtaaagtac cagaagattg catcgttcaa ctttctaaat acactgaaat tgtgaaacat
     6601 acggagcaat ttacgacgtt acacattcgc gacgaaaaac aaaacgctga aatactaaaa
     6661 atattacatg cgcatcatgt cgacgtttat cgcgttgaaa tgtctgaaaa aacgttagaa
     6721 gaaatattta tcgatgaaga acgaaaaaga gcataataaa aagcttgcga tcattcgcaa
     6781 gctttttttg ttatcggtaa tgtgctttta attgcttcga tatttttttc aaacggcgtt
     6841 ttgcggccaa ttgttcttgt gctttcgttt tacgctcgat aaacgcgacc tctttttgta
     6901 atttaacata attacgaagt cgtgctgctt caagttgccc gttctctatc gcttggcgta
     6961 cggcacagcc tggttcttga tgatgtgtac aatcgcggaa acgacacgat gcagcgaacg
     7021 tttcaatatc gtcaaaacct gtatttaaac tttcttgttc cgtccaaatg tgtaactcgc
     7081 gcatacctgg cgtatcaata aagcatgcgc catttggcaa ttgaatcaac gcgcggtgtg
     7141 tcgtcgtatg gcgacctttt gcgtcatcgg ctcgaatgtc cgccactttc atcgtttctt
     7201 ctccgagtaa tgcgttcgtt aaagatgatt ttccggcgcc tgatgatccg ataattgctg
     7261 ctgttttacc agttgatacg tgctgacgca atgtttcgat gccttcacca gtgatagcac
     7321 ttgtgacgat acaatcaatg cccattgcaa cgtctgttag ttgttgcata taaaacggga
     7381 tatcgtcgca catatcagct ttcgtcagta cgatcattgg cacagcgccc gattcccaag
     7441 cggcaacgac gtatcgttct aagcgacgga cgttaaagtc ttcatttaaa ctcatcgcta
     7501 gtaaaatgat atcaatattt gcagcaacga cttgttgctc tatttcacga ccagctgctt
     7561 tacgtgtaaa aacagatttt cgcgtcagca attgatgaat ggcgcatttt tcctcgccgg
     7621 gcatttgttc tacaagcacc cagtctccaa ttgctggata gtcgatcgca tgatgtgtat
     7681 gaaaagcata gctaccgctg accgttgcga gccattcgaa atcttctcca catacgcggt
     7741 acatatgttt atgttgttcg gtaatacggg ctggtcgcca tgttgtttgt tgtaattgtt
     7801 gttcaaaaaa tgttgaaaat cctaatgttt gtaatgtcaa tgtcgttcac tccttatatt
     7861 tgcgtacaaa aaaacctatg cctgagccgc agctcgttca taggttcgca aaaaagagcg
     7921 cactactaca ttagtagaca ctgtgaagat gcttctctat gaacgcgcat agcggcttac
     7981 ggctaaaaac aatcgcatat acatttgtca tagtgaacac cttcttccgt tttgtaagtt
     8041 acgtttacta tacgtgatga aaaataaaaa gtcaaattcg aagaaaatac ttgcataaag
     8101 cagaaatatt ttgttaaata taggtaatcc atatcgtgag gcaggtgatg gagggggtgg
     8161 cgaaatgaat aaacgctcga ttaaagagcg aatagttgaa gcggcacttg atttatttca
     8221 acaagaaggt taccacggtg tgagcgtcga gcaaatcgtc gcagccgctg aaacgtctaa
     8281 aggcgggttt tatcaccatt ttaaatcaaa aggggacttg ttgtatgaaa tacatgatgt
     8341 gttcatttcg tatatattga cggaaacgac acgtgaaatt gcaaaatatg actcttcgct
     8401 tgatcaaatg aatgcgatgt tgagcacatg tttacacgcg tttagtattt atcagcgaca
     8461 tattactgta ttttacgaag aaagcgttta cctttcacag gagcatgaag cggttatcga
     8521 gtctaaacgt aatttgtacc aacaaaattt agaaaatatt ttaaagtcgg gccaggcgca
     8581 aggggtgttt cgacaagagc tgtcggtcaa aatgacagcg ttgttgatta gcggcacgat
     8641 taactggacg tacagatggt ttaaagtaga tggtaagctt acgatgaaag aaattacgaa
     8701 atatttcaat gatgtgttac tacgtggtgt catgacggaa tttgggtatc aagaggcaat
