⚠ About the relative abundance profile

The relative taxonomical abundance data (pre-processed using a unified analysis pipeline) was retrieved from curatedMetagenomicData resource [Edoardo Pasolli, et al. Nat Methods. 2017;14(11):1023-1024]. Data retrieved here was pre-processed as unified relative abundance: at each taxonomic level (e.g., species, genus, family), the sum of microbial abundance of individual microbiota sample was 1, and relative abundance of each microbe was log10 transformed [relative abundance ranges from -7 to 0].

Healthy samples and disease samples (only disease types with >= 20 samples were included) were grouped by age periods, patients?country, or disease type to plot the relative abundance landscape using ggplot2 R package.

Data source: Phenotype comparisons were obtained from GMrepo . We summarized all comparisons that included healthy samples as controls and overlapped with microbes represented in MASI.

Note: LDA scores below 0 indicate taxa enriched in healthy samples, whereas scores above 0 indicate taxa enriched in disease samples.