Accumulating evidence about the interaction between human microbiota and active substances, especially for those therapeutically-relevant substances such as clinical used drugs and traditional medicines/herbs, is deepenning our understanding in the role of "our second genome" in human health and diseases, and opens new avenue for managing/treating human healthy problems/diseases by manipulating microbiota-human interactions.
A centralized and standardized database to catalog Microbiota-Active Substance Interaction (MASI) will be very useful for related research fields, including microbiota-related precision medicine, pharmaceutical research, food and nutrition research, clinical pharmacy, health management studies. Here, the MASI database is developed to cater this urgent need by providing manually curated MASI data from scientific literature. ⨠ See More ...
MASI includes multiple interaction types as follows:
Therapeutically-relevant Substance ---> Microbe
Microbes have relative abundance landscape [8799 human gut microbiota samples from 3,465 patients (18 diseases) and 5,334 healthy individuals from 24 countries]