     8761 tcaaaaacaa tatttactgt agcattttgg cgcaatcaga ccgactagtc ggttctaaac
     8821 agggaggtag caatatgaat tttgaattaa cgaaagagca acaaatgatc cgcaacatgg
     8881 tgagagactt tgcacaagcg gaaattgcac cgcacgcaag agaactagac aaaacgcatt
     8941 catttagaaa agaaagcttt gaacgcatgg gtgagcttgg actattaggt atccccttcc
     9001 cagaagagta cggcggtgca ggtggcgaca cgatttctta cgctttagca gtagaagaaa
     9061 ttggacgtgc gtgcggcggg acaggtttat cgtacgcagc agccgttagc ttaggcgcaa
     9121 caccgttcta caacttcggt acagaagaac aaaaacaaga atacctcgtg ccacttgcac
     9181 aagggaaaac gcttggggca ttcggtttaa ctgagccaaa cgccgggtca gatgccggtg
     9241 gtacacagac gaaagccgta ttagagggcg atgaatgggt tattaacggc gaaaagcaat
     9301 ggattacgaa tgcggagtac tcgcgtcaaa tcgttgttac agcggtaaca ggtaaagatg
     9361 aacgcggtaa aaatattatt acagcgatta tcgttccgac agacacacca ggcgttaaaa
     9421 tccgttcgga ctatgacaag atgggtgttc gcgcttcgaa tacgtgtgaa attattttag
     9481 ataacgtacg tgtaccgaaa gaaaatgtgc ttggcgatga gaaaaaaggt ttcggccaat
     9541 ttttaaatac gttagatggt ggtcgtattt cgattgcggc attatcagtc ggtattgcac
     9601 agtcggcatt tgataaagcg ttgaaatatg cacaagagcg tcaacaattc gggaagccga
     9661 tttcaaaact acaagcgatt caatttaaat tagcagacat ggcgatggaa attgaattgg
     9721 cgcgtaatat ggtgcataaa gcagcatggt taaaagataa cggcaaacca tttaaattag
     9781 aagcagctta tgcgaaatta tttgcgtcag aaatgggctt tagaacatgt aaccaagcga
     9841 ttcaaattca cggtggttac ggttacatgg aagaatatga tgttgagcgt catttacgtg
     9901 atattaaatt aatggaaatc ggtgaaggta cgtcagaaat tcaacgtgtt gtcatttcaa
     9961 gaaacttagg ctgttaacaa cttaataagg aggcatgtgt gtggcacaac taatcgcaca
    10021 aactattggt aaatttttag aggagcgcgt acaacagttt ccggacaatg aagcgttagt
    10081 atatgcagat cgagatttaa gatggagcta tcgagatttt aacaaccatg cgaatgaagt
    10141 tgcgaaagcg ttaatggcaa ttggacttga aaagggcgaa catttcgctg tatggacgac
    10201 gaatgttcct gaatggcctg ggctacaatt tggctctggc aaaatgggtt cggcactcgt
    10261 cacgattaat acgaattatc gcgcgatgga actggagtat attttacagc agtctgatgc
    10321 acgtgcaatt attttaatcg accaagtaaa agaccattca tttattgata cgttatatga
    10381 agtgtgtcca gagttaaaag atgcgacacc aggacaatta aagagtgaaa cattaccgca
    10441 gctacatacg gtcgttgtca tcggagaaaa ggattatcct ggtacgtaca attacgaaca
    10501 atttttagca ttagccgaaa atgtaagtga tgaagcatta gcagaacgtc atagtagctt
    10561 aacgccagat gatgttatca atttacaata cacatctggt acgacaggct ttccaaaagg
    10621 cgtcatgtta acgcatcgga atttaacgaa caatgcgttg aatatcgctg aatgtatgaa
    10681 gctcacaaat aaagacagat tgtgtattcc agtgccattt ttccactgtt tcggttgcgt
    10741 tatcggtacg ctcacaatcg tgtcagcggg tggaacgatg gtgccgattc aagattacaa
    10801 tcctgaagtc gtgctccaaa cggtacaaaa agaaaaatgt acggcacttc acggtgtacc
    10861 gacgatgttt attagtgaac ttaatttacc gaatattcaa gaatttgatt tatcgtcgtt
    10921 gcgtactggt gtaatggcag gttcgacgtg tccaatcgaa gtaatgaaag atgtcattga
    10981 cgtcttagga attaaagata ttacgatttg ctacggtcaa acggagtcat caccagtatt
    11041 gacacagacg cgtacagaag acaacattac acgcaaagta gaaacggtcg gtcgtgcgct
    11101 tccaaatacg gaagtaaaag tagtagcacc tggtacgaat gaagagctac cacgtggtgt
    11161 gcaaggtgaa atcgtcgcac gtggctattg tgtgatgaag ggctattaca aaaatcaaga
    11221 tgcaacagct gaagcgattg atcaagatgg ctggttgcat acaggagacc tcggcacgat
    11281 ggatgaagat ggttacttaa aagtgacagg tcgtttgaaa gatatgatca ttcgcggcgg
    11341 agaaaacatt tatccacgtg aaattgaaga gtttttatat agtcatccac aaattttaga
    11401 cgtgcaagtc gtcggtgtgc cagatccgaa atacggggaa gaattggccg catggattat
    11461 tccgaaagac tcatcgcttg atgaagcgga cattcgcgca tattgtacag gcaaaatttc
    11521 gcgtcataaa attccacgac atattttatt cgtagaagaa tatccgatga cagcctctgg
    11581 taaaattcaa aaatttaaat tgcgtgaagc gtttatagag gagggatagc atgtttcaaa
    11641 agattttaat cgcaaaccgt ggtgaaatcg cacgtcgcgt cattcgcact tgtgacaaac
    11701 tcggcattca aacggttgcg atttattcaa cagccgatgc agatagttta catgtacgcg
    11761 atgcaagcga atcgtatgca gtcggtgaag cacaagtaaa tcaaagttat ttaaacgttg
    11821 acgcaattat tgatgttgca aaacgttcag gcgcggaagc tattcatcca ggatacggtt
    11881 tgctttctga aaatgcggat tttgcacgtg cagtcgaagc ggctggtctt acgtggatcg
    11941 gtccgaaacc agaagtcatt gaagaaatgg gcagcaagtt agcggcgaga caacgaatgg
    12001 aagatgcggg cgtgccgatt attaaaggta cgaataatgc agttgcagat gtagatgaag
    12061 cagcgcgtat tgctggggac atcggttatc ctgtgatgtt aaaagcatct gcaggcggtg
    12121 gtggtatcgg tatgcaagcg gtacatgacg aagaagccct tcgcaaagca tttgatggca
    12181 accaacaacg cgccgcaaac ttttttggag atggcacgat gtttgtcgaa caactcattg
    12241 aagcgccaca tcacgtggaa gtgcaagtgt tagcagatac gcatggcaat gttattccag
    12301 tgtttgaacg tgaatgctcg gtgcaacgtc gtaatcaaaa agttgtcgaa gaagcaccat
    12361 caccatttat ttcgccagaa acacgtgaac aaatgcttga tgcagcggtt gccgcagcac
    12421 aggccattaa ctatacgaat gcagggacga ttgagttttt agtcgatgct tcgcaaaact
    12481 tttacttttt agaaatgaat acgcgcttac aagtagagca tccgattact gaagaaattt
    12541 cagggttgga tctcgtcgag tggcaattga aagtcgcaag cggtgaaacg ttaactgtga
    12601 agcgtgaaga tttaacaatt aatggtcatg caattgaagt gcgtatttac gcagaagacc
    12661 cggtgaagtt tttcccatca ccaggaacga ttcaaacgtt ttcgattcca gaaggtgaag
    12721 gtattcgcca tgagctaagc gttgaagctg gcagtgtcgt cacaccgttt tacgacccga
    12781 tgattgcaaa acttgttacg cacggtgata cacgtgacgt agcgattgaa cgaatgactg
    12841 acgcgcttga tcaatacgaa gtgacaggta ttaaaacgaa tattccattg ttacgaaaaa
    12901 taatggcaca ccccgttttc aaaagtggtg tcacaacgac aaaatttatt gatgaatata
    12961 aggaggaatt aaaatgatga ttaaatcaga gatggcaggt acagtgtgga aagtgttagt
    13021 aaaagaaggc gacacagtag aagaaggtca agaagtcgta atcttagaat caatgaagat
    13081 ggagattcct gtagaagcag aggagtcagg cactgtgaag cgcgtcatcg taagtgaagg
    13141 tgactttatc gagttggatg cagatttagt tgaagtagag taggtgacgt cgatgttgcc
    13201 aaacaatgtg cgtttgaaag aagttggacc gcgagatggg ttacaaaatg aaaaggcatt
    13261 gattgatacg gcggataaag ttgcactcgt caatcaatta agtgaaacag gcctcgatta
    13321 tattgaagta acaagcttcg ttcatccgaa atggattccg caacttgcag atgcagttga
    13381 tgtgttaacg caaattgacc gcaaaccagg ggtaacgtat gcagcgctcg tgccgaatat
    13441 gaaaggactt gcgcgcgccc ttgaagcaaa tgttgatgaa gtaagcgtct ttatgtctgc
    13501 atcagaaggg cataatcgcg aaaacattaa caaatcgatt gcagaaacat ttccggtatt
    13561 aagagaagtt gtcgaagcag cgaaagcagc tggcaaaacg gtgcgtggat atgtatcgac
    13621 agtgattgct tgtccatatg atggctatac gaagcctgag caagttaaat atgtggcaga
    13681 tcatttattt gaaatgggcg ttgatgaaat ttcgcttggc gatacgattg gggtagcagt
    13741 gccaccccaa gtagaaacat tattagatga actgatgaaa cattacgcgc ctgaaaaatt
    13801 ggcgatgcat tttcatgata cacatgggac ggcactagcg aatattgttg cgagtttacc
    13861 gtatggtatt acgacatttg atagtgcgat tggtggtctc ggtggttgtc cttatgcgaa
    13921 aggtgcatct gggaatgtgg cgacagaaga cgttttatat ttgttacatt caatgggcat
    13981 cgaaacaggt gttaatctcg atcaaatgat gaaagcgtct caatttatgg agcaaaaaat
    14041 caatcgtcaa ctgacatcga aacaaatggc gattttcaga ggtgaacagt catgacgctc
    14101 gtacagttag aaatcaaaga tcggttagca attattacgc taaaccgtcc agaggcagcg
    14161 aatgcgatgt cgcgtgcgat gttacaagca tatattgaag tgctagagca agtcgctcac
    14221 gatcgttcga ttcgcgttgt gttattaaca ggtgctggtg aaaaagtatt ttgtgccggt
    14281 gcagacttaa aagaacgtca gcaaatggac gaagtgatga cgaaaaagac gattgcatta
    14341 attggtgaag ccatcacgaa aacggagcaa ttgccacaac cggttattgc aatgatgaac
    14401 ggtatggcac ttggtggtgg gctagagcta gcactcgctt gtgatattcg tgtcgcggcg
    14461 acgacagcga agctcggttt gacagaaaca tcgctcggca ttattccagg agcaggtggt
    14521 acgcagcgtc tacctcgtct catcggaaca ggtcgtgcaa aagaactcat ttatactgcg
    14581 cgtcgtatta cggcggaaga agcggtacaa ctcggtcttg tcgagcacat ttacattcaa
    14641 gaattgcttc gagaagaaac ggagaagttg gcgcttgaaa ttgcagaaaa tgcgccactg
    14701 gcattaattc aggcgaaacg tgccattcaa caaggcatgc agacggactt aaaaacaggt
    14761 atcgacattg agcgtctcgc atatgaacgt ttattgcaga cggaagatcg actagaagga
    14821 ctggcagcgt ttaaagaaaa acgtgcgcca caatacgaag gcaagtaggg aggaacgaac
    14881 atgacggaaa atacgtatac ggaaaaatcg taccgagatt ataaagaaga tatcgttgca
    14941 ggtggtgcac cgaaatatca cgagaaaaat agtgcgcaag gtaaattatt cgtccgcgat
    15001 cgtttaaagc gtttgtttga tgatgagttt cttgtagaag acggtgcttt tgcgaatgta
    15061 ctagcaggcg atttaccagc agatggcgtt gtcacaggga ttggtaaaat tcatggtcgt
    15121 accgtttgtg tcatggcaaa tgactcgacg gtaaaagcgg gttcttgggg gaaacgtaca
    15181 gttgagaaaa ttttacgtat tcaagaaacg gctgaaaaac tggaagtacc actcctttat
    15241 ttagtcgatt cagcaggcgc acgtattacc gatcaaattg agatgttccc aggccgtcgt
    15301 ggtgccggtc gcattttcta taatcaagta aaattatcgg gtcgcattcc acaaatttgt
    15361 ttactattcg gtccatctgc agcaggtggt gcgtacattc cggccttttg cgatattgtc
    15421 gtcatggttg agaaaaacgc gtcgatgtac ttaggttcgc cacgtatggc tgaaaaagta
    15481 atcggtgaac acgtagattt agaaacgatg ggcggggcaa aaatgcattg tagcgtttca
    15541 ggctgtggtg atgttttagc gaaaacagaa gaagaagcga ttgactacgc gcgtcgctac
    15601 ttaacatact tcccgcaaaa cttccgtgaa aagccagcat tacaagcacc ggaagagccg
    15661 acgccagcag aaaaaacgct tgcggaaatt attcctgaaa atcaaaatgc ggcgtttaac
    15721 atgcatcatt taattgaacg tgttattgac cacggctcat tttgtgaaat taagaaattg
    15781 ttcgcaaaag aactaattac aggtcttgca cgtattaatg ggcaagcggt cggtattatc
    15841 gcgaaccaac cgaaagcaaa aggtggcgtc ttattccatg attcagcgga taaggcggca
    15901 aaattcatta acttatgtga tgcgttccac attccactta ttttcttatc tgacgtacct
    15961 ggctttatga tcggtacaca agtggagcgt caagggatta ttcgccacgg tgcgaaaatg
    16021 atctttgcga tgagtgaggc gacggtgcca aaattatcgg ttatcgtacg taaagcatat
    16081 ggcgcgggtc tatatgcgat ggcaggtcca gcatttgagc cagatgcatg tatcgcgtta
    16141 acgacagcgc aaattgccgt aatgggacca gaagcggcta tcaacgctgt atatgcgaat
    16201 aaaattgcgg cgttgccaga gtcagaacgc ccagccttta tcgcgcaaaa aacagaagaa
    16261 tatcgtgaag aaatcgacgt atatcgttta gcttctgaac ttgttgtcga tgacgtgatc
    16321 gaaccaaatg agctacgtca ggcgcttgtt gagcgtttag aagtatataa aacgaaaaaa
    16381 ttaacattta cagagcgaaa acatggtgtt aatccagtat aataaaagta acaaatgaag
    16441 cagcccttgc aatgagggct gtttttttta ggaggatttc aggggaatga agaaaacatt
    16501 aggggcattt acacttatcg ctgcacttac aataccaacg atggcacaag cggcacaaaa
    16561 tccatcttcg ccgacgatta acaaaatgtt aacggatact gcgaaaaaat ataatatacc
    16621 accagaagta ttaaaaggtg tggcgatgca ggagagtggc tggcgtcaat ttgatgaaaa
    16681 aggtacacca cttgtagctg aagataacgg tatcggcatt atgcaagtaa cgacgaagca
    16741 atccaatatt tctgatgatt cgttgaaaaa tgatatcgct gcgaatattg aagaaggcgc
    16801 gctcatttta aatacgatgt ataaccgtag cagtacgcct aaagtaactg gagaccgtca
    16861 agacattgaa gattggtttt ttgcagttat cgcttataac ggtatggtgc ctagcaatag
    16921 tccagtcgtt caacaaacag gggcattaaa tgaaaaaagc tacggtcaaa aagtgtacgg
    16981 taaaatttat cgccaagact tttcaaatac tggccaacat cgcgtaacag cggaaaataa
    17041 agatgtgcaa ctgatggata ttttaaatat tcgtccgact aatgttacgt actacgaaaa
    17101 tccagctaaa atggtatttc aaaaatcaac gtttgaaccg acgagtcgtg tgacacgttc
    17161 aaactacgcc ttaaaagtaa aagatcgtgt gcttatgact gccaaaggtg ttaagctacg
    17221 tacgaagcca tcaacggtta acagtgcaga ggtcacaaaa ttagcacaat atgaacgtgt
    17281 gacaattacg gggccttatg tttttgatac gcaacaacca aataaccgct tcgtttggta
    17341 tcctgtccaa acgtcatcag gtcaaaaagg ctacatcgct tcagcttata tgcagcatac
    17401 atatccaatg attgaaacgc gtaatgtgac aatgtatgca ggtgaaaatg tcacatctta
    17461 tgtacgtgct attgatgccg aagatggtga cgtatcaaaa tatgtaacag ctaactttaa
    17521 cagtggaaca cccggtgttt acgacgtacc ggtaacggtc cgcgatagct cagcgaagac
    17581 gacgatagaa acaatccacg tgacagtgaa gcctgcagtt gtcattgcaa aaccaaaagt
    17641 gaaagcttta aaggcactag gcggtaaaaa agtaaaagtg acaattgcgc cagtaaaagg
    17701 tgctgttcgt tacgatattc aatacgcaac gaacaaaaac atgaaaaatg cgaaaacggt
    17761 gaaaacaaca gcaacatcaa aaacattaac aaaactaacg aagaaaaaac gttattacgt
    17821 acgtgttcgc gcgtacgtca cagtcaatgg taaggcgaaa gctggtgcat atggcgctgt
    17881 aaaaacaatc gtcgctaaat aaagacaagg cgtatgcatg aagcatacgc cttttttagt
    17941 atgtaaaaat gtaaacaaat aaacgtattt acacaaaaag agcgctatga cagcgcccta
    18001 gccctctatg aagttaaaaa acaaatcatt tgaagctcat ttaaatactt gccatctggc
    18061 attttcatta cttttgggtc tggacataaa atctcaaagc ccattcgttc atacaactta
    18121 atagccggta ccatcgtatc aacgactgat agacgaagtt gttcaagttc atcgttttgt
    18181 cgggcgtcgt tgacgattcg ttcaaacatc gctttactat aaccttttcc tcggtgctca
    18241 ggtgctaaat acacaccgac gatttgcgca atatgtttca ttttctcatg tccattttgt
    18301 acgactgttg taacgccgac gagttcatga ttgtcgaaca caccgtaagt ttttgaaagt
    18361 gcgtccgcta acatttcctc gtatgtgtct acatcttttt ggcgttcttc ttcgtacgtt
    18421 ggtaaaaatg attcaggttc ctcttttaca gcgcggtgcc gaatcgctaa gtaattactt
    18481 gcatcatctt ttgttaatat acgaatatcc atgaaaacgc ccccccttgt tcaattacta
    18541 ttctttaccc attttggaag gggatgaaaa ggcatctttt tgtaaatcga catttaataa
    18601 ttgttctttc gtcggtgctt gttgaatgtc gcgttgtaat tctaagcgca ttttttctgt
    18661 ttccattttg tagttgtcat atttcaattg ttctaatttg atttgctcac gcatcatttc
    18721 aatttcaagt tttttcgttt tctctcgact tttaatcatt ctttccgcta agcttgctgc
    18781 cgctgtaata gcgacgatca cgacaatagc aatccaaaac atattgatgc cccctttttg
    18841 ttcgtacgta atatacgaaa tacaatataa aaagtttcaa tattcacaaa aatttaaagt
    18901 gttgtttacg cacacttatt tgaggtaaac attacattaa agggagtgat gacatgtcag
    18961 tagaaacgaa aacgttagca gatggtcaca aaataccagt cattggattt gggactgttt
    19021 ttatgaaagg tgaagcagcc gcagaaggtg ttgcttcagc gattcagcat ggctatcgat
    19081 tgattgatac agctattcgt tacgacaatg aaggtgcagt cggagagggg attcgtcggt
    19141 caaatgtgcc gcgcgaagaa cttttcgtca catcgaaatt acgtgcccaa tattatgacc
    19201 gaaaagtcgg ttacgaaatg attgaagaat cgttgttccg tatggggctc gattatttag
    19261 acttatattt actacattgg ccaaatccga agcaagacaa gtatgtagaa gcatggcaga
    19321 ctttaattga ggcgcaaaaa gaaggacttg tgcgctccat cggtgtttgt aactttatgc
    19381 ctgaacattt aaatcgttta gaagaagaaa cgggcgtgct accagtcgtc aatcaaattg
    19441 agttgcaccc gtacttttca caagaagaga tgcgtgctta taacgaatcg aaacaaattg
    19501 tgaccgaatc gtggagtcca ttaagccgcg gacgtaccgt tatttatgat gaaacgcttc
    19561 aaaaaattgc ggcgcataaa aataaaacga ttggtcaaat tattttacgt tggcattatc
    19621 aaattggtgc ggtcgcgatt ccgaaagcag cgtccgaaaa acatcagctt gaaaatttag
    19681 cgatttttga tttttcatta acagacgaag aaatggcatt gatcaatgca ttgacgcaag
    19741 ataatggtcg cattgataac caagatccac gtgaatatga agaattttaa taaaaaaacc
    19801 gtatcacctt atgtcaggtg gtacggtttt ttgtttacat aaagcgtggt agcacgatac
    19861 caccgtataa aaatgcgccg ataatgacga aagcagggtg atattttttc acttggagcg
    19921 cccaatatgc agccgcgccg attaataaaa attgtaagat gccgattttt tcaaatgatt
    19981 cagatgataa ttgccacata atgactgcca tcatgaccgc taaaattggt tgaatcaatg
    20041 tcgtcatgcc tttaataatt ggagaatcac gatgtttttg gagtactttc attaaaataa
    20101 tgacgaggaa aacggtcggt gcaatcgtcg caaataaagc aacaacgacg cctaacatac
    20161 cgtacgtatc atagccgaca aacgccgcaa tctttgttgc tatcggccca ggtagtgcat
    20221 tgccgagcgc cagcatattt gaaaaagctt cattatcgag ccatttataa tgtttcacga
    20281 tttggtcata cataagtgga atcgaagaag gaccgccacc gtaacctaaa atatttgcaa
    20341 tgaaaaagcc gagaaataat tgccaaagta cgatcatttt gcagccccct tttgacgacg
    20401 gaaaatttta aagtgtacgc taccgtatag taaaaatagt aatacagcga taccggaatg
    20461 aatgtgtagc acttgtagta agacaaatgc aatcgcgata aaaataatac tgaggacgat
    20521 gccgatccct ttaatcgatt tttgtgtaaa ttggagtgcc atttctagca acatgacgac
    20581 aacgactggc acaactgccg caatcatgcc catcacaact tttgaaccgc taagccagcc
    20641 gacgagagac aataacgcaa tcatcataat cgcacttggc acaatatgac aaagcacgcc
    20701 ccaaatcgcg ccgaatacac cacctaaacg atagccgata taaccagcca ttttcgtcgc
    20761 aattggtcca ggtaaggcat ttgcaatggc aagtgtttcg ctaaattcgt cgtcgctcat
    20821 ccacttataa ttttttactg cttcatgtcg aaaaagcggc attaccgaag gcccaccgcc
    20881 aaaaccgaaa ataccggagc gcaacatgcc gagtgcaagc tgtttcatct ctgttttcat
    20941 ctaattcccc ctataacttc ataccgatac ggcttttata acgtttaatt aaaatttgac
    21001 tatcaacgct cataatcccc ggaagcggat aaaggcgttg ttctaaaaat aattccatat
    21061 cttgattgtt tttgaacaag ccatgcatat gcaatttact cggaccggtc atatggtaaa
    21121 gacttgagac gttcggatct tccgctaacg tatctgctac ttgttgcaaa tattttggcg
    21181 ccacttctac gttgaaaaat gcggatactt gtaagcccat tttttcggga ttaatgactg
    21241 cggagaaacg ttcaatcaca ccttgctcca ttaaatgttg gacacgtgcc tgtacagcaa
    21301 cacgcgataa attaacggct tttgataaat ctgtgtaaga catgcgccca tcttcattga
    21361 gaagtgcaac aattttggtg tcgatatcgt ctagtaaaac tttttctttc ataatataaa
    21421 acctcctctt tgcattgctt atataagtat tttcaacaaa atgtctatta atattgccta
    21481 tttgtgacaa attgtttgtt agataattca tattgtacac gaaatgaaga tgtcggtgat
    21541 tgaaaattgg taaaaaatgc attttgtctt aaattaaata aattcatatt tttggtctat
    21601 acaaaaagta agaaaattat ataaaaaatg aacgtttcgt atatataaat gtgtatttac
    21661 aactaaaaag atatatgtga tagggaactg acctaaagaa ttgagacaac ataaaaagag
    21721 aaagacactt tcaaggtaca aaaactttgg aggtgttttt tgatgggcaa aaaacaagta
    21781 tattcgtatg aaacaaaata aaagcgattg aaatgaaatt agcacaagtg ccaatgaaag
    21841 aaatgaagga ggtatgtggg attaaaaatg aaacccaaat ctatcagtag gtgaaatgct
    21901 ttaaagatgg ggagttgcat cgattagaat agccaattgg caagcaatat agctatagta
    21961 aaggacctta tgaagaaggc atgagtgaga tggaactgta ttgtaaaacc gaaaaagtat
    22021 catcataaac cagtaactgc cgcaattgtg gcagaaaacg tattaaacag ggattttaca
    22081 gtgagacgcc agcttaaagt gcaaaacatt ttattttgaa ggacttttga gaacaacaaa
    22141 tgaggttgtc gttcaaacct ttcaagcata catcaactac tatcataata cttgaatttt
    22201 ggcaaagtta aaccaccttt ctccagtaca gtaccggaaa aagatggttc aacaaaaatt
    22261 tgacggcgac tcctagggga aaagcatccg tcaaattcag ctaaaaagaa gtgtcttttt
    22321 cactgtctca cttttgtggg tcagttccag ttcgacgatg tctcttttct gattatttat
    22381 gaatgacttc aaatgttttc gatgataaac gttgttgtgc tgattcgtat tcgcggaata
    22441 attggtcgac gtattcacgt acgggttgta cgtctttaat cgcaccgatg ccttgaccgc
    22501 tgccccaaat atctttccaa gcttttgcgt ttgcgttcgc aaagctcatt tttgaagggt
    22561 cgctttctgc taagttgttc ggatcaagtc ctgcattttc aatagaaggt tttaagtagt
    22621 tgccatgaac gcctgtaaac aaattgctat aaacgatgtc atcagcgtta ctatcgacaa
    22681 tcatttgttt atagccttct accgcatttg cctcttctgt cgcaataaat ggtgaaccga
    22741 tatacgcata gtcagcaccc attgcctgtg cggctaaaat tgactgaccg gttgcgattg
    22801 agccagatag cgcaagcggg ccatcaaacc attcacgaat ttcttgcacg agtgcaaacg
    22861 gacttaatgc acctgcgtga ccacctgctc cagcagcgac ggcaattaag ccgtctgctc
    22921 ctttttcaat cgcttttttg gcgaagcggt tgttgatgac atcgtgtaaa catagcccac
    22981 cgtaactatg ggcagcatca aaaatttctg ggcgcgcacc gagtgatgaa ataataatcg
    23041 gcactttata tttaacgcac agttccatat cgtgctctaa acggtcgttc gtattgtgaa
    23101 caatttgatt aatcgcaaac ggtgctgcgg ggcgatcggg atttttcgca ttataacttg
    23161 ctagttcttc cgtaatttcc gcgagccatt cgtctaacaa ttctttcgga cgtgcattta
    23221 gcgctggcat tgacccaaca atccctgctt tacattgttc gataactaat tttggcgtgc
    23281 taataataaa catcggtgaa ccgatgacag gtaaacgtaa atttgcaatt gccgtcataa
    23341 aatcgcctcc aaggttacag tgttacattt actatactgt atttttttgt aaaaaaatat
    23401 aagcaatatg taggagattt taagcgtaaa gcattatttt cttcgttttt tgagcatatt
    23461 ttatatattt ctaaaaatag aataggacta agaaaagaac attatgaaaa taatgtgaca
    23521 aaagggtaca aaagacctgt tagaaatgaa aacaacaggg aatataaaaa ttagaacttg
    23581 ttattgtcat acattcatga gggcatgacg ataaaaatat gatgttatag aaaggagaaa
    23641 tgcacaatgc taagctttat ttggtatatc attattggtg gtattttagg ttggctcgga
    23701 ggtcttattt tagggaaaga tattccaggt ggtgtcatcg gtaacattat tgccggtatt
    23761 attggtgcgt tcatcggtgg ttcattatta ggccactggg gtccgaaagt aagtgacttc
    23821 tatatcttcc caacattatt aggtacgatt attttaatct taattgttgg tttcattatg
    23881 aaagcacttg gtaaaggtaa atagttgtat ctacatttat agccatgtta tactacaaat
    23941 aattaaaagg tacgttatgg aggagtctgt cacattaggg aaattatgcc cttctgtgac
    24001 ggactttttt ttggcgttcc ttttattttt ttacatttta gggaaataac atcaaaaagg
    24061 aggggtttta tgcaattggc aattattttt ttacc
//
